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Enhancing Nsclc Recurrence Prediction With Pet/Ct Habitat Imaging, Ctdna, And Integrative Radiogenomics-Blood Insights, Sheeba J Sujit, Muhammad Aminu, Tatiana V Karpinets, Pingjun Chen, Maliazurina B Saad, Morteza Salehjahromi, John D Boom, Mohamed Qayati, James M George, Haley Allen, Mara B Antonoff, Lingzhi Hong, Xin Hu, Simon Heeke, Hai T Tran, Xiuning Le, Yasir Y Elamin, Mehmet Altan, Natalie I Vokes, Ajay Sheshadri, Julie Lin, Jianhua Zhang, Yang Lu, Carmen Behrens, Myrna C B Godoy, Carol C Wu, Joe Y Chang, Caroline Chung, David A Jaffray, Ignacio I Wistuba, J Jack Lee, Ara A Vaporciyan, Don L Gibbons, John Heymach, Jianjun Zhang, Tina Cascone, Jia Wu Apr 2024

Enhancing Nsclc Recurrence Prediction With Pet/Ct Habitat Imaging, Ctdna, And Integrative Radiogenomics-Blood Insights, Sheeba J Sujit, Muhammad Aminu, Tatiana V Karpinets, Pingjun Chen, Maliazurina B Saad, Morteza Salehjahromi, John D Boom, Mohamed Qayati, James M George, Haley Allen, Mara B Antonoff, Lingzhi Hong, Xin Hu, Simon Heeke, Hai T Tran, Xiuning Le, Yasir Y Elamin, Mehmet Altan, Natalie I Vokes, Ajay Sheshadri, Julie Lin, Jianhua Zhang, Yang Lu, Carmen Behrens, Myrna C B Godoy, Carol C Wu, Joe Y Chang, Caroline Chung, David A Jaffray, Ignacio I Wistuba, J Jack Lee, Ara A Vaporciyan, Don L Gibbons, John Heymach, Jianjun Zhang, Tina Cascone, Jia Wu

Faculty, Staff and Student Publications

While we recognize the prognostic importance of clinicopathological measures and circulating tumor DNA (ctDNA), the independent contribution of quantitative image markers to prognosis in non-small cell lung cancer (NSCLC) remains underexplored. In our multi-institutional study of 394 NSCLC patients, we utilize pre-treatment computed tomography (CT) and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) to establish a habitat imaging framework for assessing regional heterogeneity within individual tumors. This framework identifies three PET/CT subtypes, which maintain prognostic value after adjusting for clinicopathologic risk factors including tumor volume. Additionally, these subtypes complement ctDNA in predicting disease recurrence. Radiogenomics analysis unveil the molecular underpinnings of these …


Promoting Participation In Individuals With Parkinson’S Disease Through The Development Of Accessible Occupation-Based Resources, Kelly Struthers Apr 2024

Promoting Participation In Individuals With Parkinson’S Disease Through The Development Of Accessible Occupation-Based Resources, Kelly Struthers

OTD Capstone Projects

This doctoral capstone project was completed through partnership with Rock Steady Boxing Music City, a non-profit organization that provides boxing classes for individuals diagnosed with Parkinson’s disease and other motor-related disorders. The purpose of this project was to understand the participatory barriers that are common within the Parkinson’s disease community and develop solution-oriented resources in response to these barriers. All developed resources were intentionally created to maximize accessibility and explored areas such as driving, fatigue, caregiving, and memory. These resources were compiled and distributed to the “fighters” of Rock Steady Boxing via an in-person “OT Corner” bulletin board, the weekly …


Supporting Adolescent Parents Involved In Younglives, Rachel Fister Apr 2024

Supporting Adolescent Parents Involved In Younglives, Rachel Fister

OTD Capstone Projects

This doctoral capstone project focused on creating educational tools and resources for adolescent caregivers, volunteer mentors, and staff associates involved in YoungLives. YoungLives is a branch of the non-profit outreach organization YoungLife, that supports adolescent/teen parents and expecting mothers worldwide. The goal of this project was to supply accessible and user-friendly resources for the population to gain knowledge on pediatric topics such as child development, age appropriate milestones, sensory processing, as well as activities to promote occupational skills. The project outcomes resulted in a guidebook and deliverables for education and training purposes, a social media platform for nationwide connection and …


Providing Sensory Integration Education And Transition Tools For The Tennessee Baptist Children’S Homes, Thuy-Duong D. Huynh Apr 2024

Providing Sensory Integration Education And Transition Tools For The Tennessee Baptist Children’S Homes, Thuy-Duong D. Huynh

OTD Capstone Projects

This doctoral capstone project was completed through a partnership with the residential department of the Tennessee Baptist Children’s Homes, a state-wide ministry that cares for children whose families are in crisis. There were two primary focuses for this project: (1) providing sensory integration education to house parents and (2) creating tools to ease transitions. Outcomes included a presentation and training on sensory integration, a booklet with easily accessible sensory integration information, a local activity guide for day visits with families, and a routine schedule of home visits to ease transitions.


Housing Rights Fair, Housing Rights Clinic Apr 2024

Housing Rights Fair, Housing Rights Clinic

Housing Rights Clinic

April 11, 2024


Housing Rights Fair, Nyls Housing Rights Clinic Apr 2024

Housing Rights Fair, Nyls Housing Rights Clinic

Housing Rights Clinic

April 11, 2024


United: Sun, Moon And Us, Eric F. Spina Apr 2024

United: Sun, Moon And Us, Eric F. Spina

President's Blog: From the Heart

The University of Dayton cancelled afternoon classes on Monday. Well, not exactly. The Central Mall, dotted with students, faculty, staff and families sprawled on blankets, turned into a massive outdoor laboratory for viewing the moon move across the sun and cast the University into twilight and then near-darkness.


2024 Undergraduate Research Symposium Program, Coastal Carolina University Apr 2024

2024 Undergraduate Research Symposium Program, Coastal Carolina University

Undergraduate Research Symposium Programs

15th Annual Undergraduate Research Symposium, April 10-11, 2024.


Engineering Mesenchymal Stromal Cells To Suppress Inflammation And Increase Beta-Cell Mass For Treating Type 1 Diabetes, Dhruva Patel Apr 2024

Engineering Mesenchymal Stromal Cells To Suppress Inflammation And Increase Beta-Cell Mass For Treating Type 1 Diabetes, Dhruva Patel

MUSC Theses and Dissertations

Type 1 diabetes (T1D) is a life-threatening autoimmune disease where the immune system destroys the insulin producing beta-cells in the pancreas. There is no cure for the disease, and the current treatment involves life-long, daily injection of insulin. An ideal therapy for T1D will be the suppression of autoimmunity and increased functional beta-cell mass. The immune regulatory cytokine IL10 can suppress inflammation in various autoimmune diseases. On the other hand, several growth factors and peptide hormones are known to promote an increase in beta-cell mass, through neogenesis and beta-cell proliferation. However, efficient induction of increased beta-cell mass requires preferential and …


The George-Anne Daily, Georgia Southern University Apr 2024

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Chhs Graduate Programs Make Nation's Top 100, Jill Buchanan Apr 2024

Chhs Graduate Programs Make Nation's Top 100, Jill Buchanan

UNH Today Archive

No abstract provided.


Pharmacies Could Create Custom Drugs With 3d-Printed Medication, Clara Turnage Apr 2024

Pharmacies Could Create Custom Drugs With 3d-Printed Medication, Clara Turnage

University of Mississippi News

OXFORD, Miss. – More than 40% of older Americans take five or more prescription drugs a day, and nearly 20% take 10 or more. What if there was a way to combine those medications into one easy-to-track pill?


Real-Time Vehicle And Lane Detection Using Modified Overfeat Cnn: A Comprehensive Study On Robustness And Performance In Autonomous Driving, Monowar Hossain Saika, Sonjoy Paul Avi, Kazi Toriqul Islam, Tanjida Tahmina, Md Shahriar Abdullah, Touhid Imam Apr 2024

Real-Time Vehicle And Lane Detection Using Modified Overfeat Cnn: A Comprehensive Study On Robustness And Performance In Autonomous Driving, Monowar Hossain Saika, Sonjoy Paul Avi, Kazi Toriqul Islam, Tanjida Tahmina, Md Shahriar Abdullah, Touhid Imam

Civil Engineering Faculty Publications

This examination researches the use of profound learning methods, explicitly utilizing Convolutional Brain Organizations (CNNs), for ongoing recognition of vehicles and path limits in roadway driving situations. The study investigates the performance of a modified Over Feat CNN architecture by making use of a comprehensive dataset that includes annotated frames captured by a variety of sensors, including cameras, LIDAR, radar, and GPS. The framework shows heartiness in identifying vehicles and anticipating path shapes in 3D while accomplishing functional rates of north of 10 Hz on different GPU setups. Vehicle bounding box predictions with high accuracy, resistance to occlusions, and efficient …


The Current - Volume 34 Issue 12, Nova Southeastern University Apr 2024

The Current - Volume 34 Issue 12, Nova Southeastern University

Student Newspapers

No abstract provided.


Jazz & Contemporary Combos, Department Of Music, University Of Richmond Apr 2024

Jazz & Contemporary Combos, Department Of Music, University Of Richmond

Music Department Concert Programs

No abstract provided.


Mindfulness Exercises For Educators, Eric B. Miller Apr 2024

Mindfulness Exercises For Educators, Eric B. Miller

Open Educational Resources

This compilation of mindfulness exercises includes a curated selection of online resources, as well as mindfulness exercises description generated via prompt to ChatGPT 3.5.


How The Arts Benefit The Whole Child, Sophie Rose Fudim Apr 2024

How The Arts Benefit The Whole Child, Sophie Rose Fudim

Whittier Scholars Program

This literature review draws on insights from scholars and arts advocates, it delves into the significance of incorporating artistic practices in schools and advocates for including arts education in public schools. This literature review utilizes studies, peer-reviewed research papers, and governmental recommendations based on current research. Art has a highly transformative power. It benefits the development of complex thought processes and offers insights into children's abilities. By integrating art into education, educators can address the evolving challenges of early childhood education and cultivate environments where students can be engaged by enthusiastic, trained teachers and get excited about learning. Art prepares …


Clarinet Community Concert, Arkansas State University Department Of Music Apr 2024

Clarinet Community Concert, Arkansas State University Department Of Music

Performance Programs

No abstract provided.


Framing Contestation And Public Influence On Policymakers: Evidence From Us Artificial Intelligence Policy Discourse, Daniel S. Schiff Apr 2024

Framing Contestation And Public Influence On Policymakers: Evidence From Us Artificial Intelligence Policy Discourse, Daniel S. Schiff

Purdue University Libraries Open Access Publishing Fund

As artificial intelligence (AI) policy has begun to take shape in recent years, policy actors have worked to influence policymakers by strategically promoting issue frames that define the problems and solutions policymakers should attend to. Three such issue frames are especially prominent, surrounding AI’s economic, geopolitical, and ethical dimensions. Relatedly, while technology policy is traditionally expert-dominated, new governance paradigms are encouraging increased public participation along with heightened attention to social and ethical dimensions of technology. This study aims to provide insight into whether members of the public and the issue frames they employ shape—or fail to shape—policymaker agendas, particularly for …


The Effects Of Neuromuscular Electrical Stimulation On Chronic Dysphagia Following Anterior Cervical Disc Fusion Surgery: A Case Report, Anna Munson Apr 2024

The Effects Of Neuromuscular Electrical Stimulation On Chronic Dysphagia Following Anterior Cervical Disc Fusion Surgery: A Case Report, Anna Munson

Honors Theses

Background: Current literature is lacking an understanding of the physiological mechanisms underlying dysphagia (impairment in swallowing function) that manifests as the result of anterior cervical discectomy and fusion (ACDF). ACDF is a common cervical spinal procedure that, due to its anterior to posterior (front-to-back) approach, risks significant injury to the larynx, which is critical for swallowing food and liquid safely. Furthermore, the general therapeutic approaches available to individuals with dysphagia after ACDF lack specificity of what is being targeted (Ko, et al. 2022). This project is a single subject case report of an individual who underwent ACDF and received neuromuscular …


The Effects Of Therapy Dogs On Students, Chloe Romack Apr 2024

The Effects Of Therapy Dogs On Students, Chloe Romack

Honors Theses

This thesis explores the effects therapy dogs have on students. It begins with a literature review of 17 articles that involve animal-assisted interventions with students and children. The main topics covered include the definition of a therapy animal and how dogs can influence learning, socialization, emotional well-being, anxiety, and depression. It also discusses how dogs can be used in therapy and special education classrooms as well as the major concerns of dogs in schools. Drawing upon the previous research, a survey was sent to school staff in the Paw Paw Public School District. The participants of this study consisted of …


The Economics Of Interdependencies Between People And Environment, Sustainability Institute Apr 2024

The Economics Of Interdependencies Between People And Environment, Sustainability Institute

Sustainability Institute Blog

No abstract provided.


Virtual Gaming, Actual Damage: Video Game Design That Intentionally And Successfully Addicts Users Constitutes Civil Battery, Allison Caffarone Apr 2024

Virtual Gaming, Actual Damage: Video Game Design That Intentionally And Successfully Addicts Users Constitutes Civil Battery, Allison Caffarone

Duke Law & Technology Review

In recent years, there has been increased academic interest in both the neurological effects of compulsive gaming and the potential tort liability of game developers who scientifically engineer games in order to addict users. Scholars from various disciplines are currently debating the scope and potential solutions to the problems associated with Gaming Disorder, now a globally recognized illness. This article contributes to this discussion by offering a multidisciplinary analysis of the scope of video game addiction, its neurological bases, and its relation to the legal rights and responsibilities of victims and game developers. In addition, this article explores the practical …


Protecting American Children: A Social-Ecological Analysis Of Pactp4, Julia Rossmiller Apr 2024

Protecting American Children: A Social-Ecological Analysis Of Pactp4, Julia Rossmiller

Student Works

The quantity of pesticides used annually in the United States exceeds one billion pounds every year, and the amount is only rising. The current law that governs the use of pesticides—The Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), permits the use of 72 known pesticides that have been proven harmful and are banned in other countries. Research links the usage of pesticides to the health of individuals, families, and whole communities within the environment. Moreover, dangerous pesticides have been shown to disproportionately affect children, agricultural workers, people of color, and low-income communities. Despite the mounting evidence that confirms the adverse …


Shared Genomic Segments Analysis Identifies Mhc Class I And Class Iii Molecules As Genetic Risk Factors For Juvenile Idiopathic Arthritis, Cecile N. Avery, Nicole D. Russell, Cody J. Steely, Aimee O. Hersh, John F. Bohnsack, Sampath Prahalad, Lynn B. Jorde Apr 2024

Shared Genomic Segments Analysis Identifies Mhc Class I And Class Iii Molecules As Genetic Risk Factors For Juvenile Idiopathic Arthritis, Cecile N. Avery, Nicole D. Russell, Cody J. Steely, Aimee O. Hersh, John F. Bohnsack, Sampath Prahalad, Lynn B. Jorde

Markey Cancer Center Faculty Publications

Juvenile idiopathic arthritis (JIA) is a complex rheumatic disease encompassing several clinically defined subtypes of varying severity. The etiology of JIA remains largely unknown, but genome-wide association studies (GWASs) have identified up to 22 genes associated with JIA susceptibility, including a well-established association with HLA-DRB1. Continued investigation of heritable risk factors has been hindered by disease heterogeneity and low disease prevalence. In this study, we utilized shared genomic segments (SGS) analysis on whole-genome sequencing of 40 cases from 12 multi-generational pedigrees significantly enriched for JIA. Subsets of cases are connected by a common ancestor in large extended pedigrees, increasing the …


Review Of Methodological Decisions In Life Cycle Assessment (Lca) Of Biorefinery Systems Across Feedstock Categories, James Gaffey, Maurice N. Collins, David Styles Apr 2024

Review Of Methodological Decisions In Life Cycle Assessment (Lca) Of Biorefinery Systems Across Feedstock Categories, James Gaffey, Maurice N. Collins, David Styles

Publications

The application of life cycle assessment (LCA) to biorefineries is a necessary step to estimate their environmental sustainability. This review explores contemporary LCA biorefinery studies, across different feedstock categories, to understand approaches in dealing with key methodological decisions which arise, including system boundaries, consequential or attributional approach, allocation, inventory data, land use changes, product end-of-life (EOL), biogenic carbon storage, impact assessment and use of uncertainty analysis. From an initial collection of 81 studies, 59 were included within the final analysis, comprising 22 studies which involved dedicated feedstocks, 34 which involved residue feedstocks (including by-products and wastes), and a further 3 …


Identifying A Group Of Factors Predicting Cognitive Impairment Among Older Adults, Longgang Zhao, Yuan Wang, Eric Mishio Bawa, Zichun Meng, Jingkai Wei, Sarah Newman-Norlund, Tushar Trivedi, Hatice Hasturk, Roger Newman-Norlund, Julius Fridriksson Ph.D., Anwar T. Nerchant Apr 2024

Identifying A Group Of Factors Predicting Cognitive Impairment Among Older Adults, Longgang Zhao, Yuan Wang, Eric Mishio Bawa, Zichun Meng, Jingkai Wei, Sarah Newman-Norlund, Tushar Trivedi, Hatice Hasturk, Roger Newman-Norlund, Julius Fridriksson Ph.D., Anwar T. Nerchant

Faculty Publications

Background

Cognitive impairment has multiple risk factors spanning several domains, but few studies have evaluated risk factor clusters. We aimed to identify naturally occurring clusters of risk factors of poor cognition among middle-aged and older adults and evaluate associations between measures of cognition and these risk factor clusters.

Methods

We used data from the National Health and Nutrition Examination Survey (NHANES) III (training dataset, n = 4074) and the NHANES 2011–2014 (validation dataset, n = 2510). Risk factors were selected based on the literature. We used both traditional logistic models and support vector machine methods to construct a composite score …


Factors Affecting Honey Bee (Apis Mellifera L.) Health As Perceived By South Georgia Commercial Beekeepers, Kimberly Post Apr 2024

Factors Affecting Honey Bee (Apis Mellifera L.) Health As Perceived By South Georgia Commercial Beekeepers, Kimberly Post

Journal of Extension

Honey bees (Apis mellifera L.) are critical to the pollination of many crops. Bee-oriented organizations survey beekeepers annually to gather information about colony loss and contributing factors. Unfortunately, these surveys provide insufficient data from sideliner and commercial beekeepers in Georgia. Through a survey to better understand South Georgia beekeepers’ perceptions of honey bee health, this project engaged a previously underrepresented group of sideliner and commercial beekeepers.


Baccalaureate Nurses' Experiences And Understanding Of Adults Living With Sickle Cell Disease, Shelia A. Reid Apr 2024

Baccalaureate Nurses' Experiences And Understanding Of Adults Living With Sickle Cell Disease, Shelia A. Reid

Dissertations

Background: Sickle cell disease (SCD) is a chronic, genetic blood disorder with most treatment interventions geared toward the acute phase of the disease, which often leads to fragmented care. In Canada, the teaching of SCD occurs without a genetic competency, resulting in miscommunication, misunderstanding, and inadequate nursing care.

Purpose: This investigator examined baccalaureate nurses' experiences and understanding of working with adults living with SCD.

Methods: A semi-structured interview guide was used to explore baccalaureate nurses' experiences and understanding of working with young adults living with SCD.

Results: Lindseth and Norbergs' (2004) interpretation of Ricoeur's hermeneutic interpretative phenomenological approach was used …


2024 Conference Program, Georgia Southern University Apr 2024

2024 Conference Program, Georgia Southern University

South East Coastal Conference on Languages & Literatures (SECCLL)

2024 Conference Program