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Articles 33361 - 33390 of 5205763
Full-Text Articles in Entire DC Network
Humanitarianism Through Alan Kurdi Photograph: A Discourse Of Governing Suffering, Nada Mahmoud
Humanitarianism Through Alan Kurdi Photograph: A Discourse Of Governing Suffering, Nada Mahmoud
Theses and Dissertations
Humanitarianism has become one of the powerful languages of modern times, in which compassion, ethics, and moral obligations are mediated to alleviate suffering. This thesis investigates humanitarianism not exclusively on the basis of its moral sentiments but on its functioning as a system of power that governs people’s conduct. It examines how different technologies of power feed into the operationalization of humanitarianism to transform it into a system for governing suffering. By decoding the elements of its power, the thesis aims to understand humanitarian reason through the humanitarian loop, from generating knowledge, categorization and representation, to the legal and normative …
Energy Efficient Load Balancing In Multi-Band Cellular Networks Via Reinforcement Learning, Ahmed Shoukry El Soukkary
Energy Efficient Load Balancing In Multi-Band Cellular Networks Via Reinforcement Learning, Ahmed Shoukry El Soukkary
Theses and Dissertations
This thesis investigates energy-efficient load balancing in homogeneous multi-band cellular networks through the joint design of user association (UA) and transmit power allocation (PA). The original mixed-integer nonlinear formulation is decomposed into two coupled yet tractable subproblems: a UA stage and a PA stage for high-frequency bands. For UA, a SINR-ratio-based heuristic is proposed to prioritize users that are most sensitive to suboptimal band assignments, and it is benchmarked against a Max- SINR baseline. For PA, the high-band power control problem is addressed using reinforcement learning, where a Proximal Policy Optimization (PPO) agent learns power levels and band-activation decisions under …
Scruples Before Religion: Muslim Waraʿ Of The Formative Period, Omar Laaroussi
Scruples Before Religion: Muslim Waraʿ Of The Formative Period, Omar Laaroussi
Theses and Dissertations
This thesis studies the conceptual history of waraʿ and its role as a normative paradigm existing in the formative centuries of the Islamic world. To do so, I consider the Hellenic concepts that ground Near Eastern understandings of virtue and piety before the rise of Islam. This, I then use to contextualise a focused discussion on the textual history of waraʿ before moving on to discuss its properties in a ascetic social-world through the analysis of those very texts. I attempt to place those properties in conversation with modern philosophers’ work on disciplinary regimes and their impacts upon the self. …
Parental Gender Bias In Youth Employment Standards: Evidence From Upper Egypt, Mahmoud Saeed
Parental Gender Bias In Youth Employment Standards: Evidence From Upper Egypt, Mahmoud Saeed
Theses and Dissertations
Youth unemployment remains a critical challenge in Egypt, with female labor force participation among the lowest globally. While structural factors such as limited job creation and public sector contraction are well-documented, the role of family-level decision-making in constraining women's labor market entry has received limited quantitative attention. This thesis examines parental gender bias in employment standards in Upper Egypt, investigating whether and how parents impose systematically different job requirements for daughters compared to sons. Using primary survey data from 17,284 unemployed youth aged 18-35 across six governorates, paired with responses from their parents, this study analyzes parental preferences across six …
Mobilizing Social Capital In Social Entrepreneurship: Strategies, Networks, And Growth In The Egyptian Context, Doaa Alaa
Theses and Dissertations
This thesis examines how social entrepreneurs in Egypt strategically mobilise social capital to access resources, legitimacy, and opportunities within a fragmented and institutionally ambiguous ecosystem. Drawing on qualitative case studies of eight legally registered, mission-driven for-profit enterprises, the study analyses how founders build and leverage offline and online networks through practices such as emotional bonding, community formation, knowledge sharing, symbolic positioning, ecosystem engagement, and digital presence. Through thematic analysis of semi-structured interviews and secondary data, the research identifies a set of relational strategies that function as core mechanisms for entrepreneurial growth in contexts where formal support structures and legal definitions …
Tuning Ion Mobility And Molecular Confinement In High-Performance Polymer Electrolytes For Energy Storage, Ezzeldien Yousef Muhammed Yousef
Tuning Ion Mobility And Molecular Confinement In High-Performance Polymer Electrolytes For Energy Storage, Ezzeldien Yousef Muhammed Yousef
Theses and Dissertations
This research addresses the critical energy density limitations of aqueous supercapacitors, which are traditionally constrained by the narrow electrochemical stability window (ESW) of water 1.23 V. By employing two distinct molecular engineering strategies, this study developed high-performance electrolyte systems that significantly extend voltage stability and thermal resilience.
The first system, CsBr@PAM/HA, utilizes a polyacrylamide and hyaluronic acid hydrogel matrix. This system exploits the chaotropic nature of Cs+ ions to disrupt the aqueous hydrogen-bonding network, enhancing ionic conductivity to 104 mS cm-1. Through systematic salt screening, CsBr was identified as the optimal electrolyte, enabling a stable 2.0 V …
Social Identity And Language Learning/Teaching Trajectories: Egyptian English Teachers’ Reflections On Being Taught By Native English- Speaking Instructors, Asmaa Mohamed Badawy
Social Identity And Language Learning/Teaching Trajectories: Egyptian English Teachers’ Reflections On Being Taught By Native English- Speaking Instructors, Asmaa Mohamed Badawy
Theses and Dissertations
This study explores how teacher social identity is shaped by Egyptian English teachers’ past learning experiences, particularly in relation to native and non-native English-speaking teachers. It seeks to understand how these experiences influence teachers’ perceptions of themselves within English-speaking contexts and how they make sense of dominant language ideologies surrounding nativeness. The study is guided by the following research questions: how participants perceive their sense of social belonging within English-speaking contexts; how ‘native’ and ‘non-native’ English teachers understand and interpret nativeness; and how past educational and social experiences shape teachers’ sense of ownership and legitimacy. Situated within the framework of …
How Disability Inclusion Shapes Student Experiences In Egyptian Public Universities, Ramez Maher
How Disability Inclusion Shapes Student Experiences In Egyptian Public Universities, Ramez Maher
Theses and Dissertations
The inclusion of students with disabilities in higher education is a critical aspect of equity, social justice, and human rights, particularly in Egypt, where systemic barriers continue to hinder access to education for this demographic. Despite the enrollment of approximately 19.4 million students in 2018, only 38,135 students with disabilities were admitted, highlighting the significant challenges they face in accessing higher education. Through a qualitative approach employing reflexive thematic analysis, this study explores the interplay of institutional policies, cultural attitudes, and accessibility challenges that affect the educational experiences of students with disabilities in Egyptian public universities. The analysis of 21 …
From Aspiration To Obligation: A Contractual Sustainability Framework For The Egyptian Construction Industry, Salma Ali
Theses and Dissertations
The construction industry is responsible for approximately 40% of global energy consumption and 35% of total waste generation, making it one of the most significant contributors to the global sustainability challenge. In Egypt, that challenge takes a specific contractual form. Egypt’s construction sector contributes approximately 23% of national energy consumption, yet the survey findings reveal that 63.5% of construction professionals report that sustainability clauses rarely or never appear in contracts, and only 11.5% confirm the presence of enforceable provisions with measurable targets. This gap is structural rather than attitudinal. Competitive procurement penalises voluntary sustainability investment, and without contractual obligation, awareness …
The Informal Impact Of The Headscarf Ban On Veiled Students’ Everyday University Experiences In Paris, Farah K. Lotfy
The Informal Impact Of The Headscarf Ban On Veiled Students’ Everyday University Experiences In Paris, Farah K. Lotfy
Theses and Dissertations
This study examines the informal impact of the 2004 headscarf ban on the everyday university experiences of veiled students in Paris. Although the ban applies formally to public schools rather than universities, the wider social climate surrounding laïcité and the veil continues to influence how veiled students experience visibility, belonging, and participation in higher education.
Using a qualitative approach based primarily on semi-structured interviews, supported by informal observations conducted within university spaces in Paris, the study explores how exclusion is experienced through stereotypes, scrutiny, social discomfort, self-monitoring, and anticipation of discrimination rather than through formal university policy. The research focuses …
Engineering Nanoelectrocatalytic Systems For Co2 And Nitrate Conversion Into Value-Added Chemicals, Abdelrahman Mohamed Abdelmohsen
Engineering Nanoelectrocatalytic Systems For Co2 And Nitrate Conversion Into Value-Added Chemicals, Abdelrahman Mohamed Abdelmohsen
Theses and Dissertations
The thesis addresses two major related environmental crises: nitrate pollution of water systems and the ever-increasing levels of atmospheric carbon dioxide. Both challenges are closely linked to anthropogenic disturbance of nitrogen and carbon cycles and require sustainable, energy efficient mitigation techniques. In this study, we investigate electrochemical conversion routes as a unified approach to convert these pollutants into value-added compounds: ammonia (NH3) via nitrate reduction (NO3-RR) and ethylene (C2H4) via carbon dioxide reduction (CO2RR). The first half of this work deals with the design and engineering of Cu-Zn alloy electrocatalysts for efficient NO3-RR. Tuning the alloy composition and surface nanostructure …
Flexible-Mode Multi-Skilled Resource-Constrained Project Scheduling Problem With Setup Times: Application In The Oil And Gas Industry, Safinaz M. El Dawody
Flexible-Mode Multi-Skilled Resource-Constrained Project Scheduling Problem With Setup Times: Application In The Oil And Gas Industry, Safinaz M. El Dawody
Theses and Dissertations
Turnaround maintenance (TAM) in the petroleum refining sector requires coordinating geographically dispersed project portfolios under stringent resource, schedule, and budget constraints. Conventional scheduling models treat tasks in isolation, failing to account for shared resources, crew fatigue, or inter-site transit. To bridge this gap, this study introduces and empirically validates a Flexible-Mode Multi-Skilled Resource-Constrained Project Scheduling Problem with Setup Times (FM-MS-RCPSP-ST). Applied to a real-world portfolio of 76 TAM projects across five governorates in Egypt, the framework is operationalized through an 11-stage pipeline integrating NSGA-II multi-objective optimization, GIS-based routing, and 500-trial Monte Carlo disruption simulations.
Results demonstrate that incorporating mandatory crew-rest …
The Effect Of Mwcnt-Oil Impregnation Of Sintered Components On Their Wear And Corrosion Resistance, Maha Khaled Abdelfadeel
The Effect Of Mwcnt-Oil Impregnation Of Sintered Components On Their Wear And Corrosion Resistance, Maha Khaled Abdelfadeel
Theses and Dissertations
Powder Metallurgy (PM) offers an advantageous route for manufacturing complex and near net-shape components. Their inherent interconnected porosity that promotes the action of self lubrication compromises their structural integrity by creating pathways for corrosion and excessive wear. This research investigates the efficacy of Multi-Walled Carbon Nanotubes (MWCNTs) as a nano additive within the impregnating base oil (SN-150 base oil). An experimental matrix was designed to evaluate the influence of MWCNTs with different concentrations of 0.05, 0.1, and 0.2 wt.% and ultrasonic dispersion with varying sonication times of 30 and 60 minutes on the tribological and electrochemical performance of sintered steel …
Who Moderates? A Polycentric Framework For Allocating Regulatory Responsibility In Online Content Moderation, Farh A. El Wishi
Who Moderates? A Polycentric Framework For Allocating Regulatory Responsibility In Online Content Moderation, Farh A. El Wishi
Theses and Dissertations
The question of who is responsible for content moderation on the internet remains one of the key topics relating to internet governance. Legislation has been adopted, platforms have utilized self-regulation methods, and users have flagged and reported content, all often happening simultaneously, yet rarely according to any coherent principle for deciding which actor should bear primary responsibility for which aspect of the problem. This research argues that the absence of a principled allocative framework is the central governance failure of the internet's regulatory history, and that addressing it requires a structured distribution of regulatory responsibility across the three actors who …
Michigan's Automotive Workforce Transition, Erik Vasilauskas, Michael Horrigan
Michigan's Automotive Workforce Transition, Erik Vasilauskas, Michael Horrigan
Upjohn Institute Technical Reports
This report examines how changes in automobile production, specifically the shift from internal-combustion-engine (ICE) vehicles toward hybrids and battery-electric vehicles (BEVs), are likely to affect employment in Michigan’s automotive manufacturing and distribution system over the next decade. The goal is to quantify how many jobs in Michigan depend on the automotive supply chain today, how that employment has evolved since the early 2000s, and how it may change through 2030 under alternative production-and-demand scenarios. The results are intended to inform the workforce planning and community transition strategies of the Michigan Department of Labor and Economic Opportunity’s Community and Worker Economic …
Gpr182 Is A Lipoprotein Receptor For Dietary Fat Absorption, Zhiwei Sun, Gwendalyn J. Randolph, Et Al.
Gpr182 Is A Lipoprotein Receptor For Dietary Fat Absorption, Zhiwei Sun, Gwendalyn J. Randolph, Et Al.
2020-Current year OA Pubs
The lymphatic system plays a central role in lipid absorption by transporting triglyceride-rich particles called chylomicrons (CMs) from the small intestine to the systemic circulation. However, the molecular mechanism by which CMs get into the intestinal lymphatics is unknown. Here, we demonstrated that GPR182, an atypical chemokine receptor in lymphatic endothelial cells, mediates dietary fat absorption. GPR182-KO mice exhibited a selective increase in circulating high-density lipoproteins and are resistant to diet-induced obesity. GPR182 ablation in mice led to poor lipid absorption and thereby a delay in growth during development. GPR182 broadly interacted with and transported lipoproteins. Transmission electron microscopy analysis …
The N-Terminus Of Apolipoprotein B Mediates The Interaction Of Atherogenic Lipoproteins With Endothelial Cells, Ainara G. Cabodevilla, Nicholas O. Davidson, Et Al.
The N-Terminus Of Apolipoprotein B Mediates The Interaction Of Atherogenic Lipoproteins With Endothelial Cells, Ainara G. Cabodevilla, Nicholas O. Davidson, Et Al.
2020-Current year OA Pubs
Apolipoprotein B-containing (APOB-containing) lipoproteins contribute to atherosclerosis by entering the arterial wall through the endothelial cell (EC) surface receptors scavenger receptor-BI (SR-BI) and activin receptor-like kinase 1 (ALK1). We used N-terminal fragments of APOB, molecular modeling, and site-directed mutagenesis to identify and block the binding of chylomicrons and LDL to these receptors in cells and mice. We discovered that different APOB regions interact with SR-BI and ALK1 expressed on ECs. APOB48 lipoproteins were only internalized by SR-BI. A fragment of APOB comprising 18% of the N-terminal sequence, APOB18, reduced the uptake and transport of both chylomicrons and LDL by ECs, …
The Kashmir Conflict After The Abrogation Of Articles 370 And 35a Of The Indian Constitution: Geopolitical Dynamics And Human Security Implications, Rizwan Ali
Dissertations and Theses
The abrogation of Article 370 of the Indian Constitution on August 5, 2019, revoked the special autonomous status of Jammu and Kashmir (J&K) under the Indian administration. It further bifurcated it into two Union Territories under central Indian control. The move came amid a severe security lockdown and communication blackout that lasted for months. It was followed by instrumental legal, social, and economic developments that directly affected the area’s disputed status and the human rights of its residents. This research examines the geopolitical and human security implications of the abrogation and subsequent developments through a qualitative, analytical design, integrating Edward …
Vitamin D Deficiency And Adverse Cardiovascular, Metabolic, And Mortality Outcomes In Adults With Obstructive Sleep Apnea: A Propensity-Matched Retrospective Cohort Study, Andrew Cecil, Ekow Essien, Abena Agyekum, Gloria Amoako
Vitamin D Deficiency And Adverse Cardiovascular, Metabolic, And Mortality Outcomes In Adults With Obstructive Sleep Apnea: A Propensity-Matched Retrospective Cohort Study, Andrew Cecil, Ekow Essien, Abena Agyekum, Gloria Amoako
Aurora GME
OBJECTIVE: Vitamin D deficiency is highly prevalent in obstructive sleep apnea (OSA) and implicated in metabolic dysregulation and cardiovascular disease. This study examined associations between vitamin D deficiency and adverse cardiovascular, metabolic, and mortality outcomes in adults with OSA.
METHODS: This retrospective cohort study utilized the TriNetX Global Collaborative Network spanning 155 healthcare organizations. Adults (≥18 years) with OSA (ICD-10: G47.33) were stratified by serum 25-hydroxyvitamin D3 into deficient (≤12 ng/mL, n=64,205) and sufficient (≥20 ng/mL, n=64,205) cohorts following 1:1 propensity matching. Primary outcomes included all-cause mortality, myocardial infarction, heart failure, pulmonary embolism, chronic kidney disease, hypertension, type 2 diabetes, …
Making A Makerspace: The Innervate Lab As A Reimagined Technology Education Space, Raaghav Pandya, Euisuk Sung, Caroline Darin
Making A Makerspace: The Innervate Lab As A Reimagined Technology Education Space, Raaghav Pandya, Euisuk Sung, Caroline Darin
Publications and Research
With the growing emphasis on creativity, collaboration, and reflective thinking in technology and design education, technology labs are expected to shift from technical priorities to open, collaborative spaces. Designed within an existing technology education facility, the paper explored what it means to “technology lab” that merges the technical with the reflective, the cultural with the material, and the innovative with the contemplative. This paper presents the intellectual and aesthetic journey of creating an innovative makerspace within a technology education context and explains how this work embodies a sustainable model for training future technology educators. Our approach was informed by the …
Provocation In Philosophical Practice, Kathryn Elizabeth Cook, Sara Dorrego Carreira, Anca-Cornelia Tiurean
Provocation In Philosophical Practice, Kathryn Elizabeth Cook, Sara Dorrego Carreira, Anca-Cornelia Tiurean
Faculty and Staff Publications & Presentations
Challenging conventional notions of comfort and safety in philosophical practice, this article argues for the primacy of reason in the work to provoke and exercise thinking. Exercising thinking involves problematization and conceptualization of cherished ideas and attitudes. Consequently, philosophical consultations can be uncomfortable; rather than seeking to alleviate this discomfort, this article examines it directly. Assumptions that discomfort is harmful, consultation is dangerous, philosophers are therapists, or success is mandated are actively problematized. The authors appreciate the growth promoting role of discomfort, see the beauty of exercising the thinking capacity, and respect the thinking competence of all people. The authors …
The Purple Owl, March 1922, The Times Print, Florence, Ala.
The Purple Owl, March 1922, The Times Print, Florence, Ala.
Documents
March 1922 publication of The Purple Owl at State Normal School.
The Purple Owl, November 1922, State Normal School
The Purple Owl, November 1922, State Normal School
Documents
November 1922 publication of The Purple Owl at State Normal School.
Monospecific Mass Occurrence Of The Dimerelloid Brachiopod Halorella Amphitoma In A Shallow Marine Environment Of The Late Triassic Dachstein Platform (Bakony Mountains, Hungary), Tamás Müller, Attila Vörös, János Haas, Tamás Budai, Clemens V. Ullmann, Gregory D. Price, József Pálfy
Monospecific Mass Occurrence Of The Dimerelloid Brachiopod Halorella Amphitoma In A Shallow Marine Environment Of The Late Triassic Dachstein Platform (Bakony Mountains, Hungary), Tamás Müller, Attila Vörös, János Haas, Tamás Budai, Clemens V. Ullmann, Gregory D. Price, József Pálfy
School of Geography, Earth and Environmental Sciences
Dimerelloid brachiopods with patchy but cosmopolitan geographical distribution, including the Late Triassic (Norian) Halorella amphitoma, offer a unique opportunity to identify and reconstruct specific palaeo-microenvironments in the geological past. The group and this species are commonly associated with hydrocarbon seepage in Palaeozoic and Mesozoic records. In addition, mass occurrences of H. amphitoma are also known from neptunian dykes and palaeokarst cavities on the vast Late Triassic Dachstein carbonate platform. It has been suggested that the shells were either washed into these structures or the animals were living directly there in a dark environment, but normal marine conditions were implied for …
Detection Of C60 Combination Bands In The Near-Ir Spectrum Of Tc 1, Morgan M. Giese, Vincent J. Esposito, Simon Van Schuylenbergh, Jan Cami, Els Peeters, Charmi Bhatt, Dries Van De Putte, A. G. G. M. Tielens, Michael J. Barlow, Jeronimo Bernard-Salas, Alessandra Candian, Bryan Changala, Nick L. J. Cox, Harriet L. Dinerstein, D. A. García-Hernández, Marco A. Gómez-Muñoz, Kay Justtanont, Kathleen E. Kraemer, Eric Lagadec, Arturo Manchado, Ana Monreal Ibero, Raghvendra Sahai, Ameek Sidhu, G. C. Sloan, N. C. Sterling, Jeremy R. Walsh, Roger Wesson, Joshua Cole Whitman, Albert Zijlstra
Detection Of C60 Combination Bands In The Near-Ir Spectrum Of Tc 1, Morgan M. Giese, Vincent J. Esposito, Simon Van Schuylenbergh, Jan Cami, Els Peeters, Charmi Bhatt, Dries Van De Putte, A. G. G. M. Tielens, Michael J. Barlow, Jeronimo Bernard-Salas, Alessandra Candian, Bryan Changala, Nick L. J. Cox, Harriet L. Dinerstein, D. A. García-Hernández, Marco A. Gómez-Muñoz, Kay Justtanont, Kathleen E. Kraemer, Eric Lagadec, Arturo Manchado, Ana Monreal Ibero, Raghvendra Sahai, Ameek Sidhu, G. C. Sloan, N. C. Sterling, Jeremy R. Walsh, Roger Wesson, Joshua Cole Whitman, Albert Zijlstra
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
We report the detection of a set of new near-infrared emission features between 3.5 and 5.2 μm in JWST/NIRSpec observations of Tc 1, the planetary nebula known for displaying the cleanest and most prominent mid-infrared cosmic fullerene spectrum. These broad features share the same spatial distribution as the well-known C60 and C70 mid-infrared emission bands, peaking in an asymmetric ring approximately 5″–6″ from the central star. Through comparison with new anharmonic quantum chemical calculations, we demonstrate that these features arise from C60 combination bands, marking their first detection in an astrophysical environment. The total energy radiated …
Macropinocytosis Inhibition Attenuates Profibrotic Responses In Lung Fibroblasts And Pulmonary Fibrosis Models, Ivan O Rosas, Aaron K Mcdowell-Sanchez, Santiago Sanchez, Juan D Cala-Garcia, Alan R Waich Cohen, Elisa Ruiz-Echartea, Scott A Ochsner, Daniel C Kraushaar, Lindsay J Celada, Dandan Sun, Francesca Polverino, Cristian Coarfa, Neil J Mckenna, Konstantin Tsoyi
Macropinocytosis Inhibition Attenuates Profibrotic Responses In Lung Fibroblasts And Pulmonary Fibrosis Models, Ivan O Rosas, Aaron K Mcdowell-Sanchez, Santiago Sanchez, Juan D Cala-Garcia, Alan R Waich Cohen, Elisa Ruiz-Echartea, Scott A Ochsner, Daniel C Kraushaar, Lindsay J Celada, Dandan Sun, Francesca Polverino, Cristian Coarfa, Neil J Mckenna, Konstantin Tsoyi
Faculty, Staff and Students Publications
Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disorder with limited treatment options. Macropinocytosis is one of the key cellular processes involved in nutrient consumption from the extracellular environment under stress conditions. Here, we studied the role of macropinocytosis in experimental pulmonary fibrosis models. We found that macropinocytosis is increased in human lung fibroblasts (HLFs) derived from patients with IPF. The inhibition of macropinocytosis with 5-(n-ethyl-n-isopropyl)-amiloride (EIPA) inhibited profibrotic responses in IPF-derived and TGF-β1-stimulated HLFs and reduced pulmonary fibrosis in bleomycin-injured (Bleo-injured) mice. EIPA exerted its antifibrotic effects by regulating amino acid uptake, mammalian target of rapamycin complex 1 …
Guideline On Stress Echocardiography - 2026, Ana Cristina Camarozano, Salvador Vicente Spina, José Roberto Matos Souza, Marcelo Dantas Tavares De Melo, Daniela Do Carmo Rassi Frota, Silvio Henrique Barberato, Fabio Villaça Guimarães Filho, Harry Acquatella, Vera Márcia Lopes Gimenes, Jorge Alfredo Lowenstein, Ricardo H Pignatelli, José Maria Del Castillo, Joselina Luiza Menezes Oliveira, José Sebastião De Abreu, José Luis De Castro E Silva Pretto, Issam Shehadeh, Alex Dos Santos Felix, Mercedes Maldonado Andrade, Antônio Carlos Sobral Sousa, Maria Estefânia Bosco Otto, Andrea De Andrade Vilela, Pedro Gutierrez Fajardo, Liz Andréa Villela Baroncini, Cristiano Vieira Machado, Fábio Cañellas Moreira, José María Hernández Hernández, Marco Stephan Lofrano Alves, Samira Saady Morhy, Márcio Silva Miguel Lima, Miguel Osman Dias Aguiar, Wilson Mathias Junior, Letícia Dos Santos De Oliveira Rocha, João César Nunes Sbano, Barbara Athayde Linhares Martins Vrandecic, Fabio Roston, Arnaldo Rabischoffsky, Juliana Paixão Etto Rolim, Raphael Aparecido Barreto Da Silva, Guilherme De Rossi, Kamila Fernanda Staszko, Jolie Britt, Marcelo Luiz Campos Vieira
Guideline On Stress Echocardiography - 2026, Ana Cristina Camarozano, Salvador Vicente Spina, José Roberto Matos Souza, Marcelo Dantas Tavares De Melo, Daniela Do Carmo Rassi Frota, Silvio Henrique Barberato, Fabio Villaça Guimarães Filho, Harry Acquatella, Vera Márcia Lopes Gimenes, Jorge Alfredo Lowenstein, Ricardo H Pignatelli, José Maria Del Castillo, Joselina Luiza Menezes Oliveira, José Sebastião De Abreu, José Luis De Castro E Silva Pretto, Issam Shehadeh, Alex Dos Santos Felix, Mercedes Maldonado Andrade, Antônio Carlos Sobral Sousa, Maria Estefânia Bosco Otto, Andrea De Andrade Vilela, Pedro Gutierrez Fajardo, Liz Andréa Villela Baroncini, Cristiano Vieira Machado, Fábio Cañellas Moreira, José María Hernández Hernández, Marco Stephan Lofrano Alves, Samira Saady Morhy, Márcio Silva Miguel Lima, Miguel Osman Dias Aguiar, Wilson Mathias Junior, Letícia Dos Santos De Oliveira Rocha, João César Nunes Sbano, Barbara Athayde Linhares Martins Vrandecic, Fabio Roston, Arnaldo Rabischoffsky, Juliana Paixão Etto Rolim, Raphael Aparecido Barreto Da Silva, Guilherme De Rossi, Kamila Fernanda Staszko, Jolie Britt, Marcelo Luiz Campos Vieira
Faculty, Staff and Students Publications
No abstract provided.
Autophagic Flux Blockade Under Hypocapnia Reveals Co2-Sensitive Regulation Of Autophagy-Lysosome Homeostasis, Naghmana Ashraf, Zhen Sun, Jeanine L Van Nostrand
Autophagic Flux Blockade Under Hypocapnia Reveals Co2-Sensitive Regulation Of Autophagy-Lysosome Homeostasis, Naghmana Ashraf, Zhen Sun, Jeanine L Van Nostrand
Faculty, Staff and Students Publications
Hypocapnia, a reduction in partial pressure of carbon dioxide (CO2), commonly occurs in clinical contexts such as mechanical ventilation, panic disorder, and brain injury, yet its impact on cellular homeostasis remains poorly understood. Given the central role of autophagy in stress adaptation, we investigated how low CO2 influences autophagic flux and lysosomal function. We found that hypocapnia induces autophagosome accumulation while impairing cargo degradation, indicating a blockade in autophagic flux. This response was accompanied by increased lysosome biogenesis but, paradoxically, reduced autophagosome-lysosome fusion and lysosomal proteolytic activity. Mechanistically, hypocapnia promoted TFE3 dephosphorylation and nuclear translocation, driving transcriptional activation of lysosomal …
Ultrasound-Enabled Refreshable Electrochemical Sensors For Cardiac Biomarker Monitoring, Mayank Garg, Heng Guo, Myeong Namkoong, Elizabeth Zhanov, Connor Malone, Md Saifur Rahman, Ayse Akcan-Arikan, Limei Tian
Ultrasound-Enabled Refreshable Electrochemical Sensors For Cardiac Biomarker Monitoring, Mayank Garg, Heng Guo, Myeong Namkoong, Elizabeth Zhanov, Connor Malone, Md Saifur Rahman, Ayse Akcan-Arikan, Limei Tian
Faculty, Staff and Students Publications
Cardiac troponin I (cTnI) is the gold-standard biomarker for acute myocardial infarction, yet current laboratory-based high-sensitivity assays require centralized infrastructure, trained personnel, and serial testing, limiting their suitability for real-time or continuous monitoring in resource-limited settings. Point-of-care electrochemical sensors have shown promise for rapid cTnI detection, but their reliance on antibodies as biorecognition elements and redox mediator solutions, and single-use operation restricts practical translation. Here, we report an ultrasound-enabled refreshable electrochemical biosensor for sensitive, stable, and repeatable cTnI monitoring. The device employs a cTnI-specific peptide as the biorecognition element, providing enhanced stability during storage, transport, and operation. Label-free electrochemical impedance …
Eddy Current Generated From Bicyle Brake Disc., John Riley Mr
Eddy Current Generated From Bicyle Brake Disc., John Riley Mr
Defensive Publications Series
A magnet & coil assembly situated close to (but not in direct physical contact) a bicycle brake disc which when rotating, generates an eddy current creating electricity for bike lights.