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The Jesuit Tradition Of Astronomy At Holy Cross, Sarah Campbell M.A., M.S.I.S. Apr 2024

The Jesuit Tradition Of Astronomy At Holy Cross, Sarah Campbell M.A., M.S.I.S.

Staff publications

This paper summarizes the study of astronomy and related fields as part of the curriculum at the College of the Holy Cross. It briefly profiles four Jesuit priests who were associated with Holy Cross and made significant contributions to the study of astronomy, solar physics and other scientific disciplines. The history of a campus observatory is briefly described as well.

This paper was presented an event sponsored by the Holy Cross Libraries to commemmorate the solar exclipse which occurred April 8. 2024.


Dean Melanie Leslie’S Office Hours, Benjamin N. Cardozo School Of Law Apr 2024

Dean Melanie Leslie’S Office Hours, Benjamin N. Cardozo School Of Law

2024 Event Invitations

Join Dean Leslie and Professor Emeritus Richard Weisberg, author of ‘Vichy Law and the Holocaust in France,’ for a discussion on World War II, the Nazi occupation of France and how the French legal system was changed to perpetuate the Holocaust in France.


Apprenticeships In The Mountain West, Fy2023, Annie Vong, Caitlin J. Saladino, William E. Brown Jr. Apr 2024

Apprenticeships In The Mountain West, Fy2023, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.

Economic Development & Workforce

This fact sheet examines data on apprenticeships for the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The original dataset from the U.S. Department of Labor includes data on all 50 states as well as U.S. territories. This fact sheet examines the number of apprenticeships, the average and median hourly wages, the education level of those in apprenticeships, the union status, and the industries that support apprenticeships in each Mountain West state.


Toward The Substitutionary Promise Of Ptab Review, Saurabh Vishnubhakat Apr 2024

Toward The Substitutionary Promise Of Ptab Review, Saurabh Vishnubhakat

Online Publications

Although administrative patent trial proceedings under the Leahy-Smith America Invents Act (AIA) have done much to improve the efficient reevaluation of patent validity, significant problems remain. Divergent burdens of proof among the United States Patent and Trademark Office (USPTO) and Patent Trial and Appeal Board (PTAB) and the U.S. district courts allow the agency to disregard prior judicial decisions about patent validity and for patents to be relitigated even after surviving judicial review. Divergent claim construction standards allow for similar arbitrage, and, although the USPTO has now aligned its claim construction approach with that of the courts through rulemaking, that …


Improving Breastfeeding Outcomes: A Pilot Randomized Controlled Trial Of A Self-Efficacy Intervention With Primiparous Mothers, Karen A. Mcqueen Apr 2024

Improving Breastfeeding Outcomes: A Pilot Randomized Controlled Trial Of A Self-Efficacy Intervention With Primiparous Mothers, Karen A. Mcqueen

Dissertations

Breastfeeding is recommended as the optimal source of nutrition for newborns for the first 6 months of life and beyond with the addition of complementary foods. While breastfeeding initiation rates have been increasing, duration rates remain a concern as many women prematurely discontinue due to difficulties encountered rather than maternal choice. In addition, there is a sizable gap between rates of exclusive breastfeeding and current recommendations. Targeting modifiable variables that may be amenable to intervention is one strategy to improve breastfeeding outcomes. One such modifiable variable is breastfeeding self-efficacy. Although research has clearly shown that breastfeeding self-efficacy is predictive of …


[Excerpt From] Self-Care For New And Student Nurses (2nd Ed.), Dorrie K. Fontaine, Tim Cunningham, Natalie B. May Apr 2024

[Excerpt From] Self-Care For New And Student Nurses (2nd Ed.), Dorrie K. Fontaine, Tim Cunningham, Natalie B. May

Sigma Publications: Book Excerpts

This item record pertains to an excerpt from Self-Care for New and Student Nurses, Second Edition, which is provided free of charge by the publisher.

About this book:

As a nursing student, you're taught to expect a variety of challenges while caring for your patients and juggling competing priorities as you begin your career. And, though you may know better, your personal well-being can become the last thing you consider in your hectic student or new-nurse life.

This second edition of Self-Care for New and Student Nurses equips you to confidently face stressors now and in the future. No …


Plaza Borinquen 88 Owner Ii Lp V. Montalvo Apr 2024

Plaza Borinquen 88 Owner Ii Lp V. Montalvo

All Decisions

Landlord sought eviction of a Rent Stabilized, project-based Section 8-subsidized tenant,, citing substantial violation of HUD rules due to the tenant's status as a Level Two sex offender and alleged criminal activity. The tenant contested proper service of the termination notice and notice of petition, highlighting procedural irregularities. The court determined the termination notice's sufficiency and found the tenant sufficiently rebutted service, leading to a denial of the landlord's motion and a win for the tenant.


Mir-574-5p Activates Human Tlr8 To Promote Autoimmune Signaling And Lupus, Tao Wang, Dan Song, Xuejuan Li, Yu Luo, Dianqiang Yang, Xiaoyan Liu, Xiaodan Kong, Yida Xing, Shulin Bi, Yan Zhang, Tao Hu, Yunyun Zhang, Shuang Dai, Zhiqiang Shao, Dahan Chen, Jinpao Hou, Esteban Ballestar, Jianchun Cai, Feng Zheng, James Y Yang Apr 2024

Mir-574-5p Activates Human Tlr8 To Promote Autoimmune Signaling And Lupus, Tao Wang, Dan Song, Xuejuan Li, Yu Luo, Dianqiang Yang, Xiaoyan Liu, Xiaodan Kong, Yida Xing, Shulin Bi, Yan Zhang, Tao Hu, Yunyun Zhang, Shuang Dai, Zhiqiang Shao, Dahan Chen, Jinpao Hou, Esteban Ballestar, Jianchun Cai, Feng Zheng, James Y Yang

Faculty, Staff and Student Publications

Endosomal single-stranded RNA-sensing Toll-like receptor-7/8 (TLR7/8) plays a pivotal role in inflammation and immune responses and autoimmune diseases. However, the mechanisms underlying the initiation of the TLR7/8-mediated autoimmune signaling remain to be fully elucidated. Here, we demonstrate that miR-574-5p is aberrantly upregulated in tissues of lupus prone mice and in the plasma of lupus patients, with its expression levels correlating with the disease activity. miR-574-5p binds to and activates human hTLR8 or its murine ortholog mTlr7 to elicit a series of MyD88-dependent immune and inflammatory responses. These responses include the overproduction of cytokines and interferons, the activation of STAT1 signaling …


Publisher Correction: Ndufs4 Regulates Cristae Remodeling In Diabetic Kidney Disease, Koki Mise, Jianyin Long, Daniel L Galvan, Zengchun Ye, Guizhen Fan, Rajesh Sharma, Irina I Serysheva, Travis I Moore, Collene R Jeter, M Anna Zal, Motoo Araki, Jun Wada, Paul T Schumacker, Benny H Chang, Farhad R Danesh Apr 2024

Publisher Correction: Ndufs4 Regulates Cristae Remodeling In Diabetic Kidney Disease, Koki Mise, Jianyin Long, Daniel L Galvan, Zengchun Ye, Guizhen Fan, Rajesh Sharma, Irina I Serysheva, Travis I Moore, Collene R Jeter, M Anna Zal, Motoo Araki, Jun Wada, Paul T Schumacker, Benny H Chang, Farhad R Danesh

Faculty, Staff and Students Publications

No abstract provided.


Arid1a Orchestrates Swi/Snf-Mediated Sequential Binding Of Transcription Factors With Arid1a Loss Driving Pre-Memory B Cell Fate And Lymphomagenesis, Darko Barisic, Christopher R Chin, Cem Meydan, Matt Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Xuehai Wang, Margot Sarkozy, Min Xia, Sandra E Carson, Santo Raggiri, Sonia Debek, Benedikt Pelzer, Ceyda Durmaz, Qing Deng, Priya Lakra, Martin Rivas, Christian Steidl, David W Scott, Andrew P Weng, Christopher E Mason, Michael R Green, Ari Melnick Apr 2024

Arid1a Orchestrates Swi/Snf-Mediated Sequential Binding Of Transcription Factors With Arid1a Loss Driving Pre-Memory B Cell Fate And Lymphomagenesis, Darko Barisic, Christopher R Chin, Cem Meydan, Matt Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Xuehai Wang, Margot Sarkozy, Min Xia, Sandra E Carson, Santo Raggiri, Sonia Debek, Benedikt Pelzer, Ceyda Durmaz, Qing Deng, Priya Lakra, Martin Rivas, Christian Steidl, David W Scott, Andrew P Weng, Christopher E Mason, Michael R Green, Ari Melnick

Faculty, Staff and Student Publications

ARID1A, a subunit of the canonical BAF nucleosome remodeling complex, is commonly mutated in lymphomas. We show that ARID1A orchestrates B cell fate during the germinal center (GC) response, facilitating cooperative and sequential binding of PU.1 and NF-kB at crucial genes for cytokine and CD40 signaling. The absence of ARID1A tilts GC cell fate toward immature IgM+CD80-PD-L2- memory B cells, known for their potential to re-enter new GCs. When combined with BCL2 oncogene, ARID1A haploinsufficiency hastens the progression of aggressive follicular lymphomas (FLs) in mice. Patients with FL with ARID1A-inactivating mutations preferentially display an immature memory B cell-like state with …


Transitional Care Medical House Call: A Pilot Project, Ron Billano Ordona Apr 2024

Transitional Care Medical House Call: A Pilot Project, Ron Billano Ordona

Dissertations

Vulnerable, homebound older adults are highly susceptible to unplanned 30-day hospital readmissions, which is costly for the healthcare system. As a result, health care expenditures for this population continue to rise. Studies have shown that transition of care programs, when complemented with home-based primary care delivery, may improve health care outcomes for this population.

The purpose of this quality improvement pilot project was to implement medical house calls as a component of transitional care management (TCM) and measure patient outcomes such as unplanned 30-day readmission rates and correlate predictors of readmission. As a secondary outcome, the project explored, tracked, and …


A Search For Intermediate-Mass Black Holes In Compact Stellar Systems Through Optical Emissions From Tidal Disruption Events, Richard T. Pomeroy, Mark A. Norris Apr 2024

A Search For Intermediate-Mass Black Holes In Compact Stellar Systems Through Optical Emissions From Tidal Disruption Events, Richard T. Pomeroy, Mark A. Norris

Physics & Astronomy Faculty Publications

Intermediate-mass black holes (IMBH) are expected to exist in globular clusters (GCs) and compact stellar systems (CSS) in general, but none have been conclusively detected. Tidal disruption events (TDEs), where a star is tidally disrupted by the gravitational field of a black hole, have been observed to occur around the supermassive black holes (SMBH) found at the centres of galaxies, and should also arise around IMBHs, especially in the dense stellar cores of CSS's. However, to date none have been observed in such environments. Using data from the Zwicky Transient Facility (ZTF) we search for TDEs associated with CSS, but …


The Aggregation Effect Of Offshore Mussel Farming On Pelagic Fishes, D Bridger, Mj Attrill, Se Rees, Ev Sheehan Apr 2024

The Aggregation Effect Of Offshore Mussel Farming On Pelagic Fishes, D Bridger, Mj Attrill, Se Rees, Ev Sheehan

School of Biological and Marine Sciences

The increase in hard artificial structures in the marine environment is contributing to ocean sprawl. As well as adding hard structure to the seabed, mussel aquaculture adds rope droppers and anchor lines to the water column, where such structure would otherwise be absent. This paper aims to monitor the effects of mussel headlines on the pelagic fish community over time, as well as to investigate whether there is an interaction between the age of cultivated mussels with the number of epibiota species and the abundance of pelagic fishes. Two surveys were carried out: a time series monitoring survey to assess …


Narrative Language Assessment And Intervention: Applications With Children With And Without Disabilities, Norah M. Almubark Apr 2024

Narrative Language Assessment And Intervention: Applications With Children With And Without Disabilities, Norah M. Almubark

USF Tampa Graduate Theses and Dissertations

Narrative is the art of conveying a sequence of causally and temporally linked events through monologic telling. Various functions can be served through narratives including sharing experiences, expressing ideas, providing entertainment, and imparting cultural or social values. Narrative language represents an authentic type of language that is useful for assessment and intervention because it can be analyzed according to content and form. The ability to use complex narrative language and produce quality narratives is associated with long-term academic and social benefits (Uccelli et al., 2019; Suggate et al, 2018). Given this crucial link, narrative language is suitable for child language …


Substantial Improvement In Photocatalysis Performance Of N-Tio2 Immobilized On Pmma: Exemplified By Inactivation Of Staphylococcus Aureus And Escherichia Coli, Li-Ting Yen, Chih-Huang Weng, Jing-Hua Tzeng, Ying-Chen Chen, Astrid R. Jacobson, Yao-Tung Lin Apr 2024

Substantial Improvement In Photocatalysis Performance Of N-Tio2 Immobilized On Pmma: Exemplified By Inactivation Of Staphylococcus Aureus And Escherichia Coli, Li-Ting Yen, Chih-Huang Weng, Jing-Hua Tzeng, Ying-Chen Chen, Astrid R. Jacobson, Yao-Tung Lin

Plants, Soils, and Climate Faculty Publications

Photocatalysis is an efficient process for degrading organic pollutants and inactivating pathogenic microorganisms. However, this process constantly suffers from turbidity shading and particle aggregation in a catalyst suspension system, thereby reducing its photocatalytic activity. Immobilizing the photocatalyst on the light-transmissible surface is a viable solution to the obstacles. So far, the photo-inactivation efficacy between the immobilized photocatalyst and suspension systems has yet to be compared and investigated. In this study, N-TiO2 (NT) immobilized on poly-methyl-methacrylate (PMMA) was fabricated via a dip-coating method, which has a high transmittance rate of 92 % - better than all of the previous works …


تسخير التكنولوجيا في تنمية صناعة الأثاث المحلي في فلسطين, إيهاب محمد أبوهنود Apr 2024

تسخير التكنولوجيا في تنمية صناعة الأثاث المحلي في فلسطين, إيهاب محمد أبوهنود

Journal of Arts and Social Sciences

الكلمات المفتاحيّة : أثاث معاصر؛ تكنولوجيا؛ البيئة المحيطة؛ فلسطين؛ صناعة.


(Mctaggart) حقيقة الزَّمان عند أرسطو ومَكْتَجارت, حسين حيدر علي إسماعيل Apr 2024

(Mctaggart) حقيقة الزَّمان عند أرسطو ومَكْتَجارت, حسين حيدر علي إسماعيل

Journal of Arts and Social Sciences

كلمات مفتاحية: الزمان؛ الحركة؛ الآن؛ الواقع؛ التناقض.


An Analysis On The Impact Of Normalized Difference Vegetation Index (Ndvi) Changes On The Land Surface Temperature (Lst) Using Satellite Imagery In The West Bank, Palestine An Analysis On The Impact Of Normalized Difference Vegetation Index (Ndvi) Changes On The Land Surface Temperature (Lst) Using Satellite Imagery In The West Bank, Palestine, Ahmed Ghodieh Apr 2024

An Analysis On The Impact Of Normalized Difference Vegetation Index (Ndvi) Changes On The Land Surface Temperature (Lst) Using Satellite Imagery In The West Bank, Palestine An Analysis On The Impact Of Normalized Difference Vegetation Index (Ndvi) Changes On The Land Surface Temperature (Lst) Using Satellite Imagery In The West Bank, Palestine, Ahmed Ghodieh

Journal of Arts and Social Sciences

Abstract


First-Time Market Goat, Ashley Longmore, Cheyenne Reid Apr 2024

First-Time Market Goat, Ashley Longmore, Cheyenne Reid

All Current Publications

This fact sheet is 4-H youth who are thinking about or have recently purchased their first 4-H goat. This fact sheet is a simple outline that provides information on selection, feeding, housing, basic care, and grooming.


Board Of Directors Meeting Minutes (April 8, 2024), Dmacc Apr 2024

Board Of Directors Meeting Minutes (April 8, 2024), Dmacc

Board of Directors Meeting Minutes

No abstract provided.


Connecting With Underserved Communities In Bristol: Insights From The Health Research Ambassador Project, Mari-Rose Kennedy, Carmel Mcgrath, Roy Kareem, Olivia Sweeney, Asia Yousif, Holly Ayres, Shoba Dawson, Aaruni Suresh, Andy Gibson Apr 2024

Connecting With Underserved Communities In Bristol: Insights From The Health Research Ambassador Project, Mari-Rose Kennedy, Carmel Mcgrath, Roy Kareem, Olivia Sweeney, Asia Yousif, Holly Ayres, Shoba Dawson, Aaruni Suresh, Andy Gibson

South West Clinical School Journal

#400WORDS: DELIVERING A RESEARCH SKILLED WORKFORCE SPECIAL EDITION


The George-Anne Reflector Magazine Newsletter, Georgia Southern University Apr 2024

The George-Anne Reflector Magazine Newsletter, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


The Roles Of Ferroptosis In Cancer: Tumor Suppression, Tumor Microenvironment, And Therapeutic Interventions, Guang Lei, Li Zhuang, Boyi Gan Apr 2024

The Roles Of Ferroptosis In Cancer: Tumor Suppression, Tumor Microenvironment, And Therapeutic Interventions, Guang Lei, Li Zhuang, Boyi Gan

Faculty, Staff and Student Publications

In cancer treatment, the recurrent challenge of inducing apoptosis through conventional therapeutic modalities, often thwarted by therapy resistance, emphasizes the critical need to explore alternative cell death pathways. Ferroptosis, an iron-dependent form of regulated cell death triggered by the lethal accumulation of lipid peroxides on cellular membranes, has emerged as one such promising frontier in oncology. Induction of ferroptosis not only suppresses tumor growth but also holds potential for augmenting immunotherapy responses and surmounting resistance to existing cancer therapies. This review navigates the role of ferroptosis in tumor suppression. Furthermore, we delve into the complex role of ferroptosis within the …


Smarca4 Is A Haploinsufficient B Cell Lymphoma Tumor Suppressor That Fine-Tunes Centrocyte Cell Fate Decisions, Qing Deng, Priya Lakra, Panhong Gou, Haopeng Yang, Cem Meydan, Matthew Teater, Christopher Chin, Wenchao Zhang, Tommy Dinh, Usama Hussein, Xubin Li, Estela Rojas, Weiguang Liu, Patrick K Reville, Atish Kizhakeyil, Darko Barisic, Sydney Parsons, Ashley Wilson, Jared Henderson, Brooks Scull, Channabasavaiah Gurumurthy, Francisco Vega, Amy Chadburn, Branko Cuglievan, Nader Kim El-Mallawany, Carl Allen, Christopher Mason, Ari Melnick, Michael R Green Apr 2024

Smarca4 Is A Haploinsufficient B Cell Lymphoma Tumor Suppressor That Fine-Tunes Centrocyte Cell Fate Decisions, Qing Deng, Priya Lakra, Panhong Gou, Haopeng Yang, Cem Meydan, Matthew Teater, Christopher Chin, Wenchao Zhang, Tommy Dinh, Usama Hussein, Xubin Li, Estela Rojas, Weiguang Liu, Patrick K Reville, Atish Kizhakeyil, Darko Barisic, Sydney Parsons, Ashley Wilson, Jared Henderson, Brooks Scull, Channabasavaiah Gurumurthy, Francisco Vega, Amy Chadburn, Branko Cuglievan, Nader Kim El-Mallawany, Carl Allen, Christopher Mason, Ari Melnick, Michael R Green

Faculty, Staff and Student Publications

SMARCA4 encodes one of two mutually exclusive ATPase subunits in the BRG/BRM associated factor (BAF) complex that is recruited by transcription factors (TFs) to drive chromatin accessibility and transcriptional activation. SMARCA4 is among the most recurrently mutated genes in human cancer, including ∼30% of germinal center (GC)-derived Burkitt lymphomas. In mice, GC-specific Smarca4 haploinsufficiency cooperated with MYC over-expression to drive lymphomagenesis. Furthermore, monoallelic Smarca4 deletion drove GC hyperplasia with centroblast polarization via significantly increased rates of centrocyte recycling to the dark zone. Mechanistically, Smarca4 loss reduced the activity of TFs that are activated in centrocytes to drive GC-exit, including SPI1 …


Arterial Spin-Labeling And Dsc Perfusion Metrics Improve Agreement In Neuroradiologists' Clinical Interpretations Of Posttreatment High-Grade Glioma Surveillance Mr Imaging-An Institutional Experience, Ghiam Yamin, Eric Tranvinh, Bryan A Lanzman, Elizabeth Tong, Syed S Hashmi, Chirag B Patel, Michael Iv Apr 2024

Arterial Spin-Labeling And Dsc Perfusion Metrics Improve Agreement In Neuroradiologists' Clinical Interpretations Of Posttreatment High-Grade Glioma Surveillance Mr Imaging-An Institutional Experience, Ghiam Yamin, Eric Tranvinh, Bryan A Lanzman, Elizabeth Tong, Syed S Hashmi, Chirag B Patel, Michael Iv

Faculty, Staff and Student Publications

Background and purpose: MR perfusion has shown value in the evaluation of posttreatment high-grade gliomas, but few studies have shown its impact on the consistency and confidence of neuroradiologists' interpretation in routine clinical practice. We evaluated the impact of adding MR perfusion metrics to conventional contrast-enhanced MR imaging in posttreatment high-grade glioma surveillance imaging.

Materials and methods: This retrospective study included 45 adults with high-grade gliomas who had posttreatment perfusion MR imaging. Four neuroradiologists assigned Brain Tumor Reporting and Data System scores for each examination on the basis of the interpretation of contrast-enhanced MR imaging and then after the addition …


A Structured Curriculum Supporting Biomedical Trainees’ Transition Into Independent Academic Positions And Early Career Success, Mabel Perez-Oquendo, Gabriele Romano, David P Farris, Varsha Gandhi, Ignacio I Wistuba, Robert E Tillman, Ryan Udan, Paolo Mangahas, Rama Soundararajan Apr 2024

A Structured Curriculum Supporting Biomedical Trainees’ Transition Into Independent Academic Positions And Early Career Success, Mabel Perez-Oquendo, Gabriele Romano, David P Farris, Varsha Gandhi, Ignacio I Wistuba, Robert E Tillman, Ryan Udan, Paolo Mangahas, Rama Soundararajan

Faculty, Staff and Student Publications

The United States government makes a substantial investment in biomedical training programs each year. However, for most trainees, these opportunities do not translate into career progression in academic research pathways. Only about one-fifth of postdoctoral fellows eventually secure a tenure-track faculty position, and even among these candidates, attrition is high. Although a number of factors govern career choices and career longevity, the transition from trainee to faculty is a challenging process and requires knowledge and skills that are not necessarily developed during a traditional university experience. Many postdoctoral fellows receive adequate training in research skills and scientific communication, but new …


Author Correction: Comparative Analysis Of Dimension Reduction Methods For Cytometry By Time-Of-Flight Data, Kaiwen Wang, Yuqiu Yang, Fangjiang Wu, Bing Song, Xinlei Wang, Tao Wang Apr 2024

Author Correction: Comparative Analysis Of Dimension Reduction Methods For Cytometry By Time-Of-Flight Data, Kaiwen Wang, Yuqiu Yang, Fangjiang Wu, Bing Song, Xinlei Wang, Tao Wang

Faculty, Staff and Student Publications

No abstract provided.


Single-Cell Systems Pharmacology Identifies Development-Driven Drug Response And Combination Therapy In B Cell Acute Lymphoblastic Leukemia, Xin Huang, Yizhen Li, Jingliao Zhang, Lei Yan, Huanbin Zhao, Liang Ding, Sheetal Bhatara, Xu Yang, Satoshi Yoshimura, Wenjian Yang, Seth E Karol, Hiroto Inaba, Charles Mullighan, Mark Litzow, Xiaofan Zhu, Yingchi Zhang, Wendy Stock, Nitin Jain, Elias Jabbour, Steven M Kornblau, Marina Konopleva, Ching-Hon Pui, Elisabeth Paietta, William Evans, Jiyang Yu, Jun J Yang Apr 2024

Single-Cell Systems Pharmacology Identifies Development-Driven Drug Response And Combination Therapy In B Cell Acute Lymphoblastic Leukemia, Xin Huang, Yizhen Li, Jingliao Zhang, Lei Yan, Huanbin Zhao, Liang Ding, Sheetal Bhatara, Xu Yang, Satoshi Yoshimura, Wenjian Yang, Seth E Karol, Hiroto Inaba, Charles Mullighan, Mark Litzow, Xiaofan Zhu, Yingchi Zhang, Wendy Stock, Nitin Jain, Elias Jabbour, Steven M Kornblau, Marina Konopleva, Ching-Hon Pui, Elisabeth Paietta, William Evans, Jiyang Yu, Jun J Yang

Faculty, Staff and Student Publications

Leukemia can arise at various stages of the hematopoietic differentiation hierarchy, but the impact of developmental arrest on drug sensitivity is unclear. Applying network-based analyses to single-cell transcriptomes of human B cells, we define genome-wide signaling circuitry for each B cell differentiation stage. Using this reference, we comprehensively map the developmental states of B cell acute lymphoblastic leukemia (B-ALL), revealing its strong correlation with sensitivity to asparaginase, a commonly used chemotherapeutic agent. Single-cell multi-omics analyses of primary B-ALL blasts reveal marked intra-leukemia heterogeneity in asparaginase response: resistance is linked to pre-pro-B-like cells, with sensitivity associated with the pro-B-like population. By …


Mlotok V. 63 Co. Llc Apr 2024

Mlotok V. 63 Co. Llc

All Decisions

In this case, the landlord seeks partial summary judgment to dismiss the tenant's claims of rent stabilization and willful rent overcharge. The court grants the landlord's motion, finding that the apartment was lawfully deregulated due to the expiration of J-51 tax benefits and individual apartment improvements. The court also allows the landlord to amend its counterclaim for unpaid rent, ultimately awarding the landlord $9,040.00 in rent owed.


The Music Theory Booklet Balliol 173a, Fols. 74r–81v: Scribal Organisation Of An Early Medieval Theory Miscellany, C. Matthew Balensuela Apr 2024

The Music Theory Booklet Balliol 173a, Fols. 74r–81v: Scribal Organisation Of An Early Medieval Theory Miscellany, C. Matthew Balensuela

Music Faculty publications

Using evidence of the quality of vellum, fascicle structure, scribal hands and illustrations, this article argues that the first fascicle of the music portion of Oxford, Balliol College, 173A (fols. 74–81) is a self-standing booklet, perhaps created to teach a scribe the basics of music theory and how to arrange text while leaving space for illustrations or examples. A new fascicle structure of the gathering is proposed that accounts for a previously unrecognised missing folio. An analysis of the contents of the gathering demonstrates that the theory booklet is a compilatio, with portions of the Musica disciplina (or it sources) …