Digital Commons Network^™

Nature Restoration And Rewilding, Andrew N. Rowan

WellBeing News

The European Union's new law provides a clear example of how controversial the restoration of nature or rewilding can be.

Australian Cats: Making A Difference, Andrew N. Rowan

WellBeing News

This article documents the positive impacts of humane urban cat management.

Climate, Health, And Dengue, Andrew N. Rowan, Kathleen Rowan

WellBeing News

Climate change will create more challenges for public health.

Superphenomena For Arbitrary Quantum Observables, Andrew N. Jordan, Yakir Aharonov, Daniele C. Struppa, Fabrizio Colombo, Irene Sabadini, Tomer Shushi, Jeff Tollaksen, John C. Howell, A. Nick Vamivakas

Mathematics, Physics, and Computer Science Faculty Articles and Research

Superoscillations occur when a globally band-limited function locally oscillates faster than its highest Fourier component. We generalize this effect to arbitrary quantum-mechanical operators as a weak value, where the preselected state is a superposition of eigenstates of the operator with eigenvalues bounded to a range, and the postselection state is a local position. Superbehavior of this operator occurs whenever the operator's weak value exceeds its eigenvalue bound. We give illustrative examples of this effect for total angular momentum and energy. In the latter case, we demonstrate a sequence of harmonic oscillator potentials where a finite-energy state converges everywhere on the …

Adopting Oer Course Materials: Instructor Experiences, Jenny Ceciliano

Dissertations and Theses

Traditional commercial textbooks used in postsecondary courses are often problematic due to their rigidity, tendency to mirror the dominant culture, and the substantial cost imposed upon students. Although replacing these texts with open educational resources (OER) can facilitate more equitable and inclusive pedagogical practices while removing a significant expense, there has been insufficient research surrounding instructors' experience of transitioning from a commercial textbook to OER course materials. Through semi-structured interviews with nine postsecondary instructors who teach with OER course materials, this basic qualitative study explores the experience of that transition. The findings indicate that adopting OER is a challenging and …

2024 Beyond Lectures Micro-Immune Battles Evaluation. Project Dataset., Michael Dillon, James Edwards, Alexandra Hughes, Holly Stephenson

Faculty of Health Datasets

Teaching the complex interactions between hosts and pathogens is a fundamental yet pedagogically challenging aspect of medical education. The intricate mechanisms of the immune system can pose significant barriers to students’ understanding of infectious disease diagnosis and treatment. To address this, we used a digital whiteboard platform to design a card-based competitive game called Micro-Immune Battles, aimed at more actively engaging students with microbiology and immunology concepts. Dataset Description: This dataset consists of an Excel spreadsheet that collates anonymised qualitative and quantitative survey responses evaluating the Micro-immune battles game. The spreadsheet contains two tabs corresponding to two separate surveys: (1) …

Prefatory Matter

Richmond Public Interest Law Review

No abstract provided.

Letter From The Editor, Courtney Squires

Richmond Public Interest Law Review

No abstract provided.

Free To Learn: Protecting Muslim Students In Public Schools, Case Precedent And Social Theory In The Fight To Protect Their Rights, Harold Hinds

Richmond Public Interest Law Review

In the aftermath of 9/11, anti-Muslim American sentiments surged. With social tensions escalating as a result of the ongoing Israel-Gaza war and, what many feel is xenophobic rhetoric from high profile political figures, discrimination against Muslim Americans has further grown. Muslim youth in this country have experienced acute discrimination that has the potential to make school an uncomfortable and hostile place. This article explains the different ways in which Muslim American students experience discrimination and provides a roadmap for how administrators, activists, attorneys, and advocates can use the long and storied history of American civil rights litigation to protect the …

Agricultural Labor Trafficking In The U.S.: An Exchange Network Analysis, Gary J. Kowaluk

Richmond Public Interest Law Review

Labor trafficking occurs when individuals are forced to work by force, fraud, or coercion. In the United States, agricultural labor trafficking is both widespread and underreported. It is often carried out by farm labor subcontractors, who conduct the labor trafficking on behalf of U.S. companies. Labor trafficking in U.S. agriculture continues year after year, as trafficked immigrant workers fear being further punished if they attempt to redress their workplace grievances. The H-2A visa system is designed to protect workers from labor trafficking abuses, but the system is ineffective and in need of reform. To learn more about agricultural labor trafficking …

From Community Science To Community Justice: Protecting Data Usability In Community Air Quality Monitoring Networks, Marley Manjarrez

Richmond Public Interest Law Review

Community science holds significant promise for empowering communities to address air quality disparities and advocate for policy change. However, the usability and legal defensibility of community-collected data pose significant challenges. This article argues that with the help of low-cost tools such as air quality monitors, community members can take an active role in combating the disproportionate distribution of air pollutants hidden by our current regulatory scheme. By examining the regulatory frameworks under the Clean Air Act and opportunities for procedural justice at federal, state, and local levels, the article identifies pathways for incorporating community-collected data into air quality regulation and …

Ai-Assisted Segmentation Tool For Brain Tumor Mr Image Analysis, Myungeun Lee, Jong Hyo Kim, Wookjin Choi, Ki Hong Lee

Department of Radiation Oncology Faculty Papers

TumorPrism3D software was developed to segment brain tumors with a straightforward and user-friendly graphical interface applied to two- and three-dimensional brain magnetic resonance (MR) images. The MR images of 185 patients (103 males, 82 females) with glioblastoma multiforme were downloaded from The Cancer Imaging Archive (TCIA) to test the tumor segmentation performance of this software. Regions of interest (ROIs) corresponding to contrast-enhancing lesions, necrotic portions, and non-enhancing T2 high signal intensity components were segmented for each tumor. TumorPrism3D demonstrated high accuracy in segmenting all three tumor components in cases of glioblastoma multiforme. They achieved a better Dice similarity coefficient (DSC) …

Exploring Equity, Diversity, And Inclusion In Computer Science Undergraduate Curricula, Ouldooz Baghban Karimi, Giulia Toti, Fiona Mcneill, Alice Gao, Rutwa Engineer, Shanon Reckinger, Peggy Lindner, Jinyoung Hur, Rebecca Robinson, Anna Sollazzo, Richard Wicentowski

Engineering Management and Systems Engineering Faculty Research & Creative Works

One of the less explored approaches to foster equity, diversity, and inclusion (EDI) in Computer Science (CS) is through changes to the curriculum. Despite sporadic work on the adoption of Culturally Responsive Computing (CRC) and Universal Design for Learning (UDL), the inclusion of equity-minded courses, or modifications on specific elements of the curriculum such as introductory programming courses, there has never been a wide exploration or adoption of a successful equity-minded undergraduate CS curriculum. In this work, we explore undergraduate CS curricula, with a special focus on upper division, lower division, and service courses (courses offered to non-CS students). For …

Draft Genome Assemblies Of Three Klebsiella Grimontii Strains Isolated From Catheterized Urine Samples From The Same Male Participant Over The Course Of 6 Months, Helen Appleberry, Warwick Price, Lorenzo Roque, Evelyn Umana, Alan J. Wolfe, Catherine Putonti, Alex Kula

Biology: Faculty Publications and Other Works

Klebsiella grimontii is a newly identified species within the Klebsiella oxytoca complex. Here, we present the draft genome sequence of three K. grimontii strains that were isolated from catheterized urine samples collected from a participant in a longitudinal study over ~6 months.

Board Of Directors Meeting Minutes (July 8, 2024), Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on July 8, 2024.

Cell And Molecular Mechanisms Of Plasticity And Injury Associated With Spreading Depolarization, Jordan E. Weisend

Biomedical Sciences ETDs

Spreading depolarization (SD) is now established as a critical event contributing to the expansion of acute brain injuries. In areas with insufficient access to metabolites, SD results in episodic glutamate accumulation and NMDA receptor over-activation. Intriguingly, in areas with sufficient access to metabolites SD can result in synaptic strengthening, together suggesting SD consequences may vary widely based on metabolic context. Utilizing acute murine brain slices, this dissertation sought to interrogate the cell and molecular mechanisms of SD induced detriment and revitalization. We describe evidence that the primary NMDAR subtype involved in SD is GluN2A-containing NMDARs, and when targeted during SD …

Oregon State Rank Assessment For Mountain Townsendia (Townsendia Montana), Lindsey K. Wise

Institute for Natural Resources Publications

Oregon state conservation status assessment for mountain townsendia (Townsendia montana) using NatureServe methodology, 2024.

Identification And Characterization Of Intrinsically Disordered Protein Regions, Guy Wayne Dayhoff Ii

USF Tampa Graduate Theses and Dissertations

This dissertation investigates protein intrinsic disorder and intrinsically disordered protein regions (IDPRs) through the development and application of advanced computational and experimental techniques. Chapter 1 provides an introduction to protein intrinsic disorder, outlining the historical context and fundamental concepts that highlight the importance of intrinsically disordered proteins (IDPs) and IDPRs in various biological processes. Chapter 2 focuses on the rapid prediction and analysis of protein intrinsic disorder. We introduce RIDAO (Rapid Intrinsic Disorder Analysis Online), a high-efficiency web-based tool that integrates multiple disorder predictors. RIDAO significantly outperforms existing predictors in computational efficiency, making it suitable for large-scale proteomic studies. We …

Fundamental Limits In Measuring The Anisotropic Rotational Diffusion Of Single Molecules, Weiyan Zhou, Tingting Wu, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Many biophysical techniques, such as single-molecule fluorescence correlation spectroscopy, Förster resonance energy transfer, and fluorescence anisotropy, measure the translation and rotation of biomolecules to quantify molecular processes at the nanoscale. These methods often simplify data analysis by assuming isotropic rotational diffusion, e.g., that molecules wobble within a circular cone. This simplification ignores the anisotropy present in many biological contexts that may cause molecules to exhibit different degrees of diffusion in different directions. Here, we loosen this assumption and establish a theoretical framework for describing and measuring anisotropic rotational diffusion using fluorescence imaging. We show that anisotropic wobble is directly quantified …

Recoil-Order And Radiative Corrections To The Acorn Experiment, F. E. Wietfeldt, W. A. Byron, B. Collett, M. S. Dewey, T. R. Gentile, F. Glück, M. T. Hassan, G. L. Jones, Alexander Komives, J. S. Nico, E. J. Stephenson

Physics & Astronomy Faculty publications

The aCORN experiment measures the electron-antineutrino correlation 𝑎 coefficient in free neutron decay. We update the previous aCORN results [G. Darius et al., Phys. Rev. Lett. 119, 042502 (2017) and M. T. Hassan et al., Phys. Rev. C 103, 045502 (2021)] to include radiative and recoil corrections to first order, and discuss a key issue in the comparison of results from different 𝑎-coefficient experimental methods when these effects are considered. The corrected combined result is ‾𝑎=−0.10779±0.00125⁢(stat)±0.00134⁢(sys), averaged over the full Fermi neutron beta spectrum. The corresponding corrected result for the ratio of weak coupling constants 𝜆=𝐺𝐴/𝐺𝑉 is …

The Prevalence Of Candida Albicans And Malassezia Globosa In Preschool Children With Severe Early Childhood Caries: A Case-Control Study, Vanessa C.W. Man, Prasanna Neelakantan, Cynthia K.Y. Yiu

Pacific Faculty Work

Background: This cross-sectional study aimed to identify the prevalence of Candida albicans and Malassezia globosa in children with severe early childhood caries and caries-free children in Hong Kong. Methods: This study first recruited a total of 80 children aged between 48 and 72 months old, 40 children with severe early childhood caries, and 40 caries-free children. The children were then further divided into four groups, with 20 children in each group: Group 1: Severe early childhood caries—C. albicans, Group 2: Severe early childhood caries—M. globosa, Group 3: Caries-free—C. albicans and Group 4: Caries-free—M. globosa. Saliva, plaque, and caries lesion samples …

Spinal Movement Disorders In Nmosd, Mogad, And Idiopathic Transverse Myelitis: A Prospective Observational Study, Hesham Abboud, Rongyi Sun, Nikhil Modak, Mohamed Elkasaby, Alexander Wang

Faculty Scholarship

Background: Retrospective studies suggest that spinal movement disorders, especially tonic spasms, are prevalent in NMOSD. However, there have been no prospective studies evaluating spinal movement disorders in NMOSD, MOGAD, and idiopathic transverse myelitis (ITM). Methods: Patients referred to a tertiary neuroimmunology clinic for spinal cord demyelination (excluding MS) were evaluated. All patients answered a movement disorders survey and underwent a movement disorder-focused exam. Movement disorders were compared among patients with NMOSD with and without AQP4-IgG, MOGAD, and ITM. Patients with and without involuntary movements were also compared to identify predictors of spinal movement disorders. Results: Sixty-three patients were evaluated from …

Contributions Of Brain Microstructures And Metabolism To Visual Field Loss Patterns In Glaucoma Using Archetypal And Information Gain Analyses, Yueyin Pang, Ji Won Bang, Anisha Kasi, Jeremy Li, Carlos Parra, Els Fieremans, Gadi Wollstein, Joel S. Schuman, Mengyu Wang, Kevin C Chan

Wills Eye Hospital Papers

PURPOSE: To investigate the contributions of the microstructural and metabolic brain environment to glaucoma and their association with visual field (VF) loss patterns by using advanced diffusion magnetic resonance imaging (dMRI), proton magnetic resonance spectroscopy (MRS), and clinical ophthalmic measures.

METHODS: Sixty-nine glaucoma and healthy subjects underwent dMRI and/or MRS at 3 Tesla. Ophthalmic data were collected from VF perimetry and optical coherence tomography. dMRI parameters of microstructural integrity in the optic radiation and MRS-derived neurochemical levels in the visual cortex were compared among early glaucoma, advanced glaucoma, and healthy controls. Multivariate regression was used to correlate neuroimaging metrics with …

Transformative Agreements: The Good, The Bad, And The Confusing, Camille Mccutcheon, Peggy Kain, Tracy M. Cole

Libraries Professional Work

SELA, Huntsville, AL , July 7-9, 2024​

Students Bypass The Syllabus To Utilize Alternate Lms Locations For Assignment Deadlines, Savannah Lopez, Allison Pham, Jeremy L. Hsu, Patricia A. Halpin

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The syllabus is a required document for all courses to provide students with course information, policies, and assignment deadlines. The goals of this study were to investigate students’ perception of the role of the syllabus, preferred location of assignment deadlines, and preferred style of receiving deadline notifications. Faculty (n = 14) and students (n = 324) from community colleges through professional schools were invited to participate and complete a survey. We used a mixed-method design of survey questions, and the results demonstrated that students defined a syllabus as both a contract and a learning tool and that it …

Multi-Scale Signaling And Tumor Evolution In High-Grade Gliomas, Jingxian Liu, Song Cao, Yize Li, Ilya Strunilin, Andrew Shinkle, Nataly Naser Al Deen, Wagma Caravan, Andrew Houston, Faria Anjum Simin, Matthew A Wyczalkowski, Liang-Bo Wang, Erik Storrs, Siqi Chen, Ritvik Illindala, Yuping D Li, Reyka G Jayasinghe, Austin N Southard-Smith, Yang E Li, Rita Jui-Hsien Lu, Feng Chen, Milan G Chheda, Li Ding, Et Al.

2020-Current year OA Pubs

Although genomic anomalies in glioblastoma (GBM) have been well studied for over a decade, its 5-year survival rate remains lower than 5%. We seek to expand the molecular landscape of high-grade glioma, composed of IDH-wildtype GBM and IDH-mutant grade 4 astrocytoma, by integrating proteomic, metabolomic, lipidomic, and post-translational modifications (PTMs) with genomic and transcriptomic measurements to uncover multi-scale regulatory interactions governing tumor development and evolution. Applying 14 proteogenomic and metabolomic platforms to 228 tumors (212 GBM and 16 grade 4 IDH-mutant astrocytoma), including 28 at recurrence, plus 18 normal brain samples and 14 brain metastases as comparators, reveals heterogeneous upstream …

New Artists Announced For Uab's Alys Stephens Center, Shannon Thomason

Browse All News

No abstract provided.

Gerontological Continuing Education Needs Of Nurses Employed In Nursing Facilities In North Carolina, Sandra J. Todd-Atkinson

Dissertations

The major purpose of this investigation was to determine the self perceived learning needs of nurses employed in nursing facilities. Questionnaires were utilized to gather these data from nurses employed in fourteen nursing facilities thus representing 10% of all nursing facilities in North Carolina. Nonparametric tests were utilized to analyze the differences in perceived needs and selected independent variables. The selected independent variables were respondents' ages, educational preparation, years of experience, years of experience in a nursing facility, size of the facility, and position held. Two research questions guided the study: (1) what are the specific areas of felt needs …

Intratumoral Immune Triads Are Required For Immunotherapy-Mediated Elimination Of Solid Tumors, Paul Zumbo, Asim Dave, Doron Betel, Sung Wook Kang, Hee-Jin Jang, Matthew D Hellmann, Bryan M Burt, Hyun-Sung Lee, Andrea Schietinger

Faculty, Staff and Students Publications

Tumor-specific CD8+ T cells are frequently dysfunctional and unable to halt tumor growth. We investigated whether tumor-specific CD4+ T cells can be enlisted to overcome CD8+ T cell dysfunction within tumors. We find that the spatial positioning and interactions of CD8+ and CD4+ T cells, but not their numbers, dictate anti-tumor responses in the context of adoptive T cell therapy as well as immune checkpoint blockade (ICB): CD4+ T cells must engage with CD8+ T cells on the same dendritic cell during the effector phase, forming a three-cell-type cluster (triad) to license CD8+ T cell cytotoxicity and cancer cell elimination. …

Multi-Scale Signaling And Tumor Evolution In High-Grade Gliomas, Marina A Gritsenko, Tung-Shing M Lih, Jennifer E Kyle, Tomer M Yaron-Barir, Zev A Binder, Yize Li, Ilya Strunilin, Yi-Ting Wang, Chia-Feng Tsai, Weiping Ma, Lijun Chen, Natalie M Clark, Andrew Shinkle, Nataly Naser Al Deen, Wagma Caravan, Andrew Houston, Faria Anjum Simin, Matthew A Wyczalkowski, Liang-Bo Wang, Erik Storrs, Siqi Chen, Ritvik Illindala, Yuping D Li, Reyka G Jayasinghe, Dmitry Rykunov, Sandra L Cottingham, Rosalie K Chu, Karl K Weitz, Ronald J Moore, Tyler Sagendorf, Vladislav A Petyuk, Michael Nestor, Lisa M Bramer, Kelly G Stratton, Athena A Schepmoes, Sneha P Couvillion, Josie Eder, Young-Mo Kim, Yuqian Gao, Thomas L Fillmore, Rui Zhao, Matthew E Monroe, Austin N Southard-Smith, Yang E Li, Rita Jui-Hsien Lu, Jared L Johnson, Maciej Wiznerowicz, Galen Hostetter, Chelsea J Newton, Karen A Ketchum, Ratna R Thangudu, Jill S Barnholtz-Sloan, Pei Wang, David Fenyö, Eunkyung An, Mathangi Thiagarajan, Ana I Robles, D R Mani, Richard D Smith, Eduard Porta-Pardo, Lewis C Cantley, Antonio Iavarone, Feng Chen, Mehdi Mesri, Maclean P Nasrallah, Hui Zhang, Adam C Resnick, Milan G Chheda, Karin D Rodland, Tao Liu, Li Ding, Philadelphia Coalition For A Cure, Clinical Proteomic Tumor Analysis Consortium

Faculty, Staff and Students Publications

Although genomic anomalies in glioblastoma (GBM) have been well studied for over a decade, its 5-year survival rate remains lower than 5%. We seek to expand the molecular landscape of high-grade glioma, composed of IDH-wildtype GBM and IDH-mutant grade 4 astrocytoma, by integrating proteomic, metabolomic, lipidomic, and post-translational modifications (PTMs) with genomic and transcriptomic measurements to uncover multi-scale regulatory interactions governing tumor development and evolution. Applying 14 proteogenomic and metabolomic platforms to 228 tumors (212 GBM and 16 grade 4 IDH-mutant astrocytoma), including 28 at recurrence, plus 18 normal brain samples and 14 brain metastases as comparators, reveals heterogeneous upstream …