Digital Commons Network^™

Vitamin C Extraction From Whey Protein Concentrate, Sophia Garcia-Buenrostro, Mia Rheede, Owen Mcdougal

Idaho Conference on Undergraduate Research

With the growing public use of protein powders and dietary supplements to enhance nutrient intake, accurately quantifying vitamins in fortified foods is becoming increasingly important. Measuring vitamin C in whey protein concentrate (WPC) powder is essential for maintaining nutritional quality and meeting regulatory standards in food. Vitamin degradation over time complicates accurate product labeling and can pose health risks, making reliable methods to monitor vitamin content and predict the necessary overage to meet end-of-shelf-life claims essential. This study aimed to develop an extraction method for this water-soluble vitamin from WPC, using protein precipitation with methanol and hydrochloric acid. High-performance liquid …

Interactions Of Lysenin Channels With Sn2+ Ions, Emmanuel A. Vergelin, Shane Browen, Addison Hobson, Lizbeth Calvillo, Emma Rosiles

Idaho Conference on Undergraduate Research

Lysenin, a pore-forming toxin extracted from the red earthworm E. fetida, inserts large conductance channels in artificial and natural lipid membranes containing sphingomyelin. Based on prior reports showing that lysenin channels interact with many multivalent metals by employing a ligand-gated mechanism, we hypothesized that lysenin channels might similarly interact with Sn²⁺ ions in water-aqueous solutions. Our investigations were conducted on lysenin channels reconstituted in planar bilayer lipid membranes composed of Asolectin, Sphingomyelin, and Cholesterol and bathed by buffered electrolyte solutions. The electrical measurements were performed with an Axopatch 200B electrophysiology amplifier in a voltage clamp setting. The conductance …

Local Multivariate Calibration Method Utilizing Prism With Future Application In Virtual Reality, Nakiah Shanafelt, John H. Kalivas

Idaho Conference on Undergraduate Research

Within analytical chemistry, it is increasingly difficult to determine the best method to predict analyte values of target samples from expansive datasets. These datasets contain many different samples, each with unique underlying matrix effects. For a target sample to be predicted accurately, the source samples used to build a model must be both matrix effect (spectrally) matched and contain similar analyte values. To achieve this goal, an algorithm named local adaptive fusion regression (LAFR) was recently developed. This algorithm, while already effective, was modified to utilize a method of determining similarity called physicochemical responsive integrated similarity measure (PRISM). Using PRISM …

Effect Of Cholesterol On The Kinetics Of Electropores In Red Blood Cell Membranes, Michael Muench, Thorin Honcik, Quintyn Wilson, John Elliot, Sevio Stanton, Helen Wensel, Daniel Fologea

Idaho Conference on Undergraduate Research

The fluidity of cell membranes is a biophysical parameter with large implications on the functionality of cells in both health and disease. Adjustments to membrane fluidity modulates the interactions between membranes and drugs, the functionality of transporters and receptors, and cellular motility. The fluidity of the cell membrane has been extensively studied in respect to the above effects, but the influence of membrane fluidity on the dynamics of pore formation in membranes has not been intensely researched. To fill this gap in the literature, it was needed to investigate the kinetics of electro-induced pores with respect to transport of water …

This Isn't About You, Joseph Wargo

Idaho Conference on Undergraduate Research

The project "This Isn't About You" is an attempt to complete a film documentary about my life told in an unconventional way: using the second-person.

To accomplish this, I scripted out five scenes based on aspects of my life, which became the five parts the film is told in: Away, Self, Friend, Uncle, and Home. In these scenes I address the camera directly and speak in second-person, replacing "I" with "you".

After each narration scene, I follow with a set of interviews of friends and family, asking them each one question related to that part (e.g. For "Uncle" I asked …

Development Of A Wearable Shoulder Exoskeleton For Stroke Rehabilitation Using Series Wrapping Cams, Alex Stella

Idaho Conference on Undergraduate Research

Individuals with impairment from stroke are often unable to lift and support their impaired arm against gravity due to cortical damage in the brain and the development of abnormal muscle synergies in the control of their affected side. Existing devices for rehabilitation and upper extremity support are mounted to a wheelchair or other stationary platform, making them impractical during many non-stationary activities of daily living. This research presents a wearable, lightweight, passive exoskeleton that will support an individual’s impaired arm against gravity, allowing for an improved range of motion (ROM) by assisting the impaired arm to support its own weight …

A Tale Of Two Residues: Exploring Novel Hypokalemic Periodic Paralysis Sodium Channel Mutations K1126i And R1129q, Shanae Van Leuven, Fatima Sanchez, Sydnie Clark, James Groome

Idaho Conference on Undergraduate Research

A difference in membrane potential dictates the electrical signal across a cell membrane, and its dysfunction is observed in diseases of neural and muscle cells. Hypokalemic periodic paralysis is a hypoexcitable skeletal muscle disorder in which patients experience attacks of muscle paralysis. This state of paralysis is associated with mutations of the human voltage-gated sodium (Nav) channel. Two novel periodic paralysis mutants within the S4 segment of domain III in the channel, K1126I and R1129Q, have not yet been studied. Here, we determined the impact of these mutations on channel function using cut open oocyte voltage clamp (COVC) electrophysiology. To …

Assessing Barriers To Housing In Boise, Audrey Wilson, Ines Lopo, Izzie Miller, Kristi Spalding, Maddi Flint, Sarah Green, Sunny Smart

Idaho Conference on Undergraduate Research

The Housing Opportunities for All VIP service-learning course partnered with the City of Boise Housing and Community Development Division across two semesters, Fall of 2023 and Spring of 2024. This course was tasked with revising two surveys that the City of Boise distributes annually focused on local housing issues. During the Fall 2023 semester, students revised and redesigned the survey instruments and during the Spring 2024 semester, students tested those instruments and distributed them throughout the community.

Throughout this partnership, our students learned about survey design, distribution strategies, community engagement, and analyzing survey data. This partnership helped students gain a …

Understanding Children's Safety Through Parental Views Of Risks And Strategies, Kayla Ramirez, Letizia Maukar, Michael Wendell, Jerry Alan Fails, Jessi Boyer, Kendall House, John Ziker, Hollie Abele

Idaho Conference on Undergraduate Research

Children are introduced to technology when they are young, resulting in the need for parents to learn about child-interfacing technologies to ensure their children remain safe while using digital devices. In our research, we investigated parental perspectives of technology platforms and risks as well as how their strategic approaches to mitigate those risks vary based on how much they “trust” their children when using those devices. Our research was conducted using an online survey, initially analyzing data from a previously distributed survey of 99 families (with children ages 6-12), revising the survey instrument, and redistributing the survey to 100 additional …

Computational Study Of Protein Dynamics And Allostery Through Molecular Modeling And Machine Learning, Sian Xiao

Chemistry Theses and Dissertations

This thesis studies the complexities of protein dynamics and allostery, presenting methodologies that leverage combined computational approaches, including molecular modeling and machine learning, to investigate these phenomena.

Protein dynamics bridge conformational ensembles and their corresponding functional states. It further plays a critical role in a wide range of biological processes. Therefore, studying protein dynamics is essential for understanding how proteins fulfill their biological functions. Allostery plays a pivotal role in biological processes, acting as a fundamental mechanism through which proteins transmit signals and regulate their activity. Despite its critical importance in biology, the specific allosteric mechanisms governing most proteins remain …

Growing South Dakota (Summer 2024), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Hayengas endow department head of animal science
[Page] 4 Reese named Klingbeil Endowed Educator
[Page] 5 SDSU Rodeo at Nationals
[Page] 6 Nwadike leading Department of Dairy and Food Science
[Page] 8 Hansen serving as 2024 Hobo Day Grand Pooba
[Page] 10 The scoop on the Davis Dairy Plant
[Page] 14 Research shows value in change
[Page] 16 Legacy of 'Yellow Ore, Yellow Hair, Yellow Pine'
[Page] 20 SDSU beef team grows
[Page] 22 SDSU Extension supporting local foods movement
[Page] 24 Bolstering rural child care needs
[Page] 26 Feeding kids great food
[Page] 27 Education Abroad takes …

Quantifying And Classifying Streamflow Ensembles Using A Broad Range Of Metrics For An Evidence-Based Analysis: Colorado River Case Study, Homa Salehabadi, David G. Tarboton, Kevin G. Wheeler, Rebecca Smith, Sarah Baker

Outreach

Using the Colorado River Basin as a case study, this research article highlights the need for streamflow ensembles that accurately represent potential future conditions rather than solely relying on historical data. The comprehensive set of statistical metrics introduced can be used to evaluate and classify these streamflow ensembles. This evidence-based framework can inform water resource management in the face of uncertain conditions.

Nnlm Region 2 Y4 Kickoff, July 1, 2024, Network Of The National Library Of Medicine, Regional Medical Library 2

NNLM Region 2 Kickoffs

No abstract provided.

Vaccine-Sensitive Allocation - Another Divide To Divide Us?, Joelle Robertson-Preidler, Olivia Schuman

Faculty and Staff Publications

No abstract provided.

Performance And Environmental Assessment Of Biochar-Based Membranes Synthesized From Traditional And Eco-Friendly Solvents, Abelline Katusiime Fionah, Isaac Oluk, Laura Brady, Diana M. Byrne, Isabel Escobar

UK CARES Faculty Publications

Water contamination resulting from coal spills is one of the largest environmental problems affecting communities in the Appalachia Region of the United States. This coal slurry contains potentially toxic substances, such as hydrocarbons, heavy metals, and coal cleaning chemicals, and its leakage into water bodies (lakes, rivers, and aquifers) can lead to adverse health effects not only for freshwater bodies and plant life but also for humans. This study focused on two major experiments. The first experiment involved the use of biochar to create a biochar–polysulfone (BC-PSf) flat-sheet multifunctional membrane to remove organic contaminants, and the other major experiment compared …

Role Of Hospital Leadership In Pandemic Preparedness: Experience At A Tertiary Hospital In Kenya During The Covid-19 Pandemic, Lucy Wangari, William Macharia, Benjamin Wachira, Jemimah Kimeu, Boniface Mativa, Lukoye Atwoli

Emergency Medicine, East Africa

Introduction Pandemic preparedness refers to being ready for, responding to and recovering from public health crises, and is integral for health security. Hospital leadership is a critical building block of an effective healthcare system, providing policy, accountability and stewardship in a health crisis.

Objectives and methods We aimed to describe the leadership and governance structures put in place at the Aga Khan University Hospital, Nairobi, a private not-for-profit tertiary healthcare facility, following the COVID-19 pandemic. We reviewed over 200 hospital documents archived in the COVID-19 repository including those received from the Kenya Ministry of Health, emails, memos, bulletins, meeting minutes, …

Future Directions For Emergency Medical Services Development In Low- And Middle-Income Countries, Peter Delaney, Jon Moussally, Benjamin Wachira

Emergency Medicine, East Africa

The lack of prehospital care access in low- and middle-income countries is one of the greatest unmet needs and, therefore, one of the most urgent priorities in global health. Establishing emergency medical services in low- and middle-income countries poses significant challenges and complexities, requiring solutions tailored to prevailing conditions, informed by needs assessments, and adapted to meet local demands in a culturally appropriate and sustainable manner. In areas without existing emergency medical services, patients must rely on informal networks of untrained bystanders and community members to provide first aid and transport to definitive care. Since 2005, training lay first responders …

Usa Libraries Newsletter - July 2024, Paula Webb

USA Libraries Newsletter

Contents include:

• Archivist Daniel Shemwell Presents at Staff Summer Workshop 2024
• SELA 2024: Recharge in Rocket City
• INTO LIGHT Project Coming to University of South Alabama
• Frankenstein Coming to USA Libraries
• The World of Generative Artificial Intelligence Models and University Libraries: How It's Going So Far
• Micro Book Review
• Did You Know?

Exploring The Functional Significance Of A Yap1 Missense Variant Of Uncertain Significance In Caenorhabditis Elegans, Nathan Jones

Theses

Polycystic ovary syndrome (PCOS) is a complex disorder with various implications, such as polycystic ovaries, visceral obesity, and increased risk of cancer. YAP1 was recently identified as a gene of interest in the development of PCOS. Researchers have established that single nucleotide variants in YAP1 are likely to play a role in PCOS development. This project aims to provide insight into the potential impact of a YAP1 variant of uncertain significance (VUS). Studies in C. elegans have established yap-1 as a nematode ortholog for human YAP1. A YAP1 VUS was identified through ClinVar, YAP1 c.1015A>G (p.Asn339Asp). Evolutionary conservation …

Effects Of Simulated Climate Change On Native Southeastern Grassland Vegetation Using Open Top Chambers, Makaila Carpenter

Theses

The southeastern United States is a critical biodiversity hotspot once covered in prairie grassland ecosystems and now facing significant threats due to urbanization, habitat destruction, over-exploitation, biological invasions, pollution, and climate change. This study analyzes the response of Alabama’s native prairie ecosystem to climate change. We used open top chambers (OTCs) to simulate climate change-induced warming. We assessed the response of ecosystem function and structure to higher temperatures (1-3^oC). The indicators of ecosystem function included phenology, leaf surface area (LSA), specific leaf area (SLA), and aboveground and below net primary productivity (ANPP and BNPP respectively). Ecosystem structure was …

Effects Of Vitis Vinifera L. Seed Extract On Short-Term Memory Of Amyloid-Beta-Mediated Neurodegeneration In Transgenic Caenorhabditis Elegans, Elise Patrick

Theses

Alzheimer's disease (AD) is a neurodegenerative condition that is a common cause of dementia and a growing concern worldwide with no effective treatment or cure. Two pathological AD hallmarks include buildup of amyloid beta (Aβ) plaques and neurofibrillary tangles in the brain. Recent attention has turned to exploring natural products and compounds for AD symptom relief and treatment. Vitis vinifera grape seed extract (GSE) contains many beneficial substances. GSE has been tested in several animal models and has shown to improve memory and is even being examined in an AD treatment human clinical trial. In this study, the aim was …

Full Issue - Spring 2024 - Volume 111, Issue 1, Colby College

Colby Magazine

05. Building on Traditional Strengths in the Sciences, Colby Plans for ‘New Ways of Knowing’
14. A Place Where Anything is Possible
38. Embracing Unmastery
60. News AI for Everyone
64. ‘A Compass for the Field’
70. Class Notes
92. In Memoriam

Drone-Based Airborne Vlf-Em In Detecting Groundwater Contamination Due To Landfill Leachate, Chanho Park, Mine Dogan

Waldo Library Student Exhibits

Modern landfills follow a strict state and federal regulation on their location, design, operation and monitoring practices. One of the key focus in the regulations is in terms of leachate. While the exact composition of the leachates depends on various factors such as waste composition and degradation processes, in general they contain groups of dissolved organic matter, inorganic cations and heavy metals.

Very Low Frequency-Electromagnetic (VLF-EM) has been widely used for delineating leachate plume direction and boundaries. Previous studies using VLF-EM were carried out as on-ground measurements due to limitations in technologies. With the advancements in Unmanned Airborne Systems (UAS), …

The Impact Of Rural-Urban Migration On The Pension System In China, Boxia Xu

Waldo Library Student Exhibits

This research examines the influence of rural-urban migration on China's pension insurance system. China's urban-rural structure is rapidly transforming. Consequently, the migration of populations from rural to urban areas has significantly impacted the social security system, especially the pension insurance system. This study analyzes data from 141,456 respondents using a binomial logistic regression model to explore the key factors influencing individual participation in pension insurance for the urban working group. The results indicate that education level, income, employment status, workplace, and residential area significantly affect pension insurance participation. Notably, an increase in education and income levels, as well as residing …

I’M Not A Writer, I’M An Alpaca: Preferences And Perspectives Of Emergent Writers, Shaya Helbig

Waldo Library Student Exhibits

This case study explored preschool children’s perspectives and preferences in writing. While the voices of children are valued in research, often it is the voice of the adult researcher that emerges through their interpretations of the children’s perspectives (Harcourt & Sargent, 2011). In addition, research focusing on children’s interest in writing is limited (Rowe & Neitzel, 2010). The focal study held three focus group sessions, framed by Write, Draw, Show, and Tell (Noonan et al., 2016) with four preschool-aged children in order to better understand their preferences in writing materials, and their perceptions and understanding of writing. Data sources included …

Measuring Uk Libraries User Satisfaction: Ukl Libqual+ 2024 Results, Julene L. Jones

Library Presentations

Presentation based on the University of Kentucky's 2024 LibQUAL+ implementation

Ricky Kamdem-Ouaffo V. Colgate Palmolive Co

2024 Decisions

USDC for the District of New Jersey

Brian Taylor V. C. Carter

2024 Decisions

USDC for the District of New Jersey

Dawn Cutillo V. David Cutillo

2024 Decisions

USDC for the Eastern District of Pennsylvania

Luis Diaz Almanzar V. Attorney General United States

2024 Decisions

Agency