Digital Commons Network^™

Reactive Oxygen Species Production In Head Regeneration Of Planaria From Cadmium Exposure, Natalie Gonzalez

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Exposure to cadmium, a pervasive neurotoxic chemical found in our environment, poses significant health risks, disrupting various physiological systems and fostering carcinogenesis. Commonly found in everyday items like cigarettes, batteries, and plastics, cadmium disrupts the equilibrium between reactive oxygen species (ROS) production and cellular repair mechanisms, culminating in oxidative stress and potential cell damage. In toxicological and pharmaceutical research, planarians offer valuable insight for understanding how exposure to chemicals akin to human scenarios can alter biological systems. This experiment addresses the effect cadmium chloride (CdCl₂) has on planarian regeneration and whether antioxidants can mitigate those adverse outcomes. Our …

The Optimal Timing Of Abscisic Acid Treatment In Arabidopsis Under Drought And Salt Stress, Khelia Gihozo

Graduate Student Dissertations, Theses, Capstones, and Portfolios

As climate change intensifies, harsh environmental conditions, such as increased drought and salt levels, will pose significant challenges to agricultural productivity globally. It is important to develop strategies for plants to tolerate these adverse conditions. This study aims to investigate how well the timing of abscisic acid (ABA) treatment can promote resistance to salt and drought in Arabidopsis thaliana grown on Murashige and Skoog agar medium. The study evaluates both wild-type and transgenic lines overexpressing the DREB2A gene, a transcriptional activator involved in the stress response of plants. Plants were exposed to drought and salt stress as they matured. Followed …

Investigating Potential Improvements To Mbse Software To Support Dodaf, Jennifer Marie Kimpson

Theses and Dissertations

The integration of models created through model-based systems engineering methods with DoDAF is not a new concept. By creating DoDAF-aligned models, DoD program managers are following DoD guidelines to hopefully achieve more effective communication with stakeholders and improve efficiency of their programs. With the use of MBSE tools to create these models, DoD program managers are able to take further advantage of the benefits of MBSE methods. However, even with the use of MBSE tools, there continue to be issues throughout DoD programs. The literature has shown that a continuous improvement approach regarding the use of MBSE tools with DoDAF …

Space Transformation For Open Set Recognition, Atefeh Mahdavi

Theses and Dissertations

Open Set Recognition (OSR) is about dealing with unknown situations that were not learned by the models during training. In OSR, only a limited number of known classes are available at the time of training the model and the possibility of unknown classes never seen at training time emerges in the test environment. In such a setting, the unknown classes and their risk should be considered in the algorithm. Such systems require not only to identify and discriminate instances that belong to the source domain (i.e., the seen known classes contained in the training dataset) but also to reject unknown …

Caelus: Cubesat Array For The Exploration Of The Uranus System, Dylan George Heidenrich Barnes

Theses and Dissertations

Following recommendations from the 2023-2032 Planetary Science and Astrobiology Decadal Survey, we propose a novel Pre-Phase A level Uranus exploration mission concept that is centered on using swarms of small spacecraft to observe the Uranus system. This mission could act as a supplement to the Flagship Uranus Orbiter and Probe mission detailed in said Decadal Survey. We propose launching a 4,500 kg spacecraft on an Earth-Jupiter-Uranus gravity assist transfer trajectory with a transfer time of six years, launching in 2033 and arriving at Uranus in 2039. This shorter transfer time and accelerated development timeline would allow for an earlier arrival …

Cross-Framework Validation Of Cnn Architectures: From Pytorch To Onnx, Shreya Nandanwar

Theses and Dissertations

This research presents CIPAC (CNN Inter-framework Parameter Analysis and Comparison), a validation approach designed to ensure the integrity of Deep Learning models during their transfer between computational frameworks. Although initially tested on Convolutional Neural Networks (CNNs), CIPAC is versatile enough for various Deep Learning architectures. It goes beyond traditional methods that focus on output accuracy, by examining the models’ architecture, parameters, and components to maintain consistency after transitions, like moving from PyTorch to ONNX framework. Inspired by software architecture’s stringent validation standards, CIPAC addresses the challenges of working with Machine Learning models on different platforms, making it an essential tool …

Investigating Factors Influencing Blockchain Adoption In Saudi Healthcare Data Management, Noura Mohammad Alkhalifah

Theses and Dissertations

Blockchain technology can potentially address security and privacy issues concerning the collection, storage, and sharing of healthcare data. However, its adoption within the healthcare sector is nascent in Saudi Arabia. This underutilization prompted our investigation into the determinants influencing blockchain adoption, intending to fully empower the Saudi healthcare sector to leverage blockchain capabilities. To achieve this, an extensive literature review was conducted to identify the pivotal factors encompassing technology, organization, and environment (TOE) that affect the successful implementation of blockchain technologies in managing healthcare data within the Saudi context. Utilizing the TOE framework, this study formulated three hypotheses concerning the …

Embracing Ai With Integrity: Recommendations For Authors And Reviewers At American Business Review, Subroto Roy, Kamal Upadhyaya

American Business Review

As Editors of the American Business Review (ABR), we are navigating a complex landscape as the rapid integration of Artificial Intelligence (AI) into academic research unfolds. This digital transformation era offers remarkable opportunities yet poses significant challenges, particularly in educational contexts. As teachers, we've all observed a surge in AI usage among students where outputs often appear coherent initially but may lack depth or relevance to the class content. Many of these instances underscore critical aspects of AI, such as the "black box" problem, where the decision-making processes of AI systems are opaque, making it difficult for users to understand …

Establishing New Links Between Hrm Practices And Knowledge Workers’ Retention In Healthcare Sector: Knowledge Sharing Generating Moderating Effects, Riya Gupta, Rachna Agrawal, Arti Gupta

American Business Review

Knowledge sharing is the fundamental measure through which knowledge workers can significantly contribute to innovation and eventually the competitive advantage of the organization. Drawing upon the knowledge-based view of firms, the present study aims to examine the moderating role of knowledge sharing on the relationship between HRM practices and knowledge workers’ retention in the healthcare sector. After the COVID impact, healthcare knowledge workers have become a point for wide scholarly discussion and appropriate HRM practices should be implemented to amplify their probability of a longer stay in the organization. Hence, this research has incorporated PLS-SEM for empirical investigation which is …

To Sue Or Not To Sue?: Foreign-Sounding Ceo Name And Class-Action Lawsuits, Gajanan Ganji, Arati Kale, Devendra Kale

American Business Review

In this paper, we investigate if the perceived name-based ethnicity of CEOs has any relationship with the likelihood of shareholder class-action lawsuits. Using machine learning algorithms on CEO names, we develop an objective proxy of name-based ethnicity and find that firms managed by ‘foreign-sounding’ CEOs exhibit a lower likelihood of class-action lawsuits. Our results are robust to matched sample analysis, Heckman two-stage selection, alternate model specifications as well as use of an alternate proxy. We further find that succession of a foreign-sounding CEO by a non-foreign-sounding CEO increases the likelihood of class-action lawsuits. Our paper has important implications for firms, …

Designing Efficient And Equitable Freight Services Markets For Sustainable Economic Performance, Arim Park, Mark Rodgers, Soohyun Cho

American Business Review

Despite the indispensability of freight trucking services and truckers’ role as critical stakeholders in supply chains, relatively little attention has been paid to analyzing small independent truckers’ roles. Shippers often prefer working with larger trucking companies to the detriment of smaller independent truckers, who must grapple with an inherently disadvantageous job market. Furthermore, in the presence of uncertainty or peak demand periods, trucker shortages can pose significant economic challenges for shippers and downstream customers. In this paper, we propose an analytical framework to address these challenges in efforts to enhance the sustainability of the freight service industry. We formulate and …

Equity Returns Around Extreme Loss: A Stochastic Event Approach, Xiaomin Guo, Huijian Dong, Gary A. Patterson

American Business Review

We define an extreme loss event as a daily return at the left tail of negative two standard deviations of all daily returns for a specific stock. Prior studies focus on the relationship between extreme losses and specific anticipated announcements. Our study identifies the extreme loss events after they are randomly realized, and examines the return patterns of the equities in question on stochastic event setups. We investigate the daily returns of 2,651 stocks traded in the U.S. equity markets and identified 217,990 extreme loss events from the 1950s to early 2019. Our findings show that after an extreme loss, …

Firm Type And Unconditional Conservatism: The Indian Experience With Ifrs Convergence, Debarati Basu

American Business Review

This paper investigates how private and public firms vary with respect to unconditional conservatism in financial reporting in the pre and post IFRS worlds. I consider unconditional conservatism (UC) which pre-empts the more commonly studied conditional conservatism, private firms that are differently regulated, IFRS convergence instead of the more uniform IFRS adoption and an emerging market. Using a large Indian sample of 63,000 observations across more than 15,500 firms (~41% are private) over 10 years (2011-2020), I show that private firms are less unconditionally conservative than public firms. Also, contrary to literature, IFRS convergence increases conservatism in India and reduces …

Asset Returns And Economic Uncertainty: A Cross-Country Analysis, Javed Bin Kamal, Akhand Akhtar Hossain, Omar Al Farooque, Mark Wohar

American Business Review

This paper examines the effects of economic uncertainty (idiosyncratic vis-à-vis common uncertainty) on equity, bond and housing returns across both developed and developing countries. Building on International/Intertemporal Capital Asset Pricing Model (ICAPM), we find that economic uncertainty exerts negative effects on equity, bond and housing returns. When we decompose economic uncertainty into two parts: idiosyncratic and common economic uncertainty, we find that ‘idiosyncratic uncertainty’ affects equity, bond and housing returns more negative and pronounced than ‘common’ uncertainty, where investors do not demonstrate differences in responses to the different dimensions of uncertainty. Moreover, there are weak lagged effects of economic uncertainty …

From Hr Practices To Hr Performance: A Psychological Ownership Meta-Analysis Across Cultures, Franziska M. Renz

American Business Review

This study utilizes psychological ownership theory as theoretical framework to examine high-performance work practices, and attitudinal and behavioral performance as associations of psychological ownership on the population level. Psychological ownership describes a mindset which allows individuals to experience ownership feelings for a target (e.g., organization) regardless of legal ownership rights. Further, psychological ownership theory is integrated with and extended by contingency theory to analyze the moderation effects of societal culture. These effects have been assumed for over 30 years but hardly backed by empirical evidence from cross-cultural samples. Thus, this study analyzes data from 351,919 individuals who participated in 139 …

Urban Unemployment Duration Analysis In Post-Reform China, Soumyatanu Mukherjee, Soumya Roy

American Business Review

We link China’s accession to the WTO with the unemployment duration of urban jobseekers. Using data from the Rural Urban Migration in China (RUMiC) of a survey conducted in early 2008, we construct an inflow sample of those who started a period of joblessness between January 2002 and December 2007 to estimate the unemployment duration for local urban jobseekers. Deploying the Cox Proportional Hazards and Accelerated Failure Time models, we find reduced trade policy uncertainty significantly shortens unemployment duration, with hazard-rate varying across internal in-migrants and urban natives, due to variations in job accessibility and reservation wages.

A Rational Perspective Of Servant Leadership: Towards A Paradigm Shift In Servant Leader Motivation, Kevin J. Hurt, Ross Nolan

American Business Review

Advocates of servant leadership maintain that altruism is the foundational ethic fueling the success of the servant leader. Thus, the foremost requirement of a servant leader is the possession of a concern for others above and beyond his or herself. Researchers have largely neglected the possibility that servant leaders may be, at least partially, motivated by self-interest. We challenge the current foundational ethic attributed with servant leadership and put forth a new ethical perspective. Reviewing four motivational states, from purely other-centered to purely self-centered, we introduce a conceptual model and argue that the proper ethic to ascribe with servant leadership …

Harnessing Social Media For Climate Action In Developing Countries: A Case Study Of Egypt, Nicolas Hamelin, Passant Halawa

Faculty Journal Articles

Like many developing nations, Egypt is facing a climate crisis due to its agricultural dependence and the Nile Delta’s vulnerability. Despite government plans for sustainable development, recent infrastructure projects have resulted in large-scale green space removal. Effective communication about environmental issues can spark pro-environmental behavior and citizen activism. This study explores social media’s potential to bridge this gap in Egypt. Utilizing Facebook AB testing with a limited budget, we reached a significant 2.3% of Egypt’s online population (nearly 2 million users). This study explored message framing, with findings showing that rational posts resonated best while fear appeals had minimal impact. …

Maximization Of Brackish Water Productivity For The Sustainable Production Of Striped Catfish (Pangasianodon Hypophthalmus) And Grain Sorghum (Sorghum Bicolor (L.) Moench) Cultivated Under An Integrated Aquaculture–Agriculture System, Fahad Kimera, Muziri Mugwanya, Khaled Madkour, Mahmoud A.O. Dawood, Hani Sewilam

Faculty Journal Articles

Freshwater scarcity, salinity, and poor soil fertility are the major challenges affecting both food and feed productions in arid and semi-arid regions of the world. Utilization of brackish water in the production of saline-tolerant fish and valuable field crops under an integrated system is promising in the maximization of yield per crop. The aim of this study, therefore, was to (1) assess the effect of saline aquaculture wastewater on the growth, yield, forage quality, and nutritive composition of sorghum seeds and (2) assess the effect of different water qualities on the survival, growth performance, and health status of Pangasianodon hypophthalmus. …

Regulation Of Piezo Channels By Membrane Lipids, Luis Octavio Romero Garcia

Theses and Dissertations (ETD)

In cellular physiology, the transformation of energy from mechanical cues into electrical and/or chemical signals is called mechanotransduction. This ability to sense and react to external and internal mechanical forces is essential for the survival of single cell to multicellular organisms. As such, it is no surprise that mechanotransduction appeared early in the evolutionary history of life on our planet. At the cellular level, mechanotransduction is mediated by proteins and/or protein complexes that respond to mechanical stimuli in different timescales, including but not limited to changes in membrane electric potential, Ca2+ signaling, and gene expression. Among such protein complexes, mechanosensitive …

Bean 5 Turn Team: Improves Turing Interventions & Reduces Hapi Rates, Paige Thompson Rn, Johnna Grant Rn

Nurse Residency

Does implementing a turn team on hospital units aid in preventing pressure-related injuries as compared to standard of care, without a turning team?

Staff Assist Process In The Emergency Department Setting, Caroline Goodnight Rn, Rasha Burkeba Rn, William Covert Rn

Nurse Residency

In the Emergency Department, how do zone-based response systems compare to department-wide response systems in a staff assist affect overall patient outcomes within a one-year period of time?

Burnout And Work Fatigue In Contingent Faculty During The Covid-19 Pandemic, Gina Dimartino

Dissertations

The COVID-19 pandemic and immediate shift to remote learning had a major impact on faculty and students in higher education institutions (HEIs). As a result of the pandemic, many stakeholders in HEIs have experienced burnout and work fatigue, specifically, contingent/adjunct faculty. Contingent/adjunct faculty comprise a majority of faculty who serve students in colleges and universities across the country.

As the needs of students increased during the pandemic, contingent/adjunct faculty experienced increased workloads due to the additional support needed by diverse and challenged students. This further intensified the unique challenges faced by contingent faculty that existed prior to the pandemic in …

Reducing Heart Failure Readmissions, Jenny Dutra Bsn, Rn, Taylah Kilby Bsn, Rn, Carolyn Palmer Bsn, Rn

Nurse Residency

How Does Structured Nursing Led Heart Failure Education Compare to Basic Patient Education and Resources, and How Does it Influence Reducing Heart Failure Readmissions Within 30 Days of Discharge?

Psychosocial Health Of Patients With A Left Ventricular Assist Device, Sarah Christensen, Trang Le, Natalie Pagenstecher

Nurse Residency

Among adult patients diagnosed with advanced heart failure, what is the effect of left ventricular assist device (LVAD) implantation on self-reported measures of psychosocial health during the post implantation period?

Hierarchal Single-Cell Lineage Tracing Reveals Differential Fate Commitment Of Cd8 T-Cell Clones In Response To Acute Infection., Leena Abdullah

Dartmouth College Ph.D Dissertations

Generating balanced populations of CD8 effector and memory T cells is necessary for immediate and durable immunity to infections and cancer. Yet, a definitive understanding of CD8 differentiation remains unclear. Here we used CARLIN, a processive lineage recording mouse model with single-cell RNA-seq and TCR-seq to track endogenous antigen-specific CD8 T cells during acute viral infection.

Transcriptional profiling of antigen-specific T cells at the peak of the effector response to Vesicular stomatitis virus uncovered a diverse repertoire of expanded antigen-specific T-cell clones represented by seven transcriptional states. TCR enrichment analysis identified TCR clones with differential memory- or effector-fate biases during …

Primary Care Patient Interests In Joining A Planned Multi-Cancer Early Detection Clinical Trial, Ronald E. Myers, Mie Hallman, Ayako Shimada, Melissa Dicarlo, Kaitlyn V. Davis, William T. Leach, Christopher V. Chambers

Department of Medical Oncology Faculty Papers

INTRODUCTION: Clinical trials are being conducted and are being planned to assess the safety and efficacy of multi-cancer early detection (MCED) tests for use in cancer screening. This study aimed to determine the feasibility of primary care patient outreach in recruiting participants to a planned MCED clinical trial, assess patient interest in trial participation, and measure decisional conflict related to participation.

METHODS: The research team used the electronic medical record of a large, urban health care system to identify primary care patients 50-80 years of age who were potentially eligible for a planned MCED trial. We mailed information about the …

Conditional Quantization For Uniform Distributions On Line Segments And Regular Polygons, Tsianna Danielle Dominguez

Theses and Dissertations

Quantization for a Borel probability measure refers to the idea of estimating a given probability by a discrete probability with support containing a finite number of elements. If in the quantization some of the elements in the support are preselected, then the quantization is called a conditional quantization. In this thesis, we have investigated the conditional quantization for the uniform distributions defined on the unit line segments and m-sided regular polygons, where m ≥ 3, inscribed in a unit circle.

Affective Life, Mobility And Unity In U.S.-Mexico Transborder Families, Aaron A. Adame Sosa

Theses and Dissertations

There has been abundant research on transnational families and their lived realities, but most of this research focuses on analyzing family relations across long distances. This thesis examines transnational life at the borderlands and develops new frameworks for understanding family unity and separation. Using concepts from the sociology of emotions, I find that economic and opportunity inequalities structure much of transborder life and that the emotional work different family members do for the sake of their family unity is largely based on mobility privilege and the idea that the U.S. is economically better off, even as the relative poverty between …

A Historical Analysis Of Bilingual Program Implementation, Jessica Gonzalez Perez

Theses and Dissertations

The purpose of this research study was to uncover opportunities for reimagining the dual language program. Furthermore, it aims to provide valuable insights to district leaders contemplating initiating such programs. Through an examination of the program's inception and subsequent evolution, the research will offer a comprehensive understanding of its background and development. Integral to this exploration are district leaders' and campus administrators' perspectives and viewpoints directly involved in implementing the program. Their insights will shed light on the program's journey and inform potential improvements or adaptations. Ultimately, this study endeavors to serve as a roadmap for district leaders navigating the …