Digital Commons Network^™

A 2-Year Randomized Trial Of Pitavastatin Calcium Vs Placebo To Treat Combined Dyslipidemia In Adolescents With Overweight And Obesity., Brian W. Mccrindle, Silva Arslanian, Michele Mietus-Snyder, Elaine M. Urbina, Adam L. Ware, Jessica E. Teng, Felicia Trachtenberg, Mark W. Russell, Amy S. Shah, Mark Cartoski, Julie A. Brothers, Christine San Giovanni, Justin P. Zachariah, Sandra Pena, William T. Mahle, Amy L. Peterson, Sheela N. Magge, Geetha Raghuveer, Binu Sharma, Valiantsina Kazlova, Craig A. Sponseller, D'Andrea Freemon, Mario Stylianou, Sarah D. De Ferranti, Pediatric Heart Network Investigators

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Combined dyslipidemia of overweight/obesity (CDO) is prevalent in youth and is associated with an increased risk of early cardiovascular disease.

OBJECTIVE: We sought to determine the impact and safety of statin therapy for CDO in adolescents.

METHODS: A double-blind, randomized trial was performed across 18 North American sites. Participants aged 10 to 19 years with body mass index ≥85th percentile and CDO defined as non-high-density lipoprotein cholesterol (non-HDL-C) ≥120 mg/dL (3.10 mmol/L) and either low HDL-C or high triglyceride:HDL-C ratio were randomized centrally to receive either pitavastatin calcium 4 mg/d or placebo for 2 years. The primary outcome was …

Birth-Size Reference Charts For Newborns Admitted To The Neonatal Intensive Care Units., Fu-Sheng Chou, Hung-Wen Yeh, Crystal Hsueh, Irene E. Olsen, Veeral N. Tolia, Reese H. Clark

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Our original birth-size reference charts (the Olsen charts), published in 2010 (weight, length, head circumference) and 2015 (body mass index), had limitations, including manually defined exclusion criteria and the use of completed gestational weeks. This project aimed to update the charts and address those limitations.

METHODS: We analyzed de-identified data from infants admitted to Pediatrix NICUs between 2010 and 2022. In contrast to prior work, newborns with mortality before discharge, multiple births, and congenital anomalies were included; only statistical outliers (defined as two times the interquartile range below the first quartile or above the third quartile) were excluded. Gestational …

What Sustainability Disclosures Disclose, Kim Hajin

Coase-Sandor Institute for Law & Economics Research Paper Series

Sustainability disclosures are the backbone of corporate sustainability efforts. If stakeholders want companies to compete over how “good” they are for society, they need a way to see what companies are doing and trying to do. But these disclosures have been widely criticized for their lack of credibility and comparability. To improve them, nonprofits and companies have developed voluntary reporting frameworks that many firms have now adopted and that have informed mandatory disclosure regulations. These critiques and regulatory debates have proceeded, however, without basic facts about what these disclosures contain and whether voluntary tools help. Answering these questions has been …

Cancer In Tennessee, 2017-2021, Tennessee. Department Of Health.

Cancer in Tennessee

No abstract provided.

Lymph Node Dissection And Postoperative Complications After Lung Cancer Resection, Isheeta Madeka, Khaled Noueihed, Jacob Woodroof, Shale Mack, Hamza Rshaidat, Gregory L Whitehorn, Sneha Alaparthi, Scott H. Koeneman, Tyler R. Grenda, Nathaniel R. Evans, Iii, Olugbenga T. Okusanya

Department of Surgery Faculty Papers

Importance: Current lung cancer guidelines recommend lymph node sampling (LNS) with the 3 + 1 rule, which recommends station-based sampling with at least 3 N2 (mediastinal) and 1 N1 (hilar) nodal stations. Although there is oncologic benefit to rigorous LNS, potential negative impacts on surgical outcomes have not been well investigated. As adoption of the 3 + 1 rule increases given its formalization as guideline-concordant care, associations with adverse outcomes are crucial to characterize.

Objective: To evaluate whether satisfying the 3 + 1 rule is associated with increased postoperative complications.

Design, setting, and participants: This retrospective cohort study used the …

Incidence And Risk Factors For Stillbirth In Kenya, Mozambique And The Gambia: The Precise Cohort Study, Grace Mwashigadi, Joseph Akuze, Angela Koech, Hawanatu Jah, Anna Roca, Geoffrey Omuse, Moses Mukhanya, Marleen Temmerman, Amina Abubakar, Patricia Okiro

Centre of Excellence in Women and Child Health

Background

Methods

Terminal Digit Preference And Threshold Avoidance In Digital Blood Pressure Measurements During Pregnancy: Secondary Analysis Of Data From The Clip And Precise Cohorts, Peter Dadelszen, Akshdeep Sandhu, Jeffrey Bone, Rahat Qureshi, Olukayode Dada, Ashalata Mallapur, Marleen Temmerman, Marie-Laure Volvert, Joseph Waiswa, Moses Mukhanya, Angela Koech

Centre of Excellence in Women and Child Health

Background:Screening for, detecting, and managing pregnancy hypertension is a core function of antenatal care. To reduce both training requirements and the risks of measurement error in blood pressure (BP) values, automated and semiautomated BP devices have been validated in pregnant women with normal BP and pregnant women with hypertension and introduced for serial antenatal measurement of BP.

Objectives:The study aimed to (1) determine whether or not repeated BP measurements reduced the presence of terminal digit preference and (2) discern whether or not there was evidence of threshold avoidance in the Community-Level Interventions for Preeclampsia (CLIP) trials compared with …

Partial Insect-Based Meal Inclusion In The Diets Of Ross® 308 Broilers Upregulates Growth And Immune Related Genes, Victor K. Rotich, Isaac M. Osuga, Mathew G. Gicheha, Shaphan Y. Chia, Jandouwe Villinger, Anderson N. Maina, Jinhua Xiao, Dennis Beesigamukama, Chrysantus M. Tanga

All Peer-Reviewed Publications

This work investigated the effects of black soldier fly ( Hermetia illucens L.) larvae meal (BSFLM) on growth- and immune-related gene expression in Ross 308 broilers. Birds were fed diets containing soybean meal (SBM), fishmeal (FM), combinations with BSFLM, or BSFLM alone. Growth, organ weights, immune genes [interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrotic factor alpha (TNF-α), interferon-gamma (IFN-γ)] and growth-related genes [chicken growth hormone (cGH), insulin growth factor 1 (IGF-1)] expression were measured. Our results demonstrate that birds fed FM+BSFLM had significantly higher final liveweight, average daily weight gain (ADG), and low feed conversion ratio. Birds fed FM+BSFLM showed highest …

Developing Sight-Reading Proficiency In Music Education: A Synthesis Of Instructional Strategies And Pedagogical Approaches, Charles Clements Ii

Theses

Sight-reading is a foundational skill in music education that enables students to perform unfamiliar musical material independently. Despite its importance, instruction is often inconsistent and driven by performance priorities rather than systematic skill development. This thesis synthesizes existing research on sight-reading pedagogy to identify effective instructional strategies and organize them into a cohesive framework for educators.

By connecting research to classroom application, this project provides a practical, research-informed model for sight-reading instruction. The findings suggest that effective instruction requires a structured and integrated approach that supports both cognitive processing and musical performance, ultimately promoting greater student independence and musical literacy.

Gender Relations Within 18th And 19th Century Art And How It Affects A 21st Century Learner, Sophie Lima

Theses

This study constructs a curriculum unit comprising five lessons in feminist art history for middle school learners in 5th-8th grade. Drawing on theories and concepts from feminist art history, visual culture, and inquiry in art education, this curriculum aims to address the scarcity of age-appropriate materials in feminist art history. There is a need for curricular materials that help learners critically analyze issues of gender, identity, and power conveyed through visual culture. The curriculum encourages middle-grade students to engage with three approaches to art analysis: formalism, iconography, and feminism. The organized unit focuses on inquiry, interpretation, comparison, production, and evaluation. …

Holistic And Systems Thinking Modelling For Strategic Agriculture Production Planning In Sub-Saharan Africa, Bonoukpoè Mawuko Sokame, Ghislain T. Tepa-Yotto, Henri E.Z. Tonnang, Sabra Lewis, Christopher Suh, Rachel Zozo, Jeannette K. Winsou, Alpha Kamara, Joel Cornelius Runyu, Elfatih Abdel-Rhaman, Laura Schmitt Olabisi, Tahirou Abdoulaye

All Peer-Reviewed Publications

CONTEXT: Agriculture in sub-Saharan Africa (SSA) underpins food security, livelihoods, and economic growth, yet it faces mounting pressures from climate change, food insecurity, socioeconomic instability, and environmental degradation. While National Adaptation Plans (NAPs) and bioeconomic models are increasingly used to guide policy, most existing tools remain fragmented and fail to capture the complex interdependencies across agricultural, economic, social, technological, and environmental domains. OBJECTIVE: This study develops and applies a holistic bioeconomic systems model for strategic agricultural planning in SSA, aimed at identifying leverage points that enhance resilience, sustainability, and productivity. It specifically examines how climate-resilient crop variety (CRV) adoption and …

Climate Change Reduces Pollination Services And Sunflower Yields Across Europe And Northern Africa, Stella Gachoki, Clémence Riva, Danilo Bevk, Yamina Haider, Noureddine Adjlane, Ioannis Manthos, Bojan Stipešević, Zlatko Puškadija, Marin Kovačić, Leonidas Charistos, Fani Hatjina, Fabrice Requier

All Peer-Reviewed Publications

Sunflower (Helianthus annuus) productivity is highly dependent on pollinators, yet the effects of climate on pollination services and crop yield remain poorly understood. In this study, we investigate how temperature gradients influence flower-visiting communities, pollination services, and sunflower productivity across Europe and Northern Africa. We conducted standardized two-year (2022 and 2023) pollination exclusion experiments across 36 sunflower fields spanning a broad climatic gradient, from temperate regions in Slovenia to arid conditions in Algeria. We found that sunflower production (seed set, seed number, and oil content) relied heavily on insect pollination. However, this benefit declined with rising temperatures, likely due to …

Gc-Ms-Based Comparative Analysis Of Compounds In Host Plants And Insect Gut Extracts, Rita Dill, Kimberly Smith, Shelia Okoth, Xavier Cheseto, Anne Osano

All Peer-Reviewed Publications

Background/Objectives: Herbivorous insects feed on plant tissues to obtain nutrients necessary for growth and development while simultaneously ingesting diverse plant secondary metabolites. Understanding the fate of these compounds during digestion is important for advancing knowledge of insect nutritional physiology and diet-associated biochemical processes. This study aimed to comparatively profile metabolites in host plants and corresponding insect gut extracts to generate insights into compound transfer and compositional changes within these systems. Methods: Gas Chromatography-Mass Spectrometry (GC-MS) metabolomics was combined with Ultraviolet-Visible (UV–Vis) quantification of total phenols and flavonoids to compare host plant tissues and insect gut extracts in three systems: fall …

Climate-Driven Stochastic Modelling Of Crimean-Congo Haemorrhagic Fever Transmission In Uganda, P. G. Kpatchana, J. Aduda, K. M. Agboka

All Peer-Reviewed Publications

Crimean-Congo haemorrhagic fever (CCHF) is a climate-sensitive tick-borne zoonosis that remains a significant public health concern in Uganda, where temperature and vapour pressure deficit influence tick ecology and consequently disease transmission. This study aimed to develop and analyse a climate-driven stochastic model for CCHF transmission among ticks, livestock, and humans under environmental variability in Uganda. A compartmental transmission model was formulated and extended into a stochastic differential equation framework by incorporating multiplicative environmental noise. Climate-dependent tick recruitment, development, and mortality were parameterized using district-level temperature and vapour pressure deficit data to capture spatial heterogeneity in transmission risk. Theoretical analyses based …

Approach–Avoidance Motivation And Goal Adaptation In Chronic Pain: Predicting Pain Intensity And Interference, Paria Eshraghi, Deirdre Drake, Joanne Iddon, Joanne M. Dickson

Research outputs 2022 to 2026

Chronic pain is a major public health concern associated with disability, reduced functioning and psychological distress. Compared with biological studies, relatively little research has studied chronic pain from a psychological perspective, specifically motivation. Yet, motivation is considered fundamental to human functioning and drives human behaviour. The present study aimed to investigate whether distinct motivational and adaptive goal processes are implicated in chronic pain. The sample comprised 190 adult community participants who reported chronic pain for 3 months or more. Participants completed self-report measures of approach and avoidance motivation, adaptive goal processes, pain intensity, and interference. As hypothesised, avoidance motivation (but …

Engineering Immunity? Biotechnical Governance And The Experimental Failures Of Project Wolbachia In Singapore, Siew Ying Shee, Orlando Woods, Sayd Randle

Research Collection School of Social Sciences

This paper introduces the idea of ‘experimental failure’ to critically interrogate the limits of engineering biological systems for urban governance. Whilst experimentation through projects related to smart cities and eco-cities has garnered significant attention, biotechnical experiments––which manipulate living organisms through technology––remain underexplored. Unlike interventions leveraging non-living, inanimate systems, engineering life must contend with ecological ‘unruliness’ and social uncertainties. These complexities often resist straightforward quantification and exceed conventional evaluation frameworks, demanding a rethinking of what constitutes ‘success’ and ‘failure’ in such interventions. Drawing on ethnographic research with public health officers, pest management professionals and residents in Singapore, we analyse the government-led …

Dementia, Advance Directives, And Second-Order Volitions, Rand Hirmiz

Research Collection School of Social Sciences

This paper contributes to the ongoing debate over the authority of advance directives in cases where patients with dementia express desires that conflict with their earlier wishes. Drawing on Harry Frankfurt’s concept of second-order volitions, I argue that the preferences of the pre-dementia self (the “then-self”) should, in most cases, take precedence over those of the post-dementia self (the “now-self”) –  particularly in instances where the now-self has lost the capacity to form second-order volitions and is no longer able to meaningfully repudiate prior values and commitments.

Durable Benefits Of Learning-By-Teaching For Research Question Generation Performance: A Field Experiment, Stephen Wee Hun Lim, Sarah Shi Hui Wong, Piyawan Visessuvanapoom

Research Collection School of Social Sciences

Generating good questions is central to scientific inquiry. How can we improve this skill in classrooms? This field experiment showed that teaching others enhances students’ ability to generate higher-order research questions that create new knowledge. Whereas learning-by-teaching often involves delivering face-to-face or video-recorded lectures, we tested its efficient implementation via writing a verbatim (i.e., word-for-word) teaching script, exactly as how one would orate a lecture. In a research and statistical methods course, 199 undergraduates studied statistical concepts by writing verbatim teaching scripts or study notes. One month later, students’ long-term learning was assessed on a high-stakes test, whereby they explained …

Webinar 1 Content-Based Eld, Slide Deck 6.10.26, Center On English Language Proficiency

Webinars

No abstract provided.

Effects Of Overcorrection On Mitigating Uncontrolled Tipping During Incisor Retraction Using Clear Aligners: Finite Element Analysis And In Vitro Experiment, Jianing Wang, Niko Burger, Bo Wang, Linxia Gu, Pengfei Dong

Biomedical Engineering Faculty Research and Publications

Uncontrolled tipping during incisor retraction with clear aligners continues to limit orthodontic treatment. Different countermeasures have been proposed to improve the predictability of aligners, such as power ridges and attachments, while their efficacy requires further investigation. This work investigated the biomechanics of the overcorrection in reducing the tipping angle and moment during incisor retraction with a clear aligner, through in vitro experiments and finite element analysis (FEA). Specifically, the influence of overcorrection angle (1 deg), retraction distance (0.15 mm), and the combination of both were assessed through in vitro experiments and the finite element simulation. Further computational simulations were conducted …

African American Business Owners' Descriptions Of Experiences With Lending Practices, Wannika R. Muhammad

Electronic Theses and Dissertations

Entrepreneurship has remained an influential and unfulfilled goal for African Americans from the 1800s until now. Due to barriers in lending practices, increased business retention rates for African American business owners still need to be achieved. The lack of credit and lending resources hinders business growth and retention. Although Black-owned firms contribute significantly to the U.S. economy, they remain classified as underutilized entities that benefit the least, without adequate access to financial services, such as banking and lending opportunities. This study’s participants consisted of 12–15 African American business owners in central Texas, through a qualitative descriptive exploration of their experiences …

Isolation And Self-Efficacy Among Texas Educators With Disabilities Post-Covid: A Narrative Inquiry, Paul M. Nimon

Electronic Theses and Dissertations

The purpose of this qualitative inquiry was to explore the narratives of 10 current Texas public school educators with disabilities, as defined by the Americans with Disabilities Act, to understand how these narratives shaped their perceptions of burnout in relation to isolation and self-efficacy in the aftermath of the COVID-19 pandemic. The specific problem addressed the systemic, cultural, and interpersonal barriers that contribute to emotional exhaustion and professional marginalization for this population. The paradigm used was action research. The specific research methodology was a qualitative narrative inquiry. Data collection methods included 60-to-90-minute semistructured interviews conducted via Zoom and transcribed for …

20260601: Dr. John Deaver Drinko Academy Records, 1892-2020, John Deaver Drinko Academy

Guides to University Archives

These items include materials from the office of the John Deaver Drinko Academy at Marshall University from 1892-2020. Items were received in 2026 from Dr. Montserrat Miller, the Executive Director of the Drinko Academy from 2018-2026. Included in this collection are historic documents from her time as faculty but primarily from her time in the Drinko Academy and the departments earlier records. There are lots of photographs, honors college receptions, assorted media like VHS and DVDs regarding various events, among a host of other content from former Drinko Academy EDs. Please download the finding aid for a full list of …

Examining How Student Involvement And Identity Shapes Perceptions Of Cal Poly Administrative Communication And Organizational Change, Ellenor Rose Nunes

Communication Studies

This study examined the relationship between student organization involvement, sense of belonging, and perceptions of administration at California Polytechnic State University (Cal Poly). Using survey data collected from 176 students, independent samples t-tests and correlation analyses were conducted in SPSS Version 25 to examine whether involvement in student organizations was associated with perceptions of administration and institutional belonging. Results indicated no significant relationship between levels of involvement and perceptions of administration or organizational change communication. However, students involved in student organizations reported significantly greater feelings of mattering and belonging compared to non-involved students. Additionally, students with stronger feelings of belonging …

Autonomous Vision-Based Litter Collection Rover, Dante Michael Benedetti, Benjamin Scott Tavares, Nathan Heil

Electrical Engineering

This report documents the design, implementation, and testing of an autonomous litter-collection rover developed as a Senior Project Design Lab (EE 460/463/464) at California Polytechnic State University. The rover integrates autonomy, computer vision, embedded real-time control, mecanum-wheel omnidirectional mobility, and a two-degree-of-freedom robotic arm to detect, approach, and collect small ground-level litter such as bottles, wrappers, and paper fragments.

The system uses a two-layer compute architecture: an NVIDIA Jetson Orin Nano running ROS 2 for perception, SLAM, and path planning, paired with an STM32L4A6ZG microcontroller for real-time motor control and odometry. The robot is built on a multi-level aluminum frame …

Test Bench Pcb Design For A Vlsi Grid Cell Chip, Nicholas Bruk, Jason Alexandar

Electrical Engineering

This report presents the design, implementation, and validation of a custom printed circuit board (PCB) test bench for a VLSI grid cell emulation chip. The final board provides two independently adjustable 5V supplies using LM317 linear regulators, eleven potentiometer-controlled bias voltages, high-impedance buffering of analog outputs via an MCP6022 dual operational amplifier, and buffering of digital outputs using a 74HC244 buffer IC. The design includes a 40-pin DIP socket for the VLSI chip, extensive test-point headers for probing, and a 9V battery input for portable operation. Five fully functional boards were fabricated using ExpressPCB and assembled with through-hole components. An …

Estimation And Control For Physical-Ai Aerial Robots, Joshua S. Crain

Electrical Engineering

This project investigates the modeling, control, and state estimation of a Crazyflie 2.0 quadrotor using both a custom nonlinear simulation and the NVIDIA Isaac Lab robotics simulation framework. A twelve-state rigid-body dynamic model was developed to represent the translational and rotational motion of the vehicle, and classical cascaded PID control was implemented for position and attitude stabilization. To improve state awareness in the presence of sensor noise, Kalman Filter (KF) and Extended Kalman Filter (EKF) algorithms were integrated for state estimation. Initial controller development and verification were performed using a custom MATLAB/Python simulation environment based on numerical integration of the …

Portable Food Pasteurization Using Pulsed Electric Fields (Pef), Thomas E. Mcmillan Iii

Electrical Engineering

Foodborne illnesses remain a significant public health concern, motivating continued development of alternative food pasteurization technologies. Pulsed electric field (PEF) treatment is a non-thermal pasteurization method that inactivates microorganisms through electroporation while minimizing thermal degradation of food products. The long-term objective of this project was development of a portable PEF food pasteurization system.

An iterative design approach was used to investigate generation of the high-voltage pulses required for PEF treatment. Multiple pulse forming network topologies were evaluated through simulation, leading to selection of a solid-state Marx generator architecture. A low-voltage five-stage prototype was designed, constructed, and tested to validate the …

Designing Trustworthy Ai For Skincare Recommendations, Sofia Moretti

Graphic Communication

This project explores how UX design can improve transparency and trust in AIpowered systems through the design of a skincare recommendation experience. I designed and tested a high-fidelity prototype that incorporated explanation layers and user-controlled adjustments to help users better understand how recommendations were generated and how their inputs influenced the results. Through usability testing, I found that clear recommendation reasoning and visible user control improved user trust, understanding, and confidence when interacting with AI-powered systems.

Let's Talk Twenties, Yuwa R. Tennen

Graphic Communication

“Let’s Talk Twenties” is a senior design project that explores what it really feels like to be in your twenties...the highs, the lows, and everything in between. It focuses on creating an open, relatable space where conversations about identity, relationships, and personal growth feel honest and normalized. The goal is to break away from the pressure of having everything figured out and instead highlight the shared experiences that define this stage of life.

Through thoughtful short-form content, branding, and storytelling, the project combines engaging visuals with real, meaningful content to connect with young adults. It emphasizes authenticity, inclusivity, and emotional …