Digital Commons Network^™

Multi-Faceted Approach To Educating Physicians About The Impacts Of Climate Change On Their Patients’ Health, Deborah Simpson, Anne Getzin, Kjersti Knox, Kari A. Schmidt Oliver, Victoria Gillet, Karen Hanus, Amina Maamouri, Nicole Heilman, Rita Mitchell, Yolanda Manson, Kristin Ouweneel, Kathryn Agard

Aurora GME

No abstract provided.

Population Health Pop-Spotting, Stephenie Quirke, Morgan Erickson, Catherine Degrandville, Glenda Sundberg, Christina Dukehart, Will Lehmann

Aurora GME

No abstract provided.

Stop-Ama: A Quality Improvement Project To Reduce Ama Discharges Through Early Recognition And Intervention, Sean Fabry, David Hamel

Aurora GME

No abstract provided.

Vot+Er: Voter Registration To Address Structural & Social Determinants Of Health, Terry Frederick, Tricia La Fratta, Deborah Simpson, Victoria Gillet, Lawrence Moore, Kjersti Knox, Esmeralda Santana, Oyinkansola Okubanjo, Nicole Salvo, Jacob Bidwell, Kristin Ouweneel

Aurora GME

No abstract provided.

A Macrophage-Cell Model Of Hiv Latency Reveals The Unusual Importance Of The Bromodomain Axis, Javan K Kisaka, Daniel Rauch, Malachi Griffith, George B Kyei

2020-Current year OA Pubs

BACKGROUND: Although macrophages are now recognized as an essential part of the HIV latent reservoir, whether and how viral latency is established and reactivated in these cell types is poorly understood. To understand the fundamental mechanisms of viral latency in macrophages, there is an urgent need to develop latency models amenable to genetic manipulations and screening for appropriate latency-reversing agents (LRAs). Given that differentiated THP-1 cells resemble monocyte-derived macrophages in HIV replication mechanisms, we set out to establish a macrophage cell model for HIV latency using THP-1 cells.

METHODS: We created single-cell clones of THP-1 cells infected with a single …

Mamás Metidas: Empowering Latinx Spanish-Dominant Parents In Independent Schools Through Culturally Responsive School Leadership, Silvia Salazar Rivera

LMU Theses and Dissertations

Latinx families, particularly those whose primary language is Spanish, are significantly underrepresented in independent schools nationwide and experience barriers to engaging in their children’s education. Recognizing the crucial role of parent engagement in student academic success and socioemotional well-being, this research aimed to understand the unique challenges faced by Spanish-dominant parents in navigating the independent school contexts. Grounded in Khalifa et al.’s (2016) culturally responsive school leadership framework, the study intended to identify effective practices and strategies that facilitate Spanish-dominant parent engagement. The narrative data, collected through both a group plática and individual interviews, offered valuable insights into the experiences …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

The Relationship Between Immune-Related Adverse Events During Ipilimumab Monotherapy And Survival Outcomes Among Melanoma Patients: A Systematic Review, Jason Sheng, Manav Nayeni, Monali Malvankar

Student Publications

Background: Ipilimumab disinhibits immune system activity which results in the elimination of malignant cells. An unintended consequence of ipilimumab therapy is off-target immune-related adverse events (irAEs). It has therefore been proposed that the incidence of irAEs is a manifestation of treatment effectiveness. The objective of this systematic review is to examine the relationship between irAEs and survivability among melanoma patients administered ipilimumab monotherapy.

Methods: A comprehensive search was conducted across several databases which yielded a total of 2381 studies. Clinical trials and prospective studies administering ipilimumab monotherapy to melanoma patients were included. Furthermore, there was no restriction placed on publication …

Application Of Deep Learning On Mammographies To Discriminate Between Low And High-Risk Dcis For Patient Participation In Active Surveillance Trials, Sena Alaeikhanehshir, Madelon M Voets, Frederieke H Van Duijnhoven, Esther H Lips, Emma J Groen, Marja C J Van Oirsouw, Shelley E Hwang, Joseph Y Lo, Jelle Wesseling, Ritse M Mann, Jonas Teuwen

Faculty, Staff and Student Publications

BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to invasive breast cancer, but most DCIS lesions never will. Therefore, four clinical trials (COMET, LORIS, LORETTA, AND LORD) test whether active surveillance for women with low-risk Ductal carcinoma In Situ is safe (E. S. Hwang et al., BMJ Open, 9: e026797, 2019, A. Francis et al., Eur J Cancer. 51: 2296-2303, 2015, Chizuko Kanbayashi et al. The international collaboration of active surveillance trials for low-risk DCIS (LORIS, LORD, COMET, LORETTA), L. E. Elshof et al., Eur J Cancer, 51, 1497-510, 2015). Low-risk is defined as grade I or II DCIS. Because …

Impact Of Living Donor Liver Transplantation On The Improvement Of Hepatocellular Carcinoma Treatment, Yucel Yankol, Oswaldo Aguirre, Luis A Fernandez

Faculty, Staff and Student Publications

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths, with increasing incidence. There are different treatment options, but only 30%-40% of HCC cases are diagnosed at an early stage for curative treatment. With the implementation of Milan Criteria for liver transplantation (LT) in HCC cases and its use for organ allocation with successful outcomes, LT has become an optimal treatment. Seeking new criteria for LT and developing updated algorithms for HCC treatment has become a hot topic nowadays. With the experience in living donor liver transplantation (LDLT), especially in Asian countries, LDLT was established and adopted with …

The Saga Of E Faecium, Rishika Prasad, Robert R Jenq

Faculty, Staff and Student Publications

An enzyme that remodels the cell wall of Enterococcus faecium helps these gut bacteria to divide and generate peptide fragments that enhance the immune response against cancer.

Race And Racism Through The Lens Of Black Men: Exploring The Talk And Lessons Black Fathers Teach Their Children About Race And Racism In America., Conial C. Caldwell Jr

LSU Doctoral Dissertations

The history of racism and racial violence is embedded in the fabric of America and has driven Black people to develop strategies to navigate society that racism has produced. “The Talk” is a racial socialization practice and cultural phenomenon that has existed within Black families for centuries and remains a necessity due to the ongoing acts of racism and violence of Black Americans. Prior research has found that parents rear their children based on their own lived experiences, which many Black Americans have experienced or have been exposed to racism and racial violence. Yet, there are few empirical studies that …

A Study Of Selected Vocal Works By Shande Ding: The Mysterious Sound Of Flute And Poems On Western Yunnan, Chuyan Luo

LSU Doctoral Dissertations

This study aims to delve into and interpret “The Mysterious Sound of Flute” and “Poems on Western Yunnan” from a singer’s perspective while also providing guidance and recommendations for other performers. The research encompasses the history of Chinese art songs, a biography of Shande Ding, and an introduction to his compositional style. A comprehensive examination of each song includes background information, song analysis, translation, a Chinese lyric diction guide, and performance suggestions.

Art songs constitute a significant genre in music composition, and Chinese art songs have yielded numerous outstanding composers and captivating works over the years. Among these composers, Shande …

Spatial Behavior Of Hospital Visits By Hand, Foot, And Mouth Disease Patients In Nanchang, China, Zeliu Zheng

LSU Doctoral Dissertations

Hand foot mouth disease (HFMD) is one of the widespread transmissible diseases that target preschool children, especially in urban regions in East Asia. Understanding the travel patterns of the HFMD patients helps us understand how the spatial behaviors of patients vary across space and what are the underlying forces. It is essential for understanding the healthcare market and planning for resource allocation. Foremost, health behavior and outcome change significantly across geographic regions of various urbanicities (i.e., degrees of urbanization) due to the uneven distribution of healthcare resource. In addition, health studies in the U.S. often use hospital service areas (HSAs) …

Flaxman, Judy, Laura Oldfather

Bronx Jewish History Project

Summarizer: Sophia Maier

Judy Flaxman’s family came to the Lower East Side from Eastern Europe in the early 1900s. As they grew more affluent, they moved to the Bronx, where Flaxman was born in 1948. She lived on Walton Avenue near Tremont Avenue, which she describes as very Jewish with some Catholics. She attended PS 28, Wade Junior High School, and Bronx Science. She played many outdoor games with friends from her community and did after school activities at the YM/WHA, through which she attended a day camp during the summers.

Flaxman’s mother was a secretary and her father, after …

Investigating The Role Of Fluid Shear Stress During Metastasis On Enhanced Breast Cancer Extravasation, Alejandra M. Ham

LSU Master's Theses

In 2022, ~288,000 American women were diagnosed with metastatic breast cancer which was the leading cause of patient mortality with ~43,000 American women succumbing to the disease. Women can be diagnosed with four different molecular subtypes of breast cancer: luminal A, luminal B, human epithelial growth receptor type 2 enriched (HER2+), and triple-negative breast cancer (TNBC). TNBC accounts for ~12% of all breast cancers, yet it has the worst outcomes. TNBC is highly invasive, with ~46% of TNBC patients developing metastatic disease. A further understanding of metastatic TNBC is needed to provide a greater understanding of how to treat this …

Design And Test Of Wpum Topography Monitor For Iqos, Rawah Azeez

Theses

With the emergence of diverse tobacco product forms, such as electronic cigarettes and heat-not-burn, the global user base has surged to an estimated 1.3 billion. In the United States, 28.3 million adults and 3.08 million middle and high school adolescents engage in tobacco product use. However, our understanding of the usage behaviors of these various products is lacking. Puff topography, which measures the inhalation patterns of tobacco products, provides a wealth of information, including puff flow rate, duration, volume, and more. This information is crucial in understanding the health effects of tobacco products and the influence of usage behavior on …

Supercook: Design Interactive Culinary Experiences With Ai Technology, Yize Peng

Theses

The project 'SuperCook' is a groundbreaking design project that explores the integration of AI with culinary apps. It aims to revolutionize the kitchen experience by connecting users to new and accessible culinary adventures through personalized recipe recommendations, real-time cooking guidance, and interactive meal planning. By leveraging AI technology, 'SuperCook' not only enhances user convenience and efficiency but also fosters a deeper engagement with cooking and promotes healthier eating habits. This thesis delves into the design process, user testing, and iterative improvements that culminated in a user-centered, intuitive, and visually appealing UI/UX solution for modern cooking enthusiasts. In designing 'SuperCook,' attention …

Senior Recital: Peyton Gray, Trombone; Lu Witzig, Piano; April 5, 2024, Peyton Gray, Lu Witzig

School of Music Programs

Kemp Recital Hall
April 5, 2024
Friday Evening
9:00 p.m.

Junior Recital: Jennifer Budlong-Brewer, Saxophone; Lu Witzig, Piano; Lauren Cancio, Trumpet; April 5, 2024, Jennifer Budlong-Brewer, Lu Witzig, Lauren Cancio

School of Music Programs

Kemp Recital Hall
April 5, 2024
Friday Evening
6:00 p.m.

Swiss Cheese Heart: A Tale Of Multiple Valve Perforations, Hussam Al Hennawi, Shayan I. Khan, Aamna Khan, Usama Sadiq, Sung-Hae Cho

Abington Jefferson Health Papers

Gerbode defect, an anomalous connection between the left ventricle and right atrium, is often congenital but can be acquired or iatrogenically formed. We present an exceedingly rare case of this defect associated with multiple valve perforation in an otherwise healthy patient with bicuspid aortic valve and endocarditis.

We Don't Talk About Insurance (No, No, No!), Anthony J. Sebok

Articles

Kenneth S. Abraham and Catherine M. Sharkey's The Glaring Gap in Tort Theory has a dramatic title. The article, which is about the unheralded and unappreciated role that liability insurance plays in tort, promises to make good on two claims-first, that the major (or a major) "missing piece" in modern tort scholarship is liability insurance, and second, once this missing piece is identified, it is impossible to ever see tort law the same way again.

Sophomore Recital: Chelsea Davis, Flute; Lu Witzig, Piano; April 5, 2024, Chelsea Davis, Lu Witzig

School of Music Programs

Kemp Recital Hall
April 5, 2024
Friday Evening
7:30 p.m.

Supply, Demand, And Fiscal Sustainability Of Outdoor Recreation In Utah, Jordan W. Smith, Chris Monz

Environment and Society Faculty Publications

Because Utah's outdoor recreation destinations are managed by several different federal and state agencies, there is no comprehensive and consistent information on the amount and types of outdoor recreation resources available within the state. Additionally, there has been no research to date on how state programs whose revenues are dependent on outdoor recreation activity, are likely to fare in the coming years. This report begins to address these limitations by: 1) compiling and synthesizing data that characterize the amount and location of outdoor recreation resources throughout the state; and 2) presenting the results of a suite of econometric forecasting models …

2023-2024 Performance Forum - April 5, 2024, Juan Ignacio Díaz, Anna Dunford, Jeremiah Grace, Steven Halpner, Caroline Drantal, Eliza Willett, Jeremy Jefferson, Anttuan Rios Pelaez, Jasmin Abdunazarova, Esther Platt, Victoria Bramble, Samuel Dionisio, Niloufar Mirzanabi Khani, Adriana Fernandez, Angela Fiedler, Lauren Swartz, Jon Cruz

Performance Forum

No abstract provided.

Subcellular Pathways Through Vglut3-Expressing Mouse Amacrine Cells Provide Locally Tuned Object-Motion-Selective Signals In The Retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam Mccoy, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan

2020-Current year OA Pubs

VGluT3-expressing mouse retinal amacrine cells (VG3s) respond to small-object motion and connect to multiple types of bipolar cells (inputs) and retinal ganglion cells (RGCs, outputs). Because these input and output connections are intermixed on the same dendrites, making sense of VG3 circuitry requires comparing the distribution of synapses across their arbors to the subcellular flow of signals. Here, we combine subcellular calcium imaging and electron microscopic connectomic reconstruction to analyze how VG3s integrate and transmit visual information. VG3s receive inputs from all nearby bipolar cell types but exhibit a strong preference for the fast type 3a bipolar cells. By comparing …

Blocking Senescence And Tolerogenic Function Of Dendritic Cells Induced By Γδ Treg Cells Enhances Tumor-Specific Immunity For Cancer Immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng

2020-Current year OA Pubs

BACKGROUND: Regulatory T (Treg) cells are a key component in maintaining the suppressive tumor microenvironment and immune suppression in different types of cancers. A precise understanding of the molecular mechanisms used by Treg cells for immune suppression is critical for the development of effective strategies for cancer immunotherapy.

METHODS: Senescence development and tolerogenic functions of dendritic cells (DCs) induced by breast cancer tumor-derived γδ Treg cells were fully characterized using real-time PCR, flow cytometry, western blot, and functional assays. Loss-of-function strategies with pharmacological inhibitor and/or neutralizing antibody were used to identify the potential molecule(s) and pathway(s) involved in DC senescence …

Assessing The Spatial Variability Of Soil Physical Properties Under A Corn Field In Kentucky, Usa, Sai Neela Kesumala

Scholars Week

Analyzing soil physical properties is crucial for advancing sustainable and precision agricultural practices in today's world. Sustainable agriculture emphasizes responsible resource utilization and preservation. Precision agriculture utilizes technology, data, and targeted decision-making to optimize resource usage and minimize environmental impacts. Assessing soil property variability aids in efficient input application, irrigation adjustment, nutrient runoff reduction, and fertilizer management. This approach prioritizes soil conservation, boosts sustainability, and supports long-term agricultural productivity. This study aimed to evaluate the spatial distribution of specific soil physical properties across the four border rows, central corn field area, and sod area. Seventy-two soil samples were collected from …

A Review On Elitist Ant System Algorithm And Applications In Flexible Job Scheduling Problem, Zainab A. Abd Alhussain, Luma S. Hassan

Al-Bahir

Scheduling is an important technique being used widely in numerous applications especially in industry .Flexible Job Shop Scheduling Problem (FJSP) is an extension of job scheduling which has several practical applications , (FJSP) is NP-hard combinatorial optimization problem. Owing to its importance and intricacy a lot of attention has been paid to this topic. Many swarm intelligent algorithms have drawn inspiration from nature; one particularly notable example is Ant Colony Optimization (ACO), which has shown to be incredibly successful and productive when applied to high-complexity(NP-hard) combinatorial optimization tasks. The paper presents a literature survey on ACO variants types and applications …

Cognitive And Economic Development, John Luke Gallup

OHSU-PSU School of Public Health Annual Conference

A burgeoning literature finds that early childhood risk factors have large causal effects on individuals' cognitive development, education and earnings, but has not assessed the impact on the economy as a whole.

Cognitive ability is the foundation of human capital and the capacity to learn. The risk factors for poor cognitive development are very high in many countries. Each risk factor also causes child mortality, making child survival a viable proxy for good cognitive development conditions. The cognitive development of current workers happened decades earlier when they were children, providing a predetermined correlate. Controlling for country characteristics, income levels and …