Digital Commons Network^™

Leo: A Carrier To Help Increase Disaster Evacuation Compliance Among Cat Owners, Anna Lorino

Honors Theses

My thesis project is Leo: a carrier to help increase disaster evacuation compliance among cat owners. It’s focused on creating a product that helps increase disaster evacuation compliance among cat owners. There’s an increase in the severity and frequency of natural disasters and being able to evacuate ahead of time saves lives and resources. However, 20-30% of people choose not to evacuate because they don’t want to leave their pet behind. Cats are of particular interest because they are sensitive to environmental stress and need to be contained. The main reasons cat owners fail to evacuate with their cat is …

Quality Measurement Of Blended Learning Model In Higher Education: Scale Development And Validation, Rajeshwari Panigrahi, Khaliq Lubza Nihar, Neha Singh

Higher Learning Research Communications

Objective: This study aimed to develop and test a scale for measuring the quality of blended learning models in higher education.

Methods: This research adopts a sequential mixed-method approach to construct a new measurement scale. The first phase consisted of the inductive approach to identify the items, followed by exploratory factor analysis. The identified dimensions were tested for reliability and validity in the second phase.

Results: The Blended Learning Quality Assessment (BLQA) contains 4 dimensions: Technology Integration, Pedagogy and Curriculum, Physical Infrastructure, and Educator Proficiency. The scale is comprised of 26 items assessing the quality of blended learning programs in …

Analysis Of Self: A Personal And Professional Journey, Lara Overbeck

Dissertations, Theses, and Projects

Abstract

To satisfy graduation requirements, an Analysis of Self paper was completed. The purpose of the analysis of self is to take an in-depth look at how my background and time in the counseling program has shaped and impacted my professional identity. In this paper, I discuss how my time in the counseling program has impacted me, both personally and professionally. I also explore future career goals and identify plans for continued development.

Keywords: Analysis of self, professional identity, growth

Logan Neifert, Saxophone, April 25, 2024 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Factors That Influence African American Millennials’ Knowledge Of Risk Factors For Cardiovascular Disease, Ta'leitheia K. Boutin

Walden Dissertations and Doctoral Studies

Findings have begun to identify that millennials have predispositions that significantly increase their risk of cardiovascular disease (CVD). This quantitative study, grounded in the socioecological model (SEM), addressed a gap of African American millennials' knowledge about CVD risk factors and the relationship of this knowledge to sociodemographic factors. Utilizing Survey Monkey, primary data was obtained through personal connections and social media such as Facebook, and participants were directed to a Heart Disease Knowledge Questionnaire (HDKQ). The requirement to participate was that they had to be African American, born between 1981 and 1996, and reside in Louisiana; the total number of …

Machine Learning-Based Gps Jamming And Spoofing Detection, Alberto Squatrito

Doctoral Dissertations and Master's Theses

The increasing reliance on Global Positioning System (GPS) technology across various sectors has exposed vulnerabilities to malicious attacks, particularly GPS jamming and spoofing. This thesis presents an analysis into detection and mitigation strategies for enhancing the resilience of GPS receivers against jamming and spoofing attacks. The research entails the development of a simulated GPS signal and a receiver model to accurately decode and extract information from simulated GPS signals. The study implements the generation of jammed and spoofed signals to emulate potential threats faced by GPS receivers in practical settings. The core innovation lies in the integration of machine learning …

Celebrating 10 Years Of Apa Accreditation, Carole Woolford-Hunt

Faculty Publications

No abstract provided.

Newsletter, April 2024, Cedar Oaks Guild

Cedar Oaks Guild Newsletter

No abstract provided.

Disordered Clock Protein Interactions And Charge Blocks Turn An Hourglass Into A Persistent Circadian Oscillator, Meaghan S Jankowski, Daniel Griffith, Divya G Shastry, Jacqueline F Pelham, Garrett M Ginell, Joshua Thomas, Pankaj Karande, Alex S Holehouse, Jennifer M Hurley

2020-Current year OA Pubs

Organismal physiology is widely regulated by the molecular circadian clock, a feedback loop composed of protein complexes whose members are enriched in intrinsically disordered regions. These regions can mediate protein-protein interactions via SLiMs, but the contribution of these disordered regions to clock protein interactions had not been elucidated. To determine the functionality of these disordered regions, we applied a synthetic peptide microarray approach to the disordered clock protein FRQ in Neurospora crassa. We identified residues required for FRQ's interaction with its partner protein FRH, the mutation of which demonstrated FRH is necessary for persistent clock oscillations but not repression of …

April 25, 2024, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

April 25, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Statistical Genetic Approaches To Investigate Genotype-By-Environment Interaction: Review And Novel Extension Of Models, Vincent P. Diego, Eron G. Manusov, Marcio Almeida, Sandra Laston, David Ortiz, John Blangero, Sarah Williams-Blangero

School of Medicine Publications

Statistical genetic models of genotype-by-environment (G×E) interaction can be divided into two general classes, one on G×E interaction in response to dichotomous environments (e.g., sex, disease-affection status, or presence/absence of an exposure) and the other in response to continuous environments (e.g., physical activity, nutritional measurements, or continuous socioeconomic measures). Here we develop a novel model to jointly account for dichotomous and continuous environments. We develop the model in terms of a joint genotype-by-sex (for the dichotomous environment) and genotype-by-social determinants of health (SDoH; for the continuous environment). Using this model, we show how a depression variable, as measured by the …

Calafate Zoológicos Humanos, Hans Mülchi Bremer, Latin American And Iberian Institute

LAII Events

Toward the end of the 19th century, 25 people from four different Chilean indigenous groups were kidnapped from Tierra del Fuego and Patagonia by a German businessman and taken to Europe to be exhibited as attractions in cities throughout the continent. THE HUMAN ZOO uncovers the history of this colonial spectacle, and follows the fallout into the present.

With Chilean historian Christian Baez, director Hans Mülchi Bremer contacts these native people’s descendants, and traces their voyage from South America across Europe, paying particular attention to the fate of Calafate, a Selk’nam boy who was taken when he was just 9 …

Vegetation Dieback In The Mississippi River Delta Triggered By Acute Drought And Chronic Relative Sea-Level Rise, James T Cronin

Faculty, Staff and Student Publications

Vegetation dieback and recovery may be dependent on the interplay between infrequent acute disturbances and underlying chronic stresses. Coastal wetlands are vulnerable to the chronic stress of sea-level rise, which may affect their susceptibility to acute disturbance events. Here, we show that a large-scale vegetation dieback in the Mississippi River Delta was precipitated by salt-water incursion during an extreme drought in the summer of 2012 and was most severe in areas exposed to greater flooding. Using 16 years of data (2007-2022) from a coastwide network of monitoring stations, we show that the impacts of the dieback lasted five years and …

Chromosomal 3q Amplicon Encodes Essential Regulators Of Secretory Vesicles That Drive Secretory Addiction In Cancer, Xiaochao Tan, Shike Wang, Guan-Yu Xiao, Chao Wu, Xin Liu, Jiang Yu, Yuanxin Xi, Jing Wang, Kunika Gupta, Apar Pataer, Jack A Roth, Michael P Kim, Fengju Chen, Chad J Creighton, William K Russell, Jonathan M Kurie

Faculty, Staff and Student Publications

Cancer cells exhibit heightened secretory states that drive tumor progression. Here, we identify a chromosome 3q amplicon that serves as a platform for secretory regulation in cancer. The 3q amplicon encodes multiple Golgi-resident proteins, including the scaffold Golgi integral membrane protein 4 (GOLIM4) and the ion channel ATPase Secretory Pathway Ca2+ Transporting 1 (ATP2C1). We show that GOLIM4 recruits ATP2C1 and Golgi phosphoprotein 3 (GOLPH3) to coordinate calcium-dependent cargo loading and Golgi membrane bending and vesicle scission. GOLIM4 depletion disrupts the protein complex, resulting in a secretory blockade that inhibits the progression of 3q-amplified malignancies. In addition to its role …

Role Of Ectopic Olfactory Receptors In The Regulation Of The Cardiovascular-Kidney-Metabolic Axis

Faculty, Staff and Student Publications

Olfactory receptors (ORs) represent one of the largest yet least investigated families of G protein-coupled receptors in mammals. While initially believed to be functionally restricted to the detection and integration of odors at the olfactory epithelium, accumulating evidence points to a critical role for ectopically expressed ORs in the regulation of cellular homeostasis in extranasal tissues. This review aims to summarize the current state of knowledge on the expression and physiological functions of ectopic ORs in the cardiovascular system, kidneys, and primary metabolic organs and emphasizes how altered ectopic OR signaling in those tissues may impact cardiovascular-kidney-metabolic health.

The Center For Teaching And Learning, Anneris Coria-Navia

Faculty Publications

No abstract provided.

Exploring The Coronal Magnetic Field With Galactic Cosmic Rays: The Sun Shadow Observed By Hawc, R Alfaro, C Alvarez, J C. Arteaga-Velázquez, K P. Arunbabu, D Avila Rojas, R Babu, E Belmont-Moreno, K S. Caballero-Mora, T Capistrán, A Carramiñana, S Casanova, P Colín-Farias, U Cotti, J Cotzomi, S Coutiño De León, E De La Fuente, C De León, D Depaoli, R Diaz Hernandez, J C. Díaz-Vélez, M Durocher, M A. Duvernois, K Engel, C Espinoza, K L. Fan, N. Fraija, N. Fraija, J. A. García-González, F. Garfias, A. Gonzalez Muñoz, M. M. González, J. A. Goodman, J. P. Harding, D. Huang, F. Hueyotl-Zahuantitla, A. Iriarte, S. Kaufmann, A. Lara, J. Lee, H. León Vargas, A. L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, J. Martínez-Castro, J. A. Matthews, P. Miranda-Romagnoli, E. Moreno, M. Mostafá, A. Nayerhoda, L. Nellen, T. Niembro, R. Noriega-Papaqui, N. Omodei, E. G. Pérez-Pérez, C. D. Rho, D. Rosa-González, E. Ruiz-Velasco, James M. Ryan, H. Salazar, D. Salazar-Gallegos, A. Sandoval, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Turner, F. Ureña-Mena, E. Varela, L. Villaseñor, X. Wang, I. J. Watson, E. Willox, S. Yun-Cárcamo, H. Zhou

Faculty Publications

Galactic cosmic rays (GCRs) are charged particles that reach the heliosphere almost isotropically in a wide energy range. In the inner heliosphere, the GCR flux is modulated by solar activity so that only energetic GCRs reach the lower layers of the solar atmosphere. In this work, we propose that high-energy GCRs can be used to explore the solar magnetic fields at low coronal altitudes. We used GCR data collected by the High-Altitude Water Cherenkov observatory to construct maps of GCR flux coming from the Sun’s sky direction and studied the observed GCR deficit, known as Sun shadow (SS), over a …

Type 2 Cannabinoid Receptor Expression On Microglial Cells Regulates Neuroinflammation During Graft-Versus-Host Disease, Alison Moe, Aditya Rayasam, Garrett Sauber, Ravi K. Shah, Ashley Doherty, Cheng-Yin Yuan, Aniko Szabo, Bob M. Moore Ii, Marco Colonna, Weiguo Cui, Julian Romero, Anthony E. Zamora, Cecilia J Hillard, William R. Drobyski

2020-Current year OA Pubs

Neuroinflammation is a recognized complication of immunotherapeutic approaches such as immune checkpoint inhibitor treatment, chimeric antigen receptor therapy, and graft versus host disease (GVHD) occurring after allogeneic hematopoietic stem cell transplantation. While T cells and inflammatory cytokines play a role in this process, the precise interplay between the adaptive and innate arms of the immune system that propagates inflammation in the central nervous system remains incompletely understood. Using a murine model of GVHD, we demonstrate that type 2 cannabinoid receptor (CB2R) signaling plays a critical role in the pathophysiology of neuroinflammation. In these studies, we identify that CB2R expression on …

Designing For Deployable, Secure, And Generic Machine Learning Systems, Li-Yun Wang

Dissertations and Theses

Machine learning systems have catalyzed numerous image-centric applications owing to the significant achievements of machine learning algorithms and models. While these systems have showcased the efficacy of machine learning models, certain challenges persist, such as machine learning system design and security vulnerabilities inherent in deep neural networks. Moreover, the deployment of deep neural network models remains a significant hurdle. This dissertation introduces a multimedia prototyping framework tailored for visual analytical applications, improving the reusability of video analysis software tools with minimal performance overhead. Furthermore, we present novel image-processing techniques designed to bolster the robustness of deep neural networks and propose …

Targeting Idh2r140q And Other Neoantigens In Acute Myeloid Leukemia, Paul Shafer, Maksim Mamonkin, Laquisa C Hill, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Norihiro Watanabe, Valentina Hoyos, Premal Lulla, Ann M Leen

Faculty, Staff and Students Publications

For patients with high-risk or relapsed/refractory acute myeloid leukemia (AML), allogeneic stem cell transplantation (allo-HSCT) and the graft-versus-leukemia effect mediated by donor T cells, offer the best chance of long-term remission. However, the concurrent transfer of alloreactive T cells can lead to graft-versus-host disease that is associated with transplant-related morbidity and mortality. Furthermore, ∼60% of patients will ultimately relapse after allo-HSCT, thus, underscoring the need for novel therapeutic strategies that are safe and effective. In this study, we explored the feasibility of immunotherapeutically targeting neoantigens, which arise from recurrent nonsynonymous mutations in AML and thus represent attractive targets because they …

Filming The Invisible: The Hidden Stories Of Indigenous Cultures, Hans Mülchi Bremer, Latin American And Iberian Institute

LAII Events

UNM and CNM (Central New Mexico Community College) are excited to host Filming the Invisible: The Hidden Stories of Indigenous Cultures with Hans Mülchi Bremer. In this presentation Hans will talk about his experience filming hidden stories of Indigenous cultures from the Global South. These stories are often not taught in schools. He will also address how he has had the privilege of accessing these stories with his camera. This documentation has allowed some events to go from anonymity to official history,
Food will be served.

Barriers And Enablers For Externally And Internally Driven Implementation Processes In Healthcare: A Qualitative Cross-Case Study, Terese Johannessen, Ingunn Aase, Berit Ullebust, Line Hurup Thomsen, Elisabeth Holen-Rabbersvik, Lene Schibevaag, David W Bates, Siri Wiig

Faculty, Staff and Students Publications

Background: Quality in healthcare is a subject in need of continuous attention. Quality improvement (QI) programmes with the purpose of increasing service quality are therefore of priority for healthcare leaders and governments. This study explores the implementation process of two different QI programmes, one externally driven implementation and one internally driven, in Norwegian nursing homes and home care services. The aim for the study was to identify enablers and barriers for externally and internally driven implementation processes in nursing homes and homecare services, and furthermore to explore if identified enablers and barriers are different or similar across the different implementation …

Full Issue: Volume 2, Issue 1 - April 2024

Bone Bulletin

i - Editors’ Note by Ari Clements & Amit Syal

ii - Foreword by Dr. Alan Hilibrand

7 - Exploring Approaches to Treatment of Musculoskeletal Injuries by Catherine Alvaro

9 - A Spotlight on the Various Subspecialties of Orthopedic Surgery by Ryan Garemani

14 - Exploring the Importance of Implant Selection in Total Hip Arthroplasty by John Czarnecki

16 - Revolutionizing Orthopaedics: Exploring the Therapeutic Potential of Stem Cells by Harrison Fellheimer

18 - Shoulder Arthroplasty in Patients with Inflammatory Arthritis: Preoperative and Perioperative Management of Disease Modifying Anti-Rheumatic Drug Therapy by Daniel Kwak

22 - The Role of Psychological …

Redefining Recovery: Multimodal Analgesics And Tranexamic Acid In Orthopedic Surgery, Elijah Hoffman

Bone Bulletin

Introduction As the demand for joint replacements continues to rise, optimizing patient outcomes and enhancing recovery have become paramount goals for orthopedic surgeons. Patients used to have minimal mobility following a Total Knee Arthroplasty (TKA) or Total Hip Arthroplasty (THA) due to pain or the effects of sedation from anesthesia. This would lead to longer hospital stays, more complications, and higher opioid use.¹ These surgeries also resulted in levels of blood loss that required transfusion therapy postoperatively.² In recent years, there has been a paradigm shift in postoperative care for total joint arthroplasty (TJA), marked by significant advancements …

A Review Of The Effects Of Early Sport Specialization On The Health Of Adolescent Baseball Players, Robert C. Juniewicz

Bone Bulletin

Introduction

Participation in sports during adolescence is beneficial for participants as it improves fitness, enhances psychosocial development, increases academic performance, and boosts self-esteem.¹ One of the most popular sports among adolescent athletes is baseball, with nearly 500,000 high school players in the United States in 2020.1 While participation in sports has been shown to have clear benefits and has been steadily increasing, recent decades have also seen a dramatic rise in the level of competition.² As a direct result, there has been an increase in the prevalence of early sports specialization (ESS) with an estimated 14-47% of adolescent …

The Ins And Outs Of Wide-Awake Hand Surgery, Molly Milano

Bone Bulletin

Introduction

As the name might imply, “wide awake local anesthesia no tourniquet” (WALANT) is a surgical method to perform hand surgery using only a local anesthetic without the use of a tourniquet or any sedation and general anesthetics. The WALANT technique takes advantage of the vasoconstrictive effects of epinephrine combined with the local anesthetic effects of lidocaine to create a surgical field that does not require a tourniquet or general anesthesia.¹ The main contributor is epinephrine, which decreases bleeding in the surgical field while also lengthening lidocaine’s absorption and effect.² When first introduced to the surgical world, the …

Examining The Role Of Augmented Reality In Total Hip Arthroplasty, Joseph Raphael

Bone Bulletin

Background

In 2023, it was reported that total hip arthroplasty (THA) was the main and effective surgical treatment for advanced hip osteoarthritis, osteonecrosis, and rheumatoid arthritis.¹ As the population ages, the number of annual THA procedures is projected to grow and reach 635,000 by the year 2030.² As such, further improving outcomes in THA will benefit this large population. On average age for individuals who sustain a hip fracture is 80 years old and the lifetime prevalence of hip fractures is 20% in women and 10% in men.³ Fracture reduction and internal fixation or arthroplasty are often …

The Role Of Psychological Readiness In Recovery From Acl Injury In Female Athletes, Samantha Meacock

Bone Bulletin

The Anterior Cruciate Ligament (ACL) injury is common in sports, with female athletes facing a disproportionately higher risk in comparison to male athletes.¹ This susceptibility is the result of a complex relationship between various factors including anatomical, biomechanical, hormonal, neuromuscular, and environmental influences.² In addition, the unique challenges that females face with respect to sports, violence, body image, and family planning create additional stressors that may further contribute to an increased risk for injury.^3,4 Following ACL Reconstruction (ACLR) surgery, these gender discrepancies carry over into recovery as female athletes exhibit decreased rates of return to sport (RTS) …

Shoulder Arthroplasty In Patients With Inflammatory Arthritis: Preoperative And Perioperative Management Of Disease Modifying Anti-Rheumatic Drug Therapy, Daniel Kwak

Bone Bulletin

Introduction

Inflammatory arthritis is a debilitating systemic autoimmune and inflammatory disease that leads to joint damage, resulting in significant pain and disability. Rheumatoid arthritis (RA) is the most common inflammatory arthritis typically associated with advanced arthritic changes of the glenohumeral joint as well as with rotator cuff tears.²⁰ Since the introduction of disease modifying anti-rheumatic drug (DMARD) therapy, patients diagnosed with inflammatory rheumatic diseases have observed improvements in pain management and functional outcomes, alongside a reduction in the occurrence of upper limb arthroplasties.¹⁶ Nonetheless, total joint arthroplasty still remains common in the treatment of RA.^8,14

One recognized …