Digital Commons Network^™

Resistance To Acetyl Coenzyme A Carboxylase (Accase) Inhibitor In Lolium Multiflorum: Effect Of Multiple Target-Site Mutations, Gulab Rangani, Ana Claudia Langaro, Shilpi Agrawal, Reiofeli Algodon Salas-Perez, Juan Camilo Velasquez, Christopher E. Nelson, Nilda Roma-Burgos

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Italian ryegrass (Lolium multiflorum Lam.) is a persistent weed species that poses significant management challenges in key agricultural crops such as wheat, corn, cotton, and soybean. This study investigated the prevalence of resistance to ACCase inhibitor herbicides, specifically diclofop and pinoxaden, among field-collected Italian ryegrass populations. The survey revealed widespread resistance to diclofop and emerging cross-resistance to pinoxaden. To elucidate the physiological mechanism of ACCase herbicide resistance, we investigated mutations in the carboxyl-transferase (CT) domain of the ACCase enzyme, a critical region for herbicide sensitivity. Using dCAPS assays and CT domain sequencing, several known resistance-conferring mutations were detected in …

Interventions To Improve Or Maintain Activity Of Daily Living Performance In Adults With Dementia: A Systematized Review, Abbey J. Seevers, Tristen F. Toelle, Tate M. Pfeifer, Jake D. Cera, Danielle Westmark, Stacy Smallfield, Molly Whitlow

Student Systematized Reviews: Occupational Therapy

Importance: Dementia is a progressive cognitive disorder that leads to the degradation of one’s abilities until they are dependent for all activities of daily living (ADLs) (Andersen et al., 2004). There’s an increasing importance to search for effective ways to preserve independence in ADLs and quality of life for adults with dementia (Weng et al., 2019).

Objective: To identify effective occupational therapy (OT) interventions for maintaining or improving ADL performance among adults with dementia.

Data Sources: PubMed, CINAHL, PsycINFO. This search was conducted by a medical librarian.

Design: Inclusion criteria encompassed interventions within the scope of OT, at least one …

Effectiveness Of Interventions In The Scope Of Occupational Therapy For Mental Health In Children And Adolescents: A Systematized Review, Shawn Macdonald, Jaden Siegle, Cheyney Loper, Simone Regnier, Danielle Westmark, Stacy Smallfield, Molly Whitlow

Student Systematized Reviews: Occupational Therapy

Importance: 1 in 5 children in the US have a mental health disorder (Larson et al., 2017) which affects health across the lifespan, including engagement in school and play (Rizvi et al., 2024).

Objective: This systemized review explored literature about the effectiveness of mental health interventions for children and adolescents within the occupational therapy (OT) scope of practice.

Data Sources: A medical librarian searched articles from 2019-2024 that were retrieved from PubMed, CINAHL, and PsycINFO.

Study Selection and Data Collection: Studies were included if the outcome measures addressed mental health, interventions were within the scope of OT, participants were children …

Assessing Functional Abilities In A Memory Disorder Population: A Comparison Of Self-Report, Informant-Report, And Performance-Based Measures, Kevin Andrew Murray

Theses and Dissertations

Objective: Accurate assessment of daily functioning is critical for deriving a correct diagnosis and facilitating effective patient care. While collateral reports from a reliable informant can elucidate patients’ functional capacities, they may be susceptible to misappraisals of functional status. Similarly, patients with limited insight may be prone to misjudging their functional abilities. Performance-based measures of adaptive functioning may detect subtle declines in daily functioning overlooked by self- and informant-report measures. However, these measures may be limited in terms of ecological validity. The current study investigated the association between a performance-based measure of daily functioning and patients’ and informants’ ratings of …

The Relationship Between Health Anxiety, Health Information Seeking Behaviors, And Healthcare Outcomes, Rima Malkan

Theses and Dissertations

The relationship between health anxiety and health information-seeking behaviors (HISB) suggests a possible bidirectional or reciprocal relationship, suggesting that health anxiety leads to HISB and HISB exacerbates health anxiety. The motivations for individuals seeking different types of health information vary and may be impacted by numerous factors that lead to particular health outcomes. However, the impact of these collective variables on healthcare outcomes has not been extensively investigated. The current study aimed to bridge this gap in the literature. The study sample consisted of 133 individuals ages 20-77 years who had varying levels of health anxiety. Results suggested that those …

Do Parents Know Best: The Impact Of Parental Sleep Knowledge And Related Factors On Sleep In Children With Neurodevelopmental Disorders, Rachel Nicole Chavez

Theses and Dissertations

Sleep problems are a common concern reported by parents of children with neurodevelopmental disorders (NDD). The prevalence of sleep disorders in those with NDD have been reported as high as 86% compared to 25% of typically developing children (Horwood et al., 2019, Robin-Shelton, 2016). These sleep problems can have detrimental effects on cognition, development, behavior, emotion regulation, and physical health. Existing research demonstrates a significant relationship between a child’s sleep disturbances and their parents’ sleep quality and level of parenting stress. This study aimed to identify the gaps in parental sleep knowledge and examined how parent sleep quality and parental …

Out Of Left Screen: Factors Impacting Well-Being In Digital And Physical Collegiate Athletes, Jessica Poskus

Theses and Dissertations

Competitive video gaming, or “esports,” has quickly become a popular college extracurricular. Its classification as a varsity sport on many campuses reflects a broader shift in cultural conceptualizations and perceptions of athleticism. As esports continue to evolve in today’s increasingly digital world, new professional leagues emerge, and viewership rivals that of traditional physical sports. Esports can be a gateway for unique opportunities for college students; however, it may also pose some challenges. This study explored differences between digital and physical athletes, who must balance their chosen activity with other collegiate responsibilities, including academic, social, and physical health. Physical sports and …

Patient-Provider Communication About Cigarette And E-Cigarette Use During Pregnancy: Adaptation And Validation Of Frequency And Quality Of Communication Measures Among A Sample Of Pregnant Patients, Emily M. Richardson, Eric Schisler, Page D. Dobbs

The Eleanor Mann School of Nursing Faculty Publications and Presentations

Introduction:
Quality of patient–provider communication regarding tobacco use may encourage cessation that could lead to improved health outcomes for mothers and children. However, currently there are no validated measures of frequency and quality of patient–provider communication about cigarettes and e-cigarettes. The objective of this study was to adapt and validate measures of frequency and quality of patient–provider communication about smoking and e-cigarette use among a sample of pregnant mothers who currently smoked.

Methods:
An online sample of US pregnant women who reported past 30-day smoking were recruited to complete a cross-sectional, online survey (n=267). An exploratory factor analysis examined the …

Abstinence Beliefs In Early Adolescence And Sexual Risk Behavior Two Years Later, Shristi Bhochhibhoya, Briana Edison, Elizabeth R. Baumler, Christine M. Markham, Susan T. Emery, Melissa F. Peskin, Ross Shegog, Robert C. Addy, Jeff R. Temple, Dennis E. Ready

Health, Human Performance and Recreation Faculty Publications and Presentations

Introduction

The United States has the highest teen pregnancy rate and sexually transmitted infection rates among developed countries. One common approach that has been implemented to reduce these rates is abstinence-only-until-marriage programs that advocate for delaying sexual intercourse until marriage. These programs focus on changing adolescents' beliefs toward abstinence until marriage; however, it is unclear whether adolescents' beliefs about abstinence predict their sexual behavior, including sexual risk behavior (SRB). An alternative approach may be encouraging youth to delay their sexual debut until they reach the age of maturity, but not necessarily until marriage.

Methods

To address this question, we compare …

A Step Into Khmer’S Double Negation Mystery: Clause-Final Marker ទេ[Te:] As Negative Polarity Focus, Panhavoan Reth , '25

Senior Theses, Projects, and Awards

In Khmer, basic negation is formed using two negation elements: the preverbal marker មិន [mɨn] and the clause-final marker ទេ[te:]. However, there are cases where [te:] is optional with the utterance still retaining its negative meaning; when it is present, it is claimed that the utterance can have two readings: plain negation and emphatic negation (Saparova, 2020). Thus, there is speculation as to what function [te:] serves and what it contributes to the semantic meaning of a sentence. This thesis examines the optionality of [te:] through the lens of polarity focus, drawing on Wilder’s (2013) and Goodhue’s (2018, 2022) observations. …

Assessing Factors Of Adherence And Efficacy: A Randomized Controlled Trial Of A Fully Automated Self-Help A-Ebt Website, Leila K. Capel, Emily M. Bowers, Mckenzie R. Becker, Marisa P. Davis, Michael E. Levin, Michael P. Twohig

Psychology Faculty Publications

Treatment for trichotillomania is notably limited, preventing suffering individuals from having access to treatment. To address this need, researchers have developed and tested asynchronous online interventions for adults with trichotillomania. A factor that may impact the efficacy of these programs is the use of phone check-ins (or similar coaching support) to improve treatment adherence in website treatment delivery. In the current study we evaluated the role of check-ins on treatment adherence and efficacy of a website delivering acceptance and commitment therapy-enhanced behavior therapy (A-EBT). A sample of 101 adults with trichotillomania were randomly assigned to an A-EBT web-based intervention with …

Masthead, Volume 46 (2024-2025)

Cardozo Law Review

No abstract provided.

Women On Death Row In The United States, Sandra Babcock, Nathalie Greenfield, Kathryn Adamson

Cardozo Law Review

This Article presents a comprehensive study of forty-eight persons sentenced to death between 1990 and 2022 who were legally recognized as women at the time of their trials. Our research is the first of its kind to conduct a holistic and intersectional analysis of the factors driving women’s death sentences. It reveals commonalities across women’s cases, delving into their experiences of motherhood, gender-based violence (“GBV”), and prior involvement with the criminal legal system. We also explore the nature of the women’s crimes of conviction, including the role of male codefendants and the state’s use of aggravating factors. Finally, we reveal …

Privacy Law’S Role In An Information Economy, Sari Mazzurco

Cardozo Law Review

What do we lose when we lose our privacy? A slew of recently enacted state laws suggest that the loss of privacy is merely a loss of individual choice in the market exchange of services for personal information. This Article argues that a loss of privacy risks something greater: the collapse of complex and fluid social identity. Without privacy, individuals cannot nurture their own senses of self because they are no longer free to try on different social roles across diverse relationships. Pervasive, private data collection threatens multifaceted selfhood by eliminating the boundaries that make social roles distinct and hindering …

The Forever Family’S Legal Loophole: A 50-State Survey On Adoption Dissolution, Kira Kilstein

Cardozo Law Review

Adoption is said to be “forever”—longing parents fulfill their dream of parenthood and children get a “forever family.” While the legal system intends for adoptive parent-child relationships to be permanent, a happily-ever-after ending is elusive when adoptions are enabled to fail. In the United States, each state can set its own standard for when courts may grant a request to dissolve an adoption, as well as time limits within which a parent may ask the court to vacate the adoption decree. This legal loophole, known as adoption dissolution, has been met with controversy about the permissibility of parents giving up …

A Missed Opportunity: Clarifying Presidential Power Under The Procurement Act, Anthony Porcelli

Cardozo Law Review

In late 2021, President Biden relied on the Procurement Act to sign an Executive Order effectively requiring every employee of any private company that contracts with the federal government to be fully vaccinated for COVID-19. While the mandate was ultimately rescinded less than two years later, it produced four inconsistent federal circuit court opinions that together expose the problems with existing judicial frameworks for analyzing executive authority under the Procurement Act.

This Note explores the growth of the federal procurement industry, the evolution of executive orders under the Procurement Act, and the existing jurisprudence for executive power under the Act. …

Theistic Illiberal Constitutionalism: A Review Of Adrian Vermeule’S Common Good Constitutionalism, Kyron J. Huigens

Articles

Adrian Vermeule’s Common Good Constitutionalism drew a remarkable amount of attention from constitutional law scholars when it was published in 2020. About eighteen months later, Vermeule published a piece complaining that the critics had missed the point, that they had ignored the natural law jurisprudence that grounds the work. He was correct. This Review addresses Vermeule’s natural law jurisprudence, emphasizing the fact that it is a religious natural law jurisprudence. His arguments are in the tradition of ScholasticismAristotelian logic incorporated into Christian theology by St. Thomas Aquinas. Scholasticism is a remarkably weak foundation for constitutional jurisprudence. It is a vast …

Type I Ifn Signaling In The Absence Of Irgm1 Promotes M. Tuberculosis Replication In Immune Cells By Suppressing T Cell Responses, Sumanta K Naik, Michael E Mcnehlan, Yassin Mreyoud, Rachel L Kinsella, Asya Smirnov, Chanchal Sur Chowdhury, Samuel R Mckee, Neha Dubey, Reilly Woodson, Darren Kreamalmeyer, Christina L Stallings

2020-Current year OA Pubs

Polymorphisms in the IRGM gene are associated with susceptibility to tuberculosis in humans. A murine ortholog of Irgm, Irgm1, is also essential for controlling Mycobacterium tuberculosis (Mtb) infection in mice. Multiple processes have been associated with IRGM1 activity that could impact the host response to Mtb infection, including roles in autophagy-mediated pathogen clearance and expansion of activated T cells. However, what IRGM1-mediated pathway is necessary to control Mtb infection in vivo and the mechanistic basis for this control remains unknown. We dissected the contribution of IRGM1 to immune control of Mtb pathogenesis in vivo and found that Irgm1 deletion leads …

The Promise And Perils Of Smart (City) Bots As Educational Tools, Thomas Menkhoff, Siew Ning Kan, Shaohui Foong

Research Collection Lee Kong Chian School Of Business

Written from an educator’s perspective, the paper aims to examine the increasing use of chatbot technology capable of answering user queries in various fields such as commerce, public service delivery, urban areas, higher education etc. by simulating human conversation through text messages or voice commands. We analyse why smart bots have become popular technologies in the context smart cities; shed light on different types of bots (chatbots, large language models such as ChatGPT, flying bots); and explain how we use bots as teaching tool in an introductory AI for business course. A key argument putting forward is that smart bots …

Mapping The Threat Environment Of Southern California’S Elected Officials, John Porten, Rachel Locke

Kroc IPJ Research and Resources

Are threats towards and harassment of public officials a problem? Some characterize the issue as one of free speech; strenuous criticism of local officials is required for democracy to function. Others argue that local elected officials and the media are simply seeking attention or blowing a small problem out of proportion. In other spaces, the case is made that democracy in America is broken, that governance at the local level can no longer function, and that security risks are rampant. Those studying the issue have gathered data that point to more insidious effects, including the disenfranchisement of voters, shifting representation …

Green Utopias: A Possible Green Ground For Performing Arts Training, Renee Newman, Alexa Taylor, Luke Cowling, Jason Garbenis, Tom Heath, Fleur Kingsland, Vahri Mckenzie, Jeremy Neideck, Richard Reddrop, Simon Stewart

Research outputs 2022 to 2026

No abstract provided.

Masthead

California Regulatory Law Reporter

No abstract provided.

California State Athletic Commission, Celeste Franco, Marcus Friedman

California Regulatory Law Reporter

No abstract provided.

Kenneth Koch, Cincinnatian, Poet Of Confetti, Lew Klatt

University Faculty Publications and Creative Works

Essay. “Kenneth Koch, Cincinnatian, Poet of Confetti,” in The Cincinnati Review 20.2, Fall 2023

Pkmyt1 Is A Marker Of Treatment Response And A Therapeutic Target For Cdk4/6 Inhibitor-Resistance In Er+ Breast Cancer, Anran Chen, Beom-Jun Kim, Aparna Mitra, Craig T Vollert, Jonathan T Lei, Diana Fandino, Meenakshi Anurag, Matthew V Holt, Xuxu Gou, Jacob B Pilcher, Matthew P Goetz, Donald W Northfelt, Susan G Hilsenbeck, C Gary Marshall, Marc L Hyer, Robert Papp, Shou-Yun Yin, Carmine De Angelis, Rachel Schiff, Suzanne A W Fuqua, Cynthia X Ma, Charles E Foulds, Matthew J Ellis

Faculty, Staff and Students Publications

Endocrine therapies (ET) with cyclin-dependent kinase 4/6 (CDK4/6) inhibition are the standard treatment for estrogen receptor-α-positive (ER+) breast cancer, however drug resistance is common. In this study, proteogenomic analyses of patient-derived xenografts (PDXs) from patients with 22 ER+ breast cancer demonstrated that protein kinase, membrane-associated tyrosine/threonine one (PKMYT1), a WEE1 homolog, is estradiol (E2) regulated in E2-dependent PDXs and constitutively expressed when growth is E2-independent. In clinical samples, high PKMYT1 mRNA levels associated with resistance to both ET and CDK4/6 inhibition. The PKMYT1 inhibitor lunresertib (RP-6306) with gemcitabine selectively and synergistically reduced the viability of ET and palbociclib-resistant ER+ breast …

Discordance Between Aptt And Anti-Xa In Monitoring Heparin Anticoagulation In Mechanical Circulatory Support, Song Li, Ang Li, Jennifer A Beckman, Christopher Kim, Marian A Granich, John Mondin, Daniel E Sabath, David A Garcia, Claudius Mahr

Faculty, Staff and Students Publications

AIMS: It is unclear whether activated partial thromboplastin time (aPTT) or anti-Xa is more accurate for monitoring heparin anticoagulation in mechanical circulatory support (MCS) patients. This study investigates the relationship between aPTT and anti-Xa in MCS patients and identifies predictors of discordance.

METHODS AND RESULTS: aPTT and anti-Xa were simultaneously measured in a prospective cohort of MCS patients receiving unfractionated heparin at a tertiary academic medical centre. Therapeutic aPTT and anti-Xa levels were 60-100 s and 0.3-0.7 IU/mL, respectively, and concordance was defined as both levels being subtherapeutic, therapeutic, or supratherapeutic. To identify predictors of discordance, both a machine learning …

Effects Of Perceived Environmental Quality And Psychological Status On Outdoor Thermal Comfort: A Panel Study In Southern China, Cho Kwong Charlie Lam, Haonan Pan, Weixiao Nie, Xiaohui Li, Jie Wu, Zhe Yin, Jiejie Han

School of Geography, Earth and Environmental Sciences

Urban residents are exposed to multiple environmental stimuli. Past studies have examined the influence of heat stress on outdoor thermal comfort, but the cross-modal effects of various sensory stimuli on outdoor thermal comfort remain unclear. This study used chi-square tests and logistic regression to examine the cross-modal effects of perceived environmental quality (acoustic, visual and air quality) and psychological status (irritability, perceived tiredness) on outdoor thermal comfort. We conducted thermal walk experiments in Guangzhou, China, in September and October 2022. This panel study consisted of mobile environmental sensors and thermal comfort surveys by fourteen university students on three walking routes, …

Tracking Implementation Of Shark-Related Measures And Actions In The Mediterranean Region In The Context Of International Law, Jason Lowther, Lydia Koehler

School of Law, Humanities and Social Sciences

We present national implementation progress on international and regional legal obligations up to 2020 and discuss recent developments in shark conservation management in the region. This study provides insights into the complexity of implemented measures and actions related to shark conservation and fisheries management, governed by various legal instruments. Measures were primarily identified through regional fisheries management organisations (RFMO) reports, reports of Focal Point meetings under the Barcelona Convention, and national reports under the Convention on Biological Diversity (CBD) and the Convention on Migratory Species (CMS). A total of 208 implemented measures across different categories were found. The most common …

Interpregnancy Maternal Weight Change Is Not Associated With Offspring Weight And Obesity At Age 2 Years, Kate Maslin, Lieveke Ameye, Diederik Vancoppenolle, Anne Rochtus, Hanne Van Uytsel, Jill Shawe, Roland Devlieger, Annick Bogaerts

School of Nursing and Midwifery

Background: Weight retention between pregnancies is associated with increased risk of perinatal complications, but it is unclear whether there is an association with offspring weight status. This study aimed to determine whether maternal interpregnancy weight change is associated with offspring overweight/obesity, controlling for confounding variables. Subjects/methods: Routinely collected linked data from perinatal and child datasets, in Flanders, Belgium were used. Women having their first and second live births between 2009–2018 were included. The association between maternal interpregnancy weight change and overweight/obesity in the second child at 2 years was examined by logistical regression models. Results: A total of 33,172 women …

Publisher Correction: Detection Of Mosaic And Population-Level Structural Variants With Sniffles2, Moritz Smolka, Luis F Paulin, Christopher M Grochowski, Dominic W Horner, Medhat Mahmoud, Sairam Behera, Ester Kalef-Ezra, Mira Gandhi, Karl Hong, Davut Pehlivan, Sonja W Scholz, Claudia M B Carvalho, Christos Proukakis, Fritz J Sedlazeck

Faculty, Staff and Students Publications

This corrects the article "Detection of mosaic and population-level structural variants with Sniffles2" on page 1571.