Digital Commons Network^™

Combining Green Analytical Methods And Machine Learning To Develop Urinary Fatty Acid Models For Cancer Detection, Elizabeth Noriega Landa

Open Access Theses & Dissertations

This study aimed to explore fatty acids (FAs) as non-invasive biomarkers for prostate cancer (PCa) detection and prognosis, and their potential applications in other cancers. The objectives of this study were: 1) Develop a non-invasive urinary FAs-based model for diagnosing PCa; 2) Develop a FAs-based liquid biopsy model for non-invasive monitoring of PCa progression; 3) Investigate FAs composition in periprostatic adipose tissue (PPAT) collected from PCa positive patients; 4) Investigate the potential of urinary FAs biomarkers for diagnosing clear cell renal cell carcinoma (ccRCC) and ovarian cancer (OC).For the PCa diagnostic model, urine samples from 334 biopsy-confirmed PCa-positive and 232 …

Analysis Of Drying Behavior Of Robocasted Barium Titanate, Abigail Ortega

Open Access Theses & Dissertations

Finding an adequate ceramic formulation for material extrusion is a time-consuming process. The necessary equipment may be unavailable to perform the desired test. This study demonstrated an alternative to observe a material after extrusion to understand its drying process. This study focused on 55 solid loading volume percent and a 39 solid loading volume percent, each with two different binder treatments focusing on fresh same day made binder, a 30 day old, aged binder and lastly an artificial binder obtained by a fuming process. Firstly, a formulation was created and loaded onto a pressure-based syringe to be extruded with a …

Building Positive Gender Expressions Among Mexican-American College Students, Nezahualcóyotl Paniagua-Jiménez

Open Access Theses & Dissertations

This thesis explores the need for college programs to nurture and support positive gender expressions among Mexican-American college students. It does so through a historical and cultural analysis of gender identities and expressions within the Mexican community and how they impact the lives of Mexican-American college students. Additionally, it offers an exploration of potential practices and programs that support the development of positive identity and gender expressions, with a lens of intersectionality, to ensure students are allowed to critically explore and develop gender identities that move away from domination/subservience power structures and that are founded on their unique cultural background.

Establishing The Validity Of A Measure Of Implicit Bias Toward People With Alcohol Use Disorder, Erin Marie Portillo

Open Access Theses & Dissertations

Alcohol use disorder has been identified as one of the major burdens of disease but also remains one of the disorders with the lowest treatment prevalence. For individuals who seek treatment for their alcohol use disorder, they may experience barriers that impact their treatment for alcohol use disorder. These barriers may extend to a person’s beliefs, attitudes, and stigma. While attitudes and beliefs refer to their perceived need for treatment and beliefs of self-reliance, stigma is multistep process that makes way for stereotypes, prejudice, and acts of discrimination to take place. With labels such as “alcoholic” implying negative connotation and …

Examining The Effects Of A Week-Long Social Media Abstinence Intervention, Iweek, On General Well-Being, Mental Health, And Body Image Concerns In Latina College Students, Roberto Sagaribay

Open Access Theses & Dissertations

Latina college students, on average, spend approximately 30 hours per week on social media, highlighting the pervasive influence of social media on their lives. While social media can facilitate interpersonal relationships, its impact on mental and physical health is evident in the literature. Problematic social media use has been associated with increased rates of depression, anxiety, and decreased life satisfaction. Additionally, exposure to idealized images on social media platforms often leads to lower body satisfaction, particularly among women. Social media may also influence eating behaviors through the abundance of food advertisements and contribute to sedentary behavior, as individuals spend significant …

Produced Water: Characterization And Treatment, Ramon Antonio Sanchez Rosario

Open Access Theses & Dissertations

In recent years, environmental concerns have urged companies in the energy sector to modify their industrial activities to facilitate greater environmental stewardship. For example, the practice of unconventional oil and gas extraction has drawn the ire of regulators and various environmental groups due to its reliance on millions of barrels of fresh water for hydraulic fracturing well stimulation, which is generally withdrawn from natural sources and public water supplies. Additionally, this process generates two substantial waste streams, which are collectively characterized as flowback and produced water. Whereas flowback water is comprised of various chemical additives that are used during hydraulic …

Synthesis Of Neoglycoproteins As Potential Biomarkers For Chagas Disease And Cutaneous Leishmaniasis Caused By Leishmania (Viannia) Braziliensis, Eileni Rodriguez Gil

Open Access Theses & Dissertations

Protozoan parasites are responsible for causing numerous diseases in humans and mammals worldwide. Among them are Chagas disease (CD), caused by the parasite Trypanosoma cruzi (T. cruzi), and tegumentary leishmaniasis (TL), caused by the parasite Leishmania (Viannia). Both diseases coexist in many regions of Latin America, and current hurdles to differentially diagnose them and determine chemotherapy success need to be overcome. CD can be diagnosed by traditional serological tests and polymerase chain reaction (PCR), but disadvantages of these methods are that they may produce false negatives because the antigens used in commercial CD kits are not conserved across all T.cruzi …

Characterizing The Mentoring Landscape In An Online Biology Cure: An Examination Of Student And Graduate Teaching Assistant Perspectives And Outcomes, Karen Alejandra Santillan

Open Access Theses & Dissertations

Both undergraduate research experiences (UREs) and course-based undergraduate research experiences (CUREs) provide students with benefits and opportunities such as improving technical skills and making connections that provide resources. Where these two experiences differ is accessibility. Similar to their URE counterpart, CUREs entail mentorship on the part of the faculty/graduate teaching assistant (GTA) instructor (Dolan, 2016). There is general agreement that mentoring has many benefits for undergraduate STEM students, such as an improvement in retention rates, increased confidence and self-efficacy, and a more established sense of belonging and science identity (Dolan, 2016). CURE instructors often adopt the role of “mentor” in …

Computational Investigation Of Transition Metal Photoredox Catalysis: Redox Property Tuning Via Ligand Modification, Christian Fernando Sandoval Pauker

Open Access Theses & Dissertations

In the last decade, photoredox catalysis has become a powerful tool in synthetic chemistry. It relies on the ability of catalytic systems that facilitate energy-demanding redox reactions thanks to photoinduced electron transfer processes. This dissertation focuses on the computational investigation of the redox properties of transition metal photoredox catalysts using density functional theory (DFT) calculations. The research systematically explores the effects of altering redox-active ligands on the thermodynamics of electron transfer events in the photoredox cycle. The electronic structure changes throughout oxidative and reductive quenching cycles are analyzed, with a particular focus on Cu(I) complexes. Through computational techniques, insights into …

Atlas-Based Analysis Of The Neural Projections From The Lateral Hypothalamic Area To The Lower Brainstem In The Adult Male Rat, Jessica Valeria Salcido Padilla

Open Access Theses & Dissertations

Within the last decade, the number of diseases associated with dysregulation of the neural circuits responsible for energy balance, glucosensing, and feeding control has increased. One brain region containing these circuits is the lateral hypothalamic area (LHA), which plays an important role in the sleep/wake cycle, energy balance, and motivated behavior. Although the LHA has been termed a â??feeding centerâ??, other regions within the hindbrain are known for the regulation of similar functions including energy balance, glucosensing, and feeding control. While many studies have explored and reported projections from the LHA to the hindbrain, few have further investigated the interconnections …

"Inwombed" Expressions Of Anxiety: Myhth, Humor, And The Absurd, Jonathan Taylor

Open Access Theses & Dissertations

Abstract poetry collection.

The Daughters Of La Malinche: A Heideggerian Analysis Of The Pazian Archetypal Masks Portrayed In Art, At-Ziry Aileen Torres

Open Access Theses & Dissertations

In this thesis, I present a Heideggerian phenomenological analysis of the Pazian archetypal masks present in The Labyrinth of Solitude, such as El Macho, La Llorona, La Mala Mujer, La Chingada, and La Malinche, and how these masks are represented and depicted by women in art. I analyze the authentic or inauthentic identity and conditions expressed by Mexican women in art through a mimetic lens and extend that analysis to gendered concerns that have emerged in the past fifty or so years in Mexico and the U.S. Mexico border. Such issues include the pervasive machismo culture and the alarming increase …

Abortion Funds As Care Work: Navigating The Emotional Tolls Of The Texas Executive Order Abortion Ban And Covid-19 Pandemic, Brianna Trejo

Open Access Theses & Dissertations

This qualitative study explores the experiences of abortion fund staff and volunteers amidst the unprecedented challenges posed during the early months of COVID-19 and the Texas Executive Order. Through analysis of semi-structured interviews, we aimed to identify the shared experiences of staff and volunteers during this time. Four categories of experiences were identified: (1) Reproductive Justice, (2) Emotional Support, (3) Creating a Community of Care, and (4) Emotional Burnout. Our findings revealed that to navigate the uncertainties of the pandemic and Executive Order, staff and volunteers adapted a community of care model deeply rooted within the framework of reproductive justice. …

Physics-Guided Scan Paths Optimization For Controlled Microstructure In Laser Powder Bed Fusion, Augustine Twumasi

Open Access Theses & Dissertations

Laser Powder Bed Fusion (L-PBF) is a renowned additive manufacturing technique, celebrated for its capability to construct intricate metal components with remarkable precision. However, one of the main challenges with L-PBF is the formation of complex microstructures, which can significantly impact the final material properties. To address this issue, our study proposes a physics-guided and machine-learning-aided approach to optimize scan paths for achieving desired microstructure outcomes, such as the generation of equiaxed grains that enhance material properties. By using phase-field modeling, a physics-based computational method, we gain insights into microstructure evolution. To reduce computational costs, we train a surrogate machine-learning …

Automated Composition Of Multivariable Scientific Workflows Considering Scientific Assumptions, Raul Alejandro Vargas Acosta

Open Access Theses & Dissertations

Many ground-breaking scientific experiments require the execution of multiple complex scientific computations. Thus, scientific workflows (i.e., a sequence of scientific computations) have received significant attention, more specifically, the automated composition of scientific workflows. Scientific workflows that repurpose data may have unique scientific assumptions that need to be considered when composing a workflow. Workflow composition tools have enabled a wider range of stakeholders (e.g., policymakers, the general public, and researchers) to create and execute workflows; however, domain expertise is still required for these tasks. The overarching goal of this work is to further improve the automatic composition of scientific workflows by …

Staggered Boards And Human Capital Disclosure, Xue Yang

Open Access Theses & Dissertations

This article examines the effects of staggered boards on human capital management (HCM) disclosure quality. I find that firms with staggered boards exhibit significantly better HCM disclosure scores than non-staggered boards. Additionally, firms that transition from staggered boards to non-staggered boards are shown to experience significant decreases in their HCM disclosure scores. These results are robust to the exclusion of firms that switch to or from staggered boards to non-staggered boards, propensity score matching, and alternative disclosure quality measures. While various cross-sections and the usefulness of HCM disclosure information for analyst forecasts are explored, the results were not significant.

Agricultural Groundcover Update March 2024, Justin Laycock

Natural resources published reports

• In March, over 10% (1,577,000 ha) of the arable farmland in the south-west of Western Australia had less than 50% vegetative groundcover, which is inadequate to prevent wind erosion.

• The northern grainbelt had the highest risk of wind erosion and over 20% of this farmland had inadequate groundcover.

• About 1.3% (191,000 ha) of arable land had a high to very high risk of wind erosion because groundcover was less than 30%.

Will Consumer-Generated Reviews And Electronic Word-Of-Mouth Communications Affect Subjective Norm Perceptions, Attitudes Toward Social Commerce, And Social Shopping Intensions Among Gen Z Consumers?, Adebusola Azeezat Adewale

Open Access Theses & Dissertations

Social commerce has become a global phenomenon in recent years. Its convenience and accessibility have revolutionized how consumers shop and interact with brands and merchants. Gen Z consumers make up the majority (55.5%) of social buyers, and they are likely to be influenced by consumer-generated reviews (CGRs) and electronic word-of-mouth (eWOM) on social media. This thesis draws on the Theory of Planned Behavior (TPB) and employs a quantitative online questionnaire to determine whether CGRs and eWOM influence subjective norms (SN) perceptions, attitudes toward social commerce (ASC), and social shopping intention (SSI) of Gen Z consumers. The theoretical framework also included …

Untold Stories: Exploring Queer And Genderqueer Students’ Perceptions Of Sense Of Belonging And Experiences At One Historically Black University, Tammy D. Lane

All Dissertations

This study used a basic interpretative qualitative design, using a case study as the theoretical approach to examine the experiences of Black queer students, particularly as they foreground a sense of belonging on a historically Black college and university (HBCU) campus. Extant literature demonstrated that queer cohorts are likely to experience isolation and a sense of not belonging at HBCUs due to tradition (Davis, et al., 2020; Lenning, 2017; Mobley & Johnson, 2019). Queer students’ sense of belonging can influence behaviors such as persistence, engagement, academic achievement, and a sense of self (Garvey, 2020; Squire et al., 2018; Strayhorn, 2019). …

Offshore Wind In New York City: Is Brooklyn Tilting At Windmills?, Nathan Kensinger, Alex Diaz-Casos

Publications and Research

This paper explores how the strategic expansion of offshore wind energy in the United States will reshape the waterfront of New York City, with a specific focus on the borough of Brooklyn. The U.S. Federal government has committed to developing a robust offshore wind industry along the East Coast, and several State governments in this region have made their own commitments to receive significant amounts of energy from offshore wind facilities. This emerging industry will potentially invest billions of dollars into new infrastructure and could lead to the creation of thousands of new jobs. However, the offshore wind industry in …

Fighting For A Health Diagnosis: An Autoethnographic Journey Into The Role Of Access And Limitations Of Resilience In The Face Of Poverty, Josette Pelatan

Open Access Theses & Dissertations

This research represents a highly personalized account of the complexities, interpretations, and reflections of the journey of a doctoral student navigating the challenges of health through access on a U.S.-Mexico border. Using myself as the subject and the researcher in the social context of schooling provided the impetus for this self-study. Through an insider’s vantage point, I have chronicled and traced the experiences of my own identities’ transitions and multilayered intersectionality using the qualitative methodology of autoethnography. This genre of qualitative research brings the reader closer to the subculture studied through the author’s experiences.

While every story has its unique …

A Word From The Writing Team (May 2024), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Join Us for Our Virtual Writing Retreat on May 3rd
• Save the Date for the 16th Annual Jefferson Faculty Days: June 5th & 6th
• Scott Memorial Library Archive Renovations Are Done—Come See!
• Thomas Jefferson University Has Updated Its Mission Statement
• Publication Spotlight
• Jefferson's AI Library Guide is Available on the Library Website
• The OPWPC Canvas Page Offers Helpful Tools

Local Existence Of Solutions To A Nonlinear Autonomous Pde Model For Population Dynamics With Nonlocal Transport And Competition, Michael R. Lindstrom

School of Mathematical & Statistical Sciences Faculty Publications

Highlights

• Partial differential equation models are ubiquitous in applied sciences.

• A partial differential equation based in ecology is studied for solution existence.

• Energy methods and convergence analysis lead to local classical solutions.

Abstract

In this paper, we prove that a particular nondegenerate, nonlinear, autonomous parabolic partial differential equation with nonlocal mass transfer admits the local existence of classical solutions. The equation was developed to qualitatively describe temporal changes in population densities over space through accounting for location desirability and fast, long-range travel. Beginning with sufficiently regular initial conditions, through smoothing the PDE and employing energy arguments, we obtain a sequence …

Response To Mateo Duque, “The Multiple Audiences Problem In Plato’S Apologia”, Sophia A. Stone

Faculty and Staff Publications & Presentations

No abstract provided.

Commencement Program, May 2024, Bemidji State University

Commencement Programs

No abstract provided.

Persistence And Evolution Of Pseudomonas Aeruginosa Following Initiation Of Highly Effective Modulator Therapy In Cystic Fibrosis, Catherine R. Armbruster, Yasmin K. Hilliam, Anna C. Zemke, Samar Atteih, Christopher Marshall, John Moore, Junu Koirala, Leah Krainz, Jordan R. Gaston, Stella E. Lee, Vaughn S. Cooper, Jennifer M. Bomberger

Biological Sciences Faculty Research and Publications

Today, more than 90% of people with cystic fibrosis (pwCF) are eligible for the highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy called elexacaftor/tezacaftor/ivacaftor (ETI) and its use is widespread. Given the drastic respiratory symptom improvement experienced by many post-ETI, clinical studies are already underway to reduce the number of respiratory therapies, including antibiotic regimens, that pwCF historically relied on to combat lung disease progression. Early studies suggest that bacterial burden in the lungs is reduced post-ETI, yet it is unknown how chronic Pseudomonas aeruginosa populations are impacted by ETI. We found that pwCF remain infected throughout their …

The Role Of Maternal Emotion Regulation In The Relationship Between Maternal Adverse Childhood Experiences (Aces), Negative Parenting, And Child Externalizing Behaviors, Maddison Knott

Master's Theses

Exploration of the effects of maternal Adverse Childhood Experiences (ACEs) on child externalizing behaviors were conducted in the proposed study. Subtypes of ACEs, such as household dysfunction and maltreatment, and their effects on child externalizing behaviors were also examined. Maternal ACEs have shown to have negative effects on their children through use of more negative parenting practices (NPP). However, the role of maternal difficulty in emotion regulation in the link between maternal ACEs, NPP, and child externalizing behaviors has not been previously shown in the literature. Thus, the present study aimed to examine these relations, specifically with NPP as a …

3d Analysis Of Fe-Ti Oxides And How They Affect Crystal-Plastic Deformation In Atlantis Bank, Southwest Indian Ridge, Sarah Hill

Master's Theses

This project focuses on the importance of the relationship between Fe-Ti oxide abundance and interconnectivity, and crystal-plastic deformation in Atlantis Bank, Southwest Indian Ridge by utilizing Micro-CT scanning. This was done through comparing the Micro-CT scans of 15 samples from three different Ocean Drilling Program and International Ocean Discovery Program drill holes using the Nikon NIS Advanced Research 3-D visualization program and producing plots and statistics from MATLAB. Results indicate a wide range of textures across a range of crystal-plastic fabric intensity and Fe-Ti oxide abundance. Ultimately, there was a generally positive relationship between depth, CPF intensity, and Fe-Ti oxide …

Outside Influence And Troop Deployment, Cara Wilson

Master's Theses

This paper examines the role that the President, the public, and the media played in troop deployment during the Afghanistan War. I hypothesized that each variable would influence troop deployment. Using a linear regression, I found that there is a positive relationship between the media and troop deployment. I concluded that media coverage did not influence troop deployment, but highlighted what was happening in Afghanistan. With the public, there is a negative relationship between the public and troop deployment. While troops increased, the public decreased in their support for the war. I conclude that the public did not have a …

Assessing The Independent Role Of Moral Foundations In Attitudes Toward Various Justifications For Abortion, Saba Shahid

Master's Theses

Although many states have legal frameworks that restrict abortion to certain situations, largely associated with health risks to the mother, child or both, other factors, such as financial stability, emotional readiness, and partner's presence, are not covered by existing laws, though they may be critical factors contributing to abortion decisions. To assess the role of these factors, participants (N= 302) were recruited online via Prolific Academic and randomly assigned on a between participants basis to view a single vignette that manipulated abortion justification category (financial, emotional, partner) and the presence/absence of justification. They reported the extent to which …