Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 363811 - 363840 of 5209380

Full-Text Articles in Entire DC Network

Normalization Of Rapid Force To Peak Force In An Isometric Hamstring Assessment Using Force Plates, R. Barber, J. T. Fahey, P. Comfort, N. J. Ripley Jul 2024

Normalization Of Rapid Force To Peak Force In An Isometric Hamstring Assessment Using Force Plates, R. Barber, J. T. Fahey, P. Comfort, N. J. Ripley

Research outputs 2022 to 2026

Purpose: The aim of this investigation was to determine the reliability of normalizing rapid force (RF) production to peak force assessed during an isometric knee flexor assessment, and to present a novel method of classifying athletes' potential training needs within the 90–90 isometric hamstring assessment. Procedures: Twenty elite female soccer players (age: 20.7 ± 4.7 years; height: 168.2 ± 5.5 cm; body mass: 62.8 ± 7.0 kg), with no recent (>6 months) history of hamstring strain injury, volunteered to participate in the study. Following a standardized warm-up, each participant performed three maximal isometric hamstring contractions, with their heel resting …


Prognostic Value Of The 1-Min Sit-To-Stand Test To Predict Post-Operative Complications In Patients With Lung Cancer Elected For Lung Resection, Kirsten Quadflieg, Rachael Higgins, Eva Arents, Heleen Demeyer, Maarten Criel, Marc Daenen, David Ruttens, Michiel Thomeer, Dieter Stevens, Andrew Maiorana, Martijn A. Spruit, Vinicius Cavalheri, Chris Burtin Jul 2024

Prognostic Value Of The 1-Min Sit-To-Stand Test To Predict Post-Operative Complications In Patients With Lung Cancer Elected For Lung Resection, Kirsten Quadflieg, Rachael Higgins, Eva Arents, Heleen Demeyer, Maarten Criel, Marc Daenen, David Ruttens, Michiel Thomeer, Dieter Stevens, Andrew Maiorana, Martijn A. Spruit, Vinicius Cavalheri, Chris Burtin

Research outputs 2022 to 2026

No abstract provided.


Preparation, Reaction Mechanism And Microwave-Absorbing Application Of Functional Transition Metal Carbide/Nitride Ceramic Materials, Zhengbo Xu, Shu Qing Kou, Bai Xin Dong, Xinmiao Zhong, Hongyu Yang, Lin Liu, Ruifen Guo, Shi Li Shu, Feng Qiu, Lai Chang Zhang Jul 2024

Preparation, Reaction Mechanism And Microwave-Absorbing Application Of Functional Transition Metal Carbide/Nitride Ceramic Materials, Zhengbo Xu, Shu Qing Kou, Bai Xin Dong, Xinmiao Zhong, Hongyu Yang, Lin Liu, Ruifen Guo, Shi Li Shu, Feng Qiu, Lai Chang Zhang

Research outputs 2022 to 2026

The explosive growth of wireless communications and electronic devices has brought electromagnetic radiation's harmfulness and hidden trouble to light, which has a major impact on electrical equipment's ability to function normally. MXene, a material with favorable features like conductivity, a unique two-dimensional multiple-layer structure and abundant surface functional groups, has made it a viable contender for high-performance microwave-absorbers. This article introduces the synthesis strategy of MXene/MXene-based materials and their parent phase MAX, comprehensively summarizes and analyzes the current progress in the study on the microwave-absorbing properties of MXene/MXene-based materials, analyzes the main problems and bottlenecks. Future research directions for MXene …


Share Pledge And Accounting Conservatism In Share-Pledging Firms: Evidence From A Natural Experiment In China, Xin Wang, Yue Sun, Yanlin Li, Cuijiao Zhang Jul 2024

Share Pledge And Accounting Conservatism In Share-Pledging Firms: Evidence From A Natural Experiment In China, Xin Wang, Yue Sun, Yanlin Li, Cuijiao Zhang

Research outputs 2022 to 2026

This paper focuses on firms in which insiders pledge their shares as collateral for loans. By investigating a natural experiment—China’s enactment of provisions on share reductions that restrict pledge creditors’ cashing-out behavior—we find that pledging firms exhibited more conservative financial reporting after the implementation than non-pledging firms. This effect was pronounced in firms with a higher ratio of pledged shares, a longer maturation period of the pledged shares, and more concentrated pledge creditors. Additionally, we show that pledging firms increased their accounting conservatism after the shock, leading to a lower risk of margin calls and stock price crashes. The effect …


Strengthening Power Systems For Net Zero: A Review Of The Role Of Synchronous Condensers And Emerging Challenges, Hamid Soleimani, Daryoush Habibi, Mehrdad Ghahramani, Asma Aziz Jul 2024

Strengthening Power Systems For Net Zero: A Review Of The Role Of Synchronous Condensers And Emerging Challenges, Hamid Soleimani, Daryoush Habibi, Mehrdad Ghahramani, Asma Aziz

Research outputs 2022 to 2026

System strength is both supplied and demanded in a power system during normal operations and in the presence of disturbances. This is characterised by stable voltage and frequency, supporting renewable generation such as wind and solar. Because the retirement of synchronous generators reduces system strength supply, and the connection of new inverter-based resource (IBR) generators increases demand, there is an urgent need for new sources of system strength. This paper provides an overview of the challenges brought about by grid modernisation. It highlights tangible solutions provided by synchronous condensers (SCs) to bolster grid strength, stability, and reliability while accommodating the …


The Mccusker Subjective Cognitive Impairment Inventory (Mcsci): A Novel Measure Of Perceived Cognitive Decline, Hamid R. Sohrabi, Brandon E. Gavett, Michael Weinborn, Craig P. Speelman, Romola S. Bucks, Ralph N. Martins Jul 2024

The Mccusker Subjective Cognitive Impairment Inventory (Mcsci): A Novel Measure Of Perceived Cognitive Decline, Hamid R. Sohrabi, Brandon E. Gavett, Michael Weinborn, Craig P. Speelman, Romola S. Bucks, Ralph N. Martins

Research outputs 2022 to 2026

Background: Subjective cognitive decline (SCD), i.e. self/other-reported concerns on one’s cognitive functioning without objective evidence of significant decline, is an indicator of dementia risk. There is little consensus on reliability and validity of the available SCD measures. Therefore, introducing a novel and psychometrically sound measure of SCD is timely.

Objective: The psychometric properties of a new SCD measure, the McCusker Subjective Cognitive Impairment Inventory–Self-Report (McSCI-S), are reported.

Methods: Through review of previously published measures as well as our clinical and research data on people with SCD, we developed a 46-item self-report questionnaire to assess concerns on six cognitive domains, namely, …


The Relationship Between Diet, Depression, And Alzheimer's Disease: A Narrative Review, Hilal Salim Said Al Shamsi, Stephanie R. Rainey-Smith, Samantha L. Gardener, Hamid R. Sohrabi, Rodrigo Canovas, Ralph N. Martins, Warnakulasuriya Mary Ann Dipika Binosha Fernando Jul 2024

The Relationship Between Diet, Depression, And Alzheimer's Disease: A Narrative Review, Hilal Salim Said Al Shamsi, Stephanie R. Rainey-Smith, Samantha L. Gardener, Hamid R. Sohrabi, Rodrigo Canovas, Ralph N. Martins, Warnakulasuriya Mary Ann Dipika Binosha Fernando

Research outputs 2022 to 2026

Purpose of Review: This narrative review evaluates the role of diet in the relationship between depression and Alzheimer's disease (AD). Recent Findings: AD and depression are often comorbid, and depression appears to independently increase the future risk of AD. Evidence suggests diet influences the risk of both conditions directly and indirectly. Diet impacts neurochemical and biological processes that may affect the development and progression of depression and cognitive dysfunction. The dietary components offering the greatest protection against depression and AD are yet to be determined. Current evidence highlights the importance of polyphenolic compounds, folate, B vitamins, and polyunsaturated fatty acids, …


Transdermal Oestradiol And Exercise In Androgen Deprivation Therapy (Estracise): Protocol, Ilkka Jussila, Juha P. Ahtiainen, Eija K. Laakkonen, Aino Siltari, Antti Kaipia, Tiina Jokela, Minta Kärkkäinen, Rob Newton, Truls Raastad, Heini Huhtala, Teemu J. Murtola, Heikki Seikkula Jul 2024

Transdermal Oestradiol And Exercise In Androgen Deprivation Therapy (Estracise): Protocol, Ilkka Jussila, Juha P. Ahtiainen, Eija K. Laakkonen, Aino Siltari, Antti Kaipia, Tiina Jokela, Minta Kärkkäinen, Rob Newton, Truls Raastad, Heini Huhtala, Teemu J. Murtola, Heikki Seikkula

Research outputs 2022 to 2026

Objective: To report the protocol of a study evaluating the efficacy of transdermal oestradiol (E2) gel in reducing the adverse effects of androgen deprivation therapy (ADT), specifically on sexual function, and to assess the utility of E2 in combination with supervised exercise. Study Design and Methods: The primary endpoint of this open-label Phase IIA randomized controlled trial is the efficacy of transdermal E2 gel. Secondary endpoints include: (i) the occurrence of ADT-induced adverse effects; (ii) the safety and tolerability of E2; (iii) the impact of E2 with or without exercise on physical, physiological, muscle, and systemic biomarkers; and (iv) quality …


Trust Dynamics In Sharing Economy Services During A Crisis: A Comparison Between Airbnb And Uber, Alireza Amrollahi, Tyge F. Kummer, Mehdi Rajaeian, Arghavan Hadinejad Jul 2024

Trust Dynamics In Sharing Economy Services During A Crisis: A Comparison Between Airbnb And Uber, Alireza Amrollahi, Tyge F. Kummer, Mehdi Rajaeian, Arghavan Hadinejad

Research outputs 2022 to 2026

This study investigates trust dynamics in sharing economy services during the COVID-19 crisis, comparing Airbnb and Uber as prominent representatives of accommodation and transportation services in tourism. Guided by two research questions, the study first explores the antecedents and mechanisms of trust creation on these platforms and then examines how the global pandemic affected trust in these services. The findings reveal that structural assurance, privacy protection, and social influence (only for Uber) are key antecedents of trust. Trust, in turn, significantly influences perceived usefulness and the intention to use both platforms. The results also show that perceived risk, heightened by …


Application Of Multilayer Perceptron Artificial Neural Network (Mlp-Ann) Algorithm For Pm2.5 Mass Concentration Estimation During Open Biomass Burning Episodes In Thailand, P. Paluang, W. Thavorntam, W. Phairuang Jul 2024

Application Of Multilayer Perceptron Artificial Neural Network (Mlp-Ann) Algorithm For Pm2.5 Mass Concentration Estimation During Open Biomass Burning Episodes In Thailand, P. Paluang, W. Thavorntam, W. Phairuang

Research outputs 2022 to 2026

Open biomass burning (OBB) is the main cause of air pollution in Northern Thailand, where PM2.5 concentrations exceed Thailand's air quality standards annually during the January–April (dry season). The air emissions from databases that detail the pollutants discharged into the atmosphere from specific sources of air pollution are crucial for monitoring air pollution. However, this data has been poorly studied in Thailand. This study estimated ground-level PM2.5 concentration in Northern Thailand using the Multilayer Perceptron Artificial Neural Networks (MLP-ANN) model, integrating the in-depth data as input variables. The 10-fold cross-validation approach was applied to validate the model's performance. The meteorological …


Open-Label, Dose-Escalation Fight-101 Study Of Pemigatinib Combined With Targeted Therapy, Chemotherapy, Or Immunotherapy In Patients With Advanced Malignancies, M Saleh, M Barve, V Subbiah, K P Papadopoulos, D Morgensztern, N B Mettu, S Roychowdhury, I Spanggaard, M L Veronese, C Tian, I M Silverman, M Gutierrez Jul 2024

Open-Label, Dose-Escalation Fight-101 Study Of Pemigatinib Combined With Targeted Therapy, Chemotherapy, Or Immunotherapy In Patients With Advanced Malignancies, M Saleh, M Barve, V Subbiah, K P Papadopoulos, D Morgensztern, N B Mettu, S Roychowdhury, I Spanggaard, M L Veronese, C Tian, I M Silverman, M Gutierrez

2020-Current year OA Pubs

BACKGROUND: Pemigatinib is an oral, potent, selective fibroblast growth factor receptor (FGFR) 1-3 inhibitor. FIGHT-101, a three-part, open-label, first-in-human, phase I/II study (NCT02393248), evaluated pemigatinib in patients with advanced solid tumors. In parts 1 and 2, pemigatinib monotherapy had a manageable safety profile and antitumor activity in FGFR-altered tumors. Part 3 (pemigatinib combination therapies) results are presented here.

PATIENTS AND METHODS: Patients received 9, 13.5, or 20 mg oral once-daily pemigatinib on continuous or intermittent schedules with gemcitabine and cisplatin (pemi/gem/cis), docetaxel (pemi/doc), trastuzumab (pemi/tras), pembrolizumab (pemi/pembro), or retifanlimab (pemi/reti) irrespective of whether the tumor was confirmed as FGFR altered. …


Cost Effectiveness Analysis Of A Fixed Dose Combination Pill For Primary Prevention Of Cardiovascular Disease From An Individual Participant Data Meta-Analysis, Andre Lamy, Wesley Tong, Philip Joseph, Peggy Gao, Mark D Huffman, Gholamreza Roshandel, Reza Malekzadeh, Patricio Lopez-Jaramillo, Prem Pais, Denis Xavier, Alvaro Avezum, Antonio L Dans, Habib Gamra, Salim Yusuf Jul 2024

Cost Effectiveness Analysis Of A Fixed Dose Combination Pill For Primary Prevention Of Cardiovascular Disease From An Individual Participant Data Meta-Analysis, Andre Lamy, Wesley Tong, Philip Joseph, Peggy Gao, Mark D Huffman, Gholamreza Roshandel, Reza Malekzadeh, Patricio Lopez-Jaramillo, Prem Pais, Denis Xavier, Alvaro Avezum, Antonio L Dans, Habib Gamra, Salim Yusuf

2020-Current year OA Pubs

BACKGROUND: Cardiovascular disease (CVD) continues to impart a large burden on the global population, especially in lower income countries where affordability limits the use of cardiovascular medicines. A fixed dose combination strategy of at least 2 blood pressure lowering medications and a statin with aspirin in a single pill has been shown to reduce the risk of incident CVD by 38% in primary prevention in a recent meta-analysis. We report the in-trial (median follow-up: 5 years) cost-effectiveness of a fixed dose combination (FDC) pill in different income groups based on data from that meta-analysis.

METHODS: Countries were categorized using World …


Tumor-Informed Deep Sequencing Of Ctdna Detects Minimal Residual Disease And Predicts Relapse In Osteosarcoma, Yiwei Fu, Albert H Kim, Dimitrios Mathios, Et Al. Jul 2024

Tumor-Informed Deep Sequencing Of Ctdna Detects Minimal Residual Disease And Predicts Relapse In Osteosarcoma, Yiwei Fu, Albert H Kim, Dimitrios Mathios, Et Al.

2020-Current year OA Pubs

BACKGROUND: Current surveillance modalities of osteosarcoma relapse exhibit limited sensitivity and specificity. Although circulating tumor DNA (ctDNA) has been established as a biomarker of minimal residual disease (MRD) in many solid tumors, a sensitive ctDNA detection technique has not been thoroughly explored for longitudinal MRD detection in osteosarcoma.

METHODS: From August 2019 to June 2023, 59 patients diagnosed with osteosarcoma at the First Affiliated Hospital of Sun Yat-sen University were evaluated in this study. Tumor-informed MRD panels were developed through whole exome sequencing (WES) of tumor tissues. Longitudinal blood samples were collected during treatment and subjected to multiplex PCR-based next-generation …


Diagnostic Efficacy And Clinical Impact Of Image-Guided Core Needle Biopsy Of Suspected Vertebral Osteomyelitis, Winston L Winkler, Ige A George, Sumanth Gandra, Jonathan C Baker, Anderanik Tomasian, Benjamin Northrup, Theodore L Vander Velde, Travis J Hillen, Chongliang Luo, Resten Imaoka, Gino M Dettorre, Jack W Jennings Jul 2024

Diagnostic Efficacy And Clinical Impact Of Image-Guided Core Needle Biopsy Of Suspected Vertebral Osteomyelitis, Winston L Winkler, Ige A George, Sumanth Gandra, Jonathan C Baker, Anderanik Tomasian, Benjamin Northrup, Theodore L Vander Velde, Travis J Hillen, Chongliang Luo, Resten Imaoka, Gino M Dettorre, Jack W Jennings

2020-Current year OA Pubs

OBJECTIVES: The diagnostic yield and clinical impact of image-guided core needle biopsy (ICNB) of suspected vertebral osteomyelitis in adults is heterogenous in published studies owing to small sample sizes, indicating the need for large cohort studies.

METHODS: A retrospective analysis of ICNBs was performed from 2010 to 2021 for patients with imaging findings consistent with vertebral osteomyelitis. For each biopsy, a series of factors were analyzed, as well as if histopathology was diagnostic of osteomyelitis and if microbiological cultures were positive. In addition, it was recorded in what way biopsy influenced clinical management regarding antimicrobial treatment. A multivariate statistical analysis …


Pharmacokinetic Modeling Of The Effect Of Tariquidar On Ondansetron Disposition Into The Central Nervous System, Manting Chiang, Hyunmoon Back, Jong Bong Lee, Sarah Oh, Tiffany Guo, Simone Girgis, Celine Park, Simon Haroutounian, Leonid Kagan Jul 2024

Pharmacokinetic Modeling Of The Effect Of Tariquidar On Ondansetron Disposition Into The Central Nervous System, Manting Chiang, Hyunmoon Back, Jong Bong Lee, Sarah Oh, Tiffany Guo, Simone Girgis, Celine Park, Simon Haroutounian, Leonid Kagan

2020-Current year OA Pubs

PURPOSE: Serotonin (5-HT

METHODS: Ondansetron (10 mg/kg) and tariquidar (7.5 mg/kg) were administered intravenously, plasma and tissue samples were collected and analyzed by HPLC. A mathematical model with brain, spinal cord, cerebrospinal fluid and two systemic disposition compartments was developed to describe the data.

RESULTS: The results demonstrate that tariquidar at 7.5 mg/kg resulted in a complete inhibition of Pgp efflux of ondansetron in the brain and spinal cord. The compartmental model successfully captured pharmacokinetics of ondansetron in wild type and Pgp knockout (KO) animals receiving the drug alone or in wild type animals receiving the ondansetron and tariquidar combination. …


Time And Imagined Futures In Eastern African Art Forms, Alex Perullo Jul 2024

Time And Imagined Futures In Eastern African Art Forms, Alex Perullo

Politics, Law, and Society Faculty Journal Articles

This article introduces the NJAS special issue “Art and Imagined Futures in Eastern Africa”, edited by Alex Perullo, Claudia Böhme, and Christina Woolner, and has not been peer-reviewed. Artists in eastern Africa use songs, poems, fiction, cartoons, and other artistic forms to explore their lived experiences and future possibilities. Through their art they can envision alternatives to their current experiences, contest social and political problems, and reveal the dangers of complacency. They can also grapple with regret at missed opportunities or develop a sense of longing for a future that could or should have been had different decisions been made. …


Seagrass Ecosystem Recovery: Experimental Removal And Synthesis Of Disturbance Studies, Spencer J. Tassone, Carolyn J. Ewers Lewis, Karen J. Mcglathery, Michael L. Pace Jul 2024

Seagrass Ecosystem Recovery: Experimental Removal And Synthesis Of Disturbance Studies, Spencer J. Tassone, Carolyn J. Ewers Lewis, Karen J. Mcglathery, Michael L. Pace

Michigan Tech Publications

Net global losses of seagrasses have accelerated efforts to understand recovery from disturbances. Stressors causing disturbances (e.g., storms, heatwaves, boating) vary temporally and spatially within meadows potentially affecting recovery. To test differential recovery, we conducted a removal experiment at sites that differed in thermal stress for a temperate seagrass (Zostera marina). We also synthesized prior studies of seagrass recovery to assess general patterns. Seagrass shoots were removed from 28.3 m2 plots at edge and central sites of a meadow in South Bay, Virginia, USA. We hypothesized faster recovery for edge plots where greater oceanic exchange reduces thermal stress. Contrary to …


Echinacea For Cut Flower Production In Utah, Ali Harrison, Melanie Stock, Lorin Harrison, Amanda Pratt, Claudia Nischwitz, Nick Volesky Jul 2024

Echinacea For Cut Flower Production In Utah, Ali Harrison, Melanie Stock, Lorin Harrison, Amanda Pratt, Claudia Nischwitz, Nick Volesky

All Current Publications

Echinacea, commonly known as coneflower, is an easy-to-grow, low-maintenance cut flower crop. As a perennial, plants can be expected to last up to 5 years in production before replacement is needed. Known for delicately arching petals and strong stems, echinacea comes in a wide range of colors that lend a wildflower look to floral design. Seed heads are also popular and can be harvested for their rust-orange cone shape.


Extended-Release 7-Day Injectable Buprenorphine For Patients With Minimal To Mild Opioid Withdrawal., Gail D'Onofrio, Andrew A. Herring, Jeanmarie Perrone, Kathryn Hawk, Elizabeth A. Samuels, Ethan Cowan, Erik Anderson, Ryan Mccormack, Kristen Huntley, Patricia Owens, Shara Martel, Mark Schactman, Michelle R. Lofwall, Sharon L. Walsh, James Dziura, David A. Fiellin Jul 2024

Extended-Release 7-Day Injectable Buprenorphine For Patients With Minimal To Mild Opioid Withdrawal., Gail D'Onofrio, Andrew A. Herring, Jeanmarie Perrone, Kathryn Hawk, Elizabeth A. Samuels, Ethan Cowan, Erik Anderson, Ryan Mccormack, Kristen Huntley, Patricia Owens, Shara Martel, Mark Schactman, Michelle R. Lofwall, Sharon L. Walsh, James Dziura, David A. Fiellin

Behavioral Science Faculty Publications

IMPORTANCE: Buprenorphine is an effective yet underused treatment for opioid use disorder (OUD).

OBJECTIVE: To evaluate the feasibility (acceptability, tolerability, and safety) of 7-day injectable extended-release buprenorphine in patients with minimal to mild opioid withdrawal.

DESIGN, SETTING, AND PARTICIPANTS: This nonrandomized trial comprising 4 emergency departments in the Northeast, mid-Atlantic, and Pacific geographic areas of the US included adults aged 18 years or older with moderate to severe OUD and Clinical Opiate Withdrawal Scale (COWS) scores less than 8 (minimal to mild), in which scores range from 0 to 7, with higher scores indicating increasing withdrawal. Exclusion criteria included methadone-positive …


Sex Differences In Spontaneous Respiratory Recovery In Chronic Hemisection, Taylor C. Holmes, Nicole M. Popp, Carley F. Hintz, Isabell Dobrzycki, Carolyn J. Schmitz, Kaylyn A. Schwichtenberg, Elisa J. Gonzalez-Rothi, Christopher W. Sundberg, Kristi A. Streeter Jul 2024

Sex Differences In Spontaneous Respiratory Recovery In Chronic Hemisection, Taylor C. Holmes, Nicole M. Popp, Carley F. Hintz, Isabell Dobrzycki, Carolyn J. Schmitz, Kaylyn A. Schwichtenberg, Elisa J. Gonzalez-Rothi, Christopher W. Sundberg, Kristi A. Streeter

Physical Therapy Faculty Research and Publications

Respiratory deficits after C2 hemisection (C2Hx) have been well documented through single-sex investigations. Although ovarian sex hormones enable enhanced respiratory recovery observed in females 2 wk post-C2Hx, it remains unknown if sex impacts spontaneous respiratory recovery at chronic time points. We conducted a longitudinal study to provide a comprehensive sex-based characterization of respiratory neuromuscular recovery for 8 wk after C2Hx. We recorded ventilation and chronic diaphragm electromyography (EMG) output in awake, behaving animals, phrenic motor output in anesthetized animals, and performed diaphragm muscle histology in chronically injured male and female rodents. Our results show that females expressed a greater recovery …


Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler Jul 2024

Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler

Physical Therapy Faculty Research and Publications

The purpose was to explore quadriceps electromechanical function (quadriceps latency) during gait after anterior cruciate ligament injury as a predictor for radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Change in latency after preoperative physical therapy was also examined.

Methods

Quadriceps latency (time between peak knee moment and quadriceps electromyography) was calculated before preoperative physical therapy (2.4 [0.5–7.5] months after anterior cruciate ligament injury) and after preoperative physical therapy in 24 athletes. Participants were dichotomized into osteoarthritis (Kellgren and Lawrence grade ≥ 2) and non-osteoarthritis groups at 6-years. Forward selection logistic repression was performed using z-score normalized quadriceps latency …


Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand Jul 2024

Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand

Physical Therapy Faculty Research and Publications

Background

Few studies have examined changes in skeletal muscle physiology post-stroke. This study examined changes in tissue oxygen saturation (StO2) of the vastus lateralis (VL) muscle of stroke survivors and age-matched control participants during maximal and submaximal isometric contractions of the knee extensor muscles.

Objectives

We hypothesized that tissue oxygen desaturation (ΔStO2) during knee extensor muscle contractions would be less in the VL in the paretic vs. the non-paretic and control legs.

Methods

Ten chronic stroke survivors (>6 months post-stroke) with lower extremity muscle weakness and 10 age-matched controls completed this prospective cohort study. Maximum …


Preferential Crystallization Of (±)-Pinenyllithium·Tmeda, Alexander N. Erickson, Curtis Haltiwanger, Masoumeh Rahim, Charles M. Garner Jul 2024

Preferential Crystallization Of (±)-Pinenyllithium·Tmeda, Alexander N. Erickson, Curtis Haltiwanger, Masoumeh Rahim, Charles M. Garner

Chemistry Faculty Research and Publications

(±)-Pinenyllithium·TMEDA or (tetra­methyl­ethylenedi­amine-κ2N,N′)(η3-6,6-di­methyl-2-methylenebi­cyclo­[3.1.1]hept­yl)lithium, [Li(C10H15)(C6H16N2)], is readily pre­pared from β-pinene, butyl­lithium and TMEDA, and the racemic material pre­fer­entially crystallizes even from 96:4 (92% ee) mixtures of (−)- and (+)-β-pinene, respectively. The structure is monomeric, with the geminal-dimethyl bridge of the bicyclic structure shielding one face of the allyl system, restricting the lithium to the opposite face and preventing the Li–all­yl–Li aggregation observed with some other allyl­lithium systems. The symmetry of the allyl system, bond lengths, bond angles and out-of-plane deviations …


The Hidden Monetary State, Gabriel Rauterberg, Joshua Younger Jul 2024

The Hidden Monetary State, Gabriel Rauterberg, Joshua Younger

Faculty Scholarship

Money is a motley. While the state enjoys a monopoly on issuing new physical currency, a variety of instruments serve money-like roles in the financial system. The commercial banking system significantly augments the money supply through issuing deposits. Alongside it, a shadow banking system has also developed, offering a range of deposit substitutes.

This Article seeks to cast new light on the U.S. financial system by exploring how, over the course of the twentieth century, federal policymakers engaged in a series of distinct and largely uncoordinated monetary experiments. As we show through historical case studies, federal authorities designed, promoted, and …


Capitalism And The Challenge Of Inequality, Andrzej Rapaczynski Jul 2024

Capitalism And The Challenge Of Inequality, Andrzej Rapaczynski

Faculty Scholarship

Rapidly rising income and wealth inequality in the United States and other Western countries has been commonly identified as an inherent and nefarious feature of the capitalist system. In fact, however, rising inequality within the economically advanced countries has been accompanied by both a significant relative improvement of the economic and social position of the previously disadvantaged groups, such as women and ethnic minorities, and an unprecedented reduction of the inequalities between the people living in the advanced countries and the rest of the world. This change is largely due to the phenomenon of globalization that brought the advantages of …


The Prohibition Of Annexations And The Foundations Of Modern International Law, Ingrid Brunk, Monica Hakimi Jul 2024

The Prohibition Of Annexations And The Foundations Of Modern International Law, Ingrid Brunk, Monica Hakimi

Faculty Scholarship

The international legal norm that prohibits forcible annexations of territory is foundational to modern international law. It lies at the core of three projects that have been central to the enterprise: (1) to settle title to territory as the basis for establishing state authority; (2) to regulate the use of force across settled borders; and (3) to provide for people within settled borders collectively to determine their own fates. Prohibiting forcible annexations is integral to each of these projects independently, and by tying them together, has had a transformative effect on the legal system as a whole. However, its significance …


Parker Solar Probe Observations Of Energetic Particles In The Flank Of A Coronal Mass Ejection Close To The Sun, Nathan A. Schwadron, Stuart D. Bale, J Bonnell, A Case, M Shen, E R. Christian, C M S Cohen, A J. Davis, M I. Desai, K Goetz, J Giacalone, M E. Hill, J C. Kasper, K Korreck, D Larson, R Livi, T Lim, R A. Leske, O Malandraki, D Malaspina, W H. Matthaeus, D J. Mccomas, R L. Mcnutt, R A. Mewaldt, D G. Mitchell Jul 2024

Parker Solar Probe Observations Of Energetic Particles In The Flank Of A Coronal Mass Ejection Close To The Sun, Nathan A. Schwadron, Stuart D. Bale, J Bonnell, A Case, M Shen, E R. Christian, C M S Cohen, A J. Davis, M I. Desai, K Goetz, J Giacalone, M E. Hill, J C. Kasper, K Korreck, D Larson, R Livi, T Lim, R A. Leske, O Malandraki, D Malaspina, W H. Matthaeus, D J. Mccomas, R L. Mcnutt, R A. Mewaldt, D G. Mitchell

Faculty Publications

We present an event observed by Parker Solar Probe (PSP) at ∼0.2 au on 2022 March 2 in which imaging and in situ measurements coincide. During this event, PSP passed through structures on the flank of a streamer blowout coronal mass ejection (CME) including an isolated flux tube in front of the CME, a turbulent sheath, and the CME itself. Imaging observations and in situ helicity and principal variance signatures consistently show the presence of flux ropes internal to the CME. In both the sheath and the CME interval, the distributions are more isotropic, the spectra are softer, and the …


Persistent Behavior In Solar Energetic Particle Time Series, N V. Sarlis, G Livadiotis, D J. Mccomas, M E. Cuesta, L Y. Khoo, C M S Cohen, D G. Mitchell, Nathan A. Schwadron Jul 2024

Persistent Behavior In Solar Energetic Particle Time Series, N V. Sarlis, G Livadiotis, D J. Mccomas, M E. Cuesta, L Y. Khoo, C M S Cohen, D G. Mitchell, Nathan A. Schwadron

Faculty Publications

We investigate the long-term persistence of solar energetic particle (SEP) time series by means of four different methods: Hurst rescaled range R/S analysis, detrended fluctuation analysis, centered moving average analysis, and the fluctuation of natural time under the time reversal method. For these analyses, we use data sets from the Integrated Science Investigation of the Sun instrument suite on board NASA's Parker Solar Probe. Background systematic noise is modeled using cross-correlation analysis between different SEP energy channels and subtracted from the original data. The use of these four methods for deriving the time-series persistence allows us to (i) differentiate between …


An Ixpe-Led X-Ray Spectropolarimetric Campaign On The Soft State Of Cygnus X-1: X-Ray Polarimetric Evidence For Strong Gravitational Lensing, James F. Steiner, Edward Nathan, Kun Hu, Henric Krawczynski, Michal Dovčiak, Alexandra Veledina, Fabio Muleri, Jiri Svoboda, Kevin Alabarta, Maxime Parra, Yash Bhargava, Giorgio Matt, Juri Poutanen, Pierre-Olivier Petrucci, Allyn F. Tennant, M Cristina Baglio, Luca Baldini, Samuel Barnier, Sudip Bhattacharyya, Stefano Bianchi, Maimouna Brigitte, Mauricio Cabezas, Floriane Cangemi, Fiamma Capitanio, Jacob Casey, Nicole Rodriguez Cavero, Simone Castellano, Elisabetta Cavazzuti, Sohee Chun, Eugene Churazov, Enrico Costa, Niccolò Di Lalla, Alessandro Di Marco, Elise Egron, Elise Egron, Melissa Ewing, Sergio Fabiani, Javier A. García, David A. Green, Victoria Grinberg, Petr Hadrava, Adam Ingram, Philip Kaaret, Fabian Kislat, Takao Kitaguchi, Vadim Kravtsov, Brankica Kubátová, Fabio La Monaca, Luca Latronico, Vladislav Loktev, Christian Malacaria, Frédéric Marin, Andrea Marinucci, Olga Maryeva, Guglielmo Mastroserio, Tsunefumi Mizuno, Michela Negro, Nicola Omodei, Jakub Podgorný, John Rankin, Ajay Ratheesh, Lauren Rhodes, David M. Russell, Miroslav Šlechta, Paolo Soffitta, Sean Spooner, Valery Suleimanov, Francesco Tombesi, Sergei A. Trushkin, Martin C. Weisskopf, Silvia Zane, Andrzej A. Zdziarski, Sixuan Zhang, Wenda Zhang, Menglei Zhou, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Chien-Ting Chen, Stefano Ciprini, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Jeffery J. Kolodziejczak, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Chi-Yung Ng, Stephen L. O'Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Kinwah Wu, Fei Xie Jul 2024

An Ixpe-Led X-Ray Spectropolarimetric Campaign On The Soft State Of Cygnus X-1: X-Ray Polarimetric Evidence For Strong Gravitational Lensing, James F. Steiner, Edward Nathan, Kun Hu, Henric Krawczynski, Michal Dovčiak, Alexandra Veledina, Fabio Muleri, Jiri Svoboda, Kevin Alabarta, Maxime Parra, Yash Bhargava, Giorgio Matt, Juri Poutanen, Pierre-Olivier Petrucci, Allyn F. Tennant, M Cristina Baglio, Luca Baldini, Samuel Barnier, Sudip Bhattacharyya, Stefano Bianchi, Maimouna Brigitte, Mauricio Cabezas, Floriane Cangemi, Fiamma Capitanio, Jacob Casey, Nicole Rodriguez Cavero, Simone Castellano, Elisabetta Cavazzuti, Sohee Chun, Eugene Churazov, Enrico Costa, Niccolò Di Lalla, Alessandro Di Marco, Elise Egron, Elise Egron, Melissa Ewing, Sergio Fabiani, Javier A. García, David A. Green, Victoria Grinberg, Petr Hadrava, Adam Ingram, Philip Kaaret, Fabian Kislat, Takao Kitaguchi, Vadim Kravtsov, Brankica Kubátová, Fabio La Monaca, Luca Latronico, Vladislav Loktev, Christian Malacaria, Frédéric Marin, Andrea Marinucci, Olga Maryeva, Guglielmo Mastroserio, Tsunefumi Mizuno, Michela Negro, Nicola Omodei, Jakub Podgorný, John Rankin, Ajay Ratheesh, Lauren Rhodes, David M. Russell, Miroslav Šlechta, Paolo Soffitta, Sean Spooner, Valery Suleimanov, Francesco Tombesi, Sergei A. Trushkin, Martin C. Weisskopf, Silvia Zane, Andrzej A. Zdziarski, Sixuan Zhang, Wenda Zhang, Menglei Zhou, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Chien-Ting Chen, Stefano Ciprini, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Jeffery J. Kolodziejczak, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Chi-Yung Ng, Stephen L. O'Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Kinwah Wu, Fei Xie

Faculty Publications

We present the first X-ray spectropolarimetric results for Cygnus X-1 in its soft state from a campaign of five IXPE observations conducted during 2023 May–June. Companion multiwavelength data during the campaign are likewise shown. The 2–8 keV X-rays exhibit a net polarization degree PD = 1.99% ± 0.13% (68% confidence). The polarization signal is found to increase with energy across the Imaging X-ray Polarimetry Explorer’s (IXPE) 2–8 keV bandpass. The polarized X-rays exhibit an energy-independent polarization angle of PA = −25.°7 ± 1.°8 east of north (68% confidence). This is consistent with being aligned to Cyg X-1’s au-scale compact radio …


Interstellar Neutral Hydrogen In The Heliosphere: New Horizons Observations In The Context Of Models, P Swaczyna, M Bzowski, K Dialynas, L Dyke, F Fraternale, A Galli, J Heerikhuisen, M Z. Kornbleuth, D Koutroumpa, I Kowalska-Leszczyńska, M A. Kubiak, A T. Michael, H -R Müller, M Opher, Fatemeh Rahmanifard Jul 2024

Interstellar Neutral Hydrogen In The Heliosphere: New Horizons Observations In The Context Of Models, P Swaczyna, M Bzowski, K Dialynas, L Dyke, F Fraternale, A Galli, J Heerikhuisen, M Z. Kornbleuth, D Koutroumpa, I Kowalska-Leszczyńska, M A. Kubiak, A T. Michael, H -R Müller, M Opher, Fatemeh Rahmanifard

Faculty Publications

Interstellar neutral (ISN) hydrogen is the most abundant species in the outer heliosheath and the very local interstellar medium (VLISM). Charge-exchange collisions in the outer heliosheath result in filtration, reducing the ISN hydrogen density inside the heliosphere. Additionally, these atoms are intensively ionized close to the Sun, resulting in a substantial reduction of their density within a few astronomical units from the Sun. The products of this ionization—pickup ions (PUIs)—are detected by charged particle detectors. The Solar Wind Around Pluto instrument on New Horizons provides, for the first time, PUI observations from the distant heliosphere. We analyze the observations collected …