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Articles 41401 - 41430 of 5150228
Full-Text Articles in Entire DC Network
Assessing Young Children's Computational Thinking: Validation Of Items And Item Design Features, And Diagnostic Approaches, Chungsoo Na
All Graduate Theses and Dissertations, Fall 2023 to Present
The goals of this multiple-paper dissertation are to evaluate the psychometric evidence of the Computational and Spatial Thinking Assessment (CaST), designed and developed by the Coding in Kindergarten (CiK) research team (supported by NSF #1842116). In Chapter 2 (Paper 1), I evaluate the psychometric quality of the CaST assessment at the item level. The CaST has moderate item difficulty and high item discrimination, on average, with high reliability and no gender- or age-related item bias. In Chapter 3 (Paper 2), I identify seven item design features from the CaST assessment and examine their impact on item difficulty. All item design …
A Mixed-Methods Investigation Of Physician Compassion In Consultations For Chronic Primary Pain, Sarah Daehler
A Mixed-Methods Investigation Of Physician Compassion In Consultations For Chronic Primary Pain, Sarah Daehler
All Graduate Theses and Dissertations, Fall 2023 to Present
Chronic primary pain refers to physical pain that has no apparent organic cause, cannot be explained by another condition, and has associated psychological distress or functional impairment. Chronic primary pain is common and can significantly interfere with functioning, including occupational or social functioning. Research has shown that physicians struggle to treat this population, with many physicians reporting feeling unequipped and many patients feeling that their physicians are unhelpful and dismissive. Compassion may play a key role in improving these difficult interactions. The present study analyzed a sample of 99 participants with chronic pain and 100 healthy controls to learn more …
Using Picturebooks In Elementary School To Support Discussion, Connection, And Community Action, Polly Parkinson
Using Picturebooks In Elementary School To Support Discussion, Connection, And Community Action, Polly Parkinson
All Graduate Theses and Dissertations, Fall 2023 to Present
Children are in school to acquire knowledge, so the books they read are a significant influence on how they see themselves and others. School curricula often lack diverse voices, which may limit students’ views of themselves and how they relate to their communities. The research objective of this study was to examine the potential for fostering empathy in students, to encourage societal benefits of positive community behaviors, deepen understanding of history, and future contributions to an engaged democratic society.
The problem identified was that although much research exists discussing children’s literature and empathy, little explores whether that empathy leads to …
Freshwater Mussel Reintroduction And Recolonization Habitat Modeling Using Hydraulic, Sediment And Geomorphic Parameters, Megan Elizabeth Dinicola
Freshwater Mussel Reintroduction And Recolonization Habitat Modeling Using Hydraulic, Sediment And Geomorphic Parameters, Megan Elizabeth Dinicola
All Graduate Theses and Dissertations, Fall 2023 to Present
Freshwater mussels are an important group of aquatic animals that live within the riverbed, but their populations have been drastically reduced by habitat alteration and other anthropogenic activities. In an effort to bolster populations, river managers and biologists are using mussel reintroductions as part of their restoration efforts but there are gaps in our understanding of where to reintroduce mussels within a river to see them create self-sustaining populations. This research helps shrink this gap by better understanding the physical habitat needs and population expansion potential of subadult freshwater mussels, or the size of mussel that hatcheries grow for reintroduction, …
Leveraging The Iron Oxide Archive Of Mineralization, Deformation, And Exhumation Across Geologic Time, Jordan L. Jensen
Leveraging The Iron Oxide Archive Of Mineralization, Deformation, And Exhumation Across Geologic Time, Jordan L. Jensen
All Graduate Theses and Dissertations, Fall 2023 to Present
The iron oxide mineral hematite commonly forms from groundwater near Earth’s surface and can preserve a history of fluid flow, fault slip, and landscape evolution. This record can be decoded using (U-Th)/He thermochronology, a dating method based on the temperature-sensitive ingrowth of helium from uranium and thorium decay. Because later heating and natural variation in hematite crystals can produce ambiguous (U-Th)/He results, I integrate dating with tools that reveal differences in hematite chemistry and textures. I apply these techniques to two distinct settings: ancient granitic rocks in Colorado and an active fault zone in the southern San Andreas fault (SSAF) …
Adversarial Heterogeneous Agent Learning For Robotic Systems: A Framework For Coordinated Competitive Behaviors, Christopher T. Allred
Adversarial Heterogeneous Agent Learning For Robotic Systems: A Framework For Coordinated Competitive Behaviors, Christopher T. Allred
All Graduate Theses and Dissertations, Fall 2023 to Present
Autonomous robot teams must move reliably, explain their actions, and work together—even in changing or adversarial settings. We present a structured, three-stage pathway that builds coordinated team behavior from strong single-robot skills. First, we develop robust legged-robot locomotion and interpretability using only internal actuator signals. From these proprioceptive cues, robots learn to classify terrain and predict short-term power use, enabling energy-aware movement without external sensors. We further analyze learned behaviors with motif discovery to reveal recurring sensor–action patterns, which clarify how agility emerges and guide reward design. Second, we compose these skills into heterogeneous teamwork using centralized training with decentralized …
Cultural Adaptation Of A Single Session Acceptance And Commitment Therapy Guide For College Students In Uganda, Miriam Mukasa Kasozi
Cultural Adaptation Of A Single Session Acceptance And Commitment Therapy Guide For College Students In Uganda, Miriam Mukasa Kasozi
All Graduate Theses and Dissertations, Fall 2023 to Present
Mental health problems such as depression, anxiety, and stress are common among Ugandan university students and can make it difficult for them to succeed in school or maintain well-being. However, many students do not have access to professional mental health care. Digital self-help programs can make support more available, especially when they are designed to fit the local culture and context. This project examined how an online program called ACT Guide Lite, which teaches skills from Acceptance and Commitment Therapy (ACT), could be adapted for use with Ugandan college students. Students and other university community members first completed the program …
Investigating Utah's Watershed Restoration Initiative: A Qualitative Case Study Of A State-Managed Collaborative Platform, Casey Trout
All Graduate Theses and Dissertations, Fall 2023 to Present
Collaboration is necessary to address complex, cross-jurisdictional natural resource problems. To better understand the benefits and drawbacks of innovative collaborative structures, this research examined the Utah Watershed Restoration Initiative (WRI). WRI is a state-managed program in Utah that implements cross-boundary habitat restoration projects. Local, state, and federal government agencies as well as non-profit organizations convene on five regional teams to design and evaluate projects. Project partners are engaged at a local level while most program administration occurs at the state level. A case study of WRI was conducted, making use of interviews with 33 participants, document review, and field observations. …
The Dark Side Of Sport: Exploring Conceptualizations And Operationalizations Of Authority Figure-Athlete Abuse, Katherine Nicole Alexander
The Dark Side Of Sport: Exploring Conceptualizations And Operationalizations Of Authority Figure-Athlete Abuse, Katherine Nicole Alexander
All Graduate Theses and Dissertations, Fall 2023 to Present
Although sport can be a fun and positive environment, it can also be a unique and common setting for athlete abuse. Coaches and other authority figures can serve in positive and negative caregiving roles, and many athletes report experiencing at least one form of abuse perpetrated by these important authorities during their sporting careers. We have less research on experiences of abuse in athletes from the United States. The current dissertation was designed to explore ways to more effectively and accurately define and measure athlete abuse perpetrated by authorities and coaches among adults in the United States. Given that there …
Continuous Symmetry Discovery And Enforcement Using Vector Fields With Application To Time Series And Image Data, Benjamin D. Shaw
Continuous Symmetry Discovery And Enforcement Using Vector Fields With Application To Time Series And Image Data, Benjamin D. Shaw
All Graduate Theses and Dissertations, Fall 2023 to Present
Machine learning powers many technologies we use every day, from image classification in computer vision to analyzing time series data such as sensor readings or financial trends. One way to make these systems smarter and more reliable is by using symmetry, meaning patterns that remain unchanged under certain transformations, such as rotations for images or uniform changes in signal amplitude for time series. Discovering these patterns can improve understanding of data and help build models that perform well in new situations.
Current methods for finding symmetry often rely on large neural networks and are limited to simple transformations like stretching …
Counterfactual Explanations For Time Series Through Local Pattern Mining And Generative Models, Omar Bahri
Counterfactual Explanations For Time Series Through Local Pattern Mining And Generative Models, Omar Bahri
All Graduate Theses and Dissertations, Fall 2023 to Present
Machine learning systems increasingly make decisions that affect people’s lives, from medical diagnoses to loan approvals. When these systems analyze time series data—sequences of measurements collected over time, such as heart rhythms or sensor readings—users need to understand why a particular prediction was made. Counterfactual explanations address this need by answering “what-if” questions: what would need to change in the input for the system to make a different prediction?
This dissertation develops methods for generating counterfactual explanations specifically designed for time series data. Time series often contain distinctive local patterns—short subsequences that distinguish one class from another. For example, a …
Impact Of Social Worker Bias On African American Fathers With Open Children Family Services Cases, Jenna Espinosa, Cecil Perry, Jasmine Alvarado, Jennifer Garcia, Lacrietia Grate-Dixson
Impact Of Social Worker Bias On African American Fathers With Open Children Family Services Cases, Jenna Espinosa, Cecil Perry, Jasmine Alvarado, Jennifer Garcia, Lacrietia Grate-Dixson
Electronic Theses, Projects, and Dissertations
Systemic barriers and biases within institutions and policies affect how African American fathers engage with Children and Family Services (CFS). According to research, social worker bias, whether overt or covert, can influence case decision-making, affecting fathers' access to resources and overall involvement in their children’s lives. This study aims to quantitatively assess the impact of social worker bias on African American fathers' engagement by evaluating service completion rates at the .21e hearing. A quantitative research design will be utilized by implementing a validated survey to measure social worker bias and case file reviews to assess service completion. Statistical analyses, including …
Eating Patterns Among College Athletes, Sarah Sanchez
Eating Patterns Among College Athletes, Sarah Sanchez
Electronic Theses, Projects, and Dissertations
The purpose of this cross-sectional study was to examine eating patterns among college athletes attending a minority-serving, urban institution where commuting is highly prevalent to assess potential risks of disordered eating, nutrient deficiencies, and food insecurity. A total of 189 students [M age (SD) = 20.29 + 1.46 years] from a mid-sized university in the U.S. responded to an anonymous online survey. The survey consisted of questions regarding food security, hydration/beverage status, demographics, disordered eating attitudes and behaviors, and food consumption patterns. Findings indicated a low prevalence of severe disordered eating behaviors within this sample. However, attitudes about disordered eating …
Glucagon-Like Peptide-1ra As A Public Health Interventions, Briana Sepeda
Glucagon-Like Peptide-1ra As A Public Health Interventions, Briana Sepeda
Electronic Theses, Projects, and Dissertations
Glucagon-like peptide receptor agonist (GLP-1RA) medications have become a prominent topic of interest both in clinical medicine and broader societal discussions. Although the medication are relatively new and expensive, ongoing research continues to explore pharmacologic modifications aimed at improving therapeutic effectiveness and prolonged drug half-life. GLP-1RAs have gained significant traction due to their ability to lower glycosylated hemoglobin (A1c) and blood glucose levels in individuals who have been diagnosed with type 2 diabetes (T2D). In addition to glycemic control, evidence suggests its associations with appetite suppression, weight loss, reducing cardiovascular disease, improved renal dysfunction, neuroprotective effects related to neurodegenerative disease …
What Is Transitional Care And Its Role In Reducing Readmissions, Decia Rodriguez
What Is Transitional Care And Its Role In Reducing Readmissions, Decia Rodriguez
Electronic Theses, Projects, and Dissertations
Thirty-day readmissions to hospitals creates significant clinical and financial burdens in healthcare systems and worsens patient outcomes. This project reviews transitional care programs as strategic interventions to minimize preventable readmission with a specific focus on pharmacist-led medication reconciliation. Due to the extensive literature review, this work proves that structured transitional care is effective in closing the gaps between acute hospital care and home-based recovery because it coordinates medication management, patient education, and follow-up care. As it has been shown, pharmacists are in a central position to minimize medication errors and enhance compliance, especially in chronic patients such as those with …
Resilience, Stress, And Emotion Regulation In College Students: A Moderated Mediation Model Of Tiktok Engagement, Samuel Bibat, Jon Thang, Hui Zhang, Hannah Carrie, Jessica Golden
Resilience, Stress, And Emotion Regulation In College Students: A Moderated Mediation Model Of Tiktok Engagement, Samuel Bibat, Jon Thang, Hui Zhang, Hannah Carrie, Jessica Golden
Journal of Social, Behavioral, and Health Sciences
This study examined associations between stress, resilience, emotion regulation (ER), and TikTok use. Data were collected from 101 undergraduate students (Mage = 20.04, SDage = 4.02) at a Midwestern private university. Participants completed self-report measures of TikTok use and intensity (i.e., emotional attachment), resilience, perceived stress, and intrapersonal and interpersonal ER. Mediation and moderated mediation analyses were conducted using PROCESS macro models. Stress mediated the relationship between resilience and TikTok use but not intensity. Interpersonal ER moderated the resilience–stress link, with higher interpersonal ER amplifying the negative association between resilience and stress, which in turn was linked …
When The Eagle Strikes The Vein: A Case Of Styloid-Induced Venous Sinus Thrombosis, Neud Kiros, Ahmad Chehab, Abeer Abukamil, Ali Luqman, Kamil Abu-Shaban, Mehdy Haidar, Ay-Ming Wang
When The Eagle Strikes The Vein: A Case Of Styloid-Induced Venous Sinus Thrombosis, Neud Kiros, Ahmad Chehab, Abeer Abukamil, Ali Luqman, Kamil Abu-Shaban, Mehdy Haidar, Ay-Ming Wang
Conference Presentation Abstracts
Clinical History 41-year-old male with no prior relevant medical history presented to the emergency department with severe neck pain and occipital headaches radiating bilaterally to the temporal regions. He also reported diplopia and “tunnel vision.” He had presented two weeks earlier with similar symptoms and was advised outpatient follow-up. Initial CT head and cervical spine were unremarkable. Imaging Findings Brain MRI/MRV demonstrated heterogeneous signal and enhancement in the left transverse and sigmoid sinuses and jugular bulb, initially thought to reflect possible motion artifact. However, CT venography was recommended for further assessment. The MRI also showed subtle left posterior occipital subdural …
Diffuse Marrow And Orbital Fat Signal Abnormality Mimicking Infiltrative Disease: A Case Of "Flip-Flop" On Mri, Mehdy Haidar, Alexander Pietroski, Kamil Abu-Shaban, Anant Krishnan
Diffuse Marrow And Orbital Fat Signal Abnormality Mimicking Infiltrative Disease: A Case Of "Flip-Flop" On Mri, Mehdy Haidar, Alexander Pietroski, Kamil Abu-Shaban, Anant Krishnan
Conference Presentation Abstracts
Clinical History A 68-year-old male with a history of left tonsillar squamous cell carcinoma treated 5 months ago and reportedly negative recent PET and CT scans of the neck and body with eye pain with possible but uncertain remote history of trauma was sent in for imaging of the orbits. The patient has a feeding tube and was recently hospitalized and discharged for tube obstruction. Imaging Findings Orbital imaging revealed diffuse signal alterations involving the orbital and scalp fat, and marrow, characterized by low signal intensity on T1WI and high signal intensity on T2WI. In particular on the STIR sequence, …
Compliance And Systems Data Management Report: Monthly Waiver Participation Trends, May 2026, Tennessee. Department Of Disability And Aging
Compliance And Systems Data Management Report: Monthly Waiver Participation Trends, May 2026, Tennessee. Department Of Disability And Aging
Compliance & System Data/Reports
This monthly report provides data on various aspects of the department's activities and programs.
Postoperative Ileus After Lumbar Spine Surgery: Modifiable Risk Factors And Impact On Outcomes, Ali Mehaidli, Richard Easton, Alqasim Elnaggar, Gary George, Ahmad Almaat, Victor Chang, Jad Khalil, Kevin Taliaferro
Postoperative Ileus After Lumbar Spine Surgery: Modifiable Risk Factors And Impact On Outcomes, Ali Mehaidli, Richard Easton, Alqasim Elnaggar, Gary George, Ahmad Almaat, Victor Chang, Jad Khalil, Kevin Taliaferro
Conference Presentation Abstracts
Introduction: Postoperative ileus (POI) is an infrequent but impactful complication following lumbar spine procedures. While well-characterized in abdominal surgery, spine-specific data remain limited, particularly regarding modifiable risk factors. Materials and Methods: We analyzed 41,164 patients who underwent elective lumbar spine surgery between 2018 and 2023 using the Michigan Spine Surgery Improvement Collaborative (MSSIC) registry. Multivariable generalized estimating equation models were used to identify independent risk factors for POI. We also evaluated the association between POI and postoperative outcomes, including patient-reported outcome measures (PROMs). Results: POI occurred in 1.1% of patients (n = 447). Independent risk factors included older age (RR …
Halo Effect Of Prescribing Guidelines For Opioid Naive Patients Translates To Opioid Non-Naive Patients Undergoing Lumbar Decompression: A Michigan Spine Surgery Improvement Collaborative (Mssic) Study, Anisse Chaker, Geoff Kahn, Michael Melhem, Jian-Hui Hu, Kari Jarabek, Heegook Yeo, Jawad Saad, Abdullah Al-Tekreeti, Kenneth Easton, Jad Khalil, Richard Easton, Doirs Tong, Miguelangelo Perez-Cruet, Noojan Kazemi, Ilyas Aleem, Muwaffak Abulhak, David Nerenz, Victor Chang
Halo Effect Of Prescribing Guidelines For Opioid Naive Patients Translates To Opioid Non-Naive Patients Undergoing Lumbar Decompression: A Michigan Spine Surgery Improvement Collaborative (Mssic) Study, Anisse Chaker, Geoff Kahn, Michael Melhem, Jian-Hui Hu, Kari Jarabek, Heegook Yeo, Jawad Saad, Abdullah Al-Tekreeti, Kenneth Easton, Jad Khalil, Richard Easton, Doirs Tong, Miguelangelo Perez-Cruet, Noojan Kazemi, Ilyas Aleem, Muwaffak Abulhak, David Nerenz, Victor Chang
Conference Presentation Abstracts
Introduction: Chronic opioid dependency in spine surgery is an ongoing concern given the ongoing opioid epidemic. We have previously reported on our cohort of opioid-naıve patients, however the literature has shown that patients with opioid use at baseline are at higher risk of less favorable outcomes. Starting in 2022, MSSIC instituted state-wide prescribing guidelines for opioid naıve patients undergoing one- or two-level lumbar decompression surgery (laminectomy, laminotomy, foraminotomy, microdiscectomy) with performance goals of 80% compliance. The goal of this study was to evaluate whether there would be a form of a “halo” effect on prescribing patterns for patients with baseline …
Persistent Wheezing In An Adolescent Patient, Matilda Dervisevic, Stephen Cliff
Persistent Wheezing In An Adolescent Patient, Matilda Dervisevic, Stephen Cliff
Posters
No abstract provided.
Evaluation And Treatment Of Pediatric Pre-Eruptive Intracoronal Resorption, Sophia Rosen, Robin Onikul, Neena Patel, Jenna Sparks, Amy Burleson
Evaluation And Treatment Of Pediatric Pre-Eruptive Intracoronal Resorption, Sophia Rosen, Robin Onikul, Neena Patel, Jenna Sparks, Amy Burleson
Posters
Pre- eruptive intracoronal resorption (PEIR), also known as “pre-eruptive caries,” is a dental condition characterized by the resorption of dental tissue prior to the eruption of the tooth.1PIER is typically found adjacent to the dentin-enamel junction, within the occlusal dentin of the tooth.2PIER may be referred to as “occult” or hidden caries due to the presence of sound enamel and is often an incidental finding on routine radiographs.3PEIR is often misinterpreted as traditional caries due to its radiographic appearance,3however requires careful evaluation for determination of treatment and long term success. Case report: This case report details a 13 year old …
Self-Directed Violence In Athletes, Adela Vavrinova
Self-Directed Violence In Athletes, Adela Vavrinova
Graduate Theses and Dissertations
Self-directed violence (SDV) in athletes comprises a spectrum of behaviors, including non-suicidal self-injury (NSSI), suicidality, and self-harming behaviors that can be embed- ded within sport contexts. Competitive sport environments may intensify psychological vulnerability through factors such as performance demands, body-image pressures, injury and rehabilitation stress, and norms that discourage help-seeking. This thesis synthesizes existing literature on SDV among athletes with the aim of clarifying how SDV is concep- tualized and measured, summarizing what is known about prevalence patterns, functions, and contextual risk factors, and identifying prevention and intervention strategies relevant to athlete systems. The reviewed evidence suggests the SDV literature …
From Data Digitization To Personalized Care: Deep Learning And Decision Analytics In Healthcare Systems, Ahla Ko
Graduate Theses and Dissertations
This dissertation traces a progression from foundational data infrastructure to individualized clinical decision-making, developing and evaluating three computational frameworks that advance healthcare efficiency and personalization through deep learning and decision analytics. The first study presents an end-to-end pipeline for automated recognition of handwritten medical forms, addressing persistent challenges in health data digitization. Integrating a YOLO-based field detection model, a Convolutional Recurrent Neural Network (CRNN) for text transcription, and a confidence-based human-in-the-loop quality assurance framework, the system achieved 99.75\% Exact Match Accuracy and a 0.13\% Character Error Rate on medical forms collected from a tuberculosis research project in Moldova. A GPU-accelerated …
Assessing The Potential Of Taming Chicken Gut Commensal Bacteria Using Random Transposon Mutagenesis, Arjun Chapagain
Assessing The Potential Of Taming Chicken Gut Commensal Bacteria Using Random Transposon Mutagenesis, Arjun Chapagain
Graduate Theses and Dissertations
The chicken gut microbiome comprises hundreds of bacterial species whose functional roles remain largely unknown, in part because the tools needed to experimentally manipulate these organisms in their native community context have not been systematically developed or validated. This dissertation addresses the gap through three connected research chapters that progressively build a framework for transposon-based genetic delivery in the chicken cecal microbiome, moving from community-wide accessibility mapping to vector optimization to library preparation refinement. In Chapter 2, we established the community-level insertion landscape in chicken cecal metagenome using Himar transposon delivery via RP4 conjugation and aligned Tn-seq reads to a …
Does The Medium Make A Difference? A Quantitative Study Of Traditional Versus Social Media, Erin Elaine Bailey
Does The Medium Make A Difference? A Quantitative Study Of Traditional Versus Social Media, Erin Elaine Bailey
Graduate Theses and Dissertations
People are changing why they use social media, what used to be a way to unwind and stay in touch with old friends is now being used for something much different. This study looks into how young adults (ages 18–25) perceive and retain information from social media compared to traditional media. As social media increasingly functions as both an entertainment and news source, the distinction between it and traditional journalism continues to diminish. Using a quota sample of 300 participants, data were collected through a Qualtrics survey measuring media engagement, usage, perceived credibility, and knowledge retention. Participants were exposed to …
Maternal Low-Sodium Diet Impairs Hippocampal Neurogenesis And Cognition In Adult Mouse Offspring., Xingrao Ke, Connie C. Grobe, Justin L. Grobe, Wei Yu, John J. Reho, Kaela Varberg, Robert H. Lane, Jeffrey L. Segar
Maternal Low-Sodium Diet Impairs Hippocampal Neurogenesis And Cognition In Adult Mouse Offspring., Xingrao Ke, Connie C. Grobe, Justin L. Grobe, Wei Yu, John J. Reho, Kaela Varberg, Robert H. Lane, Jeffrey L. Segar
Manuscripts, Articles, Book Chapters and Other Papers
Sodium (Na) homeostasis is critical for organ and cell function. Although low maternal Na intake during gestation is associated with low offspring survival rates and birth weights, the long-term impact on neurocognitive function is not known. Identifying a relationship between perinatal Na dysregulation and adult behavioral and cognitive outcomes may be important given the prevalence of both dysnatremias and neurocognitive impairment in preterm infants. This study aimed to determine the association between maternal low Na intake (LSI) and hippocampal-dependent behaviors in mice. C57BL/6J dams were fed a standard (0.30%) or low (0.04%) Na diet from postnatal day 0 until postnatal …
Targeted Epigenome Sequencing Of Eosinophils Reveals Cpg Sites And Regulatory Variants Associated With Asthma., Rébecca Dionne-Gagné, Anne-Marie Madore, Anne-Marie Boucher-Lafleur, Tomi Pastinen, Catherine Laprise
Targeted Epigenome Sequencing Of Eosinophils Reveals Cpg Sites And Regulatory Variants Associated With Asthma., Rébecca Dionne-Gagné, Anne-Marie Madore, Anne-Marie Boucher-Lafleur, Tomi Pastinen, Catherine Laprise
Manuscripts, Articles, Book Chapters and Other Papers
Eosinophils are pro-inflammatory cells that play a central role in asthmatic inflammation. However, few studies have examined their methylation profiles in asthma, all relying on microarray-based approaches. Here, an epigenome-wide association study in 183 purified eosinophil samples from the Saguenay-Lac-Saint-Jean asthma family cohort was performed using a custom sequencing panel targeting 4,609,564 CpGs in immune regulatory regions. Two CpG sites in MAEA and SLC9A2 genes, known to be involved in immune function, were significantly associated with asthma, while five additional sites showed suggestive associations. Integration with genotype data (7,829,429 variants) and expression counts (17,513 genes) identified significant quantitative trait loci-mediated …
Leading With Hope: A Clinical Communication Campaign To Promote Partner Hiv Testing In Assisted Partner Notification And Antenatal Care Programs In Uganda., Emily A. Hurley, Violet Gwokyala, Linda Kisaakye Nabitaka, Jolly Beyeza Kashesya, Mercylynn Agasha, Florence Namaganda, Nikolaus Schuetz, J Nalubega Ross, Joseph K B Matovu, Rhoda Wanyenze, Glenn Wagner, Kathy Goggin
Leading With Hope: A Clinical Communication Campaign To Promote Partner Hiv Testing In Assisted Partner Notification And Antenatal Care Programs In Uganda., Emily A. Hurley, Violet Gwokyala, Linda Kisaakye Nabitaka, Jolly Beyeza Kashesya, Mercylynn Agasha, Florence Namaganda, Nikolaus Schuetz, J Nalubega Ross, Joseph K B Matovu, Rhoda Wanyenze, Glenn Wagner, Kathy Goggin
Manuscripts, Articles, Book Chapters and Other Papers
Among heterosexual couples in sub-Saharan Africa, fears of relationship dissolution and inability to bear healthy children following an HIV-positive result remain barriers to HIV testing. Recently expanded availability of pre-exposure prophylaxis (PrEP) affords a critical opportunity to promote HIV testing with reassuring communication that highlights use for relationship preservation and healthy childbearing. We aimed to develop a theoretically-grounded communication intervention to promote partner HIV testing within assisted partner notification (APN) and antenatal care (ANC) programs in Uganda. Through an 18-month iterative co-creation process, we developed the HOPE Clinical Communication Campaign (HOPE-CCC) in collaboration with a project advisory board (PAB) of …