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Complicity, Eliana Luxemburg-Peck Sep 2024

Complicity, Eliana Luxemburg-Peck

Dissertations, Theses, and Capstone Projects

What does it mean to be complicit in diffuse collective wrongs like structural racism, gender-based oppression, or environmental damage, and what responsibilities are entailed by complicity? Moral philosophers have often understood complicity to consist in some degree of inherited culpability, arising from knowing or intentional contributions to the bad acts of a primary wrongdoer. But these theories fail to explain complicity in the foregoing contexts, and cannot justify needed efforts to hold individuals accountable for unwitting contributions to systemic wrongs and injustices. In response to this gap, my dissertation defends a novel reconceptualization of complicity as participation in collectively perpetrated …


Careful Compositions And Careless Constructions, Timothy Dalton Sep 2024

Careful Compositions And Careless Constructions, Timothy Dalton

Dissertations, Theses, and Capstone Projects

This dissertation uses digital methods to analyze a digitized archive of life writing by disabled Civil War veterans through lenses of care ethics and rhetorical genre theory. Autobiographical letters by more than 370 disabled men respond to a contest prompt open to Union veterans injured in their right arms who had to relearn penmanship. This dissertation introduces the hybrid genre of “specimens of left-hand penmanship” through several critical lenses. It critiques the rhetoric of vocational rehabilitation and examines this archive as a site for early examples of concepts from contemporary disability studies. Finally, it turns explicitly to care ethics, and …


Education Crowdfunding Success: Studies On Information Asymmetry And Information Overload In Online Platforms, Mingyan Xu Sep 2024

Education Crowdfunding Success: Studies On Information Asymmetry And Information Overload In Online Platforms, Mingyan Xu

Dissertations, Theses, and Capstone Projects

Online education crowdfunding attracts public school teachers with its enormous outsourcing opportunities, but its success is constantly challenged by information asymmetry and information overload. To assist the teachers in successfully collecting teaching funds in crowdfunding, three studies are conducted to address the two challenges.

Information asymmetry exists between the fundraising teachers and the potential donors and challenges the education crowdfunding success. Virtual communication setting of online context further exacerbates this issue. Following signaling theory, it is critical for the informed teachers to create and send quality signals to the less-informed donors to enhance communication and establish mutual understanding. To understand …


Autophagy And Meiotic Fidelity In C. Elegans, Kaitlin E. Kosinski Sep 2024

Autophagy And Meiotic Fidelity In C. Elegans, Kaitlin E. Kosinski

Dissertations, Theses, and Capstone Projects

Autophagy is an evolutionarily conserved multi-step recycling process in which cellular material is enclosed in the double membrane-bound autophagosome, which fuses with the lysosome to degrade its contents. Autophagy is essential for development and cellular adaptation to environmental or intracellular stress and is an important regulator of germline stem cell homeostasis in the model nematode C. elegans. We sought to determine if autophagy is important for genome stability during meiosis and found that the core adult C. elegans autophagy genes bec-1, atg-7, unc-51, and atg-18 were all required for proper meiotic development of oocytes. Loss of these …


Claiming The Right To Belong: Diversity And The Politics Of Inclusion In Queens, New York, Susan J. Tanenbaum Sep 2024

Claiming The Right To Belong: Diversity And The Politics Of Inclusion In Queens, New York, Susan J. Tanenbaum

Dissertations, Theses, and Capstone Projects

This dissertation examines social integration in a diverse civic and political mainstream. The social science research on intergroup contact in U.S. cities undergoing significant demographic change tends to focus on encounters between members of majority “in-groups” and minority “out-groups” in the context of workplaces, neighborhoods, and families. I contend that civic politics is another compelling strategic site for observing intergroup contact between emerging and established players. My study presents three cases of claims-making activity during the post-9/11 period in New York City’s borough of Queens, where close to 50% of the population is foreign-born and no single racial group predominates. …


Intuitionism, Justification Logic, And Doxastic Reasoning, Vincent A. Peluce Sep 2024

Intuitionism, Justification Logic, And Doxastic Reasoning, Vincent A. Peluce

Dissertations, Theses, and Capstone Projects

In this Dissertation, we examine a handful of related themes in the philosophy of logic and mathematics. We take as a starting point the deeply philosophical, and—as we argue, deeply Kantian—views of L.E.J. Brouwer, the founder of intuitionism. We examine his famous first act of intuitionism. Therein, he put forth both a critical and a constructive idea. This critical idea involved digging a philosophical rift between what he thought of himself as doing and what he thought of his contemporaries, specifically Hilbert, as doing. He sought to completely separate mathematics from mathematical language, and thereby logic. In chapter 3, we …


The Blackgirl Project: Examining The Impact And Manifestation Of Colorism Among Black Adolescent Girls In The United States: A Critical Participatory Action Research Approach, Gina (Diagou) R. Sissoko Sep 2024

The Blackgirl Project: Examining The Impact And Manifestation Of Colorism Among Black Adolescent Girls In The United States: A Critical Participatory Action Research Approach, Gina (Diagou) R. Sissoko

Dissertations, Theses, and Capstone Projects

Colorism is a skin tone stratification system that privileges lighter-skinned people over their darker-skinned counterparts. Although colorism remains surprisingly understudied, it has been linked to a variety of negative mental health and social outcomes. Colorism particularly impacts Black girls—particularly in adolescence. This dissertation utilized microaggressions theory and a critical participatory action research framework to describe (1) the manifestation of colorism in the lives of darker-skinned Black girls, (2) the impact of colorism on Black girls’ mental health, (3) the ways in which Black girls cope with and resist colorist experiences, and (4) create a taxonomy of colorist microaggressions. Ten Black …


Helpful Intentions? Impact Of Intentionality On Children's Memory For Forensically-Relevant Information, Ella P. Merriwether Sep 2024

Helpful Intentions? Impact Of Intentionality On Children's Memory For Forensically-Relevant Information, Ella P. Merriwether

Dissertations, Theses, and Capstone Projects

Rationale: When a child is a witness or victim of a crime, they are often asked a barrage of questions regarding when the crime took place, how many times it occurred, and how the abuse unfolded (Cross & Whitcomb, 2017; Sullivan et al., 2022). These questions can be problematic because they rely on concepts for which children may lack memory or linguistic ability to answer (Fenson et al., 2000; Friedman, 1993). One fundamental element missing from the copious research (e.g., Brubacher et al., 2012; Stolzenberg et al., 2017a; Wylie et al., 2021) on children’s ability to recount forensically-relevant information is …


Mechanism Of Host Recognition By The Bacteriophage Cystoviridae, Charles F. Robinson Iv Sep 2024

Mechanism Of Host Recognition By The Bacteriophage Cystoviridae, Charles F. Robinson Iv

Dissertations, Theses, and Capstone Projects

The Cystoviridae is a unique family of double stranded RNA bacteriophage that fuses its outer viral membrane with the lipopolysaccharide membrane of its Gram-negative host. In a series of studies, we determined the specifics of Cystoviridae host binding and the requirements of host fusion. The outer membrane vesicles (OMVs) secreted by the host inhibit Cystoviridae infection. We studied the interaction between OMVs and Cystoviridae to observe the host requirements for binding Cystoviridae. We determined that Cystoviridae strains Phi 8 and Phi 12 recognize the core polysaccharide and lipid A of the host lipopolysaccharide (LPS) for binding. The P6 protein …


Exploring The Correlation Between Google Trends And Crime Statistics: A Focus On Motor Vehicle Theft In The United States, Yu-Hsuan Liu Sep 2024

Exploring The Correlation Between Google Trends And Crime Statistics: A Focus On Motor Vehicle Theft In The United States, Yu-Hsuan Liu

Dissertations, Theses, and Capstone Projects

This dissertation examines the linear relationships between motor vehicle theft (MVT) estimates from Google Trends--a form of digital trace data--and official crime statistics, including the Uniform Crime Reports (UCR), National Crime Victimization Survey (NCVS), National Insurance Crime Bureau (NICB), National Incident-Based Reporting System (NIBRS), and 911 calls for service (CFS 911). It offers a comprehensive analysis of the limitations inherent in current crime statistics, discusses measurement errors, and explores statistical models to mitigate the impact of measurement error, applying these methods to validate Google Trends MVT data and other official MVT statistics. Furthermore, this study incorporates social disorganization theory and …


Building Networks, Producing Spaces For Play: Local Geographies And National Organizing In The History Of Adventure Playgrounds In The United States, 1949-1999, Reilly B. Wilson Sep 2024

Building Networks, Producing Spaces For Play: Local Geographies And National Organizing In The History Of Adventure Playgrounds In The United States, 1949-1999, Reilly B. Wilson

Dissertations, Theses, and Capstone Projects

This dissertation provides an historical analysis of repurposed material adventure playgrounds in the United States between 1949 and 1999. Three microhistories of adventure playgrounds (The Yard, in Minneapolis, M.N., and several playgrounds in New York City, N.Y., and Houston, T.X.) are framed against the wider socio-economic changes that shaped more than thirty-five adventure playgrounds in the United States over the period of study. By focusing on the relationships mobilized by adventure playground advocates at different scales and across different points of view, and how these networks shaped the local production of spaces for play, this dissertation's method underlines the importance …


Association Of Autistic Traits And Psychiatric Symptoms In Children With A Fragile X Premutation Allele: The Neurodevelopmental Profile, Ariel Zucker Sep 2024

Association Of Autistic Traits And Psychiatric Symptoms In Children With A Fragile X Premutation Allele: The Neurodevelopmental Profile, Ariel Zucker

Dissertations, Theses, and Capstone Projects

Throughout the lifespan, approximately 14% of males and 5% of females with a fragile X premutation (PM) (defined as 55-200 CGG repeats on the X-linked FMR1 gene) are diagnosed with Autism Spectrum Disorder (ASD). For individuals that do not meet diagnostic criteria for ASD, autistic traits (ATs) are often present in this population and have been shown to have a subtle and sub-clinical presentation of social communication and interaction deficits. While less is known about the phenotype of children with a PM, studies have found increased rates of ASD and ATs in adults with a PM allele compared to controls. …


Late-Life Depression: The Interplay Between Cerebrovascular Risk, Cortical And Subcortical Atrophy, And Treatment Response, Dakota Egglefield Sep 2024

Late-Life Depression: The Interplay Between Cerebrovascular Risk, Cortical And Subcortical Atrophy, And Treatment Response, Dakota Egglefield

Dissertations, Theses, and Capstone Projects

Late-life depression (LLD) is associated with poor response to antidepressant medication treatment, cognitive impairment, cerebrovascular disease, and brain changes both in white and gray matter. Of particular interest is the vascular subtype of LLD, vascular depression (VD). Although LLD and VD have received considerable research attention, there are still areas that must be further clarified to adequately characterize aspects of LLD and VD that provide valuable information for possible interventions. Such areas include a stronger understanding of the moderating role of brain atrophy and changes in cognition in treatment response in LLD. This dissertation consists of three separate studies aimed …


Perceptual Expectation, Rebecca Keller Sep 2024

Perceptual Expectation, Rebecca Keller

Dissertations, Theses, and Capstone Projects

You are currently seeing many things, and, hopefully, you are currently about to see many other things. Many of the things that you are about to see will not be surprising, because you expect to see them. Sometimes, though, when you expect to see one thing and are faced with another, that thing will look like the thing you expected it to be, and not like the thing it actually is. This dissertation is an attempt to get a handle on what is happening in the visual system in these instances. In particular, I am trying to figure out what …


Unpacking Normative Change: The United Nations At Its 60th Anniversary, Giovanna Marques Kuele Sep 2024

Unpacking Normative Change: The United Nations At Its 60th Anniversary, Giovanna Marques Kuele

Dissertations, Theses, and Capstone Projects

This dissertation explores the UN at its 60th anniversary at a critical juncture, with seven nested observations, to answer why normative change happens at the UN, when it is triggered, and which proposed changes are ultimately adopted. It argues that normative change at the UN is a result of multilevel political consensus at critical junctures. At the macro level, these junctures are triggered by global crises and international summits that provide a moment of normative reflection among the three UNs—member states, secretariat, and non-state actors—thereby increasing the likelihood of achieving multilevel political consensus. At the micro level, the formation of …


Challenging Beliefs: Examining The Efficacy Of Corrections For Conspiratorial And Partisan Misinformation, Ava Zwolinski Sep 2024

Challenging Beliefs: Examining The Efficacy Of Corrections For Conspiratorial And Partisan Misinformation, Ava Zwolinski

Dissertations, Theses, and Capstone Projects

The threat of misinformation is widely acknowledged among researchers and laypeople (NORC, 2021). When misinformation coalesces with conspiracy theories, the repercussions can be especially dangerous, sometimes even fatal. Events such as the January 6th insurrection and the Buffalo Tops Supermarket shooting were both, in part, inspired by misleading information and conspiracy theories (Burke, 2022; Dawsey, 2023). While misinformation involving conspiracy theories is recognized as possibly posing a greater threat to correction efforts (Lewandowsky, 2021a), no study has yet experimentally manipulated the presence or absence of conspiratorial elements within misinformation. This dissertation explores whether conspiratorial misinformation is more difficult to correct …


Design, Fabrication, And Spectroscopy Of Photocatalytic Materials In Visible Spectrum, Yamuna Paudel Sep 2024

Design, Fabrication, And Spectroscopy Of Photocatalytic Materials In Visible Spectrum, Yamuna Paudel

Dissertations, Theses, and Capstone Projects

Heterogeneous photocatalysis has attracted research interest in sustainable energy technologies. However, achieving high photocatalytic efficiency from visible light-absorbing semiconductors is challenging due to their weak absorption, transport losses, and low activity. While multilayer approaches have been developed to enhance the surface reactivity and stability independent of electronic factors, a comprehensive framework for optimizing light-matter interactions has not yet been established. Here, we introduce a photonic strategy using semiconductor metasurfaces, which is highly effective in enhancing the photocatalytic activity of GaAs, a high-performance semiconductor with a near-infrared bandgap. Our engineered pillar arrays with heights of ~150 nm exhibit Mie resonances near …


Preschoolers’ Generation Of Quantity Implicatures, André Eliatamby Sep 2024

Preschoolers’ Generation Of Quantity Implicatures, André Eliatamby

Dissertations, Theses, and Capstone Projects

This dissertation uses the developing child as a window into the mechanisms and representations that allow us to understand the meaning of utterances in their contexts. I present three studies investigating 4- and 5-year-olds’ ability to generate two types of “quantity implicatures,” classic scalar implicatures with some that imply not all, and free choice inferences that arise with sentences like “Larry is allowed to have cake or ice-cream.” Together, the studies suggest a close relationship between pragmatic development and word learning, something not appreciated in existing literature. In the first study investigating some, I show that preschoolers interpret …


Bodies For Catastrophe: A Montage Study Of Palestinian Digital Labor, Francisco Ramos Sep 2024

Bodies For Catastrophe: A Montage Study Of Palestinian Digital Labor, Francisco Ramos

Dissertations, Theses, and Capstone Projects

This thesis investigates Palestinian digital labor through the method of montage. Digital labor, understood as bodily activity transfigured by digital machines into exploitable information, is examined within the context of Israeli surveillance technologies used against Palestinians. The study critically explores the dual political functions of these technologies: as tools of settler-colonial domination aiming to dispossess Palestinians, and as neoliberal mechanisms seeking to profit from the surveillance of Palestinian bodies. The second half of the thesis turns to the ways Palestinians engage with such technologies and unsettle the economic and colonial logics embedded in them.

The research is structured nonlinearly using …


Moving Pictures Of The Past: Nostalgia For Classical Hollywood In The Broadway Musical, 1960–1990, Curtis Russell Sep 2024

Moving Pictures Of The Past: Nostalgia For Classical Hollywood In The Broadway Musical, 1960–1990, Curtis Russell

Dissertations, Theses, and Capstone Projects

In this dissertation, I examine how Broadway staged classical Hollywood between 1960 and 1990 amid social, artistic, and industrial upheaval. While upheaval and experimentation are constants even during epochs of apparent stability, the story my dissertation tells is of an industry facing the perils of obsolescence by looking backward and westward to understand how its larger and more powerful culture industry sibling navigated similar moments of disruption. Building on Fredric Jameson’s notion of the “nostalgia film,” I contend that between 1960 and 1990 the nine “nostalgia musicals” under consideration served the same function for the Broadway musical that the nostalgia …


Measuring Intersectional Strength And Stigma Among Racially Minoritized Gender Diverse Young Adults, Joseph Carter Sep 2024

Measuring Intersectional Strength And Stigma Among Racially Minoritized Gender Diverse Young Adults, Joseph Carter

Dissertations, Theses, and Capstone Projects

Background: Racially minoritized transgender and gender expansive young adults (RMTGEYA; aged 18-26) experience mental health inequities due to intersectional, multilevel stigma. RMTGEYA communities embody intersectional strength and resilience that can mitigate the impact of stigma. Understanding and capturing strength and stigma factors to address these inequities has significant implications for clinical science research and practice. There is, however, a complete absence of instruments that are validated to do so. Objective: The goal of this study is to conduct a three-phase, mixed methods study that centers intersectional and community engaged methods of psychometric development for a measure that captures daily experiences …


Loneliness And The Urban American (Non-)Romantic, Sarah C. Cook Sep 2024

Loneliness And The Urban American (Non-)Romantic, Sarah C. Cook

Dissertations, Theses, and Capstone Projects

Loneliness, also known as ‘perceived social isolation,’ is an increasingly common feeling among Americans. It can be critically unhealthy when chronic, and recent revelations about its health effects have garnered a significant amount of media attention. Although statistical evidence tells us that marriage is the strongest defense against loneliness, over a third of Millennials and Gen-Zers say marriage is outdated; and census data shows that living alone is both one of the fastest-growing demographics in America, as well as a relatively stable housing arrangement. After examining existing research and media reports on loneliness itself in some depth, including factors that …


Building Black Manhattan: Architecture, Art, And The Politics Of Respectability, 1857–1914, Jessica Larson Sep 2024

Building Black Manhattan: Architecture, Art, And The Politics Of Respectability, 1857–1914, Jessica Larson

Dissertations, Theses, and Capstone Projects

“Building Black Manhattan” is the first study to examine the architectural contributions of Black women reformers to the urban development of New York City between the Civil War and the Great Migration. Through the construction of charitable and reform institutions throughout Manhattan, they articulated a strategy of racial uplift through deliberate spatial construction.

As reform work was one of the very few arenas in the nineteenth and early twentieth centuries in which women had a significant public voice, the buildings constructed to facilitate reformers’ work encoded the social, racial, and gendered demands of women into their designs. These institutions included …


Repurposing Bt-11 To Treat Alzheimer’S Disease: Exploring The Glutathione-S-Transferase Lancl2 As A Target, Emily Birnbaum Sep 2024

Repurposing Bt-11 To Treat Alzheimer’S Disease: Exploring The Glutathione-S-Transferase Lancl2 As A Target, Emily Birnbaum

Dissertations, Theses, and Capstone Projects

Approximately 99.6% of potential Alzheimer’s drugs fail, thus developing successful drugs is a high priority. The failure at developing successful drugs relates to the complex nature of the disease itself. Many components act together to trigger a cascade that ultimately results in neurodegeneration and cognitive dysfunction associated with the disease. In building a multiplex model of Alzheimer’s it is important to understand its specific biological mechanisms. One of these key pathological mechanisms is neuroinflammation. Understanding the pathways involved in neuroinflammation in Alzheimer’s is an urgent need, as it poses a promising avenue for future effective therapeutics. Specifically, as many investigational …


Retinoblastoma Malignance And Exosome Mechanisms Facilitating Optic Nerve Head Metastatic Niche Formation, Cui Shi Sep 2024

Retinoblastoma Malignance And Exosome Mechanisms Facilitating Optic Nerve Head Metastatic Niche Formation, Cui Shi

Dissertations, Theses, and Capstone Projects

Retinoblastoma (RB) is a rare pediatric ocular tumor that occurs before five years of age and it is the most common intraocular cancer of childhood with more than 300 children in the United States and 8000 diagnosed globally each year. RB arises from the proliferation of cone photoreceptor precursor cells in the retina as a result of mutations in the RB1 gene. The influence of RB secreted factors on cells in the retinal environment has not been fully elucidated. Cancer cell released exosomes have been shown to transform their microenvironment through transfer of metastasis promoting molecular cargo. Cancer cell extracellular …


The Film, The Stadium And The Jail: The Post-Industrial Transformation Of Downtown Durham, Seth Rose Sep 2024

The Film, The Stadium And The Jail: The Post-Industrial Transformation Of Downtown Durham, Seth Rose

Dissertations, Theses, and Capstone Projects

By the late 1980s, Durham, North Carolina’s downtown-based industrial economy had been replaced by a powerful knowledge economy in the city’s peripheries. Downtown Durham’s vast array of tobacco and textiles manufacturing buildings stood empty, along with most of its commercial spaces, offices and sidewalks. This thesis argues that the local development of two major public works, a baseball stadium (the Durham Bulls Athletic Park) and a jail (the Durham County Detention Center), conceived and constructed on similar timelines in close physical proximity, was indicative of how—and for whom—city and county officials envisioned a revitalized downtown. The first chapter examines the …


The Effects Of Environmental Changes On The Biodiversity And Macroecological Patterns Of Bird Assemblages In The United States, Marlen Acosta Alamo Sep 2024

The Effects Of Environmental Changes On The Biodiversity And Macroecological Patterns Of Bird Assemblages In The United States, Marlen Acosta Alamo

Dissertations, Theses, and Capstone Projects

The current restructuring of species assemblages and global loss of biodiversity result from species-specific responses to anthropogenic changes in climate and land cover. I investigated the effect of these two drivers on the seasonal distribution and biodiversity of birds in the United States and how human-induced habitat loss impacts macroecological patterns such as the species-area and the abundance-occupancy relationships. In Chapter 1, I examined the existence of a correlation between breeding and wintering geographic distributions of birds with different migratory strategies and the effect of changes in climate and the proportion of crop-pasture and urban land cover on this correlation. …


A Machine Learning Approach To Discovering Physical Models Of Galaxy Formation, Festa Bucinca Sep 2024

A Machine Learning Approach To Discovering Physical Models Of Galaxy Formation, Festa Bucinca

Dissertations, Theses, and Capstone Projects

Galaxies are the breathtakingly beautiful starry islands of the Universe. The process of galaxy formation involves the transformation from simple initial conditions in the early Universe to the complex galaxy structures we observe today. Spanning an immense spatial range and tremendous time scales - from the vastness of the Universe to the scale of individual stars - the physics of galaxy formation is both complex and crucial for understanding the Universe we live in. However, despite significant advancements, our theoretical understanding of galaxy formation remains incomplete.

In the era of big data available from hydrodynamical simulations and observations, Machine Learning …


Structural Insights Into Bacterial Helicase Loading At A Replication Origin By Cryogenic Electron Microscopy, Abhipsa Shatarupa Sep 2024

Structural Insights Into Bacterial Helicase Loading At A Replication Origin By Cryogenic Electron Microscopy, Abhipsa Shatarupa

Dissertations, Theses, and Capstone Projects

DNA replication is a meticulously regulated and intricate process crucial for cellular viability. Replicative helicases, essential for unwinding DNA during replication, rely on helicase loader proteins for efficient loading and assembly at replication origins. In Escherichia coli, the replicative helicase DnaB forms a complex with six copies of the bacteriophage Lambda λP loader, resulting in a B6P6 conformation. The conformation of the BP complex, with a 6:6 stoichiometry, indicates that the isolated DnaB is initially captured by λP (B6P6) through its carboxy-terminal domain lassos/grappling hooks, serving as an early intermediate before transitioning …


Variability In Associations Among Seabirds And Marine Mammals: Causes And Consequences, Samantha A. Monier Sep 2024

Variability In Associations Among Seabirds And Marine Mammals: Causes And Consequences, Samantha A. Monier

Dissertations, Theses, and Capstone Projects

Marine predators today face multifaceted stressors from changing climate to changing prey availability, and these changes are occurring at unprecedented speeds. Any alteration to a species’ environment has the potential to disrupt social networks and thus, how animals obtain and transfer information. Interspecific social interactions in the form of local enhancement and facilitation are a critical, but not yet well-understood, component of seabird foraging; of immediate concern is that anthropogenic changes may be altering the quantity and quality of positive species interactions, with consequences for the species involved.

While we know these interactions are not immutable, less is known about …