Digital Commons Network^™

Entrepreneur Ready To Mass-Produce Eye Movement Recording System Thanks To Engineering Senior Design Teams, University Of Dayton

Blog: The Dayton Engineer

Ron Waldorf always had an interest in how and why our eyes move. He was the first to develop and receive funding for the use of infrared computer image processing of eye movements for vestibular function medical applications — vertigo, dizziness, associated brain tumors — that affect our sense of balance.

Fsec Meeting Minutes April 12, 2024, University Of Rhode Island Faculty Senate

Faculty Senate Executive Committee Minutes

No abstract provided.

Volume Cxliii, Number 18, April 12, 2024, Lawrence University

The Lawrentian

No abstract provided.

Mathematically Rigorous Deep Learning Paradigms For Data-Driven Scientific Modeling, Owen Nicholas Davis

Mathematics & Statistics ETDs

This dissertation explores the crucial role of data-driven modeling in science and engineering, with a focus on developing surrogate models to accelerate large-scale computational tasks, aiding in both outer-loop functions like uncertainty quantification and expensive inner-loop tasks within broader computational frameworks. Challenges arise with increased problem dimension and sparse, noisy training data, particularly significant when constructing surrogates for very expensive computational models where acquiring sufficient high-fidelity training data is unfeasible. In such scenarios, training surrogates from an ensemble of multifidelity information sources of varying accuracy and cost becomes essential. We emphasize neural network-based modeling paradigms, which are flexible in integrating …

Role Of Protein Kinase A And A Kinase Anchoring Proteins In Buffering And Compartmentation Of Camp Signalling In Human Airway Smooth Muscle Cells, Rinzhin T. Sherpa, Karni S. Moshal, Shailesh R. Agarwal, Rennolds S. Ostrom, Robert D. Harvey

Pharmacy Faculty Articles and Research

Background and Purpose

In human airway smooth muscle (hASM) cells, not all receptors stimulating cAMP production elicit the same effects. This can only be explained if cAMP movement throughout the cell is restricted, yet the mechanisms involved are not fully understood. Phosphodiesterases (PDEs) contribute to compartmentation of many cAMP responses, but PDE activity alone is predicted to be insufficient if cAMP is otherwise freely diffusible. We tested the hypothesis that buffering of cAMP by protein kinase A (PKA) associated with A kinase anchoring proteins (AKAPs) slows cAMP diffusion and that this contributes to receptor-mediated, compartmentalized responses.

Experimental Approach

Raster image …

Mahesh Julka V. Attorney General United States Of America

2024 Decisions

Agency

Usa V. Raymond Petway

2024 Decisions

USDC for the District of New Jersey

Usa V. Carlos Hill

2024 Decisions

USDC for the Middle District of Pennsylvania

Usa V. Carlos Hill

2024 Decisions

USDC for the Middle District of Pennsylvania

In Re: Mitchell Nicholas

2024 Decisions

USDC for the District Court of the Virgin Islands

Raymond Johnson V. Warden Allenwood Fci

2024 Decisions

USDC for the Middle District of Pennsylvania

Hayriye Gok V. Usa

2024 Decisions

USDC for the Eastern District of Pennsylvania

Philip Siegel V. Mark Goldstein

2024 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. Dennis Davis

2024 Decisions

USDC for the Eastern District of Pennsylvania

Gardner-Webb Supporters Surpass Double Dawg Day Records With $1.4 Million Raised, Office Of University Communications

Gardner-Webb NewsCenter Archive

Faithful supporters answered the call in a big way on Gardner-Webb University’s ninth annual Double Dawg Day, April 11, setting new and impressive records for The one-day fundraising total reached its highest dollar amount ever — $1.4 million. New heights were also reached when GWU recorded the greatest number of gifts received in a single day and when the donor map for the first time included contributors residing in every U.S. state.

Unpacking Automated Test Assembly: New Findings And Directions For The Future, Ling Tan, Charlotte Waters, Fuchan Huang, Dan Cloney

OECD Programme for International Student Assessment (PISA)

In large-scale assessments, the manual assembly of tests to meet many competing criteria may become an intractable task. Automated test assembly (ATA) can use optimisation algorithms to achieve optimal assembly outcomes. Since 2018, PISA has been transitioning from fixed test forms to adaptive testing. This transition is driven by the aim of improved test targeting, which increases reliability. Multi-stage adaptive testing (MSAT) has been preferred to item level computer adaptive testing (CAT) as it can better address the sometimes-competing requirements of an assessment like PISA where item exposure, position effects, construct coverage, and cross-sectional trend all must be met in …

Emerging Therapies For Glioblastoma, Stella Aime Rios, Stephanie Oyervides, David Uribe, Angelica Maree Reyes, Victor Fanniel, Jonathan Vazquez, Megan Keniry

School of Integrative Biological & Chemical Sciences Faculty Publications

Simple Summary

Glioblastoma is the most common malignant brain cancer and is associated with poor prognosis, with an average survival after diagnosis of less than 18 months. Hundreds of clinical trials have been conducted, with more underway to make progress in treating glioblastoma. This review details conventional and emergent targeted therapies for glioblastoma.

Abstract

Glioblastoma is most commonly a primary brain tumor and the utmost malignant one, with a survival rate of approximately 12–18 months. Glioblastoma is highly heterogeneous, demonstrating that different types of cells from the same tumor can manifest distinct gene expression patterns and biological behaviors. Conventional therapies …

We Sing!, April 12, 2024 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Uni Jazz Band One, April 12, 2024 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

2024 Academy Of Law Alumni Fellows Induction Ceremony Program, Maurer School Of Law - Indiana University

Academy of Law Alumni Fellows

The Academy of Law Alumni Fellows was established in 1985 to recognize alumni whose careers are defined by exceptional personal achievement and dedication to the highest standards of the profession.

Academy Fellows are part of an elite group that includes US senators, federal judges, successful business leaders, and distinguished practitioners. A committee of anonymous alumni selects each year’s Fellows from among many deserving candidates. To be named an Academy of Law Alumni Fellow is to receive the very highest honor that the Maurer School of Law can bestow.

This year, we are honored to recognize four alumni whose remarkable contributions …

April 12, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

2023-2024 Master Of Music Recital - Amelia Dixon (Violin), Amelia Dixon, Sheng Yuan Kuan

Master of Music Recitals

No abstract provided.

Immersive Japanese Language Learning Web Application Using Spaced Repetition, Active Recall, And An Artificial Intelligent Conversational Chat Agent Both In Voice And In Text, Marc Butler

MS in Computer Science Project Reports

In the last two decades various human language learning applications, spaced repetition software, online dictionaries, and artificial intelligent chat agents have been developed. However, there is no solution to cohesively combine these technologies into a comprehensive language learning application including skills such as speaking, typing, listening, and reading. Our contribution is to provide an immersive language learning web application to the end user which combines spaced repetition, a study technique used to review information at systematic intervals, and active recall, the process of purposely retrieving information from memory during a review session, with an artificial intelligent conversational chat agent both …

Immune Checkpoint Inhibitors: A Narrative Review On Pd-1/Pd-L1 Blockade Mechanism, Efficacy, And Safety Profile In Treating Malignancy, Ian Brandon

All Publications

Checkpoint inhibitors have been implicated in the treatment of several cancers due to their ability to exploit the immune system's regulatory pathways. This article serves to emphasize the importance of these immunotherapeutic agents and provide further insight into their mechanisms, efficacies, and safety profiles. The main agents in question include programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1). Several literature sources were found to assess the use of these inhibitors in cancers involving the lung, breast, and skin. Several peer-reviewed systematic reviews and the outcomes of clinical trials are combined within this article to support the …

Growth And Yield Response Of Watani Wado Job's Tears (Coix Lacryma-Jobi L.) To The Application Frequency Of Phosphate Fertilizer And Paclobutrazol In Different Growing Seasons, Arifa Syahanna Mahdya, Rizka Farahdillah, Muhamad Kadapi, Tati Nurmala

Jurnal Kultivasi

Job's tears (Coix lacryma-jobi L.) is a carbohydrate source functional food crop that can be developed as a substitute for rice. This study aims to determine the best application frequency of phosphate (P) fertilizer and paclobutrazol for supporting the growth and yield of job's tears in both rainy and dry seasons. The research was conducted from November 2021 - November 2022 at the Ciparanje research station and Laboratory Centre Universitas Padjadjaran, Jatinangor, Sumedang. The experiment used a randomized block design (RBD) consisting of P fertilizer application frequency (once, twice, and thrice) and paclobutrazol application frequency (once, twice, and thrice) and …

2024-04-12 Minutes Of The Academic Senate, University Of Dayton. Academic Senate

Academic Senate Minutes

Approved minutes of a meeting of the Academic Senate of the University of Dayton.

Not All Anemias In Training Room Need Iron Replacement, Spencer Cooper, Jason Meredith

Posters and Presentations: Family Medicine

No abstract provided.

Secondary School Activity Modifications Based On Pre-Event Wbgt Readings, Jason Meredith, Adam B. Rosen, Colleen Vogel, Ross Mathiasen

Posters and Presentations: Family Medicine

No abstract provided.

Data Profits Vs. Privacy Rights: Ethical Concerns In Data Commerce, Amiah Armstrong

Cybersecurity Undergraduate Research Showcase

In today’s digital age, the collection and sale of customer data for advertising is gaining a growing number of ethical concerns. The act of amassing extensive datasets encompassing customer preferences, behaviors, and personal information raises questions of its true purpose. It is widely acknowledged that companies track and store their customer’s digital activities under the pretext of benefiting the customer, but at what cost? Are users aware of how much of their data is being collected? Do they understand the trade-off between personalized services and the potential invasion of their privacy? This paper aims to show the advantages and disadvantages …

Hormetic Modulation Of On Mtor Mitochondria Cross Talk For Mitigation Of Cellular Aging, Mahalakshmi R

Theses and Dissertations

Cellular aging is a gradual process involving structural and functional deterioration of cells. Mitochondria, the biological clock in cells, are known to play a crucial role in the progression of cell aging. According to the mitochondrial free radical theory of aging, oxidative phosphorylation in the mitochondria produces free radicals, such as, reactive oxygen species (ROS), which lead to oxidative stress in cells. This, in turn, results in mitochondrial dysregulation, and eventually causes degeneration of cellular components, thereby propagating cell aging. However, it is to be underscored that aging, at its core, is a multifaceted phenomenon that involves a number of …