Digital Commons Network^™

Influenza C Virus In Us Children With Acute Respiratory Infection 2016–2019, Bethany K Sederdahl, Geoffrey A Weinberg, Angela P Campbell, Rangaraj Selvarangan, Jennifer E Schuster, Joana Y Lively, Samantha M Olson, Julie A Boom, Pedro A Piedra, Natasha B Halasa, Laura Stewart, Peter G Szilagyi, G K Balasubramani, Theresa Sax, Judith M Martin, Robert W Hickey, Marian G Michaels, John V Williams, New Vaccine Surveillance Network

Faculty, Staff and Students Publications

Influenza C virus (ICV) is an orthomyxovirus related to influenza A and B, yet due to few commercial assays, epidemiologic studies may underestimate incidence of ICV infection and disease. We describe the epidemiology and characteristics of ICV within the New Vaccine Surveillance Network (NVSN), a Centers for Disease Control and Prevention (CDC)-led network that conducts population-based surveillance for pediatric acute respiratory illness (ARI). Nasal or/combined throat swabs were collected from emergency department (ED) or inpatient ARI cases, or healthy controls, between 12/05/2016-10/31/2019 and tested by molecular assays for ICV and other respiratory viruses. Parent surveys and chart review were used …

Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022, Alpha Oumar Diallo, Mary E Wikswo, Iddrisu Sulemana, Leila C Sahni, Julie A Boom, Sasirekha Ramani, Rangaraj Selvarangan, Mary E Moffatt, Christopher J Harrison, Natasha Halasa, James Chappell, Laura Stewart, Mary Allen Staat, Elizabeth Schlaudecker, Christina Quigley, Eileen J Klein, Janet A Englund, Danielle M Zerr, Geoffrey A Weinberg, Peter G Szilagyi, Christina Albertin, Samantha H Johnston, John V Williams, Marian G Michaels, Robert W Hickey, Aaron T Curns, Michelle Honeywood, Slavica Mijatovic-Rustempasic, Mathew D Esona, Michael D Bowen, Umesh D Parashar, Rashi Gautam, Sara A Mirza, Jacqueline E Tate

Faculty, Staff and Students Publications

Background: Rotavirus was the leading cause of acute gastroenteritis among US children until vaccine introduction in 2006, after which, substantial declines in severe rotavirus disease occurred. We evaluated rotavirus vaccine effectiveness (VE) over 13 years (2009-2022).

Methods: We analyzed data from the New Vaccine Surveillance Network using a test-negative case-control design to estimate rotavirus VE against laboratory-confirmed rotavirus infections among children seeking care for acute gastroenteritis (≥3 diarrhea or ≥1 vomiting episodes within 24 hours) in the emergency department (ED) or hospital. Case-patients and control-patients were children whose stool specimens tested rotavirus positive or negative, respectively, by enzyme immunoassay or …

Linkage Between Fuz And Gpr161 Genes Regulates Sonic Hedgehog Signaling During Mouse Neural Tube Development, Sung-Eun Kim, Hyun-Yi Kim, Bogdan J Wlodarczyk, Richard H Finnell

Faculty, Staff and Students Publications

Sonic hedgehog (Shh) signaling regulates embryonic morphogenesis utilizing the primary cilium, the cell's antenna, which acts as a signaling hub. Fuz, an effector of planar cell polarity signaling, regulates Shh signaling by facilitating cilia formation, and the G protein-coupled receptor 161 (Gpr161) is a negative regulator of Shh signaling. The range of phenotypic malformations observed in mice bearing mutations in either of the genes encoding these proteins is similar; however, their functional relationship has not been previously explored. This study identified the genetic and biochemical linkage between Fuz and Gpr161 in mouse neural tube development. Fuz was found to be …

The Undiagnosed Diseases Network: Characteristics Of Solvable Applicants And Diagnostic Suggestions For Nonaccepted Ones, John J Mulvihill, Laura Findley, Weihong Ni, Janet S Sinsheimer, F Session Cole, Cecilia Esteves, Jonathan A Bernstein, John H Newman, Matthew T Wheeler, Jill R Mokry, Undiagnosed Diseases Network

Faculty, Staff and Students Publications

Purpose: Can certain characteristics identify as solvable some undiagnosed patients who seek extensive evaluation and thorough record review, such as by the Undiagnosed Diseases Network (UDN)?

Methods: The UDN is a national research resource to solve medical mysteries through team science. Applicants provide informed consent to access to their medical records. After review, expert panels assess if applicants meet inclusion and exclusion criteria to select participants. When not accepting applicants, UDN experts may offer suggestions for diagnostic efforts. Using minimal information from initial applications, we compare features in applicants who are not accepted with those who are accepted and either …

Stareg: Statistical Replicability Analysis Of High Throughput Experiments With Applications To Spatial Transcriptomic Studies, Yan Li, Xiang Zhou, Rui Chen, Xianyang Zhang, Hongyuan Cao

Faculty, Staff and Students Publications

Replicable signals from different yet conceptually related studies provide stronger scientific evidence and more powerful inference. We introduce STAREG, a statistical method for replicability analysis of high throughput experiments, and apply it to analyze spatial transcriptomic studies. STAREG uses summary statistics from multiple studies of high throughput experiments and models the the joint distribution of p-values accounting for the heterogeneity of different studies. It effectively controls the false discovery rate (FDR) and has higher power by information borrowing. Moreover, it provides different rankings of important genes. With the EM algorithm in combination with pool-adjacent-violator-algorithm (PAVA), STAREG is scalable to datasets …

Unraveling The Link: Seizure Characteristics And Ammonia Levels In Urea Cycle Disorder During Hyperammonemic Crises, Mongkol Chanvanichtrakool, John M Schreiber, Wei-Liang Chen, John Barber, Anqing Zhang, Nicholas Ah Mew, Andreas Schulze, Greta Wilkening, Sandesh C S Nagamani, Andrea Gropman, Urea Cycle Disease Consortium

Faculty, Staff and Students Publications

Background: This retrospective clinical study performed at a single clinical center aimed to identify the prevalence of seizures in individuals with urea cycle disorders (UCDs) with and without hyperammonemic (HA) crises. In addition, we sought to correlate the utility of biochemical markers and electroencephalography (EEG) in detecting subclinical seizures during HA.

Methods: Medical records of individuals with UCDs enrolled in Urea Cycle Disorders Consortium Longitudinal Study (UCDC-LS) (NCT00237315) at Children's National Hospital between 2006 and 2022 were reviewed for evidence of clinical and subclinical seizuress during HA crises, and initial biochemical levels concurrently.

Results: Eighty-five individuals with UCD …

Inhaled Corticosteroids Attenuate The Association Of Fine Particulate Matter And Acute Asthma Events, Kristen A Staggers, Paula Sierra, Drew A Helmer, Charles Minard, Meredith C Mccormack, Tianshi David Wu

Faculty, Staff and Students Publications

No abstract provided.

Evaluating Progress And Accountability For Achieving Cop26 Health Programme International Ambitions For Sustainable, Low-Carbon, Resilient Health-Care Systems, Iris Martine Blom, Fawzia N Rasheed, Hardeep Singh, Matthew J Eckelman, Meghnath Dhimal, Martin Hensher, Renzo R Guinto, Alice Mcgushin, Xuejuan Ning, Poornima Prabhakaran, Marina Romanello, Dana Van Alphen, Nick Watts, Jessica C Yu, Carol Zavaleta-Cortijo, Andrea J Macneill, Jodi D Sherman

Faculty, Staff and Students Publications

A global initiative to develop low-carbon, resilient health systems-the COP26 Health Programme-launched at the UN Framework Convention on Climate Change 26th Conference of the Parties (COP26) in 2021. As of May, 2024, 83 nations have committed to participate in this initiative. This analysis evaluates the effectiveness of existing and proposed indicators towards public monitoring and accountability to these commitments. Our findings reveal substantial gaps in data availability and indicator relevance, with many countries reporting process indicators that do not reflect actual progress towards achieving sustainable health-care systems. We found a dearth of suitable indicators and an urgent need to develop …

Psychometric Evaluation Of Clinician- And Caregiver-Reported Clinical Severity Assessments For Individuals With Cdkl5 Deficiency Disorder, Jacinta M Saldaris, Peter Jacoby, Jenny Downs, Eric D Marsh, Helen Leonard, Elia Pestana-Knight, Rajsekar Rajaraman, Judith Weisenberg, Bernhard Suter, Heather E Olson, Dana Price, William Hong, Erin Prange, Tim A Benke, Scott Demarest

Faculty, Staff and Students Publications

Objective: The CDKL5 Clinical Severity Assessment (CCSA) is a comprehensive, content-validated measurement tool capturing the diverse challenges of cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD), a genetically caused developmental epileptic encephalopathy (DEE). The CCSA is divided into clinician-reported (CCSA-Clinician) and caregiver-reported (CCSA-Caregiver) assessments. The aim of this study was to evaluate the factor structure of these measures through confirmatory factor analysis (CFA) and evaluate their validity and reliability.

Methods: Participants were recruited from the International CDKL5 Clinical Research Network to take part in an in-clinic CCSA-Clinician evaluation (n = 148) and/or complete the CCSA-Caregiver questionnaire (n = 198). CFA was …

Correspondence Re Essam El-Sayed Felaya Et Al, Kiyeun Nam, Dongho Lee, Seokjoon Hwang, Minsu Seo, Taeheon Lee, Yonghoon Lee, Michael Y Lee

Faculty, Staff and Students Publications

No abstract provided.

Intimate Partner Violence-Related Brain Injury: Unmasking And Addressing The Gaps, Carrie Esopenko, Divya Jain, Shambhu Prasad Adhikari, Kristen Dams-O'Connor, Michael Ellis, Halina Lin Haag, Elizabeth S Hovenden, Finian Keleher, Inga K Koerte, Hannah M Lindsey, Amy D Marshall, Karen Mason, J Scott Mcnally, Deleene S Menefee, Tricia L Merkley, Emma N Read, Philine Rojcyk, Sandy R Shultz, Mujun Sun, Danielle Toccalino, Eve M Valera, Paul Van Donkelaar, Cheryl Wellington, Elisabeth A Wilde

Faculty, Staff and Students Publications

Intimate partner violence (IPV) is a significant, global public health concern. Women, individuals with historically underrepresented identities, and disabilities are at high risk for IPV and tend to experience severe injuries. There has been growing concern about the risk of exposure to IPV-related head trauma, resulting in IPV-related brain injury (IPV-BI), and its health consequences. Past work suggests that a significant proportion of women exposed to IPV experience IPV-BI, likely representing a distinct phenotype compared with BI of other etiologies. An IPV-BI often co-occurs with psychological trauma and mental health complaints, leading to unique issues related to identifying, prognosticating, and …

Publisher Correction: Detection Of Mosaic And Population-Level Structural Variants With Sniffles2, Moritz Smolka, Luis F Paulin, Christopher M Grochowski, Dominic W Horner, Medhat Mahmoud, Sairam Behera, Ester Kalef-Ezra, Mira Gandhi, Karl Hong, Davut Pehlivan, Sonja W Scholz, Claudia M B Carvalho, Christos Proukakis, Fritz J Sedlazeck

Faculty, Staff and Students Publications

This corrects the article "Detection of mosaic and population-level structural variants with Sniffles2" on page 1571.

A Coupled Spatial-Network Model: A Mathematical Framework For Applications In Epidemiology, Hannah Kravitz, Christina Duron, Moysey Brio

Mathematics and Statistics Faculty Publications and Presentations

There is extensive evidence that network structure (e.g., air transport, rivers, or roads) may significantly enhance the spread of epidemics into the surrounding geographical area. A new compartmental modeling framework is proposed which couples well-mixed (ODE in time) population centers at the vertices, 1D travel routes on the graph’s edges, and a 2D continuum containing the rest of the population to simulate how an infection spreads through a population. The edge equations are coupled to the vertex ODEs through junction conditions, while the domain equations are coupled to the edges through boundary conditions. A numerical method based on spatial finite …

The Use Of Developmental Program Evaluation For State Continued Approval In Educator Preparation, Suzanne L. Roberts

USF Tampa Graduate Theses and Dissertations

Working as a teacher educator today means working under an ever-present regulatory gaze. Accountability mechanisms, including state program approval processes, have been layered resulting in complexity. External assessments have failed to provide the data needed to support continuous improvement. There have been calls for combining external and internal evaluation processes to better drive continuous improvement. Developmental Program Evaluation (DPE) is an approach that claims to support program development in the middle space between top-down and bottom-up forces. This study examines the use of DPE in the middle space between mandated state approval processes and a small educator preparation program’s effort …

Exploring The Relationship Between Intrinsic Motivation And Receptivity To Mhealth Interventions, Varun Mishra, Sarah Hong, David Kotz

Dartmouth Scholarship

Just-in-Time Adaptive Interventions aim to deliver the right type and amount of support at the right time. This involves determining a user's state of receptivity - the degree to which a user is willing to accept, process, and use the intervention. Although past work has found that users are more receptive to notifications they view as useful, there is no existing research on whether users' intrinsic motivation for the underlying topic of mHealth interventions affects their receptivity. To explore this, we conducted a study with 20 participants over three weeks, where participants interacted with a chatbot-based digital coach to receive …

Sound, Gentrification, And Ephethereal Justice, Allie Martin

Dartmouth Scholarship

Gentrification transforms neighborhoods and erodes intimacies, creating spaces of displacement and exclusivity. Where, then, is justice in a gentrifying city? In this article, I argue that sound offers an opening into a fleeting—“ephethereal”—justice; that is, a portmanteau of ephemeral and ethereal. This is a justice that is short lived and ephemeral, and yet offers an impression of something not of this world, something ethereal. Drawing on my work on listening to gentrification in Washington, DC, I consider how sound invokes this ephethereal justice and offers us the tools to explore the temporal and spatial contours of liberation.

Pathos, Fall 2024, Portland State University. Student Publications Board

Pathos

Editor: Adriana Stanzione

Associations Of County-Level Social Determinants Of Health With Covid-19 Related Hospitalization Among People With Hiv: A Retrospective Analysis Of The Us National Covid Cohort Collaborative (N3c), Jessica Y. Islam, Eric Hurwitz, Dongmei Li, Marlene Camacho-Rivera, Jing Sun, Sandra Safo, Jennifer M. Ross, Shukri Hassan, Elaine L. Hill, Cara Varley, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Individually, the COVID-19 and HIV pandemics have differentially impacted minoritized groups due to the role of social determinants of health (SDoH) in the U.S. Little is known how the collision of these two pandemics may have exacerbated adverse health outcomes. We evaluated county-level SDoH and associations with hospitalization after a COVID-19 diagnosis among people with (PWH) and without HIV (PWOH) by racial/ethnic groups. We used the U.S. National COVID Cohort Collaborative (January 2020-November 2023), a nationally-sampled electronic health record repository, to identify adults who were diagnosed with COVID-19 with HIV (n = 22,491) and without HIV (n = 2,220,660). We …

Religious Ideology Affecting The Political Behavior Of The Taliban Movement In The Administration Of The Afghan State, 1994-2021, Shaikha Harban

Jordan Journal of Applied Science-Humanities Series

The study provides an overview of the emergence of the Taliban movement and its ideology, the background of the Taliban's rise to power in Afghanistan, and the factors influencing the Taliban's management of the Afghan state. The internal environment, including the challenges facing Afghan society, along with external challenges posed by the international community, affected the political behavior of the movement. This movement possesses a strong organizational capacity, which has enabled it to persist in its operations and combat in Afghanistan. This influence is reflected in how the movement managed both its internal and external affairs, allowing it to build …

The Impact Of The Flipped Learning Strategy On Enhancing Academic Achievement And Increasing Motivation Among Students At King Abdullah Ii Ibn Al Hussein School – Ajloun Governorate, Feras Aliwa

Jordan Journal of Applied Science-Humanities Series

This study aims to examine the impact of the flipped learning strategy on developing achievement and increasing motivation among vocational secondary first-grade students in management and occupational safety at King Abdullah II ibn Al-Hussein Secondary Comprehensive School for Boys in Ajloun Governorate. To achieve the objectives of the research, a quasi-experimental approach was used as it was deemed suitable for the study. The sample consisted of 50 vocational secondary first-grade students selected through purposive sampling. Two divisions were then chosen randomly from among five divisions and were divided into two groups. The experimental group consisted of 25 students who studied …

The Contradiction Of Self-Perception And Defense Mechanisms In A Sample Of Infertile Women, Aseel Al-Shami, Rami Tashtoush

Jordan Journal of Applied Science-Humanities Series

The study aimed to identify the relationship between self-discrepancy and defense mechanisms in a sample of infertile women and the correlation between them. The study sample consisted of 205 infertile women, chosen using a convenience sampling method. The results indicated a high degree of self-discrepancy among these women, as well as a medium degree of defense mechanisms use. Furthermore, the study found a statistically significant relationship between self-discrepancy and defense mechanisms among infertile women. The study recommends the necessity of providing counseling programs for infertile women to reduce self-discrepancy and decrease the use of defense mechanisms.

A Proposed Educational Model For The Implementation Of Electronic Management By Public School Principals In The Capital (Amman), Aseel Al-Jabr, Adnan Al-Adayleh, Bashar Al-Saleem

Jordan Journal of Applied Science-Humanities Series

The study aims to present a proposed educational model for implementing electronic management by the principals of public schools in the capital governorate, Amman. The study sample consists of 316 principals (both males and females) selected using the stratified random sampling method from the study population. The descriptive-analytical approach is utilized. The results of the study show that the level of principals' implementation of electronic management in public schools, in the current situation, is at a medium level, with an arithmetic mean of 2.81. However, statistically significant differences are attributed to the effect of gender, favoring females, educational qualification, favoring …

The Degree Of Achievement Of The Arab Reading Challenge Project For Students’ Reading Comprehension Skills From The Viewpoint Of Arabic Language Teachers In The Bani Obaid District Directorate, Eman Al-Matlaq

Jordan Journal of Applied Science-Humanities Series

The purpose of the study is to investigate the degree to which the Arab Reading Challenge project achieved the reading comprehension skills of students from the perspective of Arabic language teachers in the Bani Obaid District Directorate. The study followed the descriptive survey method through a questionnaire that consisted of (30) items and distributed to a sample of (200) male and female teachers. The results showed that the arithmetic averages ranged between (3.19-3.29) with a medium degree of appreciation, where the level of literal comprehension came in the first rank, while the level of gastronomic comprehension came in the last …

The Degree To Which Art And Music Education Supervisors Practice The Clinical Supervision Model From The Perspective Of Art And Music Education Teachers In The Directorate Of Education For The Qasabat Irbid District, Manar Masadeh

Jordan Journal of Applied Science-Humanities Series

The study aimed to identify the degree to which art and music supervisors practice the clinical supervision model from the perspective of art and music teachers in the Directorate of Education of the Qasabat Irbid District, as well as to understand the effect of gender and years of experience on that degree. The study sample consisted of 83 male and female public-school teachers in the Irbid district during the second semester of the 2021-2022 academic year. The study used the descriptive survey method, and a questionnaire was adopted as the tool for collecting the necessary data to achieve the study's …

The Extent To Which Secondary School Principals In Ajloun Governorate Practice Ethical Values Considering Islamic Educational Thought From The Teachers' Perspective, Ali Al-Zghoul, Omar M. Khasawneh

Jordan Journal of Applied Science-Humanities Series

The purpose of this study was to identify the degree to which secondary school principals in Ajloun Governorate practice moral values considering Islamic educational thought, from the perspectives of randomly selected teachers. The study sample consisted of 311 male and female teachers who were randomly selected, and personal interviews were conducted. The descriptive analytical technique was employed, and a questionnaire was used as a tool for data collection. The study findings indicated that school principals practice Islamic moral values to a moderate extent. The findings also showed that there were no statistically significant differences at the level of statistical significance …

Arabic Language Learning Strategies Of Non-Native Speakers At Yarmouk University, Haneen Jawarneh

Jordan Journal of Applied Science-Humanities Series

The present study aimed at revealing the degree of Arabic language learning strategies of non-native speakers at Yarmouk University. To achieve the objectives of the study, the researcher used the scale of language learning strategies (SILL), derived from the compilation of Oxford (1990). The scale consisted of (50) items distributed to six areas: Memory strategies, Cognitive strategies, Compensation strategies, Metacognitive strategies, Affective strategies, and social strategies. A random sample of (87) non-Arabic speaking male and female students who are enrolled in the Bachelor of Arabic Language and Literature program and have reached a fourth-year level at Yarmouk University was chosen. …

An Educational Guide For Principals Of Public Schools To Enhance The Digital Culture Among Public School Students In The Capital Amman, Maram Otaiwi, Bashar Al-Saleem

Jordan Journal of Applied Science-Humanities Series

The study aimed to propose an educational guide for the principals of public schools to enhance electronic culture among students in public schools in the capital, Amman. The study adopted the descriptive analytical method for its relevance to the nature of the study. The research focused on the academic year 2019/2020 in Jordan. The results of the study showed that the concept of electronic culture ranked first with the highest arithmetic average of 3.95, indicating a high degree of importance. Meanwhile, dealing with modern communication technology ranked last, with an average of 3.84, also indicating a high degree of importance. …

The Impact Of Entrepreneurial Orientation On The Success Of Small Jordanian Enterprises: The Moderating Role Of Government Support During The Coronavirus Pandemic, Duha Al-Adwan, Sahar Abu Bakir

Jordan Journal of Applied Science-Humanities Series

The study aimed to test the impact of entrepreneurial orientation, with its dimensions of risk-taking, autonomy, and proactiveness, on the success of Jordanian small projects, measured by creativity and innovation, growth, and reputation. It also examined the moderating role of government support during the Corona pandemic. The study relied on a quantitative, descriptive, and analytical approach. The study population comprised all licensed projects financed by the Women’s Fund for Microfinance during the pandemic, totaling 790 projects. A random sample of 260 projects was selected to represent the study sample. The sampling unit consisted of project owners or managers. A questionnaire …

The Militarization Of The Seas Hot Spots In The Third Millennium System And The Struggle For Hegemony Between The Great Powers (America, Russia, And China): Justifications And Consequences, Basma Tom

Jordan Journal of Applied Science-Humanities Series

The study aims to identify the most prominent militarized seas and how they have become hot spots in the conflict among major powers (America, Russia and China), the justifications for the competition over them, and to clarify the repercussions of the militarization of the seas and the complexity of the conflict among these major powers on the contemporary international system. Both the descriptive analytical method and the systems analysis method were used to study the subject. The study concluded that the pursuit of militarizing the seas by the great powers has turned them into hot spots, potentially bringing international relations …

The Role Of Educational Councils In Facilitating School Administration Work In Public Schools In Ajloun Governorate As Perceived By School Principals, Sharifa Freihat, Maan Al-Ayasrah

Jordan Journal of Applied Science-Humanities Series

The study aimed to identify the role of educational councils in facilitating school administration work in public schools in Ajloun Governorate as perceived by school principals. The study population consisted of all public-school principals in Ajloun Governorate during the academic year 2021-2022, which included 128 principals. The study sample consisted of 104 principals, chosen by simple random sampling. The descriptive survey method was used, and a questionnaire served as the data collection tool to achieve the study's objectives. The results showed that the role of educational councils in facilitating school administration work in Ajloun Governorate was perceived by school principals …