Digital Commons Network^™

Gans And Synthetic Financial Data: Calculating Var*, David E. Allen, Leonard Mushunje, Shelton Peiris

Research outputs 2022 to 2026

Generative Adversarial Neural nets (GANs) are a new branch of machine learning techniques. A GAN learns to generate new data from the training data set. We examine the characteristics of the fake financial data using GANs trained on samples of daily S&P 500 and FTSE 100 index values. GANs feature two competing neural networks in a game theoretic context. The Generator net generates pseudo data that is presented to the discriminator net which then attempts to distinguish between the real and the fake data. This facilitates unsupervised learning on the dataset. The generative network generates data sets, while the discriminative …

Physiological Plateaus During Normal Labor And Birth: A Novel Definition, Marina Weckend, Kylie Mccullough, Christine Duffield, Sara Bayes, Clare Davison

Research outputs 2022 to 2026

Background: Diagnoses of labor dystocia, and subsequent labor augmentation, make one of the biggest contributions to childbirth medicalization, which remains a key challenge in contemporary maternity care. However, labor dystocia is poorly defined, and the antithetical concept of physiological plateaus remains insufficiently explored. Aim: To generate a definition of physiological plateaus as a basis for further research. Methods: This qualitative study applied grounded theory methods and comprised interviews with 20 midwives across Australia, conducted between September 2020 and February 2022. Data were coded in a three-phase approach, starting with inductive line-by-line coding, which generated themes and subthemes, and finally, through …

Sleep Discrepancy And Cognitive Function In Community-Dwelling Older Adults, Nadia Soh, Stephanie R. Rainey-Smith, James D. Doecke, Rodrigo Canovas, Romola S. Bucks, Melissa Ree, Michael Weinborn

Research outputs 2022 to 2026

This was the first study to use cluster analysis to characterise sleep discrepancy (the discordance between self-reported and objective sleep) across multiple sleep parameters, in community-dwelling older adults. For sleep efficiency, negative discrepancy (the tendency to self-report worse sleep than objectively-measured) was associated with poorer memory, independent of insomnia severity, depressive symptoms and objective sleep. This suggests a unique role for sleep discrepancy as a possible risk factor for future cognitive decline, and warrants the need for further research.

Accessible Tourism: Tourists With Physical Disability - Segmentation Based On Perceived Travel Barriers, Changjiang Tao, Songshan Huang, Jin Wang, Guanghui Qiao

Research outputs 2022 to 2026

Purpose: This study aims to explore the heterogeneity of the tourist market for people with a physical disability (PwPD) based on travel barriers, to serve them better, from a tourism marketing perspective. Design/methodology/approach: A market segmentation analysis was conducted on a sample of 480 PwPD in Sichuan Province, China, based on their perceived travel barriers. Data were obtained through three on-site and four online surveys. A four-step factor-item mixed segmentation, including factor analysis, cluster analysis, discriminant analysis and chi-square tests, was applied to examine the differences among PwPD tourist market segments in terms of various demographic characteristics, disability conditions (e.g. …

Academic Literacy In Enabling Education Programs In Australian Universities: A Shared Pedagogy, Charmaine Davis, Kathryn Lawson, Lisa Duffy

Research outputs 2022 to 2026

Widening participation in higher education has led to the global expansion of universities, increased student and program diversity, and greater provision of flexible pathways into university. Critical to supporting a growing student body is helping all students develop their ability to communicate confidently and effectively in their academic communities. This research employs a collaborative benchmarking framework to explore academic literacy instruction in pathway or ‘enabling’ programs across nine Australian universities. While prevailing assumptions hold that such programs are overly diverse, the findings demonstrate that these programs have developed remarkably similar approaches; in particular, the investigation found that the programs all …

Investigating The Acceptability Of Modified Constraint-Induced Movement Therapy Among Stroke Survivors And Carers: A Qualitative Study, Ashan Weerakkody, Erin Godecke, Barby Singer

Research outputs 2022 to 2026

Purpose: To investigate the acceptability of modified constraint-induced movement therapy (mCIMT) among stroke survivors and carers within an early-supported discharge (ESD) service, and to inform further adaptations of the program to enhance acceptability. Methods: Qualitative study within a mixed methods process evaluation of mCIMT implementation. Semi-structured interviews were analysed using reflexive thematic analysis and mapped to the Capability, Opportunity, Motivation- Behaviour (COM-B) model. Results: Fifteen stroke survivors and ten carers participated. Five themes were generated and mapped to the COM-B. Participants attributed functional improvements to the program whilst also encountering several challenges with returning home after stroke (Capability- physical); the …

Epidemiological Principles In Claims Of Causality: An Enquiry Into Repetitive Head Impacts (Rhi) And Chronic Traumatic Encephalopathy (Cte), Lauren V. Fortington, J. David Cassidy, Rudolph J. Castellani, Andrew J. Gardner, Andrew S. Mcintosh, Michael Austen, Zachary Yukio Kerr, Kenneth L. Quarrie

Research outputs 2022 to 2026

Determining whether repetitive head impacts (RHI) cause the development of chronic traumatic encephalopathy (CTE)-neuropathological change (NC) and whether pathological changes cause clinical syndromes are topics of considerable interest to the global sports medicine community. In 2022, an article was published that used the Bradford Hill criteria to evaluate the claim that RHI cause CTE. The publication garnered international media attention and has since been promoted as definitive proof that causality has been established. Our counterpoint presents an appraisal of the published article in terms of the claims made and the scientific literature used in developing those claims. We conclude that …

Exercise In Cancer Care For People With Lung Cancer: A Narrative Synthesis, Kellie Toohey, David Mizrahi, Nicolas H. Hart, Ben Singh, Pedro Lopez, Maddison Hunter, Robert U. Newton, Kathryn H. Schmitz, Diana Adams, Lara Edbrooke, Sandi Hayes

Research outputs 2022 to 2026

Objectives: Lung cancer is the second most common cancer diagnosed worldwide, resulting in significant physical and psychological consequences. In this narrative review, we explore the role of exercise as an adjunct therapy to counteract health issues experienced by people before, during and after treatment for lung cancer, and offer recommendations for exercise prescription and future research. Design: Narrative cornerstone review. Methods: A narrative review was conducted to explore the role of exercise in cancer care for people diagnosed with lung cancer. Results: Improvements in fitness, strength and quality of life have been demonstrated in people with lung cancer following participation …

Outdoor Adventure Education For Adolescent Social And Emotional Wellbeing: A Systematic Review And Meta-Analysis, Michael J.A. Down, D. Picknoll, T. Edwards, F. Farringdon, G. Hoyne, B. Piggott, M. C. Murphy

Research outputs 2022 to 2026

This study examines the effects of OAE on adolescent social and emotional wellbeing and their contributors. Intervention studies (single or multi-arm) assessing the effects of OAE on wellbeing were included. Meta-analysis was conducted on outcomes of interest, and the Cochrane Risk of Bias (RoB) Tool assessed RoB in multi-arm studies. Four studies assessed within-group change (n = 368), and six assessed between-group change (n = 1,143). Findings indicate significant between-group improvements in resilience, self-esteem and social belonging when OAE was compared to no intervention, but no self-efficacy and overall wellbeing changes were observed. Studies were at high risk of bias, …

Responding To Children’S Voices: The New Frontier In Education Policy Reform, Amelia Ruscoe

Research outputs 2022 to 2026

More than thirty years on from the United Nations Convention of the Child honouring a child’s right to be heard (Article 12) has unlocked a new frontier in ethical research. In education, children have demonstrated competence to contribute with insight to recent policy development in Australia. This paper provides further evidence of the critical role children stand to play in education reform. A post-structural perspective is adopted and underpinned with Foucauldian theory of discursive power in the context of school-based affordances. Visual and dialogic qualitative methods are used to compare the impact of powerful discourses upon children’s affordances in the …

The Nutbush Dance Reframed: Further Analysis Related To ‘Doing The Nutbush’, Jon Stratton, Panizza Allmark

Research outputs 2022 to 2026

This article supplements our earlier article on the Nutbush dance, ‘Doing the Nutbush’. After that was published, there was a media frenzy which resulted in many comments on The Guardian site and on the ABC Facebook site. We also received a number of emails. All these contributions have helped fine-tune the history of the dance that we have been examining. Two key things became clear. Around 1970 there was a push in state education departments across Australia to substitute the American line dance, the Madison, for bush dances as a way of updating and making more relevant dance for primary …

Work-Life Imbalance, Burning Out, Feeling Down, I Will Quit, But Quietly – The Case Of Hospitality Employees, Catherine Prentice, Sergio Dominique-Ferreira, Xuequn Wang, Jesse Tuominen, Márcia Duarte, Helena Rocha

Research outputs 2022 to 2026

Given the long and irregular working hours and low wages in the hospitality sector, employees often experience poor well-being and suffer from burnout. Instead of leaving their jobs, these employees engage in quiet quitting, which negatively impacts organizations. This study investigates the relationships between role conflicts, employee well-being, burnout, and quiet quitting among hospitality employees. The study was undertaken at hotels with different star ratings in Portugal. Data were collected from both frontline and backstage employees from different departments at the survey hotels, Structural equation modeling with Mplus was performed to analyze the data. The results indicate that role conflicts …

Creation And Use Of Sbs’S The Boat; Principles For The Co-Creation Of Online Interactive Learning Environments For Innovative Digital Pedagogy, Prue Miles, Kylie Boltin

Research outputs 2022 to 2026

Teachers and students rely more on online-learning environments than ever before, including open, trusted and high-quality online learning resources produced by public broadcasters. For educators, this represents both an inspiration and challenge in the wake of new techologies and online learning environments. This article is a case study of one such online learning environment created by Australia’s multicultural broadcaster, the Special Broadcasting Service (SBS), an adaptation of Nam Le’s award-winning short story, “The Boat” (2008). SBS’s The Boat (2015) is an immersive online experience that explores a refugee perspective and is accompanied by SBSLearn online learning materials. The Boat (2015) …

Hitting The Jackpot: What Drives Casino Hotel Stock Returns’ Predictability?, Thach Pham, Deepa Bannigidadmath, Edmund Goh, Anna Golab

Research outputs 2022 to 2026

Forecasting casino hotel stock prices are strategically important to key stakeholders making investment decisions. However, there is a paucity of studies that have examined the impact of macro-economic variables, sector-specific variables and firm-specific variables on casino stock returns. This research fills a research gap by examining the predictability of Australian casino hotel stock returns. The forecasting of casino hotel stock prices was modelled using econometric panel predictive regression analysis through the efficacy of 26 predictors comprising macroeconomic variables, sector-specific variables, and firm-specific variables as predictors. All eight casinos listed on the Australia Stock Exchange (ASX) were included in our sample. …

When Descriptor Is Diagnosis: An Autoethnographic Response To The Medical Treatment Of Women With Vulvodynia, Josephine Taylor, Alexandra Ridgway

Research outputs 2022 to 2026

Women with chronic vulvar pain experience symptoms that can affect their everyday functioning. These women are often diagnosed with vulvodynia, defined as vulvar pain without a medical explanation lasting at least three months. Yet while vulvodynia is presented by medical authorities as a diagnosis it is, more accurately, a descriptor of the physical condition. As such it does not have the ability to explain what causes this vulvar pain and, consequently, cannot determine an appropriate treatment pathway for all patients. As women with vulvodynia (‘V women’), we use this article to highlight the issues posed by a descriptor camouflaging as …

Neuromuscular Characteristics Of Eccentric, Concentric And Isometric Contractions Of The Knee Extensors, Cassio V. Ruas, Janet L. Taylor, Christopher Latella, G. Gregory Haff, Kazunori Nosaka

Research outputs 2022 to 2026

Purpose: We compared voluntary drive and corticospinal responses during eccentric (ECC), isometric (ISOM) and concentric (CON) muscle contractions to shed light on neurophysiological mechanisms underpinning the lower voluntary drive in a greater force production in ECC than other contractions.

Methods: Sixteen participants (20–33 years) performed ISOM and isokinetic (30°/s) CON and ECC knee extensor contractions (110°–40° knee flexion) in which electromyographic activity (EMG) was recorded from vastus lateralis. Voluntary activation (VA) was measured during ISOM, CON and ECC maximal voluntary contractions (MVCs). Transcranial magnetic stimulation elicited motor-evoked potentials (MEPs) and corticospinal silent periods (CSP) during MVCs and submaximal (30%) contractions, …

Neurodivergent (Autism And Adhd) Student Experiences Of Access And Inclusion In Higher Education: An Ecological Systems Theory Perspective, Luke Butcher, Stevie Lane

Research outputs 2022 to 2026

Higher Education (HE) can be a complicated and isolating experience for neurodivergent students. Many systemic barriers and injustices create challenges for the accessibility and inclusivity of learning environments and curriculums. However, with the appropriate accommodations, staff guided by neurodiversity-affirming practices, accessible curricula, and opportunities to connect with neurodivergent peers, it can be highly rewarding. Through 15 in-depth, lived-experience-informed interviews with neurodivergent HE students who are Autistic and/or ADHDers in Australia, we analyse experiences at different system levels. By validating the robust framework of ecological systems theory in this context, we extend the academic understanding and add to the limited research …

The Careful Project: Evaluating The Acceptability Of Local Virtual Reality Experiences As A Leisure Activity For Residents In Aged Care, Davina Porock, Patricia Cain, Christopher Young, Julieanne Hilbers, Maria Bomm, Manonita Ghosh, Mandy Stanley

Research outputs 2022 to 2026

Objectives: The aim of this project was to evaluate the feasibility and acceptability of virtual reality (VR) as a leisure activity for people living in residential aged care. Virtual reality experiences may offer alternatives for residents with limited mobility, or during times when older people are unable to leave residential care. Methods: The intervention used VR videos delivered via a head-mounted device. Video content was created by a local artist specifically for use with older Western Australian adults and used local content. VR sessions were videotaped for analysis. The evaluation included structured observation of video content to assess mood and …

Proximity To Cancer Rehabilitation And Exercise Oncology By Geography, Race, And Socioeconomic Status, Kathryn H. Schmitz, Kathryn Demanelis, Mary E. Crisafio, Mary A. Kennedy, Anna L. Schwartz, Anna Campbell, Jessica Gorzelitz, Kelley C. Wood, Christopher M. Wilson, Raymond L. Scalise, Alex Vincent

Research outputs 2022 to 2026

Background: Cancer rehabilitation and exercise oncology (CR/EO) have documented benefits for people living with and beyond cancer. The authors examined proximity to CR/EO programs across the United States with respect to population density, race and ethnicity, socioeconomic status, and cancer incidence and mortality rates.

Methods: This cross-sectional study was conducted in 2022–2023. Online searches were initiated to identify CR/EO programs. Geocoding was used to obtain latitudinal and longitudinal geospatial coordinates. Demographic data were abstracted from the 2020 5-year American Community Survey. Cancer incidence and mortality data were obtained from the Centers for Disease Control and Prevention. US 2013 Rural-Urban Continuum …

Understanding Supervisory Practice And Development In The Pre-Hdr Space: An Ethogenic Approach, Jenny Martin, Alison Owens, Sara Bayes, Paul Tofari, Claire Lynch, Nicola Brown, Benjamin Mountford, Ellen Warne

Research outputs 2022 to 2026

This article addresses the lack of support for new supervisors in the pre-Higher Degree Research space, including undergraduate honours and postgraduate capstone projects. The research provides an inter-faculty perspective on the needs of pre-HDR students and supervisors, informing an online professional learning resource to address the problem. Concepts from ethogenic social psychology were used to theorise supervision as a complex practice involving two analytically distinct domains of human behaviour: the expressive and practical domains. Semi-structured focus group interviews with alumni and supervisors from Education, Arts-Humanities, and Health Sciences provided data for a needs analysis and to stimulate deliberation amongst the …

Career Resources And Securing Quality Work: Graduate Perspectives, Denise Jackson, Claire Lambert, Matalena Tofa, Ruth Bridgstock, Ruth Sibson

Research outputs 2022 to 2026

Empowering graduates to secure quality post-graduation employment is a key goal for higher education institutions and their students. University support in developing career resources may aid transition to work by enhancing social support and networks, fostering a strong sense of professional self, promoting career self-management, and instilling career confidence. Yet there lacks empirical understanding of these resources and the role they play, including how they interrelate, how they vary by personal characteristics, and how they are developed. This study examines how graduates fare in the labour market, characterises their career resources, and explores the relationship between career resources and graduate-level …

Evaluation Of The Sources Of Sexual Knowledge And Information Among Men In Kenya, Darlene Mwende Ndasi, Kwadwo Adusei-Asante, Anh Vo Van Ha, Madalena Grobbelaar, Victor Fannam Nunfam

Research outputs 2022 to 2026

Sources of sexual knowledge and information among men have impact on quality of their sexual literacy and decision making. Sexual knowledge impacts on sexual attitudes, which underpin sexual behaviours and in turn impacts the sexual health outcomes of men. A cross-sectional quantitative survey was used to assess the sources of sexual knowledge and information among 484 Kenyan adult men aged 18–54. Data analysis was performed with STATA-16. Results showed that 79% of men learned about sex from school-based sex education, 75% and 72% from peers and mass media respectively while healthcare professionals (35%) and parents (28%) had the lowest influence …

Doing The Nutbush: How Australia Got Its Very Own Line Dance, Panizza Allmark, Jon Stratton

Research outputs 2022 to 2026

The Nutbush dance is unique to Australia. It is danced to the Ike and Tina Turner track Nutbush City Limits released in 1973. It is a line dance. Anybody can join the line. This article explores the history and reception of the Nutbush. The Nutbush seems have been developed around 1975 in Sydney as a part of modernizing the physical education and creative arts curricula for state primary and secondary schools. The Nutbush is relatively simple and is danced on the beat, a characteristic of dancing to rock music. Nutbush City Limits has a driving beat. This is no doubt …

Artificial Intelligence In Science And Society: The Vision Of Usern, Tommaso Dorigo, Gary D. Brown, Carlo Casonato, Artemi Cerda, Joseph Ciarrochi, Mauro Da Lio, Nicole D'Souza, Nicolas R. Gauger, Steven C. Hayes, Stefan G. Hofmann, Robert Johansson, Marcus Liwicki, Fabien Lotte, Juan J. Nieto, Giulia Olivato, Peter Parnes, George Perry, Alice Plebe, Idupulapati M. Rao, Nima Rezaei, Fredrik Sandin, Andrey Ustyuzhanin, Giorgio Vallortigara, Pietro Vischia, Niloufar Yazdanpanah

All Peer-Reviewed Publications

The recent rise in relevance and diffusion of Artificial Intelligence (AI)-based systems and the increasing number and power of applications of AI methods invites a profound reflection on the impact of these innovative systems on scientific research and society at large. The Universal Scientific Education and Research Network (USERN), an organization that promotes initiatives to support interdisciplinary science and education across borders and actively works to improve science policy, collects here the vision of its Advisory Board members, together with a selection of AI experts, to summarize how we see developments in this exciting technology impacting science and society in …

Biological Control Of Ticks In Domestic Environments: Modeling The Potential Impact Of Entomopathogenic Fungi On The Transmission Of East Coast Fever In Cattle, Joseph Wang Ang A. Oundo, Nienke Hartemink, Mart C.M. De Jong, Constantianus J.M. Koenraadt, Shewit Kalayou, Daniel Masiga, Quirine Ten Bosch

All Peer-Reviewed Publications

Biological control of ticks using entomopathogenic fungi (EPF) is a highly desired alternative to chemical acaricides for the control of tick-borne pathogens. For Metarhizium anisopliae isolate ICIPE 7, one of these EPFs, efficacy against multiple tick species has been demonstrated in laboratory and field settings. However, we currently have little quantitative understanding of how EPFs can impact transmission. We developed a deterministic model of tick–host–pathogen interactions to explore how the effects of EPF on Rhipicephalus appendiculatus ticks may impact the transmission dynamics of East Coast fever (ECF) in cattle populations. We parameterized the multi-faceted effects of EPFs on tick dynamics …

Consequences Of Fire And Grazing To Conservation Of Arthropod Functional Diversity In A Protected Afrotropical Savanna, Ludzula Mukwevho, Tatenda Dalu, Mduduzi Ndlovu, Frank Chidawanyika

All Peer-Reviewed Publications

Fires and grazing disrupt the diversity and composition of biological organisms and their functions in the savannas. In the current study, we assessed the impact of fire and grazing intensities on the abundance, species richness and assemblages of eight functional groups of arthropods in Kruger National Park. Pitfalls and active searches were used to collect arthropods at the experimental burnt plots (EBPs) and grazed plots that were undisturbed, minimally or heavily disturbed in Mopane and Skukuza regions. Omnivores constituted the highest proportion (40 %) of individuals, whilst detritivores, granivores, hematophagous, herbivores, nectarivores, predators and scavengers constituted between 0.5 % and …

Challenges And Lessons From A Vector Control Campaign Targeting Glossina Palpalis Palpalis In An Isolated Protected Forest Area In Abidjan, Côte D’Ivoire, Yao Jean Rodrigue Konan, Bi Tra Dieudonné Ta, Djakaridja Berté, Bamoro Coulibaly, Kinifo Donatien Coulibaly, Nick Steven Egnankon, Foungniguée Diarrassouba, Kouassi Albert Djabo, Stéphanie Watier-Grillot, Jean Paul Demoncheaux, Koffi Alain De Marie Kouadio, Louis N’Dri, Philippe Solano, Sophie Ravel, Guy Pacôme Adingra, Antoine Barreaux, Adeline Ségard, Dramane Kaba, Vincent Jamonneau, Thierry De Meeûs, Vincent Djohan

All Peer-Reviewed Publications

Vector control (VC) is one of the strategies employed to manage African trypanosomoses. This study aimed at assessing the effectiveness of a VC campaign against Glossina palpalis palpalis using tiny targets (TTs) impregnated with insecticide in an isolated, protected forest in Abidjan, Côte d’Ivoire, while considering ecological, genetic, and operational factors. Between January 2020 and September 2022, 2,712 TTs were deployed at 684 sites, covering a total area of 1.7 km2. VC monitoring was conducted using Vavoua traps during 12 evaluation surveys, between June 2020 and March 2023. Five months after the initial TT deployment, tsetse fly density had decreased …

Aflatoxin Prevalence And Association With Maize Grain Physical And Nutritional Qualities In The Informal Markets In Meru County, Kenya, C. Cherotich, M. W. Okoth, Abong’ Go, S. W. Kariuki, E. R. Omuse

All Peer-Reviewed Publications

In Kenya, aflatoxin contamination in maize remains a persistent issue, with potential negative impacts on both public health and economic growth. Aflatoxins are toxic secondary metabolites produced by certain mold species, primarily Aspergillus flavus. The extent of Aspergillus fungal invasion in maize grains and the resulting increase in aflatoxin levels is heavily influenced by pre-and post-harvest practices. Before harvest, factors such as insect damage and exposure to warm, humid conditions increase the crop's susceptibility to Aspergillus infection and subsequent aflatoxin formation. Post-harvest, additional risks arise when kernels are damaged by pests like rats or when they are stored in unfavorable …

Global Strategies To Manage Huanglongbing (Hlb) And Its Vectors: Insights And Implications For The Mediterranean Region, Meritxell Pérez-Hedo, Mark S. Hoddle, Fernando Alferez, Lochy Batista, George A.C. Beattie, Shourish Chakravarty, Paul Holford, Fathiya Mbarak Khamis, Inusa Jacob Ajene, Aruna Manrakhan, Paul H. Fourie, Maritza Luis, Eduardo Osorio-Hernández, Mamoudou Sétamou, Alejandro Tena, Pedro Takao Yamamoto, Tara Wade, Changyong Zhou, Nian Wang, Lukasz L. Stelinski, Alberto Urbaneja

All Peer-Reviewed Publications

Huanglongbing (HLB), also known as citrus greening disease, poses a severe threat to the global citrus industry. This disease is caused by three species of bacteria, ‘Candidatus Liberibacter asiaticus’, ‘C. L. africanus’, and ‘C. L. ameri-canus’. The primary pathogen vectors are the Asian citrus psyllid (Diaphorina citri Kuwayama, Hemiptera: Psyllidae) and the African citrus psyllid (Trioza erytreae Del Guercio, Hemiptera: Triozidae). The disease is incurable, and its management relies on reducing vector densities and the adverse effects of bacterial infections on host trees. Managing psyllid vec-tors, especially D. citri, has proven exceptionally challenging due to its rapid spread and subsequent …

The Relationship Between Brain Perfusion And Structure In Youth With Obesity, With And Without Type 2 Diabetes: A Pilot Study., Ryan P. Brady, Amy S. Shah, Mekibib Altaye, Jacob M. Redel, Dean W. Beebe, Mark W. Difrancesco

Manuscripts, Articles, Book Chapters and Other Papers

Neurocognitive decline, dementia, and stroke are associated with obesity and type 2 diabetes (T2D) in adults. Youth-onset T2D and obesity are occurring more frequently, increasing the risk of earlier onset brain-related morbidity. Emerging evidence has demonstrated global and regional changes in gray matter volume (GMV) and cerebral blood flow (CBF) in youth with T2D and obesity as well. Understanding brain pathophysiology in youth-onset T2D and obesity requires more complex and multi-modal investigation of the brain, such as integration of brain structure and perfusion. Twenty youth with T2D and nineteen age, race, sex, and body mass index (BMI) similar youth with …