Digital Commons Network^™

“I Was Determined To Fulfill This Image Of Myself That I Wanted Of A ‘Good Asian Student’”: A Photovoice Study Of Asian American College Student Mental Health, Lalaine Sevillano, Joanna C. La Torre, Taylor A. Geyton

School of Social Work Faculty Publications and Presentations

Asian American (AsA) youth and emerging adults are growing at a faster rate than all other racial and ethnic populations in the United States. Burgeoning empirical evidence shows that they are experiencing increased adverse mental health outcomes since the start of the COVID-19 pandemic. Additionally, trends in AsA youth and emerging adults’ utilization and help-seeking behaviors remain low. Health equity scholars posit that the model minority stereotype continues to obscure and minimize these mental health disparities. The current study aims to contribute to this vital research through a Photovoice study with AsA emerging adults. Fourteen AsA undergraduate students (M age …

Metagenomic Analysis Of Antarctic Microbial Communities, David Michael Robinson

Biology ETDs

The research presented in this dissertation focuses on microbial roles in biogeochemical cycling in Antarctic aquatic environments. The major objective of my research was to examine the impact of biotic and abiotic pressures on nutrient cycling in microbially dominated systems. I used three perennially ice covered lakes in the McMurdo Dry Valleys (MDVs) along with subglacial lakes Whillans and Mercer as natural case studies. The MDVs are located in Victoria Land, East Antarctica and have been studied since 1993 as part of the McMurdo Long Term Ecological Research Project. Viruses in the MDVs were shown to be seasonally abundant and …

Neuroendocrine Gene Subsets Are Uniquely Dysregulated In Prostate Adenocarcinoma, Nicole M. Naranjo, Anne Kennedy, Anna Testa, Cecilia E. Verrillo, Adrian D. Altieri, Rhonda Kean, D. Craig Hooper, Jindan Yu, Jonathan Zhao, Oliver Abinader, Maxwell W. Pickles, Adam Hawkins, William Kevin Kelly, Ramkrishna Mitra, Lucia R. Languino

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Prostate cancer has heterogeneous growth patterns, and its prognosis is the poorest when it progresses to a neuroendocrine phenotype. Using bioinformatic analysis, we evaluated RNA expression of neuroendocrine genes in a panel of five different cancer types: prostate adenocarcinoma, breast cancer, kidney chromophobe, kidney renal clear cell carcinoma and kidney renal papillary cell carcinoma. Our results show that specific neuroendocrine genes are significantly dysregulated in these tumors, suggesting that they play an active role in cancer progression. Among others, synaptophysin (SYP), a conventional neuroendocrine marker, is upregulated in prostate adenocarcinoma (PRAD) and breast cancer (BRCA). Our analysis shows that SYP …

Nyls Congratulates Vincent Viola ’83 On Florida Panthers’ Stanley Cup Win, Jennifer Bancamper

NYLS Community News

No abstract provided.

Evangelist Queen Mobley Robinson

African American Funeral Programs

No abstract provided.

Examining Associations Between Smartphone Use And Clinical Severity In Frontotemporal Dementia: Proof-Of-Concept Study, Emily W Paolillo, Nupur Ghoshal, Et Al.

2020-Current year OA Pubs

BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a leading cause of dementia in individuals aged <65 years. Several challenges to conducting in-person evaluations in FTLD illustrate an urgent need to develop remote, accessible, and low-burden assessment techniques. Studies of unobtrusive monitoring of at-home computer use in older adults with mild cognitive impairment show that declining function is reflected in reduced computer use; however, associations with smartphone use are unknown.

OBJECTIVE: This study aims to characterize daily trajectories in smartphone battery use, a proxy for smartphone use, and examine relationships with clinical indicators of severity in FTLD.

METHODS: Participants were 231 adults (mean age 52.5, SD 14.9 years; n=94, 40.7% men; n=223, 96.5% non-Hispanic White) enrolled in the Advancing Research and Treatment of Frontotemporal Lobar Degeneration (ARTFL study) and Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS study) Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) Mobile App study, including 49 (21.2%) with mild neurobehavioral changes and no functional …

The Collaborative Assessment And Management Of Suicdality As A Single Session Intervention For Patients Admitted To Inpatient Psychiatric Care For Suicidal Thoughts And Behaviors, D Nicolas Oakey-Frost

LSU Doctoral Dissertations

Inpatient psychiatric care is a critical contact point for individuals experiencing suicidal thoughts and behaviors (STB). The Zero-Suicide framework provides useful scaffolding for improving suicide prevention within inpatient psychiatry (i.e., Assess, Intervene, and Monitor [AIM-SP]). Available evidence suggests instruments are available for evidence informed risk assessment but are hindered by low construct validity and a limited collaborative approach. Additionally, extant interventions do not typically target STB and are not optimized for inpatient psychiatric care. The Collaborative Assessment and Management of Suicidality (CAMS) meets the criteria of the Zero-Suicide Framework and is often leveraged as a single session intervention (SSI) but …

Emotional Reactivity And Recognition Deficits In Individuals With Callous-Unemotional (Cu) Traits: A Multilevel Meta-Analysis, Emily C. Kemp

LSU Doctoral Dissertations

Youth and adults with antisocial behavior present a significant mental health concern. Elevated callous-unemotional (CU) traits, characterized by deficient empathy and remorse, distinguish clinically important subgroups of antisocial individuals who present with more severe behavior and distinct cognitive-affective characteristics that may help to explain the underlying causes of their antisocial behavior and inform more effective treatments. Specifically, two mechanisms theorized to underlie the development of elevated CU traits by way of atypical empathy development are deficient reactivity to and recognition of others’ emotions. Though a substantive literature base reports associations between CU traits and emotional processing deficits, significant inconsistencies remain. …

Mettl3-Mediated Chromatin Contacts Promote Stress Granule Phase Separation Through Metabolic Reprogramming During Senescence, Chen Wang, Hideki Tanizawa, Connor Hill, Aaron Havas, Qiang Zhang, Xue Hao, Lu Wang, Hao Nie, Yuan Qi, Bin Tian, Alessandro Gardini, Andrew V Kossenkov, Aaron Goldman, Shelley L Berger, Ken-Ichi Noma, Peter D Adams, Rugang Zhang

Faculty, Staff and Student Publications

METTL3 is the catalytic subunit of the methyltransferase complex, which mediates m6A modification to regulate gene expression. In addition, METTL3 regulates transcription in an enzymatic activity-independent manner by driving changes in high-order chromatin structure. However, how these functions of the methyltransferase complex are coordinated remains unknown. Here we show that the methyltransferase complex coordinates its enzymatic activity-dependent and independent functions to regulate cellular senescence, a state of stable cell growth arrest. Specifically, METTL3-mediated chromatin loops induce Hexokinase 2 expression through the three-dimensional chromatin organization during senescence. Elevated Hexokinase 2 expression subsequently promotes liquid-liquid phase separation, manifesting as stress granule phase …

Contribution Of Matrix Metalloproteinase-2 And Matrix Metalloproteinase-9 To Upper Tract Urothelial Cancer Risk In Taiwan, Bo-Ren Wang, Hung-Huan Ma, Chao-Hsiang Chang, Cheng-Hsi Liao, Wen-Shin Chang, Ya-Chen Yang, Da-Tian Bau, Chia-Wen Tsai

Faculty, Staff and Student Publications

Matrix metalloproteinase (MMP)-2 and -9, which degrade type IV collagen, are linked to cancer invasion and metastasis. Gene polymorphisms in MMP-2 and MMP-9 can influence their function, impacting cancer development and progression. This study analyzed the association between polymorphisms MMP-2 rs243865 (C-1306T), rs2285053 (C-735T), and MMP-9 rs3918242 (C-1562T) with serum concentrations of these enzymes in upper tract urothelial cancer (UTUC) patients. We conducted a case-control study with 218 UTUC patients and 580 healthy individuals in Taiwan. Genotyping was performed using PCR/RFLP on DNA from blood samples, and MMP-2 and MMP-9 serum levels and mRNA expressions in 30 UTUC patients were …

Obituary: Prof. Donovan P Kelly (1940-2024), With A Review Of His Life's Work In Microbial Sulfur Metabolism, Autotrophy And C1 Metabolism, Rich Boden

School of Biological and Marine Sciences

No abstract provided.

Post-Baccalaureate Research Experiences For Students At Two Hispanic-Serving Institutions (Experience), Dessaray Monique Gorbett, Benjamin C. Flores, Cristina Villalobos, Sara E. Rodriguez, Ariana (Ari) Arciero, Josef A. Sifuentes

School of Mathematical & Statistical Sciences Faculty Publications

This study examines the implementation of a one-year program that offered post-baccalaureate research experiences to a cohort of recent STEM graduates from two large Hispanic-serving institutions. Both institutions are collaborators in an NSF Louis Stokes Alliance for Minority Participation (LSAMP) grant, which is dedicated to enhancing the academic experience of historically underrepresented minorities. Applicants were either self-nominated or were nominated by faculty to participate in the post-baccalaureate program. Following an application process that included an interview, selected participants were matched to research faculty and committed to engage in a high-impact research project for at least one semester and for up …

Correction: Graph Theory And Graph Neural Network Assisted High-Throughput Crystal Structure Prediction And Screening For Energy Conversion And Storage, Joshua Ojih, Mohammed Al-Fahdi, Yagang Yao, Jianjun Hu, Ming Hu

Faculty Publications

Correction for ‘Graph theory and graph neural network assisted high-throughput crystal structure prediction and screening for energy conversion and storage’ by Joshua Ojih et al., J. Mater. Chem. A, 2024, 12, 8502–8515, https://doi.org/10.1039/D3TA06190F.

On page 8511 in section 3.2 of the published article, the text “The single values of bonding and antibonding for each structure are obtained by performing integration over COHP curves for each atomic pair as evaluated by the LOBSTER package” should have included citations to six references. The missing references are listed below as ref. 1–6.

The Royal Society of Chemistry apologises for …

Strategies Used In United States E-Waste Recycling Businesses, Victor Odell Osborne

Walden Dissertations and Doctoral Studies

Increased consumer demand for the latest electrical and electronic technology and products has increased the amount of consumer and manufacturer-generated e-waste, leading to collection, handling, disposal, and environmental issues across the United States. Grounded in Bass’s curve theory, the purpose of this qualitative multiple case study was to explore strategies that southern United States company leaders used to recover funds from the disposal of e-waste. The participants included 13 leaders from 13 organizations in the solid waste recycling industry. Data were collected using semistructured interviews and peer-reviewed articles. Data analysis included occurrence frequency, with five themes emerging: (a) communication, (b) …

Effective Strategies To Improve Retention Of Sales Professionals In U.S. Large Retailers, Nicole Monique Jackson

Walden Dissertations and Doctoral Studies

Retail sales professionals have the highest turnover rates of approximately 40% in the United States. Retail business leaders see a continuous decline in sales due to understaffed workers in large apparel retailers leading to poor business performance. Grounded in Herzberg’s two-factor model theory, the purpose of this qualitative single case study was to explore strategies that some retail management teams use to retain sales professionals of large retailers in the Virginia peninsula and Portland, Oregon Metropolitan areas. The participants were five retail managers of four large apparel retailers who were successful in retaining sales professionals in their current roles within …

Natural Hazards Triggering Technological Disasters: Source Identification, Vulnerability, And Evaluation Of Emergency Preparedness In A Southern California City, Lisa Peumsang

Walden Dissertations and Doctoral Studies

Natural hazards triggering technological disasters (natech) events exist around the world and affect people, infrastructure, the economy, and environment but are not often considered for local hazard mitigation and emergency preparedness plans. The purpose of this qualitative case study was to identify (a) the natech event vulnerability of the target city, which is in the western United States, and potential sources for these events and (b) the extent to which the city’s hazard mitigation and emergency operations plans addressed natech events. The vulnerability assessment was performed through the lens of network risk theory and involved secondary data analysis of publicly …

Veterans Justice Outreach Program, Risk Of Recidivism, And Justice-Involved Veterans, Melody C. Weathers

Walden Dissertations and Doctoral Studies

To date, no study has examined whether the Veterans Justice Outreach (VJO) program influences recidivism once a justice-involved veteran (JIV) completes the program. Nor has a study examined the diagnoses and comorbidities between a JIV’s propensity for recidivism following separation from the VJO. One of the VJO program’s goals has been to end JIVs' contact with the criminal justice system. This study utilized a generic qualitative design that aimed to explore JIVs who received treatment from the VJO and whether there was an effect on their risk of recidivism. Additional elements for exploration included posttraumatic stress disorder, traumatic brain disorder, …

Strategies Used In United States E-Waste Recycling Businesses, Victor Odell Osborne

Walden Dissertations and Doctoral Studies

Increased consumer demand for the latest electrical and electronic technology and products has increased the amount of consumer and manufacturer-generated e-waste, leading to collection, handling, disposal, and environmental issues across the United States. Grounded in Bass’s curve theory, the purpose of this qualitative multiple case study was to explore strategies that southern United States company leaders used to recover funds from the disposal of e-waste. The participants included 13 leaders from 13 organizations in the solid waste recycling industry. Data were collected using semistructured interviews and peer-reviewed articles. Data analysis included occurrence frequency, with five themes emerging: (a) communication, (b) …

Effective Strategies To Improve Retention Of Sales Professionals In U.S. Large Retailers, Nicole Monique Jackson

Walden Dissertations and Doctoral Studies

Retail sales professionals have the highest turnover rates of approximately 40% in the United States. Retail business leaders see a continuous decline in sales due to understaffed workers in large apparel retailers leading to poor business performance. Grounded in Herzberg’s two-factor model theory, the purpose of this qualitative single case study was to explore strategies that some retail management teams use to retain sales professionals of large retailers in the Virginia peninsula and Portland, Oregon Metropolitan areas. The participants were five retail managers of four large apparel retailers who were successful in retaining sales professionals in their current roles within …

Rapid Video Prototyping And Content Creation Using Generative Artificial Intelligence, Krishna Chytanya Ayyagari

Defensive Publications Series

Traditional video production is a resource intensive process, requiring significant time and large financial investment. A common practice in entertainment and gaming industries is to generate prototypes or previews of video content before final video creation. This disclosure describes the use of generative artificial intelligence to automatically generate short video content that can be used directly as short-form video content (e.g., advertisements, short-form videos, etc.) or can be used as part of a larger video that may also include human-created content. Video generation requests are received as prompts, which are refined and processed to ensure compliance. Generative video libraries are …

Detection Of Anomalies In Visual Elements, Shu-Wei Cheng, Grant Kennell, Fei Wang

Defensive Publications Series

As new versions of an app or other software are checked into a version control system, bugs can be introduced that are undetected by regression testing. Apps or software that have visual elements (VE) or components are particularly susceptible because regression tests usually do not include comparisons of viewports as seen by a user. This disclosure describes techniques to detect bugs in successive versions of a software under test by translating visual elements into quantitative metrics; by detecting anomalies, e.g., sudden spikes, cliffs, or drops, in quantitative metrics; and by mapping the detected anomaly to particular versions of constituent module(s) …

Why Medicine Needs The Humanities: An Argument For Arguments, Suraj R. Nyalakonda, Md

The Medicine Forum

As medicine plunges deeper into the 21st century, there appear to be three forces coming together that hold both promise and peril as technology’s march of progress continues unabated through the healing profession.

Musings Of A House Staff Officer On The Wards, Suraj R. Nyalakonda, Md

The Medicine Forum

I am told I am part of the house staff. I am told I am a resident. I am told my predecessors, who are now my teachers, earned the title of resident by residing at their place of work, which was also their place of passion, which was the hospital, that institution that, with the advent of the industrial revolution, came to be a producer of health, a fixer of bodies. I am also now told that we residents are increasingly the sort of thing that can burn out. The other thing I know that can burn out - when …

Shadows And Echoes Of Understanding: A Physician's Reflection On Plato's Allegory Of The Cave And Medicine, Michael Dong, Md, Tamar Wolinsky Md, Benjamin Claxton, Md, Mph, Chantel Venkataraman, Md

The Medicine Forum

Plato's Allegory of the Cave offers a lens through which one can contemplate the complexities of medicine, where the shadows and echoes of illness obscure the true forms of disease. As physicians, we seek to illuminate the shadows that shroud our patients’ understanding of their illnesses and provide clarity to help patients navigate the labyrinth of diagnoses and treatments.

Unmasked, Rehana Persaud, Ms

The Medicine Forum

The world was quiet

A virtual reality

I existed

you lived

in it

We lived

In

a

world,

that was h u s h e d …

A quiet one

The silence was DeafeninG

But

I HEARD what consumed

me

Quantum Of Solace, Jeffrey White, Md

The Medicine Forum

Dr. R was back on 3 West and looking the worse for wear. Colon cancer, partial resection, bowel obstruction, ischemia, second surgery, bleeding, third surgery, infectious colitis, four days in the ICU—this 90-year-old man, who his wife assured us was bright and vibrant before his admission, was not long for this world. His baseline dementia had begotten daily delirium. He had had heart failure and COPD before his admission, and his fluid retention had swelled his already substantial body habitus to uncomfortable proportions.

Cadaver Dissection — A Reminder Of Humanity, Samuel De Matte, Ms

The Medicine Forum

I wash my hands, pick up a pair of purple forearm gloves, and gown up in an apron. The large overhead lights flood the room with sterile illumination, reflecting off the metal cabinets onto the white walls. I approach one of the thirty-four body bags with a group of classmates. The slow growl of the zipper fills the otherwise silent room. We pull back the formaldehyde-soaked sheet to reveal our cadaver. We all notice the rose tattoo on her chest.

A Curious Case Of Ards, Normonique Dyer, Do

The Medicine Forum

Acute respiratory distress syndrome (ARDS) is a well-known description of progressive respiratory decline. ARDS can be suspected in patients that meet the following criteria: (1) progressive dyspnea with onset within 1 week of a suspected clinical insult, (2) reduction in arterial oxygen saturation, and (3) bilateral alveolar infiltrates not due to a primary cardiogenic process.¹ The management of ARDS is largely unchanged regardless of the etiology and thus will not be within the scope of discussion for this report. However, the etiology of ARDS is of significance given that the cause of a patient’s respiratory failure has prognostic implications. …

A Case Of Reactivation Tuberculosis, Edwin Perez, Md, Avish Patel, Md, Taha Awan, Md, Amman Bhasin, Md, Gautam George, Md

The Medicine Forum

Approximately 22 percent of the world population is estimated to be infected with Mycobacterium tuberculosis. The largest number of cases are seen in Sub-Saharan Africa, India, and the islands of Southeast Asia, while North America and Western Europe are “low incidence” regions.¹ In the US, most cases are seen in foreign-born individuals who emigrate from high-incidence countries. Despite the low incidence in the US, prevention and control of Tuberculosis (TB) remain an important component of Public Health.² Here we present a case of a patient of Vietnamese origin with reactivation TB and rare manifestations of TB.

Nodular Al Amyloidosis — An Unusual Etiology Of A Solitary Pulmonary Nodule, Benjamin B. Claxton, Md, Mph, Shruti Nanivadekar, Md, Stacey Gargano, Md, Prarthna C. Kulandaisamy, Md

The Medicine Forum

Solitary pulmonary nodules (SPN) are defined as single intraparenchymal opacities less than 3 centimeters. The differential diagnosis of the SPN is broad. AL amyloidosis is a protein conformational disease which occurs when certain monoclonal light chains develop an unstable tertiary structure with resultant polymerization of insoluble amyloid fibrils that deposit in the extracellular space of sundry tissues. In the lung, diffuse interstitial amyloid deposition is the most common form of the disease.