Digital Commons Network^™

Eeg-Based Multi-Scale Perturbed Brain Cognitive Pattern Recognition Network For Gamer Level Classification, Lijun Jiang, Yanping Chen, Kexuan Liu, Xingyuan Chen, Li Dong, Weiya Ma, Diankun Gong, Dezhong Yao

General Human Environmental Sciences Faculty Publications and Presentations

Electroencephalogram (EEG)-based classification of video game experts versus amateurs reveals cognitive brain patterns underlying complex abilities, with applications in attention modulation, medical rehabilitation, and health monitoring. While deep learning has advanced EEG-based cognitive state detection, challenges remain in extracting meaningful patterns from noisy data and preventing reverse inference attacks on user privacy. Here, we propose a novel multi-scale perturbed brain cognitive pattern recognition network (MsPE). Its key contributions are: (1) a multi-scale weak encryption method with attention mechanisms that protects privacy by perturbing EEG signals in temporal and frequency domains; (2) ConvFormer modules with adaptive channel sizes (3, 5, 15) …

Clinical Criteria For Limbic-Predominant Age-Related Tdp-43 Encephalopathy, David A. Wolk, Peter T. Nelson, Liana Apostolova, Konstantinos Arfanakis, Patricia A. Boyle, Cynthia M. Carlsson, Nick Corriveau-Lecavalier, Penny Dacks, Bradford C. Dickerson, Gladys E. Maestre

School of Medicine Publications

Limbic predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is highly prevalent in late life and a common co-pathology with Alzheimer's disease neuropathologic change (ADNC). LATE-NC is a slowly progressive, amnestic clinical syndrome. Alternatively, when present with ADNC, LATE-NC is associated with a more rapid course. With the emergence of anti-amyloid therapeutics, discrimination of LATE-NC from ADNC is critical and will lead to greater clinical recognition of amnestic patients without ADNC. Furthermore, co-pathology with LATE-NC may influence outcomes of these therapeutics. Thus there is a need to identify patients during life with likely LATE-NC. We propose criteria for clinical diagnosis of …

Large‐Vessel Occlusion Stroke Knowledge And Training For Stroke Severity Assessment Among Emergency Medical Services Personnel In The United States, Kaiz S. Asif, Robin Novakovic, Thanh N. Nguyen, Santiago Ortega‐Gutierrez, Youngran Kim, Amanda Jagolino‐Cole, Sushanth Aroor, Alicia Castonguay, Prateek Kumar, Ameer E. Hassan

School of Medicine Publications

Background

Prehospital identification of large‐vessel occlusion (LVO) stroke facilitates the development of a regional triage protocol that could lead to an improvement in intrahospital and interhospital workflows. This requires stroke education of emergency medical services (EMS) personnel to improve stroke recognition, severity assessment, and prenotification. However, the current state of EMS personnel's knowledge of LVO stroke, their training for stroke severity assessment, and their preferences for educational methods are unknown. We conducted a nationwide EMS survey across the United States to glean insights that can inform and customize future EMS educational efforts.

Methods

The Society of Vascular and Interventional Neurology, …

Integrated Multi-Omics Analyses Of Synaptosomes Revealed Synapse-Associated Novel Targets In Alzheimer’S Disease, Subodh Kumar, Enrique Ramos, Axel Hidalgo, Daniela Rodarte, Bhupender Sharma, Melissa M. Torres, Davin Devara, Shrikanth Gadad

School of Medicine Publications

Synapse dysfunction is an early event in Alzheimer’s disease (AD) caused by various factors, including amyloid beta, p-tau, inflammation, and aging. However, the precise molecular mechanism underlying synapse dysfunction in AD remains largely unknown. To understand this, we comprehensively analyzed the synaptosomes fraction in post-mortem brain samples from AD patients and cognitively normal individuals. We conducted high-throughput transcriptomic analyses to identify changes in microRNA (miRNA) and mRNA levels in synaptosomes extracted from the brains of unaffected individuals and those with AD. Additionally, we performed mass spectrometry analysis of synaptosomal proteins in the same sample group. These analyses revealed significant differences …

2025 Viewbook, Office Of Admissions

Viewbook

At IMSA, you will be part of a community of over 650 diverse students passionate about learning. Located in suburban Aurora, IMSA’s campus consists of seven residence halls spread across 97 acres. While living and learning on campus, you’ll make new friends, encounter new ideas, and learn to live independently. You will also have the opportunity to explore over 85 clubs, organizations, and IHSAsponsored co-curricular and athletic programs. IMSA provides a safe, nurturing environment. Professional Resident Counselors (RCs) live in each hall and will help you navigate your home away from home through the Residential Life Curriculum. Through this curriculum, …

Love Is Dead In The Restless West: Hippies, Manson, And California Culture, 1966-1970, Rebecca Allen

Scripps Senior Theses

Though an extreme aberration from most of the hippie counterculture of the 1960s, Charles Manson’s ultimately murderous cult arguably represents something particular about American culture in the late sixties, in which youthful hostility towards the status quo sometimes grew radical, and in the case of the Manson Family cult, extremely violent. By the mid-sixties, more and more young people began to feel alienated by a culture they felt no longer embodied their larger aspirations, and as a result, were drawn to the emerging counterculture that embraced alternative lifestyles that frequently clashed with the traditional sensibilities of their parents’ generation. After …

The Effect Of Regime Type On Development Outcomes In Bangladesh, Simar Malhotra

Scripps Senior Theses

Bangladesh has been characterized by a turbulent political state since gaining its independence in 1971, moving back and forth between a democracy and autocracy. With this, they have also experienced immense gains in development over the last thirty years, especially within health, education, and female empowerment. This thesis exploits Bangladesh’s unique regime-switching setting to measure the impact of a shift from autocracy to democracy on child health, maternal health, and women’s autonomy within a single-country context. Using data from the Demographic and Health Surveys (DHS) Program, the analysis finds that a shift from an autocracy to a democracy increases the …

The Moral Justifications Of The Justice-Experienced: Recidivism In Dark Triadic Morally Disengaging Offenders, Lacy Parrett

Scripps Senior Theses

Little is known about the cognitions of those who commit violent crimes; even less is known about the justification process of those who reoffend after completing a prison sentence. The proposed study suggests analyzing the moral disengagement strategies and personality traits of incarcerated adults to identify recidivism risk factors. Current literature indicates that nonhomicide violent offenders’ use of moral disengagement cognitions that justify the violation of socially accepted morals will moderate the relationship between psychopathic, Machiavellian, and narcissistic personality traits and offenders’ risks of recidivating. Furthermore, it is anticipated that an interaction will exist between moral disengagement and this so-called …

Empowering Adolescent Females: A Psychological Approach To Sexual Education, Paola Rausseo

Scripps Senior Theses

Adolescence is a pivotal stage of self-discovery, yet many young women lack the tools and knowledge to navigate sexual health confidently. This study implements an intervention rooted in Cognitive Behavioral Therapy (CBT) and Social Learning Theory (SLT) to enhance empowerment, self-advocacy, and boundary-setting in adolescent females aged 13–16. The program’s structure incorporates skill-based activities, including role-playing and action planning, to equip participants with practical tools and a safe space to practice these skills. This approach emphasizes addressing psychological and social factors influencing sexual decision-making and seeks to bridge gaps in traditional sexual education. Participants will be recruited from six randomly …

Cashing In Or Giving Back: The Role Of Film Tax Incentives In The Cultural Impact Of Runaway Productions, Karolina Krok

Scripps Senior Theses

This thesis explores the internationalization of Hollywood through economic and creative runaway productions driven by international tax incentives. It examines how these incentives can impact not only the commercial but the cultural success of productions filmed abroad, focusing on regions such as Australia, New Zealand, Canada, the United Kingdom, France, Germany, California, New York, and New Jersey. The analysis centers on cultural tests and diversity requirements, revealing two main approaches: the first requires a minimum of diversity standards and cultural tests points to be met, while the second prioritizes and rewards productions with the highest achieved assessment of those. Furthermore, …

In It For The Long Haul: Long-Haul Trucking And The American Myth, Ava Flum

Scripps Senior Theses

In It for the Long Haul: Long-Haul Trucking and the American Myth explores the intersection of culture, economics, and politics in the world of trucking, using the freight industry as a case study to interrogate the promises and failures of the American Dream. This thesis examines how the myth of trucking—framed as a pathway to freedom, prosperity, and autonomy—collides with the lived realities of truck drivers, who face economic precarity, corporate exploitation, and intense personal sacrifice.

Through an analysis of deregulation, industry practices, and the persistence of the myth in public consciousness, this work exposes how the romanticized ideals of …

Characterization Of Dietary And Hormonal Influences On Renal Sodium Transporters And Channels In Rodent Models, Evelyn Chan

Scripps Senior Theses

Within kidneys, a diverse array of renal epithelial cells works to maintain electrolyte and water balance to regulate blood pressure and pH. These cells contain varying types of sodium transporters that adjust sodium reabsorption according to the body’s needs. Previous studies have observed sex-specific differences in renal sodium transporter regulation, which are thought to optimize reproduction in females. In this study, we performed high resolution microscopy and detailed characterization of cell type-specific expression and localization of major sodium transporters and channels in rodents in response to dietary and hormonal influences. Specifically, we examined the impact of dietary salt intake and …

The Association Between Obstetric Violence And Postpartum Depression Among Latina Women In The United States: An Integrative Review, Natalia Alameda

Scripps Senior Theses

Obstetric violence, a structural form of gender-based violence, involves abuse, mistreatment, or neglect by healthcare providers during obstetric care. It is often associated with childbirth trauma and may result in physical and psychological harm to mothers and children, including postpartum depression. Postpartum depression is a major depressive episode occurring during pregnancy or within four weeks following delivery. While these concepts are often studied independently, few studies examine their intersection, particularly among Latina women in the United States. To address this gap, an integrative literature review was conducted to explore the association between obstetric violence and postpartum depression among Latina women. …

Let's Talk About Sex: Investigating Radical Feminist Theories On Prostitution In The United States, Anna E. Peterson

Scripps Senior Theses

This paper explores the feminist debates surrounding prostitution through an analysis of Catharine MacKinnon and Andrea Dworkin’s abolitionist theories, juxtaposed with critiques from Wendy Brown, Janet Halley, Susie Bright, and Marxist feminist abolitionist Esperanza Fonseca. The text examines the systemic forces of patriarchy and capitalism that commodify women’s bodies and the challenges of legislative approaches to the sex trade. While MacKinnon and Dworkin identify the structural inequalities underpinning prostitution, their legislative proposals often fail to address the stigma and systemic conditions that perpetuate the marginalization of prostituted people. Critics like Brown and Halley highlight the limitations of punitive measures, calling …

El Maíz Del Abuelo: Fidel Márquez Sanchez’S Legacy And Mexico’S Historical Maize Agriculture, Lucia Marquez-Uppman

Scripps Senior Theses

The Green Revolution was an era of scientific development in productive agricultural methods and technologies in the mid-twentieth century. High-yielding seed varieties, artificial fertilizers, irrigation infrastructure, pesticides, and herbicides all developed from this period. Texcoco, Mexico was the center of much of the Green Revolution's education and research from the 1940s onward at the Autonomous University of Chapingo, a prestigious agricultural school, with funding from the US-based philanthropic Rockefeller Foundation. Powerful consequences in the globe's agriculture emerged from the Green Revolution, including the production of maize, a staple crop in Mexico, especially for Indigenous and campesino populations. My abuelo, Fidel …

Sense Of Belonging And Perceptions Of Learning In An Introductory College Course, Ellen Wang

Scripps Senior Theses

A sense of belonging (SB) – the feeling of deep connection with social groups, places, and experiences – has been described as a fundamental, pervasive need among humans (Allen et al., 2021; Baumeister & Leary, 1995). SB, and lack thereof, predicts myriad mental, physical, social, and economic outcomes. Belonging is a complex, multidimensional concept with a breadth of research across disciplines. It has been applied to school contexts in association with academic and psychosocial outcomes. The researcher partnered with an undergraduate course at The Claremont Colleges, and administered electronic surveys at two time points of the course. Students' sense of …

Garcia De Orta And The Colloquies: The Role Of Imperialism And Colonialism In Shaping Knowledge During The Scientific Revolution, Anabhra Singh

Scripps Senior Theses

This thesis examines the role of Portuguese doctor Garcia de Orta (1501–1568) and his Colloquies on the Simples and Drugs of India within the broader framework of the Scientific Revolution, emphasizing the interplay of imperialism, colonialism, and transnational knowledge exchanges in shaping knowledge production. Traditional narratives of the Scientific Revolution often focus on European advancements in physics and astronomy. However, recent scholarship highlights the contributions of non-European knowledge systems and the significant role of empire and trade networks in advancing scientific inquiry. Although Orta’s findings were not novel, the novelty of his text lay in its seamless integration of European, …

Bright-Lines In Sentencing: A Legal And Moral Case Against Juvenile Life-Without-Parole, Mckenzie Reily Isaac

Scripps Senior Theses

This paper criticizes the Supreme Court of the United States for its holding in Jones v. Mississippi (2021): the Eighth Amendment does not require a sentencing authority to find that a juvenile is "permanently incorrigible" before it may impose a sentence of life-without-parole. This ruling circumvents stare decisis as it undermines the substantive protections established in Miller v. Alabama (2012) and Montgomery v. Louisiana (2016), while purporting to preserve them. Not only is circumvention of stare decisis a failure of the Court's judicial duty, it is also a profound moral failure. This paper deploys Ronald Dworkin's law as integrity to …

Social Rejection, Isolation, And Substance Use Disorders: A Neurobiological Defense Of Social Network Intervention In Single-Site Housing First, Victoria Eichel

Scripps Senior Theses

Abstract

Introduction: Rising rates of homelessness in the United States demand not only increased housing efforts but also comprehensive strategies addressing the underlying causes of chronic homelessness. Among the most prevalent factors is substance use disorder (SUD), which both contributes to and results from housing instability. Conventional abstinence-based treatment models often fail to address the root causes of substance use, particularly the chronic social isolation and rejection experienced by the unhoused. This thesis argues for the adoption of a neuroscience-informed model of recovery rooted in community reintegration and low-barrier housing with on-site support services.

The Neuroscience of Substance Use Disorders …

"Girl, So Confusing": Tiktok Tweens, Technology, And The Authentic Self, Emily R. Dietrick

Scripps Senior Theses

This thesis examines the American tween as a postfeminist subject within the context of youth cultural production on TikTok, responding to the recent resurgence of concern about the young girls’ body in popular discourse. The first chapter will explore the origins of the tween as the marketing industry category previously known as the subteen, particularly through the lens of tween media culture and postfeminist narratives of choice and authenticity in identity formation. The second chapter will analyze the current technological facets of TikTok with attention to the For You page, algorithm, user-generated content, and influencer self-branding. This will demonstrate how …

Medicare Drug Price Negotiations: A Blueprint For Ethical Pricing Across The Healthcare System, Jacqueline Fox

FIU Law Review

In a healthcare system with scarce resources, profit that exceeds the value of what is being paid for cries out for justifications. The Medicare Drug Price Negotiation Program, created by the Inflation Reduction Act of 2022, is a new program that allows Medicare to begin negotiating with drug companies to determine the maximum fair price for a small set of drugs. This Article argues that the methods for conducting these negotiations represent a significant step forward in a dramatic and important reordering of how we view the healthcare financing system, allowing us to consider rational, coherent concepts of value without …

Publisher

FIU Law Review

No abstract provided.

Dei And Antisemitism: Bred In The Bone, Suzanna Sherry

FIU Law Review

The article explains why no one should have been surprised by the antisemitism that exploded on college campuses after October 7, 2023. The article demonstrates that the worldview espoused by the DEI (diversity, equity, and inclusion) movement -- and its cousins, antiracism and wokeness -- is inherently and inevitably antisemitic. The antisemitism "bred in the bone" of DEI was bound to come to the surface eventually, and it did.

Inflammatory Mediators And The Rage Pathway In Placental Tissues Of Pregnancies Complicated By Severe Preeclampsia, Neelima Chandra, Thomas D. Kimble, Kathleen R. Heim, Sharon M. Anderson, Andrew P. Wong, Andrea R. Thurman, Gustavo F. Doncel

CONRAD Publications

Introduction: Preeclampsia (PE) is a complex multisystem disorder of pregnancy associated with abnormal placentation, vascular anomalies, and systemic inflammation and hypertension. Previous research assessing inflammatory triggers of the condition used plasma, amniotic fluid, or explant samples. Studies using placental tissue from either vaginal or cesarean deliveries are confined to semiquantitative analysis using subjective scoring methods and generally involve a small sample size.

Methods: In this study, we have quantified the expression of inflammatory mediators by immunohistochemical image analysis of archived placental tissues obtained from cesarean delivery of preeclamptic, chorioamnionitic, and normal pregnancies.

Results: Among the inflammatory mediators, we found a …

Genetic Associations Among Inflammation, White Matter Architecture, And Extracellular Free Water, Amanda L. Rodrigue, Emma M. Knowles, Josephine Mollon, Samuel R. Mathias, Juan M. Peralta, Ana C. Leandro, Peter T. Fox, Peter Kochunov, Rene L. Olvera, Laura Almasy, Joanne E. Curran, John Blangero, David C. Glahn

School of Medicine Publications

Phenotypic and genetic relationships between white matter microstructure (i.e., fractional anisotropy [FA]) and peripheral inflammatory responses (i.e., circulating cytokines) have important implications for health and disease. However, it is unclear whether previously discovered genetic correlations between the two traits are due to tissue‐specific white matter architecture or increased free water in the extracellular space. We applied a two‐compartment model to diffusion tensor imaging (DTI) data and estimated tissue‐specific white matter microstructure (FAT) and free water volume (FW). We then quantified their heritability and their genetic correlations with two peripherally circulating proinflammatory cytokines (IL‐8 and TNFα), and compared these correlations to …

Punishing Violence, Shima Baradaran Baughman

American University Law Review

The American criminal justice system doles out the harshest punishments in the world. It is infamous for its protracted criminal sentences and prodigious criminal code. But what most scholars and policymakers overlook is that the United States punishes only a fraction of the total serious crime that occurs in the country—including violent crime.

Approximately twenty million serious crimes occur in America each year, but only about half of these are reported to police. Of those reported, the police make arrests for an average of only twenty percent of serious crimes, and only ten percent of arrests result in a conviction. …

Arbitrator Selection Default Rules, Irene M. Ten Cate

American University Law Review

This Article makes the case for changing the default settings for the selection of arbitrators in international commercial arbitration. For three-member tribunals, the rules of most international arbitration institutions provide that each party picks an arbitrator. The institution or the co-arbitrators then select the tribunal’s president. This prescription, which parties may set aside by agreement, codifies longstanding practices and corresponds to the strong preference of international arbitration insiders. Nonetheless, I argue that arbitration rules should default toward institutional selection of all arbitrators.

Switching the default nudges parties that can’t take full advantage of the arbitrator selection game—due to inexperience, lack …

Shrines Of Discrimination: A Comparative Exploration Of American And Indian Approaches To Balancing Religious Freedom And Equal Rights, Sree Vedala

MC Law Review

Religious freedom and equality, foundational human rights, often clash in legal contexts, particularly when religious practices justify discriminatory actions. The U.S. judiciary has grappled with this tension, as exemplified in Masterpiece Cakeshop v. Colorado Civil Rights Commission and Yeshiva University v. YU Pride Alliance. These cases reflect opposing judicial tendencies: deference to religious beliefs versus prioritization of equality. However, neither case established a clear framework for balancing these rights. This article examines India’s "essentiality test," which assesses whether a religious practice is integral to a faith, as a potential model for resolving such conflicts. By comparing U.S. and Indian …

Amending Rule 15.3 Of The Mississippi Rules Of Criminal Procedure To Fully Capture Boykin V. Alabama And Acknowledge Systemic Coercion Indigent Defendants Face In Mississippi, Sarina P. Larson

MC Law Review

The U.S. Constitution—not a state—is what governs questions of constitutionality. It follows that for a state court to make a constitutionally sufficient record of a defendant’s waiver at their plea, the complete interpretation as to sufficiency by the United States Supreme Court must be followed. This Comment stands for the proposition that when Rule 15.3 of the Mississippi Rule of Criminal Procedure was adopted in 2017, it misinterpreted the call of the United States Supreme Court in Boykin v. Alabama, 395 U.S. 238 (1969). Ultimately, this Comment suggests amendments to Rule 15.3 that would place it in compliance with Boykin, …

Ai-Driven Smart Contract Vulnerability Detection: A Systematic Review Of Methods, Challenges, And Future Prospects, Saad Al Azzam, Raenu Al Kolandaisamy, Ghassan Al Dharhani

Mesopotamian Journal of Big Data

Smart contracts (SCs) have become an essential component in the world of decentralized applications, automating transactions across blockchain networks without the need for intermediaries, and with this rise in adoption, the technology has also brought forth growing concern due to security vulnerabilities, which have led to serious financial damage, and the problem is far from being solved. Traditional auditing methods often struggle to capture the more intricate vulnerabilities hidden within smart contract logic, particularly owing to the irreversible nature of blockchain transactions. Given these challenges, researchers have been actively exploring more advanced detection techniques. Despite progress, many existing studies tend …