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Interviewing The Interviewers: How Qualitative Professors Assess Interviews In Their Classes, Meredith C. Massey, Leia K. Cain

The Qualitative Report

When reviewing the literature relating to what instructors of qualitative research courses are teaching in their courses, we found a gap regarding qualitative faculty's motivations behind what they teach and whether they use teaching tools such as rubrics in their assessment practices. We utilized general qualitative methods to explore and describe how instructors of qualitative methodology courses conceptualize and design interview-based assessments. By conducting structured interviews with five faculty members, we embraced interpretivist descriptive traditions and sought to obtain thick, rich descriptions of each participant’s perspectives and experiences. After coding interview transcripts, we created themes to represent participant beliefs that …

Interannual Homing To Reproductive Sites And Transboundary Migration In Black Seabream Spondyliosoma Cantharus, With Implications For Management, Peter Davies, Thomas Stamp, Alice Hall, Allison Atterborne, Jen Lewis, George P Balchin, Alice Tebb, Sarah Ward, Francis Binney, Samantha Blampied, Alexander Plaster, Charlie Hubbard, Nick Rogers, Matthew Wiseman, Ronan Conlon, Shion E A Reynell, Emma V Sheehan

School of Biological and Marine Sciences

Fish spawning aggregations are vulnerable to overexploitation, which can have severe ecological, social, and economic consequences. Knowledge on the spatial ecology of aggregating species is often lacking, but is crucial for their effective conservation. This study explores the spawning site residency, interannual fidelity, and migration of black seabream Spondyliosoma cantharus using acoustic (n = 55) and conventional (n = 2397) tagging within and outside Marine Conservation Zones in the southern UK. Detections and recaptures of tagged fish indicated that black seabream display significant interannual fidelity to nesting areas, but that residency of individuals at nesting areas was short relative to …

High Impact Malware Targeting Maritime Infrastructure, Kevin Jones, Kimberly Tam

School of Engineering, Computing and Mathematics

Malware, of varying degrees of sophistication, is a growingproblem for any and all computing devices. With computing devices becoming more integrated into daily life across all sectors, malware has amore diverse cyberspace to affect. There is existent research examiningthe problem of malware from various perspectives: Personal Computers, smartphones, Internet of Things devices, etc. The majority of thisresearch has, in the past, focused on Information Technology (IT) devices and IT issues. More recently, there is an emerging body of workwith a focus on Operational Technology (OT), in various domains, suchas power grids, communication infrastructure, and factories. Unlike IT,OT directly monitors and/or …

September 4, 2024, Faculty, Illinois Wesleyan University

2024-2025

No abstract provided.

Caring For Adolescent Learners In The Virtual Classroom: Lessons From The Covid-19 Pandemic, Stephanie Welch, Jeasik Cho

The Qualitative Report

In the recent past, fully online instruction has been most prominent at the higher education level, though online K-12 schools have lately gained some traction. However, the COVID-19 pandemic precipitated new potential for rapid expansion of online K-12 education. As these settings continue to develop, the unique social emotional needs of adolescent learners must be considered, and the need for a robustly developed online pedagogy of care is pressing. An unexpected and untapped resource for developing a framework for an online pedagogy of care can be found in examining the practices of traditionally face-to-face teachers who were unexpectedly thrust into …

Tranq Dope: Characterization Of An Ed Cohort Treated With A Novel Opioid Withdrawal Protocol In The Era Of Fentanyl/Xylazine, Kory London, Yutong Li, Jennifer Kahoud, Davis Cho, Jamus Mulholland, Sebastian Roque, Logan Stugart, Jeffrey Gillingham, Elias Borne, Benjamin Slovis

Department of Emergency Medicine Faculty Papers

BACKGROUND: Treating opioid use disorder has reached a new level of challenge. Synthetic opioids and xylazine have joined the non-medical opioid supply, multiplying the complexities of caring for individuals in emergency departments (ED). This combination, known as 'tranq dope,' is poorly described in literature. Inadequate withdrawal treatment results in a disproportionately high rate of patient-directed discharges (also known as against medical advice dispositions, or AMA). This study aimed to describe a cohort of individuals who received a novel order set for suspected fentanyl and xylazine withdrawal in the ED.

METHODS: This is a descriptive study evaluating a cohort of ED …

Chylopericardium And Superior Vena Cava Syndrome Caused By Central Venous Occlusion From Indwelling Hemodialysis Catheters, Daniel Underberg, Nicholas Demario, Sebastian Rodriguez, Khulkar Mirzozoda, Mark Decaro, Gregary Marhefka

Division of Cardiology Faculty Papers

Chylopericardium is a rare condition. Causes include superior vena cava syndrome resulting from indwelling catheters. We present a case of this condition in a 42-year-old man with end-stage renal disease treated with hemodialysis through a right subclavian vein catheter. He underwent successful endovascular stenting with resolution of his symptoms and chylopericardium.

Staff Education Program To Enhance Patient Handover Communication, Olufemi Olawale

Walden Dissertations and Doctoral Studies

Patient handover communication is the process that occurs when nurses transfer responsibility for patient care and give status reports to nurses who are assuming care of the patient. The practice problem at the project site was the gap in quality, accuracy, and completeness of information that was shared during the handover process. The purpose of this project was to develop, implement, and evaluate a staff education program on effective communication handover between nurses and care providers. The practice-focused question for this project was: Will a staff education project increase nurses’ and clinicians’ knowledge and competency with using the situation, background, …

Perspectives In Embodiment Theory, Sana Saboowala, Maria Cox

Human Biology Open Access Pre-Prints

Researchers apply the concept of embodiment across many disciplines, resulting in a set of expansive definitions that only sometimes overlap. This special issue celebrates the plurality and wide applicability of this useful framework by bringing together multiple perspectives on embodiment within the field of human biology.

Different Sensory Information Is Used For State Estimation When Stationary Or Moving., Aaron Wong, Alyssa Eyssalenne, Luke Carter, Amanda S Therrien

Moss-Magee Rehabilitation Papers

The accurate estimation of limb state is necessary for movement planning and execution. While state estimation requires both feedforward and feedback information, we focus here on the latter. Prior literature has shown that integrating visual and proprioceptive feedback improves estimates of static limb position. However, differences in visual and proprioceptive feedback delays suggest that multisensory integration could be disadvantageous when the limb is moving. We formalized this hypothesis by modeling feedback-based state estimation using the long-standing maximum likelihood estimation model of multisensory integration, which we updated to account for sensory delays. Our model predicted that the benefit of multisensory integration …

Shabsigh, Dr.Ridwan, Mark Naison

Oral Histories

Abstract

INTERVIEWER: Grace Schmidt, Allison Leche

INTERVIEWEE: Ridwan Shabsigh (Dr. Shabsigh)

SUMMARY BY: Christine Rong

Originally from Syria, Dr. Ridwan Shabsigh, Chairman of Surgery at St. Barnabas Hospital, discussed his role, hardships, and experience working during the extreme surges of the COVID-19 pandemic. When the pandemic hit in early 2020, he led a hospital serving one of the most socioeconomically disadvantaged communities in New York City. The hospital, known for its critical care services, had to adapt to the overwhelming patient surge rapidly. The book Dr. Shabsigh co-authored documents this adaptation process, offering a detailed account of the hospital’s response. …

Information Resources Indices And Chemistry Collections Used In Nigerian University Libraries, Luqman Ayanlola Atanda, Grace Effiong Etukudo, Victoria Adeola Olukayode

Library Philosophy and Practice (e-journal)

The aim of this study was to ascertain how the use of chemistry collections in university libraries in Calabar, Cross River State, and Uyo, Akwa Ibom State, related to information resources indices. To direct the investigation, five distinct goals, five research questions were developed. In this study, the survey research design was used. In the investigation, the cluster sampling technique was applied.The population was made up of 297 individuals from both study areas, with 152 registered users of the University of Uyo's chemical library and 145 registered users of the University of Calabar's chemistry library. Data for the study were …

Fs Transcript 2024-09-04, Northern Illinois University

Faculty Senate Archives

No abstract provided.

Fs Agenda 2024-09-04, Northern Illinois University

Faculty Senate Archives

No abstract provided.

September 4, 2024 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

G Protein Selectivity Profile Of Gpr56/Adgrg1 And Its Effect On Downstream Effectors, Raida Jallouli, Ana L Moreno-Salinas, Andréanne Laniel, Brian Holleran, Charlotte Avet, Trang Hoang, Kendra S Carmon, Michel Bouvier, Richard Leduc

Faculty, Staff and Student Publications

GPR56, an adhesion G-protein coupled receptor (aGPCRs) with constitutive and ligand-promoted activity, is involved in many physiological and pathological processes. Whether the receptor's constitutive or ligand-promoted activation occur through the same molecular mechanism, and whether different activation modes lead to functional selectivity between G proteins is unknown. Here we show that GPR56 constitutively activates both G12 and G13. Unlike constitutive activation and activation with 3-α-acetoxydihydrodeoxygedunin (3αDOG), stimulation with an antibody, 10C7, directed against GPR56's extracellular domain (ECD) led to an activation that favors G13 over G12. An autoproteolytically deficient mutant, GPR56-T383A, was also activated by 10C7 indicating that the tethered …

Screening Of Anti-Prion Compounds Using The Protein Misfolding Cyclic Amplification Technology, Sandra Pritzkow, Isaac Schauer, Ananya Tupaki-Sreepurna, Rodrigo Morales, Claudio Soto

Faculty, Staff and Student Publications

Prion diseases are 100% fatal infectious neurodegenerative diseases affecting the brains of humans and other mammals. The disease is caused by the formation and replication of prions, composed exclusively of the misfolded prion protein (PrPSc). We invented and developed the protein misfolding cyclic amplification (PMCA) technology for in vitro prion replication, which allow us to replicate the infectious agent and it is commonly used for ultra-sensitive prion detection in biological fluids, tissues and environmental samples. In this article, we studied whether PMCA can be used to screen for chemical compounds that block prion replication. A small set of compounds previously …

Single-Cell And Spatial Proteo-Transcriptomic Profiling Reveals Immune Infiltration Heterogeneity Associated With Neuroendocrine Features In Small Cell Lung Cancer, Ying Jin, Yuefeng Wu, Alexandre Reuben, Liang Zhu, Carl M Gay, Xintong Zhou, Qi Zheng, Junyu Ren, Zhaoyuan Fang, Teng Peng, Nan Wang, Liang Ma, Yun Fan, Hai Song, Jianjun Zhang, Ming Chen

Faculty, Staff and Student Publications

Small cell lung cancer (SCLC) is an aggressive pulmonary neuroendocrine malignancy featured by cold tumor immune microenvironment (TIME), limited benefit from immunotherapy, and poor survival. The spatial heterogeneity of TIME significantly associated with anti-tumor immunity has not been systemically studied in SCLC. We performed ultra-high-plex Digital Spatial Profiling on 132 tissue microarray cores from 44 treatment-naive limited-stage SCLC tumors. Incorporating single-cell RNA-sequencing data from a local cohort and published SCLC data, we established a spatial proteo-transcriptomic landscape covering over 18,000 genes and 60 key immuno-oncology proteins that participate in signaling pathways affecting tumorigenesis, immune regulation, and cancer metabolism across 3 …

Crizotinib Enhances Parp Inhibitor Efficacy In Ovarian Cancer Cells And Xenograft Models By Inducing Autophagy, Janice M Santiago-O'Farrill, Alicia Blessing Bollu, Hailing Yang, Vivian Orellana, Marc Pina, Jinsong Liu, Zhen Lu

Faculty, Staff and Student Publications

Poly (ADP-ribose) polymerase inhibitors (PARPi) can encounter resistance through various mechanisms, limiting their effectiveness. Our recent research showed that PARPi alone can induce drug resistance by promoting autophagy. Moreover, our studies have revealed that anaplastic lymphoma kinase (ALK) plays a role in regulating the survival of ovarian cancer cells undergoing autophagy. Here, we explored whether the ALK-inhibitor crizotinib could enhance the efficacy of PARPi by targeting drug-induced autophagic ovarian cancer cell and xenograft models. Our investigation demonstrates that crizotinib enhances the anti-tumor activity of PARPi across multiple ovarian cancer cells. Combination therapy with crizotinib and olaparib reduced cell viability and …

Preexisting Skin-Resident Cd8 And Γδ T-Cell Circuits Mediate Immune Response In Merkel Cell Carcinoma And Predict Immunotherapy Efficacy, Zachary Z Reinstein, Yue Zhang, Oscar E Ospina, Matt D Nichols, Victoria A Chu, Alvaro De Mingo Pulido, Karol Prieto, Jonathan V Nguyen, Rui Yin, Carlos Moran Segura, Ahmed Usman, Brittney Sell, Spencer Ng, Janis V De La Iglesia, Sunandana Chandra, Jeffrey A Sosman, Raymond J Cho, Jeffrey B Cheng, Ellie Ivanova, Sergei B Koralov, Robbert J C Slebos, Christine H Chung, Nikhil I Khushalani, Jane L Messina, Amod A Sarnaik, Jonathan S Zager, Vernon K Sondak, Charles Vaske, Sungjune Kim, Andrew S Brohl, Xinlei Mi, Brian G Pierce, Xuefeng Wang, Brooke L Fridley, Kenneth Y Tsai, Jaehyuk Choi

Staff and Researcher Publications

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer with a ~50% response rate to immune checkpoint blockade (ICB) therapy. To identify predictive biomarkers, we integrated bulk and single-cell RNA-seq with spatial transcriptomics from a cohort of 186 samples from 116 patients, including bulk RNA-seq from 14 matched pairs pre- and post-ICB. In non-responders, tumors show evidence of increased tumor proliferation, neuronal stem cell markers, and IL-1. Responders have increased type I/II interferons and pre-existing tissue resident (Trm) CD8 or Vδ1 γδ T cells that functionally converge with overlapping antigen-specific transcriptional programs and clonal expansion of public TCRs. Spatial …

A Micro-Computed Tomographic Evaluation Of Maxillary First Molar Accessory Root Canal Morphology In A Black South African Subpopulation, Casper Jonker

Peninsula Dental School

PURPOSE: The aim of this study was to investigate the accessory root canal morphology of maxillary first molars in a Black South African subpopulation. METHODS: Micro-computed tomography was used to investigate 101 maxillary first molars (from 50 male and 51 female teeth, right 53 teeth, left 48 teeth). The prevalence of chamber canals, and the number, type and location (root third) of accessory canals were recorded. The relationships between arch side, sex and age were examined using chi-squared tests of association. Intra- and inter-observer reliability were assessed using Cohen's kappa test. RESULTS: Intra- and inter-rater agreement was 96.9% and 98.1%, …

Insights Into Foraging Behavior From Multi-Day Sound Recording Tags On Goose-Beaked Whales (Ziphius Cavirostris) In The Southern California Bight, Shannon N. Coates, David A. Sweeney, Erin A. Falcone, Stephanie L. Watwood, Brenda K. Rone, Stacy L. De Ruiter, Jay Barlow, Karin A. Dolan, Ronald P. Morrissey, Nancy A. Dimarzio, Susan M. Jarvis, Russel D. Andrews, Gregory S. Schor

University Faculty Publications and Creative Works

Goose-beaked whales (Ziphius cavirostris) are deep-diving cetaceans known for their elusive nature and specialized foraging behavior. In 2019 and 2020, six telemetry tags were deployed on these whales in Southern California, resulting in 395 h of acoustic and diving data. Foraging dives were manually identified by the presence of echolocation pulses and buzzes, and generalized additive models assessed factors influencing foraging behavior. The median bathymetric depth at foraging sites was 1,419 m (IQR = 359), and the maximum dive depth was highly correlated with bathymetry depth. Individuals started echolocating on descent at a median depth of 410 m (IQR = …

China Maritime Report No. 41: One Force, Two Force, Red Force, Blue Force: Pla Navy Blue Force Development For Realistic Combat Training, J. Michael Dahm

CMSI China Maritime Reports

Since the mid-2010s, there has been a concerted effort to professionalize a PLAN “blue force” as an opposition force, or OPFOR, in maritime exercises and training. The People’s Liberation Army (PLA) routinely refers to its blue forces as metaphorical “whetstones” used to sharpen the PLA for a future fight against enemies of the People’s Republic of China (PRC). Efforts to develop a PLAN blue force appear to have accelerated over the past several years in response to Chairman Xi Jinping’s decade-long demand for more realistic combat training.

This report examines recent developments in the PLAN’s blue force. It comprises four …

Left Coronary Artery Compression And Stent Fracture Following Self-Expanding Transcatheter Pulmonary Valve Implantation, Jeannette Wong-Siegel, Adam Naylor, David Balzer

2020-Current year OA Pubs

Coronary compression and vascular perforation have not been reported for self-expanding transcatheter pulmonary valves. We describe a patient with tetralogy of Fallot after self-expanding valve implantation who developed left coronary artery compression from the valve. In addition, a wire frame fracture resulted in perforation of the aorta.

A Genetic Screen In Drosophila Uncovers A Role For Senseless-2 In Surface Glia In The Peripheral Nervous System To Regulate Cns Morphology, Haluk Lacin, Yuqing Zhu, Jose T Dipaola, Beth A Wilson, Yi Zhu, James B Skeath

2020-Current year OA Pubs

Despite increasing in mass approximately 100-fold during larval life, the Drosophila CNS maintains its characteristic form. Dynamic interactions between the overlying basement membrane and underlying surface glia are known to regulate CNS structure in Drosophila, but the genes and pathways that establish and maintain CNS morphology during development remain poorly characterized. To identify genes that regulate CNS shape in Drosophila, we conducted an EMS-based, forward genetic screen of the second chromosome, uncovered 50 mutations that disrupt CNS structure, and mapped these alleles to 17 genes. Analysis of whole genome sequencing data wedded to genetic studies uncovered the affected gene for …

A Red Teaming Framework For Securing Ai In Maritime Autonomous Systems, Mathew J. Walter, Aaron Barrett, Kimberly Tam

School of Engineering, Computing and Mathematics

Artificial intelligence (AI) is being ubiquitously adopted to automate processes in science and industry. However, due to its often intricate and opaque nature, AI has been shown to possess inherent vulnerabilities which can be maliciously exploited with adversarial AI, potentially putting AI users and developers at both cyber and physical risk. In addition, there is insufficient comprehension of the real-world effects of adversarial AI and an inadequacy of AI security examinations; therefore, the growing threat landscape is unknown for many AI solutions. To mitigate this issue, we propose one of the first red team frameworks for evaluating the AI security …

Myc Induces Oncogenic Stress Through Rna Decay And Ribonucleotide Catabolism In Breast Cancer, Dianne Keough, Nagireddy Putluri, Panagiotis Katsonis, Amanda M Koire, Hyemin Lee, Elizabeth A Bowling, Siddhartha Tyagi, Mayra Orellana, Rocio Dominguez-Vidaña, Heyuan Li, Kenneth Eagle, Charles Danan, Hsiang-Ching Chung, Andrew D Yang, William Wu, Sarah J Kurley, Brian M Ho, Joseph R Zoeller, Calla M Olson, Kristen L Meerbrey, Olivier Lichtarge, Arun Sreekumar, Clifford C Dacso, Luke W Guddat, Dominik Rejman, Dana Hocková, Zlatko Janeba, Lukas M Simon, Charles Y Lin, Monica C Pillon, Thomas F Westbrook

Faculty, Staff and Students Publications

Upregulation of MYC is a hallmark of cancer, wherein MYC drives oncogenic gene expression and elevates total RNA synthesis across cancer cell transcriptomes. Although this transcriptional anabolism fuels cancer growth and survival, the consequences and metabolic stresses induced by excess cellular RNA are poorly understood. Herein, we discover that RNA degradation and downstream ribonucleotide catabolism is a novel mechanism of MYC-induced cancer cell death. Combining genetics and metabolomics, we find that MYC increases RNA decay through the cytoplasmic exosome, resulting in the accumulation of cytotoxic RNA catabolites and reactive oxygen species. Notably, tumor-derived exosome mutations abrogate MYC-induced cell death, suggesting …

Prospects And Challenges Of Tissue-Derived Extracellular Vesicles

Faculty, Staff and Students Publications

Extracellular vesicles (EVs) are considered a vital component of cell-to-cell communication and represent a new frontier in diagnostics and a means to identify pathways for therapeutic intervention. Recently, studies have revealed the importance of tissue-derived EVs (Ti-EVs), which are EVs present in the interstitial spaces between cells, as they better represent the underlying physiology of complex, multicellular tissue microenvironments in biology and disease. EVs are native, lipid bilayer membraned nano-sized particles produced by all cells that are packaged with varied functional biomolecules including proteins, lipids, and nucleic acids. They are implicated in short- and long-range cellular communication and may elicit …

The Prognostic Effect Of Infiltrating Immune Cells Is Shaped By Proximal M2 Macrophages In Lung Adenocarcinoma, Xiang Wang, Muhammad Aminu, Yong Li, Jia Wu, Jianjun Zhang, Christopher I Amos, Chao Cheng

Faculty, Staff and Students Publications

The spatial arrangement of immune cells within the tumor microenvironment (TME) and their interactions play critical roles in the initiation and development of cancer. Several advanced technologies such as imaging mass cytometry (IMC) providing the immunological landscape of the TME with single-cell resolution. In this study, we develop a new method to quantify the spatial proximity between different cell types based on single-cell spatial data. Using this method on IMC data from 416 lung adenocarcinoma patients, we show that the proximity between different cell types is more correlated with patient prognosis compared to the traditional features such immune cell density …