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Resilience, Self-Efficacy, Openness To Change, And Innovativeness Of Msme Owners: A Quantitative-Qualitative Integration Before, During, And After The Covid-19 Crisis, Imelda T. Angeles Apr 2024

Resilience, Self-Efficacy, Openness To Change, And Innovativeness Of Msme Owners: A Quantitative-Qualitative Integration Before, During, And After The Covid-19 Crisis, Imelda T. Angeles

The South East Asian Journal of Management

Research Aims: Micro, small, and medium-sized enterprises (MSMEs) have consistently demonstrated their resilience in the face of economic challenges, particularly during crises. This study delves into how the experiences of MSMEs before, during, and after the COVID-19 crisis have translated into resilience, self-efficacy, openness to change, and innovativeness as they responded to the unprecedented challenges posed by the pandemic.

Design/Methodology/Approach: This mixed-methods study combines the quantitative analysis of the characteristics of MSME owners with their narratives of their experiences during the COVID-19 crisis, translating adversity into an opportunity.

Research Findings: The integrated results showed how the quantitative-qualitative insights enabled a …


Moving Up Trainees’ Motivation For Using On-Job Training: Relationship Between Leaders’ Support And Trainees’ Motivation For Learning, Azman Ismail, Maryam Jamilah Asha'ari, Siti Nurul Afiqah Foboy, Wan Noordiana Wan Hanafi, Azmawaty Mohamad Nor, Tehsapuan Husin Apr 2024

Moving Up Trainees’ Motivation For Using On-Job Training: Relationship Between Leaders’ Support And Trainees’ Motivation For Learning, Azman Ismail, Maryam Jamilah Asha'ari, Siti Nurul Afiqah Foboy, Wan Noordiana Wan Hanafi, Azmawaty Mohamad Nor, Tehsapuan Husin

The South East Asian Journal of Management

Research Aims: This study examined the relationship between leaders’ support and trainees’ learning outcomes and the relationship between leaders’ support, trainees’ motivation for learning, and trainees’ motivation for using on-job training.

Design/Methodology/Approach: A cross-sectional research design was employed to collect 226 self-report questionnaires from employees at military healthcare organisations in Peninsular Malaysia. The SmartPLS was used to assess the quality of the measurement model and test the structural model.

Research Findings: This study confirmed that trainees’ motivation for learning is an essential mediating construct in the relationship between leaders’ support and trainees’ motivation for using on-job training.

Theoretical Contribution/Originality: This …


Integrity And Legitimacy Of Halal Products: The Urgency Of Halal Supply Chain Management Technology Adoption In Halal Product Authentication Traceability Evidence From Indonesia, Ari Agung Nugroho, Sumiyati Sumiyati, Hamsani Hamsani Apr 2024

Integrity And Legitimacy Of Halal Products: The Urgency Of Halal Supply Chain Management Technology Adoption In Halal Product Authentication Traceability Evidence From Indonesia, Ari Agung Nugroho, Sumiyati Sumiyati, Hamsani Hamsani

The South East Asian Journal of Management

Research Aims: This research aims to determine how technology, integrity, and the environment affect traceability of halal product certification and its relationship with Halal Value Chain (HVSC) Management in micro, small and medium processing industries.

Design/Methodology/Approach: The quantitative research utilised survey data from 285 respondents who are processing industry players throughout Indonesia. Structural Equation Modelling-Partial Least Square (SEM-PLS) is applied for data analysis.

Research Findings: The study's findings indicate that technology adoption and environmental factors have a significant effect on HVSC traceability. The authentication and legitimacy of halal products are positively impacted by technology adoption, among others, which contributes to …


Understanding The Influences Of Hedonic Personality Towards Advertising Avoidance On Social Media, Diera Desmonda, So Yohanes Jimmy, Mohammad Annas Apr 2024

Understanding The Influences Of Hedonic Personality Towards Advertising Avoidance On Social Media, Diera Desmonda, So Yohanes Jimmy, Mohammad Annas

The South East Asian Journal of Management

Research Aims: This study aims to investigate and explore how the hedonic personality that exists in each individual can influence avoidance behaviour towards advertisements on social media platforms.

Design/Methodology/Approach: A quantitative approach with a purposive sampling technique was employed to collect data from 198 respondents who have shopped or at least searched for products on social media. The data were then analysed using the Structural Equation Modelling (SEM) technique.

Research Findings: The results showed that hedonic personality affected advertising avoidance behaviour. Through multigroup analysis, this research found differences in how men and women respond to an advertisement. On the other …


Leadership Styles, Self-Efficacy, And Innovative Work Behaviour Of Software Developers, Win Moe Moe Kyaw, Aye Thanda Soe Apr 2024

Leadership Styles, Self-Efficacy, And Innovative Work Behaviour Of Software Developers, Win Moe Moe Kyaw, Aye Thanda Soe

The South East Asian Journal of Management

Research Aims: The primary aims of this study involve examining the effect of leadership styles on self-efficacy and the effect of self-efficacy on innovative work behaviour.

Design/Methodology/Approach: Quantitative research was conducted by collecting data from 242 randomly selected software developers in four software development companies in Yangon using structured questionnaires. Regression analysis was used to attain the research objectives.

Research Findings: The results showed that transactional and ambidextrous leadership styles have a significant effect on increasing the self-efficacy of software developers. This study also revealed that self-efficacy is an antecedent of the innovative work behaviour of software developers.

Theoretical Contribution/Originality: …


Dronedarone For The Treatment Of Atrial Arrhythmias In Adults With Congenital Heart Disease, Mahdi S Agha, Peter R Ermis, Wayne J Franklin, Dhaval R Parekh, Angeline D Opina, Jeffrey J Kim, Christina Y Miyake, Santiago O Valdes, Wilson W Lam Apr 2024

Dronedarone For The Treatment Of Atrial Arrhythmias In Adults With Congenital Heart Disease, Mahdi S Agha, Peter R Ermis, Wayne J Franklin, Dhaval R Parekh, Angeline D Opina, Jeffrey J Kim, Christina Y Miyake, Santiago O Valdes, Wilson W Lam

The Texas Heart Institute Journal

Background: Atrial tachyarrhythmias are common and difficult to treat in adults with congenital heart disease. Dronedarone has proven effective in patients without congenital heart disease, but data are limited about its use in adults with congenital heart disease of moderate to great complexity.

Methods: A single-center, retrospective chart review of 21 adults with congenital heart disease of moderate to great complexity who were treated with dronedarone for atrial tachyarrhythmias was performed.

Results: The median (IQR) age at dronedarone initiation was 35 (27.5-39) years. Eleven patients (52%) were male. Ten patients (48%) had New York Heart Association class I disease, 10 …


Investigating Turbulence Distribution In The Lower Atmosphere Using Time-Lapse Imagery From A Camera Bank, Benjamin C. Wilson, Santasri R. Bose-Pillai, Jack E. Mccrae, Steven T. Fiorino, Robert P. Freeman, Laura R. Slabaugh Apr 2024

Investigating Turbulence Distribution In The Lower Atmosphere Using Time-Lapse Imagery From A Camera Bank, Benjamin C. Wilson, Santasri R. Bose-Pillai, Jack E. Mccrae, Steven T. Fiorino, Robert P. Freeman, Laura R. Slabaugh

Faculty Publications

The atmosphere’s surface layer (first 50–100 m above the ground) is extremely dynamic and is influenced by surface radiative properties, roughness, and atmospheric stability. Understanding the distribution of turbulence in the surface layer is critical to many applications, such as directed energy and free space optical communications. Several measurement campaigns in the past have relied on weather balloons or sonic detection and ranging (SODAR) to measure turbulence up to the atmospheric boundary layer. However, these campaigns had limited measurements near the surface. We have developed a time-lapse imaging technique to profile atmospheric turbulence from turbulence-induced differential motion or tilts between …


Pml::Rara And Gata2 Proteins Interact Via Dna Templates To Induce Aberrant Self-Renewal In Mouse And Human Hematopoietic Cells, Casey D S Katerndahl, Olivia R S Rogers, Ryan B Day, Ziheng Xu, Nichole M Helton, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley Apr 2024

Pml::Rara And Gata2 Proteins Interact Via Dna Templates To Induce Aberrant Self-Renewal In Mouse And Human Hematopoietic Cells, Casey D S Katerndahl, Olivia R S Rogers, Ryan B Day, Ziheng Xu, Nichole M Helton, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley

2020-Current year OA Pubs

The underlying mechanism(s) by which the PML::RARA fusion protein initiates acute promyelocytic leukemia is not yet clear. We defined the genomic binding sites of PML::RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, using anti-V5-PML::RARA chromatin immunoprecipitation sequencing and CUT&RUN approaches. Most genomic PML::RARA binding sites were found in regions that were already chromatin-accessible (defined by ATAC-seq) in unmanipulated, wild-type promyelocytes, suggesting that these regions are "open" prior to PML::RARA expression. We found that GATA binding motifs, and the direct binding of the chromatin "pioneering factor" GATA2, were significantly enriched near PML::RARA binding sites. Proximity labeling studies …


Accelerating Medicines Partnership® Schizophrenia (Amp® Scz): Rationale And Study Design Of The Largest Global Prospective Cohort Study Of Clinical High Risk For Psychosis, Cassandra M J Wannan, Michael P. Harms, Daneil Mamah, Spero C. Nicholas, Et Al. Apr 2024

Accelerating Medicines Partnership® Schizophrenia (Amp® Scz): Rationale And Study Design Of The Largest Global Prospective Cohort Study Of Clinical High Risk For Psychosis, Cassandra M J Wannan, Michael P. Harms, Daneil Mamah, Spero C. Nicholas, Et Al.

2020-Current year OA Pubs

No abstract provided.


Estate Planning Toolkit - A Beginner's Guide To Estate Planning In Utah, Amanda Christensen, Melanie Jewkes, Andrea Schmutz, Kristilyn Wilkinson, Vincenza Vicari-Bentley, Jerevie Canlas, Alicia Nelson-Bell, Lisa Schainker, Melanie Dabb, Justin Baer, Jared Hawkins Apr 2024

Estate Planning Toolkit - A Beginner's Guide To Estate Planning In Utah, Amanda Christensen, Melanie Jewkes, Andrea Schmutz, Kristilyn Wilkinson, Vincenza Vicari-Bentley, Jerevie Canlas, Alicia Nelson-Bell, Lisa Schainker, Melanie Dabb, Justin Baer, Jared Hawkins

All Current Publications

Normalizing the estate planning conversation can help eliminate emotional distance or fear when discussing important life planning matters. Approaching discussions in a loving and calm manner can bring family closer together and minimize or avoid contention and resentment. Talking about estate planning doesn’t have to be uncomfortable and emotional. Where possible, start conversations early to have a more positive experience, rather than planning at the time of a life crisis. If you have children, start these conversations when they are young to help normalize the process. The Estate Planning Toolkit is a helpful preparation resource that covers wills, trusts, life …


Arkeologi Masuk Sekolah Desa Salenrang (Geopark Maros-Pangkep): Sebuah Wujud Kepedulian Untuk Edukasi Dan Desa Berkelanjutan, Najla Khaulah Safinatunnajah, Regine Balinda, Aqilla Nurriya Apr 2024

Arkeologi Masuk Sekolah Desa Salenrang (Geopark Maros-Pangkep): Sebuah Wujud Kepedulian Untuk Edukasi Dan Desa Berkelanjutan, Najla Khaulah Safinatunnajah, Regine Balinda, Aqilla Nurriya

Bhakti: Jurnal Pengabdian Masyarakat

Arkeologi Masuk Sekolah Desa Salenrang (Maros-Pangkep) merupakan program kepedulian masyarakat Universitas Indonesia (UI) yang bertujuan untuk mengedukasi dan mengetahui potensi bentang alam dan peninggalan arkeologi. Hal tersebut juga bertujuan menumbuhkan sense of belonging terhadap siswa-siswi SD tersebut akan peninggalan nenek moyang mereka. Program dijalankan pada siswa kelas 6 yang berasal dari tiga sekolah, yaitu siswa SDN 221 Inpres Rammang-Rammang, SDN 28 Salenrang, dan SDN 219 Inpres Pannambungan. Metode pengabdian masyarakat yang digunakan adalah perpaduan antara deskripsi kualitatif sebagai pemetaan awal dan participatory action research (PAR) pada implementasi lapangan yang disertai pre-test dan post-test. Melalui evaluasi dari post-test, hasil …


Direct Precipitation Of Siderite In Ferruginous Environments, A Grengs, G Ledesma, Y Xiong, S Katsev, S W. Poulton, E D. Swanner, C Wittkop Apr 2024

Direct Precipitation Of Siderite In Ferruginous Environments, A Grengs, G Ledesma, Y Xiong, S Katsev, S W. Poulton, E D. Swanner, C Wittkop

Faculty Publications

Siderite (FeCO 3 ) is often assumed to precipitate from dissimilatory reduction of Fe-(oxyhydr)oxides, but geochemical and mineralogical analyses from ferruginous (anoxic, Fe-rich) Canyon Lake, USA, suggest Fe-carbonate represents a direct early precipitate unrelated to substantial oxide burial.X-ray absorption near edge structure (XANES) spectroscopy of sediment trap materials and an anoxic sediment core indicated a mixture of Fe(II) and Fe(III) in water column particulates and ferruginous surface sediments, while all Mn phases were reduced.About 60 cm below the sediment-water interface, Fe-Mn carbonates were detected by X-ray diffraction and XANES, while Fe extended X-ray absorption fine structure (EXAFS) spectra were best …


Putting A Slam On Alcohol Violators Through Dram- How The State Of Ohio Can Improve The Day-To-Day Safety Of Its Residents Through Dram Laws, Steven Iwanek Apr 2024

Putting A Slam On Alcohol Violators Through Dram- How The State Of Ohio Can Improve The Day-To-Day Safety Of Its Residents Through Dram Laws, Steven Iwanek

Honors Projects

In the realm of legal frameworks governing the service and consumption of alcohol, Dram Shop Liability Laws play a pivotal role in holding establishments accountable for the consequences of alcohol-related incidents. These laws, known as dram laws, vary across states, delineating the responsibilities of alcohol servers and establishments in preventing the overconsumption of alcohol and the resultant harm. This examination delves into a comprehensive background of dram laws, particularly focusing on their historical evolution, their present implications, and the imperative need for refinement.

As societal dynamics and patterns of alcohol consumption evolve, so too must the legislative mechanisms designed to …


Design A Friendly Nanoscale Chemical Sensor Based On Gold Nanoclusters For Detecting Thiocyanate Ions In Food Industry Applications, Reham Ali, Sayed M Saleh Apr 2024

Design A Friendly Nanoscale Chemical Sensor Based On Gold Nanoclusters For Detecting Thiocyanate Ions In Food Industry Applications, Reham Ali, Sayed M Saleh

Faculty, Staff and Student Publications

The surfactant cetyltrimethylammonium bromide (CTAB) induces the aggregation of gold nanoclusters (GNCs), leading to the development of a proposed fluorometric technique for detecting thiocyanate (SCN-) ions based on an anti-aggregation mechanism. This approach is straightforward to execute, highly sensitive, and selective. A significant quenching effect occurs in fluorescence upon using the aggregation agent CTAB in GNCs synthesis, resulting in a transition from intense red fluorescence to dim red. The decrease in fluorescence intensity of GNCs in the presence of CTAB is caused by the mechanism of fluorescence quenching mediated by aggregation. As the levels of SCN- rise, the fluorescence of …


Financial Hardship And Neighborhood Socioeconomic Disadvantage In Long-Term Childhood Cancer Survivors, Alex J Fauer, Weiyu Qiu, I-Chan Huang, Patricia A Ganz, Jacqueline N Casillas, Gregory T Armstrong, Rebecca Howell, Carrie R Howell, Anne C Kirchhoff, Yutaka Yasui, Paul C Nathan Apr 2024

Financial Hardship And Neighborhood Socioeconomic Disadvantage In Long-Term Childhood Cancer Survivors, Alex J Fauer, Weiyu Qiu, I-Chan Huang, Patricia A Ganz, Jacqueline N Casillas, Gregory T Armstrong, Rebecca Howell, Carrie R Howell, Anne C Kirchhoff, Yutaka Yasui, Paul C Nathan

Faculty, Staff and Student Publications

Background: Long-term survivors of childhood cancer face elevated risk for financial hardship. We evaluate whether childhood cancer survivors live in areas of greater deprivation and the association with self-reported financial hardships.

Methods: We performed a cross-sectional analysis of data from the Childhood Cancer Survivor Study between 1970 and 1999 and self-reported financial information from 2017 to 2019. We measured neighborhood deprivation with the Area Deprivation Index (ADI) based on current zip code. Financial hardship was measured with validated surveys that captured behavioral, material and financial sacrifice, and psychological hardship. Bivariate analyses described neighborhood differences between survivors and siblings. Generalized linear …


Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Magdalena Podkowik, Andrew I Perault, Gregory Putzel, Andrew Pountain, Jisun Kim, Erin E Zwack, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin Apr 2024

Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Magdalena Podkowik, Andrew I Perault, Gregory Putzel, Andrew Pountain, Jisun Kim, Erin E Zwack, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin

Faculty, Staff and Student Publications

The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H2O2, a crucial host defense against S. aureus. We now report that protection by agr surprisingly extends beyond post-exponential growth to the exit from stationary phase when the agr system is no longer turned on. Thus, agr can be considered a constitutive protective factor. Deletion of agr resulted in decreased ATP levels and growth, despite increased rates of respiration or fermentation at appropriate oxygen tensions, suggesting that Δagr cells undergo a shift towards a hyperactive metabolic …


Phase I Trial Of Single-Photon Emission Computed Tomography-Guided Liver-Directed Radiotherapy For Patients With Low Functional Liver Volume, Enoch Chang, Franklin C L Wong, Beth A Chasen, William D Erwin, Prajnan Das, Albert C Koong, Bruce D Minsky, Sonal S Noticewala, Grace L Smith, Cullen M Taniguchi, Maria J Rodriguez, Sam Beddar, Rachael M Martin-Paulpeter, Joshua S Niedzielski, Gabriel O Sawakuchi, Emil Schueler, Luis A Perles, Lianchun Xiao, Janio Szklaruk, Peter C Park, Arvind N Dasari, Ahmed O Kaseb, Bryan K Kee, Sunyoung S Lee, Michael J Overman, Jason A Willis, Robert A Wolff, Ching-Wei D Tzeng, Jean-Nicolas Vauthey, Eugene J Koay Apr 2024

Phase I Trial Of Single-Photon Emission Computed Tomography-Guided Liver-Directed Radiotherapy For Patients With Low Functional Liver Volume, Enoch Chang, Franklin C L Wong, Beth A Chasen, William D Erwin, Prajnan Das, Albert C Koong, Bruce D Minsky, Sonal S Noticewala, Grace L Smith, Cullen M Taniguchi, Maria J Rodriguez, Sam Beddar, Rachael M Martin-Paulpeter, Joshua S Niedzielski, Gabriel O Sawakuchi, Emil Schueler, Luis A Perles, Lianchun Xiao, Janio Szklaruk, Peter C Park, Arvind N Dasari, Ahmed O Kaseb, Bryan K Kee, Sunyoung S Lee, Michael J Overman, Jason A Willis, Robert A Wolff, Ching-Wei D Tzeng, Jean-Nicolas Vauthey, Eugene J Koay

Faculty, Staff and Student Publications

BACKGROUND: Traditional constraints specify that 700 cc of liver should be spared a hepatotoxic dose when delivering liver-directed radiotherapy to reduce the risk of inducing liver failure. We investigated the role of single-photon emission computed tomography (SPECT) to identify and preferentially avoid functional liver during liver-directed radiation treatment planning in patients with preserved liver function but limited functional liver volume after receiving prior hepatotoxic chemotherapy or surgical resection.

METHODS: This phase I trial with a 3 + 3 design evaluated the safety of liver-directed radiotherapy using escalating functional liver radiation dose constraints in patients with liver metastases. Dose-limiting toxicities were …


Pathological Response In Resectable Non-Small Cell Lung Cancer: A Systematic Literature Review And Meta-Analysis, Nathalie A Waser, Melanie Quintana, Bernd Schweikert, Jamie E Chaft, Lindsay Berry, Lien Vo, Joseph Fiore, Donald A Berry, Sarah Goring Apr 2024

Pathological Response In Resectable Non-Small Cell Lung Cancer: A Systematic Literature Review And Meta-Analysis, Nathalie A Waser, Melanie Quintana, Bernd Schweikert, Jamie E Chaft, Lindsay Berry, Lien Vo, Joseph Fiore, Donald A Berry, Sarah Goring

Faculty, Staff and Student Publications

BACKGROUND: Surrogate endpoints for overall survival in patients with resectable non-small cell lung cancer receiving neoadjuvant therapy are needed to provide earlier treatment outcome indicators and accelerate drug approval. This study's main objectives were to investigate the association among pathological complete response, major pathological response, event-free survival and overall survival and to determine whether treatment effects on pathological complete response and event-free survival correlate with treatment effects on overall survival.

METHODS: A comprehensive systematic literature review was conducted to identify neoadjuvant studies in resectable non-small cell lung cancer. Analysis at the patient level using frequentist and Bayesian random effects (hazard …


Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Jisun Kim, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin Apr 2024

Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Jisun Kim, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin

Faculty, Staff and Student Publications

The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H2O2, a crucial host defense against S. aureus. We now report that protection by agr surprisingly extends beyond post-exponential growth to the exit from stationary phase when the agr system is no longer turned on. Thus, agr can be considered a constitutive protective factor. Deletion of agr resulted in decreased ATP levels and growth, despite increased rates of respiration or fermentation at appropriate oxygen tensions, suggesting that Δagr cells undergo a shift towards a hyperactive metabolic …


Study On A Strong Polymer Gel By The Addition Of Micron Graphite Oxide Powder And Its Plugging Of Fracture, Zhonghui Li, Fangping Chen Apr 2024

Study On A Strong Polymer Gel By The Addition Of Micron Graphite Oxide Powder And Its Plugging Of Fracture, Zhonghui Li, Fangping Chen

Faculty, Staff and Student Publications

It is difficult to plug the fracture water channeling of a fractured low-permeability reservoir during water flooding by using the conventional acrylamide polymer gel due to its weak mechanical properties. For this problem, micron graphite powder is added to enhance the comprehensive properties of the acrylamide polymer gel, which can improve the plugging effect of fracture water channeling. The chemical principle of this process is that the hydroxyl and carboxyl groups of the layered micron graphite powder can undergo physicochemical interactions with the amide groups of the polyacrylamide molecule chain. As a rigid structure, the graphite powder can support the …


The Relationship Between Clinical Presentation And The Nature Of Care In Adults With Intellectual Disability And Epilepsy - National Comparative Cohort Study, Sarah Badger, Lance V. Watkins, Paul Bassett, Ashok Roy, Mogbeyiteren Eyeoyibo, Indermeet Sawhney, Kiran Purandare, Laurie Wood, Andrea Pugh, Joanne Hammett, Rory Sheehan, Samuel Tromans, Rohit Shankar Apr 2024

The Relationship Between Clinical Presentation And The Nature Of Care In Adults With Intellectual Disability And Epilepsy - National Comparative Cohort Study, Sarah Badger, Lance V. Watkins, Paul Bassett, Ashok Roy, Mogbeyiteren Eyeoyibo, Indermeet Sawhney, Kiran Purandare, Laurie Wood, Andrea Pugh, Joanne Hammett, Rory Sheehan, Samuel Tromans, Rohit Shankar

Peninsula Medical School

BACKGROUND: A quarter of People with Intellectual Disabilities (PwID) have epilepsy compared with 1% of the general population. Epilepsy in PwID is a bellwether for premature mortality, multimorbidity and polypharmacy. This group depends on their care provider to give relevant information for management, especially epilepsy. There is no research on care status relationship and clinical characteristics of PwID and epilepsy.

AIM: Explore and compare the clinical characteristics of PwID with epilepsy across different care settings.

METHOD: A retrospective multicentre cohort study across England and Wales collected information on seizure characteristics, intellectual disability severity, neurodevelopmental/biological/psychiatric comorbidities, medication including psychotropics/anti-seizure medication, and …


Recurrent Diffuse Alveolar Hemorrhage And Extracorporeal Membrane Oxygenation Utilization In A Hematopoietic Stem Cell Transplant Patient With Hunter's Syndrome., Nasreen Noor, Gene Peir, Asdis Finnsdottir Wagner, Jay Rilinger, Jenna Miller Apr 2024

Recurrent Diffuse Alveolar Hemorrhage And Extracorporeal Membrane Oxygenation Utilization In A Hematopoietic Stem Cell Transplant Patient With Hunter's Syndrome., Nasreen Noor, Gene Peir, Asdis Finnsdottir Wagner, Jay Rilinger, Jenna Miller

Manuscripts, Articles, Book Chapters and Other Papers

We describe the natural history of a three-month-old patient with Hunter Syndrome with hematopoietic stem cell transplant (HSCT) who developed recurrent diffuse alveolar hemorrhage (DAH) requiring extracorporeal membrane oxygenation (ECMO). The patient underwent HSCT with several complications, including veno-occlusive disease and DAH. He was managed with ECMO. Unfortunately, despite initial success he developed recurrent DAH and ultimately died. This is a novel report of this severe adverse event requiring ECMO following the use of HSCT in this rare patient population. We share the clinical strategies employed to address the complications associated with HSCT and the progression of his disease over …


Core Planar Cell Polarity Genes Vangl1 And Vangl2 In Predisposition To Congenital Vertebral Malformations, Yuanqiang Zhang, Sen Zhao, Judith C W Mak, Nao Otomo, Zhengye Zhao, Yuchen Niu, Yoshiro Yonezawa, Guozhuang Li, Mao Lin, Xiaoxin Li, Prudence Wing Hang Cheung, Kexin Xu, Kazuki Takeda, Shengru Wang, Junjie Xie, Toshiaki Kotani, Vanessa N T Choi, You-Qiang Song, Yang Yang, Keith Dip Kei Luk, Kin Shing Lee, Ziquan Li, Pik Shan Li, Connie Y H Leung, Xiaochen Lin, Xiaolu Wang, Guixing Qiu, Disco (Deciphering Disorders Involving Scoliosis And Comorbidities) Study Group, Kota Watanabe, Japanese Early Onset Scoliosis Research Group, Zhihong Wu, Jennifer E Posey, Shiro Ikegawa, James R Lupski, Jason Pui Yin Cheung, Terry Jianguo Zhang, Bo Gao, Nan Wu Apr 2024

Core Planar Cell Polarity Genes Vangl1 And Vangl2 In Predisposition To Congenital Vertebral Malformations, Yuanqiang Zhang, Sen Zhao, Judith C W Mak, Nao Otomo, Zhengye Zhao, Yuchen Niu, Yoshiro Yonezawa, Guozhuang Li, Mao Lin, Xiaoxin Li, Prudence Wing Hang Cheung, Kexin Xu, Kazuki Takeda, Shengru Wang, Junjie Xie, Toshiaki Kotani, Vanessa N T Choi, You-Qiang Song, Yang Yang, Keith Dip Kei Luk, Kin Shing Lee, Ziquan Li, Pik Shan Li, Connie Y H Leung, Xiaochen Lin, Xiaolu Wang, Guixing Qiu, Disco (Deciphering Disorders Involving Scoliosis And Comorbidities) Study Group, Kota Watanabe, Japanese Early Onset Scoliosis Research Group, Zhihong Wu, Jennifer E Posey, Shiro Ikegawa, James R Lupski, Jason Pui Yin Cheung, Terry Jianguo Zhang, Bo Gao, Nan Wu

Faculty, Staff and Students Publications

Congenital scoliosis (CS) is the most common congenital spinal disorder caused by congenital vertebral malformations (CVMs), influenced by genetic and environmental factors and exhibiting diverse clinical presentations. Here, we identified the critical roles of Vangl1 and Vangl2, two core components in the Wnt/planar cell polarity (Wnt/PCP) signaling pathway, in vertebral development and in predisposition to CVMs in CS patients. We found that in Vangl mutant mouse models, the CVMs present in a Vangl gene dose- and gestational hypoxia-dependent manner. Our studies reveal a complex etiology of CS and its association with Wnt/PCP signaling.


Expanding Youth-Friendly Hiv Self-Testing Services During The Covid-19 Pandemic: Qualitative Analysis Of A Crowdsourcing Open Call In Nigeria, Onyekachukwu Anikamadu, Oliver Ezechi, Alexis Engelhart, Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Ponmile Ogunjemite, Babatunde Ismail Bale, Daniel Nwachukwu, Titilola Gbaja-Biamila, David Oladele, Adesola Z Musa, Stacey Mason, Temitope Ojo, Joseph Tucker, Juliet Iwelunmor Apr 2024

Expanding Youth-Friendly Hiv Self-Testing Services During The Covid-19 Pandemic: Qualitative Analysis Of A Crowdsourcing Open Call In Nigeria, Onyekachukwu Anikamadu, Oliver Ezechi, Alexis Engelhart, Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Ponmile Ogunjemite, Babatunde Ismail Bale, Daniel Nwachukwu, Titilola Gbaja-Biamila, David Oladele, Adesola Z Musa, Stacey Mason, Temitope Ojo, Joseph Tucker, Juliet Iwelunmor

2020-Current year OA Pubs

BACKGROUND: HIV self-testing (HIVST) among young people is an effective approach to enhance the uptake of HIV testing recommended by the World Health Organization. However, the COVID-19 pandemic disrupted conventional facility-based HIV testing services, necessitating the exploration of innovative strategies for the effective delivery of HIVST.

OBJECTIVE: This study analyzed the outcomes of a digital World AIDS Day crowdsourcing open call, designed to elicit youth responses on innovative approaches to promote HIVST among young people (14-24 years) in Nigeria during COVID-19 restrictions.

METHODS: From November 2 to 22, 2020, a World AIDS Day 2020 crowdsourcing open call was held digitally …


The Effects Of Academic Counseling On Undergraduate Student Degree Completion At A Northwestern State University, James Mccuistion Apr 2024

The Effects Of Academic Counseling On Undergraduate Student Degree Completion At A Northwestern State University, James Mccuistion

Walden Dissertations and Doctoral Studies

The problem that was addressed through this study is the declining student degree completion rate for a public state baccalaureate institution in a northwestern state over the six-year period of 2014 to 2020. The purpose of this quantitative study was to determine if completion of an undergraduate degree within six years could be predicted by the number of advising sessions a student had during degree completion. A student retention model created by Amara Atif, Deborah Richards, & Ayse Bilgin and NACADA’s academic advising core competencies model served as the framework, where student-institutional interactions through best practices in academic counseling can …


An Effective, Robust, And Strategic Succession Plan For A Primary Law Enforcement Agency In Guyana, South America, Nicola Denise Kendall Apr 2024

An Effective, Robust, And Strategic Succession Plan For A Primary Law Enforcement Agency In Guyana, South America, Nicola Denise Kendall

Walden Dissertations and Doctoral Studies

The client organization, Guyana’s principal law enforcement agency, lacked a robust, effective, and strategic succession plan to fill vacancies for senior leadership and management. The current qualitative case study was to ascertain the appropriate strategies that could be employed for this organization, and by extension public organizations and law enforcement agencies, to have a robust, effective, and strategic succession plan. The conceptual framework was based on the succession planning model, which focused on key concepts such as strategy, knowledge management, talent management, organizational culture, leadership development, and management commitment. Data were collected from interviews, with 23 participants and a review …


Strategies Employed By School Social Workers In Virginia To Help Children Cope With Parental Death, Jamitta Covington Apr 2024

Strategies Employed By School Social Workers In Virginia To Help Children Cope With Parental Death, Jamitta Covington

Walden Dissertations and Doctoral Studies

Research has indicated that school social workers employ a variety of strategies or interventions that affect the child’s adjustment in school. The psychological, physical, and social issues impacting children after the death of a parent can have long term effects on their development. However, there is a lack of knowledge regarding strategies that provide support for children’s adjustment to the grief process following a parent’s death. The purpose of this generic qualitative study was to identify strategies to improve, enhance, and contribute to social work practice. The study was guided by Kubler-Ross’s grief theory, ecological systems theory, and assumptions of …


Using Nurse-Assisted Telemedicine To Reduce Healthcare System Utilization By Rural Congestive Heart Failure Patients, Melissa Diehl Weidner Apr 2024

Using Nurse-Assisted Telemedicine To Reduce Healthcare System Utilization By Rural Congestive Heart Failure Patients, Melissa Diehl Weidner

Walden Dissertations and Doctoral Studies

Congestive heart failure (CHF) is among the most common reasons for emergency room utilization and hospitalizations in those over age 65. With the rapidly aging population in the United States, the number of CHF patients is projected to continue to rise, disproportionately affecting rural communities. This research study evaluated an innovative nurse-led telemedicine program developed by one rural healthcare system to address the care and economic influence of rural CHF care. The purpose of this causal comparative analysis was to determine the impact a nurse-assisted telemedicine program had on the number of emergency room visits and hospital admissions for CHF …


Validity And Reliability Of Self-Concept Instrument Using Rasch Model, Meyliani Latifah, Ipah Saripah, Dodi Suryana, Yaya Sunarya Apr 2024

Validity And Reliability Of Self-Concept Instrument Using Rasch Model, Meyliani Latifah, Ipah Saripah, Dodi Suryana, Yaya Sunarya

Jurnal Kajian Bimbingan dan Konseling

The development of instruments designed to assess student self-concept is crucial. This understanding of self-concept is based on the premise that it is a dynamic and ever-evolving construct. The concept of self-concept is initially conceived as a unidimensional structure but subsequently evolves into a multidimensional construct. The present study assesses the validity and reliability of the newly developed self-concept instrument. In Indonesia, there is a paucity of research that employs the Rasch Model to examine self-concept instruments, particularly in the context of the junior high school population. The objective of this study was to analyze the self-concept instrument using the …


Cultural Intelligence Profile Of Junior High School Counsellors And Its Implication On Multicultural Counseling, M Ramli, Nur Mega Aris Saputra, Ulfah Muhayani Apr 2024

Cultural Intelligence Profile Of Junior High School Counsellors And Its Implication On Multicultural Counseling, M Ramli, Nur Mega Aris Saputra, Ulfah Muhayani

Jurnal Kajian Bimbingan dan Konseling

The diversity of ethnicities, religions, and races that exist in Indonesia contribute to the country's characterization as a nation with a multitude of cultures. In the context of the relationship between counselor and counselee, cultural diversity is a significant concern. The comprehension, awareness, and work behavior of the counselee's cultural diversity is indicative of the counselor's cultural intelligence. The concept of cultural intelligence is a crucial aspect that counselors must consider when providing multicultural counseling services. The objectives of this research are to determine the description of counselors' cultural intelligence and its application in multicultural counseling. The research employed a …