Digital Commons Network^™

Accelerating Access To Sustainable Vaccine Adjuvant Technology, Chris Fox

Vaccine Technology IX

Please click Additional Files below to see the full abstract.

Prosocial Behavior, Sean Fernando, Claire Leach, Danielle Haake, Debra Bigelow-Davis, Jillian Stokes, Aj Kalawai'a, Nore Heinitz, Grace Bates

Psychology Student Publications

Prosocial behavior is a widely researched area of social psychology. It can be defined as the voluntary actions performed with the goal of benefiting others. This concept of helping others includes a wide range of actions, from simple acts such as holding the door open for someone to larger acts like donating money to charity (Peetz & Howard, 2022). This chapter will explore the topic of prosocial behavior by identifying the main types of prosocial behavior and the measure used to assess them, explaining the motivation behind prosocial behavior, and discussing various benefits and counterarguments to prosocial behavior.

Effects Of Functional Fatigue Protocol And Visual Information On Postural Control In Patients With Chronic Ankle Instability, Kyungeon Kim, Hyunsoo Kim, Kyeongtak Song, Suji Yoon, Eun Ji Hong, Hyung Gyu Jeon, Kyoung Uk Oh, Sae Yong Lee

Kinesiology Faculty Publications

Chronic ankle instability (CAI) patients often exhibit postural control deficits and rely on visual information to maintain static balance to compensate for decreased proprioception. Fatigue impairs neuromuscular control, in addition to postural control, in CAI patients. However, whether functional fatiguing exercises alter postural control and sensory organization strategies during single-leg balance tests in CAI patients remains unclear. This study involved a controlled trial on 28 CAI patients in a laboratory setting. Each participant performed a single-leg balance test with eyes open (EO) and eyes closed (EC) before and after a functional fatigue protocol. Two-way repeated-measures ANOVA evaluated fatigue (pre- vs. …

Implementation Of Post-Operative Discharge Instructions To Outpatients In A Pre-Procedural Endoscopy Suite Prior To Sedation, Kalaya Valdez

Doctor of Nursing Practice Final Manuscripts

Abstract

Introduction: The purpose of this evidence-based practice (EBP) Doctor of Nursing Practice (DNP) project is to improve overall patient satisfaction scores, patient safety and education retention postoperatively. The aim is to provide patients with the opportunity to review their discharge instructions and seek clarification prior to their procedure.

Background: Roughly 75 million endoscopies are conducted annually in the United States. The majority, 68%, are gastrointestinal endoscopies. Routine endoscopy procedures such as a colonoscopy or esophagogastroduodenoscopy utilize moderate sedation which is often a combination of midazolam and fentanyl. This combination reduces anxiety and discomfort during the procedure. The amnesic effects …

Politics And Social Welfare: Dynamics Of Social Assistance Programs On Electability In Indonesia, Willya Achmad

Jurnal Wacana Politik

This research aims to analyze the relationship between political policy and social welfare, with a focus on the dynamics of the Social Assistance Program (Bansos) and its impact on electability in Indonesia. In a dynamic political context, social assistance programs have a significant role in shaping public perceptions of government performance. This research uses a qualitative approach with descriptive methods. This research found that the main focus of social assistance is on the poor as the group most in need. Unfortunately, the practice of politicizing social assistance often occurs before general elections, obscuring its true purpose. Research notes cases of …

Combined Use Of Donepezil And Memantine Increases The Probability Of Five-Year Survival Of Alzheimer’S Disease Patients, Ehsan Yaghmaei, Hongxia Lu, Louis Ehwerhemuepha, Jianwei Zheng, Sidy Danioko, Ahmad Rezaie, Seyed Ahmad Sajjadi, Cyril Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

Background

Alzheimer’s disease (AD) is the most common neurodegenerative disease. Studying the effects of drug treatments on multiple health outcomes related to AD could be beneficial in demonstrating which drugs reduce the disease burden and increase survival.

Methods

We conducted a comprehensive causal inference study implementing doubly robust estimators and using one of the largest high-quality medical databases, the Oracle Electronic Health Records (EHR) Real-World Data. Our work was focused on the estimation of the effects of the two common Alzheimer’s disease drugs, Donepezil and Memantine, and their combined use on the five-year survival since initial diagnosis of AD patients. …

Raditation Test Report: Characterization Of Fairchild Imaging Cis2521 Cmos Focal Plane Array, Space Dynamics Laboratory

Space Dynamics Laboratory Publications

This report documents the results of radiation testing of Fairchild CIS2521 CMOS imaging sensor. Proton radiation measurements (both transient and total ionizing dose) were performed at the Crocker Nuclear Laboratory (CNL) of the University of California, Davis (UC Davis). Latchup characterization using Heavy Ion radiation was performed at the Texas A&M University Cyclotron Institute, Radiation Effects Facility.

The Social Justice Educational Assessment Scale: Filling A Gap In Social Justice Education Assessment And Evaluation, Jennifer R. Banas, Sarah Gershon

Health Sciences and Physical Education Faculty Publications

Nationally recognized social justice standards guide educators in developing social justice education. Absent from the guidance are tools to conduct initial formative assessment or to measure the impact of related instruction. To fill that gap, an academic researcher and 10th-grade teacher used a 3-phased, 9-step process to develop, pilot test, and evaluate a self-assessment tool called the Social Justice Educational Assessment Scale (SJEAS). In Phase 1, the team created the SJEAS items, aligning each with the Learning for Justice 9th–12th-grade social justice learning outcomes to ensure content validity. In Phase 2, they pretested the questions, revised the scale, and administered …

Amended Brief Of Amici Curiae Harold Hongju Koh And Diane Desierto In Support Of Petitioners-Appellees, Hyland Hunt, Ruthanne M. Deutsch, Diane A. Desierto

Court Briefs

No. 23-7174
Hulley Enterprises Ltd. v. Russian Federation

On Appeal from the U.S. District Court for the District of Columbia No. 1:14-cv-01996-BAH, Hon. Beryl A. Howell

From the Introduction and Summary of Argument

This appeal seeks to re-litigate a question that the Russian Federation had already lost with finality in the courts of the seat of arbitration (the Netherlands): namely, whether the Russian Federation ever agreed to arbitrate in the first place. Those arguments are identical to arguments the Russian Federation presented to Dutch courts more than six years ago in a failed effort to set aside the awards. Because …

Exploring 2d X-Ray Diffraction Phase Fraction Analysis With Convolutional Neural Networks: Insights From Kinematic-Diffraction Simulations, Weiqi Yue, Mohommad Redad Mehdi, Pawan K. Tripathi, Matthew A. Willard, Frank Ernst, Roger H. French

Faculty Scholarship

Deep-learning models are effective for analyzing the complex information in 2D X-ray diffraction (XRD) patterns. Accurately collecting parameters of the material sample is crucial during model training, significantly impacting model performance. In this study, we employ a kinematic-diffraction simulator to generate simulated 2D XRD patterns for Ti–6Al–4V alloy, allowing precise control of sample parameters. These simulated patterns are used to train convolutional neural networks, predicting β-phase volume fractions. The training data set consists exclusively of 2D XRD patterns with pure α- or pure β-phase, while the testing set incorporates patterns with intermediate phase volume fraction. In particular, we investigate how …

Dynamic Cbct Imaging Using Prior Model-Free Spatiotemporal Implicit Neural Representation (Pmf-Stinr), Hua-Chieh Shao, Tielige Mengke, Tinsu Pan, You Zhang

Faculty, Staff and Student Publications

Objective. Dynamic cone-beam computed tomography (CBCT) can capture high-spatial-resolution, time-varying images for motion monitoring, patient setup, and adaptive planning of radiotherapy. However, dynamic CBCT reconstruction is an extremely ill-posed spatiotemporal inverse problem, as each CBCT volume in the dynamic sequence is only captured by one or a few x-ray projections, due to the slow gantry rotation speed and the fast anatomical motion (e.g. breathing).Approach. We developed a machine learning-based technique, prior-model-free spatiotemporal implicit neural representation (PMF-STINR), to reconstruct dynamic CBCTs from sequentially acquired x-ray projections. PMF-STINR employs a joint image reconstruction and registration approach to address the …

Desert Mice Offer Insight Into Potential Climate Change Adaptations, Maeve Gifford

UNH Today Archive

No abstract provided.

Evaluating Effective Communication Of Baccalaureate Nursing Students, Christine N. Brockway

Dissertations

The purpose of this mixed methods study was to determine how communication evaluation by clinical faculty compared in a clinical setting versus a simulation setting for Bachelor of Science in Nursing (BSN) students. Fifty (50) BSN students from three different schools of nursing were scored using the Interprofessional Situation, Background, Assessment, Recommendation Nurse to Physician Rubric in both clinical and simulation settings by seven nursing faculty. Scoring for each student occurred in both settings during one semester. Following the evaluation, students and faculty were asked to participate in a focus group to discuss their experience. Results from this study showed …

News You Can Use: More To Play Therapy Than Play, Edwin Smith

University of Mississippi News

OXFORD, Miss. – To an outsider, it may look like children are simply playing with toys. But through this activity, children can reveal the struggles they are facing.

Functionalized Gold Nanoparticles And Halogen Bonding Interactions Involving Fentanyl And Fentanyl Derivatives, Molly M. Sherard, Jamie S. Kaplan, Jeffrey H. Simpson, Kevin W. Kittredge, Michael C. Leopold

Chemistry Faculty Publications

Fentanyl (FTN) and synthetic analogs of FTN continue to ravage populations across the globe, including in the United States where opioids are increasingly being used and abused and are causing a staggering and growing number of overdose deaths each year. This growing pandemic is worsened by the ease with which FTN can be derivatized into numerous derivatives. Understanding the chemical properties/behaviors of the FTN class of compounds is critical for developing effective chemical detection schemes using nanoparticles (NPs) to optimize important chemical interactions. Halogen bonding (XB) is an intermolecular interaction between a polarized halogen atom on a molecule and e−-rich …

The Unique Role Of The Second Coordination Sphere To Unlock And Control Catalysis In Nonheme Fe(Ii)/2-Oxoglutarate Histone Demethylase Kdm2a, Midhun George Thomas, Simahudeen Bathir Jaber Sathik Rifayee, Saket S. Chaturvedi, Koteswararao Gorantla, Walter White, Jon Wildey, Christopher J. Schofield, Christo Christov

Michigan Tech Publications

Nonheme Fe(II) and 2-oxoglutarate (2OG)-dependent histone lysine demethylases 2A (KDM2A) catalyze the demethylation of the mono- or dimethylated lysine 36 residue in the histone H3 peptide (H3K36me1/me2), which plays a crucial role in epigenetic regulation and can be involved in many cancers. Although the overall catalytic mechanism of KDMs has been studied, how KDM2 catalysis takes place in contrast to other KDMs remains unknown. Understanding such differences is vital for enzyme redesign and can help in enzyme-selective drug design. Herein, we employed molecular dynamics (MD) and combined quantum mechanics/molecular mechanics (QM/MM) to explore the complete catalytic mechanism of KDM2A, including …

Pancreatic Cancer And Venous Thromboembolism, Teagan Prouse, Mohammad A. Mohammad, Sonali Ghosh, Narender Kumar, Ma Lorena Duhaylungsod, Rinku Majumder, Samarpan Majumder

School of Graduate Studies Faculty Publications

Pancreatic ductal adenocarcinoma (PDAC) accounts for more than 90% of all pancreatic cancers and is the most fatal of all cancers. The treatment response from combination chemotherapies is far from satisfactory and surgery remains the mainstay of curative strategies. These challenges warrant identifying effective treatments for combating this deadly cancer. PDAC tumor progression is associated with the robust activation of the coagulation system. Notably, cancer-associated thrombosis (CAT) is a significant risk factor in PDAC. CAT is a concept whereby cancer cells promote thromboembolism, primarily venous thromboembolism (VTE). Of all cancer types, PDAC is associated with the highest risk of developing …

Beyond Vertigo: Vestibular, Aural, And Perceptual Symptoms In Vestibular Migraine, Claire E.J. Ceriani

Department of Jefferson Headache Center Papers and Presentations

PURPOSE: To review the vestibular, aural, and perceptual symptoms of vestibular migraine (VM) that may present alongside vertigo.

RECENT FINDINGS: Increased research attention to the wide spectrum of symptoms presenting in VM patients has improved understanding of this disorder, with recent identification of five different VM phenotypes. Research into the clinical overlap between VM and other chronic vestibular syndromes such as persistent postural-perceptual dizziness and mal-de-debarquement syndrome reveals a range of vestibular symptoms and hints at pathophysiological connections between migraine and vestibular dysfunction. Studies of migraine treatment for hearing loss suggest patients presenting with aural symptoms may have an underlying …

Frequent Disturbances Enhanced The Resilience Of Past Human Populations, Philip Riris, Fabio Silva, Enrico Crema, Alessio Palmisano, Erick Robinson, Peter E. Siegel, Jennifer C. French, Erlend Kirkeng Jørgensen, Shira Yoshi Maezumi, Steinar Solheim, Jennifer Bates, Benjamin Davies, Yongje Oh, Xiaolin Ren

Department of Anthropology Faculty Scholarship and Creative Works

The record of past human adaptations provides crucial lessons for guiding responses to crises in the future^1–3. To date, there have been no systematic global comparisons of humans’ ability to absorb and recover from disturbances through time^4,5. Here we synthesized resilience across a broad sample of prehistoric population time–frequency data, spanning 30,000 years of human history. Cross-sectional and longitudinal analyses of population decline show that frequent disturbances enhance a population’s capacity to resist and recover from later downturns. Land-use patterns are important mediators of the strength of this positive association: farming and herding societies are more …

Engaging Students In Partial Differential Equations Through Modeling Fourier's Law Of Conduction, Justin G. Trulen, Kayla Keller, John Sinclair, Lauren Meagher

CODEE Journal

In an effort to make active learning exercises in a partial differential equations course, we present a student activity modeling Fourier's law of conduction under the framework of the heat equation. An overview of the heat equation, including several avenues of study, is provided. Then we give an intuitive way of constructing the heat equation from a couple of fundamental properties of physics including Fourier's law of conduction. We outline an experiment that can be run to collect their own data to model Fourier's law of conduction as well as provide data we collected. We conclude with a student activity …

Investigating The Behavior Of Ternary Nbvzr Alloy And The Effect Of Zr Addition On The Mechanical And Microstructural Properties, Caelyn Walton-Macaulay

Mechanical Engineering and Materials Science Independent Study

This study investigates the microstructural and compositional evolution of a ternary NbVZr alloy under varying Zr concentrations, utilizing scanning electron microscopy (SEM) imaging and energy-dispersive X-ray spectroscopy (EDS) analysis. Results show consistent overall composition across different Zr concentrations, with observable Zr-enriched regions decreasing in frequency with increasing Zr content, potentially due to destabilization effects. Microstructural analysis reveals an increase in the area fraction occupied by dendrites as Zr content increases, prompting a decrease in the interdendritic phase. A comparison with an active concurrent work on the deposition of Nb to the ternary alloy highlights similarities and differences in phase distribution …

Draft Final 2024 Residential Metals Abatement Program (Rmap) Quality Assurance Project Plan (Qapp) Annual Update (Non-Residential Parcels And Residential Daycares), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

New York Law School Honors The Class Of 2024 At 132nd Commencement Exercises, Jennifer Bancamper

NYLS Community News

No abstract provided.

An Internal Validation Of The Ande Rapid Dna Instrument For Bone, Tissue, And Blood Samples, Alexandra Leichnam

Student Theses

The goal of this study is to internally validate the ANDE 6C Rapid DNA I-Chip reagent for use on disaster victim identification (DVI) samples. The internal validation tested nine samples each of postmortem blood, tissue, and bone. This study tested the instrument’s precision, accuracy, repeatability, and reproducibility. Precision and accuracy were tested by confirming that the same sample run on the ANDE instrument and the Power Plex Fusion amplification system produced a DNA profile that is consistent with the known profile. Repeatability was tested through confirming the correct results are obtained for sample runs performed by the same operator. Reproducibility …

Cotton/Soybean Insect Newsletter, May 23, 2024, Jeremy K. Greene

Clemson University Cotton/Soybean Insect Newsletter

No abstract provided.

Impact Of Combinatorial Histone Modifications On Acetyllysine Recognition By The Atad2 And Atad2b Bromodomains, Margaret Phillips, Kiera L Malone, Brian W Boyle, Cameron Montgomery, Isabelle A Kressy, Faith M Joseph, Kathleen M Bright, Samuel P Boyson, Sunsik Chang, Jay C Nix, Nicolas L Young, Victoria Jeffers, Seth Frietze, Karen C Glass

Faculty, Staff and Students Publications

The ATPase family AAA+ domain containing 2 (ATAD2) protein and its paralog ATAD2B have a C-terminal bromodomain (BRD) that functions as a reader of acetylated lysine residues on histone proteins. Using a structure–function approach, we investigated the ability of the ATAD2/B BRDs to select acetylated lysine among multiple histone post-translational modifications. The ATAD2B BRD can bind acetylated histone ligands that also contain adjacent methylation or phosphorylation marks, while the presence of these modifications significantly weakened the acetyllysine binding activity of the ATAD2 BRD. Our structural studies provide mechanistic insights into how ATAD2/B BRD-binding pocket residues coordinate the acetyllysine group in …

Our Body-Minds Are Not Apologies: How Systemic Oppression, Beauty Standards & Desirability Politics Impact The Body-Image & Sex Lives Of Trans & Non-Binary People With Physical (Dis)Abilities, Elm Mack

University Honors Theses

Due to the ableism, whiteness, and cisgender-heteropatriarchy in the US, people who are marked by racial, physical, neuro, and gendered differences are stereotypically considered to be less desirable. By applying a perspective informed by Disability Studies, Trans Studies, and Queer of Color Theory (including scholars like Eli Clare, Robert McRuer, Sonya Renee Taylor, Audre Lorde, Sami Schalk, Chris Finley, and Alicia Cox), I investigate how societal norms, beauty standards, and systemic oppression have disproportionately impacted the body-images and sex lives of trans and non-binary people with physical (dis)abilities. This thesis aims to shed light on the variety of ways in …

Joint Motion For Mediation

Catholic Dioceses in Bankruptcy

No abstract provided.

Post-Conviction Innocence Clinic Client’S Conviction Vacated After Years Of Work, Adele Bernhard

NYLS Community News

No abstract provided.

Determinants Of Implementation For Group Medical Visits For Patients With Chronic Pain: A Systematic Review, Isabel Roth, Malik Tiedt, Carrie Brintz, Ariana Thompson-Lastad, Gayla Ferguson, Erum Agha, Jennifer Holcomb, Paula Gardiner, Jennifer Leeman

Faculty, Staff and Student Publications

BACKGROUND: Despite the critical need for comprehensive and effective chronic pain care, delivery of such care remains challenging. Group medical visits (GMVs) offer an innovative and efficient model for providing comprehensive care for patients with chronic pain. The purpose of this systematic review was to identify barriers and facilitators (determinants) to implementing GMVs for adult patients with chronic pain.

METHODS: The review included peer-reviewed studies reporting findings on implementation of GMVs for chronic pain, inclusive of all study designs. Pubmed, EMBASE, Web of Science, and Cochrane Library were searched. Studies of individual appointments or group therapy were excluded. The Mixed …