Impact Of Urban Development On Uv Exposure: A Clustering And Machine Learning Assessment, Taufik Roni Sahroni Mr., Verdi Yasin, Lulut Alfaris, Reza Ariefka, Ruben Cornelius Siagian, Mohammad Alfin Karim, Nana Rahdiana, Ade Suhara

Journal of Environmental Science and Sustainable Development

The relocation of Indonesia's capital city is anticipated to promote inclusive economic growth while embracing cultural diversity. However, this transition may affect ultraviolet (UV) radiation exposure patterns. The study investigated variations in UV exposure in the IKN region, focusing on urban development factors such as land use and population density that affect public health, sun protection, and skin cancer prevention. The research hypothesized that UV radiation is significantly correlated with these factors. UV Index data from 2010-2023, a hierarchical clustering method, identifies complex data patterns without determining the number of clusters. XGBoost, a machine learning model, was used for handling …

Road Safety Assessment For Accident And Non-Accident Cases Supporting Sustainable Development Goals 2030, Brian Nararya Nugraha, Sekar Warangi Nurcahyati, Hizkia Adhikaratma, Martha Leni Siregar

Journal of Environmental Science and Sustainable Development

Halving the number of global deaths and injuries from road traffic accidents is one target of the Sustainable Development Goals 2030, which is still a challenging problem in Indonesia. However, the majority of research on this topic uses accident-based methods, which limits the safety analysis. Two road safety assessment methods are used to close the gap, with the addition of non-accident-based methods such as Road Safety Audits (RSA). The Margonda Raya Road, which is categorised as a traffic accident blackspot, was selected for the case study. For this, a field survey of the road segment is carried out. To minimise …

Evaluation Of Microbial Contamination In Tube Well And Filter Water Of Lahore And Treatment With Copper Nanoparticles, Khadeeja Moazzam, Sumaira Mazhar

Journal of Bioresource Management

Water contamination is a global issue and different techniques are being devised to reduce water contamination. Among these techniques, use of nanoparticles for water purification is an efficient and cost-effective method with minimum or no side effect. Metal nanoparticles are known for their antibacterial activity against various pathogens. Synthesis of these nanoparticles using green synthesis methods minimizes the harmful effects while ensuring their antibacterial activity. Therefore, in the present work, it was aimed to evaluate the microbial contamination in water samples collected from different tube wells and filter plants located in different areas of Lahore, Pakistan for the isolation of …

Raw Milk Collection Diversity And Determinants Of Physicochemical And Microbiological Quality In Algerian Small Farms, Nasria Benamara, Houari Yerou, Hamza Belkhodja, Toufik Madani

Journal of Bioresource Management

Milk sector in Algeria presents lasting supply instability and its development policy has not achieved the expected results. The interest in developing local dairy production therefore has been a priority for public authorities. Our work aims to analyze raw milk collection diversity at the GIPLAIT dairy in Tizi (Mascara) and assess their physicochemical and microbiological quality. The typology of raw milk collection was determined from upstream, the farm to the dairy processing factory. The quality of the milk was determined by carrying out both physicochemical analyses (pH, Dornic acidity, butter content, protein content, density and total dry extract) and microbiological …

Green Design Of Plant Based Pharmaceutical Drugs: Example Of A Wound Healing Topical Cream With Plectranthus Bojeri (Benth) Hedge Lamiaceae Extract, Helga Rim Farasoa, Marie Louise Razafindravao, Rojo Fanambinantsoa Andriamiarantsoa, Gerard Cecilien Raboanary, Jean Marie Razafindrakoto, Voahangy Ramanandraibe Vestalys

Journal of Bioresource Management

To ensure the perennity of natural resources, the valorisation process of herbal pharmaceuticals must be assessed for sustainability from the very beginning of its design. No specific tools have been developed for this particular field so far. We demonstrate in this study that existing green design tools can be adapted to evaluate plant-based products manufacturing process. As the example of a topical cream using Plectranthus bojeri (Benth) Hedge LAMIACEAE extract was considered, we first confirmed the traditional use of this plant for wound healing. It acts by accelerating the re-epithelialisation phase. Using the Vermeer Cosmolife version 0.24 software tool the …

Exploring Antibiotic Resistance And Exopolysaccharide Production In Bacillus Paramycoides From Wastewater, Zainab Hassan, Nazia Jamil, Rida Batool

Journal of Bioresource Management

Antibiotics have been found extensively in the environment, particularly in groundwater, sediments, and surface water. The purpose of this study was to isolate and identify antibiotic-resistant bacteria from wastewater collected from sewage (Sher Shah Colony, Raiwind) and an industrial area (Hudiara Drain Gajju Matta) in Lahore. Ten bacterial strains (Z1, Z2, Z3, Z4, Z5, Z6, Z7, Z8, Z9, and Z10) were isolated from the samples. All of these strains were gram-positive. Antibiotic resistance profiling showed that strain Z1 was most resistant to ampicillin (1500 μg/ml) among all of the antibiotics (tetracycline, penicillin, erythromycin, and chloramphenicol) that were tested. A growth …

Ethephon Application And Nitrogen Optimization Through Foliar Urea For Okra Production, Muhammad Usaid, Muhammad Yaisr Ali, Ihsan Ul Haq, Sajid Ali, Huzaifa Ihsan, Arslan Rafique, Kalim Ullah, Khalid Nisar, Khan Badshah, Mian Muhammad Huzaifa, Muhammad Shoaib Muteezai

Journal of Bioresource Management

To mitigate the environmental impact of excessive urea use, this study investigates the foliar application of urea and ethephon as a more efficient alternative to soil application, aiming to optimize nitrogen use while sustaining the growth and yield of okra. The research was conducted using a randomized complete block design with two factors, replicated four times. Factor A included ethephon levels with a control (E0 = Control, E1 = 150 ppm, E2 = 250 ppm, E3 = 350 ppm), while Factor B comprised two urea levels and a control (U0 = Control, U1 = 1%, U2 = 2 %). The …

Determination Of Manganese Concentration In Forages, Soil, Sewage Water Of Three Suburban Areas Of Sargodha, Pakistan, Iqra Anwar, Zafar Iqbal Khan, Kafeel Ahmad, Naila Riaz, Faiza Zubair, Asma Ashfaq, Muhammad Fahad Ullah, Farzana Siddique, Ijaz Rasool Noorka, Abid Ejaz, Maloofa Manzoor, Umbreen Bibi, Hafiza Memona Nazir, Saif Ullah

Journal of Bioresource Management

For irrigation of soil utilization of wastewater has risen significantly in the past few years. This wastewater often have large amount of trace elements and heavy metals, many of which are non-essential and harmful to living organisms such as plants, animals, and humans. In Pakistan, particularly around suburban areas, it is common to use this polluted water for growing vegetables. When such water is used for irrigation over an extended period of time, toxic substances can accumulate in the soil, potentially causing toxicity to plants and degrading soil quality. The samples analyzed in the study were prepared using the wet …

Saatnya Memberikan Vaksin Influenza Untuk Tenaga Kesehatan, Anshari Saifuddin Hasibuan

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Analisis Prediktif Mutasi Egfr Pada Adenokarsinoma Paru Menggunakan Pendekatan Pembelajaran Mesin, Edwin Nugroho Njoto, Yuri Pamungkas, Atina I.W. Putri, Muhammad. Najib Haykal, Dwinka Syafira Eljatin, Edith Maria Djaputra

Jurnal Penyakit Dalam Indonesia

Introduction. Lung adenocarcinoma is a prevalent form of lung cancer, and mutations in the epidermal growth factor receptor (EGFR) gene are known to play a crucial role in its pathogenesis. This study aimed to develop a machine-learning model to predict EGFR mutations in lung adenocarcinoma patients using clinical and radiological features.

Methods. A case-control study was conducted using a dataset comprising 160 patients with lung adenocarcinoma. Several machine learning algorithms, including decision tree, linear regression, Naive Bayes, support vector machine, K-nearest neighbor, and random forest, were employed to predict EGFR mutations based on variables such as smoking status, …

Efektivitas Vaksin Covid-19 Mrna Booster Kedua Pada Tenaga Kesehatan Di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo Dan Faktor Yang Memengaruhinya, Siti Taqwa Fitria Lubis, Sukamto Koesnoe, Evy Yunihastuti, Hamzah Shatri, Teguh Harjono Karjadi, Kuntjoro Harimurti, Ceva Wicaksono Pitoyo, Em Yunir

Jurnal Penyakit Dalam Indonesia

Introduction. The emergence of the Omicron variant during the pandemic had an impact on the effectiveness of the COVID-19 vaccine. The spread of Omicron increased rapidly even in populations that had been vaccinated with booster doses, causing a high incidence of infection. This study aimed to determine the effectiveness and factors related to the effectiveness of the second mRNA booster vaccine as well as antibody levels after the second mRNA booster vaccine in healthcare workers at Cipto Mangunkusumo National General Hospital.

Methods. This study used a cohort design. Total sampling of 271 healthcare workers were obtained from previous …

Efek Terapeutik Analog Somatostatin Dalam Menghambat Perkembangan Autosomal Dominant Polycystic Kidney Disease, Irvin Rembrant Holleritz Sitompul, Grasella Angelika Putri, Purwita Wijaya Laksmi

Jurnal Penyakit Dalam Indonesia

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a hereditary disorder characterized by formation and progressive growth of cysts in the kidneys and other organs such as liver, spleen, and pancreas. Recent advances have led to possibilities to target the main cause of cyst growth, cAMP. Somatostatin targets cAMP and inhibits its production directly and indirectly in kidney and liver, which might potentially prevent renal and liver cyst progression in ADPKD. This report aims to evaluate the effectiveness of somatostatin analogue therapy in slowing disease progression in ADPKD patients, according to the latest evidence. A literature search was conducted on five …

Long Covid Dan Sistem Kardiovaskular, Muhadi Muhadi, Ivan Mardhi Laksmana

Jurnal Penyakit Dalam Indonesia

Even after nasopharyngeal Polymerase Chain Reaction (PCR) swab investigation revealed no COVID-19 infection, some individuals continue to have long COVID symptoms. According to a research published in 2022, 4.5 – 36.6% of patients had symptoms following a COVID-19 infection more than three months. Long COVID symptoms may impact multiple organ systems, including the cardiovascular system. Chest pain, palpitations, arrhythmia, postural orthostatic tachycardia syndrome, and other symptoms are possible appeared in long COVID. D-Dimer, echocardiography, CT scan, cMRI and other supportive test showed meaningful results. Pharmacological treatment can be given based on the concurrent diagnosis found in patients with long COVID. …

Self-Assessment Of Ophthalmology Competency Among Thai Medical Interns, Pakornkit Phrueksaudomchai, Passawut Tokeaw

Asian Medical Journal and Alternative Medicine

Introduction: Ocular issues encountered in general practice significantly impact patients’ health and quality of life. However, Thai medical undergraduate programs dedicate only 1-2 weeks to ophthalmology rotation, potentially impacting students’ knowledge, skills, and confidence in managing patients with eye problems. Despite this potential concern, limited empirical evidence on students’ competency exists. This study investigates the knowledge, skills, and confidence of medical interns in ophthalmology to inform curriculum development within Thailand’s medical schools.

Objectives: To evaluate ophthalmology competency of Thai medical interns through self-assessment questionnaires.

Methods: A cross-sectional descriptive design was used to survey 160 medical interns who graduated from Thai …

Pseudomonas Aeruginosa And Its Resistance, Thana Khawcharoenporn

Asian Medical Journal and Alternative Medicine

No abstract provided.

Clinical Characteristics And Treatment Outcomes Of Primary Aldosteronism In A Tertiary Hospital In Thailand, Peeradon Vibhatavata, Nuttapong Namfa, Kanokporn Sanpawithayakul

Asian Medical Journal and Alternative Medicine

Background: Primary aldosteronism (PA) is the most common cause of endocrine hypertension, increasing cardiovascular and renal risks. This study aimed to provide comprehensive information on PA patients in Thailand, where data are limited. Materials and A retrospective study of 127 PA patients during 2012 to 2023 from Thammasat University

Methods: Hospital was conducted. Data on clinical and biochemical parameters, screening, confirmatory testing, subtype classification, and treatment outcomes were evaluated.

Results: Fifty patients (39%) had unilateral PA, 50 (39%) bilateral PA, and 27 (21%) were classified as inconclusive subtype. Mean age was 54 years, and 54% were female. All participants had …

Effect Of Benzalkonium Chloride And Chlorhexidine On The Antibiotic Susceptibility Of Pseudomonas Aeruginosa, Thitinan Phutthilertmethawee, Potjanee Srimanote, Pholawat Tingpej

Asian Medical Journal and Alternative Medicine

Introduction: The transmission of Pseudomonas aeruginosa can be controlled using biocides such as benzalkonium chloride (BKC) and chlorhexidine (CHX). However, debates continue over whether biocide exposure contributes to the development of antibiotic resistance.

Objectives: To investigate the impact of BKC and CHX exposure on the development of antibiotic resistance in P. aeruginosa.

Methods: The minimal inhibitory concentrations (MICs) of P. aeruginosa PAO1 (ATCC27853) and 15 clinical isolates against BKC and CHX were determined. The bacteria were grown in media containing subinhibitory concentrations (SICs) of these biocides for five consecutive passages. MICs for ciprofloxacin, ceftazidime, and gentamicin, …

Incidence And Risk Factors Of Iatrogenic Pneumothorax After Thoracentesis In Medical Wards: A 1-Year Prospective Single-Center Study, Phattaraphol Limsakul, Nathaorn Phuangsombut, Pattarin Pirompanich

Asian Medical Journal and Alternative Medicine

Introduction: Iatrogenic pneumothorax (IP) after thoracentesis can lead to life-threatening conditions and increased treatment costs. Understanding the associated risk factors is crucial for prevention.

Objectives: This study aims to investigate the incidence of IP and its contributing risk factors.

Methods: This one-year prospective consecutive study was conducted in a tertiary teaching hospital, documenting all thoracentesis procedures performed in the medical wards from July 2021 to June 2022.

Results: Data were collected from a total of 47 procedures involving 39 patients, with a mean age (SD) of 69.4 (13.9) years. Among the patients, 21 (53.9%) were male. The incidence of IP …

Prevalence Of Coronary Artery Calcification In Non-Ecg Gated Staging Chest Ct Scans Of Patients With Primary Lung Cancer, Warit Tarathipmon, Wattanai Amnuaysin

Asian Medical Journal and Alternative Medicine

Introduction: Patients with primary lung cancer have an elevated risk of cardiovascular disease, which requires further assessment. In which, a non-ECG-gated chest CT scan performed for lung cancer staging may be used to reveal coronary artery calcification.

Objective: The objective of this study was to determine the prevalence of coronary artery calcification using a non-ECG gated staging chest CT scan in patients with primary lung cancer.

Methods: A retrospective review of fifty-one patients with primary lung cancer and at least one staging chest CT was carried out from May 1, 2020, to August 31, 2021, in Thammasat University Hospital. The …

Prevalence Of Hematoma Expansion And Signs In Non-Contrast Computed Tomography For Predicting Hematoma Expansion In Spontaneous Intracerebral Hemorrhage At Siriraj Hospital, Dittapong Songsaeng, Sirirat Yuyod, Sittaya Buathong, Kullathorn Thephamongkhol, Wassana Peuksiripibul, Sastrawut Thammakittiphan

Asian Medical Journal and Alternative Medicine

Introduction: Hematoma expansion (HE) in intracerebral hemorrhage (ICH), defined by over 33% or > 6 ml volume increase, often leads to poor outcomes and mortality. This study aims to examine non-contrast computed tomography (NCCT) indicators for HE prediction and their associations with patient clinical data and HE occurrence.

Methods: We retrospectively analyzed data and measured HE by using image analysis software in NCCT images including initial and follow-up scan at <7 days from 169 patients during Jan 2013 - Aug 2019 in Siriraj Hospital.

Results: HE was found in 44 of the 169 patients with spontaneous ICH (26%), occurring in two periods: at 10–25 h (peak 7 h) and at 50–75 h (peak 50 h). …

The Cerebral To Middle Cerebellar Peduncle Width Ratio: An Imaging Biomarker For Differentiating Multiple System Atrophy From Degenerative Parkinsonism, Shinnaphat Wattanasin, Praween Lolekha

Asian Medical Journal and Alternative Medicine

Introduction: The differentiation between Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS) is clinically challenging. Magnetic resonance imaging (MRI) measurement of the cerebral peduncle (CP) and middle cerebellar peduncle (MCP) axial widths have not been investigated. The objective was to evaluate the utility of the CP and MCP axial widths in the differentiation of degenerative parkinsonian syndromes and their clinical correlations.

Methods: The CP and MCP were retrospectively measured based on the axial T1-weighted MRI in 100 patients with probable PD, multiple system atrophy (MSA), progressive supranuclear palsy, Lewy body dementia, or Alzheimer’s disease from the movement disorders clinic at …

Nutritional Support Leading To The Accomplishment Of Treatment Goal: A Case Report Of Recurrent Locally Advanced Breast Cancer, Panuch Eiamprapaporn, Kanokkarn Chupisanyarote

Asian Medical Journal and Alternative Medicine

A 56-year-old woman with recurrent locally advanced breast cancer (rcT1a N3a M0, Luminal B) underwent curative intent treatment. Oral nutritional support (ONS), which was an immune-nutrition formula, was implemented to optimize her nutritional status and support treatment tolerance. This case highlights the importance of nutritional support in improving treatment outcomes for patients with recurrent breast cancer.

Editor's Note, Thana Khawcharoenporn

Asian Medical Journal and Alternative Medicine

No abstract provided.

Prosthetic Valve Endocarditis With Cardiobacterium Hominis: A Case Report, Kaci Griffin, Timothy Jang, Rees Adomako, Jasmine R. Marcelin, Jonathan H. Ryder

Graduate Medical Education Research Journal

Background: Cardiobacterium hominis (C. hominis) is an uncommon cause of infective endocarditis and often presents sub-acutely with fevers, cardiac murmurs, or embolic phenomena. We present a rare case of C. hominis infective prosthetic valve endocarditis that presented with new-onset atrial flutter and systemic emboli.

Case: A 38-year-old male presented to the emergency department with palpitations, shortness of breath, and chest tightness and was found to be in atrial flutter. He underwent a transesophageal echocardiogram-guided cardioversion and was incidentally found to have a one-centimeter echodensity on the ventricular side of his prosthetic aortic valve. (Figure 1.) He …

Pumping Iron, Straining Hearts: Androgen Building Cardiomyopathy In A Middle Aged Bodybuilding Enthusiast, Milan Terzic, Yash B. Patel

Graduate Medical Education Research Journal

A 46-year-old bodybuilder presenting with new onset dyspnea found to have a new onset non-ischemic cardiomyopathy (CM) attributed to exogenous trenbolone and testosterone use. Steroid cessation and guideline-directed heart failure therapy led to notable recovery in left ventricular function supported by global longitudinal strain, ejection fraction and symptomatology.

Anabolic steroid-induced CM involves multiple mechanisms including lipid disturbances, hypertrophy, reduced receptor sensitivity, and cell damage. This case emphasizes the importance of recognizing anabolic steroid misuse as a potential cause of non-ischemic cardiomyopathy in middle aged men. With prompt discontinuation of steroids, remained abstinence and early initiation of guideline-directed medical therapy, myocardial …

Effective Strategies In Improving Internal Medicine In-Training Exam Performance - A Systematic Review, Derek Clar, Ryan Juneau, Valentina Mcneal, Dhara Patel, Prutha Patel, Amro Ilaiwy

Graduate Medical Education Research Journal

Background: The IM-ITE is administered annually to provide residents and program leadership with a measure of the residents' knowledge compared with that of their peers nationwide. Several approaches have been used to improve IM-ITE scores as a means of achieving higher first-time board examination pass rates. While these interventions helped improve outcomes in target programs, it remains unclear whether one approach was superior to another and how different program demographics may have played a role in the outcome of the intervention. Objective: To identify the most effective methods used to improve IM-ITE scores in the literature. Methods: We searched MEDLINE …

Perioperative Outcomes And Mortality In Liver Transplant Patients 65 And Older, Nathaniel S. Pester, Trevor J. Wilke, V K. Shostrom, Cale A. Kassel

Graduate Medical Education Research Journal

Background: The number of patients over the age of 65 awaiting liver transplantation (LT) continues to grow and an increasing number of patients will undergo liver transplantation. While age is not an absolute contraindication to liver transplantation, understanding the risks to older patients remains essential to ensure good outcomes with the limited number of grafts available.

Methods: This retrospective study included patients undergoing LT at the University of Nebraska Medical Center. A total of 421 patients were enrolled and stratified to patients under 65 years old (351 patients) and patients over 65 (70 patients). Geriatric patients were defined as aged …

Wilson’S Disease Presenting As Acute Hepatitis In Pregnancy With Successful Maternal And Neonatal Outcomes: A Case Report, Paribesh Gyawali, Ranjan Regmi, Shambu Khanal, Rajan Bhandari, Shivani Gupta, Gunjan Arora

Graduate Medical Education Research Journal

Background: Wilson’s disease is a rare genetic disorder characterized by copper accumulation, leading to multi-organ symptoms. It affects between 1 in 30,000 to 1 in 100,000 individuals, with a mean age at diagnosis of 13.2 years. The diagnosis may be overlooked due to its numerous presentations, which can range from non-specific symptoms such as fever, fatigue, and behavioral changes to fulminant hepatic failure. Its clinical manifestations vary widely, making diagnosis during pregnancy particularly challenging. Wilson’s disease complicates pregnancy, as untreated cases can lead to significant morbidity and mortality; excess copper can disrupt metabolic processes and contribute to recurrent miscarriages.

Case: …

A Retrospective Analysis Of The Effects Of Pneumonia And Chronic Obstructive Pulmonary Disease On Patient Mortality In Southwest Missouri, Cameron Smith, Monika Ziogaite, Lindsay Doolan-Mattice, Heather Vonhegel, Mariam Akhtar, Nova Beyersdorfer, Kerry Johnson, John Paulson

Student Publications

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease. In this study, we aimed to explore the effects of COPD and pneumonia on the mortality rates among patients admitted to the Freeman Health System in Southwest Missouri, to provide a better idea of whether there is a correlation between the two and whether the presence of both adds to the mortality rates. Patient data were extracted from electronic medical records, focusing on patients with or without COPD and pneumonia diagnoses. Analyses revealed a statistical difference, with a p-value of <0.0001, in mortality rates between COPD patients with (P1) and without (P3) pneumonia, indicating that pneumonia did have an impact on COPD patients. However, pneumonia patients without COPD (P2) had a higher, but non-statistical difference in mortality rates compared to COPD patients with pneumonia (P1), with a p-value of 0.0806. These findings emphasize the severe influence of pneumonia in both COPD and non-COPD populations in the area, warranting further investigation and emphasizing the importance of timely and appropriate treatment. These results provide insights into the interplay between COPD and pneumonia in the geographic area, which may provide guidance in treatment decisions that may improve patient outcomes.

Ai-Assisted Academia: Unveiling Doctoral Students' Perspectives On Dissertation In Practice Innovation, Jennifer J. Lesh, Jévaughn J. Lancaster

Faculty and Staff Publications & Presentations

This action research study explores 73 doctoral students' perceptions of using Generative Artificial Intelligence (GAI) throughout their research journey in one educational doctorate (Ed.D) program. The first phase employed surveys, while the second incorporated semi-structured focus group interviews based on the survey data from a diverse sample of students across educational disciplines currently enrolled in the university's educational leadership doctoral program. In the study's first phase, the survey quantified educators' familiarity with, attitudes towards, perceived challenges, ethical considerations, and benefits of using GAI in doctoral research. The exploration of GAI in this practitioner-inspired doctoral program has uncovered essential insights into …