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Cas Connections- 2024 Spring Term - April, Dean's Office College Of Arts And Science

CAS Connections

No abstract provided.

General Non-Destructive Evaluation For Friction Stir Welding, Johnathon Bryce Hunt

Theses and Dissertations

Friction stir welding (FSW) is an advantageous solid state joining method for many different engineering designs. It was invented in 1991 by TWI and since that time a tremendous amount of research has been executed to understand and implement FSW in a myriad of materials in numerous industries such as aerospace, ship building, train, automotive, energy, agriculture and others. Most industries have strict weld inspection processes to validate a weld before it is put into service. One of the main weld characteristics that is measured is the size of any subsurface volumetric voids. The current standard to test friction stir …

Application Of The Immobilized Low-Activity Waste Glass Corrosion Model To The Static Dissolution Of 24 Statistically-Designed Alkali-Borosilicate Waste Glasses, Sebastien N. Kerisit, James J. Neeway, Charmayne E. Lonergan, Benjamin Parruzot, Jarrod V. Crum, Richard C. Daniel, Gary L. Smith, R. Matthew Asmussen

Materials Science and Engineering Faculty Research & Creative Works

Glass corrosion models that capture the complex mechanisms of the glass-water reaction enable the prediction of nuclear waste glass durability in disposal scenarios. Parameterization of such models is challenging because of the need to capture changes in corrosion behavior with time, reaction conditions, and glass composition. Here, we describe and employ the ILAW (immobilized low-activity waste) glass corrosion model (IGCM) in geochemical simulations of static dissolution tests, at two temperatures (40 °C and 90 °C), for a matrix of 24 enhanced low-activity waste (eLAW) glasses statistically designed to cover a processable composition space defined by 8 major glass components (Al …

The Study On Mechanical Model Considering Optimal Self-Adaption In The Bottleneck Area, Longcheng Yang, Huajun Wang, Jun Hu, Hongyu Pan, Juan Wei, Lei You, Hao Zhang, Junxi Wang

Faculty, Staff and Student Publications

It aims to solve the problem that the evacuation state of pedestrians depicted by the traditional social force model in a crowded multiexit scenario has a relatively large difference with the actual state, especially the 'optimal path' considered by the self-driving force is the problem of shortest path, and the multiexit evacuation mode depicted by the 'herd behavior' is the local optimum problem. Through in-depth analysis of actual evacuation data of pedestrians and causes of problem, a new crowd evacuation optimization model is established in order to effectively improve the simulation accuracy of crowd evacuation in a multi-exit environment. The …

Multi-Omics Analysis Reveals Immune Features Associated With Immunotherapy Benefit In Patients With Squamous Cell Lung Cancer From Phase Iii Lung-Map S1400i Trial, Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W Redman, Hong Chen, Ganiraju C Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E Gray, Roy S Herbst, Ignacio I Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J Jack Lee, Jianjun Zhang, Cara Haymaker

Faculty, Staff and Student Publications

PURPOSE: Identifying molecular and immune features to guide immune checkpoint inhibitor (ICI)-based regimens remains an unmet clinical need.

EXPERIMENTAL DESIGN: Tissue and longitudinal blood specimens from phase III trial S1400I in patients with metastatic squamous non-small cell carcinoma (SqNSCLC) treated with nivolumab monotherapy (nivo) or nivolumab plus ipilimumab (nivo+ipi) were subjected to multi-omics analyses including multiplex immunofluorescence (mIF), nCounter PanCancer Immune Profiling Panel, whole-exome sequencing, and Olink.

RESULTS: Higher immune scores from immune gene expression profiling or immune cell infiltration by mIF were associated with response to ICIs and improved survival, except regulatory T cells, which were associated with worse …

Safety Profile And Adverse Event Management For Futibatinib, An Irreversible Fgfr1-4 Inhibitor: Pooled Safety Analysis Of 469 Patients, Funda Meric-Bernstam, Antoine Hollebecque, Junji Furuse, Do-Youn Oh, John A Bridgewater, Masashi Shimura, Bailey Anderson, Nanae Hangai, Volker Wacheck, Lipika Goyal

Faculty, Staff and Student Publications

PURPOSE: Futibatinib, a covalently-binding inhibitor of fibroblast growth factor receptor (FGFR)1-4 gained approval for the treatment of refractory, advanced intrahepatic cholangiocarcinoma (iCCA) harboring an FGFR2 fusion/other rearrangement. An integrated analysis was performed to evaluate safety and provide guidance on the management of futibatinib-associated adverse events (AEs) in patients with unresectable/metastatic tumors, including iCCA.

PATIENTS AND METHODS: Data from three global phase I or II studies of futibatinib (NCT02052778; JapicCTI-142552) were pooled. AEs were graded per NCI CTCAE v4.03, where applicable. Safety was analyzed for patients receiving any futibatinib starting dose (overall population) and in those receiving the approved starting dose …

Applying The Consumer Decision-Making Model To An On-Campus Coffee Shop, Madalynne Chapman

Honors Projects

The purpose of this research was to use the consumer decision-making model as a framework to assess if there are factors that may prompt (or not prompt) an individual to make a purchase at Forhan’s Café, a small coffee shop located inside of the Maurer Center at Bowling Green State University. To answer this, both a personal interview with a BGSU Dining staff member and an online survey of campus consumers were conducted. The personal interview was conducted to understand their current marketing strategies for the café and to guide the survey design. The online survey consisted of 24 questions …

Clarice Lispector: From Brazil To The World, Earl Fitz

Purdue Studies in Romance Literatures

Clarice Lispector: From Brazil to the World explains why the Brazilian master was so transformative of modern Brazilian literature and why she has become such a celebrity in the world literature arena. This book also shows why Lispector is not one writer, as many think, but many writers. By offering close readings of her novels, stories, and nonfiction pieces, Earl E. Fitz shows the diverse sides of her literary world. Chapters cover Lispector’s devotion to language and its connection to identity; her political engagement; and her humor, eroticism, and struggle with the concept of God. The last chapter seeks to …

Finite Rigid Sets In Sphere Complexes, Edgar A. Bering, Christopher J. Leininger

Faculty Research, Scholarly, and Creative Activity

A subcomplex X≤C of a simplicial complex is strongly rigid if every locally injective, simplicial map X→C is the restriction of a unique automorphism of C. Aramayona and the second author proved that the curve complex of an orientable surface can be exhausted by finite strongly rigid sets. The Hatcher sphere complex is an analog of the curve complex for isotopy classes of essential spheres in a connect sum of n copies of S1×S2. We show that there is an exhaustion of the sphere complex by finite strongly rigid sets for all n≥3 and that when n=2 the sphere complex …

Influence Of Eco-Friendly Agar-Derivatives On The Electrochemical Performance Of Carbon Felts Electrodes Of Vanadium Redox Flow Battery, Abdulmonem Fetyan, Ayoob Alhammadi, Zineb Matouk, Anugrah Andisetiawan, Ahmed Bahaa

All Works

In this study, bio-derived natural agar powder was used as an electrocatalyst for application as an electrode in all‑vanadium redox flow batteries. Different concentrations of agar solution were tested, and cyclic voltammetry studies confirmed that agar loaded felts have good catalytic activity toward both redox couples V4+/V5+ at the positive and V2+/V3+ at the negative side. Energy dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy demonstrated the presence of higher amount of oxygen-functional groups on the surface of the fibers. Contact angle measurements demonstrated an enormous increase in hydrophilicity of the felts treated with agar. Long-term charge/discharge profiles revealed 6 % …

Modelling The Building-Related Photovoltaic Power Production Potential In The Light Of The Eu's Solar Rooftop Initiative, Gergely Molnár, Luisa F. Cabeza, Souran Chatterjee, Diana Ürge-Vorsatz

School of Geography, Earth and Environmental Sciences

Decarbonizing the building sector is key to meet the EU climate goals by 2050. Although the recent policies recognized the importance of on-site solar energy production in the energy transition, there are only a few modelling studies analyzing how much the gap between the technically possible and policy-driven power generation of rooftop photovoltaic (PV) panels can be reduced. This study, therefore, uses geospatial techniques and the high-resolution Building Integrated Solar Energy (BISE) supply model to estimate the main spatial and temporal characteristics of the rooftop PV energy production potential. To support decision-making, important implications of the Solar Rooftop Initiative action …

China Maritime Report No. 37: Re-Engaging With The World: China's Military Diplomacy In 2023, Jie Gao, Kenneth W. Allen

CMSI China Maritime Reports

China’s military diplomacy plays a crucial role in advancing the nation's foreign policy objectives and safeguarding its strategic interests. This report highlights a diverse array of activities within military diplomacy, including senior-level meetings, joint military exercises, naval port calls, UN peacekeeping operations, and academic exchanges. Our findings reveal a significant—but incomplete—recovery in China's military diplomacy activities in 2023, following a period of reduced contacts with foreign militaries during the COVID-19 pandemic. Southeast Asia and Russia remain primary partners for China, with emerging strategic importance also seen in Africa, Oceania, and the Middle East. Overall, China's military diplomacy underscores its efforts …

The Role Internships Play In Political Science Education, Madaline Lankford

Honors Theses

This project will explore the critical role internships play in undergraduate education, with a particular focus on political science, by examining the history and impact of Western Michigan University’s Capital Internship Program. The study aims to shed light on the diverse experiences of past participants and conduct comprehensive research into the significance of internships in shaping the academic and professional trajectories of countless students. By delving into the stories and reflections of former interns, this research will provide testimonials that underscore the value of experiential learning. These personal accounts will highlight how internships bridge the gap between theoretical knowledge acquired …

State Of Utah, Plaintiff/ Appellee V. Cory Jason Thomas, Defendant/ Appellant : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

On appeal from the Second Judicial District Court, Weber County, Honorable Judge Hyde, District Court No. 211900875

Christopher F. Allred, Benjamin Gabbert, Counsel for Appellee

Hannah Leavitt-Howell, Jessica Hyde Holzer, Counsel for Appellant

Trisha Dawn Small, Appellee/Petitioner And, Nathan Dale Small., Appellant/Respondent: Brief Of Appellee, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

INTERLOCUTORY APPEAL FROM THE FIRST DISTRICT COURT. BOX ELDER COUNTY, STATE OF UTAН THE HONORABLE SPENCER WALSIH, PRESIDING

Jeremy G. Jones, Attorney for Respondent/Appellant

Michael E. Christiansen, Attorney for Petitioner/Appellee

Excellence Summit 2024, Office Of Research And Sponsored Projects Operations

Excellence Summit (Research Week) Archived Proceedings

In it's 17th year, the University of the Incarnate Word, welcome all to read and review the proceedings of the annual research week. The 2024 Excellence Summit highlighted academic excellence across all schools featuring topics from nutrition studies to soil amendments, artificial intelligence, medical case studies, and music composition studies. The rich mixture of humanities, health sciences, physical sciences, education, and business can be found in this booklet. We thank all that contributed to these works and hope the community enjoys learning from today's and tomorrow's leaders in research, inquiry, and scholarship.

Mcl-1 Mediates Intrinsic Resistance To Raf Inhibitors In Mutant Braf Papillary Thyroid Carcinoma, Maria Cavallo, Jacob Yo, Kayla Gallant, Camille Cunanan, Amirali Amirfallah, Marzieh Daniali, Alyssa Sanders, Andrew Aplin, Edmund Pribitkin, Edward Hartsough

Kimmel Cancer Center Faculty Papers

Papillary thyroid carcinoma (PTC) is the most frequent form of thyroid cancer. PTC commonly presents with mutations of the serine/threonine kinase BRAF (BRAF^V600E), which drive ERK1/2 pathway activation to support growth and suppress apoptosis. PTC patients often undergo surgical resection; however, since the average age of PTC patients is under 50, adverse effects associated with prolonged maintenance therapy following total thyroidectomy are a concern. The development of mutant-selective BRAF inhibitors (BRAFi), like vemurafenib, has been efficacious in patients with metastatic melanoma, but the response rate is low for mutant BRAF PTC patients. Here, we assay the therapeutic response …

On Learning Your Gender: A Comprehensive View, Audra M. Hazelwood

Theses

This essay provides a metaphysical and epistemological account of gender. The metaphysics involves a ‘non-reductionist view of gender’, which is to say that gender cannot be reduced to a single factor. On this view gender begins with one’s innate gender inclinations (in the vein of Julia Serano). These inclinations pick out a specific range of gender possibilities from the gender spectrum that apply to a person. At the same time we live in communities and cultures with certain gender norms. This is where epistemology comes into play since our gender inclinations are filtered through gender norms and some people are …

Friction Stir Welding Of Tube-To-Tubesheet And Spot Joints For Virgin And Recycled Thermoplastic Materials., Syed Haris Iftikhar

Thesis/ Dissertation Defenses

Thermoplastic materials are becoming popular, due to their chemically inert and anti-fouling properties, for use in industrial heat exchanger applications involving heating/cooling of highly reactive fluids like acids. A novel nonconventional joining framework, based on the friction stir welding (FSW) technique, is developed to create high-quality thermoplastic tube-to-tubesheet joints (TTJs). The proposed technique has applications in the thermoplastic shell-andtube heat exchanger and piping industries (as flange-to-pipe joints). The primary objective is to study the feasibility of the FSW technique for developing thermoplastic TTJs, followed by optimization of the process parameters and detailed material characterizations. This work used workpieces (tube, tubesheet) …

The Person Experiences Interview Survey: A Measure Addressing Ableism In Mental Healthcare For Patients With Intellectual And Developmental Disabilities, Micah Peace Urquilla

Institute on Disability

Many People with Intellectual and Developmental Disabilities (IDD) also have mental health needs requiring the support of mental health service providers, yet they may experience barriers to full engagement in their care due to ableism. Ableism is a kind of prejudice that impacts People with IDD in many parts of life, even in mental health care. This article proposes how an adapted Patient Reported Experience Measure (PREM) can be a response to ableism, with an impact at three distinct yet interrelated levels that reflect the parties involved in the mental healthcare of People with IDD-MH: provider, caregiver, and patient.

At …

Interpersonal Violence And The Impact On Children’S Educational Outcomes, Samantha Hurst

Senior Capstone Papers

This capstone explores the complex topic of interpersonal violence which impacts children in the home and their school outcomes. Understanding children who are not getting their emotional or physical needs met could have a harder time focusing, staying awake, or being present in the classroom is incredibly important. This paper examines the pre-existing literature on the topic of how children react to interpersonal violence and how punishment in schools can affect academic outcomes. A solution is proposed for teachers to be taught trauma informed care to increase empathy towards students and decrease behavioral suspensions. Trauma informed care can mitigate partial …

Social Emotional Learning For Students In Schools And Communities, Gisselle Villar

Senior Capstone Papers

The goal of the educational approach known as Social and Emotional Learning (SEL) is to integrate these skills regarding SEL to be implemented in the school curriculum. In addition to emphasizing students’ abilities, education helps students build the kind of brains needed to acquire everyday tasks. The goal of this proposal is to help students develop a feeling of self-worth and awareness so they can connect and communicate honestly with one another. Schools will witness a significant shift in the lives of their students and the way teachers instruct once this learning is implemented. When this knowledge is successfully applied …

Jason D. Phillips Cv, Jason D. Phillips

Libraries' Documents

No abstract provided.

Ndls Communicator: Week Of 04.15.24, Notre Dame Law School

NDLS Communicator

The Latest News

• Notre Dame Law School strengthens international ties with MOUs with Panthéon-Assas and Lucerne
• Prof. Robert P. Thompson Shares Insights on Securities Law at ND Law Patricia O'Hara Distinguished Lecture in Law & Business
• Notre Dame Law School holds third annual Interfaith Dinner in observance of Passover, Easter, Ridván, and Ramadan
• On April 11 and 12, Jay Tidmarsh participated in two panels at a conference organized by the James Humphreys Complex Litigation Center at George Washington University Law School.
• Mary Ellen O'Connell was quoted in an article by Morningstar Online, "Nicaragua takes Germany to top UN court seeking …

Clearing The Air: Innovations In Imaging For Early Detection And Management Of Chronic Obstructive Pulmonary Disease, Francesca Polverino

Faculty, Staff and Students Publications

No abstract provided.

Refractory Chronic Spontaneous Urticaria After Heterologous Covid-19 Booster Vaccination, Miranda Crista Tomaras, Leah Michelle Douglas, Rosa Michelle Schmidt, Maria Suzanne Bloomquist, Abdul Hafeez Diwan, Soo Jung Kim

Faculty, Staff and Students Publications

Chronic spontaneous urticaria (CSU) involves recurrent, pruritic wheals lasting more than 6 weeks in response to various etiologies, including unknown causality. Though most cutaneous reactions to the COVID-19 vaccine series are self-limited and of short duration, more complex presentations including chronic spontaneous urticaria have been described. To the best of our knowledge, this is the first report of chronic spontaneous urticaria following heterologous mRNA COVID-19 booster vaccination that includes vaccination with both forms of the mRNA vaccine. Our patient received Pfizer-BioNTech for the primary series and Moderna for the booster. After failing several therapies, our patient's urticaria was refractory even …

448-452 W. 57 Assoc. Llc V. Ghali

All Decisions

The landlord sued the tenant for non-payment of rent, but the court dismissed the case because the landlord's demand for rent was based on an invalid lease agreement. The court ruled that a non-payment proceeding requires a valid agreement, express or implied, to pay the rent demanded and that the rent demand must specify the exact amount owed for each period.

Microcapsule Transport And Blockage In Rough-Walled Fractures, Brittney Diana Seaburn

Civil Engineering ETDs

Thermal short-circuiting is a potential problem for Enhanced Geothermal Systems (EGS). One solution to this problem is to reduce the permeability of very conductive fractures with thermally degradable microcapsules carrying porous polymers that bond to rock, reducing fluid flow without completely sealing the fracture. This concept requires microcapsules to principally travel in the larger, problematic fractures, minimizing entry into smaller fractures; consequently, understanding the transport and blockage of microcapsules is critical. Using a flow visualization configuration, this study involved quantifying the transport and blockage of microcapsules in transparent fracture replicas. Analyses determined most blockage occurred in regions with local apertures …

Students Step Up To The Plate At Sports Career Fair, Aaron Sanborn

UNH Today Archive

No abstract provided.

Flynn Fellowship To Jumpstart Student's Nursing Career, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.