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Articles 257641 - 257670 of 5156456
Full-Text Articles in Entire DC Network
Haemodynamic Response Of Normal Aortic Valves To Stress Using Invasive, Non-Invasive, And Computational Techniques, Rob Eerdekens, Vijay Govindarajan, Nils P Johnson, Jesse P A Demandt, Mohamed El Farissi, Fabienne E Vervaat, Daniel T Johnson, Richard L Kirkeeide, Pim A L Tonino
Haemodynamic Response Of Normal Aortic Valves To Stress Using Invasive, Non-Invasive, And Computational Techniques, Rob Eerdekens, Vijay Govindarajan, Nils P Johnson, Jesse P A Demandt, Mohamed El Farissi, Fabienne E Vervaat, Daniel T Johnson, Richard L Kirkeeide, Pim A L Tonino
Faculty, Staff and Student Publications
AIMS: The haemodynamic physiology of the aortic valve has attracted renewed attention after the introduction of transcatheter aortic valve implantation (TAVI). Understanding normal valve function, especially under stress conditions, permits identification of early pathology and quantification of the extent to which TAVI restores normalcy. We aimed to describe the haemodynamic behaviour of a normal aortic valve during stress via invasive, non-invasive, and computational techniques.
METHODS AND RESULTS: Our cohort included subjects already undergoing invasive coronary angiography for clinical indications. Haemodynamic measurements were made invasively and non-invasively along with dobutamine infusion. Additionally, patient-specific anatomy from computed tomographic imaging served as input …
Rates Of Multidrug-Resistant Gram-Negative Bacterial Infections In Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study At A Lebanese Tertiary Medical Center, Ramia Zakhour, Sarah Khafaja, Rawan Korman, Celina F Boutros, Zeinab El Zein, Ahmad Chmaisse, Magda Haj, Amani Haddara, Zeina El-Houry, Malak Jbahi, Sarah Chamseddine, Samer Bou Karroum, Dana Al Oweini, Yolla Salama Youssef, Nour Youssef, Mayse Nasser, Danielle Fayad, Farida Abi Farraj, Clara El Nakib, Imad Isaac, Mireille Lteif, George F Araj, Ghassan S Dbaibo
Rates Of Multidrug-Resistant Gram-Negative Bacterial Infections In Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study At A Lebanese Tertiary Medical Center, Ramia Zakhour, Sarah Khafaja, Rawan Korman, Celina F Boutros, Zeinab El Zein, Ahmad Chmaisse, Magda Haj, Amani Haddara, Zeina El-Houry, Malak Jbahi, Sarah Chamseddine, Samer Bou Karroum, Dana Al Oweini, Yolla Salama Youssef, Nour Youssef, Mayse Nasser, Danielle Fayad, Farida Abi Farraj, Clara El Nakib, Imad Isaac, Mireille Lteif, George F Araj, Ghassan S Dbaibo
Faculty, Staff and Student Publications
Introduction: Multidrug resistant (MDR) Gram-negative bacterial infections are considered a major public health threat. The objectives of this study were to describe the epidemiology, potential contributing factors, and antimicrobial resistance patterns associated with infections caused by MDR Gram-negative bacteria (GNB) in non-immunocompromised children and adolescents.
Methods: This was a retrospective observational study conducted at the American University of Beirut Medical Center (AUBMC) from 2009 to 2017. The study included non-immunocompromised patients 18 years of age or younger with infections caused by GNB isolated from a sterile site or nonsterile site in the setting of clinical infection.
Results: A total of …
Targeting Ferroptosis For Neuroprotection: Potential Therapeutic Avenues In Neurodegenerative And Neuropsychiatric Diseases, Muhammad S Khan, Qichan Hu, Kendrix Okeibunor, Liang Ma, Jean C Bopassa
Targeting Ferroptosis For Neuroprotection: Potential Therapeutic Avenues In Neurodegenerative And Neuropsychiatric Diseases, Muhammad S Khan, Qichan Hu, Kendrix Okeibunor, Liang Ma, Jean C Bopassa
Faculty, Staff and Student Publications
Ferroptosis is an iron-dependent programmed cell death that plays an important role in neurodegenerative and neuropsychiatric diseases. In the present study, we have highlighted how different risk factors are involved in the induction of ferroptosis in brain cells. In addition, we also demonstrated how ferroptosis plays an important role in different brain diseases. In our study why we focused and elaborated on the mechanisms of ferroptosis only in brain cells (Neurons, oligodendrocytes, and microglia) because they are particularly vulnerable to such kind of cell death. Additionally, brain cells are more dependent on mitochondrial function, iron regulation, and high levels of …
Mic60/Mitofilin Inhibitor, Miclxin, Induces Rat H9c2 Cardiomyoblast Death By Inhibiting The Removal Of Damaged Mitochondria, Muhammad S Khan, Somayyeh Nasiripour, Michele Oyarzabal, Swati Banerjee, Kumar Sharma, Manzoor A Bhat, Jean C Bopassa
Mic60/Mitofilin Inhibitor, Miclxin, Induces Rat H9c2 Cardiomyoblast Death By Inhibiting The Removal Of Damaged Mitochondria, Muhammad S Khan, Somayyeh Nasiripour, Michele Oyarzabal, Swati Banerjee, Kumar Sharma, Manzoor A Bhat, Jean C Bopassa
Faculty, Staff and Student Publications
Mitochondrial dysfunction is a hallmark of various pathologic conditions, including ischemia/reperfusion injury, stroke, myocardial infarction, neurodegeneration and metabolic syndrome. As with all biological organelles, the function of mitochondria is tightly linked to their structure. The inner mitochondrial membrane is a highly regulated membrane with a large surface area that hosts the electron transport chain machinery, generates the membrane potential necessary for ATP generation, and forms the signature cristae folds of mitochondria. The mitochondrial inner membrane protein (Mitofilin/Mic60) is part of a large complex that constitutes the mitochondrial inner membrane organizing system, which is critical in maintaining mitochondrial architecture and function. …
Decline In Attrition Rates In United States Pediatric Residency And Fellowship Programs, 2007–2020: A Repeated Cross-Sectional Study, Emma Omoruyi, Greg Russell, Kimberly Montez
Decline In Attrition Rates In United States Pediatric Residency And Fellowship Programs, 2007–2020: A Repeated Cross-Sectional Study, Emma Omoruyi, Greg Russell, Kimberly Montez
Faculty, Staff and Student Publications
Purpose: Declining fill rates in US pediatric residency and subspecialty programs requires trainee retention. Attrition, defined as transfers, withdrawals, dismissals, unsuccessful completions, or deaths, disrupts program function and impacts the pediatric workforce pipeline. It aims to evaluate attrition trends among pediatric residents and fellows in Accreditation Council for Graduate Medical Education (ACGME)-accredited programs from 2007 to 2020.
Methods: This repeated cross-sectional study analyzed publicly available ACGME Data Resource Book records. Attrition rates and 95% confidence intervals (CIs) were calculated overall and by subspecialty. Logistic regression assessed temporal changes; odds ratios (ORs) compared 2020 to 2007.
Results: From 2007-2020, pediatric residents …
National Landscape Of Underrepresented In Medicine Visiting Medical Student Programs In Pediatrics, Tyler K Smith, Rebecca Blankenburg, Ann E Burke, Emma A Omoruyi, Wendla Sensing, Tiffany Ruan, David D Williams, Onyi Oligbo, Lahia Yemane
National Landscape Of Underrepresented In Medicine Visiting Medical Student Programs In Pediatrics, Tyler K Smith, Rebecca Blankenburg, Ann E Burke, Emma A Omoruyi, Wendla Sensing, Tiffany Ruan, David D Williams, Onyi Oligbo, Lahia Yemane
Faculty, Staff and Student Publications
Objective: Underrepresented in medicine visiting medical student programs (UIM-VMSPs) have gained popularity across specialties as an intervention to diversify residency programs; however, no study has explored the national landscape of these programs in pediatrics. This study aimed to characterize program components, residency rank and match outcomes, benefits, challenges, and lessons learned about UIM-VMSPs in pediatrics nationally.
Methods: From September to December 2023, the authors conducted a national, cross-sectional, mixed methods study surveying program leaders of UIM-VMSPs identified on the Association of Pediatric Program Directors website. The authors used descriptive statistics to analyze the data and conventional content analysis for free-text …
Implantable Loop Recorder Identifies Sustained Ventricular Tachycardia In A Pediatric Patient Despite Negative Ep Study: A Case Report, Jia Yue Liu, Mohammed T Numan
Implantable Loop Recorder Identifies Sustained Ventricular Tachycardia In A Pediatric Patient Despite Negative Ep Study: A Case Report, Jia Yue Liu, Mohammed T Numan
Faculty, Staff and Student Publications
Experience of loop recorders in pediatric patients is limited. We report using a loop recorder to detect ventricular arrhythmias in a 16-year-old female who had years of palpitations despite inconclusive noninvasive and invasive electrophysiological testing.
Case Report: Coronary Vasospasm Precipitating Stemi And Polymorphic Ventricular Tachycardia-A Case Of Cardiotoxicity From 5-Fu Based Chemotherapy In A 41-Year-Old Woman, Ammar Hasnie, Zachary Neace, Kristin Ellison, Aaron Hesselson, Karam Ayoub, Mohammed Al-Yafi, Amit Arbune
Case Report: Coronary Vasospasm Precipitating Stemi And Polymorphic Ventricular Tachycardia-A Case Of Cardiotoxicity From 5-Fu Based Chemotherapy In A 41-Year-Old Woman, Ammar Hasnie, Zachary Neace, Kristin Ellison, Aaron Hesselson, Karam Ayoub, Mohammed Al-Yafi, Amit Arbune
Faculty, Staff and Student Publications
Background: Intravenous 5-fluorouracil (5-FU), in combination with oxaliplatin and folinic acid, makes up a chemotherapy regimen commonly referred to as FOLFOX. It is well-established for its efficacy in patients with advanced colorectal cancer; however, the benefits are accompanied by potential side effects that warrant careful consideration. Common toxicities can range from nausea and vomiting to neuropathy. Cardiotoxicities related to FOLFOX and fluoropyrimidines in general are extremely rare but can easily be fatal.
Case presentation: A 41-year-old woman who was recently diagnosed with stage IIIc colorectal cancer after she underwent a subtotal colectomy was admitted to the Oncology clinic for further …
Rho/Rock Pathway As A Therapeutic Target In Multiple Diseases, Zixiu Cheng, Shannon Erhardt, Jun Wang
Rho/Rock Pathway As A Therapeutic Target In Multiple Diseases, Zixiu Cheng, Shannon Erhardt, Jun Wang
Faculty, Staff and Student Publications
The Rho/ROCK (Rho-associated coiled-coil-containing protein kinase) signaling pathway plays a pivotal role in regulating diverse cellular processes, including cytoskeletal organization, cell migration, proliferation, and apoptosis. Dysregulation of this pathway has been implicated in the pathogenesis of various diseases, such as cardiovascular disorders, cancer, neurological conditions, and fibrotic diseases. Accumulating evidence supports the therapeutic potential of targeting Rho/ROCK, with several inhibitors currently under investigation or in clinical use. This review summarizes the molecular mechanisms underlying Rho/ROCK signaling, explores its involvement in disease progression, and discusses recent advances in the development of and the clinical application of ROCK inhibitors as promising therapeutic …
Revisiting Cytomegalovirus In Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: Current Strategies For Prevention And Management In The Letermovir Era, Lisa Hiskey, Diego R Hijano, Ramia Zakhour
Revisiting Cytomegalovirus In Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: Current Strategies For Prevention And Management In The Letermovir Era, Lisa Hiskey, Diego R Hijano, Ramia Zakhour
Faculty, Staff and Student Publications
CMV infection remains the most common clinically significant infection in pediatric allogeneic hematopoietic stem cell (HCT) recipients, with seropositive recipients of transplants from seronegative donors at the highest risk for complications. In recent years, letermovir, a novel antiviral with a favorable toxicity profile, was approved first for adults and more recently for pediatric patients for the primary prophylaxis of CMV infection and disease in high-risk HCT recipients. Growing evidence from real-life data regarding the safety and efficacy of letermovir has transformed the landscape of CMV disease in HCT transplant recipients and led to a paradigm shift from a preemptive approach …
Editorial: Surface Emg And Other Measurement Techniques In Rehabilitation Research And Practice: Are New Educational Programs Needed?, Marco Tramontano, Sheng Li, Roberto Merletti
Editorial: Surface Emg And Other Measurement Techniques In Rehabilitation Research And Practice: Are New Educational Programs Needed?, Marco Tramontano, Sheng Li, Roberto Merletti
Faculty, Staff and Student Publications
No abstract provided.
Mental Health Outcomes Of Latino Emerging Adults With Autism Spectrum Disorder In A Community-Based, Transition To Adulthood Program, Antonio F Pagán, Ana C Ramirez, Katherine A Loveland, Cecilia Montiel-Nava, Ron Acierno
Mental Health Outcomes Of Latino Emerging Adults With Autism Spectrum Disorder In A Community-Based, Transition To Adulthood Program, Antonio F Pagán, Ana C Ramirez, Katherine A Loveland, Cecilia Montiel-Nava, Ron Acierno
Faculty, Staff and Student Publications
Latino individuals with autism spectrum disorder (ASD) face unique challenges during their transition to adulthood. This study evaluates ¡Iniciando! la Adultez, a culturally adapted behavioral health program aimed at addressing the co-occurring mental health needs of Latino young adults with ASD and their families. The program integrates culturally relevant elements to enhance engagement and effectiveness. Results indicated that the behavioral health intervention was associated with significant reductions in anxiety and depressive symptoms, highlighting the urgent need for tailored behavioral health services in this population. Additionally, the involvement of parents in group therapy demonstrated a positive impact on both parental and …
Peer Support During In Vivo Exposure Homework Increases Likelihood Of Prolonged Exposure Therapy Completion, Melba A Hernandez-Tejada, Madeline J Bruce, Wendy Muzzy, Anna Birks, Giovanni Macedo E Cordeiro, Stephanie M Hart, Stephanie Hamski, Ron Acierno
Peer Support During In Vivo Exposure Homework Increases Likelihood Of Prolonged Exposure Therapy Completion, Melba A Hernandez-Tejada, Madeline J Bruce, Wendy Muzzy, Anna Birks, Giovanni Macedo E Cordeiro, Stephanie M Hart, Stephanie Hamski, Ron Acierno
Faculty, Staff and Student Publications
Exposure-based treatments such as prolonged exposure therapy (PE) are effective for veterans with PTSD. However, dropout rates as high as 50% are common. The Department of Veterans Affairs employs peers to increase mental health treatment engagement, however peers are not routinely used to help patients complete PE homework assignments. The present study included 109 veterans who decided to drop out from exposure-based treatment after completing seven or fewer sessions and used a randomized controlled design to compare PE treatment completion rates in response to 2 forms of peer support: (1) standard weekly telephone-based peer support vs. (2) peer-assisted in vivo …
Therapeutic Alliance In A Culturally Tailored Transition Program For Latino Young Adults With Autism And Their Families, Antonio F Pagán, Katherine A Loveland, Ron Acierno
Therapeutic Alliance In A Culturally Tailored Transition Program For Latino Young Adults With Autism And Their Families, Antonio F Pagán, Katherine A Loveland, Ron Acierno
Faculty, Staff and Student Publications
Latino young adults with autism spectrum disorder (ASD) often face barriers to accessing culturally appropriate interventions that support adaptive functioning and family dynamics. Therapeutic alliance, the collaborative and trusting relationship between participants and providers, is a critical component of intervention success, yet its role in culturally tailored programs for Latino families remains underexplored. The present study examined therapeutic alliance in ¡Iniciando! la Adultez, a 12-week, culturally adapted intervention for Latino young adults with ASD and their Spanish-speaking parents. The program integrates Latino cultural values and language and consists of parent group therapy, young adult group therapy, and individual therapy sessions. …
Examining The Relationship Between Cardiometabolic Risk Factors And Telomere Length In Women: A Systematic Review, Jeni Page, Catherine Stephens, Melissa A Richard, Elizabeth Lyons, Elizabeth Baumler, M Terese Verklan, Elizabeth Lorenzo
Examining The Relationship Between Cardiometabolic Risk Factors And Telomere Length In Women: A Systematic Review, Jeni Page, Catherine Stephens, Melissa A Richard, Elizabeth Lyons, Elizabeth Baumler, M Terese Verklan, Elizabeth Lorenzo
Faculty, Staff and Student Publications
Background and objectives: Cardiometabolic syndrome (CMS) poses a significant public health challenge due to its rising prevalence in aging and significant healthcare costs. Recent studies have suggested telomere length (TL), a marker of cellular aging, may be impacted by CMS among women, but comprehensive evidence remains limited. This study aimed to examine the association between CMS risk factors (increased waist circumference [WC], elevated blood pressure, impaired fasting blood glucose, elevated triglycerides, decreased high-density lipoproteins) and TL in women, with consideration of age and race or ethnicity.
Research design and methods: A systematic review was conducted following PRISMA guidelines, with searches …
Consistent Frontal-Limbic-Occipital Connections In Distinguishing Treatment-Resistant And Non-Treatment-Resistant Schizophrenia, Yijie Zhang, Shuzhan Gao, Chuang Liang, Juan Bustillo, Peter Kochunov, Jessica A Turner, Vince D Calhoun, Lei Wu, Zening Fu, Rongtao Jiang, Daoqiang Zhang, Jing Jiang, Fan Wu, Ting Peng, Xijia Xu, Shile Qi
Consistent Frontal-Limbic-Occipital Connections In Distinguishing Treatment-Resistant And Non-Treatment-Resistant Schizophrenia, Yijie Zhang, Shuzhan Gao, Chuang Liang, Juan Bustillo, Peter Kochunov, Jessica A Turner, Vince D Calhoun, Lei Wu, Zening Fu, Rongtao Jiang, Daoqiang Zhang, Jing Jiang, Fan Wu, Ting Peng, Xijia Xu, Shile Qi
Faculty, Staff and Student Publications
Background and hypothesis: Treatment-resistant schizophrenia (TR-SZ) and non-treatment-resistant schizophrenia (NTR-SZ) lack specific biomarkers to distinguish from each other. This investigation aims to identify consistent dysfunctional brain connections with different atlases, multiple feature selection strategies, and several classifiers in distinguishing TR-SZ and NTR-SZ.
Study design: 55 TR-SZs, 239 NTR-SZs, and 87 healthy controls (HCs) were recruited from the Affiliated Brain Hospital of Nanjing Medical University. Resting-state functional connection (FC) matrices were constructed from automated anatomical labeling (AAL), Yeo-Networks (YEO) and Brainnetome (BNA) atlases. Two feature selection methods (Select From Model and Recursive Feature Elimination) and four classifiers (Adaptive Boost, Bernoulli Naïve …
A Prior-Knowledge-Guided Feature Selection Method And Its Application To Biomarker Identification Of Schizophrenia, Ying Xing, Godfrey D Pearlson, Peter Kochunov, Vince D Calhoun, Yuhui Du
A Prior-Knowledge-Guided Feature Selection Method And Its Application To Biomarker Identification Of Schizophrenia, Ying Xing, Godfrey D Pearlson, Peter Kochunov, Vince D Calhoun, Yuhui Du
Faculty, Staff and Student Publications
Despite considerable efforts to uncover the neural basis of psychiatric disorders using neuroimaging, few methods utilize intrinsic brain-derived knowledge, leading to limited specificity and discriminability in biomarker identification. To leverage the inherent characteristics within the brain, we propose a prior-knowledge-guided feature selection method to flexibly unveil discriminative and target-oriented biomarkers of psychiatric disorders. Specifically, we construct a constrained sparse regularization allowing for the flexible integration of diverse prior knowledge to identify sparse neuroimaging features linked to specific psychopathology. Additionally, we simultaneously integrate graph-based regularization and redundancy-removal regularization to further ensure the discriminability and independence among the selected features. Different priors …
Detection Of Erg11 Gene Mutation In Coding And Non-Coding Regions Of Clinical Candida Glabrata (Nakaseomyces Glabratus) Isolates From Pakistan, Saba Memon, Najia Karim Ghanchi, Urooj Zafar, Joveria Farooqi, Sadaf Zaka, Kauser Jabeen
Detection Of Erg11 Gene Mutation In Coding And Non-Coding Regions Of Clinical Candida Glabrata (Nakaseomyces Glabratus) Isolates From Pakistan, Saba Memon, Najia Karim Ghanchi, Urooj Zafar, Joveria Farooqi, Sadaf Zaka, Kauser Jabeen
Faculty, Staff and Student Publications
Azoles inhibit the cytochrome P450-dependent enzyme lanosterol 14α-demethylase (CYP51) that is encoded by the ERG11 gene. Azole resistance in Candida species arises through different mechanisms, like mutations in the ERG11 gene, ERG11 overexpression, CDR1,2 (Candida drug resistance) overexpression that actively efflux azole drugs, reducing their intracellular concentration and therapeutic effectiveness, and biofilm formation. We sequenced the ERG11 gene to determine mutations in the coding and non-coding regions of ERG11 in clinical isolates of Candida glabrata (Nakaseomyces glabratus) from Pakistan. Eight C. glabrata (N. glabratus) strains from our fungal strain bank (five fluconazole-resistant and …
The Urgent Need For Well-Being Programs In Medical Residencies In Brazil, Marcelo Bruno Generoso, Pedro Shiozawa, Ricardo Uchida, Marsal Sanches
The Urgent Need For Well-Being Programs In Medical Residencies In Brazil, Marcelo Bruno Generoso, Pedro Shiozawa, Ricardo Uchida, Marsal Sanches
Faculty, Staff and Student Publications
No abstract provided.
Brazilian Psychiatric Association Guidelines For The Treatment Of Social Anxiety Disorder, Leonardo Baldaçara, Thales Marcon Almeida, Diogo Cesar Dos Santos, Ana Beatriz Paschoal, Aldo Felipe Pinto, Luiz Antonio Vesco Gaiotto, Diogo De Lacerda Veiga, Fabiano Franca Loureiro, Leandro Fernandes Malloy-Diniz, Roseli Lage De Oliveira, Quirino Cordeiro, Marsal Sanches, Antônio E Nardi, Antônio Geraldo Da Silva, Ricardo R Uchida
Brazilian Psychiatric Association Guidelines For The Treatment Of Social Anxiety Disorder, Leonardo Baldaçara, Thales Marcon Almeida, Diogo Cesar Dos Santos, Ana Beatriz Paschoal, Aldo Felipe Pinto, Luiz Antonio Vesco Gaiotto, Diogo De Lacerda Veiga, Fabiano Franca Loureiro, Leandro Fernandes Malloy-Diniz, Roseli Lage De Oliveira, Quirino Cordeiro, Marsal Sanches, Antônio E Nardi, Antônio Geraldo Da Silva, Ricardo R Uchida
Faculty, Staff and Student Publications
Social anxiety disorder (SAD), one of the most prevalent anxiety disorders, is not well recognized. In most cases, SAD follows an unremitted and chronic course, affecting individual functioning in relationships, education, and work. Due to the disorder’s relevance in Brazil, guideline-based treatments adapted to the Brazilian social and economic context are needed. We conducted a systematic review assessing several treatment modalities for SAD. PubMed, Cochrane, SciELO, and ClinicalTrials.gov were searched using the Medical Subject Headings social anxiety disorder and social phobia. Of the 438 selected articles, 20 were selected. Selective serotonin reuptake inhibitors are considered a first-line treatment for SAD …
Warrior Life Transition Program, Joshua Gartner
Warrior Life Transition Program, Joshua Gartner
OT Doctoral Capstones
The problem that exists is that the Willliam Beaumont Army Medical Center (WBAMC), Internal Medicine Clinic (IMC) treats issues amongst active duty and veteran personnel in a reactionary manner. 6 domains of need: Mental health, (including, sub-domains of anxiety, depression, PTSD, and stress), occupations, pain, family life/connection (Relationships), sleep and alcohol/ substance abuse. Currently there is no one assessment at the WBAMC IMC that looks to assess all of these areas in a reactive way. This project was to develop a reactive assessment to address these domains of need.
Supporting The Parents Of Transition Aged Students With Autism, Miguel Duran
Supporting The Parents Of Transition Aged Students With Autism, Miguel Duran
OT Doctoral Capstones
The present capstone project sought to develop and implement an 8-week parent support program for the parents of transition aged youths diagnosed with autism spectrum disorder residing within the Socorro Independent School District. The parent support group included the topics of preparing for the transition process, state and local resources, and identifying caregiver strain for the first half of the program. The latter half of the program consisted of self-care and leisure activities for the parents to address levels of caregiver strain. The goal of the program was to identify potential changes in three areas: caregiver strain, perceived levels of …
Bright Futures: A Transitional Resource Guide, Leslie Ayala
Bright Futures: A Transitional Resource Guide, Leslie Ayala
OT Doctoral Capstones
Bright Futures: A Transitional Resource Guide (BF) is a caregiver-informed collection of personal narratives shared by 15 caregivers of children with Down syndrome (DS), designed to promote preparedness, advocacy, and connection through storytelling and peer-recommended resources during key life transitions, including starting school and entering adulthood. Professionally published on the DS Coalition for El Paso website, BF was developed in collaboration with a software developer and funded by a grant from the College of Health Sciences at the University of Texas at El Paso, ensuring long-term, public accessibility.
Goals of BF:
- Disseminate trusted resources and lived experiences among caregivers of …
The Role Of Occupational Therapy In Postnatal Mental Health: An Eight-Week Postpartum Program, Paola Quiroz
The Role Of Occupational Therapy In Postnatal Mental Health: An Eight-Week Postpartum Program, Paola Quiroz
OT Doctoral Capstones
Postpartum mental health includes various conditions such as postpartum anxiety and postpartum depression amongst others (Barbic Skye et al., 2021). Rates of postpartum depression (PPD) have been increasing in recent years, impacting mothers, children and entire families by changing the way a mother interacts with others (WHO, 2024). Postpartum mothers face unique challenges when transitioning into motherhood resulting in increased maternal stress and ultimately leading to PPD or PPA. Although rates of PPD and PPA are increasing, there is limited research involving non-pharmaceutical treatment options for new mothers.
Occupational therapy (OT) plays a vital role in maternal mental health because …
Reclaiming Control: A Self-Management Education Program For Cancer Survivors, Monica Elisa Gutierrez
Reclaiming Control: A Self-Management Education Program For Cancer Survivors, Monica Elisa Gutierrez
OT Doctoral Capstones
Cancer survivors face physical, emotional, and cognitive side effects after cancer treatment which negatively affects their quality of life (QOL).
A remote 6-week self-management program was implemented to educate survivors on how to manage these challenges. Comparison of pre- and post-program surveys demonstrated increased confidence in managing side effects after participation in the program, indicating that self-management interventions can effectively enhance survivors’ symptom management skills. The Self-Management Program is effective in empowering cancer survivors, improving self-efficacy, and enhancing QOL.
Problematic Technology Use: An Education Program, Elijah Duran
Problematic Technology Use: An Education Program, Elijah Duran
OT Doctoral Capstones
There is a growing body of research on problematic technology use and its impact on children with autism. Studies have shown that excessive or unbalanced use of technology may contribute to challenges in mental health and social functioning for this population (Ang et al., 2018; Cerniglia et al., 2017; Ezeh et al., 2021; Hoge et al., 2017; Kawabe et al., 2016; Small et al., 2020; Yucelyigit & Aral, 2018). However, there is limited research on how this issue is being practically addressed. Children with autism, who are already at higher risk for developing problematic behaviors with technology (Normand et al., …
Pasos Seguros: Investigating The Impact Of Latin Dance And Fall Prevention Education On Fall Risk In Older Adults, Noelia De La Rosa
Pasos Seguros: Investigating The Impact Of Latin Dance And Fall Prevention Education On Fall Risk In Older Adults, Noelia De La Rosa
OT Doctoral Capstones
Introduction: Falls are a leading cause of injury and mortality among older adults, posing a significant public health concern worldwide. By participating in fun, culturally relevant, and recreational fall prevention interventions, older adults are more likely to be motivated and stay engaged in fall prevention educational programs.
Methods: Pasos Seguros (confident steps) provided six weekly 60-minute sessions at the UTEP Rehab Sciences Complex, each including 45 minutes of chair-supported Latin dance instruction (cumbia, bachata, salsa) followed by 15 minutes of fall prevention education (home safety, medication effects, and emergency preparedness) through the UTEP Osher Lifelong Learning Institute.
Results: A paired-samples …
Strength-Based Peer Mentoring To Empower Independence For Adults With Autism, Annmarie De La Rosa
Strength-Based Peer Mentoring To Empower Independence For Adults With Autism, Annmarie De La Rosa
OT Doctoral Capstones
Adults with autism face disproportionately high rates of unemployment or underemployment, limited engagement in post-secondary education, and restricted opportunities for social participation. This is largely due to the abrupt discontinuation of services after high school—often referred to as the “service cliff” (Roux, 2015). The loss of structured supports can result in a decline in functional independence, increased mental health concerns such as anxiety and depression, and heightened social isolation (Chun et al., 2023; Schiltz et al., 2021).
This Capstone project aimed to address the unmet post-secondary needs of young adults with autism by implementing a peer mentoring program grounded in …
Risk Factors For Progression Of Intracranial Hemorrhage After Initiation Of Vte Chemoprophylaxis: An Evaluation Of 1390 Tbi Patients, Keith Walter Burczak, Jan-Michael Van Gent, Devi Bavishi, Joel James, Thomas W Clements, Thaddeus J Puzio, Bryan A Cotton
Risk Factors For Progression Of Intracranial Hemorrhage After Initiation Of Vte Chemoprophylaxis: An Evaluation Of 1390 Tbi Patients, Keith Walter Burczak, Jan-Michael Van Gent, Devi Bavishi, Joel James, Thomas W Clements, Thaddeus J Puzio, Bryan A Cotton
Faculty, Staff and Student Publications
Objectives: Patients with traumatic intracranial hemorrhage (ICH) often undergo early stability CT scans to evaluate for progression of bleeding. The factors associated with progression after initiating venous thromboembolism (VTE) chemoprophylaxis (CP) remain poorly described. This study aimed to determine the rate of and factors associated with ICH progression following CP initiation.
Methods: This retrospective observational study included adult (≥16 years) polytrauma patients with blunt or penetrating traumatic brain injury (TBI) admitted between September 2016 and December 2021. Progression was defined as a radiographic increase in ICH following VTE CP initiation, determined by neurosurgery or radiology faculty. Postprophylaxis CT scans were …
Variation Exists In Venous Thromboembolism Prophylaxis In Traumatic Brain Injury Despite National Guidelines: Insights From A Recent Aast Survey Study, Keith Walter Burczak, Jan-Michael Van Gent, Devi Bavishi, Gabrielle E Hatton, Patrick B Murphy, Asanthi Ratnasekera, Thomas W Clements, Rachel S Morris, Christopher Tignanelli, Bryan A Cotton, Thaddeus J Puzio
Variation Exists In Venous Thromboembolism Prophylaxis In Traumatic Brain Injury Despite National Guidelines: Insights From A Recent Aast Survey Study, Keith Walter Burczak, Jan-Michael Van Gent, Devi Bavishi, Gabrielle E Hatton, Patrick B Murphy, Asanthi Ratnasekera, Thomas W Clements, Rachel S Morris, Christopher Tignanelli, Bryan A Cotton, Thaddeus J Puzio
Faculty, Staff and Student Publications
Background: Best practice guidelines from trauma-focused organizations support early (< 72 hours) venous thromboembolism (VTE) chemoprophylaxis initiation in traumatic brain injury (TBI) patients. Recent literature suggests that an even more aggressive initiation (24 hours) is safe and efficacious. It is unknown how current practice aligns with the existing literature and best practice guidelines. We performed a national survey to characterize variation in trauma surgeons' reported practices and attitudes regarding VTE chemoprophylaxis initiation in TBI patients with the hypothesis that they will vary widely.
Methods: All 1700 American Association for the Surgery of Trauma members were surveyed online. Members who routinely cared for patients with TBI were asked to proceed with the survey. Descriptive data were reported. The questions characterized institutional guidelines, and if none existed, individual practice patterns regarding goal timeline of VTE chemoprophylaxis in TBI patients.
Results: 374 members (22%) completed the survey. Most respondents worked at academic institutions (40%) and represented a level one trauma center (44%). Enoxaparin was the most common VTE chemoprophylactic (73%) with most using weight-based dosing (76%) …