Digital Commons Network^™

Phosphate-Mediated Regulation Of Intracellular Calcium Dynamics, Huma Shahzad, Mohammed S. Razzaque

School of Medicine Publications

Phosphate (Pi) and calcium (Ca2+) are essential mineral ions that play coordinated roles in maintaining normal cellular functions. While various steps of calcium signaling are well characterized, emerging evidence suggests the critical role of both intracellular and extra cellular phosphate in regulating intracellular Ca2+. In the cytoplasm, phosphate influences ATP production and organelle calcium buffering and influences the activity of calcium pumps, such as sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA) and the plasma membrane Ca2+-ATPase (PMCA). Extracellular phosphate, taken up via sodium-dependent phosphate transporters, triggers signaling cascades that affect the processes of calcium influx, storage, and release. Additionally, high extracellular phosphate levels …

The Effects Of Cinnamaldehyde On Tetrahymena Thermophila, Sydney Kurland

Publications and Research

In addition to their common use as spices in cooking and baking, cinnamon plants, Cinnamomum zeylanicum and Cinnamomum cassia for example, have long been used in herbal remedies worldwide. Cinnamon contains many vital oils and active compounds including cinnamaldehyde (CMD). Numerous studies looking at potential therapeutic effects of cinnamon have demonstrated its antioxidant, anti-inflammatory, and antimicrobial properties (1, 2, 3).   Therefore, it is important to continue studying the efficacy, benefits, and mechanisms of action of cinnamon and CMD to have a complete understanding of its full potential. Tetrahymena thermophila is a ciliated protozoan commonly used as a model organism to …

Effects Of Recurving Western North Pacific Tropical Cyclones On Downstream Ridges Over Pacific-Western North America, Xiaoyu Bai, Dmitri A. Kalashnikov, Paul Loikith, Siiri Bigalke, Alex Mitchell, Mingfang Ting, Lance F. Bosart, Deepti Singh

Geography Faculty Publications and Presentations

Recurving tropical cyclones (TC) in the Western North Pacific can affect the atmospheric circulation over Pacific‐Western North America (PWNA) via interactions with the midlatitude circulation. Using reanalysis and tropical cyclone best‐track data, we examine how recurving TCs that make extratropical transition modulate 500‐hPa ridge characteristics over PWNA during the peak (June‐September) and late (October–December) seasons. TCs recurving at lower latitudes are associated with more intense and poleward‐centered ridges relative to TCs recurving at higher latitudes, and TCs that recurve farther west are associated with relatively westward‐centered ridges. Characteristics of the prevailing midlatitude flow such as its amplitude and positioning relative …

Foaming Properties And Structural Characterization Of Wheat Germ Albumin-Galacto-Oligosaccharide Covalent Complexes, Zhang Gensheng, Su Wenwen, Huang Xinyu, Du Yinan, Na Zhiguo, Fei Yingmin

Food and Machinery

[Objective] To improve the foaming properties of wheat germ albumin (WGA). [Methods] WGA was modified by wet glycosylation with galacto-oligosaccharides (GOS). The foaming capacity and foam stability of the wheat germ albumin-galacto-oligosaccharide covalent complex (WGA-GOS) were investigated, and its structure was characterized. [Results] Compared with WGA, the foaming capacity and foam stability of the WGA-GOS increased by 41.7% and 7.9%, respectively. Fourier transform infrared spectroscopy, circular dichroism, intrinsic fluorescence spectroscopy, and scanning electron microscopy analyses showed that the introduction of GOS altered the spatial structure of WGA, confirming the formation of covalent bonds between WGA and GOS. After modification, the …

Simulation And Analysis Of Drying Characteristics Of Sorghum In Vibrating Fluidized Bed, Yan Yanqi, Wan Lin, Che Gang, Wang Haochen, Xi You

Food and Machinery

[Objective] To analyze the motion, heat transfer, and mass transfer characteristics of sorghum in a vibrating fluidized bed and determine appropriate vibration and ventilation parameters to achieve efficient drying of sorghum. [Methods] Under the combined action of vibration and hot air, and based on the heat and mass transfer as well as the motion relationships between sorghum particles and the air medium during the fluidized bed drying process, a heat and mass transfer model was developed based on CFD-DEM fluid-solid coupling theory. The effects of vibration frequency, hot air temperature, and apparent wind speed on drying rate and drying unevenness …

Indirect Competitive Enzyme-Linked Immunosorbent Assay For The Detection Of Enrofloxacin Residues In Animal-Derived Food, Huang Jiaxiang, Li Yanfei, Wang Kaile, Zhang Min, Wang Yao, Kang Huaibin

Food and Machinery

[Objective] To establish a highly sensitive indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) for detecting enrofloxacin (ENR) residues in animal-derived food. [Methods] ENR was conjugated with keyhole limpet hemocyanin (KLH) using the carbodiimide method to prepare an immunogen, and New Zealand white rabbits were immunized to produce high-sensitivity antibodies. Based on this, the detection system was optimized to establish ic-ELISA, the detection performance was evaluated, and spiked recovery tests were conducted in animal-derived food. [Results] Under the optimized conditions of coating antigen concentration at 0.25 μg/mL, antibody dilution of 1∶40 000, secondary antibody dilution of 1∶5 000, primary antibody incubation for …

Dilemma Of Food Safety Information Release In The Protection Of Consumer Rights And Interests, Kong Fei

Food and Machinery

From the perspective of consumer rights protection, and in light of the existing institutional mechanisms and practical conditions in the field of food safety, this study finds that the current release of food safety information faces several dilemmas, including insufficient transparency in government food safety information disclosure systems, relatively single channels for information dissemination, and a relatively lagging public opinion monitoring system. In response to these dilemmas, solutions can be proposed from three distinct dimensions. First, enhancing the transparency of the government food safety information release system, namely by clearly defining the responsibilities of various departments and enriching the types …

Determination Of 12 Synthetic Pigments In Wine By Solid Phase Extraction With Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry, Li Xin, Li Bangrui, Chen Dongyang, Zeng Dong, Zuo Jiaxin

Food and Machinery

[Objective] To establish a method for the detection of 12 synthetic pigments in wine by solid-phase extraction/ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). [Methods] After the wine is subjected to purification and enrichment via solid-phase extraction, 12 synthetic pigments are determined using ultra-high performance liquid chromatography for separation and mass spectrometry in multiple reaction monitoring (MRM) mode. The influence of matrix effect on the determination is corrected using a matrix-matched calibration curve. [Results] For the 12 synthetic pigments within the range of 0.2~20 000 μg/L, the peak area has a good linear relationship with their mass concentration, and the coefficient …

Bearing Fault Detection Of Fruit Puree Packing Machine Based On Multi-Channel Depth Residual Graph Neural Network, Yan Shengli, Fu Hui, Li Hao

Food and Machinery

[Objective] To address the issue of bearing failure in fruit puree packaging machines operating in complex work environments. [Methods] This study proposes a method of bearing fault detection of fruit puree packing machine based on multi-channel depth residual graph neural network. First, it uses the Cmor wavelet to complete signal preprocessing, and converts the original one-dimensional bearing fault signal samples into two-dimensional time-frequency graph signals. Second, the study designs the multi-channel feature extraction module, which reduces the number of parameters and enhances the data interaction between each channel, so as to effectively extract the two-dimensional time-frequency spectrum information of the …

Time-Optimal Trajectory Planning For Food Sorting Robotic Arm Based On Improved Fruit Fly Algorithm, Zhang Meijing, Liu Jiacheng, Wang Yang

Food and Machinery

[Objective] To enhance sorting efficiency and motion stability and to address problems in robotic arm trajectory planning in food sorting scenarios, such as long operation time, large joint motion impact, and the tendency of algorithms to fall into local optima. [Methods] Taking the UR 5 six-degree-of-freedom food sorting robotic arm as the research object, a time-optimal trajectory planning method based on an improved fruit fly optimization algorithm (IFOA) was proposed. First, a kinematic model of the robotic arm was established, and its forward and inverse kinematic equations were solved. On this basis, a 3-5-3 piecewise polynomial interpolation method was adopted …

Process Optimization And Phenolic Compound Variation Of Apple-Raspberry Composite Fruit Vinegar During Storage, Zhang Huiming, Jin Tieyan, Li Jiajun

Food and Machinery

[Objective] To analyze the dynamic migration patterns of nutritional components in composite fruit vinegar during storage and thereby reveal the mechanism of storage conditions affecting the quality stability of the fermentation system. [Methods] Single-factor experiments combined with the surface methodology are adopted to optimize the fermentation parameters of apple-raspberry composite fruit vinegar, with the total acid mass concentration employed as the response value. Meanwhile, the composite fruit vinegar prepared by the optimized process is subjected to a 60-day storage test at ambient temperature in the dark. [Results] The optimal brewing parameters for apple-raspberry composite fruit vinegar are as follows:raspberry addition …

Non-Destructive Prediction About Storage Quality Of Prunes In Xinjiang Using Visible And Near-Infrared Spectroscopy Technology, Wen Long, Zhang Hui, Lai Lisi

Food and Machinery

[Objective] To establish a prediction model for the soluble solid content (SSC) and firmness of prunes in Xinjiang using visible and near-infrared (Vis-NIR) spectroscopy, enabling nondestructive and accurate evaluation of the internal quality of the fruit. [Methods] Taking 280 prunes in Xinjiang as research samples, the study collects Vis-NIR reflectance spectra at different storage periods with a near-infrared system. Principal component analysis-Mahalanobis distance (PCA-MD) is applied to eliminate abnormal samples. Then, the remaining dataset is divided into a calibration set and a prediction set at a ratio of 3∶1 using the Kennard-Stone (K-S) algorithm. Partial least squares (PLS) and support …

Construction Of A Quaternary Composite Antimicrobial Film And Its Preservation-Enhancing Effect On Cherry Tomatoes, Nie Longying, Jiao Lijun, Yang Jiamin, Ye Wenbin, Zhu Xiujuan

Food and Machinery

[Objective] To optimize the formula of a chitosan (CS)-carboxymethyl cellulose (CMC) composite film, and to enhance its antimicrobial activity and preservation effect on cherry tomatoes through the incorporation of olive pomace polyphenols (OPP) and curcumin (Cur). [Methods] CS and CMC are used as the matrix, into which OPP and Cur are incorporated. Then, the formula is optimized using response surface methodology, with the inhibition zone diameter against E.coli as the indicator. [Results] The optimal formula is 1.5% CS, 3% CMC, 8% OPP, 3% Cur, 0.9% glycerol, and 1.2% acetic acid, all based on the weight of water. The resulting CS-CMC-OPP-Cur …

Nobiletin Improves Organismal Health By Regulating Circadian Rhythms : Absorption, Mechanisms, And Delivery Strategies, Zhang Mengling, Han Lingxian, Zhao Chan, Liang Zengenni

Food and Machinery

Nobiletin, a hexamethoxyflavone unique to citrus peels, exhibits activity in regulating circadian rhythms. Characterized by a low molecular weight, it can cross the blood-brain barrier and demonstrates various biological functions, including antioxidant, anti-inflammatory, cardiovascular protective, and anticancer effects. However, limitations such as its low water solubility, high crystallinity, and poor stability hinder its nutritional and functional performance in food applications. Therefore, this review summarizes the in vivo absorption of nobiletin, its penetration through the blood-brain barrier, and the biotransformation processes of its active metabolites. Furthermore, this review discusses the regulatory effects on the central clock and peripheral clocks, as well …

Exploration In The Mechanism Of Alcohol Extracts Of Moringa Oleifolia Leaves In Improving Sleep, Gao Wenrong, Liu Weiliang, Zhao Dongmei

Food and Machinery

[Objective] To explore the effect of Moringa oleifera leaves, a characteristic plant resource in Yunnan Province, on the sleep improvement mechanism. [Methods] The chemical composition of ethanol extract from M.oleifera leaves (MOLEE) is determined by targeted metabolomics technology. The efficacy of MOLEE in improving sleep is evaluated in vivo through health food standard assays (mouse autonomous activity monitoring, pentobarbital sodium-induced mouse sleep test, and pentylenetetrazole-induced mouse convulsion test). Network pharmacology, molecular docking, and molecular dynamics simulation are employed in vitro to preliminarily investigate the mechanism of MOLEE on sleep-improving efficacy. [Results] MOLEE is rich in some active ingredients such as …

Structural Characterization, Antioxidant Activity, And Hypoglycemic Effects Of Plantago Seed Polysaccharides, Liu Donglai, Wang Peng, Peng Xinyu, Sha Yixuan, Yin Xingfu

Food and Machinery

[Objective] To investigate the structural characteristics, in vitro antioxidant activity, and hypoglycemic effects of Plantago seed polysaccharides (PSP) on type 2 diabetes mellitus (T2DM) rats. [Methods] The structure of PSP is analyzed via ultraviolet (UV) spectroscopy, high-performance gel permeation chromatography (HPGPC), and ion chromatography (IC). Antioxidant activity is assessed by DPPH, ABTS, and hydroxyl free radical scavenging rates. Then, a T2DM rat model is established using streptozotocin (STZ) to assess the effects of PSP on fasting blood glucose (FBG), blood lipids, and oxidative stress markers. [Results] In an amorphous structure, PSP has a molecular weight of 1. 42×104, primarily composed …

Optimization Of Carotenoid Production From Xinhui Mandarin Juice Fermented By Rhodotorula Mucilaginosa, Liu Minghan, Jian Huali, Zhong Wujie

Food and Machinery

[Objective] To improve the utilization of waste Xinhui mandarin pulp and explore the feasibility of preparing low-cost carotenoid-producing culture media. [Methods] By using Xinhui mandarin juice as the fermentation medium, with the total carotenoid yield and biomass of rhodotorula mucilaginosa as the evaluation indexes, the components of the medium and fermentation conditions were optimized via single-factor experiments and response surface methodology. [Results] The fermentation medium is prepared with Xinhui mandarin juice, with the total sugar content controlled at 95~100 g/L, total nitrogen content at 3 g/L, and initial pH at 6. Under the conditions of 4 mL/ 100 mL inoculum …

Effects Of Thermal Sterilization Conditions On The Aromatic Quality Of Traditional Korean Rice Wine, Xia Weiliang, Jin Tieyan, Xiong Sirui

Food and Machinery

[Objective] To explore the preferred conditions for thermal sterilization of Korean rice wine from the perspective of aroma component preservation. [Methods] The effects of different thermal sterilization conditions on the aroma quality of traditional Korean rice wine are evaluated by combining an electronic nose with headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS). The response values of the electronic nose sensors, as well as the types and content of volatile compounds, are determined. [Results] The response signals of the sensors R7 (inorganic sulfides), R9 (organic sulfides), R2 (nitrogen oxides), R6 (methyls), and R8 (alcohols and aldehydes and ketones) to different heat …

Effect Of Addition Amounts Of Salted Egg White On The Quality Of Fresh Wet Mung Bean Noodles, Tian Caiyun, Chen Lei, Huang Qun, Li Wenjun

Food and Machinery

[Objective] To explore the effect of different addition amounts of salted egg white on the quality and sensory characteristics of noodles, thereby utilizing the rich protein resource in salted egg white. [Methods] Noodles are prepared by incorporating salted egg white at levels of 0, 10%, 20%, 30%, and 40% (w/w, based on flour weight). Then, the noodles are evaluated by protein content, color, rheological properties, texture properties, broken rate, and sensory characteristics. [Results] Salted egg white addition significantly increases the system's protein content. At 20% addition, noodles exhibit optimal comprehensive quality: lowest cooking broken rate (6.7%), best textural properties (hardness, …

Effects Of Key Factors In Hot Air Drying On The Physical Properties Of Ulva Prolifera, Wang Zhen, Yang Jin

Food and Machinery

[Objective] To explore the quality change patterns of Ulva prolifera during the hot air drying process. [Methods] The effects of three key drying factors (hot air temperature, air velocity, and material thickness) on the physical properties of U.prolifera (including moisture content, porosity, specific heat capacity, and thermal conductivity) are systematically investigated. Then, the influence patterns of each factor are clarified by single-factor experiments combined with multi-factor correlation analysis. Finally, a partial least squares regression prediction model is constructed. [Results] An increase in temperature significantly reduces the moisture content, increases porosity and specific heat capacity, while causing a downward trend in …

Effects And Application Strategies Of Tannins In The Regulation Of Red Wine Color And Flavor, Zheng Haiwu, Zhao Xueping, Li Zhengying, Lei Lei, Zhang Meizhi, Xin Shengbing

Food and Machinery

Tannins are among the most important polyphenolic compounds in red wine and play a central role in determining color stability, flavor complexity, and aging potential. This review systematically summarizes the classification, structural characteristics, and the distribution and transformation mechanisms of tannins in red wine. It focuses on the differential effects of soft tannins, hard tannins, and polymerized tannins on the formation and maintenance of wine color, as well as their roles in astringency, bitterness, aroma coordination, and flavor persistence. Furthermore, the applications of tannins in fermentation, aging, and blending are summarized, revealing their important roles in promoting anthocyanin stability, enhancing …

Research Progress On The Preparation Methods And Probiotic Functions Of Postbiotics, Li Junxia, Wang Wei, Si Shufeng, Han Xiaolong, Pan Yulin, Liu Yunguo

Food and Machinery

Postbiotics are non-viable microorganisms and their preparations that are beneficial to the health of the host, mainly including dead cells of microorganisms, cell lysates, and cell metabolites. Systematically introducing the preparation methods of postbiotics, this paper focuses on reviewing their probiotic functional characteristics in maintaining intestinal flora balance, enhancing intestinal epithelial barrier function, enhancing immune regulation, promoting the body's metabolism, and regulating the nervous system. Additionally, this paper makes prospects for future applications of postbiotics in different fields.

Research Advances In The Edible History And Development Prospects Of Hippocampus Abdominalis, Chen Yan, Fan Yufei, Hou Xuemei, Lin Shengnan, Lin Xiangyang

Food and Machinery

Hippocampus abdominalis is one of the commercially cultured seahorse species in the world and is characterized by high fecundity, strong disease resistance, and tolerance to low temperatures. In recent years, the aquaculture of H.abdominalis has rapidly emerged in China, attracting considerable attention to its resource development. To promote the rational development of H.abdominalis and expand its application scenarios, this paper reviews its edible history in China and abroad. For example, it has been included in the food category in South Korea and the Philippines. In addition, its nutritional components, such as proteins and polypeptides, are discussed, revealing that it has …

Tourism Food Quality In Different Transportation Regions Of Henan Province, Nan Qiucai, Li Quangao

Food and Machinery

[Objective] To assess the quality and safety levels of tourism food in different transportation areas of Henan Province. [Methods] Based on publicly available food sampling inspection data from 2023 to 2024, a systematic comparative analysis was conducted on the food quality in three types of areas: highway service areas, railway lines, and areas surrounding scenic spots. Through data cleaning and classification, descriptive statistics were performed by food category and non-conforming items, and the changing trends of sampling results over the two years were compared. [Results] From 2023 to 2024, the overall non-conformity rate of tourism food in Henan Province showed …

Hukum Konstitusi Sebagai Suatu Ilmu, Astim Riyanto

Jurnal Hukum & Pembangunan

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Kebijakan Reklamasi Pantai Dan Laut: Implikasi Terhadap Hak Masyarakat Pesisir Dan Upaya Perlindungannya, Flora Pricilla Kalalo

Jurnal Hukum & Pembangunan

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Larangan Praktek Monopoli Dan Persaingan Usaha Tidak Sehat Pengecuallan· Terhadap Badan Usaha Koperasi, Andjar Pachta Wirana

Jurnal Hukum & Pembangunan

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Menegakkan Hak Asasi Manusia, Menggugat Dlskriminasi, Todung Mulya Lubis

Jurnal Hukum & Pembangunan

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Model Integrasi Lembaga Perwakilan Untuk Pendaftaran Sebagai Alternatif Pendaftaran Untuk Memperoleh Perlindungan Hukum Indikasi Geografis Ubi Cilembu, Tatty A. Ramli, Yeti Sumiyati

Jurnal Hukum & Pembangunan

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Pembalikan Beban Pembuktian Dan Implementasinya Dalam Pemberantasan Tindak Pidana Korupsi Di Indonesia, Marwan Effendy

Jurnal Hukum & Pembangunan

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