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Articles 4591 - 4620 of 5154724
Full-Text Articles in Entire DC Network
The Eu’S Copyright Legislation For Generative Ai: Relevant To Indonesia?, Yolanda Simbolon
The Eu’S Copyright Legislation For Generative Ai: Relevant To Indonesia?, Yolanda Simbolon
Indonesia Law Review
Tremendously copyrighted works are used to train Generative AI (Gen-AI) at the epicenter of current sectors. In many countries, there is a dilemma as to whether the amount of data used may infringe copyright. The EU is the one that has regulations on the use of copyrighted works as text and data mining (TDM) to train GenAI. Meanwhile, Indonesia does not yet have a regulation, even though Gen-AI has been massively developed in Indonesia. Data has been used freely to train Gen-AI, even to modify works and damage the author’s reputation. This article investigates whether the EU’s copyright of Gen-AI …
Developing Leadership Competencies In Higher Education Institutions In The Sultanate Of Oman In Light Of Selected International Experiences: Proposed Mechanisms, Faiza Al-Shidi, Wajeha Al-Ani, Nisreen Saleh Saladin
Developing Leadership Competencies In Higher Education Institutions In The Sultanate Of Oman In Light Of Selected International Experiences: Proposed Mechanisms, Faiza Al-Shidi, Wajeha Al-Ani, Nisreen Saleh Saladin
Journal of Arts and Social Sciences
This study aimed to propose mechanisms for developing leadership competencies in higher education institutions in the Sultanate of Oman in light of selected international experiences. The study adopted a descriptive approach supported by comparative analysis through reviewing relevant literature, official documents, and previous studies. It also examined Oman’s efforts alongside selected experiences from Singapore, Malaysia, the Kingdom of Saudi Arabia, and Egypt.The findings revealed that Oman has made significant progress in developing leadership capacities within higher education institutions, supported by the objectives of Oman Vision 2040 and national initiatives led by relevant institutions. The comparative analysis also highlighted several successful …
Guarantee Of Minister Hamid Bin Al-Abbas And Its Impact On The Economic Conditions During The Time Of Caliph Al-Muqtadir (306-311 Ah/ 918-923 Ad), Adnan Abdullah Obaidat
Guarantee Of Minister Hamid Bin Al-Abbas And Its Impact On The Economic Conditions During The Time Of Caliph Al-Muqtadir (306-311 Ah/ 918-923 Ad), Adnan Abdullah Obaidat
Journal of Arts and Social Sciences
ABSTRACT This study aims to shed light on an important phase in the decline of the Abbasid state, specifically during the reignof Al- Muqtadir (295-320 AH/ 908 AD-932AD). This period witnessed intensified competition for the position of minister. Amid his rivalry, Hamid bin Al-Abbas assumed the ministry in the year 306 AH/ 918 AD, despite having no knowledge of politics and governance and no prior involvement in the political struggles of the time. The study seeks to examine the political and economic circumstances that led to his appointment, and to demonstrate how from the first days of his appointment, he …
Validation Of A Home-Based Tool For Preschool Children Fall Prevention: A Rasch Analysis, Devie Fitri Octaviani, Fatma Lestari, Indang Trihandini, Dadan Erwandi
Validation Of A Home-Based Tool For Preschool Children Fall Prevention: A Rasch Analysis, Devie Fitri Octaviani, Fatma Lestari, Indang Trihandini, Dadan Erwandi
Kesmas
Unintentional falls are a leading cause of injury among preschool children, primarily occurring in home environments, yet validated tools to assess household fall prevention capacity in low- and middle-income countries remain limited. This study aimed to develop and psychometrically validate the Home-Based Preschool Fall Prevention Instrument using the Rasch Measurement Model. A cross-sectional validation study was conducted in Depok City, Indonesia, involving 167 primary caregivers of preschool children enrolled in kindergartens selected through multistage cluster random sampling. The instrument was developed based on an etiological injury model, socio-ecological perspectives, and risk management principles, and comprised four main factors: child, home, …
Understanding Oral Habits And Malocclusion In School-Aged Children: Insights From Parental And Child Knowledge, Attitudes, And Practices, Maria Laurentia Sanjaya, Evan Raditya Pratomo, Markus Santoso, Agrippine Putricia Asaeli, Eveline Yulia Darmadi, Joy Janny Thenarianto, Jennifer Regina Putri Purwono, Eunike Jacquelyn Widarto
Understanding Oral Habits And Malocclusion In School-Aged Children: Insights From Parental And Child Knowledge, Attitudes, And Practices, Maria Laurentia Sanjaya, Evan Raditya Pratomo, Markus Santoso, Agrippine Putricia Asaeli, Eveline Yulia Darmadi, Joy Janny Thenarianto, Jennifer Regina Putri Purwono, Eunike Jacquelyn Widarto
Kesmas
Malocclusion is a prevalent oral health problem in children associated with oral bad habits, yet the extent to which parental and child knowledge, attitudes, and practices (KAP) influence orthodontic status remains insufficiently understood. This cross-sectional study investigated relationships between parental and child KAP, oral habits, and malocclusion in school-aged children, involving 67 child–parent pairs from an elementary school in Surabaya, Indonesia. Parental and child KAP as well as child-reported oral habits were assessed using a validated questionnaire. Children subsequently underwent standardized clinical orthodontic examinations, including alginate jaw impressions to produce dental study models, which were evaluated using the Index of …
Provincial Disparities In Adolescent Fertility In Indonesia: An Ecological Analysis Of Child Marriage, Median Age At First Marriage, And Family Development Index, Andi Nisa Fathimiyah Afidah, Milla Herdayati
Provincial Disparities In Adolescent Fertility In Indonesia: An Ecological Analysis Of Child Marriage, Median Age At First Marriage, And Family Development Index, Andi Nisa Fathimiyah Afidah, Milla Herdayati
Kesmas
Adolescent fertility remains a public health concern in Indonesia, with substantial variations across provinces. However, the evidence explaining provincial disparities using population-level indicators remains limited. This study aimed to examine provincial disparities in adolescent fertility and assess the association of child marriage, median age at first marriage among women, and the Family Development Index called iBangga with adolescent fertility across Indonesia. This ecological, cross-sectional study used aggregated data from 34 Indonesian provinces. Descriptive statistics, spatial visualization, Pearson’s correlation, and multiple linear regression analyses were performed. The mean adolescent fertility rate was 25.0 births per 1,000 female adolescents aged 15–19 years, …
Spatial Association Of Acute Respiratory Infection, Diarrhea, And Low Birth Weight With Stunting Prevalence In Indonesia, 2024, Dian Rosadi, Husaini Husaini, Triawanti Triawanti, Musafaah Musafaah
Spatial Association Of Acute Respiratory Infection, Diarrhea, And Low Birth Weight With Stunting Prevalence In Indonesia, 2024, Dian Rosadi, Husaini Husaini, Triawanti Triawanti, Musafaah Musafaah
Kesmas
Stunting remains unevenly distributed across Indonesia, but national evidence integrating spatial analysis and spatial regression is limited. This study examined the spatial distribution of stunting and its associations with acute respiratory infection (ARI), diarrhea, and low birth weight (LBW) across Indonesian provinces. An ecological cross-sectional study used data from the 2024 Indonesian Nutritional Status Survey. Stunting-only analyses included all 38 provinces, whereas analyses involving ARI, diarrhea, and LBW included 37 provinces with complete data. Spatial analyses used a row-standardized symmetric four-nearest-neighbor spatial weights matrix and included Global Moran’s I, bivariate spatial analysis, Local Indicators of Spatial Association, ordinary least squares, …
The Association Between Rapid Growth In Children Under The Age Of Five And Adolescent Obesity, Ratu Ayu Dewi Sartika, Fadila Wirawan, Iche Andriyani Liberty, Nurul Husna Mohd Shukri, Siti Arifah Pujonarti, Edy Purwanto, Munaya Fauziah
The Association Between Rapid Growth In Children Under The Age Of Five And Adolescent Obesity, Ratu Ayu Dewi Sartika, Fadila Wirawan, Iche Andriyani Liberty, Nurul Husna Mohd Shukri, Siti Arifah Pujonarti, Edy Purwanto, Munaya Fauziah
Kesmas
Early-life nutrition is a critical predictor of long-term health, yet the association between rapid early-childhood growth and adolescent obesity, particularly in relation to the “double burden of malnutrition,” remains under-researched in Indonesia. This study aimed to analyze the association between rapid growth and adolescent obesity. Data were obtained from the 1997, 2000, and 2014 waves of the Indonesian Family Life Survey (IFLS). This study included 641 children (aged 0–23 months at baseline) with complete anthropometric measurements across all three waves. Rapid growth was defined as an increase in z-scores of >0.67 in weight-for-age (WAZ), height-for-age (HAZ), or weight-for-height (WHZ) between …
Self-Management Interventions For Adults With Type 2 Diabetes Mellitus In Thai Primary Care And Community Settings: A Scoping Review, Sansanee Seetangkham, Supaluk Seetunya, Subhawan Yodprong
Self-Management Interventions For Adults With Type 2 Diabetes Mellitus In Thai Primary Care And Community Settings: A Scoping Review, Sansanee Seetangkham, Supaluk Seetunya, Subhawan Yodprong
Kesmas
Diabetes mellitus is a leading cause of mortality and economic burden, with significant impacts on health outcomes and quality of life. Effective self-management is crucial for controlling Type 2 Diabetes Mellitus (T2DM). Thailand has implemented diverse self-management interventions for adults with T2DM in primary care and community settings, but the components, delivery, duration, and outcomes of these interventions have not been synthesized. Following the Arksey and O’Malley framework, Joanna Briggs Institute guidance, and PRISMA-ScR, five databases were searched from inception to June 2025. Eligible English-language intervention studies involved Thai adults with T2DM in primary care or community settings. Study characteristics …
Environmental Perspective For System Dynamics Modeling Of Stunting Mitigation To Achieve The Sustainable Development Goals In West Sumatra, Indonesia, Elsa Yuniarti, Nabila Azzahra, Yulhendri Yulhendri, Heldi Heldi, Mery Delvina, Saskia Putri Azeli
Environmental Perspective For System Dynamics Modeling Of Stunting Mitigation To Achieve The Sustainable Development Goals In West Sumatra, Indonesia, Elsa Yuniarti, Nabila Azzahra, Yulhendri Yulhendri, Heldi Heldi, Mery Delvina, Saskia Putri Azeli
Kesmas
This study developed a system dynamics model to simulate stunting reduction in West Sumatra Province, Indonesia, by integrating infant and toddler health, maternal health, and environmental determinants. Secondary data from 2020–2024 on low birth weight, immunization, malnutrition, exclusive breastfeeding, maternal chronic energy deficiency, iron and folic acid supplement distribution, sanitation, and safe drinking water access were compiled from West Sumatra Provincial Health Office and Statistics Indonesia, and validated through consultation with five stakeholder institutions. Causal Loop Diagrams mapped feedback relationships among determinants and were translated into Stock Flow Diagrams using Powersim Studio 10. The model was validated through structural verification, …
Guardians Of The Record (Cs2 Edition): Heaps, Queues, And A Scarce Oracle, Ilan Goodman
Guardians Of The Record (Cs2 Edition): Heaps, Queues, And A Scarce Oracle, Ilan Goodman
Generative AI Teaching Activities
Students defend Wikipedia from vandals with data structures instead of infrastructure: a sliding-window edit-velocity tracker (hash map of queues), a hand-built binary min-heap, and a budget-bounded top-K selection decide which few suspicious edits earn a question to an expensive, rate-limited Oracle — a stand-in for a real LLM.
Guardians Of The Record: A Two-Tiered Streaming Cascade With Kafka, Flink, And A Real Llm, Ilan Goodman
Guardians Of The Record: A Two-Tiered Streaming Cascade With Kafka, Flink, And A Real Llm, Ilan Goodman
Generative AI Teaching Activities
Students build a streaming vandalism detector for live Wikipedia edits in which a fast rule-based tier decides which few of ~1,500 edits per minute are worth escalating to a slow, rate-limited real LLM (Gemini) — confronting the cost, latency, and failure modes of putting AI inside a production data pipeline.
The Role Of Male Early Childhood Teachers In Responding To Fatherless Parenting Issues Through Inclusive Education, Dyah Ageng Pramesty Koenarso
The Role Of Male Early Childhood Teachers In Responding To Fatherless Parenting Issues Through Inclusive Education, Dyah Ageng Pramesty Koenarso
Journal of Innovation and Teacher Professionalism
Growing attention to father absence and limited paternal involvement in Indonesia highlights the importance of professional and supportive practices in early childhood education (ECE). This study examines how male ECE teachers respond professionally to children whom they understand to experience father absence or limited paternal involvement. Using a qualitative case study design, the study involved 13 male ECE teachers from 13 institutions in South Kalimantan. Data were collected from May to August 2025 through 26 semi-structured interviews and 39 classroom observations and were analyzed using an interactive qualitative analysis approach. The findings show that participants provided pedagogical guidance, relational and …
Illinois Model Programs Of Study: Overview Guide (Draft For Public Comment), Education Systems Center
Illinois Model Programs Of Study: Overview Guide (Draft For Public Comment), Education Systems Center
Practitioner Toolkits and Resources
This draft is available for public comment through September 30, 2026. Share your public comment at:
https://forms.gle/VDKeCdf5HycEerMr7
Uhsp Student Handbook 2026-2027
Nihilistic Violence Aesthetics In Public Online Communication, Heath Nicholas Landress
Nihilistic Violence Aesthetics In Public Online Communication, Heath Nicholas Landress
Journal of Social, Behavioral, and Health Sciences
Public online communication has increasingly included violence-related content that is meme-based, ironic, visually stylized, multimodal, and only partially ideological. This comprehensive literature review synthesized research on online extremism, extremist memes, toxic multimodal content, dehumanizing digital communication, nihilistic violent extremism, warning behaviors, platform affordances, and youth-facing online environments. The purpose was to clarify what the literature had established; identify where the scholarship remained fragmented; and map research domains relevant to social, behavioral, public safety, and human services scholarship. The review used a structured, comprehensive literature review strategy supported by integrative synthesis procedures. The final corpus contained 34 scholarly sources, including 32 …
Dynamics Of Swimming Microorganisms At Structured Liquid Crystal Interfaces, Vajra Sabhapathy Badha
Dynamics Of Swimming Microorganisms At Structured Liquid Crystal Interfaces, Vajra Sabhapathy Badha
Graduate Doctoral Dissertations
Active matter systems are self-driven units that consume energy to generate motion and mechanical stresses, producing non-equilibrium states of broad physical significance. Examples include synthetic microswimmers and migrating cells. Motile bacteria are a widely studied biological example because their self-propelled motion, hydrodynamic interactions, and collective organization are strongly coupled to local environmental conditions. Their swimming is sensitive to interfacial viscoelasticity, ordering, confinement, and hydrodynamic boundary effects, making them useful for investigating how interfaces regulate active biological motion. Because bacterial accumulation and attachment at interfaces are central to colonization and biofilm formation, these interactions are relevant to both active matter physics …
The Difficulty In Defining The Construct Of Perseverance, Davon W. Ferrara, Linda W. Jones
The Difficulty In Defining The Construct Of Perseverance, Davon W. Ferrara, Linda W. Jones
Papers
Perseverance is a character virtue necessary for flourishing in the STEM disciplines; however, there are competing definitions of perseverance in scientific literature, which makes measuring the trait and researching its impact difficult. This work provides a review of the definitions of construct found within the literature and compares it to conflated terms such as grit, persistence, resilience, and self-efficacy that have related, but distinct meanings. Finally, we summarize the role of perseverance in STEM and what factors may influence its formation.
The authors gratefully acknowledge support from the Belmont Formation Collaborative and the Formation Scholars Cohort for Character Research and …
The Difficulty In Defining The Construct Of Perseverance, Davon W. Ferrara, Linda Jones
The Difficulty In Defining The Construct Of Perseverance, Davon W. Ferrara, Linda Jones
Posters
Perseverance is a character virtue necessary for flourishing in the STEM disciplines; however, there are competing definitions of perseverance in scientific literature, which makes measuring the trait and researching its impact difficult. This work provides a review of the definitions of construct found within the literature and compares it to conflated terms such as grit, persistence, resilience, and self-efficacy that have related, but distinct meanings. Finally, we summarize the role of perseverance in STEM and what factors may influence its formation.
The authors gratefully acknowledge support from the Belmont Formation Collaborative and the Formation Scholars Cohort for Character Research and …
Writing Together, Writing Differently: Collective Authorship As Reflective Practice, Thanh Thao Le, Trut Thuy Pham
Writing Together, Writing Differently: Collective Authorship As Reflective Practice, Thanh Thao Le, Trut Thuy Pham
The Qualitative Report
This article examines collective authorship as a reflective and ethical research practice within a sustained program of co-authored qualitative, post-qualitative, linguistic, and reflective inquiries into teacher reflection, professional learning, language, silence, and recognition. It offers an oral-history-informed reflective methodological account of a writing collective and asks how collective authorship became a methodological practice through our collaborative writing process. The primary materials were shared drafts, margin comments, revisions, silences, version histories, short reflective notes, and remembered writing encounters. Teacher-reflection texts and related professional writing materials from our broader research program formed the secondary materials around which the writing process unfolded. Analytically, …
Competition Policy Meets Environmental Regulation: A Case For ‘Green’ Antitrust, Marie-Laure Cabon-Dhersin Dr., Joanna Poyago-Theotoky, Natacha Raffin
Competition Policy Meets Environmental Regulation: A Case For ‘Green’ Antitrust, Marie-Laure Cabon-Dhersin Dr., Joanna Poyago-Theotoky, Natacha Raffin
Fondazione Eni Enrico Mattei Working Papers
We explore the interplay of competition and environmental policies to address the question of whether green antitrust has beneficial effects in terms of both en vironmental and consumer welfare performance. We focus on two environmental policy tools, an emission tax and an emission standard, and explore three par ticular configurations: competitive ‘green R&D, collaborative ‘green’ R&D in the form of a joint lab, and the benchmark case of no ‘green’ R&D. Firms compete in the product market by selling a homogeneous product, either by setting prices (Bertrand competition) or quantities (Cournot competition) while facing convex costs. We show that ‘green …
Participatory Culture Fandom Nctzen: Studi Kualitatif Interaksi Penggemar Dalam Akun X (Twitter) “Hijau Bersama Indonesia” Pada Aksi Demo Agustus 2025, Fania D. Anjani, Nayla L. Augusty, Kayla Marsyanda, Dian K. Sari
Participatory Culture Fandom Nctzen: Studi Kualitatif Interaksi Penggemar Dalam Akun X (Twitter) “Hijau Bersama Indonesia” Pada Aksi Demo Agustus 2025, Fania D. Anjani, Nayla L. Augusty, Kayla Marsyanda, Dian K. Sari
Paradigma: Jurnal Kajian Budaya
This study examines participatory culture and fan activism practices within the NCTzen fandom community through the X (Twitter) account “Hijau Bersama Indonesia” during the August 2025 Demonstration. This study stems from the growing phenomenon of fandoms that are no longer limited to entertainment consumption, but also play a role as social actors in responding to environmental and humanitarian issues in the digital space. This research uses a qualitative approach with a virtual ethnography (netnography) method. Data was collected through online observation, in-depth interviews with actively involved fans, and digital documentation in the form of posts and interactions on the X …
Transmutation Of Psychological Phenomena (Academic Burnout And Fomo) Into Cyanotype Art Creation, Zulfan Ali Mujtaba, Adi Kuntoro
Transmutation Of Psychological Phenomena (Academic Burnout And Fomo) Into Cyanotype Art Creation, Zulfan Ali Mujtaba, Adi Kuntoro
Paradigma: Jurnal Kajian Budaya
The pressure of hustle culture and the Fear of Missing Out (FOMO) in the digital era have triggered an escalation of academic burnout among students, demanding alternative psychological recovery interventions beyond verbal clinical approaches. This research aims to explore the creation of alternative Cyanotype photography as a medium for catharsis and resistance against toxic productivity. Utilizing a Practice-Based Research methodology with an autoethnographic approach, data were extracted from the researcher's subjective experiences and transmuted into a visual artifact titled "Metamorfosis yang Lelah". The cultural studies approach and wabi-sabi aesthetics are specifically applied to analyze visual elements in the Prussian Blue …
Fashion, Lifestyle, And Symbolic Capital: Identity And Resistance In Eka Kurniawan’S Beauty Is A Wound, Dewi Meyrasyawati, Cysakaren Diva Pratiwi, Nisar Ul-Haq
Fashion, Lifestyle, And Symbolic Capital: Identity And Resistance In Eka Kurniawan’S Beauty Is A Wound, Dewi Meyrasyawati, Cysakaren Diva Pratiwi, Nisar Ul-Haq
Paradigma: Jurnal Kajian Budaya
This study examines how fashion culture and lifestyle, understood as modes of self presentation, social performance, and everyday practice, operate as tools of identity construction and resistance in Eka Kurniawan’s Beauty Is a Wound. The objective is to reveal how beauty, personal choices, and public perception function as symbolic capital in negotiating gendered power relations, class hierarchies, and political constraints. Using close textual analysis, the research explores how female characters, particularly Dewi Ayu, mobilize appearance, behavior, and life decisions to challenge dominant ideologies and redefine their roles in society. The findings show that fashion culture in the novel extends beyond …
Predictors Of Complete Obliteration And Favourable Outcome After Single-Modality Treatment For Low-Grade Arteriovenous Malformations: A Multicentre Study, Angelica Fuentes, Salem Tos, Natasha Ironside, Georgios Mantziaris, Yuki Shinya, Basel Musmar, Hamza Adel Salim, Nimer Adeeb, Christopher Ogilvy, Douglas Kondziolka, Ali Alaraj, Min Park, Adam Dmytriw, Hussein Zeineddine, Finn Mccarthy, Hussam Abou-Al-Shaar, Ahmed Abdelsalam, Mustafa Baskaya, Cagdas Ataoglu, Anthony Sanchez-Forteza, Muhammed Amir Essibayi, Abdullah Keles, Sandeep Muram, Howard Riina, Arwin Rezai, Sahin Hanalioglu, Ufuk Erginoglu, Johannes Pöppe, Davide Simonato, Yan-Lin Li, Sandeep Kandregula, Dhairya Lakhani, Christoph Griessenauer, Rahim Abo Kasem, Alejandro Spiotta, Ajit Puri, Jasmeet Singh, Anna Luisa Kuhn, Jan Karl Burkhardt, Robert Starke, Laligam Sekhar, Michael Levitt, David Altschul, Neil Haranhalli, Malia Mcavoy, Paul Foreman, Osama Zaidat, Mohammad Almajali, Hakeem Shakir, Alfred Pokmeng See, Adib Abla, Aashay Patel, Andrew Nguyen, Matthew Koch, Visish Srinivasan, Peng Roc Chen, Spiros Blackburn, Ketan Bulsara, Peter Kan, Louis Kim, Omar Choudhri, Stavropoula Tjoumakaris, Pascal Jabbour, Amey Savardekar, Hugo Cuellar, Michael Lawton, Bharat Guthikonda, Jacques Morcos, Jason Sheehan
Predictors Of Complete Obliteration And Favourable Outcome After Single-Modality Treatment For Low-Grade Arteriovenous Malformations: A Multicentre Study, Angelica Fuentes, Salem Tos, Natasha Ironside, Georgios Mantziaris, Yuki Shinya, Basel Musmar, Hamza Adel Salim, Nimer Adeeb, Christopher Ogilvy, Douglas Kondziolka, Ali Alaraj, Min Park, Adam Dmytriw, Hussein Zeineddine, Finn Mccarthy, Hussam Abou-Al-Shaar, Ahmed Abdelsalam, Mustafa Baskaya, Cagdas Ataoglu, Anthony Sanchez-Forteza, Muhammed Amir Essibayi, Abdullah Keles, Sandeep Muram, Howard Riina, Arwin Rezai, Sahin Hanalioglu, Ufuk Erginoglu, Johannes Pöppe, Davide Simonato, Yan-Lin Li, Sandeep Kandregula, Dhairya Lakhani, Christoph Griessenauer, Rahim Abo Kasem, Alejandro Spiotta, Ajit Puri, Jasmeet Singh, Anna Luisa Kuhn, Jan Karl Burkhardt, Robert Starke, Laligam Sekhar, Michael Levitt, David Altschul, Neil Haranhalli, Malia Mcavoy, Paul Foreman, Osama Zaidat, Mohammad Almajali, Hakeem Shakir, Alfred Pokmeng See, Adib Abla, Aashay Patel, Andrew Nguyen, Matthew Koch, Visish Srinivasan, Peng Roc Chen, Spiros Blackburn, Ketan Bulsara, Peter Kan, Louis Kim, Omar Choudhri, Stavropoula Tjoumakaris, Pascal Jabbour, Amey Savardekar, Hugo Cuellar, Michael Lawton, Bharat Guthikonda, Jacques Morcos, Jason Sheehan
Department of Neurology Faculty Papers
INTRODUCTION: Patient and arteriovenous malformation (AVM) characteristics that portend success after treatment for low-grade brain AVMs remain unknown.
PATIENTS AND METHODS: We utilised the MISTA multicentre registry to identify patients with Spetzler-Martin (SM) grade I or II AVMs treated with stand-alone curative-intent intervention (resection, stereotactic radiosurgery [SRS] or endovascular embolisation). Bivariate and multivariable analyses were performed to identify patient and AVM characteristics predictive of complete obliteration or favourable outcome (complete obliteration without new permanent deficit or post-treatment haemorrhage).
RESULTS: A total of 522 patients were included (292 microsurgery, 152 SRS, 78 embolisation). Complete obliteration rates differed between microsurgery (95.9%), SRS …
Crosstalk Between Upr And Mitochondria: The Triad Of Er-Mitochondria Contacts, Ca²⁺, And Ros, Ester Zito, György Hajnóczky
Crosstalk Between Upr And Mitochondria: The Triad Of Er-Mitochondria Contacts, Ca²⁺, And Ros, Ester Zito, György Hajnóczky
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
Endoplasmic reticulum (ER) stress is triggered by several cellular perturbations causing protein misfolding, and activates the unfolded protein response (UPR), an initially adaptive signaling network that aims to restore ER and cellular homeostasis. Growing evidence indicates that UPR signaling extends beyond ER proteostasis, influencing mitochondrial function and bioenergetics through ER-mitochondria contact sites (ERMCs). The CHOP-ERO1A-IP3R axis has a primary role in recruiting mitochondria to adaptive UPR. However, its sustained activation renders UPR signaling maladaptive, leading to mitochondrial dysfunction through both outer mitochondrial membrane permeabilization (OMMP) and mitochondrial permeability transition pore (mPTP) opening, ultimately contributing to irreversible cell injury and disease …
Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites: Ur-35 Construction Completion Report (Ccr), Pioneer Technical Services, Inc.
Draft Final Butte Priority Soils Operable Unit Unreclaimed Sites: Ur-35 Construction Completion Report (Ccr), Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
The purpose of this Butte Priority Soils Operable Unit (BPSOU) Unreclaimed (UR) Sites Construction Completion Report (CCR) is to describe the tasks completed as described in the Final BPSOU UR Sites: UR-35 Remedial Action Work Plan (RAWP) (referred to herein as RAWP; Atlantic Richfield Company, 2025) (Appendix A). This CCR was prepared to outline Remedial Action (RA) tasks performed at the UR source area, UR-35, within the BPSOU (referred to herein as UR-35 Site or Site) as part of the Further Remedial Elements Scope of Work described in the BPSOU Consent Decree (EPA, 2020). All work was completed according to …
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