Digital Commons Network^™

Smokejumper Obituary: Clark, Donald Montgomery (Mccall 1952), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Clearman, Richard V. “Dick” (Missoula 1952), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Dolato, Max C. (Grangeville 1952), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Verbeck, Howard C. (North Cascades 1951), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Raymond, Earl Warren (Missoula 1951), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Lungren, Edward Clarence “Ed” (Mccall 1951), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Thain, James J. (Missoula 1951), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Exploring Parent Engagement In School-Based Behavioral Health Programs, Tina Marie Wehner Hickman

Walden Dissertations and Doctoral Studies

It is important to address the concept of parental involvement in school-based mental health counseling in order to address the presence of mental health issues in students. In school-based mental health services, enlisting parent engagement in adolescent interventions can be difficult and can, therefore, inhibit positive adolescent mental health outcomes. This case study examined an educational organization in the southwestern United States to identify barriers inhibiting parent involvement in adolescent school-based mental health and to explore strategies to encourage parent engagement. The Baldrige performance excellence framework was utilized as a guide to inform an understanding of the organization’s mission, strategic …

The Discursive Representations Of Africanness And Blackness In Chinese Cyberspace : A Critical Discourse-Historical Analysis, Jiapei Gu

Lingnan Theses (MPhil & PhD)

Recent years have seen deepened Sino-African ties. However, unlike friendly rhetoric at the state level, racial issues at the individual level are becoming increasingly salient. This study aims to enrich our current understanding of racial issues in China by examining the digital discursive representations of Africanness and Blackness produced by Chinese Weibo users. It investigates three African/Black people-related racial occurrences in China from 2020 to 2021. Those include the release of the draft of the Permanent Residence Law for Foreigners in 2020, the Okonkwonwoye case, where Okonkwonwoye physically assaulted a nurse during quarantine in 2020, and the Abdulmatten murder case …

Associations Between Total, Free And Bioavailable 25-Hydroxyvitamin D Forms With Adiponectin And Irisin In Maternal-Neonatal Pairs At Birth From Greece, Tarek Ziad Arabi, Hana M.A. Fakhoury, Hani Tamim, Rene F. Chun, Martin Hewison, Fatme Alanouti, Stefan Pilz, Cedric Annweiler, Georgios Tzimagiorgis, Costas Haitoglou, Spyridon N. Karras

All Works

Background: Apart from the well-established skeletal effects, vitamin D has been explored as a secretagogue influencing various adipokines, including adiponectin and irisin. Recent evidence suggests that specific forms of 25-Hydroxyvitamin D (25(OHD), such as free and bioavailable 25(OH)D, may provide more accurate measurements of vitamin D status. The relationship between vitamin D status and serum irisin and adiponectin concentrations remains largely unexplored, particularly during pregnancy. Methods: We analyzed data from 67 healthy maternal-neonatal pairs from Northern Greece at birth. Biochemical and hormonal tests were conducted on each maternal-neonatal pair. The vitamin D forms were estimated using validated mathematical models. Subsequently, …

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Ascending Dose Study To Evaluate The Safety, Tolerability, Pharmacokinetics (Pk) And Pharmacodynamic (Pd) Effects Of Posiphen In Subjects With Early Alzheimer's Disease, Douglas Galasko, Martin R Farlow, Brendan P Lucey, Lawrence S Honig, Donald Elbert, Randall Bateman, Jeremiah Momper, Ronald G Thomas, Robert A Rissman, Judy Pa, Vahan Aslanyan, Archana Balasubramanian, Tim West, Maria Maccecchini, Howard H Feldman

2020-Current year OA Pubs

BACKGROUND: Amyloid beta protein (Aβ) is a treatment target in Alzheimer's Disease (AD). Lowering production of its parent protein, APP, has benefits in preclinical models. Posiphen, an orally administered small molecule, binds to an iron-responsive element in APP mRNA and decreases translation of APP and Aβ. To augment human data for Posiphen, we evaluated safety, tolerability and pharmacokinetic and pharmacodynamic (PD) effects on Aβ metabolism using Stable Isotope Labeling Kinetic (SILK) analysis.

METHODS: Double-blind phase 1b randomized ascending dose clinical trial, at five sites, under an IRB-approved protocol. Participants with mild cognitive impairment or mild AD (Early AD) confirmed by …

Revisiting The Freshwater Imperative: Harnessing Team Science To Face Emerging Challenges To Freshwaters, Steven Sadro, Erin R. Hotchkiss, Kathryn L. Cottingham, Michael J. Vanni, Shannon Speir, Catherine M. O'Reilly

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Freshwater ecosystems face ever increasing environmental and ecological challenges. Recognition of those challenges is not new—over 30 years ago, a series of workshops convened to develop a research agenda (The Freshwater Imperative) to address those challenges. It was recognized that a critical component of solving the problems that freshwater ecosystems face would require greater interdisciplinary collaboration. Here, we discuss the context for the “Revisiting the Freshwater Imperative” workshop and describe how a small-workshop model can be used effectively to seed longer term collaborative partnerships in support of meeting the challenges freshwater ecosystems face. Some key recommendations include: (1) …

Ai Driven Analysis Of Mri To Measure Health And Disease Progression In Fshd, Lara Riem, Olivia Ducharme, Matthew Cousins, Xue Feng, Allison Kenney, Stephen J Tapscott, Jeff Statland, Dennis Shaw, Leo Wang, Michaela Walker, Leann Lewis, Michael A Jacobs, Doris G Leung, Seth D Friedman, Silvia S Blemker

Faculty, Staff and Student Publications

Facioscapulohumeral muscular dystrophy (FSHD) affects roughly 1 in 7500 individuals. While at the population level there is a general pattern of affected muscles, there is substantial heterogeneity in muscle expression across- and within-patients. There can also be substantial variation in the pattern of fat and water signal intensity within a single muscle. While quantifying individual muscles across their full length using magnetic resonance imaging (MRI) represents the optimal approach to follow disease progression and evaluate therapeutic response, the ability to automate this process has been limited. The goal of this work was to develop and optimize an artificial intelligence-based image …

Efficacy, Safety, And Tolerability Of Tivozanib In Heavily Pretreated Patients With Advanced Clear Cell Renal Cell Carcinoma, Andrew C Johns, Matthew T Campbell, Mamie Gao, Andrew W Hahn, Zita Lim, Jianjun Gao, Pavlos Msaouel, Nizar M Tannir

Faculty, Staff and Student Publications

BACKGROUND: Tivozanib has been approved as a third-line or later therapy for advanced renal cell carcinoma based on the TIVO-3 trial, which was conducted before immune checkpoint therapies (ICT), cabozantinib, and lenvatinib/everolimus became incorporated in the current sequential treatment paradigm for advanced clear cell RCC (ccRCC).

METHODS: We performed a retrospective study of patients with advanced ccRCC treated with tivozanib at MD Anderson Cancer Center during 6/2021-7/2023. A blinded radiologist assessed tumor response by RECIST v1.1. We assessed overall response rate (ORR), clinical benefit rate (CBR) [percentage of all treated patients who achieved radiologic response or stable disease (SD) for …

Lost In The Plot: Missing Visual Elements In Kaplan-Meier Plots Of Phase Iii Oncology Trials, Alexander D Sherry, Pavlos Msaouel, Ramez Kouzy, Joseph Abi Jaoude, Timothy A Lin, Clifton David Fuller, Ethan B Ludmir

Faculty, Staff and Student Publications

Missing visual elements (MVE) in Kaplan-Meier (KM) curves can misrepresent data, preclude curve reconstruction, and hamper transparency. This study evaluated KM plots of phase III oncology trials. MVE were defined as an incomplete y-axis range or missing number at risk table in a KM curve. Surrogate endpoint KM curves were additionally evaluated for complete interpretability, defined by (1) reporting the number of censored patients and (2) correspondence of the disease assessment interval with the number at risk interval. Among 641 trials enrolling 518 235 patients, 116 trials (18%) had MVE in KM curves. Industry sponsorship, larger trials, and more recently …

Reverse Phase Proteomic Array Profiling Of Asparagine Synthetase Expression In Newly Diagnosed Acute Myeloid Leukemia, Nisha Narayanan, Jennifer Marvin-Peek, Mohamad K Abouelnaaj, Dhabya Majid, Bofei Wang, Yihua Qiu, Hussein A Abbas

Faculty, Staff and Student Publications

Asparaginase-based therapy is a cornerstone in acute lymphoblastic leukemia (ALL) treatment, capitalizing on the methylation status of the asparagine synthetase (ASNS) gene, which renders ALL cells reliant on extracellular asparagine. Contrastingly, ASNS expression in acute myeloid leukemia (AML) has not been thoroughly investigated, despite studies suggesting that AML with chromosome 7/7q deletions might have reduced ASNS levels. Here, we leverage reverse phase protein arrays to measure ASNS expression in 810 AML patients and assess its impact on outcomes. We find that AML with inv(16) has the lowest overall ASNS expression. While AML with deletion 7/7q had ASNS levels slightly lower …

Dissociation Of Reading And Naming In Ventral Occipitotemporal Cortex

Faculty, Staff and Student Publications

Lesions in the language-dominant ventral occipitotemporal cortex (vOTC) can result in selective impairment of either reading or naming, resulting in alexia or anomia. Yet, functional imaging studies that show differential activation for naming and reading do not reveal activity exclusively tuned to one of these inputs. To resolve this dissonance in the functional architecture of the vOTC, we used focused stimulation to the vOTC in 49 adult patients during reading and naming, and generated a population-level, probabilistic map to evaluate if reading and naming are clearly dissociable within individuals. Language mapping (50 Hz, 2829 stimulations) was performed during passage reading …

On The Intellectual Horizons Of Social Realism: A Response To Barton, Jim Hordern

School of Law, Humanities and Social Sciences

This paper comments on the arguments made in ‘knowledge without disciplines: a critique of social realism’s disciplinary fixation’, authored by Keith Barton. It is suggested that Barton has not fully grasped how social realism views disciplines and curricula and that this reflects a wider tendency amongst commentators to overlook some of the thinking underpinning social realism. A different, more generous interpretation of social realism is outlined in respect of disciplinarity, the constitution of knowledge, the relationship between disciplines and subjects and the socio-epistemic formation that make knowledgeability possible. Social realism is seen as having already made a substantive impact, with …

Sustainability Considerations For End-Of-Life Fibre-Reinforced Plastic Boats, John Summerscales

School of Engineering, Computing and Mathematics

No abstract provided.

Process For Purification Of Abemaciclib, Anonymous

Defensive Publications Series

The present application relates to a process for purification of Abemaciclib.

The Spatial Pattern Analysis Of Settlements Area In Batusangkar City Tanah Datar Regency, Rery Novio, Sri Mariya, Bayu Wijayanto

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

The spatial distribution of populations and settlements is in line with connectivity and accessibility within a city area. Delineation of Batusangkar City exists in 3 sub-districts and 6 Nagari, causing settlement concentration in certain areas will form a certain distribution pattern and different settlement, the occurrence of diversity patterns distribution as a form of uneven population distribution. So that information is needed regarding changes in land use and patterns of settlement distribution concerning land use in urban planning. This study aims to discover the changes in area and distribution patterns of settlements. This research method is quantitative descriptive using secondary …

Spatial-Problem Based Learning (Spbl) Development (Preliminary Studies For Geography Learning), Waode Yunia Silviariza, Budi Handoyo

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Problem Based Learning (PBL) is one of the scientific learning models that is widely used by teachers to educate students about the subjects they teach. PBL is widely developed and applied in all fields of multidisciplinary science. Therefore, PBL in learning geography needs to be developed to fit the main characteristics of geography, namely the spatial approach. In geography learning, the Spatial Based Learning (SBL) model is often used. SBL is a model that can encourage students to think in space. Therefore, integrating PBL and SBL will create a new learning model that is more in line with the characteristics …

Mechanisation In Tea Plantation Driving Factors And Its Impact On Sustainable Environment, I Dewa Putu Eskasasnanda, Agung Wiradimadja

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Mechanization in tea plantation business is a phenomenon that is happening in Indonesia. The demand for tea products, the existence of land and tea plants that must be routinely maintained makes the managers of tea plantations have to find ways to manage tea plantations. Mechanization is a strategy taken by planters to cultivate land and maintain the amount of tea products when fewer workers are attracted to the tea plantation business. This paper will discuss the mechanization that occurs in the tea plantations of Serah Kencong, Blitar Regency. The focus of this paper is to explain the causes of mechanization …

Indonesia’S Maritime Strategy Facing The Kra Isthmus Canal Agenda, Fika Monika, M. Baiquni, M. Pramono Hadi

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This research will comprehensively analyze the Kra Isthmus Canal’s agenda and its possible impacts on Thailand and also to some other countries in ASEAN, specifically for Indonesia. By employing descriptive and qualitative methods, this study will investigate two types of paradigm through documentation and literature review from several studies in the past. The results are expected to encourage Indonesia to be more agile in adjusting steps to become the world's maritime fulcrum and also to sharpen the state sovereignty in sea policy.

Geography Education Research In Indonesia: Retrospect And Prospect, Dwi Angga Oktavianto

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Geography Education Research has been part of the Geography Development in Indonesia. So far there has been no research on the condition of Geography Education Research in Indonesia. This study aims to identify the development of Geographyby using qualitative research methods. Study literature is done by explores articles about Geography Education Research that sourced from journals produced by departments or faculties of Geography in Indonesia and have been indexed by SINTA. The results is that the most research in 1980’s with observation and writing narratives, concerning the condition of geography teaching in schools about teachers, curriculum, textbooks, and students who …

The Local Wisdom And Land Use Of Paddy Field In Sukarame Village, Cisolok Sub-District, Sukabumi Regency, Astrid Damayanti, Alisya Zhafira Hafiz, Aninda Ainun Mi’Raj, Muhammad Refiansyach Dwiyanto, Ravidania Auni

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Local wisdom is an understanding of a culture that has been inherited in a place from generation to generation by word-of-mouth. Indonesia, which still adheres to agriculture, always involves local wisdom in the use of their lands. Land-use is a visualization of the earth's surface cover, which results in a various earth formation, both natural and human-made. In the Village of Sukarame, there was a representative of Kasepuhan, which came from the Banten Kidul indigenous community, namely Kasepuhan Ciptagelar. This community still adheres to the traditional farming methods until now. The purpose of this study was to determine the relationship …

Potensi Pencemaran Air Tanah Bebas Pada Sebagian Kawasan Resapan Air Di Lereng Selatan Gunungapi Merapi, Sadewa Purba Sejati

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Penurunan kualitas air tanah bebas merupakan salah satu dampak yang dikhawatirkan akan muncul seiring dengan meningkatnya kepadatan penduduk sebagai konsekuensi dari pesatnya pembangunan yang terjadi pada sebagain kawasan resapan air primer. Kajian mengenai potensi pencemaran air tanah bebas perlu dilakukan sebagai alternatif pematauan kualitas air. Berdasarkan metode GOD, seluruh air tanah bebas di daerah penelitian berada dalam potensi pencemaran sangat tinggi. Keadaan tersebut terjadi karena faktor keadaan alami berupa jenis akuifer, material penyusun zona aerasi, dan kedalaman muka air tanah berpotensi mempermudah interaksi antara polutan atau sumber pencemar dengan air tanah bebas. Variasi potensi pencemaran air tanah diperoleh dengan mengembangkan …

Pengembangan Potensi Wilayah Di Kecamatan Samigaluh, Kabupaten Kulon Progo Melalui Pemetaan Potensi Wisata Berbasis Partisipasi, Mohammad Isnaini Sadali, Muhammad Arif Fahrudin Alfana, Khusnul Intan Dwi Fajar, Afwan Anantya Prianggoro, Afwan Anantya Prianggoro

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Tujuan penelitian ini adalah mengembangkan potensi wilayah di Kecamatan Samigaluh melalui pemetaan potensi wisata berbasis partisipasi masyarakat. Penelitian ini menggunakan metode penelitian kualitatif dan kuantitatif dengan data primer sebagai data utama. Metode GIS digunakan dalam membuat peta potensi wisata sesuai kaidah penyusunan peta partisipatif (participatory mapping). Teknik penggalian informasi dilakukan dengan wawancara stakeholder dan tokoh kunci (key person). Teknik triangulasi juga digunakan dalam penelitian ini untuk pengecekan informasi dengan melakukan identifikasi data yang diperoleh apakah bersifat tetap atau menunjukkan perubahan/variasi pada kondisi dan situasi berbeda. Hasil pemetaan potensi wisata berbasis partisipatif ditemukan 29 potensi wisata di Kecamatan Samigaluh. Kendala dan …

Hubungan Multiple Intelligences Pada Unsur Intrapersonal Dengan Ipk Mahasiswa Pendidikan Geografi Universitas Kanjuruhan Malang, Mustika Arif Jayanti, Achmad Maulana Malik Jamil

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This study aimed to know the correlation between intrapersonal intelligence and Geography Education students’ GPA from Kanjuruhan University from class 2015 of Kanjuruhan Malang University. This study used quantitative approach with the type of, correlational research. The independent variable was intrapersonal intelligence and the dependent one was students’ GPA. The subject for this study were Kanjuruhan University students of class 2015, Malang. The samples for this study ware 200 students. The result showseds that there were a positive correlation between intrapersonal intelligence and Geography Education students’ GPA from Kanjuruhan University of class 2015, Malang, shown by r hitung equals 0,990 …

Peningkatan Potensi Mitigasi Bencana Dengan Penguatan Kemampuan Literasi Kebencanaan Pada Masyarakat Kota Langsa, Ramdan Afrian, Zukya Rona Islami

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

This research aimed to enhance the ability of disaster information literacy for the community of Langsa. The method used in this research was an experiment. The method population of the research was the citizens of Gampong Java and Meurandeh totaled 11904 inhabitants. Research samples obtained by purposive sampling technique. Total sample of 15% of the population was 1786 people. The data were analyzed using a statistical test based on the average (mean) of each variable.The result shows that the process of improving information literacy of disaster brings an increase in familiarity with the community's preparedness against disasters and floods. It …