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A Unifying Double-Reference Approach To Semantic Paradoxes: From The White-Horse-Not-Horse Paradox And The Ultimate-Unspeakable Paradox To The Liar Paradox In View Of The Principle Of Noncontradiction, Bo Mou Jan 2025

A Unifying Double-Reference Approach To Semantic Paradoxes: From The White-Horse-Not-Horse Paradox And The Ultimate-Unspeakable Paradox To The Liar Paradox In View Of The Principle Of Noncontradiction, Bo Mou

Faculty Research, Scholarly, and Creative Activity

The purpose of this study is to suggest and explain an engaging approach to three distinct types of (alleged or genuine) semantic paradoxes, the White-Horse-Not-Horse Paradox, the Ultimate-Unspeakable Paradox, and the Liar Paradox, in a unifying way that is sensitive to distinct features of them. Although the three types of semantic paradoxes address distinct types of objects, and although their seemingly paradoxical features are different (alleged or genuine), their distinct structures and contents can be understood and treated on the same common ground, which is jointly conceived in people's pretheoretic understandings of truth and of the double-reference feature of people's …

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Leukocyte Infiltration Profiles At The Site Of Intradermal Injection Of Silikon-1000 In Scleroderma-Prone Ucd200/206 And Healthy White Leghorn Chickens, Katee L. Johnson, Jossie M. Santamaria, Chrysta N. Beck, Gisela F. Erf Jan 2025

Leukocyte Infiltration Profiles At The Site Of Intradermal Injection Of Silikon-1000 In Scleroderma-Prone Ucd200/206 And Healthy White Leghorn Chickens, Katee L. Johnson, Jossie M. Santamaria, Chrysta N. Beck, Gisela F. Erf

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Intradermal injections of silicone-based fillers for the face and body may cause chronic inflammation and fibrotic reactions in some individuals. Chickens from the UCD 200/206 White Leghorn (WL) line spontaneously develop a fibrotic autoimmune disease known as scleroderma/systemic sclerosis (SSc). Using the SSc-prone UCD and healthy WL chickens, a longitudinal study was conducted to examine the cellular inflammatory responses to intradermal (i.d.) injections of sterile SILIKON-1000. Specifically, the pulp (a skin derivative) of growing feathers (GFs) was i.d. injected with sterile SILIKON-1000 or phosphate-buffered saline (PBS) as injection control (8 and 3 birds/line, respectively; 10 µL/GF; 20 GFs/bird). Two GFs …

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Differences In Cellular And Humoral Immune Responses To A Primary And Secondary Immunization With Herpesvirus Of Turkey (Hvt) Vaccine In Layer Pullets, Allie K. Bowerman, Chrysta N. Beck, Jossie M. Santamaria, Gisela F. Erf Jan 2025

Differences In Cellular And Humoral Immune Responses To A Primary And Secondary Immunization With Herpesvirus Of Turkey (Hvt) Vaccine In Layer Pullets, Allie K. Bowerman, Chrysta N. Beck, Jossie M. Santamaria, Gisela F. Erf

2025 Research Poster Competition

In poultry production, chickens are routinely vaccinated with live herpesvirus vaccines for protection from lymphoma causing Marek’s disease virus. However, information on the immune responses to these vaccines is limited. This study examined cellular and antibody responses to primary and secondary vaccinations with herpesvirus of turkey (HVT). Six unvaccinated 9-wk-old, and six HVT-vaccinated (s.c. at hatch) 19-wk-old, layer pullets received a first (V1) or a second (V2) HVT vaccination, respectively, by intradermal injection of HVT-vaccine into the pulp of growing feathers (GFs; 10 µL/GF; 16 GFs/bird). GFs were collected before (0h), and at 0.25, 1, 2, 3, 5, 7, and …

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Collective Liberation Through Critical Pedagogy, Robert A. Marx, Anne E. Dufault, Miriam R. Arbeit Jan 2025

Collective Liberation Through Critical Pedagogy, Robert A. Marx, Anne E. Dufault, Miriam R. Arbeit

Faculty Research, Scholarly, and Creative Activity

The collective liberation of queer and trans people—which is inherently tied to the liberation of those oppressed by white supremacy and racism, ableism, classism, ageism, and other asymmetrical power distributions—is possible when we develop critical consciousness through critical pedagogy. As young people develop an awareness of the contradictions and falsehoods they are taught (e.g., the myth of meritocracy), they begin to work to change their environments and offer resistance to the structures that inequitably shape their world. The vast majority of research on queer and trans adolescents, though, has been shaped by dominant, deficit-based views of queerness that presuppose that …

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Young Audience And Vod Platforms Of Linear Television. Perceptions About Playz, Mtmad And Flooxer, Belén Moreno Albarracín, Tania Blanco Sánchez Jan 2025

Young Audience And Vod Platforms Of Linear Television. Perceptions About Playz, Mtmad And Flooxer, Belén Moreno Albarracín, Tania Blanco Sánchez

Faculty Research, Scholarly, and Creative Activity

Introduction: The new audiovisual paradigm, marked by flexible consumption, a wide catalog and a participatory audience, increases the interest of linear television in connecting with young people. To that end, the channels manage specialized content platforms. This research aims to analyze Mtmad, Playz and Flooxer, and the perceptions about them. The specific objectives are to examine the catalogs; evaluate identification with management chains; analyze youth-content identification and study their consumption habits. Methodology: A content analysis based on web structures and catalogs is proposed; and a survey of 160 young people about their knowledge, identification and consumption patterns. Results: Mtmad leads …

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Temporal Patterns Of The Introduced Sponge Hymeniacidon Perlevis (Montagu, 1814) In The Elkhorn Slough, California, Usa, Jackson T. Hoeke, Kerstin Wasson, Amanda S. Kahn Jan 2025

Temporal Patterns Of The Introduced Sponge Hymeniacidon Perlevis (Montagu, 1814) In The Elkhorn Slough, California, Usa, Jackson T. Hoeke, Kerstin Wasson, Amanda S. Kahn

Faculty Research, Scholarly, and Creative Activity

Hymeniacidon perlevis is a cosmopolitan sponge with a seasonal life cycle. We investigated seasonal and interannual dynamics of H. perlevis in Elkhorn Slough estuary, where it is an introduced species, and explored correlations between sponge cover and environmental conditions. We used sponge cover to estimate the potential effects of H. perlevis on its environment, and how those could vary across its seasonal life cycle. We found that recruitment is currently restricted to the upper estuary and while it varies annually, the frequency and density of sponge recruits have generally increased from 2007 to 2023. A seasonal life cycle was confirmed …

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Learning About The Transit Passenger Experience From Microblogging Posts, Egbe Etu Etu, Asha Weinstein Agrawal, Jordan Larot, Chaitanya Tatipigari, Imokhai Theophilus Tenebe Jan 2025

Learning About The Transit Passenger Experience From Microblogging Posts, Egbe Etu Etu, Asha Weinstein Agrawal, Jordan Larot, Chaitanya Tatipigari, Imokhai Theophilus Tenebe

Faculty Research, Scholarly, and Creative Activity

Transit agencies often track delays and malfunctions but may overlook riders’ real-time social experiences. To fill this gap, we analyzed 559 tweets from 2020 to 2023 that captured personal accounts of public transport use. Using thematic analysis, we found that 74% of posts criticized other passengers’ behavior, far outweighing comments on transit ride quality, such as complaints about delays (25%). Notably, 86% of tweets expressed negative sentiment, though some highlighted exceptional service. These findings demonstrate that interpersonal dynamics are a key contributor to riders’ experiences and illustrate the nature of the interactions that riders like and dislike.

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Evaluating Seasonal Vs. Spatial Extrapolation For Cetacean Distribution Models In The California Current, Elizabeth A. Becker, Karin A. Forney, Bruce J. Thayre, Katherine Whitaker, Ryan Hoopes, Joshua M. Jones, John A. Hildebrand, Jeff Moore Jan 2025

Evaluating Seasonal Vs. Spatial Extrapolation For Cetacean Distribution Models In The California Current, Elizabeth A. Becker, Karin A. Forney, Bruce J. Thayre, Katherine Whitaker, Ryan Hoopes, Joshua M. Jones, John A. Hildebrand, Jeff Moore

Faculty Research, Scholarly, and Creative Activity

Species distribution models (SDMs) have been developed for multiple cetacean species within the California Current Ecosystem (CCE) from shipboard survey data collected by the Southwest Fisheries Science Center (SWFSC) in summer and fall, thus limiting the ability to inform management decisions in cool seasons when abundance and distribution patterns are substantially different. Winter and spring SDMs have been developed for a few species using California Cooperative Oceanic Fisheries Investigations (CalCOFI) shipboard survey data, but model predictions are limited to the waters off southern and central California. In this study, winter and spring density estimates for the entire CCE study area …

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Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor Jan 2025

Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor

Faculty Publications

This paper presents CoNaV, a comprehensive framework for creating a multi-vehicle cooperative localization (CL) testbed designed to support the benchmarking, development, and deployment of cooperative navigation algorithms. Given the essential role of CL in improving localization accuracy for both defense and civilian applications, CoNaV provides a robust environment for rigorously validating algorithms under real-world conditions. By establishing a benchmark for CL algorithms, CoNaV lays a foundation for advancing research into more sophisticated and distributed CL solutions. This framework highlights the potential of cooperative navigation to enhance multi-vehicle operations and offers a scalable, practical approach for future developments in CL technology.

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From Shocks To Solidarity And Superstition: Exploring The Foundations Of Faith, Aidin Hajikhameneh, Laurence R. Iannaccone Jan 2025

From Shocks To Solidarity And Superstition: Exploring The Foundations Of Faith, Aidin Hajikhameneh, Laurence R. Iannaccone

Faculty Research, Scholarly, and Creative Activity

Additive shocks can substantially increase cooperation in otherwise standard public goods game experiments. We study shocks that randomly adjust players’ earnings by a fixed positive or negative amount reported at the end of each round. These adjustments change neither the return to players’ contributions nor the information about other group members. We compare results across four treatments that employ the same group-level adjustment algorithm but frame it differently, with pre-play descriptions that range from omitting all useful information to accurately revealing its 50/50 random nature. In each treatment, overall contributions run about 50% higher than those obtained in the standard …

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How We Could Have Libertarian Free Will Even If God Were A Total Know-It-All About The Future, Mark Balaguer, Rebecca Chan Jan 2025

How We Could Have Libertarian Free Will Even If God Were A Total Know-It-All About The Future, Mark Balaguer, Rebecca Chan

Faculty Research, Scholarly, and Creative Activity

We argue that libertarianism (roughly, the thesis that we have indeterministic, libertarian free will) is compatible with God's infallible foreknowledge. We use eternalism (roughly, the thesis that reality is a 4-dimensional block and that past, present, and future objects exist) as an explanatory stepping stone between libertarianism and God's foreknowledge: eternalism entails that (and comes close to explaining how) an omniscient God would know what we decide in the future even if we have libertarian free will. This account also explains what is wrong with standard fatalist arguments for the incompatibility of free will and God's foreknowledge.

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On Modeling Agent Behavior Change Through Multi-Typed Information Diffusion In Online Social Networks, Masaaki Miyashita, Norihiko Shinomiya, Daisuke Kasamatsu, Genya Ishigaki Jan 2025

On Modeling Agent Behavior Change Through Multi-Typed Information Diffusion In Online Social Networks, Masaaki Miyashita, Norihiko Shinomiya, Daisuke Kasamatsu, Genya Ishigaki

Faculty Research, Scholarly, and Creative Activity

The rapid spread of information on online social networks (OSNs) has had both beneficial and detrimental societal impacts. Notably, the propagation of misinformation during events such as the COVID-19 pandemic has driven collective behavioral responses, sometimes exacerbating crises such as panic buying and bank runs. The toilet paper shortage in Japan in 2020 caused by people's selfish behavior owing to the diffusion of information to correct misinformation, which is considered a general phenomenon based on three sociological characteristics: a collective action problem, a self-fulfilling prophecy, and pluralistic ignorance. Understanding what kind and how information can inhibit selfish behavior to mitigate …

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Physiological Effects Of Research Handling On The Northern Elephant Seal (Mirounga Angustirostris), Lauren A. Cooley, Allyson G. Hindle, Cassondra L. Williams, Paul J. Ponganis, Shawn M. Hannah, Holger Klinck, Markus Horning, Daniel P. Costa, Rachel R. Holser, Daniel E. Crocker, Birgitte I. Mcdonald Jan 2025

Physiological Effects Of Research Handling On The Northern Elephant Seal (Mirounga Angustirostris), Lauren A. Cooley, Allyson G. Hindle, Cassondra L. Williams, Paul J. Ponganis, Shawn M. Hannah, Holger Klinck, Markus Horning, Daniel P. Costa, Rachel R. Holser, Daniel E. Crocker, Birgitte I. Mcdonald

Faculty Research, Scholarly, and Creative Activity

Wildlife researchers must balance the need to safely capture and handle their study animals to sample tissues, collect morphological measurements, and attach dataloggers while ensuring their results are not confounded by stress artifacts caused by handling. To determine the physiological effects of research activities including chemical immobilization, transport, instrumentation with biologgers, and overnight holding on a model marine mammal species, we collected hormone, blood chemistry, hematology, and heart rate data from 19 juvenile northern elephant seals (Mirounga angustirostris) throughout a translocation experiment. Across our six sampling timepoints, cortisol and aldosterone data revealed a moderate hormonal stress response to handling accompanied …

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The Multiple Classes Of Ultra-Diffuse Galaxies: Can We Tell Them Apart?, Maria Luisa Buzzo, Duncan A. Forbes, Thomas H. Jarrett, Francine R. Marleau, Pierre Alain Duc, Jean P. Brodie, Aaron J. Romanowsky, Anna Ferré-Mateu, Michael Hilker, Jonah S. Gannon, Joel Pfeffer, Lydia Haacke Jan 2025

The Multiple Classes Of Ultra-Diffuse Galaxies: Can We Tell Them Apart?, Maria Luisa Buzzo, Duncan A. Forbes, Thomas H. Jarrett, Francine R. Marleau, Pierre Alain Duc, Jean P. Brodie, Aaron J. Romanowsky, Anna Ferré-Mateu, Michael Hilker, Jonah S. Gannon, Joel Pfeffer, Lydia Haacke

Faculty Research, Scholarly, and Creative Activity

This study compiles stellar populations and internal properties of ultra-diffuse galaxies (UDGs) to highlight correlations with their local environment, globular cluster (GC) richness, and star formation histories. Complementing our sample of 88 UDGs, we include 36 low surface brightness dwarf galaxies with UDG-like properties, referred to as NUDGes (nearly UDGs). All galaxies were studied using the same spectral energy distribution fitting methodology to explore what sets UDGs apart from other galaxies. We show that NUDGes are similar to UDGs in all properties except for being, by definition, smaller and having higher surface brightness. We find that UDGs and NUDGes show …

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Town And Country Garden Club Papers - Accession 1434, Garden Club, Town And Country Jan 2025

Town And Country Garden Club Papers - Accession 1434, Garden Club, Town And Country

Manuscript Collection

The Town and Country Garden Club Papers includes photographs from various club events, newspaper clippings, awards and descriptions of Awards, and yearly member packets containing the names of members, monthly meetings and socials, by-laws, constitution and various information.

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Impact Of Bundled Care: Optimizing Pain Management Outcomes In Acute Care, Mary Kelly, Denise Danna, Marsha Bennett, Karen Rice, Helen Calmes, Paige Fisher, Mary Dioise Ramos Jan 2025

Impact Of Bundled Care: Optimizing Pain Management Outcomes In Acute Care, Mary Kelly, Denise Danna, Marsha Bennett, Karen Rice, Helen Calmes, Paige Fisher, Mary Dioise Ramos

School of Nursing Faculty Publications

Purpose: Despite therapeutic advances, inadequate pain management in hospitalized patients often leads to chronic pain and opioid dependency. Nonpharmacologic strategies offer potential benefits, especially when integrated into a bundled care approach that enhances pain management and patient engagement. This research aimed to test the effect of a standardized bundle of evidence-based pain care strategies on medical-surgical patients' perceived pain quality outcomes. Design & Methods: This study employed a 2-group, quasi-experimental design to assess the impact of a unit-based intervention, PAIN-X Therapy, on pain care quality outcomes compared to usual pain care. Results: There were 365 participants included in the study …

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Annual Fire Safety Report, 2024, Illinois State University, Environmental Health And Safety Jan 2025

Annual Fire Safety Report, 2024, Illinois State University, Environmental Health And Safety

Fire Safety Annual Reports

The Higher Education Opportunity Act (HEOA) requires all institutions of higher education that provide residential housing facilities for students to develop an annual fire safety report. Elements of Illinois State University’s campus fire safety program consists of: fire prevention policies and practices, fire safety educational and training initiatives, description of fire protection equipment in the residence halls, emergency evacuation procedures, fire safety statistics, and plans for future improvements to the residence hall campus fire safety program. The annual fire safety report summarizes the elements of the campus fire safety program, which is administered and maintained by Environmental Health and Safety …

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The Association Of Social Determinants Of Health And Type Ii Diabetes Self-Management Among Persons Living With Physical Disability (Mobility & Visual Impairments), Anita Aboagye Jan 2025

The Association Of Social Determinants Of Health And Type Ii Diabetes Self-Management Among Persons Living With Physical Disability (Mobility & Visual Impairments), Anita Aboagye

All ETDs from UAB

Type II Diabetes (T2D) management yield positive outcomes in glycemic control, lifestyle behaviors, knowledge enhancement, and self-care. Persons with disability (PWDs) - regardless of disability type - are faced with additional challenges in diabetes self- management. Moreover, PWDs exhibit adverse outcomes across various measures of social determinants of health (SDOH) compared to individuals without disabilities. This dissertation explored four research aims to examine the impact of adverse SDOH experiences on T2D self- management among persons with physical disability utilizing a preprint/reprint format - with each aim leading to a manuscript. Secondary data analysis using the 2022 Behavioral Risk Factor Surveillance …

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Numerical Analysis And The Deal.Ii Implementation Of An Efficient And Robust Parameterized Ensemble Algorithm For Navier Stokes Flow In The Convection-Dominated Regimes, Brandiece Berry Jan 2025

Numerical Analysis And The Deal.Ii Implementation Of An Efficient And Robust Parameterized Ensemble Algorithm For Navier Stokes Flow In The Convection-Dominated Regimes, Brandiece Berry

All ETDs from UAB

Ensemble methods are widely used to approximate solutions for the Navier-Stokes Equations to account for inherent uncertainties within the system. This work goes about the numerical analysis and efficiency assessment of a fully discretized Ensemble Eddy Viscosity (EEV) model for the incompressible Stochastic Navier-Stokes Equations. The model is efficient due to the use of ensemble methods. Through a single coefficient matrix for $J$ realizations, we reduce computational cost and thereby ensure computational efficiency. It is found that the model is robust with the inclusion of the eddy viscosity term, as an additional uncertainty quantification. Finally, we verify theoretical convergence rates …

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Wear Resistance Of 3d Printed Occlusal Splint Materials, Pierpont Flanders Brown Jan 2025

Wear Resistance Of 3d Printed Occlusal Splint Materials, Pierpont Flanders Brown

All ETDs from UAB

Statement of problem: Three-dimensional (3D) printing offers an efficient method to produce occlusal devices (splints). However, their wear resistance is poorly understood. Purpose: The purpose of this in vitro study was to compare the wear resistance of flexible and rigid 3D printed occlusal splint materials to milled and conventionally processed occlusal splint materials. By establishing such a comparison, this study will help provide clinicians with greater knowledge of which materials and methods will provide their patients with the most wear resistant and durable occlusal splint possible. Material and methods: Identical sized blocks (n=8) of 3 flexible 3D printed materials (KeySplint …

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Reelin Regulation Of Striatal Physiology And Cocaine Reward, Kasey Lynn Brida Jan 2025

Reelin Regulation Of Striatal Physiology And Cocaine Reward, Kasey Lynn Brida

All ETDs from UAB

Drugs of abuse activate defined neuronal populations in brain reward structures such as the nucleus accumbens (NAc), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. While the molecular and cellular effects arising from experience with drugs like cocaine are increasingly well understood, the mechanisms that sculpt NAc neuron participation are largely unknown. Here, we leveraged unbiased single-nucleus transcriptional profiling to identify expression of the secreted glycoprotein Reelin (encoded by the Reln gene) as a marker of cocaine-activated neurons within the rat NAc. Multiplexed in situ detection confirmed selective expression of the immediate early …

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Food Insecurity Among Graduate Students At The University Of Alabama At Birmingham, Amy Elizabeth Callahan Jan 2025

Food Insecurity Among Graduate Students At The University Of Alabama At Birmingham, Amy Elizabeth Callahan

All ETDs from UAB

College food insecurity (FI) has grown steadily as a field of research over the past fifteen years. Existing research primarily has demonstrated that FI is a persistent problem with various risk factors and myriad potential impacts on students, though graduate students are largely understudied in favor of undergraduate and aggregated student populations. Given the unique circumstances graduate students face, as well as expected demographic differences such as age and household characteristics, this is a serious gap in the literature. This dissertation aims to investigate graduate student food insecurity in the United States, and particularly at the University of Alabama at …

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Platal Expansion Using The Invisalign Palatal Expander "Ipe", Hassan Chihab Jan 2025

Platal Expansion Using The Invisalign Palatal Expander "Ipe", Hassan Chihab

All ETDs from UAB

Palatal expansion has been used in orthodontics to treat a narrow maxilla and to primarily correct posterior dental crossbites. In younger patients, palatal expansion can readily be achieved through opening of the mid-palatal suture, as it is not fused at that age. As the mid-palatal suture matures, expansion will gradually be difficult to achieve, and more dental expansion is obtained rather than skeletal. In addition, there is a tendency to get more dental tipping. Palatal expansion has been recommended not only to correct crossbites but also to improve breathing in patients with sleep disorders such as obstructive sleep apnea (OSA). …

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Co-Creating A Social, Emotional, And Mental Health Well-Being Group For College Students With Disabilities And/Or Chronic Health Conditions And Are Registered With Disability Support Services, Consuelo A. Click Copeland Jan 2025

Co-Creating A Social, Emotional, And Mental Health Well-Being Group For College Students With Disabilities And/Or Chronic Health Conditions And Are Registered With Disability Support Services, Consuelo A. Click Copeland

All ETDs from UAB

ABSTRACT Nearly one in four adults in the United States report living with a disability (Centers for Disease Control and Prevention, 2024). According to the National Center for Educational Statistics (2023), approximately 21 percent of undergraduate students and 11 percent of postbaccalaureate students report having a disability. Students with disabilities in college encounter considerable obstacles that can adversely affect their mental health, academic performance, and general well-being. These obstacles encompass social isolation, stigma, and insufficient personalized support services, resulting in increased levels of anxiety, depression, and dropout rates compared to students without disabilities. Despite the critical need, there is a …

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Mandatory Grade Retention: A Phenomenological Study Of The Lived Experiences Of Principals During The Implementation Of The Alabama Literacy Act, Kiana Billings Coleman Jan 2025

Mandatory Grade Retention: A Phenomenological Study Of The Lived Experiences Of Principals During The Implementation Of The Alabama Literacy Act, Kiana Billings Coleman

All ETDs from UAB

ABSTRACT For over 40 years, the standards-based reform movement has significantly influenced educational policy in the United States (Shanahan, 2014). Educators across the country are under increasing pressure to improve student achievement as states implement policies that link test scores to accountability measures. Recently, the adoption of mandatory grade retention policies has emerged as a popular intervention for addressing low academic performance. Effective leadership is vital to the success of policy initiatives. However, there is limited research on how school principals experience mandatory retention policies. Understanding how administrators navigate retention policies is essential for identifying effective leadership strategies that facilitate …

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Analysing Post-Mortem Interval By Blood Metabolomics, Nishitha Reddy Nishitha Chitla Jan 2025

Analysing Post-Mortem Interval By Blood Metabolomics, Nishitha Reddy Nishitha Chitla

All ETDs from UAB

Accurate estimation of the postmortem interval (PMI) is a critical aspect of forensic investigations, aiding in time-of-death determination. This study employs High-Performance Liquid Chromatography Mass Spectroscopy (HPLCMS) and Gas Chromatography-Mass Spectrometry (GC-MS) to analyze postmortem metabolic changes and identify potential biomarkers for PMI estimation analyses through metabolomics. Blood serum samples from ante mortem samples (AMS) and postmortem samples (PMS) were categorized into Control (0 hrs), Early PMI (25–58 hrs), and Late PMI (92–163 hrs) groups. Multivariate statistical analyses, including Partial Least Squares-Discriminant Analysis (PLS-DA), Variable Importance in Projection (VIP) scoring, and metabolic pathway evaluations, were conducted to assess biochemical alterations …

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Elucidating The Proteolytic Determinants Of Flavivirus Infection, Lochlain C. Corliss Jan 2025

Elucidating The Proteolytic Determinants Of Flavivirus Infection, Lochlain C. Corliss

All ETDs from UAB

Flaviviruses, recently renamed to orthoflaviviruses, are small, enveloped viruses with positive-sense, single-stranded RNA (ssRNA) genomes of about 11 kilobases. Upon cell entry and uncoating, the viral RNA (vRNA) is directly translated at the endoplasmic reticulum (ER) as a single polyprotein that is then processed by the viral and cellular proteases into 10 functional subunits, consisting of three structural proteins and seven nonstructural (NS) proteins. Among the NS proteins are NS2B and NS3, which form the viral protease complex. NS3 consists of a serine protease domain while NS2B is anchored to the ER and contains a cytoplasmic loop that serves as …

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Risk, Promotive, And Protective Factors In Adolescence For Incarceration In Adulthood: A 20 Year Longitudinal Study, Carlos Espinoza Jan 2025

Risk, Promotive, And Protective Factors In Adolescence For Incarceration In Adulthood: A 20 Year Longitudinal Study, Carlos Espinoza

All ETDs from UAB

The high rate of incarceration in the United States presents a public issue that affects individuals, families, and communities. Empirical research has identified several adolescent risk factors linked to an increased likelihood of incarceration in adulthood, such as individual delinquency, peer delinquency, parental antisocial behaviors, and neighborhood disorder. However, much less is known about factors that might promote or protect against incarceration specifically. Factors associated with a reduced likelihood of delinquent behavior (a precursor to incarceration) include higher empathy, prosocial peers, parental nurturance, and neighborhood connectedness. These factors may similarly reduce the risk of incarceration, just as they reduce the …

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Discarded People, Amber Harris Jan 2025

Discarded People, Amber Harris

All ETDs from UAB

ABSTRACT This is the first chapter of the novel, Discarded People, a character-driven story about a group of young Black friends navigating love, identity, and community. As they form deep connections with one another, they face personal struggles that challenge their sense of belonging and self-discovery. The narrative explores themes of family, friendship, and the search for purpose, while highlighting the complexities of building a chosen family amidst personal and societal pressures. In chapter one, the main characters are introduced; Winnie, Franklin, Jelani, Adanna, Eban and Chance. As the characters prepare for their final year in high school while navigating …

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Context-Dependent Functional Connectivity During Attention Orienting And Reorienting: Comparing Individuals With Schizophrenia And Controls, Hyun Freeman Jan 2025

Context-Dependent Functional Connectivity During Attention Orienting And Reorienting: Comparing Individuals With Schizophrenia And Controls, Hyun Freeman

All ETDs from UAB

Attentional deficits are a well-established feature of schizophrenia, impacting various functional domains. Previous research suggested altered connectivity within attention networks may underlie these deficits, but few studies have examined how these net-works dynamically interact during different types of attention processes. In this study, we investigated functional connectivity patterns during attentional orienting and reori-enting to social and nonsocial cues in 25 individuals with schizophrenia and 25 controls. Participants completed a modified Posner spatial cueing task with both social (eyes) and nonsocial (arrows) cues during fMRI scanning. Using generalized psychophysiological interaction analysis with the left lateral occipital cortex (LOC) as a seed …

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