Digital Commons Network^™

Obo Foundry Food Ontology Interconnectivity, Damion Dooley, Liliana Andres-Hernandez, Georgeta Bordea, Leigh Carmody, Duccio Cavalieri, Lauren Chan, Pol Castellano-Escuder, Carl Lachat, Fleur Mougin, Francesco Vitali, Chen Yang, Magalie Weber, Hande Kucuk Mcginty, Matthew Lange

Faculty Research 2024

No abstract provided.

Machine-Guided Design Of Cell-Type-Targeting Cis-Regulatory Elements., Sager J Gosai, Rodrigo Castro, Natalia Fuentes, John C Butts, Kousuke Mouri, Michael Alasoadura, Susan Kales, Thanh Thanh L Nguyen, Ramil R Noche, Arya S Rao, Mary T Joy, Pardis C Sabeti, Steven K Reilly, Ryan Tewhey

Faculty Research 2024

Cis-regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing and stimulus responses, which collectively define the thousands of unique cell types in the body1–3 . While there is great potential for strategically incorporating CREs in therapeutic or biotechnology applications that require tissue specificity, there is no guarantee that an optimal CRE for these intended purposes has arisen naturally. Here we present a platform to engineer and validate synthetic CREs capable of driving gene expression with programmed cell-type specificity. We take advantage of innovations in deep neural network modelling of CRE activity across three cell types, efficient in silico …

Nsu Library Link - Fall 2024 - Volume 1.1 - The Inaugural Issue, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

Nsu Kpcom Link - Fall 2024 - Volume 3.3, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

Natasha, Pierre, & The Great Comet Of 1812, Otterbein Theatre And Dance Department

2024-2025 Season Productions

No abstract provided.

The Importance Of Being Earnest, Otterbein Theatre And Dance Department

2024-2025 Season Productions

No abstract provided.

Investigating The Impact Of Nmdar Loss On The Maturation Of Somatostatin Interneurons In Mpfc Of The Mouse Brain, Muhammed Shalan, Zoya Fazal, Gülcan Akgül, Natalia De Marco Garcia

Expo Student Presentations

2024 Fall Expo Online Poster Presentation

• Biological & Life Sciences

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Stigma In Interactions Between Adolescents With Functional Seizures (Fs) And Healthcare Providers, Arzoo Charania, Shujiya Fatima, Caroline Watson, Aaron D. Fobian

Expo Student Presentations

2024 Fall Expo Online Poster Presentation

• Social & Behavioral Sciences

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Go to article

Como Las Guardianas De Semillas En La Región De Arica Y Parinacota Están Recuperando El Derecho De La Soberanía Alimentaria, Emilia Bois

Chile: Cultural Identity, Social Justice, and Community Development

Both small farmers and industrial farmers provide us with our food, and we depend on them to feed us. As citizens, we should have the right to feed ourselves in a nutritious, sustainable, and culturally appropriate manner. This right is the right to food sovereignty, and we lost it when the government encouraged farmers to seek economic success rather than the health and well-being of all. In order not to depend on the government for nutritious, sustainable, and culturally appropriate food, we need to find other ways to be self-sufficient in our food supply. The agricultural practice of seed saving …

Neurosteroids For The Treatment Of Major Depressive Disorder (Mdd) And Chronic Pain (Paper), Meghan Haan

Honors Capstone Projects

Neurosteroids are endogenous steroids within the brain that act as modulators in neurotransmission. Among their targets are the gamma-aminobutyric acid (GABA) receptors, which are responsible for inhibitory signaling in the brain. The interaction between neurosteroids and GABA receptors is complex, influencing mood regulation and pain perception. Endogenous neurosteroids have been used in conditions such as postpartum depression (PPD), where fluctuation in neurosteroid levels contribute to the onset of depressive systems. Conversely, exogenous neurosteroids, such as brexanolone and zuranolone, have emerged as therapeutic agents for PPD. These compounds act as positive allosteric modulators (PAMs) on GABA receptors, enhancing inhibitory neurotransmission and …

Implied Occlusion And Subset Underestimation Contribute To The Weak-Outnumber-Strong Numerosity Illusion, Eliana G. Dellinger , '25, Katelyn M. Becker , '25, Frank H. Durgin

Psychology Faculty Works

Four experimental studies are reported using a total of 712 participants to investigate the basis of a recently reported numerosity illusion called “weak-outnumber-strong” (WOS). In the weak-outnumber-strong illusion, when equal numbers of white and gray dots (e.g., 50 of each) are intermixed against a darker gray background, the gray dots seem much more numerous than the white. Two principles seem to be supported by these new results: 1) Subsets of mixtures are generally underestimated; thus, in mixtures of red and green dots, both sets are underestimated (using a matching task) just as the white dots are in the weak-outnumber-strong illusion, …

Calculating Canola Seeding Rate And Recording Sheet, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Canola seeding rate needs to be high enough to get a good establishment to set up the crop for its potential yield and provide insurance against slugs, mites, disease, and other seeding issues. However, there is no point spending more on seed than needed.

This is the companion page for the online Canola seeding rate calculator, which enables you to calculate the seed rate you require for your target plant density.

Control Small Weeds In Crops, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

In an integrated weed management program, control of weeds should occur in the fallow, pre-sowing, early post-emergent, and in-pasture phases. Weed control can be achieved through killing weeds (particularly seedlings) with cultivation, herbicides, targeted weed control in wide-row cropping, targeted control of small patches of weeds, and biological control tactics.

Stockfeed Labelling In Western Australia, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

The Department of Primary Industries and Regional Development (DPIRD) is responsible for regulating the labels of stockfeed supplied in Western Australia (WA) to ensure they provide the required information to people feeding it to their livestock. This factsheet contains information to help stockfeed retailers and manufacturers meet WA’s labelling requirements.

Field Pea – Essentials For Growing A Successful Crop, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

This factsheet provides essential management practices for growing a successful field pea crop.

Managing Frost Risk, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Frost occurs on clear nights in early spring when the air temperature drops to 2°C or less. Crop damage from frost may occur at any stage of development but is most damaging at or around flowering.

Frost is difficult to manage, and damage will be unavoidable in some seasons. Risk management options proven to reduce frost risk include paddock zoning, crop and variety selection, time of sowing, stubble management and managing inputs. The greatest gains result from in paddock choice/zoning, crop and variety choice, and manipulating the canopy.

Zadoks Growth Scale, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Zadoks growth scale is a 0-99 scale of development that is recognised internationally for research, advisory work, and farm practice, particularly to time the application of chemicals and fertilisers.

Estimating The Size Of Retained Canola Seed, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

The size of canola seed (or number of seeds per kilogram) is essential in calculating the seeding rate for the crop. The rate needs to be high enough to get good establishment and protect against pests, diseases, or other seeding issues.

To work out the seeding rate, the seed size or number of seeds per kilogram. This can be easily calculated by farmers who retained seed.

Masthead

UC Law Constitutional Quarterly

No abstract provided.

Editor-In-Chief’S Foreword, Megan Stupi

UC Law Constitutional Quarterly

No abstract provided.

The Ninth Circuit’S Rfra Standard Of “Substantial Burden” As Applied To Native American Sacred Sites, Erik Renner

UC Law Constitutional Quarterly

This paper focuses on the Ninth Circuit’s understanding of the “substantial burden” standard under RFRA as it is applied to Native American sacred site cases. This paper looks at the old Ninth Circuit’s standard as set out in Navajo Nation, and its new standard as set out in Apache Stronghold. By understanding how the courts, specifically the Ninth Circuit, have limited their definition of the “substantial burden” under RFRA in sacred site cases, this paper will argue that the standard should be expanded to include “preventing religious exercise.” This expansion of what is a “substantial burden” under RFRA will better …

Cultural Perspectives On Psychoactive Substances: A Study Of Psilocybin In Indonesia, Parmis Mazdeh

Indonesia: Arts, Religion, and Social Change

This study examines the various cultural views on psilocybin in Indonesia, emphasizing its role in religious, spiritual, and cultural contexts. It investigates both the historical and present-day use of psychoactive substances, specifically psilocybin, in connecting with the divine, attaining transcendental enlightenment, and shaping identity within specific civilizations. Although psilocybin is illegal in Indonesia, these mushrooms can be found in the Gili Islands, raising questions about how they fit into local spiritual traditions and the legal loopholes that allow their use. Field research in the Gili Islands reveals how religious beliefs and practices influence the cultural acceptance of magic mushrooms, while …

The Icelandic Prevention Model Evaluation Framework And Implementation Integrity And Consistency Assessment, Michael J. Mann, John P. Allegrante, Megan L. Smith, Inga Dora Sigfusdottir, Alfgeir L. Kristjansson

Public and Population Health Faculty Publications and Presentations

The Icelandic Prevention Model (IPM) follows a systematic but flexible process of community capacity building, data collection, analysis, dissemination, and community-engaged decision-making to guide the data-informed selection, prioritization, and implementation of intervention strategies in preventing adolescent substance use. This paper describes two new evaluation tools intended to assess the: 1) integrity of IPM implementation, and 2) unique aspects of IPM implementation in different community contexts. These evaluation tools include a: 1) five-phase IPM Evaluation Framework for Assessing Value Across Communities, Cultures, and Outcomes (IPM-EF); and 2) 10-Step IPM Implementation Integrity and Consistency Assessment (IPM-IICA) that utilizes both …

In The Face Of God: Analyzing The Influence Of Religion On Social Dynamics And Cultural Preservation In Pniël, Joohee Na

South Africa: Multiculturalism and Human Rights

This research paper examines the role of religion in fostering community cohesion, cultural preservation, and governance in Pniël, a small South African town with deep historical and religious roots. Drawing on interviews with community members, it explores how religious practices and spaces function as mechanisms for maintaining collective identity, transmitting values across generations, and addressing social challenges like modernization and gentrification. The study highlights the interplay between tradition and change, emphasizing the importance of preserving religious heritage and cultural narratives in a secularizing world. It also discusses the implications of these findings for safeguarding the histories and identities of small …

Breast Cancer Screening In Yaoundé, Cameroon: Practices, Awareness, And Perceptions, Tianna Kidd

Cameroon: Development and Social Change

Abstract

Breast cancer is one of the leading causes of death worldwide, yet detection and treatment centers are not always widely available. This research project aims to assess the awareness and perceptions of breast cancer screening practices among women in Cameroon through observing healthcare centers in Yaoundé and conducting interviews with health professionals and a randomized selection of women. The main objective of the study was to identify the resources available for breast cancer screening in Yaoundé and to examine the barriers to breast cancer screening and treatment. Furthermore, the research investigates the available detection devices for breast cancer, particularly …

Ontology Design Facilitating Wikibase Integration — And A Worked Example For Historical Data, Cogan Shimizu, Andrew Eells, Seila Gonzalez, Lu Zhou, Pascal Hitzler, Alicia Sheill, Catherine Foley, Dean Rehberger

Computer Science and Engineering Faculty Publications

Wikibase – which is the software underlying Wikidata – is a powerful platform for knowledge graph creation and management. However, it has been developed with a crowd-sourced knowledge graph creation scenario in mind, which in particular means that it has not been designed for use case scenarios in which a tightly controlled high-quality schema, in the form of an ontology, is to be imposed, and indeed, independently developed ontologies do not necessarily map seamlessly to the Wikibase approach. In this paper, we provide the key ingredients needed in order to combine traditional ontology modeling with use of the Wikibase platform, …

Birthdays Without You, Natasha Ng, Special Collections, Fleet Library

11th Baker & Whitehill Student Artists' Book Contest 2025

Entry for the 11th Baker & Whitehill Student Artists' Book Contest. Opening reception and award ceremony Wednesday, February 19, 2025 at 6:30pm, Fleet Library, Main Reading Room. Juror: Roger S. Williams.

Issue 11: Pulmonary & Critical Care Insider, Bharat Bajantri Md, Sarah Ellsworth-Hoffman Mls, Dustin D. Linn Pharmd, Payal Shukla Md, Ms, Patricia Rich Md, Morgan Crites Np-C

Critical Care & Pulmonary

Pulmonary & Critical Care Insider Issue 11

Compiled by Bharat Bajantri, MD, and librarian Sarah Ellsworth, MLS for the clinicians of the Pulmonary and Critical Care team of Parkview.

The Pulmonary & Critical Care Insider newsletter was created by Dr. Bharat Bajantri, MD and Sarah Ellsworth, MLS in 2023 as a form of current awareness for current practice at our hospital, Parkview Health.

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Topics:

VIEWPOINTS:

Blood Pressure Measurement

Home Noninvasive Ventilation

ORIGINAL STUDY SUMMARY

Acute Pulmonary Embolism

The PEXIVAS trial

Respiratory Failure in hemorrhagic shock

SNAPSHOTS:

RBC Transfusions

New Small cell lung cancer Treatment.

Characterizing Substituted Imidazolidinetriones As A Novel Class Of Pyruvate Carboxylase Inhibitors, Nicholas O. Schneider

Dissertations (1934 -)

Pyruvate carboxylase (PC) is implicated in a variety of diseases, including type-2 diabetes, cancer, and bacterial/viral infections. However, there are currently no molecular tools capable of precisely manipulating PC activity both in vitro and in vivo. This dissertation describes the identification and characterization of 1,3-disubstituted imidazolidinetriones as a novel class of potent, selective, and permeable allosteric inhibitors of Staphylococcus aureus PC. Based on kinetic, structural, and biophysical data, this class of inhibitors is hypothesized to bind at the noncatalytic “exo binding” site on PC. This exo binding site is reportedly important for catalysis, but it had not previously been considered …

Fall 2024 Academic Calender, Registrar Office

Academic Calendars of the NSU Registrar

No abstract provided.