Digital Commons Network^™

Mobula, Bioinspiration, Filter Feeding, Form And Function, J. B. Teeple, S. R. Kahane-Rapport, K. E. Cohen, L. Hamann, J. A. Strother, E. W.M. Paig-Tran

Biological Sciences Faculty Publications

Mobulas (manta and devil rays) are large-scale ram filter feeders that separate planktonic food particles from large volumes of water with minimal clogging. This contrasts with most human-made filters that can suffer from problematic clogging requiring additional mechanisms for clearing blocked surfaces and maintaining performance. Prior studies have shown that mobulas employ a unique mechanism referred to as ricochet separation to filter feed, whereby captive vortices in filter pores cause particles to bounce off the filter surfaces and away from the filter pores. This mechanism enables the filtration of particles smaller than the pore size and reduced clogging. However, few …

Multi-Locas Gwas Mapping And Candidate Gene Analysis Of Anticancer Peptide Lunasin In Soybean (Glycine Max L. Merr), Rikki Locklear, Jennifer Kusumah, Layla Rashad, Felicia Lugaro, Sonia Viera, Nathan Kipyego, Faith Kipkosgei, Daisy Jerop, Shirley Jacquet, Mythy Addelmajid Kassem, Jiazheng Yuan, Elvira De Mejia, Rouf Mian

Biological Sciences Faculty Publications

Soybean (Glycine max) peptide lunasin exhibits significant cancer-preventive, antioxidant, and hypocholesterolemic effects. This study aimed to identify quantitative trait nucleotides (QTNs) associated with lunasin content and to annotate the candidate genes in the soybean genome. The mapping panel of 144 accessions was gathered from the USDA Soybean Germplasm Collection, encompassing diverse geographical origins and genetic backgrounds, and was genotyped using SoySNP50K iSelect Beadchips. The lunasin content in soybean seeds was measured using the enzyme-linked immunosorbent assay (ELISA) method, with lipid-adjusted soybean flour prepared from seeds obtained from the Germplasm Resource Information Network (GRIN) of USDA-ARS in 2003 and …

Herpetofauna Richness, Diversity, And Occurrence At The Northern Ecotone Of Longleaf Pine, Julianne Jones, Dylan Bryant, Erik Yando

Biological Sciences Faculty Publications

Habitat suitability commonly differs between the core and periphery of ecosystems. The longleaf pine ecosystem is recognized for its value in providing habitat to a variety of specialist and endemic species, especially herpetofauna. However, at the northernmost extent of longleaf pine (in southeastern Virginia) little is known about the denizen reptiles and amphibians. Moreover, the remaining longleaf pine ecosystem at the latitudinal ecotone is fragmented amongst a mosaic of other ecosystems. We examined herpetofauna diversity, richness, and capture rates between four focal habitat types—mature longleaf pine, restored longleaf pine, maple-gum swamp, and pocosin-bog—in the Zuni Pine Barrens of southeastern Virginia. …

[Review Of The Book Inscribing Sovereignties: Writing Community In Native North America, By P. H. Round]., Drew Lopenzina

English Faculty Publications

[Introduction] Phillip H. Round's new book follows in a line of intellectual enquiries over the last 20 years, including Hilary Wyss’ Writing Indians (2003), Lisa Brooks’ The Common Pot (2008), my own Red Ink (2012), and Round's previous monograph, Removable Type (2010), that delve into the nature of the written word and how it worked within the context of settler colonialism to transform Indigenous lives on the North American continent. As established by these previous works of scholarship, western literacy was not the miraculous portal into civilization that settler colonial agents often purported it to be. Because Native peoples already …

Codec-M: The Multi-Lingual Manosphere Subcorpus Of The Corpus Of Digital Extremism And Conspiracies, Rachel Mccullough, Daniel Drylie, Mindl Barta, Cass Dykeman, Daniel Smith

English Faculty Publications

In 2023, the U.S. Surgeon General warned the public of the current “loneliness epidemic” and its potential consequences on physical and mental health. One possible consequence of this epidemic is the growth of a movement defined by loneliness and isolation: the incel (“involuntary celibate”) movement. This warning presents a worrying glimpse at the future, as the incel movement, along with other parts of the manosphere, is one that espouses violently misogynist rhetoric which is intrinsically linked to right-wing extremism. While linguistic studies have been conducted on the speech of incels and other constituent movements of the manosphere, few of these …

Hierarchies Of Violence, Victimhood, And Remedy In The Pursuit Of Women's Rights After War, Marie Berry, Milli Lake, Sinduja Raja, Soraya Zarook

English Faculty Publications

Recent postwar recovery efforts have paved the way for reforms that advance women's participation in politics, inclusion in the economy, and access to justice. In this article, we show how a singular emphasis on gender reforms after war that are inattentive to other societal cleavages can leave various forms of marginalization in the shadows. Subnational interviews on the reverberations of gender reforms in five postwar countries expose three hierarchies that structure access to rights for war-affected communities. We reveal which violence is privileged, whose violence is privileged, and which responses are privileged from the perspectives of differently situated war-affected women, …

Demonstrating The Resilience Of Eportfolios In Times Of Disruption: Two International Case Studies, Shari Bowker, Amy Cicchino, Kevin Kelly, Kristina Hoeppner, Christina Mayes, Megan Mize, Christine Slade, Suzanne Schibeci, Sarah Zurhellen

English Faculty Publications

This chapter explores ePortfolios as a resilient practice in higher education during periods of disruption. Drawing on the Support principle from the Digital Ethics Principles in ePortfolios, developed by the Association for Authentic, Experiential, and Evidence-Based Learning’s (AEEBL’s) Digital Ethics Task Force, the authors argue that the student resilience fostered by ePortfolio practices can only be achieved successfully if ePortfolio programs are implemented and supported in a way that makes them resilient as well. Two case studies from Old Dominion University (ODU) in the United States and The University of Queensland (UQ) in Australia demonstrate how both institutions embedded ePortfolio …

"They Just Don't Have The "Doctor" In Front Of Their Name:" Dimensions Of Trust In Physician Assistants, Staci Defibaugh, Leah Onosato

English Faculty Publications

Physician assistants play a major role in healthcare delivery in the United States, yet what we know about how patients perceive the care they receive from PAs is limited. Prior research on patients’ impressions of PAs has focused primarily on survey data, limiting the scope of what we can learn about patient impressions to predetermined, quantifiable categories, and has focused on post-visit impressions of a single encounter. In an attempt to better understand patient impressions, we conducted open-ended, semi-structured interviews with 30 participants prior to their medical visit, focusing on general impressions of PAs. Through an analytic process of reflexive …

Toward A Decolonial Digitality: On Seb Franklin's The Digitally Disposed, Travis Alexander

English Faculty Publications

[Introduction] If the long hot summer of 2020 marked a season of racial reckoning, it was also—now visible in retrospect—a moment for processing with the relation between digital technologies and power. 8:46 after all names not only an event, a murder, but the title of a short digital film. A film, moreover, that has found decisively counterposed audiences in its ongoing afterlives. A forensics of police violence, on the one hand, 8:46 also avails, in the shadier corners of the dark web, the pleasures of a snuff film. In this way, 8:46 is emblematic of a broader, and, perhaps, terminal …

Analog Digital Frame: User Centered Design In Arts-Based Neighborhood Resilience Modeling, David Robledo, Sydney F. Walker, Zlatka Rebolledo Sánchez, Richard Nickel

English Faculty Publications

We explicate a mapping of digital documents through computer machinery as an analog frame for Research and Design in neighborhood environmental literacy, within an applied interdisciplinary ecosystem theory. In the arena of communicating localized climate phenomena and solutions, the design of communication frameworks has provided a core methodology to map climate adaptive conclusions as analogs for actionable community interpretive media. In this experience report, we articulate User Centered Design (UCD) in project research and development, while reporting on difficulties and solutions in shaping an analog digital frame to integrate student driven research and design with mentor based interdisciplinary project theorization. …

Is It Getting Better? An Evaluation Of Two Successive Generations Of Chatgpt In Answering Specialized Vascular Surgery Questions, Dongjin Suh, Quang Le, Leana Dogbe, Kedar Lavingia, Michael Amendola

Department Surgery Faculty Publications

Purpose: Large language models (LLMs) can generate clinically relevant text; however, their performance in highly specialized medical domains remains uncertain. This study evaluated ChatGPT-3.5 and ChatGPT-4 (OpenAI) using vascular surgery board–style questions from the Vascular Education and Self-Assessment Program, version 4 (VESAP4) and compared the two public model versions (June and November 2023).

Materials and Methods: All non-image VESAP4 questions (n=384) were presented independently three times to each model version (ChatGPT-3.5 June/November; ChatGPT-4, June/November). Outcomes included accuracy (proportion correct), consistency (same option letter across all three attempts and “consistently correct”), explanation length (word count), and modes of failure classified for …

Surgical Management Of Gastroenteropancreatic Neuroendocrine Tumors, Lisa M. Kenney, Marybeth Hughes

Department Surgery Faculty Publications

Background/Objectives: Neuroendocrine tumors (NETs) are heterogeneous malignancies arising from enterochromaffin cells that can arise from the gastrointestinal (GI) tract and pancreas. Surgical management is the cornerstone of treatment, with the optimal approach tailored by tumor grade, size, location, and presence of metastasis. This review discusses the current strategies for the surgical management of NETs of the gastroenteropancreatic tract. Methods: A review of the available literature was conducted to evaluate surgical approaches to NETs. Consensus guidelines were incorporated to synthesize evidence-based recommendations. Results: For gastric NETs, surgical approach depends on Rindi Classification, WHO grade, and tumor size, with endoscopic approaches favored …

Therapy-Based Strategies To Support Tummy Time In Infants Post-Hospital Discharge: A Scoping Review Protocol, Ketaki Inamdar, Sonia Khurana

Rehabilitation Sciences Faculty Publications

Tummy time is essential for infant development, yet many caregivers face significant challenges with adherence due to behavioral and contextual barriers. While numerous tummy time interventions exist, a limited understanding of their behavioral components hinders effective replication and implementation. This scoping review aims to identify multidisciplinary interventions used to promote tummy time in infants aged 0–12 months, evaluate their impact on adherence, developmental and health outcomes, and examine the behavior change techniques employed using the Theoretical Domains Framework (TDF). Following the Joanna Briggs Institute (JBI) methodology, a comprehensive search will be conducted in MEDLINE (PubMed), Web of Science Core Collection, …

Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis In The Management Of Intermediate-Risk Pulmonary Embolism: Primary Results Of The Peerless Randomized Controlled Trial, Wissam A. Jaber, Carin F. Gonsalves Md, Stefan Stortecky, Samuel Horr, Ripal T. Gandhi, Keith Pereira, Jay Giri, Sameer J. Khandhar, Khawaja Afzal Ammar, David M. Lasorda, Brian Stegman, Lucas Busch, David J. Dexter, Ezana M. Azene, Nikhil Daga, Fakhir Elmasri, Chandra R. Kunavarapu, Mark E. Rea, Joseph S. Rossi, Joseph Campbell, Jonathan Lindquist, Adam Raskin, Jason C. Smith, Thomas M. Tamlyn, Gabriel A. Hernandez, Parth Rali, Torrey R. Schmidt, Jeffrey T. Bruckel, Juan C. Camacho, Jun Li, Samy Selim, Catalin Toma, Sukhdeep Singh Basra, Brian A. Bergmark, Bhavraj Khalsa, David M. Zlotnick, Jordan Castle, David J. O'Connor, C. Michael Gibson, For The Peerless Committees And Investigators

Department Surgery Faculty Publications

BACKGROUND: There are a lack of randomized controlled trial data comparing outcomes of different catheter-based interventions for intermediate-risk pulmonary embolism.

METHODS: PEERLESS is a prospective, multicenter, randomized controlled trial that enrolled 550 patients with intermediate-risk pulmonary embolism with right ventricular dilatation and additional clinical risk factors randomized 1:1 to treatment with large-bore mechanical thrombectomy (LBMT) or catheter-directed thrombolysis (CDT). The primary end point was a hierarchal win ratio composite of the following (assessed at the sooner of hospital discharge or 7 days after the procedure): (1) all-cause mortality, (2) intracranial hemorrhage, (3) major bleeding, (4) clinical deterioration and/or escalation …

Virtual Learning In Emergency Medicine Residency Programs, Ashley Rider, Laura Oh, Rahul Bhat, Michael Gottlieb, Bruce Lo, Ulemu Luhanga, Shayne Gue, Jason Laenngfeld, Sarah Greenberger, Jeffery Hill, Jonathan Heidt

Department of Emergency Medicine Faculty Publications

During the COVID-19 pandemic, educational systems worldwide faced significant disruptions as in-person learning became unfeasible. In response, many institutions, including graduate medical education programs, swiftly transitioned to virtual learning platforms to adapt to these challenges. The rapid and unplanned pivot in learning format resulted in temporary negative impacts on residency training. Conversely, the experience of the rapid shift may have resulted in some long-term benefits while also preparing programs for future disruptions. This review aimed to discuss the advantages and disadvantages of virtual learning, potential mitigation strategies for the realized disadvantages, and potential areas of future research.

Moderate Heating Renders 7.8-Million-Year-Old Sedimentary Organic Matter Bioavailable, Shuchai Gan, Verena B. Heuer, Frauke Schmidt, Lars Wormer, Faming Wang, Rishi R. Adhikari, Patrick Hatcher, Ann Pearson, Kai-Uwe Hinrichs

Chemistry & Biochemistry Faculty Publications

Marine sediments are a large reservoir of recalcitrant organic matter and host microbes at subsurface depths exceeding 2.4 kilometers and temperatures up to 120°C, yet the mechanisms supplying bioavailable substrates remain unclear. Here, we investigated 7.8-million-year-old sediment from IODP Site C0012 off the Nankai Trough, Japan, through incubations at 20°, 35°, 55°, and 85°C to simulate burial temperatures. Using 3D fluorescence spectroscopy and ultrahigh-resolution mass spectrometry, we tracked changes in dissolved organic matter (DOM). At 35°C, humic-like DOM was released alongside metal ions, exhibiting low bioavailability. At 55°C, abiotic decomposition of humic compounds generated smaller, more bioavailable DOM, promoting fermentation. …

The Impact Of Ultra-Processed Foods On Cardiovascular Diseases And Cancer: Epidemiological And Mechanistic Insights, Olorunfemi Oyewole Babalola, Ebenezer Akinnusi, Paul Olamide Ottu, Kpomah Bridget, Godspower Oyubu, Samuel Ayomikun Ajiboye, Sakariyau Adio Waheed, Amafili Chibuzo Collette, Hameedah Oluwatoyin Adebimpe, Chibuzo Valentine Nwokafor, Ebenezer Ayomide Oni, Precious Olayinka Aturamu, Opeyemi Iwaloye

Chemistry & Biochemistry Faculty Publications

Ultra-processed foods (UPFs) are increasingly recognized as contributors to the pathogenesis of cardiovascular diseases (CVDs) and cancer due to their adverse compositional and mechanistic effects. UPFs, distinguished by their high content of unhealthy fats, sodium, refined sugars, and synthetic additives, significantly increase dyslipidemia, hypertension, and obesity, which are key risk factors for CVDs. Chronic consumption leads to systemic inflammation, gut microbiota dysbiosis, endothelial dysfunction, and oxidative stress. Additives such as artificial sweeteners and sodium nitrites in UPFs are associated with carcinogenesis through mechanisms involving genotoxicity and promotion of inflammatory microenvironments. This review critically evaluates existing epidemiological, mechanistic, and clinical evidence …

Amorphous Quininium Aspirinate From Neat Mechanochemistry: Diffracting Nanocrystalline Domains And Quick Recrystallization Upon Exposure To Solvent Vapours, Silvina Pagola, James Howard, Johannes Merkelbach, Danny Stam

Chemistry & Biochemistry Faculty Publications

Quininium aspirinate is mechanochemically prepared as a crystalline solid by liquid-assisted grinding, or as an amorphous phase (as determined by X-ray powder diffraction), by neat grinding or neat ball milling. Our previous work demonstrated using FT-IR spectroscopy that a mechanochemical reaction had occurred in the mechanically treated neat mixtures. Herein is reported that microcrystal electron diffraction (microED) afforded the discovery of two diffracting micron-size particles in the amorphous powder synthesized by manual grinding, among a majority of non-diffracting particles. Remarkably, microED data of one of them led to the known lattice parameters of quininium aspirinate. Furthermore, this so-called 'X-ray amorphous' …

Calculation Of Proton Transmembrane-Electrostatic Interaction Force And Elucidation Of The Water Droplet Experiment With A Transient Protonic Front, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

The “transmembrane-electrostatically localized proton(s)/cation(s) charge(s) (TELC(s), also known as TELP(s)) model” may serve as a theoretical framework to explain protonic cell energetics including both delocalized and localized protonic couplings. TELCs are held by their corresponding transmembrane-electrostatically localized hydroxides anions (TELAs) across the membrane through mutual transmembrane-electrostatic attractive force, which is now calculated to be in the range from 1.96 × 10⁻¹¹ to 2.28 × 10⁻¹¹ newtons (N) across a 2.5 nm thick membrane in a range of transmembrane potential from 10 to 200 mV. At a moderate transmembrane potential (100 mV), the protonic transmembrane attractive force is now calculated to …

A Comparison Of Microcrystal Electron Diffraction And X-Ray Powder Diffraction For The Structural Analysis Of Metal-Organic Frameworks, Erik Biehler, Silvana Pagola, Daniel Stam, Johannes Merkelbach, Christian Jandl, Tarek M. Abdel-Fattah

Chemistry & Biochemistry Faculty Publications

This study successfully implemented microcrystal electron diffraction (microED) and X-ray powder diffraction (XRPD) for the crystal structure determination of a new phase, TAF-CNU-1, Ni(C₈H₄O₄)·3H₂O, solved by microED from single microcrystals in the powder and refined at the kinematic and dynamic electron diffraction theory levels. This nickel metal–organic framework (MOF), together with its cobalt and manganese analogues with formula M (C₈H₄O₄)·2H₂O with M = Mn ^II or Co^II, were synthesized in aqueous media as one-pot preparations from the corresponding hydrated metal chlorides and sodium terephthalate, as a promising `green' synthetic route to moisture-stable MOFs. The crystal structures of the …

Extended Inter-Laboratory Characterization Of The New Coastal Seawater Dissolved Organic Matter Reference Material Trm-0522, Alexander J. Craig, Lydia Babcock-Adams, Maxime C. Bridoux, Charlotte Brun, Juliana D'Andrilli, Aleksandar I. Goranov, Patrick G. Hatcher, Oliver Lechtenfeld, Hang Li, Rebecca Matos, Garrett Mckay, Amy M. Mckenna, Madelyn Miller, Sasha Wagner, Margot E. White, Alexander Zherebker, Jeffrey A. Hawkes

Chemistry & Biochemistry Faculty Publications

Dissolved organic matter (DOM) reference materials are critical to ensuring reliable comparability of measurements across experiments and between labs. TRM-0522, isolated in 2022 from 45 m deep seawater off of Sweden’s west coast, fills the niche of a previously unavailable coastal marine DOM reference material. After its isolation, we detailed a limited number of metrics for TRM-0522, initially disclosing Orbitrap high-resolution mass spectrometry, nuclear magnetic resonance, carbon proportion, absorbance, and fluorescence data. With TRM-0522 becoming more widely used, a variety of labs have generated different metrics that help to characterize and define the chemical properties of this coastal reference material. …

Co₂ Isotopologues From The Ace Satellite, D. English, P. Bernath, C. Boone

Chemistry & Biochemistry Faculty Publications

Carbon dioxide isotopologues have been studied thoroughly in the troposphere. In the stratosphere, the minor oxygen CO₂ isotopologues have anomalous abundances due to their exchange reactions with isotopically fractionated ozone, differentiating them from tropospheric CO₂. Previously a model predicted that this anomalous isotopic abundance continues into the mesosphere but lacked verification from experimental observations. Here we use the Atmospheric Chemistry Experiment Fourier Transform Spectrometer which records infrared transmittance spectra of the Earth's limb from low Earth orbit using solar occultation. These infrared spectra provide measurements of global CO₂ isotopologue volume mixing ratios (VMRs) from the upper troposphere to the lower …

An E. Coli Two-Hybrid System To Investigate Human Protein-Protein Interactions, Rebecca M. Richardson, Sarah M. Ho, Lane Tong, Morgan G. Daniels, Steven M. Pascal

Chemistry & Biochemistry Faculty Publications

Abstract

The LexA-E. coli two-hybrid (LexA-E2H) system was initially developed to study interactions between microbial proteins in an Escherichia coli (E. coli) environment. We here demonstrate its utility for studying mammalian protein interactions. Specifically, this study uses LexA-E2H to provide the first direct and quantitative validation of Glucose Regulated Protein 78 (GRP78) binding to the cleaved-Prostate Apoptosis Response 4 (cl-Par-4) tumor suppressor. Furthermore, the results establish that this interaction does not require phosphorylation of either protein. MacConkey agar was used for initial detection of the interaction through colorimetric colony screening, distinguishing pale white-pink colonies (+ interaction) from …

Analysis Of Aerosols In The Asian Monsoon Anticyclone As Observed By The Atmospheric Chemistry Experiment, M. Lecours, R. Dodangodage, C. D. Boone, P. F. Bernath

Chemistry & Biochemistry Faculty Publications

During the Asian summer monsoon season, pollutants from the lower troposphere are transported through deep convection to the upper troposphere and lower stratosphere. Surface pollutants such as CO are transported upward and trapped in the anticyclone during this unique atmospheric phenomenon. Associated with the anticyclone is a layer of enhanced aerosols located near the tropopause often referred to as the Asian tropopause aerosol layer (ATAL). The chemical and physical properties of aerosols in the ATAL are not yet fully understood as direct observations of the aerosols are limited. The Atmospheric Chemistry Experiment (ACE) is a satellite mission that provides high-resolution …

From Biophysics To Cellular Function: Neural Telcs-Membrane-Anions Capacitor Transmembrane Potential, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

Based on the transmembrane-electrostatically localized protons/cations charges (TELCs) theory, neural transmembrane potential including both resting and action potential is now well elucidated as the voltage contributed by the TELCs-membrane-anions capacitor biophysics in a neuron. Accordingly, neural transmembrane potential has an inverse relationship with TELCs surface density, which may represent a substantial progress in bettering the fundamental understanding of neuroscience. In this article, I will present a review on the latest development of the TELCs neural transmembrane potential theory and address Silverstein’s interesting arguments regarding the TELCs model that may constitute a complementary development to both the Hodgkin-Huxley classic cable theory …

Metathesis Or Isomerization: Counteranion Directed Reactivity Of Grubbs I, Paul D. Miller, Joe B. Calkins, Craig A. Bayse, Trandon A. Bender

Chemistry & Biochemistry Faculty Publications

Catalytic isomerization of alkenes has garnered interest for many years, but there are remaining challenges when it comes to thermodynamic selectivity and uncontrolled isomerization. Nonbiased substrates, be it sterically or thermodynamically, remain challenging for many catalysts, with a few examples available in the more modern literature. Herein, we present the controlled isomerization of linear alkenes with a cocatalytic mixture of commercially available catalyst and reagents: Grubbs I, tris(pentafluorophenyl)borane, and triethylsilane. DFT calculations indicate that an observed alkylidyne hydride intermediate is in rapid equilibrium with an alkylidene that binds the alkene substrate. This combination results in a pi-acidic metal and a …

Stack Bonding In Pentacene And Its Derivatives, Craig A. Bayse

Chemistry & Biochemistry Faculty Publications

Understanding the nature of π-stacking interactions is important to molecular recognition, self-assembly, and organic semiconductors. The stack bonding order (SBO) model of π-stacking has shown that the conformations of dimers occur when the combinations of monomer MOs are overall stack bonding in character. DFT calculations show that minima found on the potential energy surface for the π-stacked dimers of pentacene and perfluoropentacene occur when the dimer MOs are constructed from combinations of monomer MOs with an allowed SBO. An ex-amination of the MOs of π-stacked dimers extracted from X-ray structures of alkynyl derivatives like TIPS-pentacene pack at one or more …

Molecular Characterization Of Humic And Fulvic Acids On Watterlogged And Well-Drained Amazonian Podzols, Amanda M. Tadini, Aleksandar I. Goranov, Stéphane Mounier, Débora M.B.P. Milori, Célia R. Montes, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

The Amazon rainforest is the largest tropical rainforest in the world. Amazonian Podzol soils, characteristic of this region, are known to store substantial amounts of organic carbon in both their surface and deep horizons. Despite decades of research, the molecular-level composition of these soils remains uncharacterized. This study addresses this knowledge gap by employing ultrahigh resolution mass spectrometry, namely, Fourier transform–ion cyclotron resonance–mass spectrometry (FT-ICR-MS), to determine the molecular composition of humic acid (HA) and fulvic acid (FA) fractions from two Amazonian Podzol profiles of varying levels of groundwater exposure (waterlogged vs well-drained). In the waterlogged soil compounds containing nitrogen, …

Protonic Capacitor Cell Energetics: Transmembrane-Electrostatically Localized Protons/Cations, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

The transmembrane-electrostatically localized protons/cations charges (TELPs/TELCs) theory can serve as a theoretical framework to better explain cell electrophysiology and elucidate bioenergetic systems including both delocalized and localized protonic coupling. According to the TELCs model, the excess positive charges of TELCs at one side of the membrane are balanced by the excess negative charges of transmembrane-electrostatically localized hydroxides anions (TELAs) at the other side of the membrane. Through the TELCs-membrane-TELAs capacitor model, the energetics of oxidative phosphorylation have recently been better elucidated in mitochondria and alkalophilic bacteria, leading to the identification of a novel Type-B energetic process. Both the TELCs model …

Deciphering The Chemistry Of Condensed Aromatic "Black" Carbon And Nitrogen In Amazonian Anthrosols, João Vitor Dos Santos, Aleksandar I. Goranov, Laís G. Fregolente, Marcia C. Bisinoti, Zhenhuan Sun, Klaus Schmidt-Rohr, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Amazonian anthrosols are renowned for their high fertility and dark color, properties primarily attributed to the abundance of condensed aromatic carbon (ConAC) in the soil organic matter. ConAC, commonly referred to as black carbon, play a key role in the stability and nutrient retention of these soils. However, the processes governing the formation of ConAC and its transformation into oxygenated derivatives remain poorly understood. In this study, we used multiple analytical platforms to investigate the chemistry of ConAC-rich humic acids (HA) extracted from Terra Mulata de Indio, a type of Amazonian anthrosol. The results reveal that ConAC are predominantly …