Evaluation Of An Automated Von Willebrand Factor Glycoprotein Ibm Activity Assay Compared With 3 Alternative Von Willebrand Factor Activity Assays, Kenneth D Friedman, Martina Böhm-Weigert, Nicole Desimone, Dennis J Dietzen, Charles Eby, Cynthia Flickinger, Walter Hoyer, Mareike Kahl, Kandice Kottke-Marchant, Thomas L Ortel, Jürgen Patzke, Steven W Pipe, Morgan Stuart, Ayse Anil Timur, Ravindra Sarode

2020-Current year OA Pubs

BACKGROUND: To overcome deficiencies of the traditional von Willebrand factor (VWF) ristocetin cofactor activity assay (VWF:RCo), several automated assays for VWF platelet-binding activity have been developed. Information on the performance of these assays and their diagnostic utility remains limited.

OBJECTIVES: To validate the VWF:glycoprotein IbM assay INNOVANCE VWF Ac and compare it with an automated VWF:RCo assay as well as with an automated assay and a manual VWF:Ab assay and to generate reference ranges and analyze reproducibility of the VWF:glycoprotein IbM assay.

METHODS: Clinical sites enrolled healthy subjects and patients representing the intended use population; VWF activity assays were performed, …

My Anesthesia Choice-Hf: Development And Preliminary Testing Of A Tool To Facilitate Conversations About Anesthesia For Hip Fracture Surgery, Mark D Neuman, Glyn Elwyn, Veena Graff, Viktoria Schmitz, Mary C Politi

2020-Current year OA Pubs

BACKGROUND: Patients often desire involvement in anesthesia decisions, yet clinicians rarely explain anesthesia options or elicit preferences. We developed My Anesthesia Choice-Hip Fracture, a conversation aid about anesthesia options for hip fracture surgery and tested its preliminary efficacy and acceptability.

METHODS: We developed a 1-page, tabular format, plain-language conversation aid with feedback from anesthesiologists, decision scientists, and community advisors. We conducted an online survey of English-speaking adults aged 50 and older. Participants imagined choosing between spinal and general anesthesia for hip fracture surgery. Before and after viewing the aid, participants answered a series of questions regarding key outcomes, including decisional …

Understanding Medical Students' Perceived Readiness To Serve As Culturally Competent Practitioners, Michel'le Janae Bryant

Seton Hall University Dissertations and Theses (ETDs)

Background: The US population is more culturally diverse than ever. Although advancements have been made in improving the nation’s overall health, health disparities continue among different racial and ethnic groups. To promote person-centered care practices, medical students must be ready to serve diverse patient populations and provide equitable care. Despite their training, some medical students report feeling unprepared to treat diverse patient populations, potentially impacting their clinical practice and patient care outcomes.

Purpose: This study’s purpose was to explore the perceived readiness of final-year medical students in the US to provide culturally competent care utilizing the Readiness Theory and The …

A Word From The Writing Team (May 2024), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Join Us for Our Virtual Writing Retreat on May 3rd
• Save the Date for the 16th Annual Jefferson Faculty Days: June 5th & 6th
• Scott Memorial Library Archive Renovations Are Done—Come See!
• Thomas Jefferson University Has Updated Its Mission Statement
• Publication Spotlight
• Jefferson's AI Library Guide is Available on the Library Website
• The OPWPC Canvas Page Offers Helpful Tools

Application Of Microphytes For Soil Reclamation, Lalit Saini, Hina Upadhyay, Arindam Chakraborty

Research Publications (2021 to 2025)

Microphytes incorporate several characteristics that are becoming increasingly important in a complex farming setting and the process of land reclamation. Microalgae/microphytes boost soil productivity and structure by adding minerals and improving microbial soil quality metrics and nutrient cycling. Protecting plants from disease, producing phytohormones and other bioactive compounds, and associating with plant roots are the ways through which microalgae contribute to plant development. These results are significant as they could lead to further advancements in the discovery of substances that can boost growth or the development of crops that do not need nitrogen. Microalgae have massive untapped capabilities as natural …

Arkib Universiti Sebagai Repositori Memori Institusi / Siti Mawarni Salim, Noorsuzila Mohamad, Nor Edzan Che Nasir, Salim Siti Mawarni, Mohamad Noorsuzila, Che Nasir Nor Edzan

Research Publications (2021 to 2025)

Arkib universiti merupakan repositori untuk rekod, penerbitan dan artifak sesebuah universiti. Tanggungjawab untuk membangun dan mengurus arkib universiti lazimnya diserahkan kepada perpustakaan universiti berkenaan. Buat masa kini, kebanyakan universiti tertua mempunyai arkib universiti tersendiri seperti Harvard University Archives, Archives at Yale, University of Cambridge University Archives, Oxford University Archives, Kyoto University Archives, Osaka University Archive Repository, Museum of Peking University History, Tsinghua University History Museum dan banyak lagi. Di Malaysia, terdapat 20 buah universiti awam dan pelbagai jumlah universiti swasta, kampus universiti luar negara, kolej, politeknik, kolej komuniti dan kolej swasta. Sehingga kini, tiada rekod rasmi bilangan institusi pengajian tinggi …

Australian Non-Perennial Rivers: Global Lessons And Research Opportunities, Margaret Shanafield, Melanie Blanchette, Edoardo Daly, Naomi Wells, Ryan M. Burrows, Kathryn Korbel, Gabriel C. Rau, Sarah Bourke, Gresley Wakelin-King, Aleicia Holland, Timothy Ralph, Gavan Mcgrath, Belinda Robson, Keirnan Fowler, Martin S. Andersen, Songyan Yu, Christopher S. Jones, Nathan Waltham, Eddie W. Banks, Alissa Flatley, Catherine Leigh, Sally Maxwell, Andre Siebers, Nick Bond, Leah Beesley, Grant Hose, Jordan Iles, Ian Cartwright, Michael Reid, Thiaggo De Castro Tayer, Clément Duvert

Research outputs 2022 to 2026

Non-perennial rivers are valuable water resources that support millions of humans globally, as well as unique riparian ecosystems. In Australia, the Earth's driest inhabited continent, over 70% of rivers are non-perennial due to a combination of ancient landscape, dry climates, highly variable rainfall regimes, and human interventions that have altered riverine environments. Here, we review Australian non-perennial river research incorporating geomorphology, hydrology, biogeochemistry, ecology, and Indigenous knowledges. The dominant research themes in Australia were drought, floods, salinity, dryland ecology, and water management. Future research will likely follow these themes but must address emerging threats to river systems due to climate …

Scaling Up Cooperative Multi-Agent Reinforcement Learning Systems, Minghong Geng

Research Collection School Of Computing and Information Systems

Cooperative multi-agent reinforcement learning methods aim to learn effective collaborative behaviours of multiple agents performing complex tasks. However, existing MARL methods are commonly proposed for fairly small-scale multi-agent benchmark problems, wherein both the number of agents and the length of the time horizons are typically restricted. My initial work investigates hierarchical controls of multi-agent systems, where a unified overarching framework coordinates multiple smaller multi-agent subsystems, tackling complex, long-horizon tasks that involve multiple objectives. Addressing another critical need in the field, my research introduces a comprehensive benchmark for evaluating MARL methods in long-horizon, multi-agent, and multi-objective scenarios. This benchmark aims to …

Q-Learning Based Framework For Solving The Stochastic E-Waste Collection Problem, Dang Viet Anh Nguyen, Aldy Gunawan, Mustafa Misir, Pieter Vansteenwegen

Research Collection School Of Computing and Information Systems

Electrical and Electronic Equipment (EEE) has evolved into a gateway for accessing technological innovations. However, EEE imposes substantial pressure on the environment due to the shortened life cycles. E-waste encompasses discarded EEE and its components which are no longer in use. This study focuses on the e-waste collection problem and models it as a Vehicle Routing Problem with a heterogeneous fleet and a multi-period planning problem with time windows as well as stochastic travel times. Two different Q-learning-based methods are designed to enhance the search procedure for finding solutions. The first method involves utilizing the state-action value to determine the …

Ublade: Efficient Batch Processing For Uncertainty Graph Queries, Siyuan Yao, Yuchen Li, Shixuan Sun, Jiaxin Jiang, Bingsheng He

Research Collection School Of Computing and Information Systems

The study of uncertain graphs is crucial in diverse fields, including but not limited to protein interaction analysis, viral marketing, and network reliability. Processing queries on uncertain graphs presents formidable challenges due to the vast probabilistic space they encapsulate. While existing systems employ batch processing to address these challenges, their performance is often compromised by the suboptimal selection of parallel graph traversal methods, the excessive costs in random number generation, and additional sampling-loads intrinsic to batch processing. In this paper, we introduce uBlade, an efficient batch-processing framework for uncertain graph queries on multi-core CPUs. uBlade utilizes the work-efficient graph traversal, …

Explaining Sequences Of Actions In Multi-Agent Deep Reinforcement Learning Models, Phyo Wai Khaing, Minghong Geng, Shubham Pateria, Budhitama Subagdja, Ah-Hwee Tan

Research Collection School Of Computing and Information Systems

This paper introduces a method to explain MADRL agents’ behaviors by abstracting their actions into high-level strategies. Particularly, a spatio-temporal neural network model is applied to encode the agents’ sequences of actions as memory episodes wherein an aggregating memory retrieval can generalize them into a concise abstract representation of collective strategies. To assess the effectiveness of our method, we applied it to explain the actions of QMIX MADRL agents playing a StarCraft Multi-agent Challenge (SMAC) video game. A user study on the perceived explainability of the extracted strategies indicates that our method can provide comprehensible explanations at various levels of …

Benchmarking Marl On Long Horizon Sequential Multi-Objective Tasks, Minghong Geng, Shubham Pateria, Budhitama Subagdja, Ah-Hwee Tan

Research Collection School Of Computing and Information Systems

Current MARL benchmarks fall short in simulating realistic scenarios, particularly those involving long action sequences with sequential tasks and multiple conflicting objectives. Addressing this gap, we introduce Multi-Objective SMAC (MOSMAC), a novel MARL benchmark tailored to assess MARL methods on tasks with varying time horizons and multiple objectives. Each MOSMAC task contains one or multiple sequential subtasks. Agents are required to simultaneously balance between two objectives - combat and navigation - to successfully complete each subtask. Our evaluation of nine state-of-the-art MARL algorithms reveals that MOSMAC presents substantial challenges to many state-of-the-art MARL methods and effectively fills a critical gap …

Enabling Roll-Up And Drill-Down Operations In News Exploration With Knowledge Graphs For Due Diligence And Risk Management, Sha Wang, Yuchen Li, Hanhua Xiao, Zhifeng Bao, Yanfei Dong

Research Collection School Of Computing and Information Systems

Efficient news exploration is crucial in real-world applications, particularly within the financial sector, where numerous control and risk assessment tasks rely on the analysis of public news reports. The current processes in this domain predominantly rely on manual efforts, often involving keyword-based searches and the compilation of extensive keyword lists. In this paper, we introduce NCEXPLORER, a framework designed with OLAP-like operations to enhance the news exploration experience. NCEXPLORER empowers users to use roll-up operations for a broader content overview and drill-down operations for detailed insights. These operations are achieved through integration with external knowledge graphs (KGs), encompassing both fact-based …

Learning Nighttime Semantic Segmentation The Hard Way, Wenxi Liu, Jiaxin Cai, Qi Li, Chenyang Liao, Jingjing Cao, Shengfeng He, Yuanlong Yu

Research Collection School Of Computing and Information Systems

Nighttime semantic segmentation is an important but challenging research problem for autonomous driving. The major challenges lie in the small objects or regions from the under-/over-exposed areas or suffer from motion blur caused by the camera deployed on moving vehicles. To resolve this, we propose a novel hard- class-aware module that bridges the main network for full-class segmentation and the hard-class network for segmenting aforementioned hard-class objects. In specific, it exploits the shared focus of hard-class objects from the dual-stream network, enabling the contextual information flow to guide the model to concentrate on the pixels that are hard to classify. …

Text-Attributed Graph Representation Learning : Methods, Applications, And Challenges, Ce Zhang, Menglin Yang, Rex Ying, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

Text documents are usually connected in a graph structure, resulting in an important class of data named text-attributed graph, e.g., paper citation graph and Web page hyperlink graph. On the one hand, Graph Neural Networks (GNNs) consider text in each document as general vertex attribute and do not specifically deal with text data. On the other hand, Pre-trained Language Models (PLMs) and Topic Models (TMs) learn effective document embeddings. However, most models focus on text content in each single document only, ignoring link adjacency across documents. The above two challenges motivate the development of text-attributed graph representation learning, combining GNNs …

Cornac-Ab : An Open-Source Recommendation Framework With Native A/B Testing Integration, Rong Sheng Ong, Quoc Tuan Truong, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

Recommender systems significantly impact user experience across diverse domains, yet existing frameworks often prioritize offline evaluation metrics, neglecting the crucial integration of A/B testing for forward-looking assessments. In response, this paper introduces a new framework seamlessly incorporating A/B testing into the Cornac recommendation library. Leveraging a diverse collection of model implementations in Cornac, our framework enables effortless A/B testing experiment setup from offline trained models. We introduce a carefully designed dashboard and a robust backend for efficient logging and analysis of user feedback. This not only streamlines the A/B testing process but also enhances the evaluation of recommendation models in …

Term Importance For Transformer-Based Qa Retrieval : A Case Study Of Stackexchange, Bryan Zhi Yang Tan, Hady W. Lauw

Research Collection School Of Computing and Information Systems

Question-answering (QA) retrieval is the task of retrieving the most relevant answer to a given question from a collection of answers. Various approaches to QA retrieval have been developed recently. One successful and popular model is Contextualized Late Interaction over BERT (ColBERT), a transformer-based approach that adopts a query-document scoring mechanism that retains the granularity of transformer matching, whilst improving on efficiency. However, one key limitation is that it requires further fine-tuning for new query or collection types. In this work, we explore and propose several non-parametric retrieval augmentation methods based on explicit signals of term importance that improve over …

Baffle : Hiding Backdoors In Offline Reinforcement Learning Datasets, Chen Gong, Zhou Yang, Yunpeng Bai, Junda He, Jieke Shi, Kecen Li, Arunesh Sinha, Bowen Xu, Xinwen Hou, David Lo, Tianhao Wang

Research Collection School Of Computing and Information Systems

Reinforcement learning (RL) makes an agent learn from trial-and-error experiences gathered during the interaction with the environment. Recently, offline RL has become a popular RL paradigm because it saves the interactions with environments. In offline RL, data providers share large pre-collected datasets, and others can train high-quality agents without interacting with the environments. This paradigm has demonstrated effectiveness in critical tasks like robot control, autonomous driving, etc. However, less attention is paid to investigating the security threats to the offline RL system. This paper focuses on backdoor attacks, where some perturbations are added to the data (observations) such that given …

Online Control Of Adaptive Large Neighborhood Search Using Deep Reinforcement Learning, Reijnen Reijnen, Yingqian Zhang, Hoong Chuin Lau, Zaharah Bukhsh

Research Collection School Of Computing and Information Systems

The Adaptive Large Neighborhood Search (ALNS) algorithm has shown considerable success in solving combinatorial optimization problems (COPs). Nonetheless, the performance of ALNS relies on the proper configuration of its selection and acceptance parameters, which is known to be a complex and resource-intensive task. To address this, we introduce a Deep Reinforcement Learning (DRL) based approach called DR-ALNS that selects operators, adjusts parameters, and controls the acceptance criterion throughout the search. The proposed method aims to learn, based on the state of the search, to configure ALNS for the next iteration to yield more effective solutions for the given optimization problem. …

Factored Mdp Based Moving Target Defense With Dynamic Threat Modeling, Megha Bose, Praveen Paruchuri, Akshat Kumar

Research Collection School Of Computing and Information Systems

Moving Target Defense (MTD) has emerged as a proactive defense framework to counteract ever-changing cyber threats. Existing approaches often make assumptions about attacker-side knowledge and behavior, potentially resulting in suboptimal defense. This paper introduces a novel MTD approach, leveraging a Markov Decision Process (MDP) model that eliminates the need for prior knowledge about attacker intentions or payoffs. Our framework seamlessly integrates real-time attacker responses into the defender's MDP using a dynamic Bayesian network. We use a factored MDP model to enable a more comprehensive and realistic representation of the system having multiple switchable aspects and also accommodate incremental updates of …

Difference Of Convex Functions Programming For Policy Optimization In Reinforcement Learning, Akshat Kumar

Research Collection School Of Computing and Information Systems

We formulate the problem of optimizing an agent's policy within the Markov decision process (MDP) model as a difference-of-convex functions (DC) program. The DC perspective enables optimizing the policy iteratively where each iteration constructs an easier-to-optimize lower bound on the value function using the well known concave-convex procedure. We show that several popular policy gradient based deep RL algorithms (both for discrete and continuous state, action spaces, and stochastic/deterministic policies) such as actor-critic, deterministic policy gradient (DPG), and soft actor critic (SAC) can be derived from the DC perspective. Additionally, the DC formulation enables more sample efficient learning approaches by …

Escaping Saddle Points In Heterogeneous Federated Learning Via Distributed Sgd With Communication Compression, Sijin Chen, Zhize Li, Yuejie Chi

Research Collection School Of Computing and Information Systems

We consider the problem of finding second-order stationary points in the optimization of heterogeneous federated learning (FL). Previous works in FL mostly focus on first-order convergence guarantees, which do not rule out the scenario of unstable saddle points. Meanwhile, it is a key bottleneck of FL to achieve communication efficiency without compensating the learning accuracy, especially when local data are highly heterogeneous across different clients. Given this, we propose a novel algorithm PowerEF-SGD that only communicates compressed information via a novel error-feedback scheme. To our knowledge, PowerEF-SGD is the first distributed and compressed SGD algorithm that provably escapes saddle points …

Make Revocation Cheaper: Hardware-Based Revocable Attribute-Based Encryption, Xiaoguo Li, Guomin Yang, Tao Xiang, Shengmin Xu, Bowen Zhao, Robert H. Deng, Hwee Hwa Pang

Research Collection School Of Computing and Information Systems

As an advanced one-to-many public key encryption system, attribute-based encryption (ABE) is widely believed to be a promising technology for achieving flexible and fine-grained access control of encrypted data on untrusted storage servers (e.g., public cloud servers). However, user revocation in ABE is a critical but challenging problem, and designing efficient revocable ABE has been an active research topic in the past decade. Almost all the existing revocable ABE schemes incorporate a timestamp in the encryption algorithm such that revoked users cannot decrypt ciphertexts generated in future time intervals. To prevent revoked users from decrypting past ciphertexts, the storage server …

A Survey On Searchable Symmetric Encryption, Feng Li, Jianfeng Ma, Yinbin Miao, Ximeng Liu, Jianting Ning, Robert H. Deng

Research Collection School Of Computing and Information Systems

Outsourcing data to the cloud has become prevalent, so Searchable Symmetric Encryption (SSE), one of the methods for protecting outsourced data, has arisen widespread interest. Moreover, many novel technologies and theories have emerged, especially for the attacks on SSE and privacy-preserving. But most surveys related to SSE concentrate on one aspect (e.g., single keyword search, fuzzy keyword search) or lack in-depth analysis. Therefore, we revisit the existing work and conduct a comprehensive analysis and summary. We provide an overview of state-of-the-art in SSE and focus on the privacy it can protect. Generally, (1) we study the work of the past …

Navigating Real-World Challenges: A Quadruped Robot Guiding System For Visually Impaired People In Diverse Environments, Shaojun Cai, Ashwin Ram, Zhengtai Gou, Mohd Alqama Wasim Shaikh, Yu-An Chen, Yingjia Wan, Kotaro Hara, Shengdong Zhao, David Hsu

Research Collection School Of Computing and Information Systems

Blind and Visually Impaired (BVI) people find challenges in navigating unfamiliar environments, even using assistive tools such as white canes or smart devices. Increasingly affordable quadruped robots offer us opportunities to design autonomous guides that could improve how BVI people find ways around unfamiliar environments and maneuver therein. In this work, we designed RDog, a quadruped robot guiding system that supports BVI individuals’ navigation and obstacle avoidance in indoor and outdoor environments. RDog combines an advanced mapping and navigation system to guide users with force feedback and preemptive voice feedback. Using this robot as an evaluation apparatus, we conducted experiments …

Analyzing And Revivifying Function Signature Inference Using Deep Learning, Yan Lin, Trisha Singhal, Debin Gao, David Lo

Research Collection School Of Computing and Information Systems

Function signature plays an important role in binary analysis and security enhancement, with typical examples in bug finding and control-flow integrity enforcement. However, recovery of function signatures by static binary analysis is challenging since crucial information vital for such recovery is stripped off during compilation. Although function signature recovery using deep learning (DL) is proposed in an effort to handle such challenges, the reported accuracy is low for binaries compiled with optimizations. In this paper, we first perform a systematic study to quantify the extent to which compiler optimizations (negatively) impact the accuracy of existing DL techniques based on Recurrent …

Learning To Generate Explainable Stock Predictions Using Self‑Reflective Large Language Models, Kelvin J.L. Koa, Yunshan Ma, Ritchie Ng, Tat‑Seng Chua

Research Collection School Of Computing and Information Systems

Explaining stock predictions is generally a difficult task for traditional non-generative deep learning models, where explanations are limited to visualizing the attention weights on important texts. Today, Large Language Models (LLMs) present a solution to this problem, given their known capabilities to generate human-readable explanations for their decision-making process. However, the task of stock prediction remains challenging for LLMs, as it requires the ability to weigh the varying impacts of chaotic social texts on stock prices. The problem gets progressively harder with the introduction of the explanation component, which requires LLMs to explain verbally why certain factors are more important …

Fashionregen: Llm‑Empowered Fashion Report Generation, Yujuan Ding, Yunshan Ma, Wenqi Fan, Yige Yao, Tat‑Seng Chua, Qing Li

Research Collection School Of Computing and Information Systems

Fashion analysis refers to the process of examining and evaluating trends, styles, and elements within the fashion industry to understand and interpret its current state, generating fashion reports. It is traditionally performed by fashion professionals based on their expertise and experience, which requires high labour cost and may also produce biased results for relying heavily on a small group of people. In this paper, to tackle the Fashion Report Generation (FashionReGen) task, we propose an intelligent Fashion Analyzing and Reporting system based the advanced Large Language Models (LLMs), debbed as GPT-FAR. Specifically, it tries to deliver FashionReGen based on effective …

Reinforcement Retrieval Leveraging Fine-Grained Feedback For Fact Checking News Claims With Black-Box Llm, Xuan Zhang, Wei Gao

Research Collection School Of Computing and Information Systems

Retrieval-augmented language models have exhibited promising performance across various areas of natural language processing (NLP), including fact-critical tasks. However, due to the black-box nature of advanced large language models (LLMs) and the non-retrieval-oriented supervision signal of specific tasks, the training of retrieval model faces significant challenges under the setting of black-box LLM. We propose an approach leveraging Fine-grained Feedback with Reinforcement Retrieval (FFRR) to enhance fact-checking on news claims by using black-box LLM. FFRR adopts a two-level strategy to gather fine-grained feedback from the LLM, which serves as a reward for optimizing the retrieval policy, by rating the retrieved documents …

Towards Explainable Harmful Meme Detection Through Multimodal Debate Between Large Language Models, Hongzhan Lin, Ziyang Luo, Wei Gao, Jing Ma, Bo Wang, Ruichao Yang

Research Collection School Of Computing and Information Systems

The age of social media is flooded with Internet memes, necessitating a clear grasp and effective identification of harmful ones. This task presents a significant challenge due to the implicit meaning embedded in memes, which is not explicitly conveyed through the surface text and image. However, existing harmful meme detection methods do not present readable explanations that unveil such implicit meaning to support their detection decisions. In this paper, we propose an explainable approach to detect harmful memes, achieved through reasoning over conflicting rationales from both harmless and harmful positions. Specifically, inspired by the powerful capacity of Large Language Models …