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Development Of A Simple And Accurate Polymerase Chain Reaction Screen For Human Papillomavirus In College Students, Emily Bishop, Owen Smith, Paul E. Richardson Jul 2024

Development Of A Simple And Accurate Polymerase Chain Reaction Screen For Human Papillomavirus In College Students, Emily Bishop, Owen Smith, Paul E. Richardson

Journal of the South Carolina Academy of Science

Human Papillomavirus (HPV) is, according to the CDC, the most common sexually transmitted infection (STI) with many infections developing in a person's late teens or early 20’s. HPV is a nonenveloped, relatively small, icosahedral DNA virus that infects squamous epithelial cells. This infection can happen in genital, anal, and oral cavities. 90% of these infections will self-clear in two years according to the CDC. Of the 10% of infections that do not clear in two years, they could develop into carcinomas later in life. The goal of this developmental research is to create a polymerase chain reaction (PCR) that can …


Physicist Is First Mississippian Named To National Physics Panel, Clara Turnage Jul 2024

Physicist Is First Mississippian Named To National Physics Panel, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The U.S. Department of Energy and the National Science Foundation have named University of Mississippi physics professor Breese Quinn to their High Energy Physics Advisory Panel.


Splenic Artery Embolization In The Treatment Of Blunt Splenic Injury: Single Level 1 Trauma Center Experience, Katelyn Gill, Sarah Aleman, Alexandra H. Fairchild, Bahri Üstünsöz, Dan Laney, Alison A. Smith, Hector Ferral Jul 2024

Splenic Artery Embolization In The Treatment Of Blunt Splenic Injury: Single Level 1 Trauma Center Experience, Katelyn Gill, Sarah Aleman, Alexandra H. Fairchild, Bahri Üstünsöz, Dan Laney, Alison A. Smith, Hector Ferral

School of Medicine Faculty Publications

PURPOSE: To describe the experience of a single level 1 trauma center in the management of blunt splenic injuries (BSI). METHODS: This is a retrospective study with Institutional Review Board approval. The medical records of 450 patients with BSI treated between January 2016 and December 2022 were reviewed. Seventy-two patients were treated with splenic artery embolization (SAE), met the study criteria, and were eligible for data analysis. Spleen injuries were graded in accordance with the American Association for the Surgery of Trauma Organ Injury Scale. Univariate data analysis was performed, with P < 0.05 considered statistically significant. RESULTS: The splenic salvage rate was 90.3% (n = 65/72). Baseline demographics were similar between the groups (P > 0.05). Distal embolization with Gelfoam had similar rates …


Mystical Luminosity Experience: An Initiation Of A Construct Grounded In Phenomenology, Jonathan Dinsmore Jul 2024

Mystical Luminosity Experience: An Initiation Of A Construct Grounded In Phenomenology, Jonathan Dinsmore

Psychological Science Faculty Publications and Presentations

Light of a divine or transcendent nature is widely revered in various religious and mystical traditions around the world, and luminosity with mystical qualities such as love, bliss, peace, and noetic realization is also frequently reported by contemporary experiencers. Despite being described as a profoundly significant, sacred, and transformative experience, mystical luminosity has received relatively little attention in modern scholarship and scientific study, and has only been examined empirically within isolated contexts, such as NDEs or contemplative practices. This study examines the phenomenology which binds mystical luminosity across various experiential contexts to construct a phenomenologically grounded theoretical model. A three-part …


Parg Is Essential For Polθ-Mediated Dna End-Joining By Removing Repressive Poly-Adp-Ribose Marks, Umeshkumar Vekariya, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Tatiana Kent, Katherine Sullivan-Reed, Jessica Atkins, Douglas Ralph, Margaret Nieborowska-Skorska, Anna-Mariya Kukuyan, Hsin-Yao Tang, Richard T. Pomerantz, Tomasz Skorski Jul 2024

Parg Is Essential For Polθ-Mediated Dna End-Joining By Removing Repressive Poly-Adp-Ribose Marks, Umeshkumar Vekariya, Leonid Minakhin, Gurushankar Chandramouly, Mrityunjay Tyagi, Tatiana Kent, Katherine Sullivan-Reed, Jessica Atkins, Douglas Ralph, Margaret Nieborowska-Skorska, Anna-Mariya Kukuyan, Hsin-Yao Tang, Richard T. Pomerantz, Tomasz Skorski

Department of Biochemistry and Molecular Biology Faculty Papers

DNA polymerase theta (Polθ)-mediated end-joining (TMEJ) repairs DNA double-strand breaks and confers resistance to genotoxic agents. How Polθ is regulated at the molecular level to exert TMEJ remains poorly characterized. We find that Polθ interacts with and is PARylated by PARP1 in a HPF1- independent manner. PARP1 recruits Polθ to the vicinity of DNA damage via PARylation dependent liquid demixing, however, PARylated Polθ cannot perform TMEJ due to its inability to bind DNA. PARG-mediated de-PARylation of Polθ reactivates its DNA binding and end-joining activities. Consistent with this, PARG is essential for TMEJ and the temporal recruitment of PARG to DNA …


Experimental Performance Evaluation Of A Thermoacoustic Stirling Engine With A Low-Cost Arduino-Based Acquisition System, Carmen Iniesta, Jordi Viñolas, Federico Prieto, José Luis Olazagoitia, Luis Soliverdi Jul 2024

Experimental Performance Evaluation Of A Thermoacoustic Stirling Engine With A Low-Cost Arduino-Based Acquisition System, Carmen Iniesta, Jordi Viñolas, Federico Prieto, José Luis Olazagoitia, Luis Soliverdi

Artículos científicos

Existing thermoacoustic dynamic measurement instrumentation is typically expensive and relies on proprietary designs, sensors, and acquisition equipment. However, this study presents a lowcost acquisition solution for sampling pressure and calculating instantaneous power measurements from a thermoacoustic engine using cost-effective sensors and control boards based on the Arduino platform. While the platform was designed for thermoacoustic engines with extra security for safe, high-speed data transfer, it could also suit other applications with similar needs. This study details the implementation of the sampling system and sensor arrangement, employing Python 3.10.2 algorithms based on the two-pressure sensor method to process and present the …


Lieutenant General Robert C. Richardson Jr.: Central Pacific Theater Army Commander For Admiral Chester W. Nimitz 1943–45, James D. Scudieri Jul 2024

Lieutenant General Robert C. Richardson Jr.: Central Pacific Theater Army Commander For Admiral Chester W. Nimitz 1943–45, James D. Scudieri

Books, Monographs & Collaborative Studies

This monograph analyzes Lieutenant General Robert C. Richardson Jr.’s service as de facto theater Army commander to Admiral Chester W. Nimitz from August 1943 to June 1945. It focuses on the theater-strategic level when Richardson led US Army Forces in Central Pacific Area and US Army Forces, Pacific Ocean Areas. This study highlights the context of Richardson’s operating environment beginning with prewar plans, the realities of early wartime defeats, and the state of joint operating procedures. It assesses Richardson’s accomplishments in exercising Landpower in the Pacific, across the entire range of today’s Army war-fighting and Joint functions and discusses the …


Hydrogen Adsorption On Ordered And Disordered Pt-Fe And Pt-Co Alloys, Andrew Okafor, William A. Shelton, Ye Xu Jul 2024

Hydrogen Adsorption On Ordered And Disordered Pt-Fe And Pt-Co Alloys, Andrew Okafor, William A. Shelton, Ye Xu

Faculty Publications

The bulk properties and surface chemical reactivity of compositionally disordered Pt-Fe and Pt-Co alloys in the fcc A1 phase have been investigated theoretically in comparison to the ordered alloys of the same compositions. The results are analyzed together with our previously reported findings for Pt-Ni. Nonlinear variation is observed in lattice constant, d band center, magnetic moment, and hydrogen adsorption energy across the composition range (0-100 atomic % of Pt, xPt). The Pt 5d states are strongly perturbed by the 3d states of the base metals, leading to notable density of states above the Fermi level and residual magnetic moments …


The Symbiosis Of Volunteerism: A Story Of One Academic Library Welcoming Volunteers, Shan Martinez Jul 2024

The Symbiosis Of Volunteerism: A Story Of One Academic Library Welcoming Volunteers, Shan Martinez

The Christian Librarian

Although public and school libraries, as well as many non-profit organizations regularly utilize volunteers, academic libraries are less likely to welcome them. This article describes the variety of volunteers received at Brown Library of Abilene Christian University and the tasks that they perform. It also presents a discussion of the motivation to accept volunteers, perhaps a faith practice.


Older Adult With Transplanted Kidney Failure From Ureteral Obstruction Within A Hernia, Joel Glotfelty, Hannah Grainger, Christina Shenvi Jul 2024

Older Adult With Transplanted Kidney Failure From Ureteral Obstruction Within A Hernia, Joel Glotfelty, Hannah Grainger, Christina Shenvi

Journal of Geriatric Emergency Medicine

Case Presentation

A 65-year-old male with a history of hypertension, hyperlipidemia, gout, and end-stage renal disease, who had undergone renal transplantation 12 years previously, with a baseline creatinine of 4.80 mg/dL presented to the Emergency Department (ED) due to progressively worsening right lower quadrant abdominal pain. He continued to produce urine and initially attributed his symptoms to gas or constipation. His home medications included losartan, pravastatin, tamsulosin, allpurinol, cyclosporine, mycophenylate, and prednisone. On examination in the ED, he had a bulge in the right inguinal area and right lower quadrant tenderness. His initial laboratory evaluation showed a creatinine of 14.24 …


Und Leads Implementation Team Meeting Agenda — July 11, 2024, University Of North Dakota Jul 2024

Und Leads Implementation Team Meeting Agenda — July 11, 2024, University Of North Dakota

LEADS Implementation Documents

Agenda for the July 11, 2024 meeting of the UND LEADS Implementation Team. The agenda includes subgroup reports and discussion of the UND LEADS Implementation Annual Report.


Annual Comprehensive Financial Report, Nashville And Davidson County, Tennessee For The Year Ended June 30, 2023, Davidson County (Tenn.). Department Of Finance. Jul 2024

Annual Comprehensive Financial Report, Nashville And Davidson County, Tennessee For The Year Ended June 30, 2023, Davidson County (Tenn.). Department Of Finance.

Tennessee County Audit Reports

No abstract provided.


Oregon State Rank Assessment For Cusick's Camassia (Camassia Cusickii), Nora Dunkirk Jul 2024

Oregon State Rank Assessment For Cusick's Camassia (Camassia Cusickii), Nora Dunkirk

Institute for Natural Resources Publications

Oregon state conservation status assessment for Cusick's camassia (Camassia cusickii) using NatureServe methodology, 2024.


Improvements In Computational Techniques For Determining Ideal Class Groups And Class Numbers, Muhammed Rashad Erukulangara Jul 2024

Improvements In Computational Techniques For Determining Ideal Class Groups And Class Numbers, Muhammed Rashad Erukulangara

USF Tampa Graduate Theses and Dissertations

The ideal class group is a fundamental concept in algebraic number theory, providing insights into the structure and factorization properties of the ring of integers of a number field. It measures the extent to which unique factorization fails in the ring of integers. Efficiently computing the ideal class group is crucial for exploring unproved heuristics in number theory and solving Diophantine equations. Additionally, the computation of the ideal class group has several cryptographic applications, such as schemes based on the Discrete Logarithm Problem (DLP), the computation of isogenies, and groups of unknown order. Despite its importance, much about the ideal …


Breaking The Sound Barrier: Strategies For Reducing The Educational Debt In Underserved School Bands, Alfonzo V. Kimbrough Jul 2024

Breaking The Sound Barrier: Strategies For Reducing The Educational Debt In Underserved School Bands, Alfonzo V. Kimbrough

USF Tampa Graduate Theses and Dissertations

The purpose of this multiple explanatory case study was to investigate the preparation of underserved school band programs for a Music Performance Assessment (MPA). Specifically, I examined racial, economic, and social inequalities, which are well documented in the research literature, and the related achievement gaps of underserved public school bands. Using Ladson-Billings’ four pillars of educational debt, a replication approach highlighted four cases as a small sample of the success rate of Title I school bands scoring a Superior at an MPA contest. I compared how contextual issues impacted the four band directors at these schools in preparations for their …


Regioselective Hydroamination Of Unactivated Olefins With Diazirine And Total Synthesis Of Nostodione A And Scytonemin, Qingyu Xing Jul 2024

Regioselective Hydroamination Of Unactivated Olefins With Diazirine And Total Synthesis Of Nostodione A And Scytonemin, Qingyu Xing

USF Tampa Graduate Theses and Dissertations

As an atom-economic way of carbon-nitrogen bond formation, hydroaminations are great tool for make amines, hydrazines, and other nitrogen-containing heterocycles. Specifically, radical hydroamination is a useful approach for functionalization of unactivated olefins, especially in sterically hindered environments. Diversification remains a challenge for radical hydroaminated products, since the nitrogen sources are carefully designed. In the first chapter of this dissertation, we report a highly diversifiable radical hydroamination reaction with diazirine as a nitrogen source and its potential applications in synthesis of several pharmaceutical interested compounds. Cobalt catalyzed regioselective hydroamination with diazirine shows wide function group tolerance, like phenyl thioether, ketones, esters, …


The Newgeneratortm Decentralized Wastewater Treatment System For Non-Sewered Sanitation: Technology Advancement Through Field Evaluation And Modeling, Hsiang-Yang Shyu Jul 2024

The Newgeneratortm Decentralized Wastewater Treatment System For Non-Sewered Sanitation: Technology Advancement Through Field Evaluation And Modeling, Hsiang-Yang Shyu

USF Tampa Graduate Theses and Dissertations

Non-sewered sanitation systems (NSSS) offer innovative solutions to sanitation challenges in areas lacking basic facilities, utilizing advanced treatment technologies for on-site water reuse. The NEWgenerator (NG), an advanced NSSS developed at the University of South Florida under the Bill & Melinda Gates Foundation’s Reinventing the Toilet Challenge, integrates an anaerobic membrane bioreactor (AnMBR), an ion exchange-based nutrient capture system (NCS), and an electrochlorinator for final disinfection. This study builds on previous field trials of the NG system, focusing on developing, evaluating, and optimizing its water reuse capabilities through field trials, system dynamics modeling, and advanced monitoring techniques.

In the first …


Disappearing Dysphagia And The Spontaneous Intraesophageal Hematoma, A Wayne Wheeler, Stephen Landreneau Jul 2024

Disappearing Dysphagia And The Spontaneous Intraesophageal Hematoma, A Wayne Wheeler, Stephen Landreneau

School of Medicine Faculty Publications

No abstract provided.


Cotton/Soybean Insect Newsletter, July 11, 2024, Jeremy K. Greene Jul 2024

Cotton/Soybean Insect Newsletter, July 11, 2024, Jeremy K. Greene

Clemson University Cotton/Soybean Insect Newsletter

No abstract provided.


Assessing Users’ Attention Classification Accuracy From Eeg Data, Gil Olenscki Neto Jul 2024

Assessing Users’ Attention Classification Accuracy From Eeg Data, Gil Olenscki Neto

USF Tampa Graduate Theses and Dissertations

Determining whether a person is attentive while performing a task is a key factor for understanding why they are achieving specific results. In addition, tracking these results is an important aspect to improving them. Quantified self is a field that consists of self-monitoring to gain a better understanding of your habits, health, and overall well-being. Examples of this method include tracking sleep patterns, daily steps, mood swings, and food intake.

This thesis aims to explore the potential of using an innovative self-quantification method that utilizes a mobile application that leverages alpha, beta, and theta waves to assess college students' attention …


Characterization Of The Apical Testis And Fusome Patterning In Drosophila Melanogaster, Drosophila Simulans, Drosophila Pseduoobscura, Drosophila Affinis, And Drosophila Sechellia, Crystal L. Calise Jul 2024

Characterization Of The Apical Testis And Fusome Patterning In Drosophila Melanogaster, Drosophila Simulans, Drosophila Pseduoobscura, Drosophila Affinis, And Drosophila Sechellia, Crystal L. Calise

Seton Hall University Dissertations and Theses (ETDs)

This study uses five different species across the family of Drosophila as a tool to compare the structures of the stem cell niche and fusome within the testes of these species. Three species from Drosophila melanogaster group, D. melanogaster, D. simulans and D. sechellia, and two species from D. obscura group, D. pseudoobscura and D. affinis were observed using confocal microscopy In addition to a general comparison of male reproductive system structure and anatomy, the species were also analyzed for the presence of Fasciclin-III and α-Spectrin. As expected, species from the D. melanogaster group had the same expression pattern for …


The Role Of Working Memory And Organizational Skills In Academic Functioning For Children With Attention-Deficit/Hyperactivity Disorder., Alissa M. Cole, Elizabeth S.M. Chan, Fatou Gaye, Sherelle L. Harmon, Michael J. Kofler Jul 2024

The Role Of Working Memory And Organizational Skills In Academic Functioning For Children With Attention-Deficit/Hyperactivity Disorder., Alissa M. Cole, Elizabeth S.M. Chan, Fatou Gaye, Sherelle L. Harmon, Michael J. Kofler

Department of Psychology Faculty Scholarship and Creative Works

Objective: Children with attention-deficit/hyperactivity disorder (ADHD) exhibit difficulties with organizational skills such as task planning, managing materials, and organizing activities that have downstream consequences on academic functioning. At the same time, deficits in working memory have been linked with both the organizational skills difficulties and academic underachievement and underperformance observed in children with ADHD and have been hypothesized to account for the link between organizational and academic functioning. However, the extent to which working memory and organizational skills independently versus jointly contribute to ADHD-related academic difficulties remains unclear. Method: The present study is the first to examine the unique and …


Embedding Direction Of Arrival And Antenna Beamforming Algorithms On Automated Software Defined Radio Platforms, Adrian J. Lewis Jul 2024

Embedding Direction Of Arrival And Antenna Beamforming Algorithms On Automated Software Defined Radio Platforms, Adrian J. Lewis

Electrical and Computer Engineering ETDs

Antenna arrays are an essential technology in the modern era in both communications and radar applications. The algorithms used for antenna arrays are beginning to be embedded in smart device applications to enable greater communication abilities. This thesis explores the idea of embedding direction of arrival and beamforming algorithms using a software defined radio platform. Specifically, the Multiple Signal Classification (MuSiC) algorithm and Minimum Variance Distortionless Response (MVDR) algorithm are combined. The combination of similar algorithms has the potential to be used in many internet of things applications to enable more dynamic communication ability.


Challenges Of Spatially Resolved Metabolism In Cancer Research, Andrew N. Lane, Richard M. Higashi, Teresa W-M Fan Jul 2024

Challenges Of Spatially Resolved Metabolism In Cancer Research, Andrew N. Lane, Richard M. Higashi, Teresa W-M Fan

Markey Cancer Center Faculty Publications

Stable isotope-resolved metabolomics comprises a critical set of technologies that can be applied to a wide variety of systems, from isolated cells to whole organisms, to define metabolic pathway usage and responses to perturbations such as drugs or mutations, as well as providing the basis for flux analysis. As the diversity of stable isotope-enriched compounds is very high, and with newer approaches to multiplexing, the coverage of metabolism is now very extensive. However, as the complexity of the model increases, including more kinds of interacting cell types and interorgan communication, the analytical complexity also increases. Further, as studies move further …


Ucf Libraries 2024 Faculty Research Showcase, Michael Furlong, David Benjamin, Renee Cole Montgomery, Chereeka Garner, Andy Todd, Peggy L. Nuhn, Jeanne Piascik, Tina H. Buck, Sara Duff, Sai Deng Jul 2024

Ucf Libraries 2024 Faculty Research Showcase, Michael Furlong, David Benjamin, Renee Cole Montgomery, Chereeka Garner, Andy Todd, Peggy L. Nuhn, Jeanne Piascik, Tina H. Buck, Sara Duff, Sai Deng

Faculty Scholarship and Creative Works

The University of Central Florida (UCF) Libraries’ Faculty Research Showcase has been a tradition of the library to highlight the publications, research projects, and scholarly accomplishments of library faculty members. The 2024 Showcase features seven presentations: "Alas, Babylon Afterword, Centipede Press (1959/2024)", "Throwback to Throwback Thinking: Integrating Archives into Student Engagement Activities", "Recent Research Activity: A Tale of Two Studies", "I Think I Can… I Think I Can…: Lessons in Persistence and Relationships from The Little Engine that Could", "A Hybrid Approach to Library Deaccessioning: A Case Study from the University of Central Florida", "KBART Automation vs Manual …


Norich, Anita, Sophia Maier Garcia Jul 2024

Norich, Anita, Sophia Maier Garcia

Bronx Jewish History Project

Summarizer: Sophia Maier

Anita Norich was born to two Holocaust survivor parents in a Displaced Persons camp called Föhrenwald in Germany. Despite difficulties acquiring visas because of her father’s left-wing political views, the family moved to the United States in March of 1957, settling on Hunts Point Avenue in the South Bronx. In Hunts Point, Norich attended PS 48, played outside and in a nearby park, and began her love for reading at the library. Starting kindergarten, she didn’t speak Englsih, and Norich describes the total immersion environment she was placed into. She felt it was cruel the teacher would …


Msl2 Variants Lead To A Neurodevelopmental Syndrome With Lack Of Coordination, Epilepsy, Specific Dysmorphisms, And A Distinct Episignature, Anoja Namasivayam, Jack Reilly, Michael A Levy, Raissa Relator, Jennifer Kerkhof, Haley Mcconkey, Maria Shvedunova, Andrea K Petersen, Kari Magnussen, Christiane Zweier, Georgia Vasileiou, André Reis, Juliann M Savatt, Meghan R Mulligan, Louise S Bicknell, Gemma Poke, Aya Abu-El-Haija, Jessica Duis, Vickie Hannig, Siddharth Srivastava, Elizabeth Barkoudah, Natalie S Hauser, Myrthe Van Den Born, Uri Hamiel, Noa Henig, Hagit Baris Feldman, Shane Mckee, Ingrid P C Krapels, Yunping Lei, Albena Todorova, Ralitsa Yordanova, Slavena Atemin, Mihael Rogac, Vivienne Mcconnell, Anna Chassevent, Kristin W Barañano, Vandana Shashi, Jennifer A Sullivan, Angela Peron, Maria Iascone, Maria P Canevini, Jennifer Friedman, Iris A Reyes, Janell Kierstein, Joseph J Shen, Faria N Ahmed, Xiao Mao, Berta Almoguera, Fiona Blanco-Kelly, Konrad Platzer, Ariana-Berenike Treu, Juliette Quilichini, Alexia Bourgois, Nicolas Chatron, Louis Januel, Christelle Rougeot, Deanna Alexis Carere, Kristin G Monaghan, Justine Rousseau, Kenneth A Myers, Bekim Sadikovic, Asifa Akhtar, Philippe M Campeau Jul 2024

Msl2 Variants Lead To A Neurodevelopmental Syndrome With Lack Of Coordination, Epilepsy, Specific Dysmorphisms, And A Distinct Episignature, Anoja Namasivayam, Jack Reilly, Michael A Levy, Raissa Relator, Jennifer Kerkhof, Haley Mcconkey, Maria Shvedunova, Andrea K Petersen, Kari Magnussen, Christiane Zweier, Georgia Vasileiou, André Reis, Juliann M Savatt, Meghan R Mulligan, Louise S Bicknell, Gemma Poke, Aya Abu-El-Haija, Jessica Duis, Vickie Hannig, Siddharth Srivastava, Elizabeth Barkoudah, Natalie S Hauser, Myrthe Van Den Born, Uri Hamiel, Noa Henig, Hagit Baris Feldman, Shane Mckee, Ingrid P C Krapels, Yunping Lei, Albena Todorova, Ralitsa Yordanova, Slavena Atemin, Mihael Rogac, Vivienne Mcconnell, Anna Chassevent, Kristin W Barañano, Vandana Shashi, Jennifer A Sullivan, Angela Peron, Maria Iascone, Maria P Canevini, Jennifer Friedman, Iris A Reyes, Janell Kierstein, Joseph J Shen, Faria N Ahmed, Xiao Mao, Berta Almoguera, Fiona Blanco-Kelly, Konrad Platzer, Ariana-Berenike Treu, Juliette Quilichini, Alexia Bourgois, Nicolas Chatron, Louis Januel, Christelle Rougeot, Deanna Alexis Carere, Kristin G Monaghan, Justine Rousseau, Kenneth A Myers, Bekim Sadikovic, Asifa Akhtar, Philippe M Campeau

Faculty, Staff and Students Publications

Epigenetic dysregulation has emerged as an important etiological mechanism of neurodevelopmental disorders (NDDs). Pathogenic variation in epigenetic regulators can impair deposition of histone post-translational modifications leading to aberrant spatiotemporal gene expression during neurodevelopment. The male-specific lethal (MSL) complex is a prominent multi-subunit epigenetic regulator of gene expression and is responsible for histone 4 lysine 16 acetylation (H4K16ac). Using exome sequencing, here we identify a cohort of 25 individuals with heterozygous de novo variants in MSL complex member MSL2. MSL2 variants were associated with NDD phenotypes including global developmental delay, intellectual disability, hypotonia, and motor issues such as coordination problems, feeding …


Correction: Type Of Cycle, Temperament And Childhood Trauma Are Associated With Lithium Response In Patients With Bipolar Disorders, Silvia Montanari, Evelina Bernardi, Giuseppe Carrà, Andrea Fiorillo, Gabriele Sani Jul 2024

Correction: Type Of Cycle, Temperament And Childhood Trauma Are Associated With Lithium Response In Patients With Bipolar Disorders, Silvia Montanari, Evelina Bernardi, Giuseppe Carrà, Andrea Fiorillo, Gabriele Sani

Faculty, Staff and Students Publications

This corrects the article "Type of cycle, temperament and childhood trauma are associated with lithium response in patients with bipolar disorders", 10.


Genome-Wide Analyses Reveal A Potential Role For The Mapt, Mobp, And Apoe Loci In Sporadic Frontotemporal Dementia, Claudia Manzoni, Carlos Cruchaga, Et Al. Jul 2024

Genome-Wide Analyses Reveal A Potential Role For The Mapt, Mobp, And Apoe Loci In Sporadic Frontotemporal Dementia, Claudia Manzoni, Carlos Cruchaga, Et Al.

2020-Current year OA Pubs

Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the field mainly focus on familial forms of disease (fFTDs), while studies of the genetic etiology of sporadic FTD (sFTD) have been less common. In the current work, we analyzed 4,685 sFTD cases and 15,308 controls looking for common genetic determinants for sFTD. We found a cluster of variants at the MAPT (rs199443; p = 2.5 × 10


Board Gender Diversity And Its Impact On Financial Performance And Risk-Taking: A Study Of Listed North American Companies, Ambrose Houphouet Jul 2024

Board Gender Diversity And Its Impact On Financial Performance And Risk-Taking: A Study Of Listed North American Companies, Ambrose Houphouet

Doctoral Dissertations (DBA)

In today's globalized world, gender diversity is increasingly recognized as vital for companies, yet women remain underrepresented in leadership positions. The lack of representation of women in leadership roles and their possible impact on business performance have led to a greater awareness of gender diversity on corporate boards in recent years. However, men dominate in some fields and the representation of women in decision-making levels is very low and it is unclear whether gender diversity brings any benefits to the company in terms of financial performance and risktaking. Therefore, the study examines the impact of gender diversity on financial performance …