Digital Commons Network^™

Crispr-Cas-Based Activation Of Ppargc1a Boosts Endogenous Mitochondria And Enhances Cardiac Function After Myocardial Infarction, Mario Escobar, Saad A Malik, Mira A Srinivasa, Miguel A Mendez-Sosa, Jessica M Miller, Samantha L Lydon, Sandy N Luong, Pretty R Mathew, Riham R E Abouleisa, Suridh Chakravarty, Saliha Pathan, Tamer M A Mohamed, Ravi K Ghanta, Isaac B Hilton

Faculty, Staff and Students Publications

Insufficient energy supply due to impaired mitochondria has emerged as a key pathological factor in the development of heart failure (HF) after myocardial infarction (MI). Unfortunately, no current therapeutic strategies directly augment myocardial energy production. While mitochondrial biogenesis is orchestrated by the activity of multiple genes, activation of PPARGC1A, a key regulator, can increase cellular mitochondria; however, supraphysiological levels of PPARGC1A result in adverse tissue remodeling and heart dysfunction. CRISPR activation (CRISPRa) technologies present a unique opportunity to address these shortcomings, as they enable tunable control over endogenous target gene expression. Here, we demonstrate that transcriptional activation of PPARGC1A using …

Emotional Intelligence And Teamwork In A Ship’S Bridge : A Proposed Training Framework For Upskilling, Sofia Kallou, Nikitas Nikitakos, Dimitrios A. Papachristos, Dimitrios Dalaklis, Momoko Kitada

Articles

The notion that computers equipped with software and artificial intelligence (AI) applications can effectively replace human intelligence is under the existing paradigm of operations. This is the leading facilitator of task automation on board a ship to fulfill various jobs and is often supported by numerous scientists/academics who contribute to gaining today’s momentum in public opinion. The discourse of Industry 4.0 in the maritime domain, however, tends to focus heavily on technological contexts and overlooks socio-economic contexts. This gap is evident in the strong emphasis on technical and digital skills for future maritime professionals. This paper, therefore, argues that the …

Concept Analysis In Occupational Therapy Research: Exploring Approaches And Discipline-Specific Considerations, Patricia Schofield, Tanja Krizaj, Kirsty Thomas

School of Nursing and Midwifery

PurposeThis paper aims to explore the use and considerations needed for conducting a concept analysis within occupational therapy research. Concept analysis is a popular analytical research tool used with the methodology providing firmer definitions of ambiguous concepts.Design/methodology/approachAn exploration into the use of concept analysis within occupational therapy research. Discussing current approaches of concept analysis and the implementation of this within occupational therapy research.FindingsConcept analysis within occupational therapy research requires further consideration. Current research is favouring one approach when completing a concept analysis that leads to common flaws within the methodology.Originality/valueFurther consideration is required to the approaches followed when completing a …

Fsec Meeting Minutes June 3, 2026, University Of Rhode Island Faculty Senate

Faculty Senate Executive Committee Minutes

No abstract provided.

Residential Ai Data Centers: Security, Privacy, And Governance Concerns, Alan Saquella

Publications

The concept of placing mini data centers and distributed AI computer nodes inside residential homes may appear innovative from an energy efficiency perspective, but it introduces significant security, privacy, governance, and liability concerns. What is effectively occurring is the expansion of commercial and potentially critical infrastructure into lightly protected residential environments.

Once a residence becomes part of a distributed computer grid supporting hyper-scalers, AI providers, or enterprise workloads, the home is no longer simply a private residence. It becomes a commercial technology asset, a potential cyber target, and even a physical target. A distributed network of thousands of residential nodes …

Maya Roots, Erin Schmidt, Megu Kanzawa

Computer Science and Engineering Senior Theses

This project focused on the continued development of Maya Roots, a mobile and web-based platform designed for farmers in Tahcabo: a rural agricultural community located in Yucatán, Mexico. Yucatán faces unique agricultural challenges due to its karst limestone terrain and highly variable land conditions that can significantly impact farming outcomes. At the same time, traditional agricultural knowledge such as Milpa farming practices is increasingly at risk of being lost across generations. These environmental and cultural challenges highlighted the need for a portable, accessible system that could preserve agricultural knowledge, improve access to geospatial information, and strengthen communication between farmers and …

Dual Language Immersion In Utah Schools: Examining Experiences And Access To Improve Sustainability, Melissa Catherine Jensen Kimball

Theses and Dissertations

Dual language immersion (DLI) programs can impact students in many ways. Multiple researchers have studied the effects of these programs and have found numerous benefits. However, there is little published information on the actual experiences of individuals in schools with a DLI program, including those who are involved in the program and those who were a part of DLI school communities but not directly involved in the program. A. Hawks, J. Rowley, D. Stovall, and their respective thesis and dissertation committees created a survey to better understand the current perspectives of administrators, parents, teachers, and other school staff on these …

2026-06-03 Pope’S First Encyclical Cautions Catholics On Ai, Kean Mathis

The Spectator Online

No abstract provided.

2026-06-03 Nursing Students To Graduate Without Traditional Stoles, Maya Deguzman

The Spectator Online

No abstract provided.

2026-06-03 Maybe We Should Take Less Pictures: On Photography And Possession, Hannah Mwangi

The Spectator Online

No abstract provided.

The Sustainable Autonomy Framework: Explaining Autonomy In Aceh And Southern Yemen, Abdulsalam Saad, Arie Kusuma Paksi

Jurnal Politik

This article examines why post-conflict autonomy consolidates into durable self-governance in some cases while remaining fragile and externally dependent in others. While Aceh has maintained stable self-governance since the 2005 Helsinki Agreement, Yemen’s Southern Transitional Council remains a fragmented authority sustained by external patronage. To explain this divergence, the article develops the Sustainable Autonomy Framework (SAF) and asks: under what conditions does post-conflict autonomy become viable and sustainable? The SAF argues that durability depends on the alignment of three mutually reinforcing pillars: elite legitimacy, resource sovereignty, and mediation credibility. Using a most-similar systems comparison of Aceh’s Free Aceh Movement and …

Vitamin D–Amp Axis In Host Defense Against Fungal Infections, Nuraly S. Akimbekov, Ilya Digel, Svetlana K. Sakhanova, Kuanysh Tastambek, Dinara K. Sherelkhan, Mohammed S. Razzaque

School of Medicine Publications

Vitamin D–mediated regulation of antimicrobial peptides (AMPs) is an important focus in innate immunology and is aimed at elucidating the role of vitamin D in enhancing antimicrobial defense. AMPs are short protein chains that serve as a first line of defense against invading pathogens, including fungi, bacteria and viruses. Unlike conventional antibiotics, AMPs are produced endogenously and are less likely to induce antimicrobial resistance, making them promising candidates for treating infections caused by drug-resistant pathogens. Studies indicate that optimal vitamin D levels are essential for activating antimicrobial pathways and regulating AMPs that target multiple fungal pathogens. This article summarizes recent …

From Performance To Practice: Knowledge-Distilled Segmentator For On-Premises Clinical Workflows, Zhongming Zhao, Xiaoqian Jiang, Yu-Chun Hsu

Faculty, Staff and Student Publications

Deploying medical image segmentation models in routine clinical workflows is often constrained by on-premises infrastructure, where computational resources are fixed and cloud-based inference may be restricted by governance and security policies. While high-capacity models achieve strong segmentation accuracy, their computational demands hinder practical deployment and long-term maintainability in hospital environments. We present a deployment-oriented framework that leverages knowledge distillation to translate a high-performing segmentation model into a scalable family of compact student models without modifying the inference pipeline. The framework is primarily evaluated on nnU-Net, with additional validation across transformer and heterogeneous teacher–student architectures. The proposed approach preserves architectural compatibility …

Life Sustaining Well-Being Practices And Physiological Health Among Black Men, Dakota W. Cintron, Monique N. Golden, Jennifer M. Boylan, Julia K. Boehm, Tomiko Yoneda, Hebi Wang, Erik M. Hines, James L. Moore Iii

Psychology Faculty Articles and Research

Objective

To identify culturally grounded well-being practices among Black men in midlife and examine their associations with physiological health.

Methods

Analyzing data from the 2004–2005 Midlife in the United States (MIDUS) study, we examined, 116 open-ended responses to the question, “What do you do to make your life go well?” Network topic modeling identified six topics: (1) interpersonal kindness and positive mindset; (2) caring for children; (3) practicing spirituality and faith; (4) maintaining social connections and well-being; (5) avoiding stress; and (6) meaningful work and daily activities. Topic scores, reflecting participants’ tendency to discuss these themes, predicted allostatic load and …

Dental Educators' Perceptions Of Factors Contributing To Their Well‐Being—A Qualitative Study, M. Powell, Y. Howell, S. Anishchuk, S. Bhatia

Peninsula Dental School

BackgroundStress levels within academic institutions are high and have continued to rise over recent decades. This can have a detrimental impact on the well-being of dental educators and puts them at a risk of burnout. It is vital to explore the factors that affect the well-being of staff and identify solutions to inform the development of strategies for the promotion of well-being.MethodsParticipants attending the ADEE annual conference were invited to participate in a qualitative study using focus group discussions to explore this topic. Prompts for the four focus group discussions were identified from quantitative data collected in an earlier study …

Message From The President, Georgia Southern University

Messages from the President

No abstract provided.

Midweek Memo, Georgia Southern University

Midweek Memo

• Applaud 
• Remember 
• Share 
• Experience 
• Around the Nest

Perioperative Care Of A Child With Miller-Dieker Syndrome., Samantha A Currier, Lance M Relland, Joseph D Tobias

Ambulatory and Primary Care Articles

Miller-Dieker syndrome (MDS), also known as Miller-Dieker lissencephaly syndrome or chromosome 17p13.3 deletion syndrome, is a rare chromosomal disorder (microdeletion syndrome) characterized by lissencephaly, altered facial features, and neurologic disability. Classic phenotypic findings include a prominent forehead, micrognathia, and a short nose. Children with MDS are often born with associated end-organ involvement including congenital heart disease as well as motor and neurologic impairments including seizures. Progressive central nervous system involvement frequently leads to upper airway and swallowing dysfunction with recurrent bouts of aspiration, pneumonia, and respiratory failure. We present a 3-year-old child with MDS who presented for anesthetic care for …

Defining The Dynamic Role Of Belongingness In Alcohol Use Disorder Treatment, Brendan E. Walsh

USF Tampa Graduate Theses and Dissertations

Drinking is intertwined with social processes, including social support and group belongingness. Although drinking can transiently enhance social functioning, escalating to heavy use can be detrimental to it. It is well-known that excessive drinking and social dysfunction exacerbate each other over time, and it follows that social support and belonging are key mechanisms of addiction recovery. Yet, less is known about how changes in belongingness throughout treatment dynamically affect drinking outcomes, and even less is known about how drinking outcomes and other social processes (e.g., therapeutic alliance, interpersonal drinking consequences) dynamically influence belongingness. The current project (N = 210) studied …

The Influence Of Social Media Messaging On Human Papillomavirus Vaccine Attitudes And Confidence Among Adolescent Males: Group Discussion Study, Neha Trivedi, Rachel Van Vleet, Czesia Eid, Amelia Burke-Garcia, Amy Leader

Department of Medical Oncology Faculty Papers

BACKGROUND: Despite the human papillomavirus (HPV) vaccine being available to males for the past 12 years, adolescent males continue to lag in HPV vaccine uptake due to a variety of factors. With the ubiquitous nature of social media use among this population, further research is needed to improve HPV vaccine confidence among young adolescent males using these platforms.

OBJECTIVE: Using the Elaboration Likelihood Model (ELM), this study sought to better understand knowledge, attitudes, and beliefs about HPV and HPV vaccination among male adolescents aged 14-17 years and examine how social media messaging influences vaccine perceptions and explore the characteristics of …

Carbon Accounting And Beyond: An Evidence-Based Life Cycle Assessment Of The Environmental Impacts Of Data Center It Equipment, Meghann Smith, Manveer Mann, Pankaj Lal

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Data centers are essential to modern infrastructure, but are significant contributors to greenhouse gas (GHG) and related environmental challenges. Despite energy efficiency improvements, rising electricity demands driven by technologies like AI pose challenges to sustaining low-emission sector growth. Regulatory requirements mandate data center operators to report electricity use and emissions, yet current methods, particularly pertaining to indirect sources, remain insufficient. This study explores how life cycle assessment (LCA)-based estimates of data center IT equipment impacts compared with commonly used corporate GHG accounting methods: average-data and spend-based. Environmental impacts were modeled at both grouped and granular levels to support enterprise-wide reporting …

The President's Column, Laura Slavin

The Southeastern Librarian

SELA President Laura Slavin's column for the Spring 2026 issue of the Southeastern Librarian

Character Demographic Assessment In An Academic Library's Graphic Novel Collection: Implications For Collection Development, Bridgette L. Whitt

The Southeastern Librarian

This article presents an analysis of the main character demographics across a graphic novel collection housed at the Paul Meek Library, University of Tennessee at Martin. The study evaluates the presence of specific identified character traits such as race, ethnicity, ability, emotional or psychological themes, and the settings of the 451 evaluated titles. The assessment also evaluates the genre distribution of fiction, nonfiction, and biographical content and how often the novels were set outside of the United States. The goal of this study was to better understand the narrative scope and representation within the graphic novel collection, with a focus …

From Print To Pixels: Preserving Alabama’S Historic Newspapers Through Digitization, David Ferrara, Melissa Young

The Southeastern Librarian

This article presents a case study of the Alabama Digital Newspaper Project (ALDNP), a grant-funded initiative to digitize Alabama’s historic newspapers. It outlines the establishment and history of ALDNP, including its accomplishments, and the challenges faced and overcome by University of Alabama Libraries Special Collections (UALSC) staff. This case study details ALDNP’s workflows, including title selection, metadata creation, technical standards, and microfilm digitization. This article also highlights outreach efforts, including collaborations with regional archives, student workers, and community educators. In addition to providing details on the accomplishments of ALDNP, it also outlines potential areas for growth and expansion. Detailing a …

Cultural Humility In Libraries: A Call To Action And Strategies For Success, Megan Callaghan

The Southeastern Librarian

Authors: Shannon D. Jones & Beverly Murphy, eds.

Lanham: Rowman & Littlefield, 2024

ISBN: 9781538162156

196 pp. $39.95 (Pbk)

Government Documents For All, Tim Dodge

The Southeastern Librarian

The Government Documents for All column for the Spring 2026 issue of The Southeastern Librarian

Proper Imposters: Four Novellas, Allison Faix

The Southeastern Librarian

Authors: Chaya Bhuvaneswar, Mauricio Montiel Figueiras, Jason Ockert, & Jeff Parker

Pensacola: Panhandler Books, distributed by University of Florida Press, 2025

ISBN: 9780991640485

206 pp. $24.95 (Pbk)

Southeastern Librarian 74(1) Spring 2026 (Full Issue), John H. Barnett

The Southeastern Librarian

Complete issue of the Southeastern Librarian, Volume 74 Number 1, Spring 2026

Editor's Notes, John H. Barnett

The Southeastern Librarian

The Southeastern Librarian editor's column for the Spring 2026 issue

Mob Rule In The Ozarks: The Missouri And North Arkansas Railroad Strike, 1921-1923, Kristine Stilwell

The Southeastern Librarian

Author: Kenneth C. Barnes

Fayetteville: University of Arkansas Press, 2025

ISBN: 9781682262627

304 pp., $24.95 (Pbk)