Digital Commons Network^™

Keygan: Synthetic Keystroke Data Generation In The Context Of Digital Phenotyping, Alejandro Acien, Aythami Morales, Luca Giancardo, Ruben Vera-Rodriguez, Ashley A Holmes, Teresa Arroyo-Gallego

Faculty, Staff and Student Publications

Objective: This paper aims to introduce and assess KeyGAN, a generative modeling-based keystroke data synthesizer. The synthesizer is designed to generate realistic synthetic keystroke data capturing the nuances of fine motor control and cognitive processes that govern finger-keyboard kinematics, thereby paving the way to support biomarker development for psychomotor impairment due to neurodegeneration.

Methods: KeyGAN is designed with two primary objectives: (i) to ensure high realism in the synthetic distributions of the keystroke features and (ii) to analyze its ability to replicate the subtleties of natural typing for enhancing biomarker development. The quality of synthetic keystroke data produced by KeyGAN …

Inhibition Of Nitric Oxide Synthase Transforms Carotid Occlusion-Mediated Benign Oligemia Into De Novo Large Cerebral Infarction, Ha Kim, Jinyong Chung, Jeong Wook Kang, Dawid Schellingerhout, Soo Ji Lee, Inyeong Park, Dong-Seok Gwak, Ji Sung Lee, Sung-Ha Hong, Kang-Hoon Je, Hee-Joon Bae, Joohon Sung, Eng H Lo, James Faber, Cenk Ayata, Dong-Eog Kim

Faculty, Staff and Student Publications

No abstract provided.

Stat3 Inhibition In Combination With Cd47 Blockade Inhibits Osteosarcoma Lung Metastasis, Pradeep Shrestha, Rejeena Shrestha, You Zhou, Rafal Zielinski, Waldemar Priebe

Faculty, Staff and Student Publications

Background: New therapies are urgently needed for patients with osteosarcoma (OS). STAT3 and CD47 are potential therapeutic target in OS. Here we investigated the therapeutic activity of the orally bioavailable STAT3 inhibitor, WP1066, and anti-CD47 antibody using OS mouse models.

Methods: Cytotoxic effect of WP1066 against OS cell lines and its immunomodulatory effects were evaluated in vitro. Experimental metastasis and orthotopic syngeneic mouse models were used to investigate the therapeutic efficacy of WP1066 and anti-CD47 antibody. Further flow cytometric analysis was performed.

Results: STAT3 was constitutively activated in multiple human and mouse OS cell lines. WP1066 suppressed STAT3 activation …

Incidence Of Bacterial Blood Stream Infections In Patients With Acute Gvhd, Whitney Wallis, Alison M Gulbis, Tao Wang, Catherine J Lee, Akshay Sharma, Taiga Nishihori, Lohith Gowda, Michael Byrne, Maxwell M Krem, Margaret L Macmillan, Carrie L Kitko, Joseph Pidala, Stephen R Spellman, Stephanie J Lee, Amin M Alousi

Faculty, Staff and Student Publications

Bacterial bloodstream infections (BSI) can be a substantial contributor to complications of GVHD treatment. The aim of this study was to determine the risk for BSI from neutrophil engraftment through day 100 post transplant in patients with acute GVHD (AGVHD) based on organ involvement and severity. Patients (n = 4064) who underwent an allogeneic hematopoietic stem cell transplant (HCT) reported to the CIBMTR registry were analyzed. Grade II-IV AGVHD occurred in 1607 (39.5%) patients and was associated with a greater day-100 incidence of post engraftment BSI than with grade 0/I (24.9 vs. 15.3%). Patients with grade III/IV AGVHD had the …

Patient-Reported Outcomes During Pelvic Radiation Therapy: A Secondary Analysis On Sexual Function From Nrg-Rtog 1203, Kelsey L Corrigan, Rebecca Paulus, Ann H Klopp, Lari B Wenzel, Anamaria R Yeung, Desiree E Doncals, Nancy H Wiggers, Dasarahally S Mohan, Sharad A Ghamande, Shannon N Westin, Kara L Schnarr, Michael L Haas, David K Gaffney, Steven E Waggoner, Pamela J Vanderwall, Noha T Jastaniyah, Stephanie L Pugh, Lisa A Kachnic

Faculty, Staff and Student Publications

Purpose: NRG-RTOG 1203 reported that intensity-modulated radiation therapy (IMRT) reduced patient-reported GI toxicities in patients with cervical/endometrial cancer receiving postoperative RT, compared with 3-dimensional conformal radiation therapy (3DRT). We conducted a secondary analysis of patient-reported sexual function (PR-SF) among treatment groups to identify factors associated with sexual dysfunction.

Methods and materials: Patients on NRG-RTOG 1203 were randomly assigned to 3DRT versus IMRT and completed Patient-Reported Outcomes (PRO)-Common Terminology Criteria for Adverse Events (CTCAE) and FACT-Cx surveys at baseline, week 5 of RT, and at 4-6 weeks, 1 year, and 3 years after RT. Patient responses to FACT-Cx sexual function questions …

Ai/Ml-Empowered Approaches For Predicting T Cell-Mediated Immunity And Beyond, Cheng-Chi Chao, Yulun Chiu, Lucas Yeung, Cassian Yee, Chongming Jiang

Faculty, Staff and Student Publications

T cells play a dual role in various physiopathological states, capable of eliminating tumors and infected cells, while also playing a pathogenic role when activated by autoantigens, causing self-tissue damage. The regulation of T cell-peptide/major histocompatibility complex (TCR-pMHC) recognition is crucial for maintaining disease balance and treating cancer, infections, and autoimmune diseases. Despite efforts, predictive models of TCR-pMHC specificity are still in the early stages. Inspired by advances in protein structure prediction via deep neural networks, we evaluated AlphaFold 3 (AF3)-based AI computation as a method to predict TCR epitope specificity. We demonstrate that AlphaFold can model TCR-pMHC interactions, distinguishing …

A New, Early Cretaceous Carettochelyid Turtle From South Korea Provides Insights Into Softshell Evolution And Aquatic Ecology, Minguk Kim, Jongyun Jung, Walter G Joyce, Jae-Il Park, Hye-Yeon Jung, Min Huh

Faculty, Staff and Student Publications

Here, we present a new Cretaceous carettochelyid turtle, Byeoljubuchelys yeosuensis gen. et sp. nov., from the Lower Cretaceous Hasandong Formation of Yeosu, Korea. A nearly complete shell and select elements of the girdles and limbs provide crucial insight into the evolution and aquatic adaptation of this family. Phylogenetic analyses place Byeoljubuchelys yeosuensis at the most basal position within Carettochelyidae. The mid-sized plastron of Byeoljubuchelys yeosuensis appears to be plesiomorphic for the group. The expansion of the plastron during carettochelyid evolution, especially during the Paleogene, may be an evolutionary response to increasing body size or the threat of mammalian predators. …

Tnik-Driven Regulation Of Erk5 Transcriptional Activity In Endothelial Cells, Venkata Subrahmanya Kumar Samanthapudi, Sivareddy Kotla, Nhat-Tu Le

Faculty, Staff and Student Publications

Extracellular signal-regulated kinase 5 (ERK5) is essential for cardiovascular development and endothelial cell (EC) function. Activation of ERK5 through MEK5-mediated phosphorylation at threonine 218 and tyrosine 220 (T218/Y220) drives the transcriptional activation of myocyte enhancer factor-2 (MEF2), promoting the expression of KLF2 and KLF4—key transcription factors that maintain vascular homeostasis. We previously demonstrated that ponatinib suppresses ERK5 transcriptional activity without affecting laminar-flow (l-flow)-induced T218/Y220 phosphorylation, suggesting a non-canonical regulatory mechanism. Since ponatinib inhibits Traf2- and Nck-interacting kinase (TNIK), we hypothesized that TNIK modulates ERK5 transcriptional activity. Using a mammalian one-hybrid assay and quantitative RT-PCR (qRT-PCR), we show that TNIK …

Predicting Sinonasal Inverted Papilloma Attachment Using Machine Learning: Current Lessons And Future Directions, Sean P Mckee, Xiaomin Liang, William C Yao, Brady Anderson, Jumah G Ahmad, Salman Hasan, Chinmay Mokashi, Samia Islam, Amber U Luong, Martin J Citardi, Luca Giancardo

Faculty, Staff and Student Publications

Background: Hyperostosis is a common radiographic feature of inverted papilloma (IP) tumor origin on computed tomography (CT). Herein, we developed a machine learning (ML) model capable of analyzing CT images and identifying IP attachment sites.

Methods: A retrospective review of patients treated for IP at our institution was performed. The tumor attachment site was manually segmented on CT scans by the operating surgeon. We used a nnU-Net model, a state-of-the-art deep learning-based segmentation algorithm that automatically configures image preprocessing, network architecture, training, and post-processing to identify the IP attachment site. The model was trained and evaluated using a 5-fold cross …

Grape-Pi: Graph-Based Neural Networks For Enhanced Protein Identification In Proteomics Pipelines, Chunhui Gu, Seyyed Mahmood Ghasemi, Yining Cai, Johannes F Fahrmann, James P Long, Chong Wu, Jennifer B Dennison, Samir Hanash, Kim-Anh Do, Ehsan Irajizad

Faculty, Staff and Student Publications

Motivation: Protein identification via mass spectrometry (MS) is the primary method for untargeted protein detection. However, the identification process is challenging due to data complexity and the need to control false discovery rates (FDR) of protein identification. To address these challenges, we developed a graph neural network (GNN)-based model, Graph Neural Network using Protein-Protein Interaction for Enhancing Protein Identification (Grape-Pi), which is applicable to all proteomics pipelines. This model leverages protein-protein interaction (PPI) data and employs two types of message-passing layers to integrate evidence from both the target protein and its interactors, thereby improving identification accuracy.

Results: Grape-Pi achieved significant …

Exploring The Role Of Reward Functioning In The Overlap Of Post-Traumatic Stress And Cocaine Use Disorder, Kate Hull, Hanaan Bing-Canar, Krista Miloslavich, Christopher Holden, Aneet Ahluwalia, Joy M Schmitz

Faculty, Staff and Student Publications

Background: Posttraumatic stress disorder (PTSD) symptoms are common in people with cocaine use disorder (CUD), and even sub-threshold PSTD symptoms result in worse treatment outcomes. Difficulties with reward functioning may drive this comorbidity. Impairments in reward functioning are prominent in both PTSD and CUD and contribute to development of substance use problems after trauma. There are three distinct reward processes that may be involved in the PTSD/CUD overlap: consummatory reward (ability to experience pleasure), motivational reward (willingness to exert effort for rewards), and reward learning (adapting behavior based on reward history). Here we test whether impairments in these reward functions …

A Biomechanical Study Of Neck Strength And Impact Dynamics On Head And Neck Injury Parameters, Rahid Zaman, Mohammad Ibrahim Hossain, Ahmed Zubayer Raiyan, Shuvo Chowdhury, Aaron Jackson, Ashfaq Adnan

Faculty, Staff and Student Publications

Introduction: Head and neck injuries, including traumatic brain injuries (TBI), are a leading cause of disability and death worldwide. It affects millions of people worldwide, from automobiles to sports to military personnel. This study investigates the influence of impact locations, severities, and neck strength on head and neck injury parameters using a musculoskeletal head-neck model in OpenSim software.

Methods: We hypothesize that eccentric impacts, particularly those on the anterolateral side, increase GAMBIT and Neck Injury Criteria (NIC) due to elevated rotational accelerations, and that higher neck strength mitigates GAMBIT and NIC under these impacts. To test our hypotheses, we investigated …

Prrx1 Has Functional Roles In Pancreatic Acinar To Ductal Metaplasia And Carcinogenesis, Noriyuki Nishiwaki, Kensuke Sugiura, Kensuke Suzuki, Alina L Li, Constanza Tapia Contreras, Alice E Shin, Jun Zhao, Anirban Maitra, Jason R Pitarresi, Peter A Sims, Rohit Chandwani, Anil K Rustgi

Faculty, Staff and Student Publications

No abstract provided.

Individualized Frequency And Montage Tacs To Engage Theta-Gamma Coupling And Enhance Working Memory In Mild Cognitive Impairment, Mina Mirjalili, Iryna S Palamarchuk, Heather Brooks, Reza Zomorrodi, Ashley Melichercik, Sean M Nestor, Abhishek Datta, Christopher Bowie, Bernadette Mdawar, Kullervo Hynynen, Sanjeev Kumar, Tarek K Rajji

Faculty, Staff and Student Publications

Mild Cognitive Impairment (MCI) is a clinical prodromal stage of Alzheimer's disease. Enhancing executive functions in patients with MCI could optimize cognitive compensatory mechanisms and slow cognitive decline. The prefrontal cortex (PFC) and its connections to the hippocampus support executive functions, including working memory. Transcranial alternating current stimulation (tACS) can modulate these connections by engaging theta-gamma coupling (TGC) and may thereby strengthen working memory. This study, "tACS to engage theta-gamma coupling and enhance working memory in MCI" (tACS-MCI), will assess the feasibility and cognitive effects of EEG and MRI-guided individualized tACS. The stimulation will target the prefrontal and temporal cortices …

Three-Year Outcomes After Temperature-Controlled Radiofrequency Treatment Of Nasal Airway Obstruction, Curtis D Johnson

Faculty, Staff and Student Publications

Objective: To evaluate the long-term safety and effectiveness of temperature-controlled radiofrequency (TCRF) treatment of nasal valve collapse (NVC) in patients with nasal airway obstruction (NAO).

Study design: This is an extended follow-up from a prospective, multicenter, single-arm study. The initial study included participants from 12 sites across the United States who were followed for 24 months and additionally agreed to participate in the extended 36-month follow-up.

Setting: Procedure was performed in-office with an in-person follow-up at 3 months and subsequent follow-up assessment remotely.

Methods: Participants received TCRF treatment of only the nasal valve and participated in the extended 36-month follow-up. …

Advanced Method For The In Vivo Measurements Of Lysophospholipid Translocation Across The Inner (Cytoplasmic) Membrane Of Escherichia Coli

Faculty, Staff and Student Publications

Phospholipid translocation occurs ubiquitously in biological membranes and primarily is protein catalyzed. Lipid flippases mediate the net translocation of specific phospholipids from one leaflet of a membrane to the other. In the inner (cytoplasmic) membrane (IM) of Gram-negative bacteria, lysophospholipid translocase (LplT) and cytosolic bifunctional acyl-acyl carrier protein (ACP) synthetase/2-acylglycerolphosphoethanolamine acyltransferase (Aas) form a glycerophospholipid regeneration system, which is capable of facilitating rapid retrograde translocation of lyso forms of phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and cardiolipin (CL) but not exogenous (host-derived) phosphatidylcholine (PC) across the IM of Gram-negative diderm (two-membraned) bacteria in consequential order lyso-PE = lyso-PG > > lysophosphatidic acid (lyso-PA) >> lyso-PC. …

Quantitatively Assessing The Impact Of The Quality Of Snomed Ct Subtype Hierarchy On Cohort Queries, Rashmie Abeysinghe, Cui Tao, Kirk Roberts, Guo-Qiang Zhang, Licong Cui

Faculty, Staff and Student Publications

Objective: SNOMED CT provides a standardized terminology for clinical concepts, allowing cohort queries over heterogeneous clinical data including Electronic Health Records (EHRs). While it is intuitive that missing and inaccurate subtype (or is-a) relations in SNOMED CT reduce the recall and precision of cohort queries, the extent of these impacts has not been formally assessed. This study fills this gap by developing quantitative metrics to measure these impacts and performing statistical analysis on their significance.

Material and methods: We used the Optum de-identified COVID-19 Electronic Health Record dataset. We defined micro-averaged and macro-averaged recall and precision metrics to assess the …

Single-Cell Multiome Characterizing Intercellular Communication And Intracellular Regulation Of Epithelium And Mesenchymal During Secondary Palate Development In Mice, Fangfang Yan, Lukas M Simon, Zhongming Zhao

Faculty, Staff and Student Publications

Cell-cell communication between adjacent tissues is fundamental to orchestrating organ morphogenesis. During secondary palate development, interactions between epithelial and mesenchymal cells regulate epithelial-mesenchymal signaling, thereby controlling cell proliferation, differentiation, and tissue patterning. However, the precise molecular mechanisms underlying these interactions remain largely unexplored. In this study, we employed single-cell multiome sequencing to simultaneously profile chromatin accessibility and gene expression in 35,150 individual cells isolated from the developing mouse secondary palate at embryonic days E12.5, E13.5, E14.0, and E14.5. Our analysis revealed that intercellular signaling plays a pivotal role in directing secondary palate morphogenesis, with WNT, BMP, and PDGF pathways emerging …

A Data-Driven Approach To Offshore Wind Forecasting In The Celtic Sea, Ajit C Pillai, Peter Jenkin, Ian Ashton, Edward Steele, Marcus Juniper, Jiaxin Chen

School of Engineering, Computing and Mathematics

Accurate weather forecasting is crucial for various industries,including offshore wind, which is vital for global net zeroenergy goals. Machine learning models, trained on historicaldata, offer a new opportunity by replacing traditional physicsbasedequations. These models can learn patterns not alwaysrepresented by physical equations, potentially increasing the accuracyand efficiency of weather forecasting compared to traditionalNumerical Weather Prediction (NWP).This study applies a machine learning framework (MaLCOM)to offshore wind forecasting in the Celtic Sea. It uses anattention-based LSTM recurrent neural network to learn temporalpatterns and a random forest-based spatial nowcasting model,trained on ERA5 data, for spatiotemporal predictions. Windsderived from wave spectra measured by buoys …

Ecotoxicological Effects Of Sunscreen Derived Organic And Inorganic Uv Filters On Marine Organisms: A Critical Review, Anneliese A. Hodge, Frances E. Hopkins, Mahasweta Saha, Awadhesh N. Jha

School of Biological and Marine Sciences

Sunscreens are topical personal care products that provide protection against the sun's ultraviolet A (UVA) and ultraviolet B (UVB) radiation. Ultraviolet (UV) filters are compounds added to sunscreens to block, absorb, or reflect the sun's UV rays, but are of major emerging concern due to their widespread use and global distribution. They pose a significant risk to marine organisms owing to their chemical properties, including high lipophilicity which increases their bioavailability. The present review identifies and summarises the factors that contribute to UV filter pollution, their sources, pathways, and effects on marine organisms. We identify and evaluate the current knowledge …

Surfing Towards Shared Futures - Comparative Insights From Australia's World Surfing Reserves: Part Of The Series: Transformative Ocean Governance In Australia’S World Surfing Reserves - A Community-Centred Perspective, Kizzy Beaumont

School of Biological and Marine Sciences

Executive summaryThis comparative report brings together insights from the Noosa, Gold Coast, and Manly-Freshwater World Surfing Reserves (WSRs), showing how locally led stewardship delivers cultural, environmental, and economic value for coastal communities. Using a Transformative Ocean Governance lens, the analysis synthesises participant perspectives from focus groups and interviews alongside a desk-based review of official materials. Across the three sites there is clear commitment to surf culture, environmental care, and participation, with practical innovations already visible in education, etiquette, and community engagement.The sites follow different but complementary governance paths. Noosa demonstrates how independent stewardship can sit alongside council activity and deliver …

Temperature-Driven Plasticity In Boldness, Its Predictability And Learning In The Beadlet Anemone, Actinia Equina, Samantha Simpson, Dunia Gonzales, Mark Briffa

School of Biological and Marine Sciences

Variation in ambient temperature is for poikilothermic animals a key driver of behavioural variation because of its multiplicative effects on metabolic rate. Apart from the fundamental environmental source of behavioural variation, understanding the effects of temperature is also important in the context of predicted climate change scenarios. In particular, behavioural responses to extreme temperature fluctuation could represent maladaptive responses to rapidly changing environments. However, behavioural responses to moderate temperature fluctuations, within ranges that are routinely experienced, likely represent adaptive plasticity. Recent studies have addressed this question within an animal personality framework, which can quantify the effects of temperature regime across …

An Investigation Of The Biogeochemical Exchange Of The Macro Plant Nutrients Phosphorus And Nitrogen On Rewetted Peat Soil On The Somerset Levels And Moors., Natasha Underwood

School of Geography, Earth and Environmental Sciences Theses

Phosphorus, an essential nutrient for life, excess phosphorus is a common ecological concern in watercourses worldwide leading to eutrophication and pollution of natural water systems. In the UK, eutrophication of freshwater systems is one of the most common cause of water bodies not achieving good ecological status by the Environment Agency. The Somerset Levels and Moors (SLMs) condition status is described, by Natural England and the Environmental Agency, as ‘unfavourable declining’ due to the phosphate levels being up to three times higher than the Common Standards Monitoring Guidance targets of 0.1 mg/l total phosphate. Housing development on the SLMs has …

Characterization And Photodegradation Of Isolated Chemical Classes From Crude Oil., Alex Mead

School of Geography, Earth and Environmental Sciences Theses

Compounds in crude oil are photoactive and can be toxic to marine ecosystems. However, chemical characterisation of crude oil poses a significant analytical challenge owing to its complexity. This challenge is further exacerbated by the photodegradation of crude oils in the environment. The aim of the work herein was to first isolate and characterise targeted fractions from crude oil and then assess the fractions after photodegradation, to better understand the composition of crude oil and photochemical transformation of individual chemical classes.Isolation of target fractions was achieved by validating a solid phase extraction (SPE) method using ion exchange SPE to fractionate …

Metaphors And Myths: Using The Board Game Dixit To Understand The Autistic Lived Experience, Gray Atherton, Emily Dawson, Liam Cross

School of Psychology

Autism is a condition that takes on many meanings, particularly to those with lived experience. Exploring these meanings is paramount to being able to improve the way that autistic people are treated in the wider world. To further examine autistic lived experience, a new form of qualitative analysis was developed in line with the growing trend of gamification, or creating a game-like condition for exploring different domains. In this paper, we present Dixit-elicitation, a form of qualitative inquiry that uses the popular board game Dixit to interview autistic people about their experiences living with the condition. Themes and subthemes relating …

A Preliminary Study On The Role Of Personal History Of Infectious And Parasitic Diseases On Self-Reported Health Across Countries, Gerit Pfuhl, Filipe Prazeres, Marta Kowal, Toivo Aavik, Beatriz Abad-Villaverde, Reza Afhami, Leonardo Aguilar, Grace Akello, Laith Al-Shawaf, Jan Antfolk, Chiemezie S. Atama, Derya Atamturk Duyar, Roberto Baiocco, Sercan Balım, Carlota Batres, Yakhlef Belkacem, Théo Besson, Adam Bode, Merve Boğa, Jordane Boudesseul, Mahmoud Boussena, Hamdaoui Brahim, Nana Burduli, Ali R. Can, Hakan Cetinkaya, Antonio Chirumbolo, Dimitri Chubinidze, Clément Cornec, Bojana M. Dinić, Seda Dural

School of Psychology

Objectives: Infectious diseases are often associated with decline in quality of life. The aim of this study is to analyze the relationship between personal history of communicable, i.e., infectious and parasitic diseases and self-rated health. Study design: Secondary analysis of a large dataset multi-country observational study. Methods: We used a four-pronged analysis approach to investigate whether personal history of infectious and parasitic diseases is related to self-reported health, measured with a single item. Results: Three of the four analyses found a small positive effect on self-reported health among those reporting a history of pathogen exposure. The meta-analysis found no support …

Measuring Variation In Gaze Following Across Communities, Ages, And Individuals: A Showcase Of Tango-Cc (Task For Assessing Individual Differences In Gaze Understanding-Open-Cross-Cultural), Julia Christin Prein, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Umay Sen, Katie Slocombe, Robert Z. Sparks, Roman Stengelin, Jahnavi Sunderarajan, Kirsten Sutherland, Florence Tusiime, Wilson Vieira, Zhen Zhang, Yufei Zong, Daniel B.M. Haun, Manuel Bohn

School of Psychology

Cross-cultural studies are crucial for investigating the cultural variability and universality of cognitive developmental processes. However, cross-cultural assessment tools in cognition across languages and communities are limited. In this article, we describe a gaze-following task designed to measure basic social cognition across individuals, ages, and communities (the Task for Assessing iNdividual differences in Gaze understanding-Open-Cross-Cultural; TANGO-CC). The task was developed and psychometrically assessed in one cultural setting and, with input of local collaborators, adapted for cross-cultural data collection. Minimal language demands and the web-app implementation allow fast and easy contextual adaptations to each community. TANGO-CC captures individual- and community-level variation …

Nature Contact And Health Risk Behaviours: Results From An 18 Country Study, Leanne Martin, Mathew P. White, Sabine Pahl, Jon May

School of Psychology

Emerging evidence suggests that residential greenspace is associated with a lower prevalence of health risk behaviours, but it remains unclear whether these effects are generalizable across countries or different types of nature contact. Using representative cross-sectional samples from 18 countries/regions, we examined the associations between two types of nature contact (greenspace, nature visits), current smoking and everyday drinking. After controlling for a range of covariates, greenspace was inversely associated with current smoking and everyday drinking. Visiting natural spaces at least once a week was linked to a lower prevalence of current smoking, but unrelated to everyday drinking. Increasing residential greenspace …

Interventions For Promoting Physical Activity In People With Newly Diagnosed Parkinson’S Disease: Scoping Review, Jonathan Gilby, Bridie Kent, Rachel Knight Lozano, Jonathan Marsden

School of Health Professions

Background: There is increasing evidence to suggest that physical activity can slow Parkinson’s progression. There is also increasing interest in non-pharmacological interventions to alleviate Parkinson’s symptoms. This scoping review aimed to map and describe the evidence for interventions that promote physical activity in people with newly diagnosed Parkinson’s. Methods: Studies conducted since 2011, on adults with Parkinson’s (≥ 18 years), investigating the effects of non-pharmacological interventions to promote physical activity and/or exercise were considered. Interventions needed to be conducted in healthcare or healthcare-related settings for people within 5 years of Parkinson’s diagnosis. Published or unpublished full-text articles since 2011 were …

The Use Of Tele-Music Interventions In Supportive Cancer Care: A Systematic Review, Lore Mertens, Laura Tack, Tom Boterberg, Jörg Fachner, Leonardo Muller-Rodriguez, Marte Vandeweyer, Sofie Demasure, Marianne Hanssens, Tine Loyson, Laurence Goethals, Isabelle Kindts, Hannelore Denys, Patricia Schofield, Mohammad Najlah, Philip R. Debruyne

School of Nursing and Midwifery

Objectives: This systematic review seeks to provide an in-depth overview of current research on tele-music interventions in supportive cancer care and identifies key areas where further research is warranted. Methods: A comprehensive search was conducted across four electronic databases (Scopus, Embase, Web of Science, and PubMed) without any data restrictions and according to the PRISMA guidelines. The primary outcome measure was the effect of tele-music interventions on psychosocial functioning. Results: Of the 2.043 articles initially identified, nine studies met the inclusion criteria and were selected for qualitative analysis. Among the music interventions, considerable variation was observed regarding delivery format and …