Digital Commons Network^™

The Anaerobic Rose Chamber (Arc): Novel Applications For Probing Clostridioides Difficile Dynamics, Tatiana Zvonareva

Chemistry & Biochemistry Theses & Dissertations

Clostridioides difficile infection (CDI) is an urgent public health threat with a high rate of recurrence and limited treatment options. Caused by the anaerobic intestinal pathogen C. difficile, this disease affects up to 500,000 Americans annually. Despite progress in our understanding of CDI pathophysiology, the lack of effective and accessible experimental platforms compatible with obligate anaerobe physiology hinders the advancement of treatment therapy. The application of in vivo models has been indispensable in understanding CDI pathophysiology, probing the complexity of the host response to the microbe, and establishing treatment protocols, and it continues to be essential in preclinical testing. …

Pedestrian-Motorist Self-Reported Behavioral Intentions Toward Using Alternative And Standard Safety Infrastructure, Emma Sunshine Hood

Psychology Theses & Dissertations

The increasing trend in pedestrian-motorist incidents on American roadways warrants a novel solution for improving roadway safety. Alternative crosswalk designs have piqued communities both in the United States and abroad. Designs range from slight changes in colors to extravagant illusions of the roadway falling beneath users. These crosswalk designs are not novel, literature on their efficacy as safety infrastructure is modest with mixed results. The purpose of the study was to expand the current literature on alternative crosswalk designs. The author hypothesized that the differences in behavioral intentions at alternative and standard safety infrastructure would be greater for younger male …

An Examination Of Food And Alcohol Disturbance Based On Sexual Orientation In A Sample Of Women Who Binge Eat, Alicia M. Moulder

Psychology Theses & Dissertations

Food and alcohol disturbance (FAD), characterized by disordered eating behaviors in the context of drinking alcohol to enhance intoxication, counteract alcohol’s calories, or both, is associated with increased risk of negative drinking consequences. Previously established as a phenomenon occurring in college students, research has begun to support that FAD may also occur in nonstudents. Three particularly vulnerable groups for FAD may include women, individuals with history of binge eating, as well as sexual minority individuals. Consequently, the goals of the current study were to elucidate differences in FAD engagement between sexual minority women (SMW) and heterosexual women using a sample …

One-Year Limb Salvage And Quality Of Life Following Mechanical Aspiration Thrombectomy In Patients With Acute Lower Extremity Ischemia, Alex Powell

All Publications

Objective: Lower extremity acute limb ischemia (LE-ALI) is associated with high morbidity and mortality rates, and a burden on patient quality of life (QoL). There is limited medium- to long-term evidence on mechanical aspiration thrombectomy (MT) in patients with LE-ALI. The STRIDE study was designed to assess safety and efficacy of MT using the Indigo Aspiration System in patients with LE-ALI. Thirty-day primary and secondary endpoints and additional outcomes were previously published. Here, we report 365-day secondary endpoints and QoL data from STRIDE.

Methods: STRIDE was a multicenter, prospective, single-arm, observational cohort study that enrolled 119 patients across 16 sites …

It Takes A Village: Investigating How Community And Cultural Factors Foster Resilience In Latine Immigrant Families, Mara Makasiar

Dissertations (1934 -)

Latine immigrants constitute the largest group of non-U.S.-born individuals in the United States and face heightened risks including poverty, inadequate healthcare, discrimination, and acculturation-related stressors. Despite these challenges, many demonstrate resilience, achieving positive outcomes for themselves and their children. This study investigated how community and cultural factors foster resilience in Latine immigrant families, addressing a gap in understanding protective mechanisms beyond individual and family levels. Using a mixed-methods approach, quantitative analyses (N=89) revealed that immigration-related stress significantly predicted caregiver mental health problems (β = 0.35, p < .01), while financial satisfaction emerged as a protective factor (β = -0.35, p < .01). For youth, ethnic identity predicted prosocial behaviors (β = 0.35, p < .01), and emotion regulation consistently predicted self-esteem (β = 0.40, p < .01) and mental health problems (β = -0.54, p < .01). Contrary to hypotheses, community factors (collective efficacy, religious social capital) and cultural cohesion did not significantly predict outcomes beyond individual and family factors. Qualitative interviews (n=30) provided context, revealing themes of resource access barriers, multifaceted support systems, cultural maintenance, and community involvement. These findings highlight the complex interplay of factors influencing resilience in Latine immigrant families and underscore the need for more nuanced measures of community and cultural influences. The study contributes to a more comprehensive understanding of resilience processes in this population, with implications for developing culturally sensitive interventions and policies to support Latine immigrant families' well-being.

Stability Of The S-N Bond In S-Nitrosothiols: Computational And Experimental Approach, Rustam Sabitov

Dissertations (1934 -)

S-Nitrosothiols (RSNOs) are chemical compounds capable to transport nitric oxide (NO) and show promise in the treatment of cardiovascular diseases. RSNOs occur naturally in-vivo, and others have been synthesized in-vitro as potential drug candidates for NO transport and release. However, RSNOs are inherently unstable due to their weak S–N bond (D0(S-N)=25–30 kcal/mol), so developing a deeper understanding of the factors influencing the RSNOs stability is crucial. In Chapter 2, we investigated the substituent effect on the -SNO group properties. Substituting R– in RSNOs with more electro-donating character can stabilize the –SNO group according to the Natural Resonance Theory (NRT). But …

The Voices Of Thriving Black Women In Milwaukee: An Exploration Of Narrative Identity And Psychosocial Well-Being, Jessica Krukowski

Dissertations (1934 -)

There is a dearth in research regarding the narrative identities of Black women. Narrative identity is an individual’s internal story that evolves and transforms as one encounters new experiences and adopts new viewpoints. It is a person’s reconstructed past and imagined future, providing one’s life a degree of coherence and meaning. The present study is part of a larger project (N=79) that employed the Modified Life Story Interview; a semi-structured way for collecting one’s self-defining life story. Participants from the larger project also completed measures of psychosocial well-being. For the present strength-based study, only those participants with the highest psychosocial …

Determining The Differentially Expressed Genes By Bayesian Decision Rule, Tao Cui

Dissertations (1934 -)

dentification of differentially expressed genes (DEGs) is crucial for understanding the molecular mechanisms underlying various biological conditions and diseases. Traditionally, this process utilizes statistical methods which manage high-dimensional data and adjust for multiple testing to ensure statistical and biological relevance. These methods assume the independence of genes, which is not usually the case, many of genes are correlated when there is a stimilation. In this dissertation, we will work on the methods that consider the correlation in finding the DEGS to improve the power of tests. We have developed a novel approach to multiple hypothesis testing using Bayesian decision rules …

Self-Management, Attitudes, And Barriers For Students With Common Food Allergies Utilizing Campus Dining At A Large Urban University, Samantha Dahlberg, Ashwini Wagle, Jacqueline Bergman

Faculty Research, Scholarly, and Creative Activity

Food allergies are associated with stress and anxiety in college students. This research study aims to explore the findings of students with known food allergies and their perspectives on how one large urban university campus dining service accommodates their dietary needs. The study utilized a mixed-methods approach, and a non-probability, purposive sampling was used for a campus-wide online self-reported survey from August to October 2023. The survey included twenty close-ended and open-ended questions about the student’s food allergy attitudes, self-management, and barriers to on-campus dining services. Participants were students who self-identified with a medically diagnosed food allergy or intolerance and …

Lawyers' Rare Privilege Of Litigating In The Media, Douglas Richmond

Penn State Law Review (2003 - Present)

No abstract provided.

Crisis Standards Of Care And Triage: Medico-Legal Conundrums, George P. Smith Ii

Penn State Law Review (2003 - Present)

No abstract provided.

Booze On The Loose: A Critique Of Washington State's Liquor Privatization, Brooks Inciardi

Penn State Law Review (2003 - Present)

No abstract provided.

Where Is My Cargo?: When A Force Majeure Clause Should Not Be An Excuse For International Shipping Delays And Non- Delivery, Yujin Jang

Penn State Law Review (2003 - Present)

No abstract provided.

Unreasonable, Unfair, And Unaccountable: What Commonwealth V. Pownall Reveals About Instructing Juries On Police Use Of Deadly Force, Jennifer Bauer

Penn State Law Review (2003 - Present)

No abstract provided.

A New Era Of Deference: From Chevron To Loper Bright, Daniel E. Walters

Faculty Scholarship

Deference to administrative agencies’ interpretations of ambiguous statutory provisions has been a hallmark of administrative law and regulatory policy for the past forty years. The Supreme Court recently upended that settled allocation of power between agencies and courts, granting interpretive primacy to courts even where statutes essentially require policy choices. However, questions remain about precisely how courts will exercise this policymaking authority that agencies used to exercise, as well as about the multiple “offramps” from this nondeferential standard that the Court left open. Rather than a new era of nondeference, it is just as likely we are embarking on a …

Employing Expressive Art To Explore Mexican Americans’ Grief Experiences Of Loss Due To Covid-19, Leyla Feize, Varesh Gorabi, Vanessa Garza, Christian Baggett, Cassandra Sarmiento, Margarita Tirado, Angela Maldonado, Melissa Daniels

School of Social Work Faculty Publications

The COVID-19 pandemic changed people’s lives and resulted in tremendous pain, loss and suffering. The Rio Grande Valley (RGV), in the state of Texas in the U.S., was one of the regions with the highest number of infections and deaths during the pandemic. However, individuals’ bereavement in the RGV is rarely addressed. In this qualitative study, a snowball sample of 47 individuals who had lost their loved ones during the years 2020–2021 were interviewed and invited to engage in an art activity. The findings revealed four themes: peculiar funeral, grieving confusion, loved ones’ memories, and connection to self and the …

Late Life Cognitive Function Trajectory Among The Chinese Oldest-Old Population-A Machine Learning Approach, Jierong Hu, Minzhi Ye, Juan Xi

School of Social Work Faculty Publications

Informed by the biopsychosocial framework, our study uses the Chinese Longitudinal Healthy Longevity Survey (CLHLS) dataset to examine cognitive function trajectories among the oldest-old (80+). Employing K-means clustering, we identified two latent groups: High Stability (HS) and Low Stability (LS). The HS group maintained satisfactory cognitive function, while the LS group exhibited consistently low function. Lasso regression revealed predictive factors, including socioeconomic status, biological conditions, mental health, lifestyle, psychological, and behavioral factors. This data-driven approach sheds light on cognitive aging patterns and informs policies for healthy aging. Our study pioneers non-parametric machine learning methods in this context.

Occurrence, Abundance, And Formation Of Atmospheric Tarballs From A Wide Range Of Wildfires In The Western Us, Kouji Adachi, Jack E. Dibb, Joseph M. Katich, Joshua P. Schwarz, Hongyu Guo, Pedro Campuzano-Jost, Jose L. Jimenez, Jeff Peischl, Christopher D. Holmes, James Crawford

Faculty Publications

Biomass burning emits large numbers of organic aerosol particles, a subset of which are called tarballs (TBs). TBs possess a spherical morphology and unique physical, chemical, and optical properties. They are recognized as brown-carbon aerosol particles, influencing the climate through the absorption of solar radiation. Aerosol particles were collected from wildfire and agricultural-fire smoke sampled by NASA's DC-8 aircraft during the Fire Influence on Regional to Global Environments and Air Quality (FIREX-AQ) campaign in the western US from July to September 2019. This study developed an image analysis method using deep learning to distinguish TBs from other round particles that …

Pacific Rxtracts - October 2024, Pacific Rxtracts

Pacific RxTracts

Articles

1. First Nasal Spray for Anaphylaxis Approved
2. Statins: The Unexpected Therapeutic Benefits You Didn’t Know About
3. Is COVID Driving Us Mad? The Mental Toll on the Unvaccinated vs. Vaccinated
4. Acetaminophen’s Effects on Positive Empathy
5. Semaglutide: More Than Meets The Eye
6. RSV: Complications and New Therapies
7. Contribution of Calcium Channel Blockers and Selective Serotonin Reuptake Inhibitors to the Risk of Fractures

Superintendents’ Perceptions Of Strategies For Implementing Social Justice Leadership For Diverse Student Populations, Stefani Mcdade Morrow

Electronic Theses and Dissertations

The purpose of this qualitative study was to explore superintendents’ perceptions of implementing social justice leadership strategies within their K-12 school systems. The study sought to identify how superintendents leveraged the components of social justice leadership in the pursuit of equity for diverse student populations. The researcher conducted the study using interpretive phenomenological analysis methodology to examine the lived experiences of eight Texas superintendents with experience leading equity-focused agendas in their respective districts. The study’s participants included superintendents with experience ranging from 18 months to 16 years, representing districts from small rural areas to major suburban regions. Each participant engaged …

Transatlantic Literary Networks, 1949-1972, Cristina Iuli, Stefano Morello

Publications and Research

Il racconto di Donald Barthelme “Critique de la Vie Quotidienne”, pubblicato sul New Yorker il 9 luglio 1971, si apre su una famiglia newyorkese di classe media sull’orlo di una crisi matrimoniale. Wanda, la moglie, sfoglia Elle, costringendo il marito a prestare attenzione alle foto dell’elegante ristrutturazione di un vecchio mulino in Bretagna da cui spiccano arredi di Arne Jacobsen e “cose di plastica arancione e rosso brillante che arrivano da Milano” (Barthelme 1971, p. 26). Barthelme, che aveva trascorso tutta l’infanzia e buona parte della gioventù a Houston, in Texas, dove il padre era direttore del museo di …

Administrators And Teachers' Experiences With Trauma Training And Trauma Informed Care, Pamala Patterson

Electronic Theses and Dissertations

Trauma problems have made an impression on school systems in the United States, and parents, students, administrators, and teachers pose concerns in the community and schools. The purpose of this study was to understand the lived experiences of administrators and teachers on trauma training and the implementation of trauma-informed care. This qualitative method was hermeneutical-phenomenological and centered on the lived experiences of this population. The researcher analyzed individual interviews of 11 educators identified as administrators and teachers. The results indicated that this population was disadvantaged by the trauma training they received in their ability to provide trauma-informed care. Three themes …

Meridians 23:2, Ginetta Candelario

Meridians: Feminism, Race, Transnationalism

No abstract provided.

Standing At The Crossroads: An Analysis Of The Circuit Split Over Ada Tester Standing, Jennifer Tedisco

Cardozo Journal of Equal Rights & Social Justice

This Article analyzes the circuit split concerning whether self-appointed testers without intent to travel or book a reservation have Article III standing to sue hotels forfailing to disclose accessibility information on their websites in violation of an Americans with Disabilities Act ("ADA") regulation. This Article ultimately argues that these testers should have standing under an informational injury and/or stigmatic injury rationale. However, negative perceptions ofADA testers coupled with the Supreme Court's recent standing decisions haveput the private enforcement of the ADA and other disability rights statutes in jeopardy. In hopes ofpreserving the ability oftesters to bring suit against hotels and …

Assess Weed Population Density, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

The most accurate way to estimate the weed population of a paddock is to count the number of plants in an area of known size at numerous locations.

Use a quadrant, which may be square or circular, to carry out weed plant counts. The number and location of counts needed to estimate the weed population will vary depending on the distribution pattern.

Canola – Essentials For Growing A Successful Crop, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Ensuring the basics of canola agronomy are followed can minimise the financial risk of growing canola, which can be higher than other crops due to high input costs, particularly seed and fertiliser.

Barley Leaf Diseases And Their Management, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Barley leaf diseases such as scald, net blotches (net form and spot form), powdery mildew, ramularia leaf spot, leaf rust, and barley yellow dwarf virus, and cereal yellow dwarf virus can reduce yield and grain quality. Correct identification is important in disease management, as diseases differ in their best management strategies.

Hay Production, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

There are specific requirements for hay for the export market that are different to usual on-farm requirements. These include earlier cutting times, green hay colour, low moisture content, freedom from weeds, and thin-strawed varieties.

Some oat varieties do not meet the exporter’s standard and therefore will not be accepted for delivery. Growers interested in the export market should check with individual exporters for their requirements.

Variety information can be found in the department’s current Western Australian crop sowing guide, available on the website at dpird.wa.gov.au.

Insect Pests And Their Management In Oats, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Field pests

Damage from invertebrate pests is generally not a major factor for oat crops, however there is a zero tolerance to live pests in export hay.

Significant damage can occur if pest populations build up. Planning rotations to minimise pest carryover, timely sowing, adequate crop nutrition, and good control of weed and root diseases will assist in reducing the likelihood of crop damage by insect pests. Check crops regularly throughout their growth for field insects.

• Control redlegged earth mite and lucerne flea during the seedling stage if necessary.

• Aphids should be checked for and controlled from flag …

Factors Affecting Herbicide Performance, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Herbicide performance can vary greatly depending on factors including compatibility of herbicides, water quality, sprayer decontamination, and controlling stressed weeds. This page outlines these issues and demonstrates how to assess herbicide performance to achieve the best from your herbicides.