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Understanding Chronic Bodily Pain Across Multisystemic Illnesses: A Comparative Analysis Using Exploratory Factor Analysis And Invariance Testing, Suvetha Ravichandran Jul 2026

Understanding Chronic Bodily Pain Across Multisystemic Illnesses: A Comparative Analysis Using Exploratory Factor Analysis And Invariance Testing, Suvetha Ravichandran

Theses and Dissertations from DePaul University

Chronic pain is a debilitating symptom that often remains under-researched and poorly treated, particularly for those with multisystemic conditions. This study explored the shared and distinct experiences of chronic bodily pain across four multisystemic illnesses: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Multiple Sclerosis (MS), Post-Polio Syndrome (PPS), and Long COVID. Comparative exploratory factor analysis (EFA) and invariance testing were used to examine commonalities and differences in underlying pain experiences for those with the above diagnoses as well as healthy controls based on their responses to pain items from the DePaul Symptom Questionnaire-1 (DSQ-1). A total of 3,724 participants were included: 2,403 …


Analysis Of Clinical Health Worker Notes With Explainable Artificial Intelligence For A Better Perspective In Preventing Readmission, Christopher Scott Klimp Jul 2026

Analysis Of Clinical Health Worker Notes With Explainable Artificial Intelligence For A Better Perspective In Preventing Readmission, Christopher Scott Klimp

Theses and Dissertations from DePaul University

Emergency Department (ED) readmissions remain a major challenge for healthcare systems, affecting both patient care quality and financial costs. Most prediction models depend largely on structured data from clinical tools that assign points to a small set of predefined factors – such as comorbidities, previous hospital visits, and behaviors such as smoking and drinking – and then sum those points to produce an overall risk score. These point-based tools leave out important information from Social Determinants of Health and a wealth of information from Community Health Workers (Community health workers (CHWs), trusted members of a community who help connect people …


Using Recommender Systems To Help Revitalize Local News, Payam Pourashraf Jul 2026

Using Recommender Systems To Help Revitalize Local News, Payam Pourashraf

Theses and Dissertations from DePaul University

Local news outlets have experienced steep declines in readership as national and global online news sources have expanded and consolidated audience attention. Because many local media companies rely primarily on subscription-based business models, they must increase user engagement and provide clearer value to local subscribers. Personalization and recommender systems offer one promising path toward this goal. However, many recommender systems assume that a user’s past behavior can be summarized in a single unified profile. In practice, preferences are often context-dependent: the same person may prefer different content depending on geography, time, task, or situation. Local news offers a socially important …


Relationship Of Early Rapid Weight Loss To Efficacy And Safety Of Tirzepatide And Semaglutide For Obesity: Surmount-5 Post Hoc Analysis, Louis J Aronne, Deborah B Horn, Alexander D Kokkinos, Beverly L Falcon, Hui Wang, Hunter T Hoffmann, Clare J Lee, Julia P Dunn Jul 2026

Relationship Of Early Rapid Weight Loss To Efficacy And Safety Of Tirzepatide And Semaglutide For Obesity: Surmount-5 Post Hoc Analysis, Louis J Aronne, Deborah B Horn, Alexander D Kokkinos, Beverly L Falcon, Hui Wang, Hunter T Hoffmann, Clare J Lee, Julia P Dunn

Faculty, Staff and Student Publications

Background: A knowledge gap remains in how the rate of body weight reduction impacts efficacy and safety of obesity management medications. This SURMOUNT-5 post hoc analysis aimed to define rapid responders and evaluated efficacy and safety of tirzepatide versus. semaglutide in rapid responders versus non-rapid responders.

Methods: Rapid responders and non-rapid responders were defined as participants that obtained ≥ 15% and < 15% body weight reduction by Week 24, respectively. Baseline characteristics, and proportion of participants achieving body weight reduction thresholds by Week 72 were assessed. End-of-study safety and gastrointestinal adverse events measures were summarized.

Results: Overall, 32.3% were rapid responders (tirzepatide: 44%, semaglutide: 21%). The proportions of participants achieving body weight reduction thresholds by Week 72 were higher for rapid responders versus non-rapid responders. Safety trends for tirzepatide and semaglutide were similar between …


Advancing Imbalanced Classification Through Representation Learning, Morteza Mohammady Gharasuie Jul 2026

Advancing Imbalanced Classification Through Representation Learning, Morteza Mohammady Gharasuie

Computer Science Theses & Dissertations

Real-world datasets frequently exhibit severe class imbalance, where certain categories are significantly underrepresented relative to others, leading standard empirical risk minimization to bias learning toward majority classes and degrade performance on minority categories. This dissertation addresses imbalanced classification across both structured tabular data and long-tailed visual recognition by developing methods that improve representation learning and decision reliability under skewed distributions. For tabular data, it introduces Conditional Probability Representation (CPR), a target-based encoding framework that embeds feature–label relationships directly into the representation space, enhanced by a progressive feature upgrading mechanism for semi-supervised settings and a class-frequency–aware extension that improves robustness to …


A Language Model’S Capability To Make Reasoned Decisions In Administrative Law, Robert Diab Jul 2026

A Language Model’S Capability To Make Reasoned Decisions In Administrative Law, Robert Diab

Dalhousie Law Journal

This paper calls into question a common set of assumptions about the use of artificial intelligence in administrative law in Canada. While some assume that AI (AI) may be useful for assisting a decision-maker where core rights are affected, the prevailing view is that it cannot be relied upon to make final decisions, due mainly to functional limitations: AI cannot give reasons and its outcomes are fraught with bias and opacity that cannot be overcome. The prevailing view, however, took shape in response to earlier, more limited forms of AI. Large language models can be used in a way that …


Privacy, Paternalism, And Standing In Health Professions Regulation, Anthony Sangiuliano Jul 2026

Privacy, Paternalism, And Standing In Health Professions Regulation, Anthony Sangiuliano

Dalhousie Law Journal

When investigating whether a doctor has behaved unethically while treating a patient, professional regulatory colleges may search patients’ confidential medical records without patients’ consent. I argue that this practice is not paternalistic, nor does it usurp patients’ standing to decide for themselves whether to sacrifice their privacy to hold the doctor to account for professional wrongdoing. College investigations that non-consensually invade patient privacy do not express disrespect for patients’ agency because they aim to mitigate harm to the broader public. Unlike criminal prosecutions of doctors which uphold moral values pervading the public at large, college investigations enforce ethical standards within …


A Qualitative Study Of Key “Regulatory” Factors Influencing Patient Access To Medical Assistance In Dying In Canada, Ruthie Jeanneret, Eliana Close, Jocelyn Downie, Ben P. White Jul 2026

A Qualitative Study Of Key “Regulatory” Factors Influencing Patient Access To Medical Assistance In Dying In Canada, Ruthie Jeanneret, Eliana Close, Jocelyn Downie, Ben P. White

Dalhousie Law Journal

Medical assistance in dying (“MAiD”) was legalized federally in Canada after the landmark case, Carter v Canada (AG), 2015 SCC 5. Bill C-14 introduced a federal legislative framework for MAiD in 2016, which was amended by Bill C-7 in 2021. Some Bill C-7 amendments directly responded to the decision in Truchon c Canada (PG), 2019 QCCS 3792. Other amendments responded to several factors identified as barriers to patient access, including the requirement for two independent witnesses, the 10-day reflection period, and the requirement to provide final consent at the time of administration of MAiD medication. However, emerging literature identifies that …


Aboriginal Title In Former French Colonies: Reaching Back Before The Assertion Of French Sovereignty, Ghislain Otis Jul 2026

Aboriginal Title In Former French Colonies: Reaching Back Before The Assertion Of French Sovereignty, Ghislain Otis

Dalhousie Law Journal

A substantial part of Canada was colonized by France well before the British arrival in the mid-eighteenth century. This article examines the effect of the assertion of French sovereignty on the Aboriginal title regime recognized under British-Canadian law.

In Part I, the author identifies a trend in the jurisprudence whereby courts assess the Indigenous territorial situation existing at the time of the British assertion of sovereignty, rather than at the time of French sovereignty, for the purpose of applying the exclusive control criterion underlying the recognition of Aboriginal title. The author then demonstrates that this approach creates significant difficulties for …


Environmental And Socioeconomic Effects Of Roundtable On Sustainable Palm Oil Certification: A Systematic Review And Meta-Analysis, Kibrom T. Sibhatu, Matin Qaim Jul 2026

Environmental And Socioeconomic Effects Of Roundtable On Sustainable Palm Oil Certification: A Systematic Review And Meta-Analysis, Kibrom T. Sibhatu, Matin Qaim

All Peer-Reviewed Publications

Palm oil is the most widely produced and consumed vegetable oil worldwide, but its production is associated with deforestation and other environmental and social problems. Roundtable on Sustainable Palm Oil (RSPO) is the only internationally-recognized voluntary certification standard aimed at mitigating such problems. Many studies examine RSPO’s effects on particular outcomes in specific contexts, but a consolidated global assessment is lacking. Here, we systematically review the literature and identify 53 original studies covering RSPO effects in various countries of Asia, Africa, and Latin America. Where data availability permits, we also conduct meta-analysis. Results reveal that RSPO can lead to environmental …


Typicality Of Inferences Resulting From Limited Psychometric Models And Statistical Techniques Used: A Review Of Education Studies Published In Arab Journals (2016–2024), Mohammed A. A. Abulela, Mustafa Ali Khalaf Jul 2026

Typicality Of Inferences Resulting From Limited Psychometric Models And Statistical Techniques Used: A Review Of Education Studies Published In Arab Journals (2016–2024), Mohammed A. A. Abulela, Mustafa Ali Khalaf

Journal of Educational and Psychological Studies

The study assessed the typicality of inferences in educational research published in Arab journals between 2016 and 2024 by determining the prevalence of psychometric models, the statistical techniques utilized, and the extent to which their assumptions were checked. Reviewed studies included 410 articles from eleven journals. The findings indicated that most studies relied on Cronbach’s alpha for estimating score reliability (60%) without checking its assumptions, while the use of confirmatory factor analysis and item response theory was limited. Additionally, researchers predominantly relied on face validity (expert judgment) at a rate of 55.3%, reflecting limited validation efforts for achieving the quality …


Understanding The Forest School Experience: A Conceptual Exploration Of Benefits And Barriers, Ziad F. Dabaja Jul 2026

Understanding The Forest School Experience: A Conceptual Exploration Of Benefits And Barriers, Ziad F. Dabaja

Journal of Educational and Psychological Studies

Forest School, a form of outdoor nature-based education, has increasingly gained international attention, particularly, its educational and developmental benefits are well documented. While existing literature highlights positive outcomes for children, families, and educators, it also identifies a range of challenges that can hinder effective implementation. This paper adopts a conceptual study design and synthesizes findings from three peer-reviewed literature reviews, collectively examining 40 international studies, to develop an integrative concept map of the Forest School experience. Using a thematic synthesis, evidence from the reviewed studies was analyzed to identify overlapping and complementary themes, which were categorized into benefits, implementation challenges, …


Feasibility Of Using Electronic Medical Records To Identify Postdischarge Mental Health Screening Documentation In Trauma Patients., Kellie Girardot, Julie L Otte Jul 2026

Feasibility Of Using Electronic Medical Records To Identify Postdischarge Mental Health Screening Documentation In Trauma Patients., Kellie Girardot, Julie L Otte

Emergency Medicine and Trauma

BACKGROUND: Injury leads to long-term physical and mental health challenges, yet inpatient screening for post-traumatic stress disorder and depression remains inconsistent, and postdischarge mental health is poorly understood, particularly in less resourced trauma centers where emerging symptoms may go unrecognized.

OBJECTIVE: To evaluate the feasibility of using the electronic medical record to identify postdischarge mental health screening documentation in adult trauma patients within 6 months after discharge.

METHODS: This retrospective descriptive feasibility study was conducted at a midwestern US regional Level II trauma center serving a predominantly rural catchment area. Adult trauma patients admitted between January 1 and December 31, …


A Comparative Study Of Aging And Cortical Folding In Chimpanzees And Olive Baboons, William D. Hopkins, Angela M. Achorn, Michele M. Mulholland, Elizabeth R. Magden, Steven J. Schapiro, Courtney L, Fults, Jean‐Francois Mangin, Adrien Meguerditchian Jul 2026

A Comparative Study Of Aging And Cortical Folding In Chimpanzees And Olive Baboons, William D. Hopkins, Angela M. Achorn, Michele M. Mulholland, Elizabeth R. Magden, Steven J. Schapiro, Courtney L, Fults, Jean‐Francois Mangin, Adrien Meguerditchian

Anthropology Faculty Publications

In light of the evidence that nonhuman primates naturally develop Alzheimer's disease neuropathologies, there is a renewed interest in research on the comparative biology of aging, including neurological changes across the age groups in species with diverse lifespans. In this paper, we examined age‐related differences in two measures of cortical folding, mean depth and fold opening, in a sample of chimpanzees (Pan troglodytes) and olive baboons (Papio anubis). We found significant species differences in the slope and pattern of age‐related changes in cortical folding. As predicted, chimpanzees showed negative linear associations between age and mean depth and …


Research Nexus : Volume 39 – 2026, Office Of Research And Graduate Studies Jul 2026

Research Nexus : Volume 39 – 2026, Office Of Research And Graduate Studies

Office of Research and Graduate Studies

  • Researcher Spotlight
  • Research Milestones & News
  • Capacity Building Initiatives
  • Celebrating New Beginnings
  • NIH Updates & Other Resources
  • Explore New Grant Opportunities


Do I Fit In Here? How Immigrants’ Endorsement Of Social Markers Is Related To Their Wellbeing In Three Migrant Receiving Societies, Justine Dandy, Chan Hoong Leong, Adam Komisarof, Travis Lim, Krystal Perkins Jul 2026

Do I Fit In Here? How Immigrants’ Endorsement Of Social Markers Is Related To Their Wellbeing In Three Migrant Receiving Societies, Justine Dandy, Chan Hoong Leong, Adam Komisarof, Travis Lim, Krystal Perkins

Research outputs 2022 to 2026

Social markers of acceptance are the attributes seen as important for immigrants to achieve or display in order to be accepted similarly to a local-born citizen. In research on constructions of national identity, factor analysis reveals a culture-specific, two-factor structure akin to the ethnic–civic distinction observed. In this paper, we extend this work by examining the relationship between social markers of acceptance and immigrants’ well-being in three national contexts: Australia, Japan, and the U.S. Specifically, in study 1 we examined the factor structure of social markers in non-immigrant samples in each context (Australia, n = 1357; Japan, n = 2000; …


Pfas Quantification Using Solid Phase Extraction And Low Field Nuclear Magnetic Resonance (Spe-Nmr), Nicholas N.A. Ling, Ghasemi, Ella Shilliday, Masoumeh Zargar, Einar Fridjonsson, Michael L. Johns Jul 2026

Pfas Quantification Using Solid Phase Extraction And Low Field Nuclear Magnetic Resonance (Spe-Nmr), Nicholas N.A. Ling, Ghasemi, Ella Shilliday, Masoumeh Zargar, Einar Fridjonsson, Michael L. Johns

Research outputs 2022 to 2026

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that are highly resistant to biodegradation. Due to their bioaccumulation, long-term persistence, and adverse human health effects, they have been classified as organic pollutants. The leaching of PFAS into water sources has resulted in their detection in global drinking water supplies. To mitigate adverse health effects and minimise environmental damage, regulations regarding maximum allowable PFAS concentrations in water have been imposed. Traditional PFAS in water quantification methods, such as liquid chromatography–mass spectrometry (LC–MS), gas chromatography–mass spectrometry (GC–MS), and high-performance liquid chromatography (HPLC), have intrinsic limitations that pose challenges in such PFAS analysis. …


The Personality Profile Of Innovator, Entrepreneur, And Business Leader Elon Musk, Amelia Brower, Aubrey Immelman Jul 2026

The Personality Profile Of Innovator, Entrepreneur, And Business Leader Elon Musk, Amelia Brower, Aubrey Immelman

Psychology Faculty Publications

This paper presents the results of an indirect personality assessment of entrepreneur and business leader Elon Musk, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data relating to Musk were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5-TR.

The personality profile yielded by the MIDC was analyzed in accordance with interpretive guidelines provided in the MIDC and Millon Index of Personality Styles (MIPS) manuals. Musk’s primary personality patterns …


Amplifying Florida Ems Voices: Results Of The 2026 Annual Agency Survey, Michael Lozano, Claire Guadiana, Farina Klocksieben Jul 2026

Amplifying Florida Ems Voices: Results Of The 2026 Annual Agency Survey, Michael Lozano, Claire Guadiana, Farina Klocksieben

Florida Center for Emergency Medical Services Research Reports

Executive Summary

Florida EMS at a Glance

What the system said

  • Agency size shapes capacity. Larger agencies generally have more staffing flexibility, stronger wellness and data infrastructure, broader disaster coordination, and faster adoption of newer practices.
  • The workforce shortage centers on paramedics. Three in five agencies report a staffing shortage, with 58.5 percent reporting a paramedic shortage. Higher starting pay is associated with fewer vacancies, pointing primarily to a recruitment challenge.
  • Fire and non-fire agencies show different strengths. Fire departments lead in tactical readiness and dispatch-linked capabilities. Non-fire agencies more often report customer feedback systems, health information exchange participation, incentive-linked …


Irrigation Use In A Changing Landscape: A Combined Economic And Hydrologic Approach, Noormah Rizwan, Jamshid Jahali, Molly Sears, Sean Woznicki, Tao Liu, Oskar Marko, Mirjana Radulović Jul 2026

Irrigation Use In A Changing Landscape: A Combined Economic And Hydrologic Approach, Noormah Rizwan, Jamshid Jahali, Molly Sears, Sean Woznicki, Tao Liu, Oskar Marko, Mirjana Radulović

Michigan Tech Publications

Warmer temperatures and erratic rainfall patterns are threatening global water availability. Irrigation is a key risk-mitigation strategy, helping sustain crop yields under climate stress. Limited research has examined farmers' likelihood of irrigating under climate change, or the effects of large-scale irrigation expansion on future water availability, largely due to challenges in acquiring field-level irrigation data. Using an integrated econometric-hydrologic modeling approach, we investigate how short- and long-run climatic conditions shape irrigation incentives and feasibility in Serbia—an increasingly water-stressed region—and how these incentives evolve under future climate scenarios. Our econometric model identifies when and where irrigation becomes a viable option under …


Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara Jul 2026

Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara

Research outputs 2022 to 2026

This PRISMA-guided scoping review examines the use of waste materials in civil engineering as a sustainable approach to reducing environmental impacts, conserving natural resources, and supporting circular economy principles. The rapid growth of urbanization, industrialization, mining, and agricultural activities generates large amounts of waste materials, including fly ash, ground granulated blast-furnace slag, bauxite residue, mining tailings, waste rock, acid-mine drainage sludge, waste plastics, post-consumer vulcanized rubber, recycled construction materials, and agricultural ashes. The disposal of these materials often creates serious environmental and land-use problems, making their reuse increasingly important. In this context, civil engineering is one of the most promising …


Oman Society Of Emergency Medicine Conference 2026, Sultan Qaboos University Jul 2026

Oman Society Of Emergency Medicine Conference 2026, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.


Neural Network Technologies In The Automatical Control Systems Of Absorption Process For Pureficating Natural Gas, Abdishukurov Maqsudovich Shavkat Mr, Xuecheng Li Li Xuecheng Mr Jul 2026

Neural Network Technologies In The Automatical Control Systems Of Absorption Process For Pureficating Natural Gas, Abdishukurov Maqsudovich Shavkat Mr, Xuecheng Li Li Xuecheng Mr

Technical science and innovation

Analysis of methods and algorithms for synthesizing adaptive control systems for technological processes based on the neural network approach is carried out in this search. The stages of mathematical modeling of complex technological processes using neural network technology were considered. Additionally, an algorithm for solving the interpolation and extrapolation problem that arises in the training process a neural network to control system was proposed. At the final stage of this article, algorithms based on neural network technology are synthesized for the control system for the parameters of the technological process of natural gas purification by absorption


Most Bay Staters Believe Police Concealed Evidence In Read Case & Police Conduct Is Evidence Of Wider Problem 7/1/2026, Unh Survey Center Jul 2026

Most Bay Staters Believe Police Concealed Evidence In Read Case & Police Conduct Is Evidence Of Wider Problem 7/1/2026, Unh Survey Center

All UNH Survey Center Polls

In the Karen Read case, majorities of Bay Staters believe police concealed evidence in the case and believe police conduct is indicative of a wider problem with policing in Massachusetts. Generally speaking, pluralities of Massachusetts residents believe state and local police in the commonwealth do a good job protecting people from crime, treating racial and ethnic groups equally, and using the right amount of force, but four in ten believe police do a poor job holding officers responsible when misconduct occurs. Nearly all Massachusetts residents feel comfortable calling 911 when needed.


A Leadership Trait Analysis Of U.S. Vice President Jd Vance, Aubrey Immelman, Sophie J. Heck Jul 2026

A Leadership Trait Analysis Of U.S. Vice President Jd Vance, Aubrey Immelman, Sophie J. Heck

Psychology Faculty Publications

This paper presents the results of an indirect leadership trait analysis of U.S. vice president JD Vance, conducted for the purpose of anticipating Vance’s likely leadership style in a high-level executive role in politics, from the conceptual perspective of Margaret Hermann’s leadership trait analysis (LTA) model, employing an empirically based “psychodiagnostic meta-analytic” methodology.

Psychodiagnostically relevant data relating to Vance were collected from biographical sources and media reports and synthesized into a personality profile using the Hermann Leadership Trait Inventory (HLTI) — constructed expressly for the present study — which taps seven leadership trait dimensions: belief in one’s ability to control …


Operational Agency: A Permeable Legal Fiction For Tracing Culpability In Ai Systems, Anirban Mukherjee, Hannah H. Chang Jul 2026

Operational Agency: A Permeable Legal Fiction For Tracing Culpability In Ai Systems, Anirban Mukherjee, Hannah H. Chang

Research Collection Lee Kong Chian School Of Business

Modern artificial intelligence (AI) systems act with a high degree of independence yet lack legal personhood—a paradox that fractures doctrines grounded in human-centric notions of mens rea and actus reus. This Article introduces Operational Agency (OA)—a permeable legal fiction structured as an ex post evidentiary framework—and Operational Agency Graph (OAG)—a tool for mapping causal interactions among human actors, organizations, and AI systems. OA evaluates an AI’s observable operational characteristics: its goal-directedness (as a proxy for intent), predictive processing (as a proxy for foresight), and safety architecture (as a proxy for standard of care). OAG operationalizes that analysis by embedding these …


Sharksrx Newsletter Summer 2026, Nova Southeastern University Jul 2026

Sharksrx Newsletter Summer 2026, Nova Southeastern University

NSU Sharks Rx

No abstract provided.


Childhood Maltreatment Profiles And Premenstrual Dysphoric Disorder (Pmdd) Among Female Adolescents In Nigeria: A Latent Class Analysis, Wasiu Olorunlambe, Sherifat Adeniyi, Maricela Galdamez, Ruby Charak, Julian D. Ford Jul 2026

Childhood Maltreatment Profiles And Premenstrual Dysphoric Disorder (Pmdd) Among Female Adolescents In Nigeria: A Latent Class Analysis, Wasiu Olorunlambe, Sherifat Adeniyi, Maricela Galdamez, Ruby Charak, Julian D. Ford

Psychological Science Faculty Publications

Background

Premenstrual dysphoric disorders [PMDD] often emerge during adolescence and cause significant impairment to female adolescents. While studies have examined the relationship between child maltreatment [CM] and PMDD symptoms among women, studies with adolescents are scarce, particularly in Nigeria.

Objectives

The association between CM profiles and PMDD symptoms, depression and anxiety symptoms, suicidal ideation and social support was examined.

Participants and Settings

A school-based sample of 296 female adolescents [aged 10–22 years old] was enrolled in 11 local government areas within the Ibadan metropolis, Oyo State, Nigeria.

Methods

Self-report data from the Childhood Trauma Questionnaire [CTQ], Premenstrual Symptoms Screening Scale …


Ai-Powered Synthetic Biology: Current Situation, Challenges, And Future Perspectives, Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli Jul 2026

Ai-Powered Synthetic Biology: Current Situation, Challenges, And Future Perspectives, Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli

Research Outputs: 2025-Present

Synthetic biology has evolved from a set of engineering aspirations to an operationally sophisticated discipline, and artificial intelligence (AI) is its fastest-growing accelerant. This review traces that convergence across six interlocking domains: systems-level biological modeling, de novo protein engineering, metabolic and microbial programming, multi-omics data integration, regulatory element design, and clinical translation. For each domain, we survey established results, integrate findings from 2010–2026 literature, and articulate the trajectories that will define the next decade. Emerging themes include physics-informed neural networks for mechanistically constrained biological modeling, drug design, and federated learning architectures that allow global omics collaboration without centralizing sensitive data, …


Valorisation Potential Of Microalgae As A Sustainable Source Of Lipids And Health Promoting Compounds, Bozena Mccarthy Jul 2026

Valorisation Potential Of Microalgae As A Sustainable Source Of Lipids And Health Promoting Compounds, Bozena Mccarthy

Theses

The transition toward a circular bioeconomy requires sustainable strategies for managing and valorising food industry effluents while reducing reliance on environmentally damaging raw materials such as palm oil, which is associated with deforestation, biodiversity loss and greenhouse gas (GHGs) emissions. Microalgae represent a promising platform for converting nutrient rich industrial by-products into biomass and high-value compounds for food, nutraceutical and bio-based applications. Dairy processing generates large quantities of whey, creating environmental challenges due to its high organic load. Improved whey treatment and valorisation strategies are therefore essential for enhancing sustainability in food production systems. In this study, the biomass productivity …