Digital Commons Network^™

Paloob At Palabas Ng Ateneo Entablado: Pag-Uugat Ng Ateneo Entabladosa Tradisyong Pantanghalan At Sosyo-Politikal Ng Ateneo De Manila, Jerome D. Ignacio

Katipunan

Ang Ateneo ENTABLADO ay isa sa tatlong pangkat panteatro ng Pamantasang Ateneo de Manila. Tinatangi ng ENTABLADO ang sarili sa pamamagitan ng pagpapakilala sa sarili nito bilang sosyo-politikal na pangkat panteatro. Nais siyasatin ng pag-aaral kung paano umusbong at sumulong ang isang sosyo-politikal na pangkat panteatro sa loob ng isang paaralang eksklusibo. Nilalayon ng pag-aaral samakatwid na taluntunin ang tradisyong pantanghalan at sosyo-politikal ng Ateneo ENTABLADO. Iuugat ito ng pag-aaral sa mayamang tradisyong pantanghalan at sosyo-politikal ng mismong institusyong kinabibilangan nito, ang Pamantasang Ateneo de Manila. Gagamitin ng pag-aaral bilang konseptuwal na balangkas ang diskurso ng (pa)loob at (pa)labas upang …

Ang Retorika Ng Satira Ni Juana Change: Agresyon At Panliligalig, John Carlo S. Gloria

Katipunan

Mabulas na sandata ang satira na may mahaba nang kasaysayan ng pagbibigay-kritika sa kapangyarihan, paglalantad ng mga kontradiksiyon, at pag-uudyok sa isipan gamit ang pamumuna at pagpapatawa. Magkagayunman, dapat ding mabanggit na bahagi ng kasaysayang ito ang pagsasailalim ng satira sa iba pang anyo. Bunga ng kadalian nitong maiangkop sa ibang genre, lumabnaw ang mga pagsasakatangian sa satira at waring nanatiling nakahimpil ito sa anino ng mga anyong higit na bago kung ihahambing dito. Buhat sa ganitong pangangatwiran, lumilitaw ang pangangailangang muling turulin ang mga katangian ng satira na nagpapatampok dito. Pinoproblematisa ng sanaysay samakatwid ang pagkanatatangi ng satira bilang …

Angiography And Embolization Procedures To Minimize Complications In Melanotic Neuroectodermal Of Infancy (Mnti) Management Of Pediatric: A Rare Case, Mb. Lutfianto, Septa Hera W., Edwyn Saleh

Journal of Dentomaxillofacial Science

Background:melanotic neuroectodermal of infancy (MNTI) is a very rare benign pigmented neoplasm originating from the neural crest associated with increased excretion of vanillylmandelic acid. Fewer than 500 cases have been reported to date. Usually painless, often based on an epithelial surface, blue to black in color with extensive and aggressive growth. MNTI vascularization is rarely reported, requiring MRI radiographic examination, angiography, embolization and biopsy to support diagnosis and surgical management as well as minimizing complications.

Case report: a 2 year old male brought by his parents to the Oral Surgery clinic at Dr. Sardjito Hospital complained that the lump …

Roger Williams University 2024 President's Report: A Message From President Miaoulis, Roger Williams University

Life of the Law School (1993- )

No abstract provided.

57(3) Front Matter

UBC Law Review

No abstract provided.

Miscarriages Of Justice In Immigration Detention, Louis Century, Kent Roach

UBC Law Review

No abstract provided.

Municipal Constitutionalism And Its Origins, James Collie

UBC Law Review

No abstract provided.

Search Incident To Arrest And The Role Of Law Enforcement Interests, Colton Fehr

UBC Law Review

No abstract provided.

The Cost Of Honest Contract Performance, Michael Ilg

UBC Law Review

No abstract provided.

Scoring Campus Sexual Violence Policies Across Canada: A Comparative Policy And Criminal Approach, Caitlin Salvino

UBC Law Review

No abstract provided.

So, I Guess We’Re Going With Vacuous Political Bromide: A Commentary On Gitxaala V British Columbia (Chief Gold Commissioner), 2023 Bcsc 1680, Jeffrey Warnock

UBC Law Review

No abstract provided.

Assessing The Influence Of Native And Invasive Grasses On The Behavior Of Aedes Aegypti In South Texas, Emily Medelez

Theses and Dissertations

Invasive grasses in South Texas can have widespread negative effects, displacing native species, reducing biodiversity, and posing risks to public health. These grasses may flourish in moist, shaded environments, which not only support their growth but also creates habitats favorable for mosquito activity. This can increase the population and alter the behavior of mosquitoes, potentially raising the risk of disease transmission. In this thesis, I look at the behavior of mosquito species Aedes aegypti, primary vector of the yellow fever virus. I analyzed the influence of oviposition, flight and resting behaviors. I tested the relative attraction of Aedes mosquitoes …

Microwave-Assisted Green Synthesis Of Spiroindolinopyranopyrazoles, Esther Owusu

Theses and Dissertations

Green Chemistry, usually known as sustainable chemistry, is widely implemented worldwide to safeguard human health and the environment. Recent investigations in organic synthesis and chemical transformation have demonstrated that green chemistry techniques are significantly reducing both chemical waste and reaction time. In order to fulfill this ecological requirement, it is crucial to lessen the utilization of perilous solvents and noxious chemicals, while also creating innovative reaction methods that decrease the production of trash. The implementation of such methodologies can greatly enhance the field of green chemistry. A more environmentally friendly synthetic method was utilized to generate spiro chemicals and their …

Policies And Price Controls On The Research And Development Of Orphan Drugs In The United States And The European Union, Bena Pearl Filipczak Smith

Master's Theses

There is substantive literature surrounding the impact of price controls on the research and development (R&D) of new pharmaceutical products. The European Union (EU) and United States (US) are often studied in contrast to examine the influence of price controls as the US has fewer pharmaceutical price controls than the EU.

We find moderate evidence that the US spent more on annual domestic pharmaceutical R&D than the EU between 2004 and 2021, on average, before and after adjusting for GDP growth per capita and year. We find strong evidence that the US increased annual domestic R&D spending at a faster …

Using The Intercultural Development Inventory To Measure Intercultural Development For A High-Impact Global Community Engagement Program, Jennifer Crystle, Megan W. Moran, Diana G. Venskus

Journal of Global Education and Research

High-impact practices (HIPs) in higher education, such as global community engagement programs, enhance student learning and lead to increased levels of civic involvement among graduates. However, it is unknown if participation in a global community engagement/service-learning program affects the development of cultural competence. The purpose of this study was to determine if student and faculty participation in a two-week community engagement/service-learning program in Guatemala would result in intercultural development measured using the Intercultural Development Inventory (IDI) tool. Participants were recruited from a graduate physical therapy education program in the U.S. and completed a pre- and post-trip IDI. Data analysis revealed …

Using High-Pressure Processing To Improve The Quality Of Dark-Cutting Beef, Ashley A. Hahn

Department of Animal Science: Dissertations, Theses, and Student Research

Previous studies have shown high-pressure processing (HPP) can be utilized to improve lean color of dark-cutting beef color by increasing the lightness and redness of steaks. However, the optimal parameters of length of time product is held under pressure and at which pressure must be applied have yet to be fully defined. Furthermore, the impact of HPP on color labile muscles in dark-cutting beef are currently unknown. Therefore, two studies were designed and specific efforts were focused on first defining optimal parameters for color stable muscles, followed by determining the effect of HPP on dark-cutting color labile muscles.

In the …

Relationship Between Host Genomics And Microbiomics In Beef Cattle, Andrew D. Lakamp

Department of Animal Science: Dissertations, Theses, and Student Research

As sequencing technology becomes more affordable and throughput increases, microbiome information is becoming more readily available. For beef cattle selection, microbial information has a variety of uses including being a target for genetic prediction or used as a means to explicitly describe additional phenotypic variability in other traits.

Infectious bovine keratoconjunctivitis (IBK), commonly known as pinkeye, is a disease that infects the ocular surface and surrounding tissue which is an animal health and producer economic concern. Vaccinations have shown to have variable effectiveness, while limited genetics studies have suggested that direct genetic selection for resistance would be slow. Therefore, an …

Examining Factors Of Variance In Energy Metabolism Of Dairy Cattle, Addison L. Carroll

Department of Animal Science: Dissertations, Theses, and Student Research

Variation is thought to occur in the use of dietary energy for production in dairy cattle. First, variance can be observed when new methane mitigation strategies are fed resulting in increased H₂ output potentially resulting in downstream effects on estimates of heat production via the Brouwer (1965) equation. Therefore, in chapter 3 a review was created to systematically describe the mathematics and theory behind the Brouwer equation, and rederive a heat production equation to integrate H₂ production. Results indicate heat production using the classical Brouwer equation (1965) relative to the rederived equation resulted in an overestimation of heat …

Impacts Of Annual Forage Management On Grazing Cattle Performance And Carrying Capacity, Shelby Davies Jenkins

Department of Animal Science: Dissertations, Theses, and Student Research

Rapid conversion of historical grasslands to cropland in recent history has led to limited perennial pasture availability and an increase in cost of pasture rent. Annual forages are an alternative grazing source. Many annual forages can grow and accumulate stockpile following summer harvest of wheat. Strip grazing is often suggested to increase grazing efficiency of stockpiled forages. To evaluate this, a stockpiled mixture of annual forages were either strip grazed or grazed continuously in the fall and winter. The mixture contained oats and rapeseed in the first year and a diverse warm season annual mixture in the second. Strip grazing …

Exploring The Teaching Of Reading In Lower Primary Classes: A Case Study Of One Government Primary School In Kocheka Sub County, Uganda, Nipael Mrutu, Kulwenza Rachael

Institute for Educational Development, East Africa

Purpose: The purposeof this study was to investigates the methods teachers use to teach reading in lower primary classes at a government primary school in Kocheka Sub County, Uganda, focusing particularly on how these methods impact learners' reading competences.

Methodology: Aqualitative case study approach was utilized, employing interviews and document analysis to gather data from six teachers, one head teacher, and one District Inspector of Schools (DIS).

Findings: The findingshighlight the use of phonics, whole language, and balanced methods. Further, they reveal that teachers are conversant with these methods and understand how they affect learners’ reading skills. The DIS noted …

Analysis Of Bck/Bci-Algebras Based On Bipolar Complex Intuitionistic Fuzzy Soft Ideals, Zeeshan Ali

Neutrosophic Systems with Applications

In this article, we design an informative and reliable technique of bipolar complex intuitionistic fuzzy soft sets with numerous operational laws by merging the model of soft sets, complex fuzzy sets, and bipolar intuitionistic fuzzy sets to handle imprecise data. In addition, an ideal in a BCK-algebra is derived based on bipolar complex intuitionistic fuzzy soft set theory are proposed which can capture the information of hesitancy, vagueness, and non-membership information within the circumstance of BCK-algebra. Moreover, we design union, intersection, AND, and OR based on bipolar complex intuitionistic fuzzy soft ideal and simplify it with the help of numerous …

Whole Exome-Seq And Rna-Seq Data Reveal Unique Neoantigen Profiles In Kenyan Breast Cancer Patients, Godfrey Wagutu, John Gitau, Kennedy Mwangi, Mary Murithi, Elias Melly, Alexandra R. Harris, Shahin Sayed, Stefan Ambs, Francis Makokha

Pathology, East Africa

Background: The immune response against tumors relies on distinguishing between self and non-self, the basis of cancer immunotherapy. Neoantigens from somatic mutations are central to many immunotherapeutic strategies and understanding their landscape in breast cancer is crucial for targeted interventions. We aimed to profile neoantigens in Kenyan breast cancer patients using genomic DNA and total RNA from paired tumor and adjacent non-cancerous tissue samples of 23 patients.

Methods: We sequenced the genome-wide exome (WES) and RNA, from which somatic mutations were identified and their expression quantified, respectively. Neoantigen prediction focused on human leukocyte antigens (HLA) crucial to cancer, HLA type …

Development Of Novel Ionization Chambers For Reference Dosimetry In Electron Flash Radiotherapy, Kevin Liu, Shannon Holmes, Ahtesham Ullah Khan, Brian Hooten, Larry Dewerd, Emil Schüler, Sam Beddar

Faculty, Staff and Student Publications

Background: Reference dosimetry in ultra-high dose rate (UHDR) beamlines is significantly hindered by limitations in conventional ionization chamber design. In particular, conventional chambers suffer from severe charge collection efficiency (CCE) degradation in high dose per pulse (DPP) beams.

Purpose: The aim of this study was to optimize the design and performance of parallel plate ion chambers for use in UHDR dosimetry applications, and evaluate their potential as reference class chambers for calibration purposes. Three chamber designs were produced to determine the influence of the ion chamber response on electrode separation, field strength, and collection volume on the ion chamber response …

Pathway-Based Clustering Identifies Two Subtypes Of Cancer-Associated Fibroblasts Associated With Distinct Molecular And Clinical Features In Pancreatic Ductal Carcinoma, Hongjing Ai, Rongfang Nie, Xiaosheng Wang

Faculty, Staff and Student Publications

Existing single-cell clustering methods are based on gene expressions that are susceptible to dropout events in single-cell RNA sequencing (scRNA-seq) data. To overcome this limitation, we proposed a pathway-based clustering method for single cells (scPathClus). scPathClus first transforms single-cell gene expression matrix into pathway enrichment matrix and generates its latent feature matrix. Based on the latent feature matrix, scPathClus clusters single cells using the method of community detection. Applying scPathClus to PDAC scRNA-seq datasets, we identified two types of cancer-associated fibroblasts (CAFs), termed csCAFs and gapCAFs, which highly expressed complement system and gap junction-related pathways, respectively. Spatial transcriptome analysis revealed …

Association Of Late Eating With Colorectal Adenomas: A Cross-Sectional Study, Darbaz Adnan, Edena R Khoshaba, Mostafa Abel-Reheem, Jonathan Q Trinh, Yin Cao, Faraz Bishehsari

Faculty, Staff and Student Publications

Purpose: Colorectal cancer (CRC) is linked to lifestyle exposures. However, changes in the CRC rates among younger populations remain poorly understood and suggest the existence of yet unidentified factor(s) that may contribute to colon carcinogenesis. Here, we investigated the potential role of time of eating in the risk of pre-cancerous colonic neoplasms (tubular adenoma: TA).

Methods: We enrolled 663 participants undergoing screening colonoscopies. Data on food timing, dietary intake, sleep/wake patterns, and chronotype were collected through structured questionnaires. Late eating was defined as the consumption of food or snack within a 3-hour window of sleep onset for at least four …

Why And When Do We Invasively Restage After Neoadjuvant Chemoimmunotherapy?, Jonathan D Spicer, Tina Cascone, Murry W Wynes, Karen L Kelly

Faculty, Staff and Student Publications

No abstract provided.

Mimicking Large Spot-Scanning Radiation Fields For Proton Flash Preclinical Studies With A Robotic Motion Platform, Fada Guan, Dadi Jiang, Xiaochun Wang, Ming Yang, Kiminori Iga, Yuting Li, Lawrence Bronk, Julianna Bronk, Liang Wang, Youming Guo, Narayan Sahoo, David R Grosshans, Albert C Koong, Xiaorong R Zhu, Radhe Mohan

Faculty, Staff and Student Publications

Previously, a synchrotron-based horizontal proton beamline (87.2 MeV) was successfully commissioned to deliver radiation doses in FLASH and conventional dose rate modes to small fields and volumes. In this study, we developed a strategy to increase the effective radiation field size using a custom robotic motion platform to automatically shift the positions of biological samples. The beam was first broadened with a thin tungsten scatterer and shaped by customized brass collimators for irradiating cell/organoid cultures in 96-well plates (a 7-mm-diameter circle) or for irradiating mice (1-cm

The Fletcher-Cox Pathway: A Unique View On Clinical Trial Education, Shalini Moningi, Shane Stecklein, Sonal Noticewala, Olsi Gjyshi, Todd Pezzi, David Boyce-Fappiano, Prajnan Das, Bruce Minsky, Emma B Holliday, Andrew J Bishop, Albert C Koong, Chelsea C Pinnix

Faculty, Staff and Student Publications

Purpose: There currently are no established formal mentorship and training programs for radiation oncology (RO) trainees to learn trial design, creation, writing, or implementation. There only exists informal training on analyzing clinical trials in RO residency programs. The integration of a longitudinal formal training and mentorship program for clinical trialists-consisting of clinical trial education, design, mentorship, and implementation during the RO residency education-will give residents not only formal teaching in the subject but also strong tools and requisite mentorship in hopes to help them succeed as future academic physicians and leaders in the field of RO.

Methods and materials: We …

Evaluating Pre-Consult Patient Education Videos For Patients With Newly-Diagnosed Anal Squamous Cell Carcinoma: Impact On Patient Comprehension, Satisfaction And Distress, Kelsey L Corrigan, Lauren M Andring, Prajnan Das, Cheryl Pfennig, Kimberly B Porter, Ethan B Ludmir, Sonal S Noticewala, Bruce D Minsky, Grace L Smith, Eugene J Koay, Albert C Koong, Angelica Arzola, Sarah J Lee, Lashon Nelms, Emma B Holliday

Faculty, Staff and Student Publications

We hypothesized that pre-consult patient education videos can improve patient understanding about their diagnosis, lead to high satisfaction and low distress. In this pilot study, we developed a patient education video curriculum for patients with newly-diagnosed anal cancer. Comprehension of key content was evaluated by comparing pre- and post-test scores. Patient satisfaction scores were collected. Patient distress scores (0-10) were collected at the beginning of their consult visit prior to seeing the physician. We found that patient education videos prior to consult improved patient understanding, resulted in high patient satisfaction, and low patient distress at the time of consult.

High Activity Of The New Myeloablative Regimen Of Gemcitabine/Clofarabine/Busulfan For Allogeneic Transplant For Aggressive Lymphomas, Jeremy Ramdial, Ruitao Lin, Peter F Thall, Benigno C Valdez, Chitra Hosing, Samer Srour, Uday Popat, Muzaffar Qazilbash, Amin Alousi, Melissa Barnett, Alison Gulbis, Terri Lynn Shigle, Elizabeth J Shpall, Borje S Andersson, Yago Nieto

Faculty, Staff and Student Publications

Refractory aggressive lymphomas can be treated with allo-SCT, pursuing a graft-vs-lymphoma effect. While reduced intensity conditioning is safe, tumors often progress rapidly, indicating the need for more active conditioning regimens. The preclinical synergy we saw between gemcitabine (Gem), clofarabine (Clo) and busulfan (Bu) against lymphoma cell lines led us to study Gem/Clo/Bu clinically. Eligibility: age 12-65, refractory aggressive B-NHL, T-NHL or Hodgkin, with a matched donor. Infusional Gem was dose-escalated on days (d) -6 and -4 (475-975 mg/m2/day), followed by Clo (40 mg/m2/day) and Bu (target AUC, 4000 μMol min/day) (d -6 to -3). CD20+ tumors received rituximab. GVHD prophylaxis …