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Articles 306781 - 306810 of 5210768
Full-Text Articles in Entire DC Network
On The Turbulent Viscosity Parameter Cμ In The K–Ε Model, Harshit Mishra, Subhas Karan Venayagamoorthy
On The Turbulent Viscosity Parameter Cμ In The K–Ε Model, Harshit Mishra, Subhas Karan Venayagamoorthy
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
The Reynolds-averaged Navier–Stokes (RANS) models depend on empirical constants to close the Reynolds stress terms. The empirical constants were obtained using experiments conducted at low Reynolds numbers several decades ago. In this paper, we revisit the turbulent viscosity parameter Cμ, based on the stress–intensity ratio c2 = |uw|/k. Here, |uw| and k are the absolute values of the Reynolds stress and turbulent kinetic energy, respectively. Through a priori comparisons, we find that the currently accepted value of Cμ = 0.09 does not agree with the latest direct numerical simulation (DNS) and experimental datasets of wall-bounded turbulent planar flows. Therefore, …
Spectator 2024-10-10, Editors Of The Spectator
Remembering Vienna, Cardozo Law Institute In Holocaust And Human Rights (Clihhr), Jocelyn Getgen Kestenbaum
Remembering Vienna, Cardozo Law Institute In Holocaust And Human Rights (Clihhr), Jocelyn Getgen Kestenbaum
2024 Event Invitations
Join us for a special evening with Evelyn Konrad ’05, a Holocaust survivor and Cardozo alum, who will share her powerful story of resilience, survival and identity. Evelyn Konrad’s story was featured in the recently published book Austria and Us.
Racial Residential Segregation And Covid-19 Health Outcomes: Evidence From The State Of Georgia, Palak Patel, Simon Medcalfe, Catherine P. Slade
Racial Residential Segregation And Covid-19 Health Outcomes: Evidence From The State Of Georgia, Palak Patel, Simon Medcalfe, Catherine P. Slade
Journal of the Georgia Public Health Association
ABSTRACT
Background:
According to the Georgia Department of Public Health (GDPH), the state of Georgia reported 563,658 cumulative COVID-19 cases and 9,845 total deaths in 2020. Decades of research on racial disparities in health outcomes suggest we should not be surprised with the disproportionate number of cases, hospital visits, and deaths of non-white and Black Georgia residents. Racial disparities in health are often defined by a Social Determinants of Health (SDOH) model. One understudied SDOH is racial residential segregation. In this study we explore the relationship between racial residential segregation and COVID-19 health outcomes. Our paper addresses critical challenges for …
An Epiq Mass Shelter Training For Public Health Nurses In Georgia To Improve Core Competencies In Disaster Preparedness: A Pilot Study, Ashlie L. Pullen, Sonya Shinhoster
An Epiq Mass Shelter Training For Public Health Nurses In Georgia To Improve Core Competencies In Disaster Preparedness: A Pilot Study, Ashlie L. Pullen, Sonya Shinhoster
Journal of the Georgia Public Health Association
Background: Research shows that nurses are often ill-prepared for disaster response. A survey conducted by the Georgia Department of Public Health Office of Nursing in April of 2021, demonstrated that 45% of the public health nurses surveyed had never deployed to a mass congregate shelter, and 43% reported they had no formal training related to emergency preparedness or mass sheltering. The purpose of this pilot study was to measure public health nurses’ improvement in familiarity with emergency preparedness and disaster response core competencies as defined by the Emergency Preparedness Information Questionnaire (EPIQ) after a focused educational program and tabletop workshop. …
Understanding The Role Of Perceived Racial Discrimination On Adolescent Mental Health During The Covid-19 Pandemic, Jill V. Klosky, Delia Lang, Briana Woods-Jaeger, Julie Gazmararian
Understanding The Role Of Perceived Racial Discrimination On Adolescent Mental Health During The Covid-19 Pandemic, Jill V. Klosky, Delia Lang, Briana Woods-Jaeger, Julie Gazmararian
Journal of the Georgia Public Health Association
Abstract
Background: Adolescent mental health declined during the COVID-19 pandemic. Racial discrimination, which may negatively affect adolescent mental health, has increased. This study sought to understand whether pre-pandemic reports of racial discrimination predicted changes in adolescent depression, anxiety, and self-esteem from before to during the COVID-19 pandemic.
Methods: Two online surveys were administered at two public high schools in semi-rural, north-central Georgia; one in Spring 2020, just before the closing of public schools due to COVID-19; the other to the same students in Fall 2020.
Results: Most participants were White (62%) and the majority (88%), reported the same or better …
93rd Annual Georgia Public Health Association Meeting And Conference Report, Jimmie H. Smith Jr, Angela Peden, Patrina L. Bowles
93rd Annual Georgia Public Health Association Meeting And Conference Report, Jimmie H. Smith Jr, Angela Peden, Patrina L. Bowles
Journal of the Georgia Public Health Association
The 93rd Annual Meeting and Conference of the Georgia Public Health Association (GPHA) was held in Jekyll Island, Georgia, at the Jekyll Island Convention Center, on May 3-5, 2023. The goal of the 2023 Georgia Public Health Association Annual Meeting and Conference was to assemble emerging public health professionals, current practitioners, academicians, governing entities, and community stakeholders for educational opportunities and networking to support the vision and mission of GPHA.
The theme for the 2023 Georgia Public Health Association Annual Meeting and Conference theme was selected by the GPHA Executive Board during a meeting in the early fall of …
Planting The Seed: Using Research As A Tool To Revitalize Puberty Ceremonies In Anishinaabe Communities, Miigis B. Gonzalez, Alexandra Ziibiins Johnson, Lisa Awan Martin, Jillian Naawakwe, Jillian Fish, Lalaine Sevillano, Melissa L. Walls, Lee Obizaan Staples
Planting The Seed: Using Research As A Tool To Revitalize Puberty Ceremonies In Anishinaabe Communities, Miigis B. Gonzalez, Alexandra Ziibiins Johnson, Lisa Awan Martin, Jillian Naawakwe, Jillian Fish, Lalaine Sevillano, Melissa L. Walls, Lee Obizaan Staples
School of Social Work Faculty Publications and Presentations
Purpose: The purpose of this work is to honor the wisdoms of Anishinaabe Elders, community and culture by interweaving these teachings with my own (first author) Anishinaabe experiences and a research project. Ceremonies are an important health practice for Anishinaabe people. This project aimed to gain a clearer conceptualization of the protective role of Anishinaabe puberty ceremonies on health in adolescence and across the lifespan. Design/methodology/approach Spiritual offerings guided this project at every stage including inviting Elders and community members into shared spaces of storytelling and teaching elicitation and grounding me as I carefully adopted the use of a western …
Extra Añejo, October 10, 2024 [Program], University Of Northern Iowa. School Of Music.
Extra Añejo, October 10, 2024 [Program], University Of Northern Iowa. School Of Music.
Music Recital Programs
Program of a music recital given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.
Systematic Review On Self-Control A Predictor Of Work Performance Of Librarians In Public Universities In South Western Nigeria., Tola Abosede Ogunojemite
Systematic Review On Self-Control A Predictor Of Work Performance Of Librarians In Public Universities In South Western Nigeria., Tola Abosede Ogunojemite
Library Philosophy and Practice (e-journal)
The purpose of, this study is to examine how self-control predicts work performance of librarians in public universities in southwestern Nigeria.
The research design adopted for the study was descriptive research survey design of the correlational type. A multi-stage sampling technique was adopted to draw 229 respondents. Data analysis was conducted based on frequency, percentage, mean and standard deviation, to answer the research questions Respondents of this study consisted of males (43.9%) and females (56.1%), majority (28.7%) aged 26-30. The findings revealed that the level of self-control of librarians in public universities in south-western Nigeria was high following the norm …
A Conversation With Sam And Libby Edelman: Legends In The Footwear Industry, Cardozo Fame Center, Cardozo Fashion Law Society
A Conversation With Sam And Libby Edelman: Legends In The Footwear Industry, Cardozo Fame Center, Cardozo Fashion Law Society
2024 Event Invitations
Join Cardozo's FAME Center and the Fashion Law Society as they present fashion industry icons, Sam and Libby Edelman in conversation with FAME Director and Cardozo Professor, Barbara Kolsun. Reception to follow.
Lowering The Burden: Shorter Versions Of The Program Sustainability Assessment Tool (Psat) And Clinical Sustainability Assessment Tool (Csat), Sara Malone, Kim Prewitt, Virginia Mckay, Luke Zabotka, Caren Bacon, Douglas A Luke
Lowering The Burden: Shorter Versions Of The Program Sustainability Assessment Tool (Psat) And Clinical Sustainability Assessment Tool (Csat), Sara Malone, Kim Prewitt, Virginia Mckay, Luke Zabotka, Caren Bacon, Douglas A Luke
2020-Current year OA Pubs
BACKGROUND: Although significant advances have been made in the conceptualization of sustainability, having pragmatic, psychometrically valid tools remains a need within the field. Our previous work has developed frameworks and tools to assess both program sustainability and clinical sustainability capacity. This work presents new, psychometrically tested short versions of the Program Sustainability Assessment Tool (PSAT) and the Clinical Sustainability Assessment Tool (CSAT).
METHODS: These methods were conducted in identical, parallel processes for the CSAT and PSAT. Previously collected data for these instruments was obtained across a variety of settings, contexts, and participants. We first conducted testing to determine cronbach's alpha …
Literature Review Of Maritime Cyber Security: The First Decade, Avanthika Vineetha Harish, Kimberly Tam, Kevin Jones
Literature Review Of Maritime Cyber Security: The First Decade, Avanthika Vineetha Harish, Kimberly Tam, Kevin Jones
School of Engineering, Computing and Mathematics
This is a comprehensive review of the current body of work for cyber security in the marine and maritime sectors. Reviews are useful as a field develops, both for those new to the field, and those contributing to a section of the existing body of work. This looks at the phases of research, from exploratory and positional papers in the early 2010s, to the more recent experimental research, and how ``maritime cyber security" has branched into subtopics addressing human factors, policy, law, cyber-physical security, and more. In addition to different topics of research, this comprehensive review summaries the focus of …
October 10, 2024, James Madison University
October 10, 2024, James Madison University
The Breeze, 2020-
The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.
October 10, 2024, The Daily Mississippian
October 10, 2024, The Daily Mississippian
Daily Mississippian (all digitized issues)
No abstract provided.
The Tarascan Project (1939-1947) Researchers From Unm In A Collaborative Anthropological Research Between Mexico And The Us, Dr. Lorena Ojeda Dávila, Latin American And Iberian Institute
The Tarascan Project (1939-1947) Researchers From Unm In A Collaborative Anthropological Research Between Mexico And The Us, Dr. Lorena Ojeda Dávila, Latin American And Iberian Institute
LAII Events
Thursday, October 10, 2024 | 02:00 pm
Zoom
801 Yale Blvd NE (campus building #165)
About:
Join LAII for a talk about UNM’s involvement in the Tarascan Project.
The Tarascan Project was a political collaboration between academic institutions and Mexican and American government agencies. The goal of the project was to carry out anthropological research activities in the indigenous regions of Michoacán. Its official duration was from 1939 to 1947, but its influence persisted for decades. The main institutions that financially and academically supported the project in Mexico were the National Polytechnic Institute, the National Institute of Anthropology and History, …
Diverse Disconnectedness: Homophily, Social Capital Inequality, And Student Experiences In Law School, Anthony Paik, Swethaa Ballakrishnen, Carole Silver, Steven Boutcher, Tanya Rouleau Whitworth
Diverse Disconnectedness: Homophily, Social Capital Inequality, And Student Experiences In Law School, Anthony Paik, Swethaa Ballakrishnen, Carole Silver, Steven Boutcher, Tanya Rouleau Whitworth
Faculty Publications
Law school students are encouraged frequently to “network.” However, depending on demographic categories, they may have access to differently resourced social networks in law school. In this article, we draw from our mixed-methods research to explore this diversity of experience, its limitations of access, and the possible network inequalities that may limit the value of legal education to diverse students across different institutional contexts. Using survey and network data (N = 744), collected during the fall of 2019 from three law schools, as well as supplementary interview data (N = 55), we examined students’ social networks, the structures of these …
Impact Of Age On Pharmacogenomics And Treatment Outcomes Of B-Cell Acute Lymphoblastic Leukemia, Satoshi Yoshimura, Zhenhua Li, Yoshihiro Gocho, Wenjian Yang, Kristine R Crews, Kathryn G Roberts, Mary V Relling, Jiyang Yu, Allen E J Yeoh, Mignon L Loh, Caner Saygin, Mark R Litzow, Sima Jeha, Seth E Karol, Hiroto Inaba, Ching-Hon Pui, Marina Konopleva, Nitin Jain, Wendy Stock, Elisabeth Paietta, Elias Jabbour, Steven M Kornblau, William E Evans, Jun J Yang
Impact Of Age On Pharmacogenomics And Treatment Outcomes Of B-Cell Acute Lymphoblastic Leukemia, Satoshi Yoshimura, Zhenhua Li, Yoshihiro Gocho, Wenjian Yang, Kristine R Crews, Kathryn G Roberts, Mary V Relling, Jiyang Yu, Allen E J Yeoh, Mignon L Loh, Caner Saygin, Mark R Litzow, Sima Jeha, Seth E Karol, Hiroto Inaba, Ching-Hon Pui, Marina Konopleva, Nitin Jain, Wendy Stock, Elisabeth Paietta, Elias Jabbour, Steven M Kornblau, William E Evans, Jun J Yang
Faculty, Staff and Student Publications
Purpose: Acute lymphoblastic leukemia (ALL) can occur across all age groups, with a strikingly higher cure rate in children compared with adults. However, the pharmacological basis of age-related differences in ALL treatment response remains unclear.
Methods: Studying 767 children and 309 adults with newly diagnosed B-cell ALL enrolled on frontline trials at St Jude Children's Research Hospital, MD Anderson Cancer Center, the Alliance for Clinical Trials in Oncology, and the ECOG-ACRIN Cancer Research Group, we determined the ex vivo sensitivity of leukemia cells to 21 drugs. Twenty-three ALL molecular subtypes were identified using RNA sequencing. We systematically characterized the associations …
Assessing Water Clarity Status And Long-Term Trends In North America's Largest Lakes Using Esa's Ocean Colour Climate Change Initiative (Oc-Cci) Products, Caren Binding, Matt Morison, Michael Sayers, Karl Bosse, Xinhua Zhu, Chuiqing Zeng, Varunan Theenathayalan
Assessing Water Clarity Status And Long-Term Trends In North America's Largest Lakes Using Esa's Ocean Colour Climate Change Initiative (Oc-Cci) Products, Caren Binding, Matt Morison, Michael Sayers, Karl Bosse, Xinhua Zhu, Chuiqing Zeng, Varunan Theenathayalan
Michigan Tech Publications
Water clarity, as measured by Secchi disk depth (ZSD) or diffuse attenuation (Kd), is an important indicator of a lake's ecosystem state and can be reliably retrieved using satellite remote sensing. By combining data from multiple satellite missions, the European Space Agency's Ocean Colour Climate Change Initiative (OC-CCI) aims to deliver stable, long-term, satellite data products suitable for trend assessments. Here we demonstrate the value of OC-CCI products for reporting on water clarity status and long-term trends in North America's largest lakes. Extensive matchups between the OC-CCI Kd at 490 nm (Kd490) and in situ ZSD observations spanning 25 years …
Dubai Urban Planning 2040: Resource Requirements In The Urban District 5, Bakhit Alfalasi
Dubai Urban Planning 2040: Resource Requirements In The Urban District 5, Bakhit Alfalasi
Theses
The availability of water, food, energy and air quality resources is compromised by prevailing global issues like environmental stress, climate change, and population growth. This research study details the different requirements for Dubai urban District 5 based on the tenets laid out in the Urban Planning 2040 initiative. The literature review section looks into existing literature on the present state of affairs in the UAE as regards availability of water, food, and energy resources in the country and implications of their production processes on air quality. The Study will employ an exploratory research design, where a systematic review of literature …
Churning The Tides Of Care: When Nurse Turnover Makes Waves In Patient Access To Primary Care, Trang N D Pham, Laura A Petersen, Lechauncy Woodard, Richard Sorelle, Cheng Rebecca Jiang, Frederick L Oswald, Daniel R Murphy, Hilary N Touchett, Joshua Hamer, Sylvia J Hysong
Churning The Tides Of Care: When Nurse Turnover Makes Waves In Patient Access To Primary Care, Trang N D Pham, Laura A Petersen, Lechauncy Woodard, Richard Sorelle, Cheng Rebecca Jiang, Frederick L Oswald, Daniel R Murphy, Hilary N Touchett, Joshua Hamer, Sylvia J Hysong
Faculty, Staff and Students Publications
BACKGROUND: Team-based primary care (PC) enhances the quality of and access to health care. The Veterans Health Administration (VHA) implements team-based care through Patient Aligned Care Teams (PACTs), consisting of four core members: a primary care provider, registered nurse (RN) care manager, licensed vocational nurse, and scheduling clerk. RNs play a central role: they coordinate patient care, manage operational needs, and serve as a patient point of contact. Currently, it is not known how varying levels of RN staffing on primary care teams impact patient outcomes.
OBJECTIVE: This study aims to empirically assess how the stability of RN staffing within …
Larp1 Haploinsufficiency Is Associated With An Autosomal Dominant Neurodevelopmental Disorder, Robert Best, Kevin Chen, Josephine Morris, Zinaida Dedeic, Anna Childers, R Curtis Rogers, Barbara R Dupont, Cindy Skinner, Sébastien Küry, Kevin Uguen, Marc Planes, Danielle Monteil, Megan Li, Aviva Eliyahu, Lior Greenbaum, Nofar Mor, Thomas Besnard, Bertrand Isidor, Benjamin Cogné, Alyssa Blesson, Anne Comi, Ingrid M Wentzensen, Blake Vuocolo, Seema R Lalani, Roberta Sierra, Lori Berry, Kent Carter, Stephan J Sanders, Sarah P Blagden
Larp1 Haploinsufficiency Is Associated With An Autosomal Dominant Neurodevelopmental Disorder, Robert Best, Kevin Chen, Josephine Morris, Zinaida Dedeic, Anna Childers, R Curtis Rogers, Barbara R Dupont, Cindy Skinner, Sébastien Küry, Kevin Uguen, Marc Planes, Danielle Monteil, Megan Li, Aviva Eliyahu, Lior Greenbaum, Nofar Mor, Thomas Besnard, Bertrand Isidor, Benjamin Cogné, Alyssa Blesson, Anne Comi, Ingrid M Wentzensen, Blake Vuocolo, Seema R Lalani, Roberta Sierra, Lori Berry, Kent Carter, Stephan J Sanders, Sarah P Blagden
Faculty, Staff and Students Publications
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects approximately 4% of males and 1% of females in the United States. While causes of ASD are multi-factorial, single rare genetic variants contribute to around 20% of cases. Here, we report a case series of seven unrelated probands (6 males, 1 female) with ASD or another variable NDD phenotype attributed to de novo heterozygous loss of function or missense variants in the gene LARP1 (La ribonucleoprotein 1). LARP1 encodes an RNA-binding protein that post-transcriptionally regulates the stability and translation of thousands of mRNAs, including those regulating cellular metabolism and …
Rapid Evolution Of Mitochondrion-Related Genes In Haplodiploid Arthropods, Robert M Waterhouse, Xin Zhou, Michael E Pfrender
Rapid Evolution Of Mitochondrion-Related Genes In Haplodiploid Arthropods, Robert M Waterhouse, Xin Zhou, Michael E Pfrender
Faculty, Staff and Students Publications
Background: Mitochondrial genes and nuclear genes cooperate closely to maintain the functions of mitochondria, especially in the oxidative phosphorylation (OXPHOS) pathway. However, mitochondrial genes among arthropod lineages have dramatic evolutionary rate differences. Haplodiploid arthropods often show fast-evolving mitochondrial genes. One hypothesis predicts that the small effective population size of haplodiploid species could enhance the effect of genetic drift leading to higher substitution rates in mitochondrial and nuclear genes. Alternatively, positive selection or compensatory changes in nuclear OXPHOS genes could lead to the fast-evolving mitochondrial genes. However, due to the limited number of arthropod genomes, the rates of evolution for nuclear …
Clinical And Functional Studies Of Mtor Variants In Smith-Kingsmore Syndrome Reveal Deficits Of Circadian Rhythm And Sleep-Wake Behavior, Andrew C Liu, Yang Shen, Carolyn R Serbinski, Hongzhi He, Destino Roman, Mehari Endale, Lindsey Aschbacher-Smith, Katherine A King, Jorge L Granadillo, Isabel López, Darcy A Krueger, Thomas J Dye, David F Smith, John B Hogenesch, Carlos E Prada
Clinical And Functional Studies Of Mtor Variants In Smith-Kingsmore Syndrome Reveal Deficits Of Circadian Rhythm And Sleep-Wake Behavior, Andrew C Liu, Yang Shen, Carolyn R Serbinski, Hongzhi He, Destino Roman, Mehari Endale, Lindsey Aschbacher-Smith, Katherine A King, Jorge L Granadillo, Isabel López, Darcy A Krueger, Thomas J Dye, David F Smith, John B Hogenesch, Carlos E Prada
2020-Current year OA Pubs
Heterozygous de novo or inherited gain-of-function mutations in the MTOR gene cause Smith-Kingsmore syndrome (SKS). SKS is a rare autosomal dominant condition, and individuals with SKS display macrocephaly/megalencephaly, developmental delay, intellectual disability, and seizures. A few dozen individuals are reported in the literature. Here, we report a cohort of 28 individuals with SKS that represent nine MTOR pathogenic variants. We conducted a detailed natural history study and found pathophysiological deficits among individuals with SKS in addition to the common neurodevelopmental symptoms. These symptoms include sleep-wake disturbance, hyperphagia, and hyperactivity, indicative of homeostatic imbalance. To characterize these variants, we developed cell …
Recent Progress In Modeling And Treating Diabetes Using Stem Cell-Derived Islets, Marlie M Maestas, Maggie H Bui, Jeffrey R Millman
Recent Progress In Modeling And Treating Diabetes Using Stem Cell-Derived Islets, Marlie M Maestas, Maggie H Bui, Jeffrey R Millman
2020-Current year OA Pubs
Stem cell-derived islets (SC-islets) offer the potential to be an unlimited source of cells for disease modeling and the treatment of diabetes. SC-islets can be genetically modified, treated with chemical compounds, or differentiated from patient derived stem cells to model diabetes. These models provide insights into disease pathogenesis and vulnerabilities that may be targeted to provide treatment. SC-islets themselves are also being investigated as a cell therapy for diabetes. However, the transplantation process is imperfect; side effects from immunosuppressant use have reduced SC-islet therapeutic potential. Alternative methods to this include encapsulation, use of immunomodulating molecules, and genetic modification of SC-islets. …
Rethinking Our Future: Describing And Enhancing The Impacts Of Dissemination And Implementation Science For Cancer Prevention And Control, Vianca C. Soulette, Karen M. Emmons, Douglas A. Luke, Peg Allen, Bobbi J. Carothers, Ross C. Brownson
Rethinking Our Future: Describing And Enhancing The Impacts Of Dissemination And Implementation Science For Cancer Prevention And Control, Vianca C. Soulette, Karen M. Emmons, Douglas A. Luke, Peg Allen, Bobbi J. Carothers, Ross C. Brownson
2020-Current year OA Pubs
No abstract provided.
Aligning The World Health Organization's (Who) Package Of Interventions For Rehabilitation For Cancer With The Mission Of The International Psycho-Oncology Society's: Promoting Psychosocial Care For All People Affected By Cancer, Christina Signorelli, Nicolas H. Hart, Louise Mullen, Larissa Nekhlyudov, Luzia Travado, Wendy W.T. Lam, Melissa Henry, Csaba László Dégi, Darren Haywood, Michael Jefford
Aligning The World Health Organization's (Who) Package Of Interventions For Rehabilitation For Cancer With The Mission Of The International Psycho-Oncology Society's: Promoting Psychosocial Care For All People Affected By Cancer, Christina Signorelli, Nicolas H. Hart, Louise Mullen, Larissa Nekhlyudov, Luzia Travado, Wendy W.T. Lam, Melissa Henry, Csaba László Dégi, Darren Haywood, Michael Jefford
Research outputs 2022 to 2026
The number of people living with and beyond cancer continues to increase worldwide, bringing significant attention to their rehabilitation needs. Globally, psychosocial services are largely inadequate, with many cancer survivors experiencing unmet psychosocial needs. The World Health Organization (WHO) recognizes rehabilitation as an essential component of universal health coverage to prevent disease-related conditions, while also improving physical and mental functioning and overall well-being. The Package of Interventions for Rehabilitation (PIR) was developed by the WHO to address the global need for rehabilitation across 20 conditions with high prevalence and high levels of associated disability, including cancer. Many aspects of the …
Long Term Impact Of Covid 19 On Psychiatric Health And Quality Of Life In Recovered Patients, Preetika Baghel, Pradeep Kumar P C, Kishor M
Long Term Impact Of Covid 19 On Psychiatric Health And Quality Of Life In Recovered Patients, Preetika Baghel, Pradeep Kumar P C, Kishor M
International Journal of Health and Allied Sciences
Background: Covid-19 has a devastating impact on different dimensions of life, including health. Recent studies have highlighted the effects of prolonged Covid-19 symptoms on mental health.
Aim: This study aims to 1) assess psychiatric illness among individuals previously diagnosed with COVID-19 infection and treated on an inpatient basis, and 2) evaluate the quality of life of individuals with and without psychiatric illness.
Method: This hospital-based cross-sectional study was conducted at a tertiary care general hospital in South India and involved 200 patients with COVID-19 infection who received treatment through an inpatient facility. The study utilized a sociodemographic …
Exploring High-Penetrance Genes In Breast Cancer Associated Genetic Syndromes: Insights Into Genetic Predisposition And Clinical Implications, Nadha Abdul Razack, Samudyata C. Prabhuswamimath
Exploring High-Penetrance Genes In Breast Cancer Associated Genetic Syndromes: Insights Into Genetic Predisposition And Clinical Implications, Nadha Abdul Razack, Samudyata C. Prabhuswamimath
International Journal of Health and Allied Sciences
Breast cancer, the most common cancer in women globally, has a genetic predisposition in 5-10% of cases. This paper examines high-penetrant genes TP53, PTEN, CDH1, and STK11, which are associated with hereditary syndromes such as Peutz-Jeghers, Hereditary Diffuse Gastric Cancer, Cowden, and Li-Fraumeni. Mutations in these high penetrant genes significantly increases breast cancer risk, resulting in subtypes characterized by higher nuclear grading, increased invasiveness, and greater metastasis potential. Understanding the molecular mechanisms and interactions of these genes with various breast cancer subtypes is essential for improving risk assessment, early detection, and the development of personalized treatment strategies.
Sestrin 2 As A New Biomarker In Obesity And Diabetes Mellitus: A New Key Player In The Metabolic Regulation, Shashank M Patil, Jayanthi M K, Ramith Ramu
Sestrin 2 As A New Biomarker In Obesity And Diabetes Mellitus: A New Key Player In The Metabolic Regulation, Shashank M Patil, Jayanthi M K, Ramith Ramu
International Journal of Health and Allied Sciences
The global health crisis of diabetes linked to obesity necessitates innovative biomarkers for early diagnosis and targeted treatment. This study explores the pivotal role of sestrins, evolutionarily conserved proteins, in the intricate interplay between obesity and diabetes. Highlighting their significance as regulators of metabolic balance, stress response, and cellular homeostasis, particularly sestrin 2 (SESN2), the study delves into their impact on oxidative stress, insulin sensitivity, and inflammatory responses. Recent studies have highlighted the dysregulation of sestrins in obesity and diabetes mellitus, suggesting their potential as diagnostic markers and therapeutic targets. Examining the molecular processes involving AMP-activated protein kinase (AMPK) and …