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Research On Identification And Selection Practice Methods Of National Critical Technologies, Yanlin Cheng, Yaling Cao, Yan Xiao, Tao Dai

Bulletin of Chinese Academy of Sciences (Chinese Version)

National critical technologies are crucial to economic prosperity, social welfare, and national security of a country or region, playing a vital role in enhancing national scientific and technological innovation capability and boosting its international competitiveness. How to identify and select national critical technologies is the prerequisite and foundation for optimizing research layouts and cultivating priority fields. Based on the understanding of the connotations and characteristics of national critical technologies, this study proposes an analytical framework for their identification and selection. Through a cross-case analysis of practices in the United States, the European Union, South Korea, and Australia, the study compares …

2025issue5content

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Practice And Enlightenment Of National Critical Technology Strategy, Jie Chen, Xiao He, Tao Dai

Bulletin of Chinese Academy of Sciences (Chinese Version)

Critical technologies have become an important factor affecting the international competition pattern, national economic and social development, and national security. In recent years, major countries such as the United States, South Korea, and Australia have implemented national critical technology strategies to systematically promote the cultivation and protection of critical technologies at the national level. Firstly, the different strategic choices made by the United States, South Korea, and Australia based on their own advantages and foundations were compared from the dimensions of strategic positioning, focus, and main measures. The United States was analyzed as a technology leading strategy, South Korea as …

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Considerations And Initiatives For Domesticating Display Manufacturing Equipment, Songlin Ma, Shijian Qin

Bulletin of Chinese Academy of Sciences (Chinese Version)

The display panel industry has evolved from CRT to OLED, with major technology-leading regions such as Japan and South Korea adopting a vertically integrated model encompassing equipment, materials, and products. This approach ensures self-sufficiency within their regional industrial chains, while each technological leap has reshaped the global industry landscape. China’s display industry started from scratch and, through a strategy of complete technology import, digestion and absorption, and independent innovation, has gradually achieved the world’s highest shipment volume. Nevertheless, it still faces the challenge of being “large but not strong”, as core equipment for display panel production lines heavily relies on …

Survey Finds 99% Of 2023 Grads Employed Or Continuing Education, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

Assessing The Benefits Of Electrification For The Mackinac Island Ferry From An Environmental And Economic Perspective, Siddharth Gopujkar, Jeremy Worm

Michigan Tech Publications

Ferry electrification has gained attention in the last decade as a potential path to reduce greenhouse gas emissions. This study, conducted by APS LABS at Michigan Technological University for the Mackinac Economic Alliance (MEA) and funded by the Michigan Economic Development Corporation (MEDC), looked at the feasibility and potential benefits of electrification of a particular vessel that is part of a ferry service from Mackinaw City, Michigan, USA, to Mackinac Island, Michigan, USA. The study included a comprehensive analysis of the feasibility of retrofitting the current configuration of the ferry into an all-electric ferry based on the availability of components …

Ri2ap: Robust And Interpretable 2d Anomaly Prediction In Assembly Pipelines, Chathurangi Shyalika, Kaushik Roy, Renjith Prasad, Fadi El Kalach, Yuxin Zi, Priya Mittal, Vignesh Narayanan, Ramy Harik, Amit Sheth

Publications

Predicting anomalies in manufacturing assembly lines is crucial for reducing time and labor costs and improving processes. For instance, in rocket assembly, premature part failures can lead to significant financial losses and labor inefficiencies. With the abundance of sensor data in the Industry 4.0 era, machine learning (ML) offers potential for early anomaly detection. However, current ML methods for anomaly prediction have limitations, with F1 measure scores of only 50% and 66% for prediction and detection, respectively. This is due to challenges like the rarity of anomalous events, scarcity of high-fidelity simulation data (actual data are expensive), and the complex …

Developing A Membrane-Proximal Cd33-Targeting Car T Cell, Ruby Freeman, Sanam Shahid, Abdul G Khan, Serena C Mathew, Sydney Souness, Erin R Burns, Jasmine S Um, Kento Tanaka, Winson Cai, Sarah Yoo, Andrew Dunbar, Young Park, Devin Mcavoy, Kinga K Hosszu, Ross L Levine, Jaap Jan Boelens, Ivo C Lorenz, Renier J Brentjens, Anthony F Daniyan

Faculty, Staff and Student Publications

BACKGROUND: CD33 is a tractable target in acute myeloid leukemia (AML) for chimeric antigen receptor (CAR) T cell therapy, but clinical success is lacking.

METHODS: We developed 3P14HLh28Z, a novel CD33-directed CD28/CD3Z-based CAR T cell derived from a high-affinity binder obtained through membrane-proximal fragment immunization in humanized mice.

RESULTS: We found that immunization exclusively with the membrane-proximal domain of CD33 is necessary for identification of membrane-proximal binders in humanized mice. Compared with clinically validated lintuzumab-based CAR T cells targeting distal CD33 epitopes, 3P14HLh28Z showed enhanced in vitro functionality as well as superior tumor control and increased overall survival in both …

Machine Learning For Intrusion Detection: A Reproducible Baseline Is All You Need, Salma A. Walli, Karam Sallam

Sustainable Machine Intelligence Journal

Ensuring Responsible AI practices is paramount in the advancement of systems founded upon machine learning (ML) principles, particularly in sensitive domains like intrusion detection within cybersecurity. A fundamental aspect of Responsible AI is reproducibility, which guarantees the reliability and transparency of research outcomes. In this paper, we address the critical challenge of establishing reproducible for intrusion detection utilizing ML techniques. Leveraging the NSL-KDD dataset and the Edge-IIoTset, we carry out extensive experiments to evaluate the efficacy of our approach. Our study prioritizes meticulous experiment design and careful implementation setups, aligning with the principles of Responsible AI. Through rigorous experimentation and …

Reaction Mechanisms Of H2s Oxidation By Naphthoquinones, Kenneth R Olson, Kasey J Clear, Tsuyoshi Takata, Yan Gao, Zhilin Ma, Ella Pfaff, Anthony Travlos, Jennifer Luu, Katherine Wilson, Zachary Joseph, Ian Kyle, Stephen M Kasko, Prentiss Jones, Jon Fukuto, Ming Xian, Gang Wu, Karl D Straub

Faculty, Staff and Student Publications

1,4-naphthoquinones (NQs) catalytically oxidize H2S to per- and polysufides and sulfoxides, reduce oxygen to superoxide and hydrogen peroxide, and can form NQ-SH adducts through Michael addition. Here, we measured oxygen consumption and used sulfur-specific fluorophores, liquid chromatography tandem mass spectrometry (LC-MS/MS), and UV-Vis spectrometry to examine H2S oxidation by NQs with various substituent groups. In general, the order of H2S oxidization was DCNQ ~ juglone > 1,4-NQ > plumbagin >DMNQ ~ 2-MNQ > menadione, although this order varied somewhat depending on the experimental conditions. DMNQ does not form adducts with GSH or cysteine (Cys), yet it readily oxidizes H2S to polysulfides and sulfoxides. …

Defeat Delirium – Yes, We Cam!, Angela Strausser Bsn, Rn, Ccrn, Tcrn, Gero-Bc, Eileen Wasson Msn, Rn, Ccrn, Tcrn, Gero-Bc

Patient Care Services / Nursing

No abstract provided.

Flexible Biosensors For Food Pathogen Detection, Sonatan Biswas, Md Shariful Islam, Fei Jia, Yunteng Cao, Yanbin Li, Changyong Cao

Biological and Agricultural Engineering Faculty Publications and Presentations

Food contamination poses a significant threat to public health, the economy, and human health worldwide, occurring at any stage of the food supply chain, from farm to fork. Efficient and effective real-time monitoring methods for the early identification and rapid detection of pathogen contamination are critical to preventing possible food safety issues. In the past decade, flexible electrochemical biosensors have rapidly expanded in the detection of foodborne pathogens, owing to their ability to function well at biological interfaces that may be soft, intrinsically curvy, irregular, or deformable. The most important features of flexible sensors are their flexibility, multifunctionality, low cost, …

Illinois State University Graduate Course Catalog, 2024-2025, Illinois State University

Course Catalogs

Illinois State University Graduate Course Catalog, 2024-2025. Effective May 20, 2024.

Illinois State University Undergraduate Course Catalog, 2024-2025, Illinois State University

Course Catalogs

Illinois State University Undergraduate Course Catalog, 2024-2025. Effective May 20, 2024.

Structural Fiber Mesh Reinforcement Of A Polymeric Heart Valve: Improving Valve Durability And Leaflet Closure Effectiveness, Peter J. Choi, Hugo Zazueta, John A. Acevedo, Philip Park

Civil Engineering Faculty Publications

Objective: Bioprosthetic valves using either porcine or bovine pericardium have been widely used for transcatheter heart valve replacements. However, producing bioprosthetic valves is not a sustainable solution. Acquiring animal tissue is often not readily available and costly and requires time-consuming modifications. Moreover, its primary tissue failure requires reoperation after roughly 15 years. The suggested replacement of porcine and bovine leaflets with biocompatible polymers appears to be an attractive alternative to bioprosthetic valves. In this study, engineered fiber-reinforced polymers were developed, which are less degenerative and offer greater hemocompatibility in relation to mechanical valves.
Methods: Polydimethylsiloxane (PDMS) polymer reduces calcification significantly …

Practical Demonstration And Novel Optimization Control For A Smart Soft Open Point To Maximize The Synergy Between The Dc Metro Line And The Lv Distribution Grid, Tamer Kamel, Mansoureh Zangiabadi, Hongzhi Dong, Zhongbei Tian, Neal Wade, Volker Pickert, Pietro Tricoli

School of Engineering, Computing and Mathematics

The steady increment in electrical loads often requires expensive and disruptive upgrading of the electrical power supply infrastructure. This can be avoided by synergizing the DC railway networks with local AC grids using soft-open points to transfer the available regenerative braking energy of the trains to the nearby local grid. Besides, a battery energy storage system is integrated into the soft-open point to match the braking events with the grid load power. So that the new developed system effectively decouples both the rail and grid networks. This paper presents a practical study for such novel rail+grid energy management strategy. A …

Infrared Phase-Change Chiral Metasurfaces With Tunable Circular Dichroism, Haotian Tang, Liliana Stan, David A. Czaplewski, Xiaodong Yang, Jie Gao

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Integrating Phase-Change Materials in Meta surfaces Has Emerged as a Powerful Strategy to Realize Optical Devices with Tunable Electromagnetic Responses. Here, Phase-Change Chiral Meta surfaces based on GST-225 Material with the Designed Trapezoid-Shaped Resonators Are Demonstrated to Achieve Tunable Circular Dichroism (CD) Responses in the Infrared Regime. the Asymmetric Trapezoid-Shaped Resonators Are Designed to Support Two Chiral Plasmonic Resonances with OppositeCDresponses for Realizing SwitchableCDbetween Negative and Positive Values using the GST Phase Change from Amorphous to Crystalline. the Electromagnetic Field Distributions of the Chiral Plasmonic Resonant Modes Are Analyzed to Understand the Chiroptical Responses of the Meta surface. Furthermore, the …

The Role Of E-Participation, Human Capital, And Corruption-Free On Environmental Performance, Mohammad I. Merhi, Punit Ahluwalia

Information Systems Faculty Publications

There are many concerns at the global level about environmental performance. The United Nations has created a framework for measuring national development goals that enable environmental sustainability. This paper examines the relationships between technological and social factors as enablers of environmental performance and draws from technological determinism and human agency paradigms. It fills an important gap in the literature by empirically examining the hypothesized relationships. The specific examined factors are online service (maturity and quality), IT infrastructure, e-participation, corruption-free, and human capital. Environmental performance is the dependent variable. These factors are relevant to ten of the seventeen goals that the …

Living On The Outskirts Of Things: Women And Nonbinary People Of Color With Cognitive Disabilities Describe Their Employment Experiences, Laura Spura Rodriguez

Dissertations and Theses

This study examines the experiences of discrimination and the strategies used to navigate employment for women of color and nonbinary people of color (POC) with cognitive disabilities (CD) through their own narratives. Using Dis/ability Critical Race Theory and an interpretive description methodology, this study engaged 10 women of color and/or nonbinary POC with CD in semi-structured interviews in order to answer the following research questions: 1) What stories do women of color and nonbinary POC with CD tell about their experiences seeking employment? 2) What are the narratives of women and nonbinary POC with CD about their experiences of racism, …

A Malicious Mediastinum: Rare Synovial Sarcoma, Julia Tu, Toluwanimi Oludiran-Ayoade, Valentina Turbay-Caballero, Ignatius Nyatsanza, Essam Mekhaiel

Advocate GME

No abstract provided.

High Heat Flux Dissipation Techniques Using Enhancement Structures And Subcooled Boiling Chamber For High Performance Computing Applications, Maharshi Y. Shukla

Theses

With a rising need for high-performance computing in data centers, enhanced heat dissipation from microprocessors becomes critical for maintaining their surface temperature in a compact setting. While air cooling has been sufficient until now, liquid cooling proves to be superior in its heat dissipation capabilities. The present work investigates enhancing liquid cooling with boiling and enhanced boiling structures in a novel subcooled boiling chamber. The single-phase forced convection heat transfer is first studied by enhancing the heat transfer performance (CHF and HTC) by more than 50 % with the injection of air bubbles at the heater surface. A self-sustaining method …

Proteomic Characterization And Cytotoxic Potential Of Proteins From Cuscuta (Cuscuta Epithymum (L.) Crude Herbal Product Against Mcf-7 Human Breast Cancer Cell Line, Umaima Akhtar, Yamna Khurshid, Bishoy El-Aarag, Basir Syed, Ishtiaq A. Khan, Keykavous Parang, Aftab Ahmed

Pharmacy Faculty Articles and Research

Background

The burden of breast cancer, the second leading cause of death worldwide, is increasing at an alarming rate. Cuscuta, used in traditional medicine for different ailments, including cancer, is known for containing phytochemicals that exhibit anticancer activity; however, the bioactivities of proteins from this plant remain unexplored. This study aimed to screen the cytotoxic potential of proteins from the crude herbal product of Cuscuta epithymum(L.) (CE) harvested from the host plants Alhagi maurorum and Medicago sativa.

Methods

The proteins from CE were extracted using a salting-out method, followed by fractionation with a gel filtration chromatography column. Gel-free shotgun …

Identifying Self-Efficacy Factors Of Agriscience Teachers When Working With Supervised Agricultural Experiences For Students With Disabilities, Saralyn L. Smith

LSU Master's Theses

The number of students receiving disability services annually in the U.S. has increased in the last decade. Even with this growing population of students with disabilities, research continues to show a lack of confidence of School Based Agricultural Education (SBAE) teachers in their ability and skills to include these students. The purpose of this qualitative study was to describe the factors that influence how SBAE teachers support students with disabilities in Supervised Agricultural Experience Programs and identify perceived obstacles SBAE teachers have regarding working with students with disabilities. Semi-structed interviews were conducted with twelve SBAE teachers to understand their lived …

Geographies Of Entitled Anger: Revanchist Populism In Brazil And Beyond, Ryan Centner, Mara Nogueira

Urban Studies and Planning Faculty Publications and Presentations

In an age of resurgent populism, emotional geographies play an underexamined yet pivotal role in explaining cross-class alliances that have enabled particularly angry forms of revanchist politics across world regions. This essay delineates the notion of “revanchist populism” and its grounding in “entitled anger,” as well as self-righteous geographical imaginations more broadly, to shed new light on the Brazilian case in recent years, which is further explored in this special issue. Beyond Brazil, we suggest how this approach can be used to bring a more geographical perspective to related iterations of revanchist populism elsewhere in the world and across the …

Assessing Associations Between Individual-Level Social Determinants Of Health And Covid-19 Hospitalizations: Investigating Racial/Ethnic Disparities Among People Living With Human Immunodeficiency Virus (Hiv) In The U.S. National Covid Cohort Collaborativ, Dimple Vaidya, Kenneth J. Wilkins, Eric Hurwitz, Jessica Y. Islam, Dongmei Li, Jing Sun, Sandra E. Safo, Jennifer M. Ross, Cara D. Varley, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Abstract Background: Leveraging the National COVID-19 Cohort Collaborative (N3C), a nationally sampled electronic health records repository, we explored associations between individual-level social determinants of health (SDoH) and COVID-19-related hospitalizations among racialized minority people with human immunodeficiency virus (HIV) (PWH), who have been historically adversely affected by SDoH. Methods: We retrospectively studied PWH and people without HIV (PWoH) using N3C data from January 2020 to November 2023. We evaluated SDoH variables across three domains in the Healthy People 2030 framework: (1) healthcare access, (2) economic stability, and (3) social cohesion with our primary outcome, COVID-19-related hospitalization. We conducted hierarchically nested additive …

Impacts Of Wildfires On Boreal Forest Ecosystem Carbon Dynamics From 1986 To 2020, Yiming Xu, Qianlai Zhuang, Bailu Zhao, Michael Billmire, Christopher Cook, Jeremy Graham, Nancy H. F. French, Ronald Prinn

Michigan Tech Publications

Wildfires significantly change boreal forest ecosystem carbon balance through both direct combustion and post-fire carbon dynamics. Affected vegetation influences soil thermal regime and carbon cycling by impacting the surface energy balance of boreal forests. This study uses a process-based biogeochemistry model to quantify carbon budget of North American boreal forests during 1986-2020 based on satellite-derived burn severity data. During the study period, burn severity generally increases. Fires remove ecosystem carbon of 2.4 Pg C and reduce net ecosystem production (NEP) from 32.6 to 0.8 Tg C yr−1, making the forest ecosystems lose 3.5 Pg C, shifting a carbon sink to …

Gilteritinib As Post-Transplant Maintenance For Aml With Internal Tandem Duplication Mutation Of Flt3, Mark J Levis, Geoffrey L Uy, Et Al.

2020-Current year OA Pubs

PURPOSE: Allogeneic hematopoietic cell transplantation (HCT) improves outcomes for patients with AML harboring an internal tandem duplication mutation of

METHODS: Adults with

RESULTS: Three hundred fifty-six participants were randomly assigned post-HCT to receive gilteritinib or placebo. Although RFS was higher in the gilteritinib arm, the difference was not statistically significant (hazard ratio [HR], 0.679 [95% CI, 0.459 to 1.005]; two-sided

CONCLUSION: Although the overall improvement in RFS was not statistically significant, RFS was higher for participants with detectable

Revealing Microbial Community Composition And Disinfection Efficacy Evaluation In Wholesale Pork Markets Through 16s Rdna Sequencing, Miao He, Lingyan Ma, Wentao Lv, Yingping Xiao, Hua Yang, Xiofan Wang, Jiangchao Zhao, Hangzhen Lan, Wen Wang, Xingning Xiao

Animal Science Faculty Publications and Presentations

This study has employed 16S rDNA analysis to elucidate the characteristics of the microbial community in the surroundings, facilities, and meat samples collected from a pork wholesale market with the aim of revealing bacterial contamination. In addition, the efficacy of sodium hypochlorite disinfectant was assessed by comparing the bacterial communities in the viable samples before and after disinfection. The bacterial abundances in meat, chopping boards, and knives were positively correlated (r > 0.95, p <  .05), suggesting potential cross-contamination risks during market transactions. The species richness indices for the external transport vehicles, pork hooks, and floors were significantly different from those of the samples taken after decontamination (p <  .05). Linear discriminant analysis Effect Size (LEfSe) analyses showed that Firmicutes, Proteobacteria, and Chloroflexi were significantly more abundant in the transaction period, whereas Bacteroidetes levels decreased compared to the clean-up period. NaClO disinfection …