Digital Commons Network^™

Uv- Altered Macrophages: Impact Of Uv Radiation On Phagocytic Receptor Expression In M2 Macrophages And Implications For Tissue Repair And Immunosuppression, Hala Hafez

Honors Undergraduate Theses

Ultraviolet radiation is an environmental stressor known to suppress immune function in the skin, but its effect on the immunoregulatory M2 phenotype macrophages is poorly studied. This study aims to investigate the impact of UV exposure on key markers of the M2 macrophage, which are critical for tissue repair and immunosuppression. THP-1 monocytes were differentiated and polarized into the M2 phenotype using Phorbol-12 myristate (PMA) and Cytokines IL-4 and IL-10. Once differentiation was confirmed, the macrophages were exposed to varying durations of UV radiation. Real Time Quantitative PCR was used to analyze expression changes in phagocytic receptors (CD206, CD163, Arg-1), …

The Loneliest Number: Implications For Using Single-Item Measures In Regression Analysis, Juliana Reis

Honors Undergraduate Theses

The current study examines the use of single-item measures to assess constructs used by occupational stress researchers. Surveys are fundamental tools for I/O Psychologist practitioners, and multiple-item measures are commonly used to fulfill that purpose. However, long surveys may offer challenges to both administrators and respondents. As an effort to mitigate those challenges, single-item measures have been receiving recognition as a promising alternative to the current psychometric measures due to their benefits, such as reduced cost and higher face validity. We will discuss the previous studies on single-item measures and why it’s relevant to explore its potential by performing a …

Theoretical Analysis Of Cnns For Automatic Seizure Detection In Eeg Signals, Jackson T. Small

Honors Undergraduate Theses

Epilepsy is a common brain disorder where neurons in the brain rapidly fire, causing recurring seizures. The brain activity during a seizure can be detected by electroencephalogram (EEG) signals; however, this process is not only labor-intensive and time-consuming but is also subject to inter-rater variability, with a study showing only moderate agreement when diagnosing patients, even among experts. Convolutional Neural Networks (CNNs) are often proposed to detect seizures automatically, achieving high performance. The focus on performance comes at a cost of losing interpretability, leaving the model as effective but seen as a ’black box’. This thesis confronts the interpretability knowledge …

Exploring Winnie-The-Pooh For Florida's Resiliency Standards And Social-Emotional Learning Dimensions To Create Literature-Based Activities For The Primary Classroom, Madison R. Simonds

Honors Undergraduate Theses

The intent of this thesis is to examine the intersections between the Florida Resiliency Standards and the social-emotional dimensions established by the Collaborative for Academic, Social, and Emotional Learning (CASEL), as reflected in A. A. Milne’s Winnie-the-Pooh. Through an analysis of key traits within the text, this study explores how children’s literature can serve as an effective tool for fostering social-emotional learning in the primary classroom. By integrating SEL principles with literary instruction, educators can strengthen students’ emotional awareness, interpersonal skills, and resilience. Additionally, this thesis presents a series of instructional activities designed to support teachers in incorporating Winnie …

Resilience As A Protective Factor For Parents Of Young Children With Adverse Childhood Experiences And Socioeconomic Challenges, Hennys Torrealba

Honors Undergraduate Theses

The impact of adverse childhood experiences (ACEs) and socioeconomic challenges can be related to mothers’ and fathers’ ability to parent their children effectively. Subsequently, these factors are related to children’s emotional and behavioral functioning. Children from families who have experienced these challenges are more likely to display behavior problems. Another important factor to consider is parents’ resilience, which can equip parents with the ability to better navigate through challenges. Parents who are resilient can provide a nurturing environment for their children despite challenges and use protective factors (e.g., effective coping strategies) more effectively. The current study examined the relationships among …

Healing Through Art: An Exploration Of Art History Influences On Contemporary Art Therapy For Practices In Oncology Care, Nicole Van

Honors Undergraduate Theses

Art therapy has emerged as a vital practice in oncology, offering patients a means of emotional expression and healing during their treatment journey. This project will explore how integrating art history into therapeutic settings, particularly through virtual classes, enhances the emotional well-being of cancer patients. By examining the impact of engaging with historical artworks, this research aims to illustrate how these artistic narratives can facilitate self-consciousness and foster flexibility in individuals facing significant health challenges. Research indicates that exposure to art can evoke emotion and promote psychological healing, serving as a therapeutic outlet for patients. This study will synthesize therapeutic …

Pediatric Cervical Spine Clearance: A 10-Year Evaluation Of X-Ray In Evaluable Patients At A Level 1 Pediatric Trauma Center, William Starr, Stephanie Iantorno, Jing Wang, Richard Eldredge, Rajiv Iyer, Karch Smith, Natalya Mcnamara, Kezlyn Larsen, Stephen Fenton, Robert Swendiman, Katie Russell

2020-Current year OA Pubs

OBJECTIVES: Cervical spine (c-spine) X-ray (XR) remains an important tool for pediatric trauma patients. XR is a low radiation alternative to multidetector CT (MDCT). Our primary aims were to analyze the sensitivity of a negative c-spine XR and to analyze what factors lead to additional imaging after a negative c-spine XR.

METHODS: A retrospective cohort study was conducted at a level 1 pediatric trauma center from 2012 to 2021. We compared the group with negative c-spine XR and no additional imaging to the group with negative c-spine XR followed by additional c-spine MDCT and/or MRI.

RESULTS: There were 2,081 negative …

Development Of A High-Throughput Platform For Quantitation Of Histone Modifications On A New Qtof Instrument, Emily Zahn, Yixuan Xie, Xingyu Liu, Rashmi Karki, Richard M Searfoss, Francisca N De Luna Vitorino, Joanna K Lempiäinen, Joanna Gongora, Zongtao Lin, Chenfeng Zhao, Zuo-Fei Yuan, Benjamin A Garcia

2020-Current year OA Pubs

Histone post-translational modifications (PTMs) regulate gene expression patterns through epigenetic mechanisms. The five histone proteins (H1, H2A, H2B, H3, and H4) are extensively modified, with over 75 distinct modification types spanning more than 200 sites. Despite strong advances in mass spectrometry (MS)-based approaches, identification and quantification of modified histone peptides remains challenging because of factors, such as isobaric peptides, pseudo-isobaric PTMs, and low stoichiometry of certain marks. Here, we describe the development of a new high-throughput method to identify and quantify over 150 modified histone peptides by LC-MS. Fast gradient microflow liquid chromatography and variable window sequential windows acquisition of …

Accuracy And Reliability Of Video-Based Range-Of-Motion Assessments In Postreconstruction Brachial Plexus Patients, Christopher J. Dy, Stephen J. Demartini, Eshan Sane, David M. Brogan, Planet Study Group

2020-Current year OA Pubs

PURPOSE: Following surgical reconstructions considered successful, many patients with brachial plexus injuries (BPI) have limited limb motion. In addition to manual muscle testing, clinicians typically measure active range of motion (AROM). AROM measurement relies on in-person examination and manual goniometers or visual estimation, both of which are subject to interobserver variability. The purpose of this proof-of-concept study was to evaluate reliability of video-based AROM assessments. We hypothesized that video-based assessment of AROM would have high inter-rater reliability (IRR) among surgeons who perform BPI reconstruction.

METHODS: We video recorded a standardized examination in a convenience sample of 8 postreconstruction BPI patients …

A Clinical Practice Review Of Optimizing The Approach For Correction Of Thoracolumbar Deformity— When And How To Perform Anterior Releases And Fusion, Brian M. Phelps, Munish C. Gupta

2020-Current year OA Pubs

No abstract provided.

Disclosing Disabilities: Barriers For Medical School Applicants, Sarah Leah Solomon, Aitan E. Magence, Harry Haran, Fern R. Juster, Kristina H. Petersen

2020-Current year OA Pubs

This study investigated the availability of accommodation request procedures for medical school admissions interviews and the accessibility of Technical Standards (TS) for candidates with disabilities (CWD) across Liaison Committee on Medical Education (LCME)-accredited institutions in the United States and Canada. Utilizing a cross-sectional study methodology, surveys were distributed to Deans of Admissions and Disabilities Resource Professionals (DRP) at all LCME-accredited US and Canadian MD programs. Surveys gathered data about interview formats, interview accommodation procedures, and TS accessibility during the 2018-2019 academic year. We received responses from 71 institutions (41.3%), with 56.3% survey completion rate (n = 40). Among respondents, interview …

Comparison And Clinical Applicability Analysis Of All-Posterior, Combined Anterior-Posterior, And Combined Lateral-Posterior Approaches In Adult Spinal Deformities: A Narrative Review, Garrison P. Bentz, Christopher Diaz, Nicholas A. Pollatta, Mark J. Lambrechts

2020-Current year OA Pubs

No abstract provided.

Variations In Greater Trochanter Height As A Relation To Patient Demographics: Implications For Femoral Nail Design, Jordan A Haber, Amogh I Iyer, Matthew Dulas, Douglas Weaver, Jason A Strelzow

2020-Current year OA Pubs

Intramedullary nail fixation is the "gold standard" for surgical intervention of femoral fractures. While many aspects of nail design and patient anatomy have received specific focus, anatomic variations in proximal femoral geometry and greater trochanteric height variation have been poorly studied. Understanding the potential relationship of the greater trochanter to patient demographics may provide an opportunity to improve implant placement. Retrospective review of x-ray and computed tomography images of the proximal femur was performed. Inclusion criteria consisted of skeletally mature patients over 18 years old with imaging of the proximal femur. Inclusion criteria identified 296 patients. Mean age of included …

Physical Activity As A Resistance Or Resilience Mechanism In Down Syndrome Alzheimer's Disease, Victoria L Fleming, Beau M Ances, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Adults with Down syndrome (DS) are at risk for Alzheimer's disease (AD). Lifestyle factors such as engagement in moderate-to-vigorous physical activity (MVPA) reduce risk or delay the onset of AD. This study aimed to determine whether MVPA confers a

METHODS: Analyses included 69 adults with DS (aged 26-58) who participated in a longitudinal study across 3.29 years. An actigraphy accelerometer assessed MVPA across 7 days. Directly administered and informant-reported measures assessed cognitive functioning, specifically memory and dementia symptoms. Neuroimaging biomarkers quantified amyloid beta (Aβ) burden, as assessed via positron emission tomography imaging.

RESULTS: In regression models, baseline MVPA was …

Pfedrag: A Personalized Federated Retrieval-Augmented Generation System With Depth-Adaptive Tiered Embedding Tuning, Hangyu He, Xin Yuan, Kai Wu, Ren Ping Liu, Wei Ni

Research outputs 2022 to 2026

Large Language Models (LLMs) can undergo hallucinations in specialized domains, and standard Retrieval-Augmented Generation (RAG) often falters due to general-purpose embeddings ill-suited for domain-specific terminology. Though domain-specific fine-tuning enhances retrieval, centralizing data introduces privacy risks. The use of federated learning (FL) can alleviate this to some extent, but faces challenges of data heterogeneity, poor personalization, and expensive training data generation. We propose pFedRAG, a novel Personalized Federated RAG framework, which enables efficient collaborative fine-tuning of embedding models to address these challenges. The key contribution is a new Depth-Adaptive Tiered Embedding (DATE) architecture, which comprises a Global Shared Layer, combined using …

The Dark Side Of International Cooperation: Indifference And The Psychosocial Dynamics Of Cooperative Deterrence, Jamal Barnes

Research outputs 2022 to 2026

States are increasingly resorting to international cooperative agreements to deter migrants and refugees from irregularly arriving at their borders. Although scholars have shown how these cooperative deterrence policies are undermining important refugee and human rights protections, making migration journeys more dangerous, and securitizing and criminalizing people on the move, what has not been adequately examined is how these cooperative arrangements can bring about normative changes that produce indifference to the suffering of refugees and migrants. This article examines the psychosocial dynamics of cooperative deterrence policies to show how the social processes of authorization, routinization, evasion of responsibility, and dehumanization weaken …

Improving Hpv Vaccine Rates For Aboriginal Young People Through A Social Media Campaign: An Interrupted Time Series, Natalie A. Strobel, Jocelyn Jones, Kim Gates, Simon L. Turner, Joanne E. Mckenzie, Daniel R. Mcaullay

Research outputs 2022 to 2026

Human papillomavirus (HPV) is a common sexually transmitted infection that can lead to HPV-related cancers such as cervical cancer and other cancers such as anal, vaginal, and penile cancer. HPV rarely produces symptoms and cannot be cured or treated; therefore, vaccination is essential to protect against HPV and HPV-related diseases. However, young Aboriginal and Torres Strait Islander (hereafter, respectfully, ‘Aboriginal’) people are not receiving their HPV vaccine dose, resulting in missed opportunities to be protected from HPV-related cancers. Health promotion is a critical way to empower people to take ownership over and control their health and is a core function …

Fashioning Intangible Cultural Heritage In Tourism, Chaowu Xie, Hai Zhu, Jiangchi Zhang, Songshan Huang

Research outputs 2022 to 2026

The fashion evolution of intangible cultural heritage in tourist destinations is vital for promoting intangible cultural heritage inheritance and innovation. However, there is limited literature on its specific manifestations and influencing factors. This study employed a mixed research design. Study 1, taking Xunpu head-pinned flowers decoration as a study case, and following grounded analysis, found that the fashion evolution of intangible cultural heritage in tourist destinations was manifested by the pattern of “traditional ontology evolving into fashion ontology, traditional representations evolving into fashion representations, and traditional constructions evolving into fashion constructions.” Study 2, based on a scenario-based experiment, found that …

Everyday Sexisms Take Away Tote Bags: Tools For Communicating Research Findings, Mindy Blaise, Emily M. Gray, Jacqueline Ullman, Emma Fishwick

Research outputs 2022 to 2026

In 2023 Takeaway Tote Bags bags were created and handed out to delegates attending an Australian national educational research conference. Usually conference bags are filled with corporate sponsored freebies like branded pens, notepads, and water bottles. The Everyday Sexisms Takeaway Tote Bags were different because they were conceptualised as a tool for creatively communicating research findings from a national mixed-methods research project about everyday sexisms in Australian Universities to a broad audience. Several resources were developed to open- up opportunities for dialogue, reflection, and pathways to action.

Fostering An Inclusive And Sustainable Career Ecosystem: Empowering Neurodivergent Individuals And Employees To Thrive, William E. Donald, Elizabeth J. Cook, Nimmi P. Mohandas

Research outputs 2022 to 2026

Purpose: This article synthesises contributions from the special issue “Fostering an inclusive and sustainable career ecosystem: empowering neurodivergent individuals and employees to thrive”. It reframes neurodivergence as a source of strength, while acknowledging the complex interplay between strengths and systemic challenges. The article advocates for evidence-informed strategies that promote inclusive and sustainable career pathways, emphasising the interaction between individual agency and structural change rather than commodifying neurodivergent talent as “superpowers”.

Design/methodology/approach: Guided by the sustainable career ecosystem theory, this article identifies five key principles derived from the nine contributions spanning four continents and seven countries. These principles are examined in …

Entrepreneurship: A Practical Guide For Business Success, Jalleh Sharafizad, Violetta Wilk, Kerry Brown, Aglae Hernandez Grande, Fleur Sharafizad, Dorothy Wardale

Research outputs 2022 to 2026

This book is tailored for entrepreneurs in their startups or moving to the next stage of their businesses, micro and small business owners, as well as individuals who are considering starting their own ventures. It brings together essential insights, practical tools, and valuable resources developed through two Western Australian government initiatives focused on entrepreneurial training and support. In addition, it draws on a range of business concepts from other sources, refining and simplifying them to suit the specific needs of emerging and growing enterprises.

Designed to be both flexible and supportive, the book serves multiple roles throughout your entrepreneurial journey. …

Mill Power Consumption And Fuel Particle Size Distribution While Co-Milling Bituminous Coal With Steam-Exploded Woody Biomass In A Conventional Bowl Mill, Brian Schoof, Rajarshi Roy, Regan Kuttler, Parker Latour, Scott Montgomery, Jacob Tuttle, Gwendolyn Bennett Bennett, Brian D. Iverson, Andrew Fry

Faculty Publications

The mill behavior of a 312 Combustion Engineering Raymond Bowl Mill was studied with five blends of Utah bituminous coal and steam-exploded woody biomass, ranging from 100 % coal to 100 % biomass. Mill power consumption increased with biomass content, peaking at 187 % of the power required for 100 % coal before the mill faulted at 100 % biomass. After repositioning the rollers, power consumption for 100 % biomass decreased by 13 % compared to 100 % coal. SEM images revealed that milled biomass particles were non-spherical, indicating some fibrous structure remained post steam-explosion. The particle size distribution (PSD) …

Drop Dynamics During Condensation On Superhydrophobic Surfaces In Vapor Shear Flow, Shaur Humayun, R. Daniel Maynes, Julie Crockett, Brian D. Iverson

Faculty Publications

Accurate models for predicting drop dynamics, such as maximum drop departure sizes, are crucial for estimating heat transfer rates during condensation on superhydrophobic (SH) surfaces. Previous studies have focused on examining the heat transfer rates for SH surfaces under the influence of gravity or vapor flowing over the surface. This study investigates the impact of surface solid fraction and texture scale on drop mobility in a condensing environment with a humid air flow. Experiments recorded condensation with varying surface feature sizes from micro- to nano scale under different flow rates. Video analysis detected the drop-size distribution and maximum drop departure …

The Petrology And Geochemistry Of The Montagna Grande-Monte Gibele Trachytic Shield Volcano (Pantelleria, Italy)., John C. White, Ray Macdonald, Pierangelo Romano, Boguslaw Baginski, Silvio G. Rotolo, Beata Marciniak-Maliszewska, Alessandra Cinquegrani

EKU Faculty and Staff Scholarship

The 45.7 ± 1.0 ka (2σ) eruption of the compositionally zoned (comenditic trachyte to pantellerite) Green Tuff ignimbrite on the volcanic island of Pantelleria, Italy, was followed by the extrusion of a series of post-caldera metaluminous to mildly peralkaline trachyte lavas between 26.2 ± 2.0 and 22.3 ± 2.9 ka (2σ). This study uses whole-rock major- and trace-element compositions, mineral compositions, geothermobarometry, and petrogenetic models to examine the role of trachytes in the evolution of the Pantelleria magma system. Although previous studies have suggested that all of these units are consanguineous and form a liquid line of descent (LLOD) from …

When They See Us: The Lived Experiences Of Bglo Members At A Pwi, Brittany Harris-Nelson

Theses and Dissertations

This applied dissertation explored the lived experiences of members of Black Greek-Letter Organizations (BGLOs) at a predominantly White institution (PWI) in the years following the COVID-19 pandemic. BGLOs have historically served as critical spaces for leadership development, cultural expression, and community support. However, within PWIs, these organizations often encounter systemic barriers related to visibility, funding, and institutional engagement.

The purpose of this study was to center the voices of BGLO alumni who graduated between 2020 and 2024 to better understand how they navigated their membership experiences during a time of social, institutional, and cultural transition. Using a qualitative research design, …

Certain Knowledge Of Administrative Decisions Issued By Artificial Intelligence Systems In The Public Sector: A Comparative Analysis, Nayel Musa Alomran, Odai Mohammad Alheilat

All Works

This paper aims to elucidate the matter of certain knowledge pertaining to administrative decisions, those issued by artificial intelligence. It also clarifies the position of the administrative judiciary with regard to the adoption of this presumption and through a comparative analysis of administrative judicial applications in Jor-dan, Egypt, and Morocco. The text addresses the most significant evidence for achieving certain knowledge of an administrative decision – and thereby initiating the appeal period against the appellant. The question at hand is whether the administrative judiciary applies the traditional theory of certain knowledge to its counterpart issued by artificial intelligence systems, especially …

Exploring Biostimulant Efficacy Under Limited Fertilizer And Water In Utah's Watermelon Production, Evan Christensen, Milena Oliveira, Prakriti Nepal, Youping Sun

Plants, Soils and Climate Student Research

The western U.S. has recently experienced some of the driest conditions on record, and Utah has been in a multi-year drought (2019-2023) that affected the agricultural sector, including vegetable producers. While vegetables are not a primary agricultural crop in Utah, they are still an important part of the horticultural economy with 763 farms growing 6,138 acres. As the fourth largest acreage vegetable crop in Utah (almost 10% of the acreage) watermelon and related crops in the gourd family Cucurbitaceae (nearly 36% of total vegetable acreage) are important to vegetable growers. Watermelon is a water-intensive crop and requires an adequate supply …

Quality Of Life Among Indonesian Family Caregivers Caring For Dependent Older Persons With Type 2 Diabetes Mellitus In The Community: A Cross-Sectional, Correlational Study, Rinco Siregar, Charuwan Kritpracha, Tippamas Chinnawong, Jos M. Latour

School of Nursing and Midwifery

Background: The global prevalence of older adults with diabetes has increased, and family caregivers in Indonesia play a critical role in managing diabetes and providing personal care. However, caregiving can be complex and challenging, often negatively affecting caregivers' quality of life (QoL). Objective: This study aimed to develop and test a hypothesized causal model of QoL among Indonesian family caregivers who care for dependent older persons with type 2 diabetes mellitus (T2DM) in 2024. Methods: A cross-sectional, correlational study was conducted with 270 family caregivers recruited from five Community Health Centers. Data were collected using various scales: the Center for …

‘The Transition Home With A Premature Baby’: How Prepared Are Parents For Discharge From Nicu: A Narrative Review, Beth Taylor, Kevin Hambridge

School of Nursing and Midwifery

Aims: To systematically review qualitative studies, investigating how prepared parents are for discharge home from NICU with their premature baby. Design: A qualitative narrative review and thematic synthesis of selected qualitative research evidence. Data sources: Searches were found between December 2022 and March 2023. Electronic databases (CINAHL, PsycINFO, PUBMED, Science Direct) were used. Additionally, Google Scholar for grey literature. Studies were searched within the ten-year time frame. Review methods: Seven primary studies met the inclusion criteria and were appraised for quality using the Critical Appraisal Skills Program tool. Qualitative data was collected, therefore creating a thematic synthesis. Results: Seven qualitative …

From Myriad To Moderna: The Modern (Bio)Pharmaceutical Company, Ana Santos Rutschman

Faculty Publications

This Article examines the emergence of two modern pharmaceutical companies: Myriad and Moderna. After providing a brief background on each company, this Article contrasts them across the following areas: the technologies they have brought to market; their location; their start-up stages and the role that venture capital played in catalyzing their evolution from start-ups to large corporate structures; their relationships with other entities in the private sector, in academia and in the public sector; and their intellectual property and licensing strategies.