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A Rare Case Of Anti-Mda5 Associated Progressive Interstitial Lung Diseases Without Classical Features Of Dermatomyositis., Nimesh Khanal Md, Ayushma Acharya Md, Bharosha Bhattarai Mbbs, Devi Parvathy Jyothi Ramachandran Nair Md, Peter Daniel Nicholas Iii Do Apr 2024

A Rare Case Of Anti-Mda5 Associated Progressive Interstitial Lung Diseases Without Classical Features Of Dermatomyositis., Nimesh Khanal Md, Ayushma Acharya Md, Bharosha Bhattarai Mbbs, Devi Parvathy Jyothi Ramachandran Nair Md, Peter Daniel Nicholas Iii Do

Tower Health Research Day

No abstract provided.


Multi-Omics, Big Data, And How Machine Learning Is Revealing New Biological Insights In Pediatric Brain Cancers, Shehbeel Arif Apr 2024

Multi-Omics, Big Data, And How Machine Learning Is Revealing New Biological Insights In Pediatric Brain Cancers, Shehbeel Arif

Tower Health Research Day

No abstract provided.


Probabilistic Workflow Modeling Of Transfused Injured Children And Adolescents At A Level 1 Trauma Center, Megan Krentsa, Travis M. Sullivan, Keyi Li, Elizabeth Matison, Waverly Gestrich-Thompson, Genevieve J. Sippel, Randall S. Burd, Aleksandra Sarcevic Apr 2024

Probabilistic Workflow Modeling Of Transfused Injured Children And Adolescents At A Level 1 Trauma Center, Megan Krentsa, Travis M. Sullivan, Keyi Li, Elizabeth Matison, Waverly Gestrich-Thompson, Genevieve J. Sippel, Randall S. Burd, Aleksandra Sarcevic

Tower Health Research Day

No abstract provided.


Investigating The Effect Of Orexin 1 Receptor Knockdown In The Paraventricular Nucleus Of The Thalamus On Habituation To Repeated Stress, Jason Yan, Seema Bhatnagar Apr 2024

Investigating The Effect Of Orexin 1 Receptor Knockdown In The Paraventricular Nucleus Of The Thalamus On Habituation To Repeated Stress, Jason Yan, Seema Bhatnagar

Tower Health Research Day

No abstract provided.


When Potassium Cries Wolf: Pseudohyperkalemia In A Hospitalized Patient With Chronic Lymphocytic Leukemia, Leyla Wade, Matthew Kent, Karen Avgush Apr 2024

When Potassium Cries Wolf: Pseudohyperkalemia In A Hospitalized Patient With Chronic Lymphocytic Leukemia, Leyla Wade, Matthew Kent, Karen Avgush

Tower Health Research Day

No abstract provided.


Application Of T Gates For Anti-Concentration In Clifford Circuits, Matthew Dominicis, Mason Toombs, Gabriel Riddle, Parineeta Puja Saha, Himanth Bobba Apr 2024

Application Of T Gates For Anti-Concentration In Clifford Circuits, Matthew Dominicis, Mason Toombs, Gabriel Riddle, Parineeta Puja Saha, Himanth Bobba

Undergraduate Research Conference at Missouri S&T

Our study examines the integration of non-Clifford T gates into randomly generated Clifford circuits to enhance their universal unitary capacity. We investigate the impact of T gates on circuit output randomness, focusing on generating random Clifford circuits and analyzing the effects of T gates. Through simulations and analysis, we assess the effectiveness of this modification in achieving outputs consistent with Anti concentration properties while minimizing the required number of Clifford gates. Our findings provide valuable insights into quantum circuits, with implications for quantum computing applications.


Competition Or Prey: C. Elegans Populations In The Presence Of P. Pacificus, Charles Greene, Elena Zobel, Andrea Scharf Apr 2024

Competition Or Prey: C. Elegans Populations In The Presence Of P. Pacificus, Charles Greene, Elena Zobel, Andrea Scharf

Undergraduate Research Conference at Missouri S&T

The predatory and territorial behaviors of the model organism P. pacificus provides a useful opportunity to study territorial defensive behaviors and optional predatory behaviors in relation to availability of preferred food sources. P. pacificus will be grown with C. elegans in shared cultures, in which E. coli will be placed and used to feed both species of worm. The number of predation events and territory defense events by P. pacificus against C. elegans will be recorded and tracked at differing levels of food concentrations. One potential issue is the different mouth morphs found in P. pacificus, with the stenostomatous (in …


The Application Of Poly-Ε-Caprolactone Nanoparticles For Endotoxin Removal, Mikaela Ritchie Apr 2024

The Application Of Poly-Ε-Caprolactone Nanoparticles For Endotoxin Removal, Mikaela Ritchie

Undergraduate Research Conference at Missouri S&T

Lipopolysaccharides (LPS), also known as endotoxins, are toxins released from the cell walls of gram-negative bacteria upon their death. Ingestion of LPS by humans or animals can initiate inflammatory immune responses, resulting in blood vessels dilation, organ dysfunction and potential death. These toxins contaminate a variety of manufacturing processes from the pharmaceutical industry to animal feed production, posing a risk to humans and animals alike. This study details the production of PCL nanoparticle capable of removing LPS from water and a preliminary analysis of the removal efficiency. The outcomes of this research hold significant implications for industries reliant on bacterial …


Using Efficient Global Optimization With Cfd For Aerodynamic Optimization, Aaron Spillars, Nathan Roberts, Xiaoping Du Apr 2024

Using Efficient Global Optimization With Cfd For Aerodynamic Optimization, Aaron Spillars, Nathan Roberts, Xiaoping Du

Undergraduate Research Conference at Missouri S&T

Machine learning and optimization are the stepping blocks in broad engineering areas, such as computational fluid dynamics (CFO) and CFO-based design optimization. Using the CFO-based optimization framework, MACH-Aero, we were able to use the SLSQP optimizer and compared the results with a reference case completed by the SNOPT optimizer. Results verified that our SLSQP optimizer was working properly. The solver created showed that our objective function had a difference in magnitude of 0.000019 allowing us to conclude that our solver was working as intended. However, there were several failed attempts before reaching a successful run that gave us a satisfactory …


The History Of The Billboard Hot 100 And Its Process, Brileigh Cates Apr 2024

The History Of The Billboard Hot 100 And Its Process, Brileigh Cates

Undergraduate Research Conference at Missouri S&T

The Billboard Hot 100 has been around for decades, and it is believed without much accreditation. What really is Billboard, and why is it so popular? Why have other charting companies not taken up as much popularity? How does Billboard determine the popularity of artists? How has this changed with the introduction of the internet? This research project addresses all of these question, allowing the validity of the data collection to be addressed.


Lung Cancer Drug Study Using Alc Nanoparticles, Noah Sparks Apr 2024

Lung Cancer Drug Study Using Alc Nanoparticles, Noah Sparks

Undergraduate Research Conference at Missouri S&T

In a previous project it was determined ALC polarized lipid nanoparticles have a high transfection efficiency in some lung cancer cell lines. Building off this information, these ALC particles will now be tested with an actual lung cancer drug. This process will consist of searching articles for promising lung cancer drugs and selecting one for use. The ALC particles will then undergo a comprehensive drug study using multiple lung cancer cell lines with the selected drug. Aspects such as drug release rate, transfection rate, cytotoxicity, etc. will be determined. The goal is to determine whether ALC nanoparticles show real promise …


Numerical Studies On Bose–Einstein Condensates, Megan Benkendorf Apr 2024

Numerical Studies On Bose–Einstein Condensates, Megan Benkendorf

Undergraduate Research Conference at Missouri S&T

Bose-Einstein condensate (BEC) is a state of matter near absolute zero temperature for which all atoms lose their individual properties and condense into a macroscopic coherent "super-wave". The superfluidity of BEC has been the focus of active research since the first experimental realization of BEC in 1995. The recent launch of the Cold Atom Laboratory to the space station on May 21, 2018, has once again drawn spotlights to these fascinating properties of BEC. In this project, we will carry out numerical studies to understand the behavior of exciton-polariton BECs. A modified Gross-Pitaevskii equation is used to model the dynamics …


American Resistance: The Bund And Their Opposition, Emily Copeland Apr 2024

American Resistance: The Bund And Their Opposition, Emily Copeland

Undergraduate Research Conference at Missouri S&T

This Honors Thesis investigates American opposition to the German American Bund during the turbulent 1930s. It reveals the differing attitudes within American society during the German American Bund's peak. While some embraced fascist ideologies, others protested against them, highlighting the intricacy of American politics leading up to World War II. This study explores the efforts undertaken by Americans to counter the fascist doctrine of the German American Bund on democratic soil. The research gathered insight from documents and artifacts at institutions such as the St. Louis Kaplan Feldman Holocaust Museum, Curtis Laws Wilson Library, and other archival sources, investigating the …


Neurodiversity And Openness In Responses To Al In Writing, Joely Grace Hall Apr 2024

Neurodiversity And Openness In Responses To Al In Writing, Joely Grace Hall

Undergraduate Research Conference at Missouri S&T

Neurodivergent individuals encompass a broad spectrum of cognitive profiles, including autism, ADHD, dyslexia, depression, anxiety and other neurological differences and learning disabilities. Over the past decade, artificial intelligence (Al) technologies have rapidly evolved, permeating various aspects of society, from healthcare to education and employment. Al often makes mistakes when analyzing papers written by neurodivergent students and flags them for plagiarism, when there is no plagiarism in the paper. We want to investigate why this happens and ways to work around this. We have put together a Prolific survey to get general opinions on Al, neurodiversity types and writing classes. With …


Uncertainty Quantification Of Thermal Capacitance Calorimeter For High-Enthalpy Flows, Logan Banker, Davide Vigano Apr 2024

Uncertainty Quantification Of Thermal Capacitance Calorimeter For High-Enthalpy Flows, Logan Banker, Davide Vigano

Undergraduate Research Conference at Missouri S&T

Thermal capacitance calorimeters are the standard instrument used to measure cold wall heat fluxes in high-enthalpy flows that simulates hypersonic flight conditions. These instruments play a fundamental role in the development and testing of Thermal Protection Systems for space re-entry conditions. However, despite their rugged and simple design, they are affected by large uncertainty errors. These have been estimated in literature at 15%. Despite their importance, and large errors, no proper uncertainty analysis has been performed. Uncertainty analysis is difficult due to the complex physics of the environment these calorimeters have to operate into.


Analysis Of The Benefits And Risks Of Just In Time Inventory Management, Ian Hodge Apr 2024

Analysis Of The Benefits And Risks Of Just In Time Inventory Management, Ian Hodge

Undergraduate Research Conference at Missouri S&T

Just in time (JIT) inventory management has become increasingly popular in industry due to its well known benefits. JIT aims to streamline inventory processes by minimizing excess stock, reducing holding costs, and improving operational efficiency overall. This approach introduces inherent risks, by minimizing the safety stock the company becomes more vulnerable to supply chain disruptions. If unexpected circumstances lead to a supply delay, the company will rapidly deplete their supplies and may have to cease operations until they are resupplied, resulting in decreased revenue and leaving customers unfulfilled.This research project will examine case studies of companies that adopted JIT methodology …


Thermo-Gravimetric Analysis Of Variables Of Oxidization, Clark Nguyen, Mario F. Buchely Apr 2024

Thermo-Gravimetric Analysis Of Variables Of Oxidization, Clark Nguyen, Mario F. Buchely

Undergraduate Research Conference at Missouri S&T

Oxidation phenomena play a critical role in high temperature metallurgical processing and the performance during life cycle of components made of both high and low alloy steels. Therefore, the development of a precise experimental methodology to quantify oxidation processes is critically important. This report summarizes my experimental study of the oxidation behavior of high and low alloy steel, including kinetics of surface oxide layer formation and spallation. The focus of study was in determining the complex interactions between alloying elements in steel matrix and oxidation environment, composition and surface morphology of formed oxides. This report will also explore how the …


Development Of A Force Perturbation Handle For Physical Interaction Research In Humans, Henry Tien, Riley Still, Yun Seong Song Apr 2024

Development Of A Force Perturbation Handle For Physical Interaction Research In Humans, Henry Tien, Riley Still, Yun Seong Song

Undergraduate Research Conference at Missouri S&T

The vision of developing more advanced robots that physically interact with people begins with the study of how people interact with each other. Even the simplest interactions between humans, such as shaking hands, provides tremendous challenges for current robots and minimal research has been conducted on the inner workings of these interactions. Understanding the process and mechanics behind effective and intuitive physical human-human interaction (pHHI) will yield meaningful insight into designing robots capable of assisting the elderly, operating side by side with workers, or even dancing with people. To study this process, a custom Force Perturbation Handle (FPH) was developed, …


A New Genetic Tool For Quorum-Sensing Ba, Amelia Markwell Apr 2024

A New Genetic Tool For Quorum-Sensing Ba, Amelia Markwell

Undergraduate Research Conference at Missouri S&T

This current research project focuses on the use of cell-to-cell communication in Bacterial Strain competition, specifically in soybean plants. Soybean plants are a high-yield crop produced here in the midwest, bringing in more than 8 billion dollars in monetary output for our state. The lab work focuses on one specific bacteria strain farmers commonly find in soybeans; this is called Bradyrhizobium japonicum. This nitrogen-fixing bacteria improves plant growth drastically. Cells have a way of communicating with each other in order to share information and adjust gene regulation accordingly. This is known as quorum sensing. My research last year focused on …


Modality's Effect On Aesthetic Ratings Of Poetry, Jessica Frame Apr 2024

Modality's Effect On Aesthetic Ratings Of Poetry, Jessica Frame

Undergraduate Research Conference at Missouri S&T

Previous research has shown that vividness of evoked imagery is the strongest contributor to aesthetic pleasure for poetry. However, it is 114 unknown whether modality of the poem has an effect on the relationship between vividness and aesthetic appeal, as past work has only used written poems. In this study we want to evaluate rating of vividness, valence, arousal, and aesthetic appeal based on the modality in which poems are presented (listening only, reading only, or combined). Participants were randomly assigned to one of the three modalities: text-only (N=81 ), audio-only (N=74), or combined audio/text (N=78). Our results showed that …


Biosensors For Antibacterial Medical Applications, Ryan Fagan, Shelby Wallen Apr 2024

Biosensors For Antibacterial Medical Applications, Ryan Fagan, Shelby Wallen

Undergraduate Research Conference at Missouri S&T

Healthcare associated infections are significant concern in medicine and as antibiotics are becoming less effective, we need new alternative methods to treat them. We are testing various materials that can be used to prevent infections in healthcare settings and in wound treatments. These materials include bioactive glass and modified hydrogel materials. From these studies we've learned these are effective in killing bacteria and preventing infections. The goal of this project is to determine the mechanism at which these materials kill bacteria. Our approach is to construct biosensor strains that can indicate bacterial stress response to antimicrobial agents. We have used …


A Fisher Information-Based Approach To Improve Labeling Efficiency Of Neural Network Models In Image Classification, Joshua Caruso Apr 2024

A Fisher Information-Based Approach To Improve Labeling Efficiency Of Neural Network Models In Image Classification, Joshua Caruso

Undergraduate Research Conference at Missouri S&T

Active learning is a framework for training machine learning models where the goal is to reduce the number of labels used during training. Neural network models used for image classification require a large training dataset to achieve good accuracy. This project will use active learning to reduce the number of labels needed for training neural network models. We propose to use the Fisher information of the neural network parameters to actively select which images are labelled and included in the training data. A key challenge is the large number of parameters in commonly used neural network models, which significantly increases …


How Does The C-Terminus Of Iqg1 Work In Cytokinesis?, Rae Tordilla, Katie Shannon Apr 2024

How Does The C-Terminus Of Iqg1 Work In Cytokinesis?, Rae Tordilla, Katie Shannon

Undergraduate Research Conference at Missouri S&T

During cytokinesis, the division of the cytoplasm between cells is controlled by the contraction of an actomyosin ring. Iqg1, a crucial regulator of cytokinesis in Saccharomyces cerevisiae, is needed for the assembly and contraction of this ring. Already, it has been found that a domain in the Iqg1 C-terminus is crucial for S. cerevisiae survival. In this study, a regulated Iqg1 allele is introduced to yeast. This will allow researchers to turn off the wild-type allele of the Iqg1 gene under specified conditions, which allows for the study of the effects of the C-terminal Iqg1 deletion. Progress towards making the …


Molecular Genetics And Phylogeny Of Bigmouth Shiner, Notropis Dorsalis, James Ramette, Patrick Appiah, Shila Koju, Jacqueline Kluba, Heath St, Dennis, Christian Bigler, Robert Hrabik, David D. Duvernell Apr 2024

Molecular Genetics And Phylogeny Of Bigmouth Shiner, Notropis Dorsalis, James Ramette, Patrick Appiah, Shila Koju, Jacqueline Kluba, Heath St, Dennis, Christian Bigler, Robert Hrabik, David D. Duvernell

Undergraduate Research Conference at Missouri S&T

The study of North American freshwater ichthyofauna reveals a diversity shaped by the continent's geologic past and the extensive effects of Pleistocene glaciation on river systems. Ericymba dorsalis (Bigmouth 69 Shiner) is a minnow species with a broad distribution in the Mississippi River basin from Wyoming to New York. Despite exhibiting consistent morphological features across its range, the species' widespread northern distribution suggests the potential existence of multiple, genetically distinct lineages. This research tested the hypothesis that separate drainage systems harbor genetically distinct groups of E. dorsalis. Our results identified five clades, each associated with major drainages. Populations of the …


Co2 Pricing Pass-Through To Electricity Prices Under Partial Regulations, Love Gami Apr 2024

Co2 Pricing Pass-Through To Electricity Prices Under Partial Regulations, Love Gami

Undergraduate Research Conference at Missouri S&T

With climate change becoming a growing concern, carbon trading has gained attention as a key solution to reducing carbon emissions. However, this raises a concern about whether polluters pass the cost of carbon to electricity prices. This study aims to assess the impact of CO2 pricing on electricity prices in the PJM market where some areas are regulated by carbon trading while others are not. Our findings reveal a significant impact of CO2 prices across all regulated areas, encompassing both real- time and day-ahead markets. Moreover, the impact extends to non-regulated areas, indicating a spillover effect within the PJM market. …


Test-Optional Policy’S Impact On Statewide Act Scores, D. Steven Stutts Apr 2024

Test-Optional Policy’S Impact On Statewide Act Scores, D. Steven Stutts

Undergraduate Research Conference at Missouri S&T

This study investigates the causal impact of test-optional policies on statewide average ACT scores. A panel dataset comprised of participation rates and average composite ACT scores over an eight-year period for nine states that began the period with 100 percent participation was collected using annual reports released by the ACT corporation and available on the National Center for Education Statistics (NCES) website. A generalized difference-in-differences design with staggered treatment periods was implemented, with states using a test-mandatory regime spanning the eight-year period constituting the control group and states that began the period as test-mandatory and switched to test-optional at some …


Microbial Matrix: Genetic And Chemical Aspects Of Cell-Cell Communication, Amelia Markwell, Sophia Nicolette Militante Apr 2024

Microbial Matrix: Genetic And Chemical Aspects Of Cell-Cell Communication, Amelia Markwell, Sophia Nicolette Militante

Undergraduate Research Conference at Missouri S&T

This research project focuses on looking at different quorum-sensing positive strains in bradyrhizobium japonicum, a species of legume-root bacteria found in soybean plants across the Midwest. Soybean plants are a high-yield crop produced here in the midwest, bringing in more than 8 billion dollars in monetary output for our state, making it Missouri's economic engine. Our objective, is to use different chemical testing methods to distinguish genetic differences between negative strains. This can be done through polymerase chain reaction, gel electrophoresis, and gene editing. Our goal has been to PCR amplify a fine-tuned promoter then clone it into the gene. …


The Influence Of Sensory Modality On Aesthetic Judgments Of Poetry, Jessica Frame, Kendra Mehl Apr 2024

The Influence Of Sensory Modality On Aesthetic Judgments Of Poetry, Jessica Frame, Kendra Mehl

Undergraduate Research Conference at Missouri S&T

Previous research has shown that vividness of evoked imagery is the strongest contributor to aesthetic pleasure for poetry. However, it is 19 unknown whether modality of the poem has an effect on the relationship between vividness and aesthetic appeal, as past work has only used written poems. In this study we want to evaluate rating of vividness, valence, arousal, and aesthetic appeal based on the modality in which poems are presented (listening only, reading only, or combined). Participants were randomly assigned to one of the three modalities: text-only (N=81 ), audio-only (N=74), or combined audio/text (N=78). Our results showed that …


Comparing Autobiographical Memories Evoked By Different Sensory Cues For Younger And Older Adults, Akira Durbin Apr 2024

Comparing Autobiographical Memories Evoked By Different Sensory Cues For Younger And Older Adults, Akira Durbin

Undergraduate Research Conference at Missouri S&T

Music has the power to take us back in time. Previous research indicates that music is a potent autobiographical memory cue, and that recall often happens with no effort on the part of the listener. Our research is also informed by the reminiscence bump phenomenon, which describes the tendency of older adults to recall autobiographical memories formed from the ages of 18-35. Informed by this phenomenon, we presented older participants with stimuli that were relevant during their youth. We displayed different stimuli to younger and older adult participants on a desktop computer. The stimuli we presented were popular music clips, …


The Search For The Akwamu People In The Americas, 1729-1733, Ben Brown, Justin Pope Apr 2024

The Search For The Akwamu People In The Americas, 1729-1733, Ben Brown, Justin Pope

Undergraduate Research Conference at Missouri S&T

This Poster presentation attempts to trace the journey of one nation of Africans into the Americas. In 1729, the Akwamu Empire, in modern day Ghana, West Africa, suffered a terrible collapse. Rival African armies enslaved thousands of Akwamu subjects and sold them to European slavers on the Gold Coast. This nation later led the biggest island wide slave revolt prior to the age of revolution in the Americas. Using primary and secondary resources such as the "Transatlantic Slave Trade Database," we will attempt to identify the European slave ships that purchased enslaved Akwamu people and trace their journey into the …