Digital Commons Network^™

The Hidden Forms Of Violence In The Lives Of Professional Women In Tagamoa, New Cairo, Nouran Elhariry

Theses and Dissertations

The desire to craft new lifestyles is the main drive for the relocation to New Cairo among Egypt’s upper middle classes. This research is focusing on the upper middle class--people who still rely on their incomes from working to maintain their status—as opposed to the elite upper class, who rely on incomes from property, investments, inheritance, and other forms of intergenerational wealth. These communities were enmeshed in high degrees of domestic violence. The power-relations reconfigured in the domestic sphere, with increasing numbers of upper middle class women embarking on professional careers while navigating households and family relations, have opened the …

Plum Curculio (Conotrachelus Nenuphar), Kate V. Richardson, Marion Murray

All Current Publications

Plum curculio is a brown weevil (beetle with a snout) native to eastern North America, where it is a major pest of pome and stone fruits. It was detected in Box Elder County, Utah, in the early 1980s, and this population remains the only known infestation in western North America, where it is occasionally found in residential and wild fruit trees. Plum curculio is a quarantine pest in western North America (U.S. and Canada), and fruit grown in infested counties is restricted from being exported. Thus, it is a threat to Utah’s fruit industry and requires ongoing monitoring and management …

Cow-Calf Retained Ownership Analysis And Price Forecasting Using An Online Decision-Support Tool, Dillon M. Feuz

All Current Publications

Cow-calf producers frequently must make the decision to either sell their calves at weaning or soon thereafter or retain ownership of the calves through a background/growing phase. While the price they might receive at weaning may be known, there is great uncertainty about what cattle prices might be at the end of the retained ownership program. This fact sheet explains a method for reducing some of the uncertainty with cattle prices when the sale will occur months in the future and introduces a web-based decision-support tool that can help cattle producers quickly analyze the potential returns and risks from various …

Reflections On Zooarchaeology In East Polynesia: Human-Animal Interactions And Human Ecodynamics, Virginia L. Butler

Anthropology Faculty Publications and Presentations

The essay summarizes the key pillars of human ecodynamics (HE) research and then highlights the most trenchant ideas from each of the seven papers in the Special Issue, especially as they intersect with HE.

A Signal Injection Attack Against Zero Involvement Pairing And Authentication For The Internet Of Things, Isaac Ahlgren, Jack West, Kyu In Lee, George Thiruvathukal, Neil Klingensmith

Computer Science: Faculty Publications and Other Works

Zero Involvement Pairing and Authentication (ZIPA) is a promising technique for autoprovisioning large networks of Internet-of-Things (IoT) devices. In this work, we present the first successful signal injection attack on a ZIPA system. Most existing ZIPA systems assume there is a negligible amount of influence from the unsecured outside space on the secured inside space. In reality, environmental signals do leak from adjacent unsecured spaces and influence the environment of the secured space. Our attack takes advantage of this fact to perform a signal injection attack on the popular Schurmann & Sigg algorithm. The keys generated by the adversary with …

Dorsal Raphe Neurons Integrate The Values Of Reward Amount, Delay, And Uncertainty In Multi-Attribute Decision-Making, Yang-Yang Feng, Ethan S Bromberg-Martin, Ilya E Monosov

2020-Current year OA Pubs

The dorsal raphe nucleus (DRN) is implicated in psychiatric disorders that feature impaired sensitivity to reward amount, impulsivity when facing reward delays, and risk-seeking when confronting reward uncertainty. However, it has been unclear whether and how DRN neurons signal reward amount, reward delay, and reward uncertainty during multi-attribute value-based decision-making, where subjects consider these attributes to make a choice. We recorded DRN neurons as monkeys chose between offers whose attributes, namely expected reward amount, reward delay, and reward uncertainty, varied independently. Many DRN neurons signaled offer attributes, and this population tended to integrate the attributes in a manner that reflected …

Role Of The Afferent Lymph As An Immunological Conduit To Analyze Tissue Antigenic And Inflammatory Load, Padma P Nanaware, Cheryl F Lichti, Xiaoxiao Wan, Emil R Unanue, Et Al.

2020-Current year OA Pubs

The lymphatic fluid is the conduit by which part of the tissue "omics" is transported to the draining lymph node for immunosurveillance. Following cannulation of the pre-nodal cervical and mesenteric afferent lymphatics, herein we investigate the lymph proteomic composition, uncovering that its composition varies according to the tissue of origin. Tissue specificity is also reflected in the dendritic cell-major histocompatibility complex class II-eluted immunopeptidome harvested from the cervical and mesenteric nodes. Following inflammatory disruption of the gut barrier, the lymph antigenic and inflammatory loads are analyzed in both mice and subjects with inflammatory bowel diseases. Gastrointestinal tissue damage reflects the …

Airy-Beam Holographic Sonogenetics For Advancing Neuromodulation Precision And Flexibility, Zhongtao Hu, Yaoheng Yang, Leqi Yang, Yan Gong, Chinwendu Chukwu, Dezhuang Ye, Yimei Yue, Jinyun Yuan, Alexxai V Kravitz, Hong Chen

2020-Current year OA Pubs

Advancing our understanding of brain function and developing treatments for neurological diseases hinge on the ability to modulate neuronal groups in specific brain areas without invasive techniques. Here, we introduce Airy-beam holographic sonogenetics (AhSonogenetics) as an implant-free, cell type-specific, spatially precise, and flexible neuromodulation approach in freely moving mice. AhSonogenetics utilizes wearable ultrasound devices manufactured using 3D-printed Airy-beam holographic metasurfaces. These devices are designed to manipulate neurons genetically engineered to express ultrasound-sensitive ion channels, enabling precise modulation of specific neuronal populations. By dynamically steering the focus of Airy beams through ultrasound frequency tuning, AhSonogenetics is capable of modulating neuronal populations …

Disk Engine With Circumferential Swirl Radial Combustor, Brian T. Bohan, Marc D. Polanka, Bennett Staton

AFIT Patents

A disk engine and system configured to provide high power at a reduced axial length is disclosed herein. The disk engine includes a radial compressor, a compressor discharge manifold positioned circumferentially about compressor, a combustion chamber positioned within the discharge manifold and a radial turbine positioned radially inward of the combustion chamber.

A Shared Group Of Bacterial Taxa In The Duodenal Microbiota Of Undernourished Pakistani Children With Environmental Enteric Dysfunction, Najeeha T Iqbal, Robert Y Chen, Nicholas W Griffin, Matthew C Hibberd, Michael J Barratt, Jeffrey I Gordon, Et Al.

2020-Current year OA Pubs

Environmental enteric dysfunction (EED) is a subclinical syndrome of altered small intestinal function postulated to be an important contributor to childhood undernutrition. The role of small intestinal bacterial communities in the pathophysiology of EED is poorly defined due to a paucity of studies where there has been a direct collection of small intestinal samples from undernourished children. Sixty-three members of a Pakistani cohort identified as being acutely malnourished between 3 and 6 months of age and whose wasting (weight-for-length

Review: Myopathies In Broilers: Supply Chain Approach To Provide Solutions To Challenges Related To Raising Fast Growing Birds, Shai Barbut, Randolph Mitchell, Parker Hall, Craig Bacon, Ritchard Bailey, Casey M. Owens, Massimiliano Petracci

Poultry Science Faculty Publications and Presentations

This review is a summary of a Poultry Science Association symposium addressing myopathies in broilers’ breast meat, focusing on the interactions between genetics, nutrition, husbandry, and meat processing. The Pectoralis major myopathies (woody breast [WB]; white striping [WS]; spaghetti meat [SM]) and Pectoralis minor (“feathering”) are described, followed by discussing their prevalence, potential causes, current and future ways to mitigate, as well as detection methods (in live birds and meat) as well as ways to utilize affected meat. Overall, breast myopathies remain an important focus across the poultry industry and whilst a lot …

Navigating Fafsa, Rose Llanos

Faculty and Staff Publications & Presentations

Rose Llanos presented as a panelist for a webinar with Verto on Jun 25, 2024 for Next Chapter: College Expo, a dynamic week-long event designed to help students explore various aspects of the higher education journey. Over three days, participants will learn to navigate the college experience, connect with Verto alumni and direct transfer partners, and discover strategies to thrive as transfer students while building meaningful campus connections.

Injury-Induced Foxm1 Expression In The Mouse Kidney Drives Epithelial Proliferation By A Cyclin F-Dependent Mechanism, Megan L. Noonan, Yoshiharu Muto, Yasuhiro Yoshimura, Aidan Leckie-Harre, Haojia Wu, Vladimir V. Kalinichenko, Benjamin D. Humphreys, Monica Chang-Panesso

2020-Current year OA Pubs

Acute kidney injury (AKI) strongly upregulates the transcription factor Foxm1 in the proximal tubule in vivo, and Foxm1 drives epithelial proliferation in vitro. Here, we report that deletion of Foxm1 either with a nephron-specific Cre driver or by inducible global deletion reduced proximal tubule proliferation after ischemic injury in vivo. Foxm1 deletion led to increased AKI to chronic kidney disease transition, with enhanced fibrosis and ongoing tubule injury 6 weeks after injury. We report ERK mediated FOXM1 induction downstream of the EGFR in primary proximal tubule cells. We defined FOXM1 genomic binding sites by cleavage under targets and release using …

Malware Detection For Internet Of Things Using One-Class Classification, Tongxin Shi, Roy A. Mccann, Ying Huong, Wei Wang, Jun Kong

Electrical Engineering Faculty Publications and Presentations

The increasing usage of interconnected devices within the Internet of Things (IoT) and Industrial IoT (IIoT) has significantly enhanced efficiency and utility in both personal and industrial settings but also heightened cybersecurity vulnerabilities, particularly through IoT malware. This paper explores the use of one-class classification, a method of unsupervised learning, which is especially suitable for unlabeled data, dynamic environments, and malware detection, which is a form of anomaly detection. We introduce the TF-IDF method for transforming nominal features into numerical formats that avoid information loss and manage dimensionality effectively, which is crucial for enhancing pattern recognition when combined with n-grams. …

Hypoxia Inducible Factor 2Α Promotes Tolerogenic Macrophage Development During Cardiac Transplantation Through Transcriptional Regulation Of Colony Stimulating Factor 1 Receptor, Matthew Deberge, Samantha Schroth, Fanfan Du, Xin Yi Yeap, Jiao-Jing Wang, Mohammed Javeed Ansari, Edward B Thorp

Faculty, Staff and Student Publications

Solid organ transplantation mobilizes myeloid cells, including monocytes and macrophages, which are central protagonists of allograft rejection. However, myeloid cells can also be functionally reprogrammed by perioperative costimulatory blockade to promote a state of transplantation tolerance. Transplantation tolerance holds promise to reduce complications from chronic immunosuppression and promote long-term survival in transplant recipients. We sought to identify different mediators of transplantation tolerance by performing single-cell RNA sequencing of acute rejecting or tolerized cardiac allografts. This led to the unbiased identification of the transcription factor, hypoxia inducible factor (HIF)-2α, in a subset of tolerogenic monocytes. Using flow cytometric analyses and mice …

Car T-Cell Expansion: Harmful Or Helpful?, Anath C Lionel, Sattva S Neelapu

Faculty, Staff and Student Publications

No abstract provided.

A Spatiotemporal Map Of Co-Receptor Signaling Networks Underlying B Cell Activation, Katherine J Susa, Gary A Bradshaw, Robyn J Eisert, Charlotte M Schilling, Marian Kalocsay, Andrew C Kruse

Faculty, Staff and Student Publications

The B cell receptor (BCR) signals together with a multi-component co-receptor complex to initiate B cell activation in response to antigen binding. Here, we take advantage of peroxidase-catalyzed proximity labeling combined with quantitative mass spectrometry to track co-receptor signaling dynamics in Raji cells from 10 s to 2 h after BCR stimulation. This approach enables tracking of 2,814 proximity-labeled proteins and 1,394 phosphosites and provides an unbiased and quantitative molecular map of proteins recruited to the vicinity of CD19, the signaling subunit of the co-receptor complex. We detail the recruitment kinetics of signaling effectors to CD19 and identify previously uncharacterized …

Cracd Loss Induces Neuroendocrine Cell Plasticity Of Lung Adenocarcinoma, Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Gengyi Zou, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park

Faculty, Staff and Student Publications

Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells transform into neuroendocrine (NE) tumor cells. However, the mechanisms of NE cell plasticity remain unclear. CRACD (capping protein inhibiting regulator of actin dynamics), a capping protein inhibitor, is frequently inactivated in cancers. CRACD knockout (KO) is sufficient to de-repress NE-related gene expression in the pulmonary epithelium and LUAD cells. In LUAD mouse models, Cracd KO increases intratumoral heterogeneity with NE gene expression. Single-cell transcriptomic analysis showed that Cracd KO-induced NE cell plasticity is associated with cell de-differentiation and stemness-related pathway activation. The …

Cross-Sectional Analysis Of The Association Between Household Food Insecurity And Mental Health Conditions In Children Aged 5–11 Years In Canada, Justin Thielman, Sarah Orr, Saranya Naraentheraraja, Daniel Harrington, Sarah Carsley

Faculty, Staff and Student Publications

BACKGROUND: Children living in food insecure households have poorer mental health outcomes compared with their food-secure peers; however, the relationship between the severity of food insecurity and diagnosed mental health conditions in young children remains unknown. This study examined the association between household food insecurity and reported diagnosed mental health conditions among children aged 5-11 years in Canada.

METHODS: This study included 16 216 children aged 5-11 years living in Canada, from the 2019 Canadian Health Survey on Children and Youth. We measured household food insecurity using the Household Food Security Survey Module. We measured diagnosed mental health conditions by …

Centennial Records Of Microplastics In Lake Cores In Huguangyan Maar Lake, China, Qingsong Ji, Yanxia Zhang, Yubao Xia, Xinkai Wang, Maoyong He, Yi Yang, Clive E. Sabel, Bin Huang, Fengxiao Zhu, Min Shao, Enze Xie, Guojing Yan, Guonai Li, Aoyu Zhou, Huan He, Limin Zhang, Zhangdong Jin

School of Geography, Earth and Environmental Sciences

Microplastic records from lake cores can reconstruct the plastic pollution history. However, the associations between anthropogenic activities and microplastic accumulation are not well understood. Huguangyan Maar Lake (HML) is a deep-enclosed lake without inlets and outlets, where the sedimentary environment is ideal for preserving a stable and historical microplastic record. Microplastic (size: 10-500 μm) characteristics in the HML core were identified using the Laser Direct Infrared Imaging system. The earliest detectable microplastics appeared unit in 1955 (1.1 items g^-1). The microplastic abundance ranged from n.d. to 615.2 items g^-1 in 1955-2019 with an average of 134.9 items …

Neuropsychological Profiles Of Deployment-Related Mild Traumatic Brain Injury: A Limbic-Cenc Study, Emily L Dennis, Eamonn Kennedy, Deleene S Menefee, J Scott Parrott, Yuane Jia, Mary Jo V Pugh, William C Walker, David F Tate, David X Cifu, Jason M Bailie, Nicholas D Davenport, Sarah L Martindale, Maya O'Neil, Jared A Rowland, Randall S Scheibel, Scott R Sponheim, Maya Troyanskaya, Elisabeth A Wilde, Carrie Esopenko

Faculty, Staff and Students Publications

Background and objectives: Traumatic brain injury (TBI) is a concern for US service members and veterans (SMV), leading to heterogeneous psychological and cognitive outcomes. We sought to identify neuropsychological profiles of mild TBI (mTBI) and posttraumatic stress disorder (PTSD) among the largest SMV sample to date.

Methods: We analyzed cross-sectional baseline data from SMV with prior combat deployments enrolled in the ongoing Long-term Impact of Military-relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium prospective longitudinal study. Latent profile analysis identified symptom profiles using 35 indicators, including physical symptoms, depression, quality of life, sleep quality, postconcussive symptoms, and cognitive performance. It …

The Crosstalk Between Amyloid-Β, Retina, And Sleep For The Early Diagnosis Of Alzheimer's Disease: A Narrative Review, Isaiah Lorenzo De Guia, Shaun Eslick, Sharon L. Naismith, Swathi Kanduri, Tejal M. Shah, Ralph N. Martins

Research outputs 2022 to 2026

Alzheimer's disease (AD) is the most common type of dementia, which is characterised by progressive memory loss and accumulation of hallmark markers amyloid-β (Aβ) and neurofibrillary tangles in the diseased brain. The current gold standard diagnostic methods have limitations of being invasive, costly, and not easily accessible. Thus, there is a need for new avenues, such as imaging the retina for early AD diagnosis. Sleep disruption is symptomatically frequent across preclinical and AD subjects. As circadian activity, such as the sleep-wake cycle, is linked to the retina, analysis of their association may be useful additions for achieving predictive AD diagnosis. …

A Harmonized Public Resource Of Deeply Sequenced Diverse Human Genomes, Xuefang Zhao, Julia K Goodrich, Heesu Ally Kim, Michael W Wilson, Grace Tiao, Stephanie P Hao, Nareh Sahakian, Katherine R Chao, Mark A Walker, Yunfei Lyu, Heidi L Rehm, Benjamin M Neale, Michael E Talkowski, Mark J Daly, Harrison Brand, Konrad J Karczewski, Elizabeth G Atkinson, Alicia R Martin

Faculty, Staff and Students Publications

Underrepresented populations are often excluded from genomic studies owing in part to a lack of resources supporting their analyses. The 1000 Genomes Project (1kGP) and Human Genome Diversity Project (HGDP), which have recently been sequenced to high coverage, are valuable genomic resources because of the global diversity they capture and their open data sharing policies. Here, we harmonized a high-quality set of 4094 whole genomes from 80 populations in the HGDP and 1kGP with data from the Genome Aggregation Database (gnomAD) and identified over 153 million high-quality SNVs, indels, and SVs. We performed a detailed ancestry analysis of this cohort, …

Myeloablative Vs Nonmyeloablative Consolidation For Primary Central Nervous System Lymphoma: Results Of Alliance 51101, Tracy T Batchelor, Brad S Kahl, Nancy L Bartlett, Nina Wagner-Johnston, Et Al.

2020-Current year OA Pubs

Although it is evident that standard-dose whole-brain radiotherapy as consolidation is associated with significant neurotoxicity, the optimal consolidative strategy for primary central nervous system lymphoma (PCNSL) is not defined. We performed a randomized phase 2 clinical trial via the US Alliance cancer cooperative group to compare myeloablative consolidation supported by autologous stem cell transplantation with nonmyeloablative consolidation after induction therapy for PCNSL. To our knowledge, this is the first randomized trial to be initiated that eliminates whole-brain radiotherapy as a consolidative approach in newly diagnosed PCNSL. Patients aged 18 to 75 years were randomly assigned in a 1:1 manner to …

Quality Improvement: Naloxone Prescribing Practices For Paitent With An Opioid Patient Prescriber Agreement, Moniqueca Helms

Walden Dissertations and Doctoral Studies

The Substance Abuse Mental Health and Human Services Administration (SAMHSA) has set guidelines for opioid prescribing practices. The core principles of SAMHSA are to prevent overdose abuse and to provide appropriate treatment for those with an opioid abuse disorder. The concern addressed by the Doctor of Nursing Practice project was the gap in physician education regarding a Best Practice Alert (BPA) in the Electronic Medical Record that appears when prescribing an opioid to a patient without cancer. The alert indicates best practice is to prescribe naloxone with the opioid prescription. The naloxone BPA education project was implemented using the exploration, …

A Staff Education Program On The Education Of Nurses On Transgender Health Care, Diana Collins

Walden Dissertations and Doctoral Studies

In nursing education, both preregistration and continuing professional development, there is an absence of information about the specific needs of transgender people. The practicum site observed that education on the needs of the transgender community was lacking, discussing a discrepancy in the information offered and the scant attention paid to the unique requirements of transgender individuals. The goal of this project was to create a program that would raise staff members’ understanding of the exceptional health care requirements of the transgender population by providing them with an evidence-based assessment screening tool and training on transgender health care for nurses. The …

Strategies For Evaluating Training For Field Engineers In The Aerospace And Defense Industry, Nathan D. Johnson

Walden Dissertations and Doctoral Studies

Inefficient training strategies are just one of the many challenges field engineer managers face in the aerospace and defense industry. Aerospace and defense managers and customers are concerned because inefficient training strategies for field engineers impact how well they can effectively contribute to organizational and customer mission success in operations around the globe. Grounded in the Kirkpatrick model, the purpose of this qualitative pragmatic inquiry was to explore strategies aerospace and defense managers use to evaluate field engineer training programs. The participants were five aerospace and defense managers who successfully implemented training evaluation strategies. Data were collected from semistructured interviews …

Manufacturing Companies’ Strategies To Mitigate Supply Chain Disruptions, Trisha L. George

Walden Dissertations and Doctoral Studies

Supply chain disruption has the potential for adverse business outcomes. In manufacturing facility settings, leaders are concerned that supply chain disruption decreases the quality of productivity and profitability. Grounded in dynamic capability theory, the purpose of this qualitative pragmatic inquiry was to explore strategies leaders used to mitigate supply chain disruptions. The participants were six supply chain leaders from three manufacturing facilities located in Mexico who mitigated supply chain disruption. Data were collected using semistructured interviews and public records. Through thematic analysis, four themes were identified: (a) cultural differences, (b) communication, (c) organizational structures, and (d) disciplines. A key recommendation …

Foster Parents Assisting Transitioning Foster Care Youth In Maintaining Stable Housing, Cecilann Morrison

Walden Dissertations and Doctoral Studies

Foster Parents Assisting Transitioning Foster Care Youth in Maintaining Stable Housing by Cecilann Morrison MA, National University, 2013 BS, Fresno Pacific University, 2011 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Human and Social Service Walden University June 2024

Strategies For Evaluating Training For Field Engineers In The Aerospace And Defense Industry, Nathan D. Johnson

Walden Dissertations and Doctoral Studies

Inefficient training strategies are just one of the many challenges field engineer managers face in the aerospace and defense industry. Aerospace and defense managers and customers are concerned because inefficient training strategies for field engineers impact how well they can effectively contribute to organizational and customer mission success in operations around the globe. Grounded in the Kirkpatrick model, the purpose of this qualitative pragmatic inquiry was to explore strategies aerospace and defense managers use to evaluate field engineer training programs. The participants were five aerospace and defense managers who successfully implemented training evaluation strategies. Data were collected from semistructured interviews …