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Articles 49471 - 49500 of 5211126
Full-Text Articles in Entire DC Network
Brief Review: Does Red Hair Phenotype Affect Propofol Pharmacokinetics Or Pharmacodynamics?, James Espinosa, Frank Wheeler, Robin Lahr, Sergey Medlenov, Alan Lucerna
Brief Review: Does Red Hair Phenotype Affect Propofol Pharmacokinetics Or Pharmacodynamics?, James Espinosa, Frank Wheeler, Robin Lahr, Sergey Medlenov, Alan Lucerna
Rowan-Virtua Research Day
Background: A persistent belief within Emergency Medicine and perioperative culture suggests that individuals with red hair require altered anesthetic dosing. While early studies demonstrated increased requirements for certain volatile anesthetics in red-haired individuals, this association is frequently generalized to propofol without clear supporting evidence.
Objective: To review current literature regarding the relationship between red hair phenotype (and MC1R variants) and propofol pharmacokinetics (PK) and pharmacodynamics (PD).
Methods: A focused narrative review of controlled human studies and relevant clinical outcome data evaluating propofol PK and PD in red-haired individuals.
Results: Evidence supporting altered anesthetic requirement in red-haired individuals primarily derives from …
Towards More Effective And Efficient Ite And Board Preparation In Emergency Medicine: A Conceptual Framework Using Personality Preferences (Mbti) To Inform Study And Test-Taking Behaviors, James Espinosa, Robin Lahr, James Lee, Alan Lucerna
Towards More Effective And Efficient Ite And Board Preparation In Emergency Medicine: A Conceptual Framework Using Personality Preferences (Mbti) To Inform Study And Test-Taking Behaviors, James Espinosa, Robin Lahr, James Lee, Alan Lucerna
Rowan-Virtua Research Day
Background: Preparation for high-stakes examinations in Emergency Medicine (EM) relies heavily on question-bank practice, rapid decision-making, and targeted review. Despite standardized board-preparation resources, trainees demonstrate substantial variability in study behaviors and perceived efficiency. The Myers-Briggs Type Indicator (MBTI), widely used in medical education for communication and self-reflection, may offer a framework for understanding differences in study and test-taking behaviors, though it is not designed as a predictive psychometric tool.
Objective: To review existing literature relating MBTI preferences to learning behaviors and academic performance, and to propose a conceptual framework linking personality preferences to board-style test-taking patterns in EM trainees.
Methods: …
Medical Clearance For Behavioral Health Patients In The Emergency Department: A Conceptual Overview Of Practice Variability, James Espinosa, Alan Lucerna
Medical Clearance For Behavioral Health Patients In The Emergency Department: A Conceptual Overview Of Practice Variability, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background: Patients presenting to the emergency department (ED) with behavioral health complaints frequently undergo medical clearance prior to behavioral health evaluation or admission. Substantial variability appears to be found in laboratory utilization, documentation language, and interdepartmental workflow.
Objective: To provide a conceptual overview of variability in medical clearance practices and to synthesize existing guideline recommendations and literature regarding routine laboratory testing in low-risk psychiatric patients.
Methods: Narrative review of professional policy statements, selected peer-reviewed studies, and operational considerations influencing emergency physician practice patterns.
Results: Evidence suggests that routine laboratory testing in psychiatric patients has low diagnostic yield and rarely changes …
The Case For Intraprocedural Ultrasound Guidance In Lumbar Puncture--From Landmarking To Navigation In Lumbar Puncture. A Conceptual Review And Research Agenda, James Espinosa, Frank Wheeler, Robin Lahr, Sergey Medlenov, Alan Lucerna, Henry Schuitema
The Case For Intraprocedural Ultrasound Guidance In Lumbar Puncture--From Landmarking To Navigation In Lumbar Puncture. A Conceptual Review And Research Agenda, James Espinosa, Frank Wheeler, Robin Lahr, Sergey Medlenov, Alan Lucerna, Henry Schuitema
Rowan-Virtua Research Day
Ultrasound guidance for lumbar puncture (LP) is well established for pre-procedural landmark identification, particularly in patients with difficult anatomy. However, most current approaches discontinue ultrasound prior to needle insertion, returning the operator to a blind technique. Current emergency medicine ultrasound guided intravenous line insertion demonstrate feasibility of real-time needle visualization. However, the development and adoption of real-time guidance in the setting of lumbar puncture remains limited. Prior simulation work demonstrated that ergonomics, operator experience, and workflow integration significantly influence performance in ultrasound-assisted LP (Horn, Espinosa et al., 2016). Here we make the case that LP is not a static targeting …
Protecting The Protectors: Supporting Emergency Department Security Officer Wellness: A Brief Conceptual Review And Research Agenda, James A. Espinosa Md, Paul Sarnese, Alan Lucerna
Protecting The Protectors: Supporting Emergency Department Security Officer Wellness: A Brief Conceptual Review And Research Agenda, James A. Espinosa Md, Paul Sarnese, Alan Lucerna
Rowan-Virtua Research Day
Background: Workplace violence in emergency departments (EDs) has been widely studied, yet the occupational wellness of ED security officers has received comparatively limited focused attention in emergency medicine literature.
Objective: To conceptually examine the role of ED security personnel within the emergency care environment and outline a research agenda addressing their wellness.
Discussion: Security officers frequently respond to behavioral crises, assist with restraint events, and help maintain safety for patients, visitors, and staff. These duties include vigilance between events, sudden physical exertion, and exposure to aggression. ED security work often follows a recognizable rhythm: baseline vigilance, rapid escalation response, physical …
Physician Bedside Communication Posture (Sitting Versus Standing) In Relation To Patient Satisfaction: A Focused Literature Review And Areas For Potential Research, James Espinosa, Alan Lucerna
Physician Bedside Communication Posture (Sitting Versus Standing) In Relation To Patient Satisfaction: A Focused Literature Review And Areas For Potential Research, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background:
Sitting during patient encounters is commonly recommended in communication training, with the assumption that it improves patient satisfaction. However, the empirical evidence supporting this recommendation in Emergency Department (ED) settings appears limited.
Objective:
To review the existing literature examining physician posture (sitting versus standing) and its association with patient satisfaction and perceived communication quality.
Methods:
Narrative review of ED and non-ED studies evaluating posture during clinical encounters, with attention to study design, sample size, setting, and outcome measures.
Results:
ED-specific evidence remains heterogeneous. Some studies demonstrate that sitting increases patients’ perception of time spent at bedside without increasing actual …
Olfaction And Clinical Cognition In Medicine: An Under-Theorized Sensory Modality In Healthcare, James Espinosa, Alan Lucerna
Olfaction And Clinical Cognition In Medicine: An Under-Theorized Sensory Modality In Healthcare, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background: Olfaction is the most evolutionarily ancient sensory modality and retains privileged neuroanatomical connections to limbic and threat-detection systems. Despite its biological significance, olfactory perception is under-discussed in contemporary medical education and academic literature, particularly in healthcare environments.
Objective: To examine olfaction as a low-bandwidth, high-salience diagnostic signal in medicine; to explore its neurobiological foundations; and to analyze its ethical, social, and professional implications within Emergency Medicine and other clinical settings.
Methods: Narrative synthesis of neuroscience, evolutionary biology, volatile organic compound (VOC) research, and clinical observational practice.
Discussion: Olfactory pathways bypass primary thalamic relay and project directly to limbic structures …
When The Clock Stands Still: Clock Time Vs. Experienced Time In The Emergency Department Brief Review: Neurobiology Of Time Perceptiontemporal Distortion As A Marker Of Cognitive Load And Operational Turbulence, James Espinosa, Alan Lucerna
When The Clock Stands Still: Clock Time Vs. Experienced Time In The Emergency Department Brief Review: Neurobiology Of Time Perceptiontemporal Distortion As A Marker Of Cognitive Load And Operational Turbulence, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background: Emergency clinicians frequently report that time during ED shifts can feel unusually slow or unusually fast. This shared observation has rarely been examined formally in emergency medicine. Altered time perception has also been described in high demand professions such as aviation, sports, military operations, and emergency response. Individuals often report time dilation during critical events and time compression during highly coordinated performance. These findings suggest that temporal perception reflects underlying neurocognitive responses to environmental demands. Emergency departments share many characteristics with these environments, including rapid decision making, task switching, and intermittent high stakes events.
Objective: Brief narrative review concerning …
Procedural Narration As An Important Cognitive Adjunct To Analgesia: Naming And Neurobiologically Grounding An Established Emergency Medicine Practice, James Espinosa, Alan Lucerna
Procedural Narration As An Important Cognitive Adjunct To Analgesia: Naming And Neurobiologically Grounding An Established Emergency Medicine Practice, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background: Experienced emergency physicians routinely provide real-time verbal guidance during procedures. Although widespread and intuitive, this practice has not been commonly conceptualized within pain neuroscience.
Objective: To name and mechanistically ground procedural narration as a form of cognitive analgesia, and to promote its intentional use and teaching in Emergency Medicine.
Methods: Narrative review integrating predictive coding theory, placebo/nocebo research, affective neuroscience, descending inhibitory pathway literature, and attentional modulation studies.
Results: Procedural narration reduces uncertainty, aligns expectation with sensation, modulates limbic threat processing, engages prefrontal cortical regulation, and supports descending inhibitory control of nociception.
Conclusion: Procedural narration is not a novel …
When Individual Implicit Bias Meets Ed System Turbulence: Expanding The Implicit Bias And Cultural Bias Conceptual Frame To Support Reflective Decision Making Through Both Individual Bias Reduction Strategies As Well As System-Level Design Approaches, James Espinosa, Alan Lucerna
When Individual Implicit Bias Meets Ed System Turbulence: Expanding The Implicit Bias And Cultural Bias Conceptual Frame To Support Reflective Decision Making Through Both Individual Bias Reduction Strategies As Well As System-Level Design Approaches, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background
Cultural and implicit bias have been widely studied as contributors to disparities in healthcare delivery. Prior literature has largely conceptualized bias as an individual-level cognitive phenomenon occurring within clinician–patient interactions. However, emergency departments (EDs) function as complex adaptive systems (CAS), characterized by time pressure, uncertainty, cognitive load, and environmental noise. These conditions may contribute to the expression of implicit bias in clinical care.
Objective
To reframe cultural and implicit bias in the ED as both an individual cognitive property as well as a system-dependent and modulated phenomenon and to propose that the operational state of the ED influences the …
A Systems-Based Approach To Supporting Resident Scholarly Productivity:Building A High-Throughput Academic Pipeline In Emergency Medicine Residency Training Through Poster Development Apprenticeship, James Espinosa, Alan Lucerna
A Systems-Based Approach To Supporting Resident Scholarly Productivity:Building A High-Throughput Academic Pipeline In Emergency Medicine Residency Training Through Poster Development Apprenticeship, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background:
Many residency programs require scholarly output; however, consistent and high-volume production of posters and publications can be challenging. Anecdotal evidence from a variety of programs suggests variability in outcomes across programs, often influenced by differences in mentorship, structure, and available scholarly infrastructure.
Objective: To describe a reproducible, systems-based model for generating high-volume resident scholarly output through alignment of expectations, culture, infrastructure, and faculty engagement.
Methods and Conceptual Model: We outline a multi-domain framework derived from sustained programmatic experience, incorporating structural requirements, leadership alignment, cultural reinforcement, workflow standardization, and active faculty participation. The model is supported by practical tools including …
Reframing The Step Study: The Health Significance Of Emergency Physician Step Count Results In Light Of Contemporary Benchmark Evidence, James A. Espinosa Md, Alan Lucerna
Reframing The Step Study: The Health Significance Of Emergency Physician Step Count Results In Light Of Contemporary Benchmark Evidence, James A. Espinosa Md, Alan Lucerna
Rowan-Virtua Research Day
Background:
The STEP study (2023), a prospective observational study of emergency medicine residents and attending physicians, demonstrated that clinicians rarely achieve the commonly cited 10,000-step benchmark during clinical shifts. Since that time, large-scale dose–response analyses suggest that substantial health benefits occur at lower step counts (~7,000 steps/day), with diminishing returns beyond this range.
Objective:
To reinterpret the findings of the STEP study in light of contemporary evidence regarding step count and health outcomes.
Methods:
We revisited observational data from the STEP study, which measured step counts during emergency department shifts across three campuses using pedometers. These findings were compared with …
Medical Journals As Complex Adaptive System (Cas) Reports: Reframing Journals As Structured Detection, Interpretation, And Feedback Systems In Healthcare, James Espinosa, Alan Lucerna
Medical Journals As Complex Adaptive System (Cas) Reports: Reframing Journals As Structured Detection, Interpretation, And Feedback Systems In Healthcare, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background Healthcare operates as a complex adaptive system (CAS) characterized by distributed agents, nonlinear interactions, and emergent behavior. Effective adaptation depends on mechanisms capable of detecting and redistributing signals from across the system.
Objective To conceptualize the medical journal as a structured CAS report and to examine its role in supporting system awareness among clinicians.
Conceptual Model Recurring journal sections—including original research, reviews, editorials, clinical cases, perspectives, humanities, and letters—function as distinct sensing and signaling channels. Together, they provide a multi-dimensional representation of system activity.
Implications Journals serve not only as repositories of knowledge but as adaptive communication nodes that …
Designing Patient Update Intervals In The Emergency Department: A Queueing-Theory And Operational Science Model Of Patient Updates And Progress Signaling To Improve Patient Experience, James Espinosa, Alan Lucerna, Henry Schuitema
Designing Patient Update Intervals In The Emergency Department: A Queueing-Theory And Operational Science Model Of Patient Updates And Progress Signaling To Improve Patient Experience, James Espinosa, Alan Lucerna, Henry Schuitema
Rowan-Virtua Research Day
Background Patients in the Emergency Department (ED) frequently experience uncertainty while awaiting diagnostic results, reassessment, and disposition. Even when clinical processes are progressing, prolonged informational silence may create the perception of that those processes are not advancing.
Objective To develop a conceptual and operational mathematical, queuing-theory based model linking bedside communication, conversational time, and informational silence to patient experience.
Methods A back-of-the-envelope operational model was constructed to estimate the time required for bedside update communication during a typical physician shift. A queueing-theory framework was applied to examine how intervals between informational updates influence perceived waiting burden. Concepts from queueing theory …
Identifying And Generalizing Best Attending Teaching Practices: A Proposal For The Use Of Appreciative Inquiry To Enhance Emergency Medicine Residency Teaching Practices, James Espinosa, Alan Lucerna
Identifying And Generalizing Best Attending Teaching Practices: A Proposal For The Use Of Appreciative Inquiry To Enhance Emergency Medicine Residency Teaching Practices, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
Background
Teaching in the Emergency Department (ED) occurs within a complex adaptive system characterized by time pressure, interruptions, and high cognitive load. Studying what works well in clinical teaching , even in such a challenging environment for teaching, may reveal reproducible patterns that strengthen educational culture, enhance resident learning, and accelerate the development of teaching expertise. In complex clinical environments, excellence is often present but under-recognized; An approach called Appreciative Inquiry provides a structured method for making it visible.
Conceptual Framework
Appreciative Inquiry (AI) offers an alternative approach by systematically studying successful practices rather than failures. AI explores how and …
Demographic Disparities In Contraceptive Use: Insights From Female Nsfg Respondents, 2015–2023, Adira Brenner
Demographic Disparities In Contraceptive Use: Insights From Female Nsfg Respondents, 2015–2023, Adira Brenner
Rowan-Virtua Research Day
Disparities in contraceptive use persist in the United States despite expanded access to family planning services. Historical policies and ongoing social determinants of health (SDOH) are significant drivers of the continued inequality in reproductive healthcare access and utilization. This study examines demographic trends in contraceptive use using data from the National Survey of Family Growth (NSFG) between 2015 and 2023.
Data were obtained from the NSFG and the National Center for Health Statistics (NCHS) datasets. A cross-comparison was conducted, focusing on variables such as age, race/ethnicity, and educational attainment.
The consensus was that contraceptive use increased to approximately 65% in …
Pcl And Pegdma Nanoyarns Feasibility For Antimicrobial Suture Applications, Wynn Bastianelli, Dominique Hassinger, Vincent Beachley, Sean Mcmillan
Pcl And Pegdma Nanoyarns Feasibility For Antimicrobial Suture Applications, Wynn Bastianelli, Dominique Hassinger, Vincent Beachley, Sean Mcmillan
Rowan-Virtua Research Day
Abstract Title: PCL and PEGDMA Nanoyarns Feasibility for Antimicrobial Suture
Nanofibers represent an innovative class of materials with diverse applications, including tissue engineering and drug delivery.1 Among the most promising areas of research is their use in surgical sutures, particularly for complex orthopedic injuries with high re-tear rates. Polycaprolactone (PCL) nanofibers have shown promise as alternatives to standard sutures as their unique properties support superior healing compared to standard materials.2 Our lab aims to further optimize these healing capabilities by adding Poly(ethylene glycol) dimethacrylate (PEGDMA), a molecule that tethers peptides to PCL nanoyarns, developing a suture with greater …
Atomoxetine Enhances Specific Dimensions Of Cognitive Performance In A Rodent Strategy Shifting Assay, Jessica Ivanov
Atomoxetine Enhances Specific Dimensions Of Cognitive Performance In A Rodent Strategy Shifting Assay, Jessica Ivanov
Rowan-Virtua Research Day
Title: Atomoxetine enhances specific dimensions of cognitive performance in a rodent strategy shifting assay
Authors: Jessica Ivanov, Christopher P. Knapp, Barry D. Waterhouse, Rachel L. Navarra
Objective: Cognitive flexibility, a domain of executive function, supports adaptive shifts in behavior in response to changing environmental demands and task contingencies. Deficits in this capacity are common to neuropsychiatric disorders such as Attention Deficit Hyperactivity Disorder (ADHD), where improper regulation of the catecholamine transmitters dopamine (DA) and norepinephrine (NE) within the prefrontal cortex (PFC) has been implicated. Atomoxetine (ATX), a selective NE transporter (NET) inhibitor, elevates levels of NE and DA in the …
Obesity Paradox In Post-Cholecystectomy Outcomes: A Bmi Class–Based Trinetx Analysis At 6 Months And 1 Year, Jashanveer S. Johal, Mahmoud Al-Bataineh, Bianca Patel, Archana Salek, Om Patel, Jason Hyman, Yecheskel Schneider, Abdallah Hussein
Obesity Paradox In Post-Cholecystectomy Outcomes: A Bmi Class–Based Trinetx Analysis At 6 Months And 1 Year, Jashanveer S. Johal, Mahmoud Al-Bataineh, Bianca Patel, Archana Salek, Om Patel, Jason Hyman, Yecheskel Schneider, Abdallah Hussein
Rowan-Virtua Research Day
Background: Obesity is traditionally associated with higher perioperative risk, yet observational data suggest an "obesity paradox" in which obese patients experience comparable or better outcomes than non-obese peers. We evaluated the impact of obesity (BMI ≥30 kg/m²) and obesity class on post-cholecystectomy outcomes.
Methods: A retrospective cohort study was conducted using the TriNetX global federated network. Adults undergoing cholecystectomy with BMI < 30 kg/m² were propensity score–matched 1:1 to those with BMI ≥30 kg/m², yielding 81,048 patients per group. Primary outcomes included choledocholithiasis, procedural complications, need for ERCP, and ED/inpatient utilization; secondary outcomes included mortality, respiratory and cardiovascular complications, and upgrade of care. Outcomes were assessed at 6 months and 1 year. A prespecified subgroup analysis compared BMI 30–39 versus BMI ≥40 kg/m² (40,238 per cohort).
Results: Obese patients consistently demonstrated lower rates of major outcomes at both timepoints. At 1 year, BMI < 30 had higher risks of choledocholithiasis (9.1% vs. 8.0%; RR 1.13), procedural complications (3.8% vs. 3.1%; RR 1.22), ERCP (5.4% vs. 4.6%; RR 1.19), and ED/inpatient visits (30.3% vs. 28.8%; RR 1.05; all p< 0.001). Mortality was also higher in non-obese patients at 1 year (1.4% vs. 1.2%; RR 1.20). Within the obese subgroup, BMI 30–39 and BMI ≥40 had broadly similar complication and utilization rates, though 1-year mortality was lowest in class I–II obesity (0.8% vs. 1.0%; RR 0.85).
Conclusions: Obesity was associated with better post-cholecystectomy outcomes compared with BMI < 30 kg/m², supporting an obesity paradox in biliary surgery. BMI alone should not deter cholecystectomy, and perioperative risk stratification should incorporate factors beyond weight class.
Schizophrenia And Multiple Dka Episodes Leading To Neurocognitive Deficits In A 37yo Patient, Andrew Harmon D.O.
Schizophrenia And Multiple Dka Episodes Leading To Neurocognitive Deficits In A 37yo Patient, Andrew Harmon D.O.
Rowan-Virtua Research Day
Patient is a 37 year old female with a PPHx of schizoaffective disorder and PMH of type 1 Diabetes who has had numerous admissions to the ICU due to uncontrolled blood sugars in the setting of continued delusions and medication noncompliance. With continued episodes of DKA, patient continued to psychiatrically decline over the course of multiple years. Studies have shown that anti-psychotic treatment in schizophrenia can help improve cognitive functioning.
The Obstacles Of Performing A Retrospective Chart Review, Emily Reilly, Robert Hudrick D.O.
The Obstacles Of Performing A Retrospective Chart Review, Emily Reilly, Robert Hudrick D.O.
Rowan-Virtua Research Day
Introduction: This research project "Comparing timing of care for skin cancer patients with limited English proficiency who require interpretation during medical visits to patients with English proficiency" was accepted under the CREATE Grant. The hypothesis was that patients who require medical interpretation during their visits would show a longer period of time between noticing a skin lesion to definitive diagnosis. Previous research has shown improved health care outcomes, but has mixed results on patient satisfaction and health care experience. This poster aims to detail the limitations faced during the execution of a retrospective chart review from the perspective of a …
A Systematic Review Of Artificial Intelligence And Automation Bias In Radiology: Implications For Diagnostic Accuracy, Wesley Augustus Kim, Harshal Parmar, Nikhila Archakam, Akhila Archakam, Brandon Velazquez
A Systematic Review Of Artificial Intelligence And Automation Bias In Radiology: Implications For Diagnostic Accuracy, Wesley Augustus Kim, Harshal Parmar, Nikhila Archakam, Akhila Archakam, Brandon Velazquez
Rowan-Virtua Research Day
Background: Over 1,000 FDA-cleared AI algorithms are now available in radiology. A key assumption is that radiologists serve as the final safety net, capable of rejecting incorrect AI outputs. However, automation bias — the tendency to follow automated recommendations uncritically — may compromise this oversight.
Objective: To systematically review evidence on automation bias in radiology and quantify the degree to which radiologists follow incorrect AI recommendations.
Methods: Systematic review of PubMed (April 2016–April 2026) following PRISMA guidelines. Five studies met inclusion criteria encompassing mammography, chest radiography, and MRI. Meta-analysis performed using random-effects model with odds ratios calculated from raw data. …
The Use Of Prazosin In Individuals With Post-Traumatic Stress Disorder: A Scoping Review Protocol, Priyal Pritesh Shah, Marisa Riebesell, Afshan Khan, Amanda M. Carey, Emily Balog, Martin Forsberg
The Use Of Prazosin In Individuals With Post-Traumatic Stress Disorder: A Scoping Review Protocol, Priyal Pritesh Shah, Marisa Riebesell, Afshan Khan, Amanda M. Carey, Emily Balog, Martin Forsberg
Rowan-Virtua Research Day
Background: Post-Traumatic Stress Disorder (PTSD) is a prevalent and debilitating condition, and is most often associated with sleep disturbances such as nightmares, flashbacks, and heightened arousal. Prazosin, an alpha-1 adrenergic antagonist, has been widely used for PTSD symptoms, however findings across studies are variable and limited, and the scope of existing evidence is not well established.
Objective: This scoping review aims to systematically map the literature on the use of prazosin in individuals with PTSD across diverse populations, settings, and study designs.
Methods: The scoping review will be conducted in accordance with JBI methodology and reported following PRISMA-ScR guidelines. A …
Point-Of-Care Intestinal Ultrasound Is Associated With Reduced Colonoscopy Utilization And Improved Clinical Decision-Making In Ibd, Lakumi Dias, Ashlyn Mcclelland, Amy Glasofer, Charalampos Papachristou, Yecheskel Schneider, Sanket Patel
Point-Of-Care Intestinal Ultrasound Is Associated With Reduced Colonoscopy Utilization And Improved Clinical Decision-Making In Ibd, Lakumi Dias, Ashlyn Mcclelland, Amy Glasofer, Charalampos Papachristou, Yecheskel Schneider, Sanket Patel
Rowan-Virtua Research Day
Background:
Point-of-care intestinal ultrasound (IUS) enables real-time assessment of bowel inflammation, and it is underutilized in the United States. IUS provides visualization of bowel wall thickness, vascularity, and complications without radiation or bowel preparation. Prior studies demonstrate that IUS changes management and reduces reliance on invasive testing. This study hypothesizes that IUS will impact downstream clinical decision-making in a U.S. outpatient IBD cohort by decreasing invasive procedures and supporting appropriate treatment decisions.
Methods:
A retrospective cohort study was performed. Logistic regression and chi-square tests assessed associations between IUS use, colonoscopy referral, hospital utilization, and treatment modification. A derived “surveillance-due” variable …
X-Ray Versus Ct For Femoral Landmark Identification: A Systematic Review And Meta-Analysis, Akash B. Patel, Marzieh Saeedi-Hosseiny, Mohammad Abedin-Nasab
X-Ray Versus Ct For Femoral Landmark Identification: A Systematic Review And Meta-Analysis, Akash B. Patel, Marzieh Saeedi-Hosseiny, Mohammad Abedin-Nasab
Rowan-Virtua Research Day
Background Accurate femoral bone landmark identification is essential for orthopedic surgical planning, deformity correction, and fracture risk assessment. Radiography offers accessibility and low cost, while CT provides superior spatial resolution and three-dimensional visualization. Despite technological advances, no quantitative synthesis has compared these modalities specifically for femoral landmark identification.
Hypothesis CT provides superior measurement accuracy and interobserver reliability compared to radiography for femoral bone landmark identification.
Methods Following PRISMA 2020 guidelines, Embase, Scopus, and PubMed were searched from 2015-2025. Studies comparing radiography and CT for femoral landmark identification with quantitative outcomes were included. Dual-reviewer screening of 604 records yielded 27 studies …
Efficacy Of Repetitive Transcranial Magnetic Stimulation In Reducing Pain Intensity In Chronic Neuropathic Pain: A Sham-Controlled Analysis, Aprupa Alahari, Nathan Nhan, Cindy Nguyen, Samnit Gill, Simran Parmar, Annelisse Zara
Efficacy Of Repetitive Transcranial Magnetic Stimulation In Reducing Pain Intensity In Chronic Neuropathic Pain: A Sham-Controlled Analysis, Aprupa Alahari, Nathan Nhan, Cindy Nguyen, Samnit Gill, Simran Parmar, Annelisse Zara
Rowan-Virtua Research Day
Background
Chronic neuropathic pain (CNP) can be refractory to traditional pharmacologic therapies, giving rise to the investigation of non-invasive alternatives such as repetitive transcranial magnetic stimulation (rTMS). rTMS utilizes magnetic fields to modulate neuronal activity within specific brain regions, offering a targeted approach to analgesia without the side effects of systemic medication1,2,3,4.
Hypothesis
rTMS produces a greater reduction in reported pain intensity compared to sham stimulation in adults diagnosed with CNP.
Methods
A systematic review and analysis were conducted, utilizing PubMed and Embase (2004–2025) for sham-controlled randomized controlled trials (RCTs) and relevant meta-analyses. The review focused on outcomes such as …
Glp-1 Receptor Agonists And Neurocognitive Outcomes In Type 2 Diabetes: A Propensity-Matched Real-World Analysis Of Cognitive Impairment, Neurodegeneration, And Mortality, Om Patel, Shefali Waghray Do, Jashanveer S. Johal, Jason Hyman, Tatiana Gandrabura
Glp-1 Receptor Agonists And Neurocognitive Outcomes In Type 2 Diabetes: A Propensity-Matched Real-World Analysis Of Cognitive Impairment, Neurodegeneration, And Mortality, Om Patel, Shefali Waghray Do, Jashanveer S. Johal, Jason Hyman, Tatiana Gandrabura
Rowan-Virtua Research Day
Background: GLP-1 receptor agonists improve glycemic and cardiovascular outcomes in type 2 diabetes mellitus (T2DM), but their impact on neurocognitive and neurological outcomes remains incompletely characterized. We evaluated the association between GLP-1 agonist use and incident cognitive impairment, neurodegeneration, and healthcare utilization in T2DM patients without baseline cognitive deficits.
Methods: A retrospective cohort study was conducted using the TriNetX Global Collaborative Network. Adults (≥40 years) with T2DM and no prior cognitive impairment, Alzheimer's disease, Parkinson's disease, multiple sclerosis, or cerebral infarction were identified. Cohort 1 received a GLP-1 agonist (semaglutide, tirzepatide, liraglutide, or dulaglutide) after T2DM diagnosis; Cohort 2 received …
A Retrospective Comparison Of Dobhoff Nasogastric Feeding Tubes To Iris Feeding Tubes, Nishant Patel Oms-Iii, Justin Le Oms-Ii, Amy Glasofer Phd, Drnp, Rn, Emilio Mazza Md, Phd
A Retrospective Comparison Of Dobhoff Nasogastric Feeding Tubes To Iris Feeding Tubes, Nishant Patel Oms-Iii, Justin Le Oms-Ii, Amy Glasofer Phd, Drnp, Rn, Emilio Mazza Md, Phd
Rowan-Virtua Research Day
Background
Postpyloric feeding is essential in critically ill patients. Traditional Dobhoff tube (DHT) placement, often performed blindly, is widely used due to low cost but carries risks of misplacement and reliance on radiographic confirmation. In contrast, Kangaroo™ IRIS (camera-guided) technology enables real-time visualization during placement, potentially improving accuracy and workflow, though at higher cost.
Hypothesis
IRIS-guided placement provides comparable safety and success to DHT, with similar procedural efficacy without increasing complications.
Methods
A retrospective cohort study was conducted using the electronic medical records from multiple Virtua Health hospitals (01/01/13, through 01/31/25), including 200 patients undergoing nasogastric tube placement with DHT …
Mid- To Long-Term Durability Of Thoracic Endovascular Aortic Repair For Blunt Thoracic Aortic Injury: Outcomes In ≥ 45 Comparator Cohort, Andrew Lawrence Frankini, Gianna Rose Zanghi, Margaret Schwab, Valentina Sara Sica, Larry Andrew Frankini Md
Mid- To Long-Term Durability Of Thoracic Endovascular Aortic Repair For Blunt Thoracic Aortic Injury: Outcomes In ≥ 45 Comparator Cohort, Andrew Lawrence Frankini, Gianna Rose Zanghi, Margaret Schwab, Valentina Sara Sica, Larry Andrew Frankini Md
Rowan-Virtua Research Day
Blunt traumatic thoracic aortic injury (BTAI) is a primary cause of mortality in blunt trauma injuries, with motor vehicle collisions representing the majority of cases.1-4 Thoracic endovascular aortic repair (TEVAR) is the standard of care for managing this vascular emergency.5 While TEVAR demonstrates favorable short-term outcomes, there is an insufficient characterization of cumulative mid- to long-term reinterventions and device-related complications in BTAI patients.
We conducted a meta-analysis/systematic review of studies reporting outcomes after TEVAR for BTAI in patients ≥45 years. This review was conceptualized as a comparator to the previously reviewed outcomes in younger patients (< 45 years) performed by Frankini et al. (2026)6, …
Efficacy Of Omalizumab And Exposure Immunotherapy In Reducing Allergic Immunological Response, Joshua James Novello, Michelle Lau, Josephine L. Miner, Mudassir A. Rahmani, Kimran Sandhu, Taha Umar
Efficacy Of Omalizumab And Exposure Immunotherapy In Reducing Allergic Immunological Response, Joshua James Novello, Michelle Lau, Josephine L. Miner, Mudassir A. Rahmani, Kimran Sandhu, Taha Umar
Rowan-Virtua Research Day
Background: Food allergy negatively impacts numerous children in the United States. Oral immunotherapy (OIT) and biologic therapy (omalizumab) are emerging promising strategies for desensitization. This literature review aims to compare the effectiveness of omalizumab and oral immunotherapy in pediatric populations.
Hypothesis: If the use of omalizumab therapy is used to treat children with food allergies compared to OIT, then there would be higher desensitization, lower post-treatment IgE levels, higher IgG4 levels, and decreased chance of a positive skin prick test.
Methods: PubMed, Embase, and The Lancet databases were searched using PRISMA guidelines to locate peer-reviewed studies evaluating …