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Predicting (And Protecting) The Future Of Environmental Law After Loper Bright, Sanne H. Knudsen Dec 2024

Predicting (And Protecting) The Future Of Environmental Law After Loper Bright, Sanne H. Knudsen

Articles

Nostradamus, the sixteenth-century French philosopher and seer, is said to have predicted many things: the French Revolution, the rise of Napoleon, the Great Fire of London, the rise of Adolf Hitler, the 9/11 attacks on the World Trade Center. Of course, there are skeptics. The predictions, after all, tended to be “cryptic and vague.”

Still, if alive today, I wonder what quatrain Nostradamus might write—and what elusive meaning his fans might try to decode—about the future of environmental law in the United States. Would he predict that environmental law will be ravaged by the binary politics of the moment, reduced …


Disability Discrimination By Clinical Algorithm, Elizabeth Pendo, Jennifer D. Oliva Dec 2024

Disability Discrimination By Clinical Algorithm, Elizabeth Pendo, Jennifer D. Oliva

Articles

In response to America’s escalating drug poisoning crisis, the federal government has funded, incentivized, and mandated that states adopt and implement prescription drug monitoring programs (“PDMPs”) to electronically surveil controlled substances and other “drugs of concern.” State PDMPs utilize proprietary, predictive software platforms that deploy algorithms to determine whether a patient is at risk for drug misuse, drug diversion, doctor shopping, or substance use disorder. PDMPs have never been validated by a federal agency or peer review, yet states have mandated their use throughout the health care delivery system.

Research demonstrates that clinical overreliance on the risk scores generated by …


Directional Web Strikes Performed By Ray Spiders In Response To Airborne Prey Vibrations, Sarah Han, Todd A. Blackledge Dec 2024

Directional Web Strikes Performed By Ray Spiders In Response To Airborne Prey Vibrations, Sarah Han, Todd A. Blackledge

University Research

Most orb-weaving spiders use static webs that deform only after flying prey hit the webs. However, ray spiders (Theridiosoma gemmosum) pull orb webs into cones that are loaded with enough elastic energy to snap back like slingshots at accelerations of up to 504 m s−2 once released. We test the hypothesis that ray spiders sense vibrations from flying insects to release their webs and capture prey in mid-flight. We show that spiders release webs in response to live tethered mosquitoes that are not touching silk. Web release is most likely when mosquitoes are in front of the web and within …


Forty-Eight-Month Clinical Outcomes Of Patients Over 60 Years Old In A Prospective, Controlled, Multicenter Study Evaluating Two-Level Cervical Disc Arthroplasty With A Peek-On-Ceramic Artificial Disc, Andrew Park, Richard Guyer, Pierce Nunley, Ashvin Patel, Jad Khalil, James Yue, Arman Khachatryan, K Brandon Strenge, Hyun Bae, Christopher Good, Rick Sasso Dec 2024

Forty-Eight-Month Clinical Outcomes Of Patients Over 60 Years Old In A Prospective, Controlled, Multicenter Study Evaluating Two-Level Cervical Disc Arthroplasty With A Peek-On-Ceramic Artificial Disc, Andrew Park, Richard Guyer, Pierce Nunley, Ashvin Patel, Jad Khalil, James Yue, Arman Khachatryan, K Brandon Strenge, Hyun Bae, Christopher Good, Rick Sasso

Conference Presentation Abstracts

Introduction: Cervical total disc replacement (cTDR) has gained acceptance as a treatment for symptomatic disc degeneration with symptoms of radiculopathy with/without myelopathy. While clinical outcomes of cTDR have consistently been reported to be similar or superior to those of cervical discectomy and fusion, there are limited reports addressing differences related to patient age. The purpose of this study was to compare the 4-year results of two-level PEEKon-ceramic cervical TDR for patients ≥60 years old to those < 60. Materials and Methods: Data were from the prospective Food and Drug Administration (FDA) Investigational Device Exemption (IDE) trial for the Simplify cervical disc. The study included 145 patients who completed 4-year follow-up, of which 124 were < 60 years old at the time of surgery and 21 were ≥60 years. All patients were treated for two-level cervical disc degeneration with radiculopathy and/or myelopathy. Clinical outcome was based on the Neck Disability Index (NDI), neck pain and arm pain intensity scores (10-point scale), and neurologic status. Radiographic measures included flexion/extension (F/E) range of motion (ROM), disc space height, heterotopic ossification, and adjacent-level degeneration based on Kellgren-Lawrence grading. Mean 48-month outcomes for patients ≥60 years old were compared to those of patients < 60. Radiographs were evaluated by an independent lab specializing in image assessment. Results: Of the outcomes reviewed, only one statistically significant difference was detected based on age group. The mean change in F/E ROM from baseline to 48 months at the inferior index level was 3.33° (< 60) and -0.19° (≥60) (p=0.01). At the superior index level, the difference was not significant (1.80° (< 60) vs. 0.12° (≥60); p=0.20). The difference in change in global ROM was also not significant (5.67° (< 60) vs. 0.77° (≥60); p=0.07). Statistically significant differences were not seen for the other outcomes assessed: mean change in NDI, mean change in neck pain, mean change in arm pain. Neurologic status was normal in 93.6% of the < 60 age group and 100.0% of the ≥60 group (p=0.24). The mean change in average disc height from baseline to 48 months was similar in both groups. The distribution of Kellgren-Lawrence grades (none, doubtful, minimal, moderate, and severe) was also similar for each age group for the level above and below the surgical levels (p=0.88 above, p=0.49 below) and the rate of radiographically relevant HO (grade 3 or 4) was comparable between age groups (superior level (p=0.49); inferior level (p=0.20)). Through latest follow-up, there were zero secondary surgical interventions in the ≥60 cohort and 9 in the < 60 cohort. Conclusion: This study found that patients ≥60 years of age who were treated with PEEK-on-ceramic TDR at two levels had comparable clinical and radiographic outcomes to patients < 60 years of age through 4-year follow-up. These results affirm that cervical TDR performs similarly in patients ≥60 versus those < 60, although the small sample size of patients ≥60 years of age is a limitation.


Analysis And Optimization Of Machine Learning Models For Network Intrusion Detection, Willie Lee Waters Dec 2024

Analysis And Optimization Of Machine Learning Models For Network Intrusion Detection, Willie Lee Waters

All Dissertations

Network intrusion detection NID) is a technology that monitors network traffic and identifies abnormal activity. The ability to identify malicious activity can be manifested by application of artificial intelligence and machine learning (ML). This research delved into analysis, development, and optimization of supervised, unsupervised, and reinforcement learning approaches to network anomaly detection. In the past 10 years, there has been a substantial amount of research on supervised learning, a type of ML that is trained from a prelabeled network dataset that tags each sample with benign or abnormal labels. Unsupervised and reinforcement learning research has been minimal.

This study evaluated …


Voices Of Departure: A Phenomenological Study On African American College Students’ First-Year Decisions To Drop Out In Predominantly White Instutions, Adrianne Leigh Meade Dec 2024

Voices Of Departure: A Phenomenological Study On African American College Students’ First-Year Decisions To Drop Out In Predominantly White Instutions, Adrianne Leigh Meade

All Dissertations

This study explored the lived experiences of first- year African American college dropouts from predominantly White institutions (PWIs). Guided by Swail’s Geometric Model of Student Persistence and Achievement, the study examined the factors influencing dropout rates among first- year African American PWI students. The study sought to foster dialogue and drive positive change in higher education, aiming to prevent further dropout rates among this student demographic. This study revealed that African American students who dropped out of predominantly white institutions (PWIs) within their first year faced significant barriers across social, cognitive, and institutional dimensions. By amplifying student narratives, this study …


Adlerian Play Therapy In Schools: Essential Principles For A K-5th School-Based Mental Health Curriculum, Jasmine Major Dec 2024

Adlerian Play Therapy In Schools: Essential Principles For A K-5th School-Based Mental Health Curriculum, Jasmine Major

All Dissertations

In the United States, 70% to 80% of children who need some form of mental health intervention will not receive services. Schools are an environment that can serve as a critical site for mental health prevention and intervention. Adlerian Play Therapy (AdPT) is an evidence-based practice and has demonstrated efficacy in improving children’s social, emotional, and behavioral outcomes. This study sought to support research efforts to include Adlerian Play Therapy as a viable play-based intervention that could be used in school settings, similar to Child Centered Play Therapy. Increasing the utility of AdPT in school settings widens the scope of …


African American Males In Rural Elementary Schools During The Pandemic: Experiences, Challenges, And Strategies For Success, Jessica Lewis Dec 2024

African American Males In Rural Elementary Schools During The Pandemic: Experiences, Challenges, And Strategies For Success, Jessica Lewis

All Dissertations

The present study experimentally examined the impact of the COVID-19 pandemic on elementary African American males living in rural areas. The qualitative study used a phenomenological approach to examine students' perspectives, as understood by the parents and educators (N=10). Using semi-structured interviews and thematic coding, the researcher suggested strategies for successfully closing instructional gaps and meeting the needs of this population moving forward.

The theoretical frameworks that triggered this exploration were Intersectionality, Maslow’s Hierarchy of Needs, and Conflict Theory. The researcher used the theories as a lens to answer the following research questions: (1) How much has COVID-19 revealed the …


Enhancing Ai Ethics Through Integrating Aif360 With Generative Ai, Christina Ieisha Hastings Dec 2024

Enhancing Ai Ethics Through Integrating Aif360 With Generative Ai, Christina Ieisha Hastings

All Dissertations

In recent years, Artificial Intelligence (AI) has brought about significant positive changes in people's lives with respect to convenience and efficiency. The primary aim of AI is to emulate human intelligence in machines, creating a system capable of thinking and replicating human cognitive functions. AI encompasses tasks that mirror human behaviors, such as visual perception, speech recognition, and language translation.

The realm of AI ethics is an evolving and interdisciplinary field dedicated to addressing ethical considerations in AI. The establishment of ethical standards for AI is vital for developing morally upright AI systems and ensuring ethical conduct in AI applications. …


Reframing The Landscape: Robert Smithson's Spiral Jetty, Amy Reid Dec 2024

Reframing The Landscape: Robert Smithson's Spiral Jetty, Amy Reid

All Graduate Reports and Creative Projects, Fall 2023 to Present

This thesis project recognizes Robert Smithson’s contribution to the fields of art and landscape architecture with a nomination to the National Register of Historic Places for Spiral Jetty. The nomination was completed with support from the Utah State Historic Preservation Office, Dia Art Foundation, and Holt/Smithson Foundation.

Spiral Jetty is considered a highly influential work of the Land art genre. At Rozel Point Smithson constructed a 1,500-foot-long and 15-foot-wide earthwork of site-sourced basalt rock and soil. It extends from the shore approximately 600 feet before collapsing twice in a counterclockwise spiral. Smithson carefully selected the site where the earthwork would …


Quantitative Evaluation Of Baseflow Separation Methods Using An Integrated Hydrologic Model: A Case Study In A Snow-Dominated Watershed, Jihad Othman Dec 2024

Quantitative Evaluation Of Baseflow Separation Methods Using An Integrated Hydrologic Model: A Case Study In A Snow-Dominated Watershed, Jihad Othman

All Graduate Reports and Creative Projects, Fall 2023 to Present

Baseflow, commonly referred to as the groundwater contribution to streamflow, constitutes approximately 50% of streamflow in mountainous regions of the Western United States. Accurately quantifying the amount of baseflow is critical for water management and decision-making, as it significantly impacts stream water quality, low flow availability, and ecosystem health. Traditionally, baseflow has been estimated using conceptual and automated baseflow separation methods, which are known to be both arbitrary and ambiguous, posing a challenge to validate them. In this study, we developed an integrated hydrologic model that seamlessly integrated the exchange between surface and subsurface flows to physically quantify the baseflow …


Teaching Methods To Build The Numeracy Skills Of Preschoolers With Disabilities And Complex Communication Needs, Avery Briggs Dec 2024

Teaching Methods To Build The Numeracy Skills Of Preschoolers With Disabilities And Complex Communication Needs, Avery Briggs

All Graduate Reports and Creative Projects, Fall 2023 to Present

This project explored the use of a curriculum that incorporates naturalistic and explicit instructional approaches through literature and direct teaching moments on the numeracy skills of three students with disabilities and complex communication needs. The numeracy skills targeted included patterning and sorting, shape discrimination, and quantity discrimination. This project took place during Extended School Year (ESY), a program that extends the traditional school year to provide services to students with disabilities. Student present levels and progress were assessed through a pretest and posttest given on the first and last days of ESY, in addition to progress monitoring data taken during …


Designing A Robust Lab Scale Electrocoagulation Reactor For Removal Of Micro- And Nanoplastics From Drinking Water, Emmanuel Louis Aduhene Dec 2024

Designing A Robust Lab Scale Electrocoagulation Reactor For Removal Of Micro- And Nanoplastics From Drinking Water, Emmanuel Louis Aduhene

All Graduate Reports and Creative Projects, Fall 2023 to Present

The widespread occurrence of micro and nanoplastics in drinking water sources could cause serious public health issues. These plastics particles, products of industrial operations and weathering of larger plastics, can interact with other contaminants in the environment, leading to more severe environmental pollution. Present drinking water treatment technologies were designed to remove suspended colloids. However, due to the distinct chemical and physical properties of micro and nanoplastics from conventional colloids, it is challenging for traditional chemical coagulation/flocculation/sedimentation process to achieve satisfying removal performance. This report investigates a design of a lab-scale electrocoagulation reactor for the removal of nanoplastics from drinking …


Quantitative Analysis Of Protective Effect Of Resveratrol Against Nanoplastic-Induced Oxidative Stress, Bryan Gustafson Dec 2024

Quantitative Analysis Of Protective Effect Of Resveratrol Against Nanoplastic-Induced Oxidative Stress, Bryan Gustafson

All Graduate Reports and Creative Projects, Fall 2023 to Present

Nanoplastics and microplastics are a growing ecological and health concern due to their widespread prevalence. The effects of these microscopic particles in biological systems primarily relate to their potential to produce reactive oxygen species and interactive effects with other cytotoxic agents. Of particular interest in this work is the effect on mammalian intestinal cells, due to the regular unintentional ingestion of micro- and nanoplastics in the normal western diet. In this study, Caco-2 cells were cultured and exposed to polystyrene particles in vitro as a simple model of the human digestive endothelium.

Resveratrol, a naturally occurring polyphenolic compound, has been …


Selected Projects In Scenic And Props Design, Melanie E. Valera Garcia Dec 2024

Selected Projects In Scenic And Props Design, Melanie E. Valera Garcia

All Graduate Reports and Creative Projects, Fall 2023 to Present

This plan B paper is a compilation of four projects in which I had the opportunity to participate during my years in the master's program, four scenic projects and one on properties. The paper is divided into four chapters: Pinocchio Teatrale, The Boy at the Edge of Everything, Driving Miss Daisy and Ms. Holmes and Ms. Watson Apt 2B. Each chapter has an introduction, a synopsis of the play, a descriptive design process, the execution of its design and a final evaluation.


Professional Portfolio: Assessment Of And Strategies For Improving A Middle School Student’S Mathematics Performance, Gwenyth O. Falck Dec 2024

Professional Portfolio: Assessment Of And Strategies For Improving A Middle School Student’S Mathematics Performance, Gwenyth O. Falck

All Graduate Reports and Creative Projects, Fall 2023 to Present

This project explores strategies to help secondary students with disabilities improve their mathematics performance. With eighth-grade math scores trending downward and algebra serving as a critical gateway to higher education, target interventions are needed. The literature review highlights two main instructional methods: the Explicit Inquiry Routine (EIR) and the Concrete-Representational-Abstract Integration (CRA-I). Both incorporate physical and virtual manipulatives. These approaches have been shown to help students grasp algebraic concepts, retain what they have learned and apply the skills to new types of problems.

In addition to the research review, this paper includes assessment and intervention reports for a seventh-grade student …


Estimating The Impacts Of Utah's Down Payment Assistance Program (Sb240): A Framework For Analyzing State And Regional Dpa Policies, Dylan Fallentine Dec 2024

Estimating The Impacts Of Utah's Down Payment Assistance Program (Sb240): A Framework For Analyzing State And Regional Dpa Policies, Dylan Fallentine

All Graduate Reports and Creative Projects, Fall 2023 to Present

I examine the impact of Utah's Senate Bill 240, a targeted down payment assistance program for new homes priced under $450,000, on housing affordability and developer behavior. Using Synthetic Difference-in-Differences, Bayesian Structural Time-Series, Fixed Effects Difference-in-Differences, and Event Study Analysis, I assess whether SB240 influenced the construction of more affordable homes and led to reduced lot sizes, thereby fueling affordability.

My empirical analysis reveals that SB240 significantly reduced the transaction price of entry-level new homes in Utah, with an estimated average reduction of approximately $23,000. This effect is robust across various econometric models and data pools, indicating that the policy …


Equivalent-Area Studies For Sonic Boom Loudness Mitigation On A Commercial Supersonic Aircraft Configuration, Zachary N. Foster Dec 2024

Equivalent-Area Studies For Sonic Boom Loudness Mitigation On A Commercial Supersonic Aircraft Configuration, Zachary N. Foster

All Graduate Reports and Creative Projects, Fall 2023 to Present

Since the early 1970s, the FAA has banned commercial supersonic flight over populated areas. This ban has limited aerospace manufacturers’ and commercial aircraft companies’ ability to design and operate subsonic aircraft in their fleets. Since then, research has been conducted to understand the sonic boom and learn how to minimize its loudness. The work presented in this project report aims to use a 1D low-fidelity analysis to study the effect of perturbations to the outer mold line (OML) of a representative model of the N+2 Quiet Commercial Supersonic Concept Aircraft. Using a 1D analysis that employs an equivalent area method, …


An Analysis Of Psychological Concepts In Interactive Media, Kieryn Funk Dec 2024

An Analysis Of Psychological Concepts In Interactive Media, Kieryn Funk

Undergraduate Honors Capstone Projects

An analysis of how video games display psychological concepts and facilitate psychological experiences. Video games are an extremely competent medium for experiences and learning psychology due to the manner in which they elicit emotions and teach procedurally. Psychological concepts are explained in a brief way, then specific examples are brought up from video games connecting the concept to an element in the game, specifically in gameplay mechanics, narrative story, or aesthetics and elements in the game world. Behavioral science is examined both on a conceptual level and on a technical level showing how video games, in general, display the theories …


Viking And Native North American Interactions: The Spread Of Disease In The Norse Discovery Of North America, Sarah N. Haughawout Dec 2024

Viking And Native North American Interactions: The Spread Of Disease In The Norse Discovery Of North America, Sarah N. Haughawout

Undergraduate Honors Capstone Projects

This paper evaluates the potential for spread of disease in the Norse and Native North American interactions around 1000 CE. At this time, the Vikings were expanding their territory in search of land and natural resources following the Viking Raids in mainland Europe. They traveled to Iceland, then Greenland, and finally the eastern coast of northern Canada. Norse explorers faced numerous obstacles on their journeys, but they still prospered in North America for a time. The Vikings hunted the land and sea mammals, used the land, and found ways to thrive while having hostile relations and contact with the Native …


Analysis Of Contemporary Choral Music, Meghan Hatfield Dec 2024

Analysis Of Contemporary Choral Music, Meghan Hatfield

Undergraduate Honors Capstone Projects

This capstone is a culmination of work from the past two years to create an upper-level music theory elective called “Analysis of Contemporary Choral Music.” In this document, I will describe the process of designing the course, how it was implemented, how I participated in the teaching of the course, and what I learned through each process.

This project, which I started in the fall of 2022 as an URCO grant, was created with three goals in mind:

  1. Getting more choral music into music theory classrooms
  2. Getting more music theory into choral classrooms
  3. Doing these things while reflecting the diversity …


Asian American Reproductive Rhetorics: A Rhetorical Analysis Of "The Farm" By Joanne Ramos, Mckinlee Armstrong Dec 2024

Asian American Reproductive Rhetorics: A Rhetorical Analysis Of "The Farm" By Joanne Ramos, Mckinlee Armstrong

Undergraduate Honors Capstone Projects

Rhetorical scholars have long analyzed the idea of choice in the context of reproductive rights and have concluded that individual choice does not override the systematic barriers women of color face in accessing reproductive healthcare. Most Asian American rhetorical artifacts that have reached this same conclusion are case studies. I propose that analyzing Asian American fiction, specifically The Farm by Joanne Ramos, is just as necessary because fiction demonstrates the barriers that might exist in the future and how to prevent them from happening. The framework I use to analyze this text is the Asian American rhetorical concept of restiveness, …


The Feminist Cultural Exchange Between Japan And The United States: A Study Of Articles 14 And 24 In The Japanese Constitution, Kiara Adams Dec 2024

The Feminist Cultural Exchange Between Japan And The United States: A Study Of Articles 14 And 24 In The Japanese Constitution, Kiara Adams

Undergraduate Honors Capstone Projects

This paper explores the feminist cultural exchange between the United States and Japan, focusing on how this exchange has shaped each country’s respective feminist movement. A central component of the paper is its examination of the histories of women’s rights in both nations, shaped by key historical events such as war, economic crises, and feminist activism, and how these histories have influenced current gender policies. It also explores how cultural narratives, including the creation myths of Japan and the U.S., have defined gender roles and women’s rights in each country. Through historical analysis, the paper examines the reciprocal influence between …


Storytelling Through Usu's 10-Minute Play Festival, Sarah Anne Polizzotto Dec 2024

Storytelling Through Usu's 10-Minute Play Festival, Sarah Anne Polizzotto

Undergraduate Honors Capstone Projects

The 10-Minute Play Festival served as the culminating experience of my undergraduate education, combining my skills in stage management, directing, dramaturgy, and arts administration. The project aimed to create an accessible, student-led theatrical event that celebrated inclusion, storytelling, and collaboration. This portfolio highlights both the creative and administrative aspects of my work, showcasing the planning, research, and execution necessary to bring the festival to life. As the festival’s student organizer, I handled administrative tasks such as securing performance rights, designing promotional materials, and coordinating rehearsals. Drawing from dramaturgical research, I developed a vision for my directed play, Three Drunk Poets …


Mapping The Spread: Analyzing The Invastion Of Potamogeton Crispus In The Provo River Delta (2023-2024), Chloe Francis Dec 2024

Mapping The Spread: Analyzing The Invastion Of Potamogeton Crispus In The Provo River Delta (2023-2024), Chloe Francis

Undergraduate Honors Capstone Projects

This capstone project analyzed the spread and ecological impacts of curly-leaf pondweed (Potamogeton crispus) in the Provo River Delta, contributing to the broader Provo River Delta Restoration Project. Field surveys, R programming for data analysis, and spatial mapping through ArcGIS Online were used to create a StoryMap that visualized the presence and absence of curly-leaf pondweed in the delta. A literature review was conducted to gather relevant scientific information on curly-leaf pondweed, which was then synthesized into a fact sheet focused on practical control methods. This fact sheet was presented to managers at the Great Salt Lake Managers …


Dynamic Key-Based Privacy-Preserving Authentication Scheme For Internet Of Drones, Zain Chaudhary Dec 2024

Dynamic Key-Based Privacy-Preserving Authentication Scheme For Internet Of Drones, Zain Chaudhary

Honors Theses

The Internet of Drones (IoD) proliferation has catalyzed transformative changes across various industries, from agriculture to urban management. However, expanding drone networks also presents significant security challenges concerning secure communication and authentication. This paper introduces a robust privacy-preserving key-based authentication scheme tailored explicitly for the IoD, utilizing a matrix key generated by Hierarchical Message Authentication Codes (HMAC) and the SHA-256 algorithm to address these vulnerabilities. Our system enhances security by ensuring each drone in the network can authenticate securely and reliably with a central unit, preventing unauthorized access and securing communications against common threats like eavesdropping and impersonation attacks. Our …


Advancing Grid Modernization Through Data-Driven Resilience Modeling And Hosting Capacity Of Distributed Energy Resources, Oscar Samuel Acosta Dec 2024

Advancing Grid Modernization Through Data-Driven Resilience Modeling And Hosting Capacity Of Distributed Energy Resources, Oscar Samuel Acosta

Open Access Theses & Dissertations

This Ph.D. dissertation focuses on advancing the integration of distributed energy resources (DERs) through concepts surrounding their impacts on power system stability, resilience, and hosting capacity (HC). This dissertation addresses crucial topics in renewable energy deployment, transient fault response, and dynamic modeling. The work begins with the development of renewable energy source (RES) models tailored for offsetting residential heating, ventilation, and air conditioning~(HVAC) and commercial cooling loads. These models utilize solar photovoltaic (PV) and wind energy systems to produce scalable frameworks adapted across diverse climates and building types in application of a partial-load targeting methodology. The dissertation then transitions from …


Mechanical Stability Of Body-Centered Cubic Iron At Earth's Core Pressure And Temperature Conditions Using A Molecular Graph Kernel Regression And Gaussian Process., Blaise Awola Ayirizia Dec 2024

Mechanical Stability Of Body-Centered Cubic Iron At Earth's Core Pressure And Temperature Conditions Using A Molecular Graph Kernel Regression And Gaussian Process., Blaise Awola Ayirizia

Open Access Theses & Dissertations

We used machine learning to study nonmagnetic BCC iron in conditions similar to thosefound in the Earthâ??s core. Our model predicts the stability of BCC iron at high temperatures and pressures by analyzing a dataset from ab initio molecular dynamics simulations. The framework uses Gaussian process regression to make predictions by comparing the similarity between molecules. This comparison is made using the marginalized graph kernel. To use the marginalized graph kernel, the framework applies a spatial adjacency rule to convert molecules into graphs, where the vertices and edges are labeled by elements and interatomic distances, respectively. We can use this …


D-Optimal Joint Best Linear Unbiased Predictors In Progressively Type-Ii Ordered Statistics, Tamim Alam Dec 2024

D-Optimal Joint Best Linear Unbiased Predictors In Progressively Type-Ii Ordered Statistics, Tamim Alam

Open Access Theses & Dissertations

Reliability and life-testing experiments play a crucial role in understanding the longevity and performance of systems and components, particularly in high-stakes applications such as engineering, manufacturing, and quality control. In this thesis, we focus on the prediction of future unobserved failure times by employing joint predictors based on progressively Type-II censored data obtained from such life-testing experiments. Specifically, we derive explicit analytical expressions for the joint best linear unbiased predictors (BLUPs) of two future order statistics under the D-optimality criterion. The derivation involves minimizing the determinant of the variance-covariance matrix of the predictors within the context of progressively Type-II censored …


Developing A Bioengineered Nanoparticle For Improving Oral Absorption Of Iron Supplements., Mila Biswas Dec 2024

Developing A Bioengineered Nanoparticle For Improving Oral Absorption Of Iron Supplements., Mila Biswas

Open Access Theses & Dissertations

Iron deficiency (ID) and iron deficiency anemia (IDA) are widespread nutritional issues, affecting millions globally. Conventional iron supplements often suffer from low absorption rates and gastrointestinal side effects. We investigated β-glucan derivatives as potential carriers to enhance iron absorption and mitigate these drawbacks. This study explored a novel β-glucan-based carrier system loaded with ferrous sulfate heptahydrate. In-vitro studies demonstrated sustained iron stability for over six hours in simulated gastric fluids due to the carrier's affinity for stomach mucin. Particle size analysis and scanning electron microscopy (SEM) images confirmed this specific binding. Additionally, drug release studies revealed a pH-dependent release profile, …