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School Of Law Commencement: May 4, 2024, University Of North Dakota

UND Commencement Programs

UND School of Law Commencement program from May 4, 2024.

Mental Health Among Collegiate Athletes, Stella Elise Fairbanks

Honors Thesis

Mental health has become increasingly more linked with athletics, especially collegiate athletics. There has been an increase in public acknowledgment of the presence of mental health in sports, specifically, more athletes are speaking about their mental health struggles as well as more research is being conducted in order to gain a greater understanding of the relationship between mental health and athletics. This literature review discusses athletes’ personal experiences of their mental health struggles, the presence of stigma associated with mental health and athletics, and the results of the recent NCAA, National Collegiate Athletic Association, research. This thesis aims to uncover …

Understanding The Importance Of Dreissenid Mussel Mitigation In South Dakota, Allison P. Gross

Honors Thesis

Since 2014, dreissenid mussels have been established in South Dakota, spreading throughout the state. These invasive mussels can be vastly detrimental to an environment and completely disrupt the balance of natural systems they invade. In South Dakota, a state that relies heavily on land and resource use for some of the state’s major economic drivers, such as agriculture, hydropower, and tourism, the issue could be incredibly harmful if left uncontrolled. The mussel’s impacts range from increasing rash-causing bacteria in lakes and rivers to damaging critical infrastructure within dams. To understand the importance of the issue further, this paper explores the …

Prioritizing Belonging For Pk-12 Families On Financial Assistance In Private Schools, Deana Clapp

Doctorate in Education

This dissertation examined the experiences of 10 families of students in PK-12 private schools leveraging financial assistance (FA) to afford tuition and seven school FA staff who worked with families. Current literature is prominent in higher education but scant in the PK-12 milieu. Moreover, qualitative studies examining student experience in higher education have only recently begun unfolding. Drawing from a qualitative phenomenological study with an interpretivist, critical approach, this study discloses school belonging and marginalization sentiments vis a vis the power of school practices and policies to shape student and family experience. This study shares the vulnerability of private PK-12 …

Promoting Wakefulness To Increase Occupational Engagement In Military Service Members Experiencing Insomnia Following Mtbi, Leah N. Myers

Occupational Therapy Capstone Presentations

Sustaining a traumatic brain injury of any severity is associated with an extremely high prevalence of insomnia. Military service members, being exposed to hazardous equipment and conditions, are one of the most likely populations to sustain sleep concerns following TBI. This student capstone project aimed to support military service members experiencing sleep disturbances due to TBI through direct advanced clinical skill attainment, Light Therapy program development, and by initiating research and clinic resource creation relating to shift work and sleep. To target this population, the project was completed at the Fort Carson Intrepid Spirit Center in Colorado where outpatient concussion …

Occupational Therapy’S Role As A Member Of An Interdisciplinary Feeding Team For Children With Sensory Processing Differences, Emily G. Bruinsma

Occupational Therapy Capstone Presentations

Considering the high prevalence of pediatric feeding disorders and the increased need for occupational therapists trained to work with children with feeding challenges, this project sought to provide a better understanding of the key components of a feeding therapy program. These components include caregiver involvement, use of an interdisciplinary team, interventions aimed at sensory integration, and the inclusion of family-centered and motivating interventions. The Sensory Integration theory was used to guide this project by providing an understanding of the various ways individuals can receive and respond to sensory information. There were three primary goals for this capstone project, including developing …

An Eye-Opening Capstone: A New Perspective On Occupation-Based Treatments For Neurologic-Based Visual Deficits, Katlyn J. Knakmuhs

Occupational Therapy Capstone Presentations

The purpose of this 14-week capstone experience was to gain hands on in depth clinical experience working with individuals post neurologic injury, specifically post-concussion, who were experiencing a visual perceptual deficit. Additionally, the focus of this capstone was to implement occupation-based skills and activities into therapy sessions for individuals experiencing those visual perceptual deficits post-concussion. This capstone experience took place at the Sanford Outpatient Rehabilitation Clinic in Sioux Falls, South Dakota and was completed under the supervision of a licensed occupational therapist who is a certified brain injury specialist. Eight individuals post-concussion with visual perceptual deficits who were patients of …

Implementing The Copm To Create Occupation-Based Interventions In Outpatient Adult Rehabilitation, Kelcee A. Bacon

Occupational Therapy Capstone Presentations

Worldwide, people continue to live longer, with the number of people over the age of 60 predicted to double by 2050; many of those people also have chronic diseases that could benefit from rehabilitation services. Outpatient rehabilitative services, including occupational therapy, have increased occupational performance, strength, mobility, and coordination for those diagnosed with musculoskeletal or neurological conditions. This capstone focused on three components: 1) in-depth clinical practice using occupation-based assessments and interventions with the adult population, 2) understanding the administrative roles of private practice therapists, and 3) creating educational materials to increase knowledge and skills surrounding outpatient occupational therapy for …

Healing Horses: An Occupational Therapy Approach In An Equine Environment, Ashlyn Renee Yoder

Occupational Therapy Capstone Presentations

Aim: This project focused on the development of advanced clinical skills of OT-based hippotherapy in a pediatric setting and program development of the Genesis Therapeutic Riding Center. Information was gathered from primary and secondary sources to promote student skill acquisition, client goal progress, and parent-caregiver education of at-home interventions.

Objective: Goals focused on gaining knowledge and competencies of OT-based hippotherapy, key clinical information, and interdisciplinary roles. The purpose of this project was to highlight the impact of staff responsibilities and OT-based hippotherapy on physical and cognitive deficits.

Method: OT hippotherapy session observation and facilitation, extensive literature review, and multidisciplinary interviews …

Cosmetic Formulations From Natural Sources: Safety Considerations And Legislative Frameworks In The European Union: Safety Considerations And Legislative Frameworks In The European Union, Maame Ekua Manful, Lubna Ahmed, Catherine Barry-Ryan

Research Outputs: 2025-Present

Consumer preferences, safety, and sustainability aspects of conventional cosmetic ingredients have contributed to an increase in the demand for natural cosmetic ingredients and products. Naturally derived active cosmetic agents and excipients may come into contact with various naturally occurring and synthetic contaminants throughout the supply chain, and substantiating their safety is essential. This review examines the safety and legislative requirements applicable to natural cosmetic ingredients in the European Union (EU). Cosmetic safety requirements include technical data based on the ingredient profile, presence of hazards and the risks associated with the intended conditions of use. The hazard analysis includes screening for …

Incorporating A High Fidelity Transgender Simulation Into Undergraduate Nursing Curriculum, Kacee Child, Jenniepearl Spencer

Doctor of Nursing Practice Projects: College of Nursing

Purpose

The purpose of this study was to evaluate the knowledge and attitudes of nursing students participating in a high-fidelity transgender patient simulation. The aims were to increase student knowledge and confidence to improve communication and provide more inclusive and equitable care.

Healthcare providers are not adequately prepared to manage the unique health needs of the lesbian, gay, bisexual, transgender, and queer (LGBTQ) community. Nurses are ideally positioned to address gaps in LGBTQ healthcare by providing culturally competent care. Yet, LGBTQ health education is lacking in most undergraduate nursing school curriculums.

Methods

62 undergraduate nursing students participated in a post-surgical …

Ruby Lee Wilson Mitchell

African American Funeral Programs

No abstract provided.

Improving Collection Of Second Blood Pressure For Patients In Primary Care Who Present With An Elevated Reading, Jordan Sieh, Elizabeth Sundberg, Tania Arreguin

Doctor of Nursing Practice Projects: College of Nursing

Purpose: Early diagnosis of hypertension is critical to prevent complications such as renal and cardiovascular diseases. Many healthcare facilities do not have a blood pressure training program educating appropriate staff on importance of accurate blood pressure readings and techniques. The purpose of this project is to improve the number of patients with elevated blood pressure reading at the OneWorld Quick Sick Clinic.

Methods: Health aides/Health Assistants/Medical assistants at OneWorld Quick Sick will receive blood pressure training to review proper techniques. During this training they will also be educated on appropriate follow-up blood pressure readings and a new technique to document …

Identification Of Mitotic Phosphatases And Cyclin K As Novel Molecular Targets In Pancreatic Cancer, Yi Xiao

Theses & Dissertations

Pancreatic cancer is a highly lethal disease worldwide. Given the limited effectiveness of current regimens in restricting tumor progression, it is imperative that potential molecular targets be identified to offer valuable insights into alternative therapeutics. By using a phosphate-binding tag (Phos-tag) technique, previous studies have identified several Hippo pathway-related proteins and kinases required for cancer growth or paclitaxel resistance. This work has screened various phosphatases and cyclins/cyclin-dependent kinases (CDKs) as potential cancer targets, but specifically focuses on characterizing the roles of carboxy-terminal domain small phosphatase like 2 (CTDSPL2), apoptosis-stimulating protein of p53-2 (ASPP2), and Cyclin K in pancreatic cancer.

CTDSPL2 …

Therapeutic Effects Of Bet Protein Inhibition In B-Cell Malignancies And Beyond, Audrey L. Smith

Theses & Dissertations

Chronic lymphocytic leukemia (CLL) develops through a combination of intrinsic genetic defects, constitutively active survival/proliferation signaling pathways, and complex microenvironment interactions. Redundant tumor microenvironment (TME) immuno-suppressive mechanisms and epigenetic maintenance of terminal T-cell dysfunction also greatly hinder anti-tumor T-cell responses in CLL. Small-molecule agents targeting the B-cell receptor (BCR) pathway and anti-apoptotic proteins alone or in combination with chemo-immunotherapy have revolutionized the management of CLL, yet there is still a significant need for novel therapeutic strategies to yield durable tumor elimination. Bromodomain and extra-terminal domain (BET) proteins are epigenetic readers that bind to acetyl-lysine residues on histones to regulate gene …

Normal And Varied Morphological Structure Of The Fossa Ovalis And Its Clinical Relevance, Christian G. Valverde

Theses & Dissertations

Congenital heart defects are atop the list of the most common type of birth defects in modern obstetrics. According to the Center for Disease Control and Prevention, nearly 40,000 births each year are diagnosed with a congenital heart defect, composing an annual rate of 1%. Of those 40,000 births, roughly 1 in 4 are severe enough to require surgical intervention. Acknowledging that heart disease has been the leading cause of mortality for the past several decades, the former can certainly have additive effects toward this trend. There are several different etiologies and forms of heart defects that are often found …

Identifying The Molecular Determinants Of Lung Metastatic Adaptation In Prostate Cancer, Grace M. Waldron

Theses & Dissertations

Prostate cancer (PC) stands as the primary diagnosed cancer in men in the US at approximately 299,010 cases in 2024 and ranks second globally, posing a significant public health challenge. Clinical presentations vary widely, from indolent to aggressive forms, necessitating stage-specific treatment regimens. Understanding its metastatic nature is critical due to the impact of cancer cell dissemination on disease morbidity, with bone and visceral organs serving as key sites of metastasis. Despite bone metastasis being the most common site for metastasis, visceral metastases at sites such as the liver and lungs correlate with poorer survival, emphasizing the role of microenvironmental …

The Relationship Between Amygdala And Orbitofrontal Cortex Volume In The Context Of Oppositional Defiant Disorder, Rahul Alla

Honors Scholar Theses

Disobedient and rebellious attitude in children is on the rise and this type of behavior is categorized as Oppositional Defiant Disorder (ODD). ODD in children can be identified as a persistent pattern of angry or irritable mood, argumentative or defiant behavior or vindictiveness toward others according to the Diagnostic and Statistical Manual (DSM-5, Fifth Edition) of Mental Disorders.1 Children with ODD typically have difficulty regulating and processing their emotions. Issues with regulating emotions is defined as the process by which individuals “influence which emotions they have, when they have them, and how they experience and express them”.2 Dysregulation of emotions …

Geraldine Boyd

African American Funeral Programs

Geraldine_Boyd.pdf - Funeral program for Geraldine Mikell Boyd

Crowdfunding And Intellectual Property, Mirit Eyal-Cohen

Colorado Technology Law Journal

No abstract provided.

Investigating The Impact Of Secondary Activation Time On The Adsorption Properties Of Activated Biochar For Arsenic Removal From Wastewater, Achyuth Bharadwaj Rayarao

Graduate Theses and Dissertations (2019 - present)

Biochar, a naturally occurring and renewable carbon material, becomes porous through activation. Activated biochar is an ideal candidate for use as an adsorbent. The objective of this study is to investigate whether activated biochar derived from Colorado soft pine serves as a better adsorbent and demonstrates enhanced adsorption capabilities after undergoing secondary physical activation at various activation times. The effect of secondary action time on physical adsorption properties drawn from the analysis of isotherm plots, surface areas and pore size patterns were examined by using a physisorption analyzer. Chemical structures were identified using both ultimate and proximate analyses, while porosity …

Heavy Metals In Afforested Mangrove Sediment From The World's Largest Delta: Distributional Mapping, Contamination Status, Risk Assessment And Source Tracing, Md Saifur Rahman, Moshiur Rahman, Yeasmin N Jolly, Md Kamal Hossain, Sanjida Afrin Semme, Bilal Ahamad Paray, Takaomi Arai, Jimmy Yu, M Belal Hossain

Faculty, Staff and Student Publications

This study aims to assess seasonal and spatial variations, contamination status, ecological risks, and metal sources (Ni, Pb, Cr, Cu, Mn, and Zn) in human-afforested mangrove sediments in a deltaic region. Five sampling locations were sampled during dry and wet seasons. Heavy metal concentrations followed the order: Mn > Zn > Ni > Cr > Cu > Pb. Metal loads, except Cu and Pb, were higher during the dry season, aligning with national and international recommendations. Sediment quality guidelines, contamination factor, geoaccumulation index, enrichment factors, and pollution load index indicated uncontaminated sediment in both seasons. Potential ecological risk assessment showed low risk conditions in all …

Understanding The Accounting Of Agilysys' Current Business Model And Other Economic Activities, Brick Gore

Honors Theses

Agilysys operates out of the hospitality software industry and has seen a recent incline in volume due to the convenience and advancements of technology. They point of sale systems make it simple to conduct transactions; therefore, while the hospitality companies were negatively impacted during Covid-19, they were still able to sustain. Agilysys is posed a threat from operational risks, such as global climate change and rising interest rates as their products are many times located in luxurious environments; however, their current business model allows them to reduce this risk. From an auditor’s perspective, there are riskier accounts, and without a …

Genetic Drivers And Tumor Milieu Analysis In Mantle Cell Lymphoma, Sunandini Sharma

Theses & Dissertations

Mantle Cell Lymphoma (MCL) is a B-cell lymphoma characterized by t(11;14) leading to CyclinD1 (CCND1) overexpression with highly variable clinical response. Although the tumor intrinsic mechanisms have been fairly studied, the role of the tumor microenvironment (TME) in survival and therapeutic responses is marginally examined. Herein, we integrated high-throughput genomics and characterized TME using a highly multiplexed, spatially resolved, single-cell digital pathology approach termed imaging mass cytometry (IMC) to delineate the tumor-immune landscape. We identified eight MCL genomic subtypes with distinct signatures and prognoses. Subsets C2, C5, and C6 had poorer outcomes with a 5-year overall survival (OS) of 33-50% …

Pharmacodynamic Effects Of Zsj-0228 On Complement Protein Deposition In The Kidneys Of Focal Segmental Glomerulosclerosis-Afflicted Mice., Braeden Pinkerton

Theses & Dissertations

Chronic inflammation, when left untreated, may result in significant morbidity and in severe cases, mortality. While glucocorticoids (GCs) are still being extensively used clinically as a class of very potent anti-inflammatory agents, they are also notorious for diverse adverse side effects. To mitigate these side effects, we have developed a polyethylene glycol (PEG)-based prodrug (ZSJ-0228) of dexamethasone (Dex). When tested on rodent models of Lupus Nephritis and Focal Segmental Glomerulosclerosis (FSGS), ZSJ-0228 was found to provide potent and sustained therapeutic efficacy without any detectable typical GC-associated side effects. Given ZSJ-0228’s transient renal exposure after systemic administration, it is yet to …

Gene Co-Expression And Machine Learning Approaches To Compare Sars-Cov-2 Infected Tissues In Humans, Sahil Sethi

Theses & Dissertations

The global outbreak of COVID-19, triggered by the novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has spurred an urgent need for a deeper comprehension of the molecular mechanisms involved in the host-virus interactions. Despite advancements in transcriptomic technology and computational resources, limited attention has been given to the holistic integration of molecular and clinical data to characterize the genotype/phenotype aspects of the disease.

This study analyzes gene expression patterns in various tissues, including the lung, nasal, blood, and placenta, in patients with COVID-19 to identify differentially regulated genes and pathways. We also evaluated organ-specific gene co-expression patterns that …

Cardiovascular Disease Risk Reduction Program For Hispanics In The Us Midwest: A Culturally Adapted Intervention, Armando De Alba

Theses & Dissertations

Cardiovascular disease (CVD) represents the second leading cause of death in Nebraska (NE), accounting for approximately one in every five deaths. In the state, there are marked ethnic and rural-urban disparities in the prevalence of chronic diseases and resultant deaths. For instance, while the rates in NE of coronary heart disease and myocardial infarction between 2001 and 2010 decreased among non-Hispanic Whites, the rates for Hispanics almost tripled. There is little evidence of CVD risk factor reduction strategies being implemented in Midwestern areas and Hispanic populations.

One promising approach for reducing CVD risk involves health education and lifestyle modification programs …

Major Injuries Sustained In Towable Watersports, Elijah J. Klein

Honors Thesis

Towable watersports are activities where a participant is being pulled by a motorized watercraft while wearing or holding onto a floating device. Watersports come with many known risks such as drowning, whiplash, and fatigue; however, other injuries are often overlooked or misunderstood. With this thesis, I aimed to explore injury records pertaining to towable watersports and attempted to identify prevalent injury trends in wakeboarding, waterskiing, and water tubing. Using the National Electronic Injury Survey System (NEISS), a public database with yearly injury records, I compiled information related to the relevant sports from 2013 to 2022. Included with the data is …

Diet-Omics In The Study Of Urban And Rural Crohn Disease Evolution (Source) Cohort, Tzipi Braun, Rui Feng, Amnon Amir, Nina Levhar, Hila Shacham, Ren Mao, Rotem Hadar, Itamar Toren, Yadid Algavi, Kathleen Abu-Saad, Shuoyu Zhuo, Gilat Efroni, Alona Malik, Orit Picard, Miri Yavzori, Bella Agranovich, Ta-Chiang Liu, Thaddeus S Stappenbeck, Lee Denson, Ofra Kalter-Leibovici, Eyal Gottlieb, Elhanan Borenstein, Eran Elinav, Minhu Chen, Shomron Ben-Horin, Yael Haberman

Faculty, Staff and Student Publications

Crohn disease (CD) burden has increased with globalization/urbanization, and the rapid rise is attributed to environmental changes rather than genetic drift. The Study Of Urban and Rural CD Evolution (SOURCE, n = 380) has considered diet-omics domains simultaneously to detect complex interactions and identify potential beneficial and pathogenic factors linked with rural-urban transition and CD. We characterize exposures, diet, ileal transcriptomics, metabolomics, and microbiome in newly diagnosed CD patients and controls in rural and urban China and Israel. We show that time spent by rural residents in urban environments is linked with changes in gut microbial composition and metabolomics, which …

Assessment Of In-Vitro And In-Vivo Pre-Clinical Pharmacokinetics Of Epz015666; A Novel Small Molecule For Medulloblastoma Treatment, Pratiksha U. Kshirsagar

Theses & Dissertations

Group 3 medulloblastoma (MB) has the worst prognosis of the MB subgroups associated with elevated MYC expression and a 5-year survival rate of

Quantitation of EPZ was performed on a Shimadzu LC-MS/MS system utilizing electrospray ionization operated in positive mode. The validated assay was linear from 0.2 to 500 ng/mL. Metabolic stability studies demonstrated slow intrinsic clearance of EPZ in mouse and human liver microsomes, suggesting no CYP-mediated metabolism. Additionally, EPZ exhibited low binding affinity to plasma and brain proteins and high apparent permeability across artificial membranes, indicating efficient membrane penetration. Drug transporter studies identified EPZ as a substrate of …