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Articles 43771 - 43800 of 5206060
Full-Text Articles in Entire DC Network
Thomas Mann’S Unbound Bodies: A Formal Analysis Of Disease In The Magic Mountain, Julia Shi
Thomas Mann’S Unbound Bodies: A Formal Analysis Of Disease In The Magic Mountain, Julia Shi
Student Theses and Dissertations
My senior thesis argues that disease is a formal element in Thomas Mann’s novel, The Magic Mountain, through the lens of a newly theorized genre: the “Bindungsroman” (“binding-novel”). The scholar Jonas Rosenbrück proposed the Bindungsroman as the successor genre to the Bildungsroman after the latter fell out of public favor after World War I. Whereas the Bildungsroman narrates its hero’s maturation as a process of integration into society, the Bindungsroman’s hero is ontologically unstable and does not achieve normative resolution. This paper examines The Magic Mountain’s protagonist’s development as defined by the doubled play of binding and …
The Purdue Rising Scholars Experience: Exploring Student Success, Robert M. Stwalley Iii, Carol S. Stwalley, Roger Tormoehlen
The Purdue Rising Scholars Experience: Exploring Student Success, Robert M. Stwalley Iii, Carol S. Stwalley, Roger Tormoehlen
Purdue University Press Books
Many intelligent low-socioeconomic status high school students correctly view STEM majors as a way out of poverty, but the challenges to ultimate success are plentiful. For those who applied but did not initially gain admittance into an engineering department, the Rising Scholars program at Purdue University offered these undergraduates a pathway through college that brought them into contact with a network of professional mentors, including university professors, staff, and graduate students. Program participants were also provided opportunities to engage in team-building activities and teaching seminars that involved writing research papers focused on postgraduate careers. Although no longer in operation, the …
Application And Controversy Of "No Penalty For First Violation" Policy In The Field Of Food Safety, Shao Jiang
Application And Controversy Of "No Penalty For First Violation" Policy In The Field Of Food Safety, Shao Jiang
Food and Machinery
After the revision of Article 33 of the Law of the People's Republic of China on Administrative Penalty in 2021 established the "no penalty for first violation" system, its application in the field of food safety has attracted significant attention from both academic and practical communities. This study starts with Article 126 of the Food Safety Law of the People's Republic of China, and combine with the List of Administrative Violations Not Subject to Penalties for First Offenses issued by the State Administration for Market Regulation and local practices, such as Beijing's rule that "expired food is exempt from penalty …
Near-Freezing Point Concentration Of Orange Juice Based On Absorption Membrane Distillation, Ge Sheng, Chen Dong, Liu Jizhou, Cao Xu
Near-Freezing Point Concentration Of Orange Juice Based On Absorption Membrane Distillation, Ge Sheng, Chen Dong, Liu Jizhou, Cao Xu
Food and Machinery
[Objective] Aiming at the issues such as solute loss during the freeze-point concentration of heat-sensitive liquid materials, a near-freezing point concentration device based on absorption membrane distillation is designed and fabricated. The feasibility of the device is verified using orange juice as the research subject. [Methods] A mathematical model of the device is established. Using orange juice as the feed liquid and lithium bromide solution as the absorption solution, this paper calculates and analyzes the variation laws of the concentration rate and energy consumption ratio of concentration with factors such as membrane pore diameter, membrane tube wall thickness, mass concentration …
Effect Of Pepsin Limited Enzymatic Hydrolysis From Wheat Bran Protein On Lipid Lowering In Vitro, Zheng Wenjing, Bai Yang, Liu Cong, Jiri Gala, Wang Jilite, Zhang Yanxia, Li Yuxin
Effect Of Pepsin Limited Enzymatic Hydrolysis From Wheat Bran Protein On Lipid Lowering In Vitro, Zheng Wenjing, Bai Yang, Liu Cong, Jiri Gala, Wang Jilite, Zhang Yanxia, Li Yuxin
Food and Machinery
[Objective] To elucidate the lipid-lowering effect of wheat bran protein from the Hetao region and provide a scientific basis for its deep processing and high-value utilization. [Methods] This paper employs wheat bran protein from the Hetao region as the raw material to prepare pepsin limited enzymatic hydrolysates (P1, P3, P6, and P 12), and investigates their effect on lowering lipid. [Results] Different enzymatic hydrolysates vary in vitro lipid-lowering effects, and the higher mass concentration of samples means a better effect. The cholesterol micelle solubility inhibition rate of 5 mg/mL wheat bran enzymatic hydrolysate P 1 is (45.47±0.36) %, significantly higher …
Vacuum Concentration Process And Antioxidant Activity Of Pressed Walnut Green Husk Juice, Kuerban Gulimire, Chen Kai, Wang Jing, Li Yue
Vacuum Concentration Process And Antioxidant Activity Of Pressed Walnut Green Husk Juice, Kuerban Gulimire, Chen Kai, Wang Jing, Li Yue
Food and Machinery
[Objective] To explore the quality change trend of walnut green husk juice during the concentration process. [Methods] This paper optimizes the concentration process by the single factor combined with response surface tests, and investigates the effects of temperature, time and rotation speed on the mass fractions of polyphenols and polysaccharides. The antioxidant activity of walnut green husk concentrate is detected, and polyphenols in walnut green husk juice are identified and quantitatively analyzed by adopting high performance liquid chromatography (HPLC). [Results] The optimal concentration process of walnut green husk juice is the time of 32 min, temperature of 60 ℃, and …
Artificial Meat 3d Printing Technology And Application Progress, Shi Zhongfen, Yang Zishan, Chen Hongyan, Tian Sumei
Artificial Meat 3d Printing Technology And Application Progress, Shi Zhongfen, Yang Zishan, Chen Hongyan, Tian Sumei
Food and Machinery
With the global population growth and increasing pressure on resources and the environment, traditional meat production methods face severe challenges. In contrast, artificial meat, a sustainable meat substitute, has received widespread attention in recent years. As an additive manufacturing technology for the precision construction of food structures, food 3D printing technology has shown great application potential in artificial meat. This paper reviews the application progress of food 3D printing technology in artificial meat manufacturing, focusing on artificial meat 3D printing technology based on plant protein and cell culture. Additionally, this paper analyzes the challenges faced by food 3D printing technology …
Exploring Bidirectionality In Global Health Partnerships: Perspectives From U.S. Pediatric Residency Programs., Anik Patel, Pauline Kamau, Justus Simba, Ashley Combs, Adelaide Barnes, Kathy Ferrer, Heather Haq, Duncan K. Hau, Lee Morris, Brittany Murray, Amy Rule, Reena P. Tam, Lisa Umphrey, Megan S. Mchenry
Exploring Bidirectionality In Global Health Partnerships: Perspectives From U.S. Pediatric Residency Programs., Anik Patel, Pauline Kamau, Justus Simba, Ashley Combs, Adelaide Barnes, Kathy Ferrer, Heather Haq, Duncan K. Hau, Lee Morris, Brittany Murray, Amy Rule, Reena P. Tam, Lisa Umphrey, Megan S. Mchenry
Manuscripts, Articles, Book Chapters and Other Papers
Introduction Despite growing interest, little guidance exists to re-evaluate global health partnerships (GHPs) through promoting bidirectionality. This study aims to understand the perspectives of United States (U.S.) pediatric global health (GH) faculty on institutional bidirectional practices to inform future discussions with international collaborators. Methods An internally, iteratively developed REDCap-based online survey (REDCap, Vanderbilt University, Nashville, TN), by our diverse author group, collected qualitative data from January 18 to February 20, 2023. Free-text responses were reviewed and coded inductively, with findings framed to generate themes for subsequent engagement with international partners. Results Of the 88 U.S. programs that identify as having …
Postpartum Care, Maternal Knowledge, And Perceptions Of Recommendations For Change, Michelle Embrey
Postpartum Care, Maternal Knowledge, And Perceptions Of Recommendations For Change, Michelle Embrey
Doctor of Nursing Practice Scholarly Project
The purpose of this project was to understand how current postpartum care practices affect women and investigate women’s understanding of current postpartum care practices. This project also sought to investigate recommendations for change in postpartum care practice, women’s knowledge of these recommendations, and how they perceive these changes in relation to their own care. The project was conducted via an anonymous online questionnaire and was distributed through social media. Results showed that most women were favorable to changes recommended by the American College of Obstetricians and Gynecologists and the World Health Organization.
The Highlander Folk School: Incubator For Grassroots Democracy And Its Impacts On The Southern Civil Rights Movement, Kathleen Mcmichael Goodyear
The Highlander Folk School: Incubator For Grassroots Democracy And Its Impacts On The Southern Civil Rights Movement, Kathleen Mcmichael Goodyear
Electronic Theses & Dissertations
Despite the Highlander Folk School’s having played multiple vital roles in the Southern civil rights movement of the 1950s and 1960s, the general public remains unaware of Highlander, which is largely due to its having been omitted from most U.S. history survey course textbooks and ignored by most mainstream historians. These sources perpetuate the image propagated by the 1960s media that the movement was largely composed of Rev. Dr. Martin Luther King, Jr. and his fellow charismatic Black male ministers leading their flock of followers—but the movement was much more than that. Highlander’s rich history in nurturing Southern grassroots activism …
Rhetorical Frames In Daily Fantasy Sports Promotion: Referral-Code Creators And Official Advertisers, Garrett P. Hughes
Rhetorical Frames In Daily Fantasy Sports Promotion: Referral-Code Creators And Official Advertisers, Garrett P. Hughes
Electronic Theses & Dissertations
In the years since the repeal of the Professional and Amateur Sports Protection Act, sports gambling and related products have become increasingly visible in U.S. sports culture. Daily fantasy sports sit within this larger environment and are often promoted as skill-based, social, and routine parts of fandom. This study examined how daily fantasy sports are rhetorically framed on TikTok by comparing official daily fantasy sports advertisements with content posted by referral-code creators, a term used here to describe TikTok users who promote platforms through referral or partner codes while presenting picks, tips, or betting advice. The guiding research question asked …
An Evaluation Of Artificial Intelligence Chatbots As Alternatives To Specialized Software In Teaching Bayesian Pharmacokinetic Analysis, Reza Mehvar
Pharmacy Faculty Articles and Research
Objective
To investigate the accuracy and reliability of artificial intelligence chatbots in estimating pharmacokinetic parameters from limited patient samples and population data for potential application in teaching Bayesian concepts.Methods
Two plasma concentration–time data sets after a single intravenous dose, along with population values for volume of distribution (V) and elimination rate constant (k), were entered into free versions of ChatGPT and Gemini. Three prompts were engineered to assess and improve the accuracy and consistency of patient-only (based on plasma concentrations) and Bayesian (based on plasma concentrations and population data) estimates of V and k. …P300/Cbp Inhibition With Inobrodib In Combination With Gilteritinib And Venetoclax Targets Leukemia Stem Cells In Epigenetic Mutant Aml, Melanie L. Goetz, Jennifer S. Romer-Seibert, Amanda M. Versace, Scott Kogan, Chetan Jeurkar, Robert L. Bowman, Nigel Brooks, Kris Frese, Sara E. Meyer
P300/Cbp Inhibition With Inobrodib In Combination With Gilteritinib And Venetoclax Targets Leukemia Stem Cells In Epigenetic Mutant Aml, Melanie L. Goetz, Jennifer S. Romer-Seibert, Amanda M. Versace, Scott Kogan, Chetan Jeurkar, Robert L. Bowman, Nigel Brooks, Kris Frese, Sara E. Meyer
Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers
Acute myeloid leukemia (AML) is a fatal blood cancer with cytotoxic chemotherapy offering at best 25% 5-year survival. While targeted BCL2 and FLT3 inhibitors venetoclax and gilteritinib are used upfront in the treatment of a subset of adult patients with AML and help to extend the survival of some patients, a curative treatment combination with minimal side effects has yet to be discovered. We find that use of the dual histone acetyltransferase p300/CBP bromodomain inhibitor CCS1477 (inobrodib), together with venetoclax and gilteritinib, virtually eliminates leukemia stem cells in an aggressive preclinical model of DNMT3A/FLT3-mutant AML by impairing pro-oncogenic survival and …
Gut Dysbiosis And Microbial Metabolites In Atopic Dermatitis: Implications For Immune Regulation Along Gut-Skin Axis, Khushbakhat Alia, Hira Khan, Hamna Muzaffar, Nighat Perveen, Sara Alrashedi, Yusra Al Dhaheri, Yasir Waheed, Mohammed Tauqeer Alam, Muhammad Naseem, Khalid Muhammad
Gut Dysbiosis And Microbial Metabolites In Atopic Dermatitis: Implications For Immune Regulation Along Gut-Skin Axis, Khushbakhat Alia, Hira Khan, Hamna Muzaffar, Nighat Perveen, Sara Alrashedi, Yusra Al Dhaheri, Yasir Waheed, Mohammed Tauqeer Alam, Muhammad Naseem, Khalid Muhammad
All Works
Atopic dermatitis (AD) is a multifactorial skin disorder characterized by immune dysregulation, impaired epidermal barrier, and strong microbial imbalance. Although genetic susceptibility and environmental triggers are established AD drivers, growing evidence highlights the gut skin axis as an important but underexplored AD pathogenesis factor. Gut microbiota dysbiosis, loss of short-chain fatty acid (SCFA)-producing bacteria, and altered metabolite profiles, such as tryptophan derivatives and secondary bile acids, have been linked to systemic immune imbalance and skin inflammation. However, the precise mechanism by which gut microbial alterations influence cutaneous immunity remains unclear. This review synthesizes recent advances from clinical and experimental studies …
“We Must Have Jobs!”: The Uaw, Full Employment, And The Drive For Industrial Democracy, Aidan Traverse
“We Must Have Jobs!”: The Uaw, Full Employment, And The Drive For Industrial Democracy, Aidan Traverse
History Honors Theses
Fewer times in American history have been more bleak than the Great Depression. Unemployment rates as high as 20%; people waiting for hours in breadlines to get food for themselves and their families; thousands of Americans living in ramshackle “Hoovervilles.” In the midst of this calamity, the United Auto Workers of America (UAW) proposes full employment economics—a fundamental transformation of American society which would guarantee every American a job. And yet, despite full employment’s popularity in all corners of the US, the policy, somewhat paradoxically, fails. This thesis seeks to explore why.
Neurodiversity Among Nurses: Consequences For Wellbeing And Burnout, Megan Pohlmann
Neurodiversity Among Nurses: Consequences For Wellbeing And Burnout, Megan Pohlmann
WUSM Theses and Dissertations – All Programs
Background/Introduction – Current research highlights three critical aspects of nurse wellbeing: the subjective personal perspective, multifaceted complexity, and variation across individuals. A particular gap in past research is a lack of understanding of how neurodivergence may impact nurses’ workplace wellbeing. Neurodiversity is the variation in human minds and neurocognitive functioning, and neurodivergence is the divergence from what society would consider the norm. Like wellbeing, it is difficult to capture, recognize, and define, which causes confusion among neurodivergent individuals and employers alike. With up to 20% of individuals displaying neurodivergent traits in the workplace, it is important to recognize that those …
Examining The Association Of Nurse Staffing Levels With Delayed Antibiotic And Insulin Administration: A Mixed Methods Study, Mikie Desyana Rachman
Examining The Association Of Nurse Staffing Levels With Delayed Antibiotic And Insulin Administration: A Mixed Methods Study, Mikie Desyana Rachman
WUSM Theses and Dissertations – All Programs
Background: Recent reports indicated that medication errors contributed to 10% of preventable harm among hospitalized patients with over half occurring during the administration stage. Despite emerging research using EHR data to examine care processes and clinical outcomes, limited studies have integrated objective and subjective nursing staffing measures to evaluate how nursing staffing levels could be associated with delays in care delivery.
Method: A parallel convergent mixed-methods study was conducted in four adult medical-surgical units at a Midwestern Academic Medical Center from January 1 – March 31, 2025. Quantitative data of insulin and IV antibiotic administration records, laboratory results, and nurse …
Phase Ii Trial Of Sodium Phenylbutyrate And Taurursodiol In Wolfram Syndrome, Fumihiko Urano, Bess A. Marshall, Stacy Hurst, Amy Robichaux-Viehoever, Saumel Ahmadi, Tamara Hershey, Gregory Van Stavern, Paulina Cruz Bravo, Jennifer Powers Carson, John Pesko, Kelly Fox, Nathalie Erpelding, Camille L Bedrosian
Phase Ii Trial Of Sodium Phenylbutyrate And Taurursodiol In Wolfram Syndrome, Fumihiko Urano, Bess A. Marshall, Stacy Hurst, Amy Robichaux-Viehoever, Saumel Ahmadi, Tamara Hershey, Gregory Van Stavern, Paulina Cruz Bravo, Jennifer Powers Carson, John Pesko, Kelly Fox, Nathalie Erpelding, Camille L Bedrosian
2020-Current year OA Pubs
PB&TURSO was associated with improved or stabilized pancreatic function, vision, and overall symptom burden in individuals with Wolfram syndrome, a rare and progressive degenerative disease.
Evidence-Based Child Development Account Elements And The 530a Account Design, Jin Huang, Michael Sherraden, Lissa Johnson, Margaret Clancy
Evidence-Based Child Development Account Elements And The 530a Account Design, Jin Huang, Michael Sherraden, Lissa Johnson, Margaret Clancy
Center for Social Development Research
Drawing on the 10 evidence-based CDA design elements identified by Sherraden, Clancy, and Beverly, this brief examines the points at which 530A Accounts align with, partially meet, or fall short of the design standards that evidence shows are necessary for a universal and effective children’s account policy.
Hidden In The Mist: Three New Species Of Salamanders Of The Genus Pseudoeurycea (Amphibia: Plethodontidae) From Oaxaca, Mexico, Eduardo A. Aguilar-Herrera, Salomón Sanabria-Urbán, Dulce L. Flores-Martínez, José David Gómez-Tapia, Misael Seba-Chacha, Leopoldo D. Vázquez-Reyes, Francisco A. Rivera-Ortíz, Patricia Ramírez-Bastida, Bruno Cortés-Ortiz, R. Alejandro Calzada-Arciniega, Etienne U. Avila-Ortega Avila-Ortega, Dónovan I. Víquez-Vega, Omar Hernández-Ordoñez, Christopher Blair, Víctor H. Jiménez-Arcos
Hidden In The Mist: Three New Species Of Salamanders Of The Genus Pseudoeurycea (Amphibia: Plethodontidae) From Oaxaca, Mexico, Eduardo A. Aguilar-Herrera, Salomón Sanabria-Urbán, Dulce L. Flores-Martínez, José David Gómez-Tapia, Misael Seba-Chacha, Leopoldo D. Vázquez-Reyes, Francisco A. Rivera-Ortíz, Patricia Ramírez-Bastida, Bruno Cortés-Ortiz, R. Alejandro Calzada-Arciniega, Etienne U. Avila-Ortega Avila-Ortega, Dónovan I. Víquez-Vega, Omar Hernández-Ordoñez, Christopher Blair, Víctor H. Jiménez-Arcos
Publications and Research
We describe three new species of lungless salamanders (Plethodontidae) in the genus Pseudoeurycea from Cerro Rabon, located on the eastern slopes of the Sierra Mazateca, Oaxaca, Mexico. This mid-elevation mountain, largely surrounded by warmer lowlands, remains relatively understudied. We present molecular and morphological evidence distinguishing the three new species from their congeners. According to our phylogenetic analysis, one of the new species belongs to the P. leprosa group, while the other two are members of the P. juarezi group. Notably, one of the new species represents the fourth worm salamander known from west of the Isthmus of Tehuantepec, and another …
Red, Blue, And Bordered: Factors Influencing Immigration Attitudes, Estefania Morales Vilchis
Red, Blue, And Bordered: Factors Influencing Immigration Attitudes, Estefania Morales Vilchis
Political Science Student Papers and Posters
The paper will explore the various social and individual variables that will impact how people perceive immigration as either beneficial to society or a societal threat. Some of the primary variables that will be examined in detail are one’s political affiliation, age, and geographical location; this will address the profound "why" behind our current beliefs on newcomers. The study will particularly address the "Contact Hypothesis" versus "Group Threat Theory" through the lens of how one's personal experiences with immigrants, or lack of, will shape public opinion. The study will focus on the rising psychological issue of "demographic anxiety", specifically, fears …
Hydrodynamic Volatile Escape And Moderately Volatile Isotope Fractionation In Giant Impact Ejecta, Scott D. Hull, Miki Nakajima, Robin M. Canup, Channon Visscher, Paolo A. Sossi
Hydrodynamic Volatile Escape And Moderately Volatile Isotope Fractionation In Giant Impact Ejecta, Scott D. Hull, Miki Nakajima, Robin M. Canup, Channon Visscher, Paolo A. Sossi
Faculty Work Comprehensive List
The Moon and bulk silicate Earth (BSE) are compositionally similar across multiple bulk compositional and isotopic domains, suggesting a common material origin. However, the Moon is strongly depleted in volatile elements and fractionated in heavy moderately volatile element (MVE) isotopes relative to Earth, which is often interpreted to be the result of partial vaporization of the protolunar materials occurring sometime between the giant impact and the crystallization of the lunar magma ocean. Here, we model devolatilization and MVE isotope fractionation due to impact vaporization and partial hydrodynamic escape of a vapor jet in the immediate aftermath of the Earth and …
Subclinical Neuropsychiatric Trait Variation In Parents Of Children With Autism Spectrum Disorder: A Cohort Study, Lindsay J Mullin, Carolyn Lasch, Natasha Marrus, Et Al.
Subclinical Neuropsychiatric Trait Variation In Parents Of Children With Autism Spectrum Disorder: A Cohort Study, Lindsay J Mullin, Carolyn Lasch, Natasha Marrus, Et Al.
2020-Current year OA Pubs
BACKGROUND: Many neuropsychiatric conditions share overlapping features underpinned by shared genetics. In this study, we examined the co-aggregation of sub-threshold variation in neuropsychiatric phenotypes in biological parents of autistic children to provide insights into the intergenerational transmission of genetic liability for autism.
METHODS: Autistic, neuropsychiatric (i.e., anxiety, depression, ADHD), and cognitive traits were characterized in biological parents of children enrolled in a longitudinal developmental study: 189 families of autistic children and 100 families with no autistic children were included. Families were further characterized as having only one (simplex) or more than one (multiplex) autistic child. Maternal and paternal traits were …
Within Melbourne: Landscape, Labor, And Material Culture In A Derbyshire Parish, 1650-1750, Mia Powell
Within Melbourne: Landscape, Labor, And Material Culture In A Derbyshire Parish, 1650-1750, Mia Powell
Senior Honors Papers / Undergraduate Theses
In May of 1695, a group of inhabitants walked the grounds of the English locality of Melbourne (Derbyshire) and collected demographic data from every household within the parish boundaries. From this perambulation came a uniquely detailed census-type listing. Combining that listing with other available sources, including probate records, criminal litigation, property disputes, financial papers, antiquarian accounts, maps, and enclosure agreements from across seven record offices, this project uncovers the complex social and economic developments experienced by those who lived in Melbourne from 1650 to 1750. To analyze this well-documented parish, this thesis utilizes various methodologies. Nominal record linkage connects Melbourne’s …
Longitudinal Changes In Cognition And Brain Imaging In Persons With Human Immunodeficiency Virus, James Kennedy, Sarah A Cooley, June Roman Fox, Kalen J Petersen, Elizabeth Westerhaus, Pat Reid, Linet Lopez, Beau M Ances
Longitudinal Changes In Cognition And Brain Imaging In Persons With Human Immunodeficiency Virus, James Kennedy, Sarah A Cooley, June Roman Fox, Kalen J Petersen, Elizabeth Westerhaus, Pat Reid, Linet Lopez, Beau M Ances
2020-Current year OA Pubs
BACKGROUND: As persons with human immunodeficiency virus (PWH) live longer, interactions between human immunodeficiency virus (HIV), aging, and structural brain integrity become increasingly vital for understanding cognitive disorders. This study analyzed the effects of aging, HIV serostatus, and viral load on cognition and brain volumes in a large cohort of persons without HIV (PWOH), PWH with undetectable virus (PWHU) (HIV RNA ≤50 copies/mL), and PWH with detectable virus (PHWD) (HIV RNA >50 copies/mL). Cross-sectional and longitudinal data were included.
METHODS: Cognitive composites (NPZ4) and brain volumes were obtained from 259 PWOH, 264 PWHU, and 84 PWHD with a total of …
Quantification Of Sarm1 Nadase Activity In Human Peripheral Blood Mononuclear Cells, Lila F Dabill, Ivana R Shen, Jennifer M Brazill, Alicia Neiner, Yo Sasaki, Erica L Scheller
Quantification Of Sarm1 Nadase Activity In Human Peripheral Blood Mononuclear Cells, Lila F Dabill, Ivana R Shen, Jennifer M Brazill, Alicia Neiner, Yo Sasaki, Erica L Scheller
2020-Current year OA Pubs
SARM1 (sterile α and TIR motif-containing protein-1) is an NADase enzyme that serves as the central executioner of Wallerian axon degeneration. Given this, SARM1 is of high interest as a candidate therapeutic target, and SARM1 inhibitors are currently in clinical trials for treatment of neurodegeneration. Beyond neuroscience, emerging studies reveal that SARM1 may also drive aspects of bone fragility, liver pathology, adipose expansion, and insulin resistance in metabolic disease. However, we lack methods to quantify SARM1 activation in humans to better define patients at high risk of SARM1-mediated tissue damage. Unlike neurons, peripheral blood mononuclear cells (PBMCs) represent an easily …
Within These Walls, Nicholas J. Roberts
Within These Walls, Nicholas J. Roberts
LSU Master's Theses
I was raised to understand home through labor. In the working-class household I grew up in, in rural Southeastern Pennsylvania, value was earned through work, identity took shape through trade, and rest was often an afterthought. That framework was not chosen. It was inherited. And it has not been easy to see it clearly from the inside.
The Exhibition, Within These Walls, examines that inheritance through printmaking and sculpture, using the material and spatial language of domestic construction as both subject and method. Through fragile paper structures that resemble wood but cannot hold weight, a staircase that cannot be climbed, …
Short-Term Legume Cover Crops Following Maize Only Marginally Impact Winter Cereals Under Conservation Tillage Management, Arun D. Jani, John E. Erickson, Ramon G. Leon, C. Wesley Wood, Diane Rowland, Heather A. Enloe, Michael J. Mulvaney
Short-Term Legume Cover Crops Following Maize Only Marginally Impact Winter Cereals Under Conservation Tillage Management, Arun D. Jani, John E. Erickson, Ramon G. Leon, C. Wesley Wood, Diane Rowland, Heather A. Enloe, Michael J. Mulvaney
Biology, Agriculture and Chemistry Faculty Publications and Presentations
Context: Warm-season legume cover crops in subtropical environments provide many agroecosystem services but have not been widely adopted because their use usually entails replacing cash crops. Planting short-term legume cover crops following maize (Zea mays L.) to replenish soil nitrogen (N) pools for cool-season cash crops, such as wheat (Triticum aestivum L.), is an innovative approach for integrating legumes into subtropical cereal cropping systems that has not been widely investigated.
Objectives: A maize – legume cover crop – wheat cropping sequence under conservation tillage management was investigated with the following objectives: 1. Evaluate the performance of short-term cowpea [Vigna unguiculata …
Transforming Obesity Management In Primary Care: Shared Medical Appointments (Smas) – An Evidence-Based Practice Project, Glendy Chen
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose/Aims
The purpose of this DNP project is to implement a 10-week Lifestyle Intervention Shared Medical Appointment (LISMA) program in primary care to improve obesity outcomes. Aims include increasing structured visit frequency, enhancing multidisciplinary engagement, and improving metabolic indicators, mindful eating behaviors, and self-efficacy.
Background of Problem & Description of Current Practice
Obesity affects over 40% of U.S. adults and is associated with cardiometabolic morbidity, reduced quality of life, and rising healthcare costs. Guidelines recommend intensive, multicomponent behavioral interventions with frequent contact. Current practice primarily offers one-on-one visits at insufficient frequency with limited team integration, contributing to suboptimal management. LISMAs …
Perspectives On Physical Activity From People With Parkinson’S Disease Who Do Not Engage, Heather Hunter, Jennifer Freeman, Hilary Gunn
Perspectives On Physical Activity From People With Parkinson’S Disease Who Do Not Engage, Heather Hunter, Jennifer Freeman, Hilary Gunn
School of Health Professions
PurposeDespite substantial evidence supporting the benefits of physical activity, People with Parkinson’s disease (pwPD) struggle to remain active. Previous research on physical activity has largely focused on those already engaged. This study aimed to capture the perspectives of pwPD who perceived themselves as inactive.Materials and MethodsConstructivist Grounded Theory was used to explore the beliefs, attitudes, and meaning of physical activity in PwPD who self-identified as inactive. Twenty-one participants consented to participate and were interviewed. Interviews were transcribed verbatim and coded. Data collection and analysis occurred simultaneously, using a constant comparative approach.FindingsFive categories were developed: four that helped explain a lack …