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Durham Police Department Issues Missing Persons Notice For Alexis Garcia, Emma Kostyun

Digital Edition

An independent student produced newspaper from the University of New Hampshire.

“Medical Tent Scenes - Spectrum Of Musculoskeletal Injuries In Runners During A Distance Run In Coastal South India”, Santosh Pv Rai, Abhavya Jha, Ashish Prabhakar, Jeedhu Radhakrishna, Kausthubh Hegde

Manipal Journal of Medical Sciences

Problem Statement : Musculoskeletal injuries encountered by runners, especially during competitive sporting events like marathons and distance runs have a longstanding and significant impact on the well being and may result in a dip in the performance of the runners. They may be the cause of recurrent injuries in the future and can lead to complicated injuries, thus compounding the morbidity associated with initial injuries. In such cases, it is essential to allocate medical supplies and facilities based on the incidence of common injuries encountered by runners in the respective geographical and climate settings.

Approach : This cross sectional study …

Isolated Sphenochoanal Polyp – Case Report And Literature Review, Deviprasad Dosemane, Meera Niranjan Khadilkar, Nithya Chandy, Ravipati Rachana

Manipal Journal of Medical Sciences

Introduction - Choanal polyps are benign, solitary, hyperplastic lesions arising from the nasal or paranasal mucosa, most commonly from the maxillary sinus. They account for 3–6% of nasal polyps in adults and up to 33% in children, with sphenochoanal variants being rare. We report a case of a sphenochoanal polyp and review related literature to highlight this uncommon presentation.

Case report – A 17-year-old female presented with bilateral nasal obstruction, rhinorrhoea, and headache unresponsive to medication. DNE showed a glistening mass at the choana, and CT confirmed a sphenochoanal polyp arising from the sphenoid sinus. She underwent successful FESS with …

Soft Law, European Union

Documents

No abstract provided.

Multi-Scale Thermal Mapping Of Submarine Groundwater Discharge In Coastal Ecosystems Of A Volcanic Area, Ebony L. Williams, Christopher B. Kratt, Raymond S. Rodolfo, Mark R. Lapus, Ryan R. Lardizabal, Aya S. Bangun, Amber T. Nguyen, Scott W. Tyler, M. Bayani Cardenas

Environmental Science Faculty Publications

Submarine groundwater discharge (SGD) in volcanic areas commonly exhibits high temperatures, concentrations of metals and CO2, and acidity, all of which could affect sensitive coastal ecosystems. Identifying and quantifying volcanic SGD is crucial yet challenging because the SGD might be both discrete, through fractured volcanic rock, and diffuse. At a volcanic area in the Philippines, the novel combination of satellite and drone-based thermal infrared remote sensing, ground-based fiber-optic distributed temperature sensing, and in situ thermal profiling in coastal sediment identified the multi-scale nature of SGD and quantified fluxes. We identified SGD across ∼30 km of coastline. The different approaches revealed …

Capturing Creativity: An Exploration Of The Positive Impact Of Art Integration In Elementary Education, Christina Zander

Theses and Dissertations

My thesis focuses on the necessity of including art in education and the positive impact integrating art has on students mentally and academically. Over the past 2 years, I have seen the major impact integrating art has on students and how essential it is to keep creativity in the classroom. My research explains how incorporating art helps increase both student engagement and retention of concepts. I have also studied how integrating art with mindfulness can help students develop essential SEL skills including emotion management. My research expands on how utilizing art allows individuals and students to better cope with challenges …

Human-Bear Conflict In North America (1880-2020): A Comprehensive Analysis Of Patterns, Outcomes And Interactions, Cody Robert Miller

Theses and Dissertations

Human-bear (Ursus spp.) conflict (HBC) is an important issue facing wildlife managers across North America. It is essential that we understand the factors associated with HBCs in North America so that wildlife managers can make appropriate, science-based recommendations about how to avoid, and if necessary, survive such incidents. To that end, we present this comprehensive analysis of > 2,100 HBCs in the United States and Canada, ranging from 1880 to the present. This analysis includes the three native North American bear species: black bears (Ursus americanus), grizzly bears (U. arctos), and polar bears (U. maritimus) and assesses the role that twelve …

Accelerated Historical And Future Warming In The Middle East And North Africa, Abdul Malik, Georgiy Stenchikov, Suleiman Mostamandi, Sagar Parajuli, Jos Lelieveld, George Zittis, Muhammad Sheraz Ahsan, Luqman Atique, Muhammad Usman

All Works

The present study assesses the climate of the Middle East and North Africa (MENA) in detail, focusing on the historical and future warming trends in the region. The assessment incorporates data from observations, reanalyses, and statistically downscaled climate models from the Coupled Model Intercomparison Project Phases 5 and 6. Since the pre-industrial era, the observed average climate in the MENA has warmed by 1.5°C and is on the brink of exceeding 2°C. The reanalysis data suggest that the regional warming over some MENA sub-regions is three times faster than the global average. By the end of the 21st century, the …

Addressing Grand Challenges Through The Bottom-Up Marketing Approach: Lessons From Subsistence Marketplaces And Marketplace Literacy, Madhubalan Viswanathan, Arun Sreekumar, Srinivas Sridharan, Gaurav R. Sinha

Marketing & Business Law Faculty Works

We present a bottom-up marketing approach as a pathway to addressing the grand challenge of poverty and inequality for the marketing discipline. We derive this approach from the research stream on radically different contexts of subsistence marketplaces. Research on subsistence marketplaces has typically explored micro-level phenomena but also traversed upward and explained aggregate phenomena at higher levels. We present a conceptual framework to encapsulate general and granular elements of the bottom-up marketing approach. Study 1 demonstrates general elements of the framework through a retrospective examination of the global diffusion of a marketplace literacy program. Study 2 demonstrates the more granular …

The Dual Timescales Of Gait Adaptation: Initial Stability Adjustments Followed By Subsequent Energetic Cost Adjustments, Sasha A. Brinkerhoff, Natalia Sánchez, Meral N. Culver, William M. Murrah, Austin T. Robinson, J. Danielle Mccullough, Matthew W. Miller, Jaimie A. Roper

Physical Therapy Faculty Articles and Research

Gait adaptation during bipedal walking allows people to adjust their walking patterns to maintain balance, avoid obstacles and avoid injury. Adaptation involves complex processes that function to maintain stability and reduce energy expenditure. However, the processes that influence walking patterns during different points in the adaptation period remain to be investigated. We assessed split-belt adaptation in 17 young adults aged 19–35. We also assessed individual aerobic capacity to understand how aerobic capacity influences adaptation. We analyzed step lengths, step length asymmetry (SLA), mediolateral margins of stability, positive, negative and net mechanical work rates, as well as metabolic rate during adaptation. …

A Virtual Scalable Model Of The Hepatic Lobule For Acetaminophen Hepatotoxicity Prediction, Stelian Camara Dit Pinto, Jalal Cherkaoui, Debarshi Ghosh, Valentine Cazaubon, Kenza E Benzeroual, Steven M Levine, Mohammed Cherkaoui, Gagan K Sood, Sharmila Anandasabapathy, Sadhna Dhingra, John M Vierling, Nicolas R Gallo

Faculty, Staff and Students Publications

Addressing drug-induced liver injury is crucial in drug development, often causing Phase III trial failures and market withdrawals. Traditional animal models fail to predict human liver toxicity accurately. Virtual twins of human organs present a promising solution. We introduce the Virtual Hepatic Lobule, a foundational element of the Living Liver, a multi-scale liver virtual twin. This model integrates blood flow dynamics and an acetaminophen-induced injury model to predict hepatocyte injury patterns specific to patients. By incorporating metabolic zonation, our predictions align with clinical zonal hepatotoxicity observations. This methodology advances the development of a human liver virtual twin, aiding in the …

Munchausen Syndrome By Proxy Presentation, Giovanna Tomassoni, Meredith Mackenzie

Master's Projects

Munchausen syndrome by proxy (MSBP) is a serious form of child abuse in which the perpetrator is typically the victim’s maternal caregiver. Assessing for MSBP can be very challenging for medical providers due to symptom mimicry and a dearth of information about the disorder. This Integrative Review seeks to shine a light on common symptomatology of MSBP and to make sure that providers leave it on the differential diagnosis until alternative diagnoses can effectively exclude it. A total of 240 records from online databases were reviewing for content, currency, and rigor. This search was narrowed to 10 records for in-depth …

Association Of Acute Rejection And De Novo Renal Cell Carcinoma In Kidney Transplant Patients: An Optn Data Analysis, Molly Casey, Emmalie Yanacek, Hitesh Kaul, John Knorr, Kamran Khanmoradi, Afshin Parsikia, Nikolaos Chandolias, Kevin Zarrabi, Radi Zaki

Einstein Health Papers

Background: Kidney Transplant Recipients (KTRs) are at risk of renal cell carcinoma (RCC). The risk of RCC in KTRs is approximated to be 5–10 times higher compared with the general population. A relation between kidney rejection and renal malignancy has been described and relates to the effect of immunosuppression at the genomic level. We decided to investigate any suggestive clinical evidence of this in the OPTN database. Methods: KTRs with de novo RCC between July 2004 and June 2022 were identified. Demographics, baseline characteristics, virology, and immunology data were compared between patients with and without RCC. Our follow-up period was …

Recognition Or Refusal? Marginalized Identity Development In Passing And The Color Purple, Lee Kassay

Longwood Senior Theses

No abstract provided.

Effective Nutrient Management Of Surface Waters In The United States Requires Expanded Water Quality Monitoring In Agriculturally Intensive Areas, Christopher Oates, Hactor Fajardo, Khara Grieger, Daniel Obenaur, Rebecca Muenich, Natalie G. Nelson

Biological and Agricultural Engineering Faculty Publications and Presentations

The U.S. Clean Water Act is believed to have driven widespread decreases in pollutants from point sources and developed areas, but has not substantially affected nutrient pollution from agriculture. Today, the highest nutrient concentrations in surface waters are often associated with agricultural production. In this Perspective, we explore whether challenges stemming from the Clean Water Act’s inability to mitigate agricultural nutrient pollution are also exacerbated by coarse nutrient monitoring. We evaluate the current state of nutrient monitoring in surface waters of the contiguous U.S. relative to agricultural nutrient inputs to assess how monitoring effort varies across agriculturally intensive areas. The …

Context, Mechanisms And Community Engagement In Implementation Strategies: A Systematic Review Protocol Of Implementation Strategies Designed Using Implementation Mapping, Eunyoung Kang, Gill Ten Hoor, Derek W Craig, Serena Rodriguez, Jennifer Stockton, Maria E Fernandez

Faculty, Staff and Student Publications

INTRODUCTION: Implementation Mapping (IM) has increasingly been used for the design and/or selection and tailoring implementation strategies to promote the effective translation of evidence-based interventions into practice. IM is a tool for guiding the systematic, iterative, step-by-step design process that helps guide the co-creation of theory-based, evidence-informed implementation strategies. This protocol aims to describe the methods of the planned systematic review that will (1) examine the overall landscape of IM in developing implementation strategies, (2) explore the mechanisms of implementation strategies developed using IM and (3) investigate the use of IM and community engagement in the development of implementation strategies. …

Complement Immune System In Pulmonary Hypertension-Cooperating Roles Of Circadian Rhythmicity In Complement-Mediated Vascular Pathology, Hunter Devaughn, Haydn E Rich, Anthony Shadid, Priyanka K Vaidya, Marie-Francoise Doursout, Pooja Shivshankar

The Brown Foundation: Institute of Molecular Medicine

Originally discovered in the 1890s, the complement system has traditionally been viewed as a "compliment" to the body's innate and adaptive immune response. However, emerging data have shown that the complement system is a much more complex mechanism within the body involved in regulating inflammation, gene transcription, attraction of macrophages, and many more processes. Sustained complement activation contributes to autoimmunity and chronic inflammation. Pulmonary hypertension is a disease with a poor prognosis and an average life expectancy of 2-3 years that leads to vascular remodeling of the pulmonary arteries; the pulmonary arteries are essential to host homeostasis, as they divert …

Severity Of Symptoms As An Independent Predictor Of Poor Outcomes In Patients With Advanced Cancer Presenting To The Emergency Department: Secondary Analysis Of A Prospective Randomized Study, Aiham Qdaisat, Elizabeth Stroh, Cielito Reyes-Gibby, Monica K Wattana, Jayne Viets-Upchurch, Ziyi Li, Valda D Page, Huda Fatima, Patrick Chaftari, Ahmed Elsayem

Faculty, Staff and Student Publications

Background/Objectives: Patients with advanced cancer often present to the emergency department (ED) with pain and distressing symptoms that are not systematically evaluated. The current study investigated the association of symptom severity with the diagnosis of delirium and short-term survival.

Methods: In this secondary analysis of a prospective randomized study of delirium among advanced cancer patients in the ED, in which symptoms were assessed by the MD Anderson Symptom Inventory (MDASI), we analyzed the distribution of MDASI item scores by 90-day mortality (Kolmogorov-Smirnov), the association of MDASI item scores with short-term mortality (logistic regression models), and the symptoms in …

An Exploration Of Texas Latinos’ Perceptions Of Law Enforcement And Undocumented Immigration In The United States, Marika Dawkins-Cavazos, Camille Gibson

Criminal Justice Faculty Publications

Given increased trepidation about undocumented immigration in the United States, this study offers an examination of the extent to which Latinos who represent different generations of immigrants perceive United States law enforcement and the current state of undocumented immigration. It gives voice to Latinos, the most significant demographic crossing the border. The topic is relevant given policymakers’ interest in addressing the moral panic over increasing immigration to the country and an interest in law enforcement legitimacy as an essential ingredient in their effectiveness in combating crimes. This qualitative study using semi-structured interviews describes the perceptions of 40 Texas Latinos regarding …

Author Spotlight, Li-Fang Yang, Joseph W. Sampson, Xiao-Hang Sun, Hai-Qiang Deng, He Zhang, Md Maksudur Rahman, Yang Tao, Hang Ren

Journal of Electrochemistry

No abstract provided.

Preface To Special Issue On Single-Entity Electroanalysis, Fei Li, Yi-Lun Ying, Yi-Ge Zhou

Journal of Electrochemistry

No abstract provided.

Single-Entity Collisional Electrochemistry At The Micro- And/Or Nano-Interface Between Two Immiscible Electrolyte Solutions, Li-Fang Yang, Jun-Jie Chen, Ling-Yu Chen, Si-Qi Jin, Tao-Xiong Fang, Si-Jia He, Liang-Jun Shen, Xin-Jian Huang, Xiao-Hang Sun, Hai-Qiang Deng

Journal of Electrochemistry

Single-entity collisional electrochemistry (SECE) is a branch of single-entity electrochemistry. It can directly characterize entities/particles with single particle resolution through random collisions between particles and electrodes in a solution, and obtain rich physicochemical information, thus becoming one of the frontiers of electroanalytical chemistry in the past two decades. Interestingly, the (micro/nanoscale) sensing electrodes have evolved from a polarizable liquid/ liquid (mercury/liquid) interface to a solid/liquid interface and then to a liquid/liquid interface (i.e., an interface between two immiscible electrolyte solutions, ITIES), as if they have completed a cycle (but in fact they have not). ITIES has become the latest sensing …

Precision Delivery Using Nanopipette For Single-Cell Studies, He Zhang, Maksudur Rahman, Yang Tao, Joseph W Sampson, Hang Ren

Journal of Electrochemistry

Nanopipette based scanning probe technique is a versatile tool in non-contact imaging in biology. In addition to the topographic imaging, its capability of localized delivery of bio-active molecules is emerging. In this mini review, we introduce the applications of nanopipette in single-cell researches with a focus on localized delivery. The working principles of three delivery modes including resistive pulse, pressure-driven flow, and electroosmotic flow-driven delivery are summarized and compared. Their applications in single-cell researches are reviewed. The current technical challenges in scanning ion conductance microscopy-based delivery, and their growing influence in medicine and pharmacologic researches are also discussed.

Aqueous Supercapacitors With Wide Operative Voltage Window And Long Cycling Life Enabled By Electrolyte Hybridization Effect, Shi-Hua Ma, Qi Yin, Jin-Ping Zhao

Journal of Electrochemistry

Developing supercapacitors (SCs) with long cycling life and wide operative voltage window is a significant topic in the field of aqueous electrolytes. Although the design of water in salt (WIS) electrolytes has pushed the development of aqueous electrolytes to a new height, the WIS electrolytes with an operative voltage window of up to 2.5 V is still very scarce. Herein, in order to enrich the type of aqueous electrolyte with high operative voltage, tetramethylammonium trifluoromethanesulfonate (TMAOTf) based WIS electrolyte was used as a model to construct WIS based hybrid electrolyte with acetonitrile (ACN) co-solvent and LiTFSI co-solute. In view of …

Journal Of Electrochemistry, The Flagship Journal Of Chinese Chemical Society Electrochemical Committee, Made A Public Appearance At The 22nd National Electrochemical Congress, Editorial Office Of J.Electrochem.

Journal of Electrochemistry

No abstract provided.

The Award Ceremony Of The 2nd Xiamen University Short Video Abstract Contest For Science And Technology Journal Papers Came To A Successful Conclusion, Editorial Office Of J.Electrochem.

Journal of Electrochemistry

No abstract provided.

The 9th National Conference Of Solid State Battery Successfully Held In Xiamen, Fujian, Zheng-Liang Gong

Journal of Electrochemistry

No abstract provided.

Focal Deletions Of A Promoter Tether Activate The Irx3 Oncogene In T-Cell Acute Lymphoblastic Leukemia, Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R Costa, David O'Connor, Rachael Pocock, Tanya Rapoz-D'Silva, Adam Turna, Lingyi Wang, Soowah Lee, Adele K Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R Hughes, James O J Davies, Alejandro Gutierrez, Michelle A Kelliher, Peter Van Loo, Mark A Dawson, Marc R Mansour

Faculty, Staff and Student Publications

Oncogenes can be activated in cis through multiple mechanisms including enhancer hijacking events and noncoding mutations that create enhancers or promoters de novo. These paradigms have helped parse somatic variation of noncoding cancer genomes, thereby providing a rationale to identify noncanonical mechanisms of gene activation. Here we describe a novel mechanism of oncogene activation whereby focal copy number loss of an intronic element within the FTO gene leads to aberrant expression of IRX3, an oncogene in T-cell acute lymphoblastic leukemia (T-ALL). Loss of this CTCF-bound element downstream to IRX3 (+224 kb) leads to enhancer hijack of an upstream developmentally active …

The Pharmacogenomic And Immune Landscape Of Snornas In Human Cancers, Runhao Wang, Chengxuan Chen, Yuan Liu, Mei Luo, Jingwen Yang, Yamei Chen, Lifei Ma, Liuqing Yang, Chunru Lin, Lixia Diao, Leng Han

Faculty, Staff and Student Publications

Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs primarily known for their role in the chemical modification of other RNAs. Recent studies suggested that snoRNAs may play a broader role in anti-cancer treatments such as targeted therapies and immunotherapies. Despite these insights, the comprehensive landscape of snoRNA associations with drug response and immunotherapy outcomes remains unexplored. In this study, we identified 79,448 and 75,185 associations between snoRNAs and drug response using data from VAEN and CancerRxTissue, respectively. Additionally, we discovered 29,199 associations between snoRNAs and immune checkpoint genes and 47,194 associations between snoRNAs and immune cell infiltrations. Sixteen …

Blood Matters: The Hematological Signatures Of Coronavirus Infection, Ayelen Toro, Ana P Arévalo, Marianoel Pereira-Gómez, Agustina Sabater, Eric A Zizzi, Paula Perbolianachis, Gaston Pascual, Sofia Lage-Vickers, Jorge L Pórfido, Ines Achinelli, Rocio Seniuk, Juan Bizzotto, Pablo Sanchis, Alvaro Olivera, Alejandro Leyva, Pilar Moreno, Alicia Costábile, Alvaro Fajardo, Federico Carrión, Martín Fló, Natalia Olivero-Deibe, Fernando Rodriguez, Nicolas Nin, Nicolas Anselmino, Estefania Labanca, Elba Vazquez, Javier Cotignola, Daniel F Alonso, Maria P Valacco, Marcelo Marti, Francesco Gentile, Artem Cherkasov, Martina Crispo, Gonzalo Moratorio, Geraldine Gueron

Faculty, Staff and Student Publications

Recent developments have broadened our perception of SARS-CoV-2, indicating its capability to affect the body systemically beyond its initial recognition as a mere respiratory pathogen. However, the pathways of its widespread are not well understood. Employing a dual-modality approach, we integrated findings from a Murine Hepatitis Virus (MHV) infection model with corroborative clinical data to investigate the pervasive reach of Coronaviruses. The novel presence of viral particles within red blood cells (RBCs) was demonstrated via high-resolution transmission electron microscopy, with computational modeling elucidating a potential heme-mediated viral entry mechanism via Spike protein affinity. Our data affirm viral localization in RBCs, …