Digital Commons Network^™

Using The High Resolution Rapid Refresh To Validate A Novel Forecast Methodology, Sylvia M. Garmong

Electronic Theses & Dissertations (2024 - present)

NOAA’s High-Resolution Rapid Refresh (HRRR) is frequently used by forecasters for short term predictions and although the model performs well in many metrics, previous study (Fovell and Gallagher 2020) identified temperature and windspeed biases within the boundary layer using radiosonde and surface observations. The current work uses a forecast drift metric to study how model forecasts evolve with time and distance to radiosonde sites. The metric is calculated by subtracting model analysis from forecasts at the same valid time, creating a proxy for bias. HRRR data on native model levels are obtained from the Google Cloud and Amazon Web Services …

Deep Convection, Lightning, And Inertio-Gravity Waves: An Analysis Of Precipitation And Wave Dynamics In The Congo Basin, Stephen L. Solimine

Electronic Theses & Dissertations (2024 - present)

The lack of an extensive in situ observation network throughout equatorial Africa makes it difficult to monitor the Congo climate system. Model and reanalysis products have been used to fill informational gaps but often produce disparate results. To improve model representation of deep convection over the Congo, it’s important to first understand the influence of various thermodynamic and dynamic forces that may be underrepresented. Although satellite based remote sensing retrievals and reanalysis have their own set of limitations, they can offer a great deal of insight into the climate of regions otherwise lacking in observational networks.

The first section of …

A Strength-Based Approach To Understanding The Impact Of Experiences Of Discrimination Related To Identity-Based Stressors On Disordered Eating Among A Sample Of Sexual And Gender Diverse Individuals, Susana Cruz Garcia

Electronic Theses & Dissertations (2024 - present)

Empirical research investigating eating disorder (ED) behaviors among sexual and gender minorities has grown substantially in recent decades, though notable gaps call for further work to clarify mixed findings regarding the experiences of this heterogeneous population. This study sought to add to our understanding of disordered eating behaviors in LGBTQIA+ participants, with a specific focus on differences between lesbian and gay (LG) versus bisexual, transgender, queer, intersex, asexual, and other identities (BTQIA+), with the latter group remaining especially underrepresented in the literature. Study aims were firstly, to quantify ED incidence and the frequency of experiences of identity-based discrimination in sexual …

Multimorbidity In Adolescents: The Longitudinal Impact Of Childhood Socioeconomic Trajectories And Health Risk In Adulthood, Savitha Sambandamoorthy

Electronic Theses & Dissertations (2024 - present)

Abstract

Background:

Multimorbidity, defined as the co-occurrence of two or more health conditions (physical, mental, or both), has been thought of as a disease of the elderly, with most studies of multimorbidity focusing on adults and the elderly population. However, co-occurring (multimorbid) health conditions are common in adolescence, and it is important to understand the profiles and patterns of multimorbidity during adolescence, a critical developmental period with long-term implications. Social determinants of health, especially lower socioeconomic status (SES), are linked to higher risk of multimorbidity and poor outcomes in adulthood. However, most of the past studies that have looked at …

Novel Silicon Anodes For Improved Lithium Ion Battery, Amir Hegazy

Electronic Theses & Dissertations (2024 - present)

Li-ion battery (LIB) have been dominating the development of electronics shaping our daily life owing to their good specific and volumetric energy densities. However, the technological advancement calls for higher energy, safer, lower cost, and large-scale manufacturing batteries.

Silicon is considered an excellent candidate for anode material for higher energy LIB. This thesis examines the potential of silicon as an anode in high-capacity LIBs where the role of silicon is studied at the frontside (FS) and the backside (BS) of the anode. At the frontside, the effect of deposition of silicon on graphite on the battery performance was studied. Graphite …

Can Deliberate Practice For Inner Skills Enhance Therapist Trainees’ Mindfulness And Presence When Working With Clients?, Edmund W. Orlowski Iii

Electronic Theses & Dissertations (2024 - present)

A replicated single-case design was used to assess the effectiveness of therapist trainees’ engagement in deliberate practice for inner psychotherapy skills (Rousmaniere, 2019). Deliberate practice (DP) is a structured approach to therapist skill development that involves repeatedly observing and responding to real or simulated clients (Rousmaniere, 2016). It was reasoned that by attending to their inner experience while repeatedly being exposed to challenging clinical material (e.g., a client’s suicidal ideation) outside of therapy, trainees may reduce their experiential avoidance and thus be more mindful and present in sessions with actual clients.

During the five-week baseline phase of the study, four …

Paraconsistency In Legal Systems: Why Not To Evaluate The Law With Classical Logic, Sydney Coddington

Electronic Theses & Dissertations (2024 - present)

The following paper puts forth an argument for the analysis of legal systems via paraconsistent logics instead of classical logic due to the existence of legal dialetheia - true contradictions born from the law. Given that contradictions lead to absurdity in classical logic, a paraconsistent perspective becomes the clear choice once the existence of legal dialetheia is established. The first half of this argument, therefore, aims to support the work of Graham Priest in establishing legal dialetheia by explaining his view and combatting his opponent, J.C. Beall, who finds such dialetheia to fail beyond the limited scope of a legal …

How Does Social Capital Influence The Preferences For Aging In The Community? Based On The Study Toward Older Adults In Yuexiu District, Guangzhou City, Biyun Xiang

Electronic Theses & Dissertations (2024 - present)

This study examines how social capital influences older adults’ preferences for aging in the community, focusing on Yuexiu District, Guangzhou. Using a mixed-methods approach, the study explores family, structural, and cognitive dimensions of social capital.

Quantitative data were collected through 439 surveys, with 400 valid responses from adults aged 60 and above. Regression analysis identified key predictors of aging-in-community preferences, including family financial support, care commitment, activities with grandchildren, community trust, mutual help, and service satisfaction.

Qualitative data from 10 interviews with community service workers revealed six themes: (1) access to services like fitness and health screenings; (2) levels of …

Phylogenetic Analysis Of Metabolic Enzymes In Hypoxic/Anoxic Conditions In Cetaceans And Cancer, Samerna A. Masih

Electronic Theses & Dissertations (2024 - present)

Cancer cells often exhibit a Warburg-like metabolism, which includes increased fatty acid synthesis and storage that help them survive in hypoxic conditions. This shift is marked by the heightened synthesis and accumulation of fatty acids, acting as a survival mechanism in low-oxygen environments (Baumann et al., 2016). Interestingly, deep-diving whales may utilize a similar metabolic pathway to produce wax esters during their prolonged dives.

Our study focused on exploring the genetic and metabolic similarities between breast cancer cells and deep-diving whales, using computational analyses to investigate lipid metabolism genes. We looked for evolutionarily conserved variations that might reveal adaptive mechanisms …

Issues And Challenges In Silicon Based Quantum Computing, Rafia Ayub

Electronic Theses & Dissertations (2024 - present)

Silicon-based quantum computing has emerged as a promising platform for scalable and fault-tolerant quantum information processing. This thesis investigates the use of silicon quantum dots as qubits, addressing a key limitation in their implementation—charge noise and decoherence. We explore the physical and electronic properties of silicon quantum dots, focusing on their coherence times, tunability, and compatibility with existing semiconductor fabrication technologies. Through theoretical analysis and numerical simulations, we examine the impact of material imperfections and propose strategies to mitigate decoherence effects, thereby enhancing qubit stability. Additionally, we discuss potential pathways for integrating silicon quantum dots into large-scale quantum architectures. Our …

Framing Ethnicity: How Ideological Threats Shape State Policies Towards The Ethnic Chinese In Southeast Asia, Zheng Wang

Electronic Theses & Dissertations (2024 - present)

Post-colonial multiethnic societies still face significant challenges in nation-building today. Not only do countries follow different paths in dealing with ethnic diversity, but many also shift their strategies across time. State policies towards the ethnic Chinese in Southeast Asia, including accommodation, integration, marginalization, and assimilation, vary along two dimensions: the state’s discrimination towards the ethnic Chinese and the room for negotiation between the state and the ethnic Chinese in formulating these policies. Based on puzzling empirical observations on differing levels of changes in state policies towards the ethnic Chinese in Indonesia, Malaysia, and Singapore in the 1960s and 1970s, my …

Predictors Of Viral Suppression Among People Living With Hiv (Plhiv) On Antiretroviral Treatment In Almaty, Kazakhstan, Ainur Kussainova

Electronic Theses & Dissertations (2024 - present)

ABSTRACT

Introduction

The Eastern Europe and Central Asia (EECA) region is experiencing the world’s fastest-growing HIV epidemic, with Kazakhstan among the countries most affected. Despite progress in HIV testing and treatment, Kazakhstan continues to face significant challenges in achieving optimal viral suppression among PLHIV. While 82% of PLHIV in Kazakhstan know their HIV status, only 73% are on ART, and just 67% of those on treatment achieve viral suppression. Adherence to ART remains a critical barrier, influenced by a complex interplay of individual, social, and structural factors, including mental health disorders such as depression, substance use, stigma and discrimination. Understanding …

Ribosome Hibernation In Mycobacterium Abscessus And Its Effect On Antibiotic Resistance, Ryan Treen

Electronic Theses & Dissertations (2024 - present)

Non-tuberculosis mycobacteria (NTM) represent a diverse repertoire of species, most of which are ubiquitous in the environment. Some NTM species, such as Mycobacterium abscessus, can cause life-threatening infections in people with underlying medical conditions. The clinical incidence of such infections is on the rise, posing an emerging threat to public health. M. abscessus is characterized by intrinsic and acquired antibiotic resistance, complicating treatment strategies. Most chemotherapeutic approaches for M. abscessus infection target the bacterial ribosome, necessitating a better understanding of the physiological processes which confer this resistance. Multiple mycobacterial species respond to zinc-limiting conditions by inducing remodeling and hibernation …

An Unlikely Burden, Kendall J. Aufmuth

Electronic Theses & Dissertations (2024 - present)

An Unlikely Burdening follows the story of twins, Madeline and Isaac Blake. The harrowing story explores the adversities faced by these high achieving siblings, uncovering deeper truths and depths of pain far seen from the surface. It takes place in various settings, beginning in a mental health inpatient facility after Madeline’s failed suicide attempt, uprooting the entire family’s world as they knew it. Uniquely written in diary form, it provides prospective to the reader from Madeline, Isaac, and both parent’s viewpoint as well. An Unlikely Burdening addresses real world issues such as mental health, and assault. Can Madeline overcome her …

Managing Artificial Intelligence In The Public Sector: Adoption, Implementation, And Results, Tzuhao Chen

Electronic Theses & Dissertations (2024 - present)

With the rapid advancement of artificial intelligence (AI), governments around the world are increasingly exploring how AI can enhance decision-making and improve public service delivery. A growing body of research has examined governmental use of AI, offering insights into several key areas: (1) domains of application, (2) potential benefits and risks of AI initiatives, and (3) adoption and implementation processes, including critical determinants and results. However, two significant gaps remain in the literature. First, there is limited understanding of how the unique characteristics of AI may transform government service delivery and internal operations. Second, while many studies on AI-related managerial …

Developing Concepts In Second Language (L2) Science From ‘Bits And Pieces’ Of Prior Knowledge: A Multiple Case Study Of Spanish-Speaking 4th And 5th Graders, María Isabel Martínez-Cuenca

Electronic Theses & Dissertations (2024 - present)

Earth science concepts sit at the intersection of the compounding difficulties English language learners’ (ELLs) face in content-integrated instruction. Emerging first language (L1) skills, emerging L2 language, and the difficulty of science terms interact with second language (L2) content learning. Moreover, L2 science concepts rarely develop incidentally through L2 socialization and instruction in the same naturalistic way as they do in the L1. Leveraging L1 resources may help ELLs in this process, yet there is a dearth of studies that consistently do so. This dissertation explores how, and the extent to which, leveraging ELLs’ pre-existing knowledge may support science and …

Integrable Deformations, T-Dualities And Higher Order Corrections In String Theory, Parita Shah

Electronic Theses & Dissertations (2024 - present)

This thesis explores the interplay of hidden symmetries and dualities in string theory, with a particular emphasis on the role of T-duality. As a fundamental symmetry of string theory, T-duality offers a powerful lens through which one can study integrability, solution-generating techniques, and quantum corrections, all essential aspects of modern string theoretic frameworks.

A central focus of this work is the application of the duality covariant formalism of Double Field Theory (DFT) to address problems involving integrable deformations and higher-order quantum corrections. We examine how generalized integrable models can be embedded into DFT and how the formalism captures hidden symmetries …

The Multifaceted Role Of Glutamate At Excitatory And Inhibitory Synapses, Maurice A. Petroccione

Electronic Theses & Dissertations (2024 - present)

Our thoughts, memories, and actions are finely controlled by the coordinated activity of neural circuits in the brain. Prior work has identified a multitude of molecular mechanisms that contribute to the generation of these higher order functions, yet we know very little about how our ability to learn and perform habitual actions change depending on how far neurotransmitters released from neurons can travel away from their point of release. This is the main focus of my work, which I carried out using a diverse toolbox and focusing on two brain regions: the hippocampus and the striatum. The hippocampus controls learning …

Al(X)In(Y)Ga(1−X−Y)N-Based Monolithically Integrated Ir Detector-Visible Emitter Device, Alireza Lanjani

Electronic Theses & Dissertations (2024 - present)

III-Nitride material system has been widely used in electronic, sensing, optoelectronic, and power device applications. Owing to the wide and tunable bandgap of this material system and the realization of relatively high conductivity p-type Mg-doped GaN films, considerable research over the past few decades has focused on applications based on wide bandgaps, such as blue and ultraviolet (UV) light-emitting diodes (LEDs), laser diodes, visible-blind and solar-blind photodetectors. The other side of the spectrum, infrared (IR) has remained considerably less explored.

To exploit III-Nitrides for IR detection applications, the quantum well infrared photodetector (QWIP) design is employed. In the QWIP …

Characterization Of Corticotropin Releasing Factor Receptor 2 In Stress-Regulating Regions Of The Mouse Brain, Jennifer J. Lafrican

Electronic Theses & Dissertations (2024 - present)

Sex differences in the morphology of the brain are thought to underlie the sex differences we see in anxiety and depression, where women are twice as likely to be diagnosed when compared to men. Stress, or a disruption to homeostasis, can exacerbate these mood disorders. Corticotropin releasing factor (CRF), and its receptors, play an important role in regulating the stress response. Binding of CRF with CRFR2 has been shown to reduce behavioral and neuroendocrine stress responses, yet whether there are sex differences in CRFR2 expressing neurons and stress-induced activation of these neurons in mice is unknown, in part due to …

Non-Profit Hospital Spending On Community Health Improvement: Catalysts, Impediments, And Opportunities In New York State, Isaac H. Michaels

Electronic Theses & Dissertations (2024 - present)

This dissertation assesses the distribution and determinants of spending by non-profit hospitals in New York State on community health improvement services and community benefit operations. Utilizing the Social Ecological Model of Health, this study considers multiple levels of influence on this spending, including organizational and community characteristics. Using quantitative analysis, it examines cross-sectional, spatial, and longitudinal patterns in spending and identifies organizational and community-level factors influencing it. Qualitative analysis investigates operational factors affecting spending, including individual and interpersonal influences. The results of this mixed-methods study can inform hospital administrators, public health officials, policymakers, and communities in optimizing policies and decision-making …

Polygenic Risk Scores Of Grip Strength In Men And Women With Or At Risk For Hiv, Sreevidya Sadananda Sadasiva Rao

Electronic Theses & Dissertations (2024 - present)

Background: Adequate hand function among older adults is necessary for the successful completion of activities of daily living and can affect whether an older adult is able to live independently. Current research highlights grip strength, the strength people have in their hands, as a robust predictor of morbidity and mortality, and explores the decline in grip strength over time. A person’s family history and genes (DNA) affect how much grip strength they have. Previous studies have identified genes that affect grip strength, mainly in European ancestry populations. In this study, we examined whether these genetic elements predict grip strength in …

Dna And Protein Determinants For P63 Transcriptional Activity, Abigail Mccann

Electronic Theses & Dissertations (2024 - present)

The transcription factor p63 is critical for development of the epidermis and other epithelial-related structures. Mutations in the DNA-binding domain of p63 lead to a range of human developmental disorders characterized by symptoms such as ectrodactyly, painful skin dysplasia, and cleft lip and palate. The TP63 gene is also amplified in squamous cell carcinomas, contributing to tumor pathogenesis. While the importance of p63 in human health is well established, the mechanisms underlying its control of an essential gene network remain unclear. TP63 encodes multiple isoforms with distinct N- and C-terminal domains. The ∆Np63α isoform is directly linked to epidermal development …

Essays On Innovation And Labor Market Benefits, Kyoungah Noh

Electronic Theses & Dissertations (2024 - present)

The first chapter examines the impact of bank failures on team-based innovation, focusing on the persistence of inventor teams under credit supply constraints. Using U.S. patent and FDIC data from 2000 to 2012, this paper presents three main findings. First, bank failures significantly reduce both the number of team patents and the number of inventors with collaborators. Second, negative banking shocks decrease the likelihood that inventor teams remain together for projects in subsequent periods. However, team-specific factors, including geographic proximity, prior collaboration experience, and smaller team sizes, mitigate the adverse effects of bank failures and help preserve the stability of …

Unveiling The Cell Composition Of The Olfactory Migratory Mass: Perspectives On Terminal Nerve Formation, Olfactory Development, And Migration Of The Gnrh-1 Neurons, Enrico Amato Jr.

Electronic Theses & Dissertations (2024 - present)

Puberty is a postnatal developmental process required to initiate key sexual maturation events that are necessary for the propagation of species. Signals to initiate these events first begin with the Gonadotropin releasing hormone-1 (GnRH-1) neurons within the hypothalamus. The hormone GnRH-1 released by these neurons is crucial for puberty, fertility and reproductive processes by establishing the hypothalamic-pituitary-gonadal (HPG) axis, regulating release of sex hormones (Progesterone, Estrogen, Testosterone). Conditions related to inability of the GnRH-1 neurons to correctly release GnRH-1 can lead to aberrant or delayed puberty, a condition known as hypogonadotropic hypogonadism (HH). Interestingly, some patients with the hormonal disorder …

Contactin2(Cntn2)Creert2 Mouse Line, A New Genetic Tool For Temporal Control To Trace The Developing Neurons In The Nose, Alexis M. Semon

Electronic Theses & Dissertations (2024 - present)

Neuronal migration is a vital process in embryonic development. In rodents, the very first neurons that originate from the olfactory placode migrate toward the developing brain as part of the migratory mass. This migratory mass includes Gonadotropin-releasing hormone-1 (GnRH-1) neurons, pioneer/terminal nerve (TN) neurons, and olfactory ensheathing cells—a type of glial cell.

Contactin-2 (Cntn2), also referred to as transiently expressed axonal surface glycoprotein-1 (TAG-1), belongs to the contactin family of proteins, which is part of the immunoglobulin superfamily of cell adhesion molecules. Cntn2 has been extensively utilized as a transient/stage-specific molecular marker for various neuronal populations, including commissural neurons of …

Misoscale Vortices In The Eyewall Boundary Layer Of A Tropical Cyclone In A Large Eddy Simulation, Emily A. Lucy

Electronic Theses & Dissertations (2024 - present)

Since the late 1980s, there have been numerous observations of extreme updrafts, gusts, and small-scale rotation in the eyewall of tropical cyclones (TCs). Research aircraft, dropsondes, and, more recently, mobile radars have collected these observations, most often from within the boundary layer. Previous studies have documented dropsondes associated with extreme gusts and updrafts, while others have discussed specific incidents of misoscale features in tropical cyclones. Several high-resolution numerical simulations of TCs have documented similar features. This study uses one such simulation from Worsnop et al. (2017). A small but intense tropical cyclone in a quiescent environment is simulated.

This simulation …

Epithelial Responses And Remodeling In The Submandibular Gland Post-Irradiation, Victoria Gellatly

Electronic Theses & Dissertations (2024 - present)

Radiation therapy for head and neck cancer often causes irreversible salivary gland dysfunction, resulting in chronic xerostomia. Understanding the cellular and molecular mechanisms underlying this dysfunction is essential for developing regenerative therapies. Given the cellular complexity of the salivary gland single-cell RNA sequencing (scRNA-seq) provides a powerful approach to investigate cell-type-specific injury responses to ionizing radiation (IR) and uncover transcriptional changes that may be masked in bulk analyses. This study investigates the cellular and molecular responses of the murine submandibular gland (SMG) to irradiation, with a focus on epithelial loss and remodeling, and regenerative failure. In order to effectively use …

Immersive Extended Reality For Lower Limb Rehabilitation: Design, Deployment, And Pilot Study, Jeremy Varghese

Electronic Theses & Dissertations (2024 - present)

This thesis presents the design, deployment, and pilot study of an immersive extended-reality (XR) rehabilitation system integrated with a ceiling-mounted dynamic body-weight support device (Vector Gait and Safety System), aimed at improving lower-limb rehabilitation out- comes. The implemented system combined immersive virtual tasks—such as Touch Wall, Ball Launcher, Obstacle Dodge, and Stepping Stones—with real-time movement tracking, enabling detailed kinematic analysis and personalized therapy. A pilot study conducted at Sunnyview Rehabilitation Hospital involved seven patients with various mobility impairments, providing quantitative performance metrics and quali- tative user feedback. Results demonstrated consistent patient engagement, measurable im- provements in gait speed and task …

Association Of Non-Communicable Diseases With Severe Covid-19 Among People Living With And Without Diagnosed Hiv/Aids In New York State, Ravi Kumar Balu

Electronic Theses & Dissertations (2024 - present)

Background: People living with diagnosed HIV (PLWDH) have a higher chance of co-infections and co-morbidities than the general population. When SARS-CoV-2 was first reported in China in December 2019 and later declared a pandemic, it was speculated that PLWDH might be more prone to SARS-CoV-2 infection and severe disease outcomes given their increased vulnerability to other respiratory infections like influenza, pneumococcal pneumonia and tuberculosis. However, several facets of COVID-19 disease in PLWDH are incompletely understood, including whether non-communicable diseases (NCDs) are strong risk factors for severe disease outcomes and death as they are in the general population.

Methods: The data …