Digital Commons Network^™

A Mind-Body Intervention To Improve Physical Activity For Patients With Chronic Hip-Related Pain: Protocol For A Mixed Methods Study., Kate N Jochimsen, Kristin R Archer, Robin A Pollini, Robert A Parker, Nomin Enkhtsetseg, Cale A Jacobs, Ana Maria Vranceanu

Psychiatry Faculty Publications

BACKGROUND: Pain and dysfunction persist for most patients following hip-related pain treatment. Additionally, individuals with hip-related pain are typically less physically active than individuals without hip pain, despite evidence that regular physical activity reduces chronic musculoskeletal pain. Poor psychological health is common in patients with hip-related pain and further reinforces low physical activity. Mind-body interventions can improve psychological health and activity levels but have yet to be integrated to provide comprehensive, psychologically informed care for patients with hip-related pain. Thus, we are using the NCCIH intervention development framework to develop Helping Improve PSychological Health (HIPS), a novel, multimodal mind-body intervention …

Graduates: Stay Focused, Remember Ole Miss And Find Happiness Within, Emily Howorth

University of Mississippi News

When the Class of 2024 graduates Saturday (May 11), they'll complete one journey and embark on the next. Just like those who came before them, these new graduates are ready to grow the legacies they've started at the University of Mississippi.

Utilization Of Negative Pressure Wound Therapy And Split Thickness Skin Grafts In The Context Of Complex Skin Closure Via Secondary Intention: A Protocol Approach, Jihan Toma, Eric Li, Randy Semma, Michele Bertelle-Semma, Asif Khan

Posters

Patients with complex, chronic foot wounds or ulcerations are at risk for major amputations. In this quality improvement (QI) initiative, we present an implemented protocol for patients with foot ulcerations and attempt to heal them using a combination of wound vac therapy and split thickness skin grafting. These patients have a history of either diabetes and/or neuropathy that makes wound healing more difficult than an otherwise healthy individual.

Diabetic Limb Salvage: Chopart Amputation, Jesse Miller, Randy Semma

Posters

Diabetic limb salvage is the act of saving a limb, even with decreased function after infection.

It is the difficult choice of the surgeon/patient to decide to proceed with salvage versus amputation proximally.

Case Report Of Bullous Diabeticorum: A Self-Limiting Condition With Potentially Devastating Consequences, Taylor Allison, Randy Semma

Posters

Bullous diabeticorum (BD) is a skin manifestation of patients with diabetes mellitus with an incidence of about 0.16% per year (Larsen et al) although the condition is believed to be widely underdiagnosed. The blistering disease favors acral regions of the body including the feet. There are no accepted diagnostic tests, and histopathology results are often inconclusive which makes BD a clinical diagnosis of exclusion. It is often self-limiting and resolves in a few weeks without residual sequelae. However, it may present with a secondary bacterial infection which can put patients at risk for soft tissue infections and osteomyelitis requiring more …

Revisional Arthrodesis Of Tarsometatarsal (Lisfranc) Complex Injury Secondary To Non-Union, Lei Wilson, Randy Semma

Posters

The tarsometatarsal joint and its components provide structural support for the foot. Notably the Lisfranc ligament is a fundamental stabilizer for the midfoot. Injuries to this component are complex and can be debilitating. These injuries require surgical intervention when significant displacement resulting in instability is involved.

Following success of several previous repairs of Lisfranc fractures and dislocations, a treatment algorithm has been proposed. This case report demonstrates the success of the algorithm which has allowed the surgeon to perform reduction and repair in a reproducible, step-wise manner with minimal difficulty to ensure successional revisional arthrodesis of a non-union

Cohort Study Using A Survey To Evaluate The Effects Of Sleep On Hba1c Levels And Foot Pathology In Patients Seen In The Podiatry Clinic, Carmen Johnson, Eric Li, Jihan Toma, Marshall G. Solomon

Posters

We investigate the impacts of sleep issues on patients in the podiatry clinic by comparing HbA1c, sleep, and foot pathology. Diabetic foot pathology of peripheral arterial disease, peripheral neuropathy, lower extremity ulcerations, and a history of lower extremity amputation all increase the patient's risk of future amputation. Once a patient has an amputation of the lower extremity the five-year mortality rates are 40-70%. So, limb salvage not only improves the quality of life, but also increases the life expectancy for patients. Through a survey and chart review, we are investigating possible impacts of sleep issues on diabetic patients seen in …

Septic First Metatarsophalangeal Joint Arthrodesis With Alternative Mini-Rail Fixation, Brenna Barker, Morgan Gascoyne, Randy Semma

Posters

For non-infection cases, first metatarsal phalangeal joint arthrodesis is a definitive procedure for painful, arthritic joints.

Standard fixation methods include screws, plates, staples, or a combination of the three.

For complex septic joint cases, an alternative method of fixation is needed to reduce the risk of infection retention.

The Diagnosis Of Polyarteritis Nodosa In The Setting Of Lower Extremity Lesions: A Case Report, Eric Li, Jihan Toma, George Gopoian

Posters

Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affecting medium-sized arteries, involving multiple organs, with the most frequently affected tissues being skin and peripheral nerves (1). The distinct pearl neckless pattern led to the naming of this condition (2). Cutaneous polyarteritis nodosa (CPAN) is a variant of PAN confined to the skin, muscles and peripheral nerves in the absence of any systemic involvement (1). This rare form of systemic necrotizing vasculitis is limited to the medium-sized arteries of the skin and has a more favorable prognosis (1). PAN is also linked to Hepatitis B(2). The current diagnostic criteria for CPAN …

Repair Of Achilles Tendon Re-Rupture With Fhl Transfer: A Case Study, Taylor Allison, Joshua Kazdan

Posters

The Achilles tendon consists of the soleus muscle and two heads of the gastrocnemius muscle. Loss of its function can result in loss of plantarflexion strength, which can impact activities of daily living. In a study by Scheller et al, Achilles tendon ruptures were missed on initial evaluation on 25% of their patients. Other studies have reported a similar incidence of misdiagnoses. Patients may also delay treatment due to decreased pain after the initial injury. Ruptures diagnosed 4 weeks from injury are often considered chronic, and many of these patients benefit from surgical repair. A flexor hallucis longus (FHL) transfer …

Antibiotics Vs Surgical Resection In Foot And Ankle Osteomyelitis, Travis Rich, Marshall G. Solomon

Posters

Osteomyelitis, a serious bone infection, is particularly challenging in diabetic patients due to poor vascularization and impaired immune response.1 Timely and effective treatment is essential to prevent severe complications, including limb loss or even death.2 This study aims to evaluate the likelihood of surgical excision or amputation versus antibiotic treatment alone in diabetic patients with bone biopsyconfirmed acute osteomyelitis of the lower extremity.

Relative Influence Of Sea State And Mean, Turbulent, And Heterogenous Refractivity On X-Band Propagation, Douglas M. Pastore, Erin E. Hackett

Marine Science

In predicting electromagnetic wave propagation within the marine atmospheric surface layer, it is common to assume steady homogenous conditions. However, discrepancies between predicted and measured propagation remain, which could be due in-part to turbulent fluctuations of the refractive index, spatially heterogenous evaporative ducting environments, and mischaracterization of the rough ocean bottom boundary. To better understand the relative importance of these contributors, this study explores the sensitivity of X-band propagation to parameters describing sea-state conditions and refractive environments, including turbulent fluctuations and spatially heterogenous conditions. This study employs the extended Fourier Amplitude Sensitivity Test to compute sensitivity indices that evaluate the …

Eve Sexton, Eve Sexton

Professional Practices (ART 399)

In my personal landscape art, there is a focus on nature, family and nostalgia. Combining those elements usually allows thoughts to percolate of times in life where people feel most akin with nature. I feel there is peacefulness in nature, as well as the fact that it is something that has been around for eons, provokes thoughts of mankind’s place and progression in the world. There is an order and a system that things just instinctively follow in nature, life and death is so common and unavoided. Things grow, they die back, they come up again when the time is …

Software Development And Market Research Process Of Plasma Software Distribution, Connor Moore

Honors College Theses

When trying to find the right software for scientific research, one may have to comb through the internet to acquire a suitable tool. Much of the scientific software online is in mostly unknown web pages where the only way to find the software is to already know about it, be told about it, or find the software by pure chance. Even worse, with few verification systems in place they may try a new program only for it to turn out to be malware. The search for the right software takes time away from the scientists, slowing the overall pace of …

Nontraumatic Emergencies Of The Head And Neck, Adam Bernardi

Aurora GME

No abstract provided.

Undifferentiated Pleomorphic Sarcoma Of The Face, Erin Brown, Cheyenne Rahimi, Neel D. Gupta, Jagan D. Gupta, Triet M. Do, Mae Igi, Enrique Palacios

School of Medicine Faculty Publications

No abstract provided.

Metabarcoding The Mycobiome: An Analysis Of The Gut Mycobiome Of Babies, Daniel B. Colon, Jeremy Seto

Publications and Research

The human gut mycobiome (the fungus that lives in our gut) has been correlated with overall health and disease in humans. There are several factors that affect the human gut mycobiome including delivery method during birth (vaginal vs. c-section) and the presence or absence of antibiotics at birth. The mycobiome of 140 infants aged newborn to 18 months were tested using fecal samples from 3 different time periods (meconium, 6 months, 18 months). A total of 434 fecal samples were collected. A midwife or nurse collected the meconium samples while the child’s parents collected the samples at the 6-month and …

Full Issue

The Bridge

No abstract provided.

Failed Medial Column Fusion Due To Subtalar Joint Instability, Travis Rich, Randy Semma, Michele Bertelle-Semma

Posters

CNA is a destructive complication affecting the bone and joint structure, most often in diabetics w/ longstanding peripheral neuropathy.

High incidence of major amputation associated with Charcot foot.

Kaposi Sarcoma Case Study, Mohamed Elshebiny, Marshall G. Solomon

Posters

No abstract provided.

Cd21 Stains Dendritic Networks In Tertiary Lymphoid Structure Of Transplant Renal Biopsies To Avoid Misdiagnosis Of Borderline Changes, Brandon D. Metcalf, Wei Li, Hassan Kanaan, Ping L. Zhang

Posters

Tertiary Lymphoid Structures (TLS) have been described as germinal center-like lymphoid structures composed dendritic network, mixed lymphocytes and high endothelial venules in internal organs following primary lymphoid organs (thymus and spleen) and secondary lymphoid structures (lymph nodes and native lymphoid structures along GI tract).

The TLS is mainly located at peri-glomeruli, peri-vascular areas or renal pelvis following inflammatory insults. A recent study indicates that TLS can been seen up to 19 % of protocol transplant renal biopsies (TRB) (JASN, 2022;33:186-200).

We hypothesize that CD21 staining can identify dendritic cells of TLS so that borderline changes are not over-diagnosed.

The Vagueness Of The Independent State Legislature Doctrine, Jason Marisam

Washington and Lee Law Review Online

The Independent State Legislature (ISL) Theory has been one of the hottest topics in election law, with conservative thinkers championing a strong version of the theory. In Moore v. Harper, the Supreme Court had the opportunity to turn this controversial theory into actual doctrine. The Court, though, declined to adopt a maximalist version of the theory and declined to reject it outright. Instead, it offered a vague standard that gives close to zero guidance as to where, between these two poles, the doctrine sits. Several scholars and commentators have responded to the opinion with a mix of relief, because the …

Toward An Affective-Rhetorical Approach To Biblical Interpretation, Sophie R. Beal

Yale Divinity School Theses

No abstract provided.

Mitochondria Regulate Proliferation In Adult Cardiac Myocytes, Gregory B Waypa, Kimberly A Smith, Paul T Mungai, Vincent J Dudley, Kathryn A Helmin, Benjamin D Singer, Clara Bien Peek, Joseph Bass, Lauren Nelson, Sanjiv J Shah, Gaston Ofman, J Andrew Wasserstrom, William A Muller, Alexander V Misharin, G R Scott Budinger, Hiam Abdala-Valencia, Navdeep S Chandel, Danijela Dokic, Elizabeth Bartom, Shuang Zhang, Yuki Tatekoshi, Amir Mahmoodzadeh, Hossein Ardehali, Edward B Thorp, Paul T Schumacker

Faculty, Staff and Student Publications

Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back to a fetal glycolytic phenotype would restore proliferative capacity. We deleted Uqcrfs1 (mitochondrial Rieske iron-sulfur protein, RISP) in hearts of adult mice. As RISP protein decreased, heart mitochondrial function declined, and glucose utilization increased. Simultaneously, the hearts underwent hyperplastic remodeling during which cardiomyocyte number doubled without cellular hypertrophy. Cellular energy supply was preserved, AMPK activation was absent, and mTOR activation was evident. In ischemic hearts with RISP deletion, new cardiomyocytes …

Querida Promotora, Cristina Faiver-Serna

Faculty Publications

This open letter to the promotoras de salud (community health workers) of Long Beach, California explores the multifaceted demands placed on low-wage, highly skilled health educators within the nonprofit industrial complex, and exposes the geographies of Latinx health precarity from the perspective of urban health care feminized labor. The letter also shares and celebrates the deep commitment to justice that promotoras struggle toward through their care work.

A Bioinformatic Analysis Of T-Cell Epitope Diversity In Sars-Cov-2 Variants: Association With Covid-19 Clinical Severity In The United States Population, Grace J. Kim, Jacob H. Elnaggar, Mallory Varnado, Amy K. Feehan, Darlene Tauzier, Rebecca Rose, Susanna L. Lamers, Maya Sevalia, Najah Nicholas, Elizabeth Gravois, Daniel Fort, Judy S. Crabtree, Lucio Miele

School of Graduate Studies Faculty Publications

Long-term immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires the identification of T-cell epitopes affecting host immunogenicity. In this computational study, we explored the CD8+ epitope diversity estimated in 27 of the most common HLA-A and HLA-B alleles, representing most of the United States population. Analysis of 16 SARS-CoV-2 variants [B.1, Alpha (B.1.1.7), five Delta (AY.100, AY.25, AY.3, AY.3.1, AY.44), and nine Omicron (BA.1, BA.1.1, BA.2, BA.4, BA.5, BQ.1, BQ.1.1, XBB.1, XBB.1.5)] in analyzed MHC class I alleles revealed that SARS-CoV-2 CD8+ epitope conservation was estimated at 87.6%–96.5% in spike (S), 92.5%–99.6% in membrane (M), and 94.6%–99% in …

Re: Request For Change (Rfc-Rmap-2024-001), Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

A Novel Humanized Mouse Model For Hiv And Tuberculosis Co-Infection Studies, José Alejandro Bohórquez, Sitaramaraju Adduri, Danish Ansari, John Sahana, And Additional Authors

School of Medicine Faculty Publications and Presentations

Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to be a major public health problem worldwide. The human immunodeficiency virus (HIV) is another equally important life-threatening pathogen. HIV infection decreases CD4+ T cell levels markedly increasing Mtb co-infections. An appropriate animal model for HIV/Mtb co-infection that can recapitulate the diversity of the immune response in humans during co-infection would facilitate basic and translational research in HIV/Mtb infections. Herein, we describe a novel humanized mouse model. Methods: The irradiated NSG-SGM3 mice were transplanted with human CD34+ hematopoietic stem cells, and the humanization was monitored by staining various immune cell markers …

Importance Of Intergenerational Leadership In Organizations, Kelta Tabaku Ms.

M.S. in Leadership

Abstract

This study delved into the details of leadership within intergenerational settings, spotlighting the pivotal role of effective communication and cultural comprehension. It underscores how intergenerational leadership shapes organizational dynamics, necessitating innovative methods and meticulous succession planning. The research emphasizes the imperative of acknowledging each generation's distinct contributions and the deployment of leadership training and mentorship initiatives to cultivate inclusive leadership spanning generations. This capstone research thesis aims to explore the challenges in executing effective intergenerational leadership practices in contemporary organizations, potentially uncovering issues like communication barriers, change resistance, or generational misunderstandings. The hypothesis posits that adeptly implemented intergenerational leadership …

Jonathan Wong Art 399 Portfolio, Jonathan Wong

Professional Practices (ART 399)

Jonathan Wong’s artistic journey revolves around the profound connection between emotion and expression, finding solace in the realms of illustration and film. This transformative medium serves as a vessel for encapsulating the nuances of personal mental health struggles, offering a timeless reflection of emotional states.

Central to Wong's creative exploration is a focus on mental health, exploring the complexities of the human psyche and societal influences. Through pieces like "Social Media Kills," Wong delves into the pervasive impact of technology on modern society, utilizing vivid imagery and symbolism to evoke a response from viewers. Color palettes, facial expressions, and spatial …